

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of activation of Janus kinase activity (GO:0010533) | 5.51620433 |
| 2 | proteasome assembly (GO:0043248) | 5.29959065 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 4.88772935 |
| 4 | cytidine catabolic process (GO:0006216) | 4.87543971 |
| 5 | cytidine deamination (GO:0009972) | 4.87543971 |
| 6 | cytidine metabolic process (GO:0046087) | 4.87543971 |
| 7 | glyoxylate metabolic process (GO:0046487) | 4.81557495 |
| 8 | DNA deamination (GO:0045006) | 4.64814908 |
| 9 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.39619933 |
| 10 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.22530688 |
| 11 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.12131904 |
| 12 | IMP biosynthetic process (GO:0006188) | 4.11312714 |
| 13 | rRNA modification (GO:0000154) | 4.10856771 |
| 14 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.08747829 |
| 15 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.06696957 |
| 16 | DNA catabolic process, exonucleolytic (GO:0000738) | 4.00531068 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.99410115 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.98732760 |
| 19 | NADH dehydrogenase complex assembly (GO:0010257) | 3.96183761 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.96183761 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.96183761 |
| 22 | protein peptidyl-prolyl isomerization (GO:0000413) | 3.95203139 |
| 23 | rRNA methylation (GO:0031167) | 3.94885063 |
| 24 | pseudouridine synthesis (GO:0001522) | 3.83656362 |
| 25 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.79022906 |
| 26 | GTP biosynthetic process (GO:0006183) | 3.78538069 |
| 27 | nuclear pore organization (GO:0006999) | 3.77096571 |
| 28 | protein deneddylation (GO:0000338) | 3.76438026 |
| 29 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.74941609 |
| 30 | IMP metabolic process (GO:0046040) | 3.73516117 |
| 31 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.70643379 |
| 32 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.70643379 |
| 33 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.70615737 |
| 34 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.67181192 |
| 35 | cullin deneddylation (GO:0010388) | 3.65319735 |
| 36 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.65194102 |
| 37 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.62674229 |
| 38 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.62674229 |
| 39 | protein complex biogenesis (GO:0070271) | 3.60444194 |
| 40 | UTP biosynthetic process (GO:0006228) | 3.60241746 |
| 41 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.59842358 |
| 42 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.59842358 |
| 43 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.59842358 |
| 44 | glycine metabolic process (GO:0006544) | 3.59407440 |
| 45 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.58967701 |
| 46 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.58967701 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.58553530 |
| 48 | termination of RNA polymerase III transcription (GO:0006386) | 3.58553530 |
| 49 | regulation of chronic inflammatory response (GO:0002676) | 3.54860153 |
| 50 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.54272991 |
| 51 | eosinophil chemotaxis (GO:0048245) | 3.53220877 |
| 52 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.47081333 |
| 53 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.45575340 |
| 54 | ATP synthesis coupled proton transport (GO:0015986) | 3.45575340 |
| 55 | regulation of mononuclear cell migration (GO:0071675) | 3.42904421 |
| 56 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.41235733 |
| 57 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.38919328 |
| 58 | tetrahydrofolate metabolic process (GO:0046653) | 3.35074057 |
| 59 | positive regulation of T cell chemotaxis (GO:0010820) | 3.34311248 |
| 60 | regulation of T cell chemotaxis (GO:0010819) | 3.34311248 |
| 61 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.33680136 |
| 62 | negative regulation of ligase activity (GO:0051352) | 3.33680136 |
| 63 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.32876543 |
| 64 | UTP metabolic process (GO:0046051) | 3.31033192 |
| 65 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.29362847 |
| 66 | establishment of integrated proviral latency (GO:0075713) | 3.28211462 |
| 67 | regulation of cellular amine metabolic process (GO:0033238) | 3.27060770 |
| 68 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.22224879 |
| 69 | peptidyl-proline modification (GO:0018208) | 3.21655825 |
| 70 | mitotic metaphase plate congression (GO:0007080) | 3.21247913 |
| 71 | nucleobase biosynthetic process (GO:0046112) | 3.18983779 |
| 72 | ribosome assembly (GO:0042255) | 3.18904984 |
| 73 | DNA integration (GO:0015074) | 3.18351030 |
| 74 | DNA damage response, detection of DNA damage (GO:0042769) | 3.17122621 |
| 75 | serine family amino acid catabolic process (GO:0009071) | 3.16991021 |
| 76 | L-phenylalanine catabolic process (GO:0006559) | 3.16159918 |
| 77 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.16159918 |
| 78 | regulation of macrophage chemotaxis (GO:0010758) | 3.15611246 |
| 79 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.15316430 |
| 80 | L-phenylalanine metabolic process (GO:0006558) | 3.15316430 |
| 81 | eosinophil migration (GO:0072677) | 3.14946061 |
| 82 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 3.13846185 |
| 83 | positive regulation of ligase activity (GO:0051351) | 3.11337371 |
| 84 | serine family amino acid metabolic process (GO:0009069) | 3.09406792 |
| 85 | purine nucleobase biosynthetic process (GO:0009113) | 3.06396025 |
| 86 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.02882513 |
| 87 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.02533218 |
| 88 | 7-methylguanosine mRNA capping (GO:0006370) | 2.93656134 |
| 89 | tRNA aminoacylation (GO:0043039) | 2.91863256 |
| 90 | amino acid activation (GO:0043038) | 2.91863256 |
| 91 | positive regulation of cell cycle arrest (GO:0071158) | 2.89065932 |
| 92 | metallo-sulfur cluster assembly (GO:0031163) | 2.88605905 |
| 93 | iron-sulfur cluster assembly (GO:0016226) | 2.88605905 |
| 94 | sterol biosynthetic process (GO:0016126) | 2.88270349 |
| 95 | tRNA aminoacylation for protein translation (GO:0006418) | 2.86412612 |
| 96 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.86035148 |
| 97 | RNA capping (GO:0036260) | 2.85557910 |
| 98 | 7-methylguanosine RNA capping (GO:0009452) | 2.85557910 |
| 99 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.84737777 |
| 100 | positive regulation of T cell apoptotic process (GO:0070234) | 2.84737593 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 6.03199810 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.86689267 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.56528372 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.45781264 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.61928223 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.43824078 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.40436474 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.12507923 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.10166498 |
| 10 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 3.02729843 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.01610496 |
| 12 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.80593113 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.77314864 |
| 14 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.75231987 |
| 15 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.71721264 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.64852008 |
| 17 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.54380069 |
| 18 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.50760936 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.41709760 |
| 20 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.28415378 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.25513701 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.25453782 |
| 23 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.24924179 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.24127213 |
| 25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.15838136 |
| 26 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.11342114 |
| 27 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.11049165 |
| 28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.11006432 |
| 29 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.03305186 |
| 30 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.97482631 |
| 31 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.95391145 |
| 32 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.87144912 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.86362857 |
| 34 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.85375620 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.79195307 |
| 36 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.79072918 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.71374350 |
| 38 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.69495014 |
| 39 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.64991155 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.62078611 |
| 41 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.61181049 |
| 42 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.57635065 |
| 43 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.55608651 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.55005004 |
| 45 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54531429 |
| 46 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.51900068 |
| 47 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.51240687 |
| 48 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.51071453 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.46703573 |
| 50 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.44543919 |
| 51 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.38868346 |
| 52 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.38649778 |
| 53 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.35453741 |
| 54 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.34296912 |
| 55 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.30917245 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28552608 |
| 57 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.26098661 |
| 58 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.25554792 |
| 59 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.25234047 |
| 60 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24220765 |
| 61 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22321448 |
| 62 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.20812554 |
| 63 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.14465529 |
| 64 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.09229692 |
| 65 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.08781207 |
| 66 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.04725588 |
| 67 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.04182086 |
| 68 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.03112637 |
| 69 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.02740802 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01364350 |
| 71 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.97166208 |
| 72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97000297 |
| 73 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.94841068 |
| 74 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.94810482 |
| 75 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94559394 |
| 76 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.91640702 |
| 77 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.90819958 |
| 78 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.88785123 |
| 79 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87864799 |
| 80 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.87791339 |
| 81 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.87687480 |
| 82 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.86478568 |
| 83 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.85200095 |
| 84 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.84485341 |
| 85 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.81271163 |
| 86 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.81106378 |
| 87 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.80837251 |
| 88 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.77917673 |
| 89 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.77520713 |
| 90 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.76631092 |
| 91 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.76579193 |
| 92 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.75024569 |
| 93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.74447438 |
| 94 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.74102663 |
| 95 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.74021082 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.72621254 |
| 97 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.72081483 |
| 98 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.72045099 |
| 99 | GATA3_26560356_Chip-Seq_TH2_Human | 0.71119156 |
| 100 | EWS_26573619_Chip-Seq_HEK293_Human | 0.70512710 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 4.64575440 |
| 2 | MP0002139_abnormal_hepatobiliary_system | 4.38209489 |
| 3 | MP0003195_calcinosis | 3.60555510 |
| 4 | MP0002163_abnormal_gland_morphology | 3.33292171 |
| 5 | MP0002876_abnormal_thyroid_physiology | 3.30088215 |
| 6 | MP0003693_abnormal_embryo_hatching | 3.26784481 |
| 7 | MP0009697_abnormal_copulation | 3.25772765 |
| 8 | MP0005360_urolithiasis | 3.25137693 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 3.08069044 |
| 10 | MP0008058_abnormal_DNA_repair | 2.86033325 |
| 11 | MP0005084_abnormal_gallbladder_morpholo | 2.83377536 |
| 12 | MP0003806_abnormal_nucleotide_metabolis | 2.78246348 |
| 13 | MP0003186_abnormal_redox_activity | 2.45835523 |
| 14 | MP0008789_abnormal_olfactory_epithelium | 2.36031266 |
| 15 | MP0004957_abnormal_blastocyst_morpholog | 2.28079601 |
| 16 | MP0005085_abnormal_gallbladder_physiolo | 2.24752897 |
| 17 | MP0001764_abnormal_homeostasis | 2.20823011 |
| 18 | MP0003950_abnormal_plasma_membrane | 2.17337503 |
| 19 | MP0001529_abnormal_vocalization | 2.16320135 |
| 20 | MP0005379_endocrine/exocrine_gland_phen | 2.05243661 |
| 21 | MP0003252_abnormal_bile_duct | 2.04158460 |
| 22 | MP0001661_extended_life_span | 1.94402361 |
| 23 | MP0010094_abnormal_chromosome_stability | 1.85732705 |
| 24 | MP0005332_abnormal_amino_acid | 1.84116185 |
| 25 | MP0009333_abnormal_splenocyte_physiolog | 1.75674237 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.72459988 |
| 27 | MP0001919_abnormal_reproductive_system | 1.72098646 |
| 28 | MP0005499_abnormal_olfactory_system | 1.70683070 |
| 29 | MP0005394_taste/olfaction_phenotype | 1.70683070 |
| 30 | MP0005671_abnormal_response_to | 1.65629668 |
| 31 | MP0003718_maternal_effect | 1.62288654 |
| 32 | MP0003868_abnormal_feces_composition | 1.62125943 |
| 33 | MP0005365_abnormal_bile_salt | 1.59818912 |
| 34 | MP0005167_abnormal_blood-brain_barrier | 1.55446399 |
| 35 | MP0005377_hearing/vestibular/ear_phenot | 1.48404173 |
| 36 | MP0003878_abnormal_ear_physiology | 1.48404173 |
| 37 | MP0006036_abnormal_mitochondrial_physio | 1.44679048 |
| 38 | MP0008932_abnormal_embryonic_tissue | 1.40108382 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.39003101 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.38386850 |
| 41 | MP0008872_abnormal_physiological_respon | 1.37461750 |
| 42 | MP0003786_premature_aging | 1.27351117 |
| 43 | MP0000465_gastrointestinal_hemorrhage | 1.25401388 |
| 44 | MP0005253_abnormal_eye_physiology | 1.23353334 |
| 45 | MP0001485_abnormal_pinna_reflex | 1.22150035 |
| 46 | MP0000490_abnormal_crypts_of | 1.17798715 |
| 47 | MP0001984_abnormal_olfaction | 1.17793888 |
| 48 | MP0005389_reproductive_system_phenotype | 1.15454951 |
| 49 | MP0008877_abnormal_DNA_methylation | 1.08300019 |
| 50 | MP0006035_abnormal_mitochondrial_morpho | 1.03291527 |
| 51 | MP0005636_abnormal_mineral_homeostasis | 1.00948503 |
| 52 | MP0010386_abnormal_urinary_bladder | 1.00835522 |
| 53 | MP0001849_ear_inflammation | 1.00832200 |
| 54 | MP0003763_abnormal_thymus_physiology | 1.00592060 |
| 55 | MP0003011_delayed_dark_adaptation | 0.99139116 |
| 56 | MP0003221_abnormal_cardiomyocyte_apopto | 0.97586765 |
| 57 | MP0005408_hypopigmentation | 0.91558845 |
| 58 | MP0003111_abnormal_nucleus_morphology | 0.90483689 |
| 59 | MP0005220_abnormal_exocrine_pancreas | 0.87992408 |
| 60 | MP0004084_abnormal_cardiac_muscle | 0.87564027 |
| 61 | MP0005083_abnormal_biliary_tract | 0.84857014 |
| 62 | MP0006072_abnormal_retinal_apoptosis | 0.83958060 |
| 63 | MP0002102_abnormal_ear_morphology | 0.83686839 |
| 64 | MP0005319_abnormal_enzyme/_coenzyme | 0.80801047 |
| 65 | MP0005410_abnormal_fertilization | 0.79894297 |
| 66 | MP0000427_abnormal_hair_cycle | 0.79179035 |
| 67 | MP0004147_increased_porphyrin_level | 0.78448184 |
| 68 | MP0000647_abnormal_sebaceous_gland | 0.75034683 |
| 69 | MP0003077_abnormal_cell_cycle | 0.74081643 |
| 70 | MP0010329_abnormal_lipoprotein_level | 0.73753807 |
| 71 | MP0005187_abnormal_penis_morphology | 0.73458497 |
| 72 | MP0001727_abnormal_embryo_implantation | 0.72606057 |
| 73 | MP0005551_abnormal_eye_electrophysiolog | 0.72023508 |
| 74 | MP0000609_abnormal_liver_physiology | 0.70335352 |
| 75 | MP0005330_cardiomyopathy | 0.70317360 |
| 76 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.69559548 |
| 77 | MP0002090_abnormal_vision | 0.66782760 |
| 78 | MP0002723_abnormal_immune_serum | 0.66759692 |
| 79 | MP0001853_heart_inflammation | 0.66380562 |
| 80 | MP0005395_other_phenotype | 0.66124435 |
| 81 | MP0002909_abnormal_adrenal_gland | 0.63711465 |
| 82 | MP0002938_white_spotting | 0.62354680 |
| 83 | MP0010234_abnormal_vibrissa_follicle | 0.62334978 |
| 84 | MP0001790_abnormal_immune_system | 0.60757642 |
| 85 | MP0005387_immune_system_phenotype | 0.60757642 |
| 86 | MP0004782_abnormal_surfactant_physiolog | 0.60311600 |
| 87 | MP0009643_abnormal_urine_homeostasis | 0.59877081 |
| 88 | MP0008057_abnormal_DNA_replication | 0.59843747 |
| 89 | MP0001348_abnormal_lacrimal_gland | 0.59055878 |
| 90 | MP0000358_abnormal_cell_content/ | 0.58630554 |
| 91 | MP0003941_abnormal_skin_development | 0.57925744 |
| 92 | MP0001346_abnormal_lacrimal_gland | 0.57728288 |
| 93 | MP0004742_abnormal_vestibular_system | 0.57643035 |
| 94 | MP0008007_abnormal_cellular_replicative | 0.56950637 |
| 95 | MP0001666_abnormal_nutrient_absorption | 0.56748981 |
| 96 | MP0002019_abnormal_tumor_incidence | 0.56449229 |
| 97 | MP0002160_abnormal_reproductive_system | 0.56056185 |
| 98 | MP0000685_abnormal_immune_system | 0.55942469 |
| 99 | MP0002210_abnormal_sex_determination | 0.55703078 |
| 100 | MP0008469_abnormal_protein_level | 0.54844400 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased serum pyruvate (HP:0003542) | 5.84426037 |
| 2 | Abnormality of glycolysis (HP:0004366) | 5.35507293 |
| 3 | Abnormal gallbladder physiology (HP:0012438) | 4.68532917 |
| 4 | Cholecystitis (HP:0001082) | 4.68532917 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.36284194 |
| 6 | Oral leukoplakia (HP:0002745) | 4.27185201 |
| 7 | Increased CSF lactate (HP:0002490) | 4.21556218 |
| 8 | Hepatocellular necrosis (HP:0001404) | 4.17655505 |
| 9 | Mitochondrial inheritance (HP:0001427) | 4.08507030 |
| 10 | Acute encephalopathy (HP:0006846) | 4.00002649 |
| 11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.94065049 |
| 12 | Hepatic necrosis (HP:0002605) | 3.79716675 |
| 13 | Cerebral edema (HP:0002181) | 3.68059521 |
| 14 | Reduced antithrombin III activity (HP:0001976) | 3.55083155 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.51879410 |
| 16 | Abnormality of alanine metabolism (HP:0010916) | 3.50857699 |
| 17 | Hyperalaninemia (HP:0003348) | 3.50857699 |
| 18 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.50857699 |
| 19 | Increased serum lactate (HP:0002151) | 3.20793149 |
| 20 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.12458154 |
| 21 | Deep venous thrombosis (HP:0002625) | 3.07373156 |
| 22 | Opisthotonus (HP:0002179) | 3.04309657 |
| 23 | Abnormality of the pons (HP:0007361) | 2.93736950 |
| 24 | Hypoplasia of the pons (HP:0012110) | 2.89823785 |
| 25 | Entropion (HP:0000621) | 2.88392044 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.86800265 |
| 27 | Hypoproteinemia (HP:0003075) | 2.78712373 |
| 28 | Lipid accumulation in hepatocytes (HP:0006561) | 2.74488685 |
| 29 | Leukodystrophy (HP:0002415) | 2.74193919 |
| 30 | Prolonged partial thromboplastin time (HP:0003645) | 2.71115226 |
| 31 | Dyschromatopsia (HP:0007641) | 2.69616412 |
| 32 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.66177205 |
| 33 | Cutaneous melanoma (HP:0012056) | 2.64899494 |
| 34 | Increased hepatocellular lipid droplets (HP:0006565) | 2.63305575 |
| 35 | Increased intramyocellular lipid droplets (HP:0012240) | 2.62999907 |
| 36 | Cerebral palsy (HP:0100021) | 2.59666865 |
| 37 | Hypobetalipoproteinemia (HP:0003563) | 2.56602138 |
| 38 | Abnormality of placental membranes (HP:0011409) | 2.54317269 |
| 39 | Amniotic constriction ring (HP:0009775) | 2.54317269 |
| 40 | Palpitations (HP:0001962) | 2.52797960 |
| 41 | Lactic acidosis (HP:0003128) | 2.51123193 |
| 42 | Methylmalonic acidemia (HP:0002912) | 2.50673463 |
| 43 | Respiratory failure (HP:0002878) | 2.50181624 |
| 44 | Abnormality of methionine metabolism (HP:0010901) | 2.48453248 |
| 45 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.44141495 |
| 46 | Abnormal biliary tract physiology (HP:0012439) | 2.43828128 |
| 47 | Bile duct proliferation (HP:0001408) | 2.43828128 |
| 48 | Methylmalonic aciduria (HP:0012120) | 2.38748804 |
| 49 | Microvesicular hepatic steatosis (HP:0001414) | 2.38318296 |
| 50 | Lethargy (HP:0001254) | 2.37572006 |
| 51 | Aplastic anemia (HP:0001915) | 2.34827003 |
| 52 | Increased muscle lipid content (HP:0009058) | 2.33045956 |
| 53 | Intrahepatic cholestasis (HP:0001406) | 2.31635241 |
| 54 | Exercise intolerance (HP:0003546) | 2.31434150 |
| 55 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.26012373 |
| 56 | Sparse eyelashes (HP:0000653) | 2.24994184 |
| 57 | CNS demyelination (HP:0007305) | 2.24929949 |
| 58 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.24843931 |
| 59 | Spastic paraparesis (HP:0002313) | 2.23538581 |
| 60 | Type I transferrin isoform profile (HP:0003642) | 2.18733681 |
| 61 | CNS hypomyelination (HP:0003429) | 2.17033981 |
| 62 | Abnormality of serum amino acid levels (HP:0003112) | 2.16681223 |
| 63 | Rough bone trabeculation (HP:0100670) | 2.16654689 |
| 64 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.09933642 |
| 65 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.09933642 |
| 66 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.07863971 |
| 67 | Dicarboxylic aciduria (HP:0003215) | 2.07863971 |
| 68 | Renal Fanconi syndrome (HP:0001994) | 2.06451698 |
| 69 | Optic disc pallor (HP:0000543) | 2.04502884 |
| 70 | Hyperglycinemia (HP:0002154) | 2.03783229 |
| 71 | Testicular atrophy (HP:0000029) | 2.03137854 |
| 72 | Generalized aminoaciduria (HP:0002909) | 2.02032972 |
| 73 | Rhabdomyolysis (HP:0003201) | 1.99563464 |
| 74 | Prominent metopic ridge (HP:0005487) | 1.98709954 |
| 75 | Hemiplegia (HP:0002301) | 1.96445175 |
| 76 | Cerebral hypomyelination (HP:0006808) | 1.95273536 |
| 77 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.91812423 |
| 78 | Metabolic acidosis (HP:0001942) | 1.89440491 |
| 79 | Abnormality of urine glucose concentration (HP:0011016) | 1.87556294 |
| 80 | Glycosuria (HP:0003076) | 1.87556294 |
| 81 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.85904086 |
| 82 | Cholelithiasis (HP:0001081) | 1.85725725 |
| 83 | Type 2 muscle fiber atrophy (HP:0003554) | 1.85476104 |
| 84 | Abnormality of the metopic suture (HP:0005556) | 1.85112616 |
| 85 | Respiratory difficulties (HP:0002880) | 1.84239377 |
| 86 | Emotional lability (HP:0000712) | 1.83910140 |
| 87 | Vacuolated lymphocytes (HP:0001922) | 1.82922542 |
| 88 | Hyperammonemia (HP:0001987) | 1.80137161 |
| 89 | Inability to walk (HP:0002540) | 1.77889961 |
| 90 | Renal cortical cysts (HP:0000803) | 1.77278466 |
| 91 | Parakeratosis (HP:0001036) | 1.75265607 |
| 92 | Abnormal gallbladder morphology (HP:0012437) | 1.74662329 |
| 93 | Abnormality of nucleobase metabolism (HP:0010932) | 1.74434543 |
| 94 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.73037732 |
| 95 | Abnormality of the labia minora (HP:0012880) | 1.70742999 |
| 96 | Muscle fiber atrophy (HP:0100295) | 1.70304796 |
| 97 | Abnormality of T cell number (HP:0011839) | 1.68680356 |
| 98 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.68430882 |
| 99 | Renal tubular dysfunction (HP:0000124) | 1.67402323 |
| 100 | Myoglobinuria (HP:0002913) | 1.67341707 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NEK1 | 7.27950835 |
| 2 | VRK2 | 4.20040610 |
| 3 | TSSK6 | 3.73323402 |
| 4 | CCNB1 | 3.42673159 |
| 5 | TLK1 | 3.40639222 |
| 6 | ZAK | 3.34991737 |
| 7 | DAPK2 | 2.87506718 |
| 8 | VRK1 | 2.66790844 |
| 9 | BUB1 | 2.65644415 |
| 10 | NME1 | 2.41426085 |
| 11 | MAP4K2 | 2.29797302 |
| 12 | MST4 | 2.27680510 |
| 13 | MUSK | 2.13806801 |
| 14 | TAF1 | 1.80963938 |
| 15 | INSRR | 1.72123545 |
| 16 | CDC7 | 1.67044149 |
| 17 | PIK3CG | 1.66186227 |
| 18 | IRAK3 | 1.56989965 |
| 19 | PBK | 1.50052061 |
| 20 | SRPK1 | 1.39379216 |
| 21 | BCR | 1.36666706 |
| 22 | EIF2AK1 | 1.31267201 |
| 23 | BCKDK | 1.27107535 |
| 24 | ADRBK2 | 1.23269747 |
| 25 | NUAK1 | 1.16339840 |
| 26 | DAPK3 | 1.15518533 |
| 27 | WNK4 | 1.14280182 |
| 28 | MAP3K11 | 1.08042675 |
| 29 | PIM2 | 1.06836015 |
| 30 | PLK3 | 1.06543138 |
| 31 | SCYL2 | 1.02357204 |
| 32 | LMTK2 | 1.01825000 |
| 33 | RPS6KA5 | 0.99577420 |
| 34 | GRK1 | 0.96699973 |
| 35 | EIF2AK3 | 0.96103770 |
| 36 | CSNK1A1L | 0.96055267 |
| 37 | CDK8 | 0.93587879 |
| 38 | CSNK1G3 | 0.92945695 |
| 39 | TESK2 | 0.91211906 |
| 40 | STK39 | 0.84715213 |
| 41 | CSNK1G2 | 0.84225335 |
| 42 | AURKA | 0.84052336 |
| 43 | PLK2 | 0.83874683 |
| 44 | BRSK1 | 0.82259935 |
| 45 | FGFR1 | 0.78613073 |
| 46 | CAMKK2 | 0.78274653 |
| 47 | LIMK1 | 0.77850360 |
| 48 | CSNK1G1 | 0.77671413 |
| 49 | DYRK2 | 0.73342526 |
| 50 | DAPK1 | 0.73019487 |
| 51 | AURKB | 0.71809400 |
| 52 | PDK2 | 0.70707160 |
| 53 | PAK4 | 0.68903047 |
| 54 | STK16 | 0.68193675 |
| 55 | ALK | 0.67693887 |
| 56 | MAP3K6 | 0.64140415 |
| 57 | MAP2K7 | 0.57089723 |
| 58 | GRK6 | 0.55254906 |
| 59 | TXK | 0.54412554 |
| 60 | TRIM28 | 0.53399073 |
| 61 | TAOK1 | 0.51102591 |
| 62 | ARAF | 0.50911311 |
| 63 | GRK5 | 0.50528392 |
| 64 | OXSR1 | 0.50008246 |
| 65 | PLK1 | 0.49610966 |
| 66 | BLK | 0.48640006 |
| 67 | IKBKB | 0.46878632 |
| 68 | FRK | 0.45600976 |
| 69 | PHKG2 | 0.44930096 |
| 70 | PHKG1 | 0.44930096 |
| 71 | AKT2 | 0.44108893 |
| 72 | RPS6KB2 | 0.43444212 |
| 73 | PRKCI | 0.41809134 |
| 74 | CSNK2A2 | 0.40895789 |
| 75 | CSNK2A1 | 0.40647987 |
| 76 | CLK1 | 0.38524138 |
| 77 | MAPKAPK3 | 0.37443492 |
| 78 | PRKCQ | 0.36326013 |
| 79 | MAP3K12 | 0.35787323 |
| 80 | TESK1 | 0.34945854 |
| 81 | ATR | 0.34869008 |
| 82 | PKN1 | 0.32782846 |
| 83 | PIM1 | 0.32514850 |
| 84 | IKBKE | 0.32486529 |
| 85 | MST1R | 0.28180159 |
| 86 | CHEK1 | 0.26507367 |
| 87 | NME2 | 0.25459414 |
| 88 | STK4 | 0.23805010 |
| 89 | ILK | 0.23473113 |
| 90 | MYLK | 0.21643212 |
| 91 | PLK4 | 0.21432389 |
| 92 | CASK | 0.21226043 |
| 93 | EIF2AK2 | 0.21174844 |
| 94 | FER | 0.20679406 |
| 95 | OBSCN | 0.20632912 |
| 96 | GRK7 | 0.20609894 |
| 97 | CDK9 | 0.20053001 |
| 98 | PASK | 0.19453918 |
| 99 | PRKCG | 0.18781366 |
| 100 | TAOK3 | 0.18509394 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.42328502 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.88811512 |
| 3 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.81357412 |
| 4 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.78013999 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.50944590 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.45858667 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.25798886 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.25321871 |
| 9 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.19736857 |
| 10 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.13674853 |
| 11 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.09498558 |
| 12 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.08622688 |
| 13 | Protein export_Homo sapiens_hsa03060 | 2.07553109 |
| 14 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.07001856 |
| 15 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.95954390 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.89110051 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.85923106 |
| 18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.78876655 |
| 19 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.74719385 |
| 20 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.70664826 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.69258489 |
| 22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.61357935 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.61046928 |
| 24 | Peroxisome_Homo sapiens_hsa04146 | 1.60331561 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.54730876 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.45371280 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.44534016 |
| 28 | RNA transport_Homo sapiens_hsa03013 | 1.44106383 |
| 29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.42307759 |
| 30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.42288077 |
| 31 | Alzheimers disease_Homo sapiens_hsa05010 | 1.40094430 |
| 32 | Base excision repair_Homo sapiens_hsa03410 | 1.36071945 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.35455265 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33796661 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 1.32012273 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.29484378 |
| 37 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.29180213 |
| 38 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.27392811 |
| 39 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.26459776 |
| 40 | Alcoholism_Homo sapiens_hsa05034 | 1.24945122 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.21993395 |
| 42 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.18411462 |
| 43 | Sulfur relay system_Homo sapiens_hsa04122 | 1.17279932 |
| 44 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.12545858 |
| 45 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.11718386 |
| 46 | Homologous recombination_Homo sapiens_hsa03440 | 1.08838175 |
| 47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.07612113 |
| 48 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.06994692 |
| 49 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.00877526 |
| 50 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.98028384 |
| 51 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.96999992 |
| 52 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.95984175 |
| 53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.94301877 |
| 54 | Ribosome_Homo sapiens_hsa03010 | 0.94274242 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.92858076 |
| 56 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.91208399 |
| 57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.91038295 |
| 58 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.90959997 |
| 59 | Purine metabolism_Homo sapiens_hsa00230 | 0.90649871 |
| 60 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.84939325 |
| 61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.82387091 |
| 62 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.81954124 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.79699312 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.77907594 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.77894660 |
| 66 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.77072534 |
| 67 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.76775216 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.75071469 |
| 69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.74534947 |
| 70 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.74345575 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71997490 |
| 72 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.71784162 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71430281 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.71119349 |
| 75 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70481413 |
| 76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.70063885 |
| 77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.66607944 |
| 78 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66379684 |
| 79 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.64715911 |
| 80 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.60697436 |
| 81 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.55887232 |
| 82 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.52034707 |
| 83 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.48268644 |
| 84 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.45565945 |
| 85 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.43333886 |
| 86 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.43063259 |
| 87 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.42468036 |
| 88 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.39115872 |
| 89 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.37685092 |
| 90 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37380129 |
| 91 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.36672881 |
| 92 | Cell cycle_Homo sapiens_hsa04110 | 0.35071429 |
| 93 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.34458110 |
| 94 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.33383554 |
| 95 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.27423325 |
| 96 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.27010835 |
| 97 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.26997052 |
| 98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26708904 |
| 99 | Prion diseases_Homo sapiens_hsa05020 | 0.24242173 |
| 100 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.23999866 |

