

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | growth hormone receptor signaling pathway (GO:0060396) | 9.63355215 |
| 2 | cellular response to growth hormone stimulus (GO:0071378) | 8.66312471 |
| 3 | sequestering of actin monomers (GO:0042989) | 8.21542905 |
| 4 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 7.59602057 |
| 5 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 6.57330766 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.99490792 |
| 7 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 5.86677103 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 5.85177887 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.85177887 |
| 10 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 5.70758298 |
| 11 | neurotransmitter catabolic process (GO:0042135) | 5.03016577 |
| 12 | positive regulation of heat generation (GO:0031652) | 4.80298323 |
| 13 | response to growth hormone (GO:0060416) | 4.79225110 |
| 14 | positive regulation of receptor internalization (GO:0002092) | 4.42313626 |
| 15 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 4.07548169 |
| 16 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 4.04520819 |
| 17 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.99919621 |
| 18 | proteasome assembly (GO:0043248) | 3.95919009 |
| 19 | T-helper 1 type immune response (GO:0042088) | 3.91879291 |
| 20 | positive regulation of T cell cytokine production (GO:0002726) | 3.88440965 |
| 21 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.84585181 |
| 22 | activated T cell proliferation (GO:0050798) | 3.73944577 |
| 23 | primitive streak formation (GO:0090009) | 3.70611659 |
| 24 | thalamus development (GO:0021794) | 3.69760124 |
| 25 | gonadal mesoderm development (GO:0007506) | 3.66389302 |
| 26 | regulation of fever generation (GO:0031620) | 3.66113124 |
| 27 | positive regulation of bone resorption (GO:0045780) | 3.61870295 |
| 28 | positive regulation of bone remodeling (GO:0046852) | 3.61870295 |
| 29 | regulation of heat generation (GO:0031650) | 3.60789808 |
| 30 | positive regulation of tyrosine phosphorylation of Stat3 protein (GO:0042517) | 3.58133476 |
| 31 | dopaminergic neuron differentiation (GO:0071542) | 3.54122604 |
| 32 | actin nucleation (GO:0045010) | 3.53057199 |
| 33 | replication fork processing (GO:0031297) | 3.43438582 |
| 34 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.40432616 |
| 35 | positive regulation of prostaglandin secretion (GO:0032308) | 3.39813827 |
| 36 | oxidative phosphorylation (GO:0006119) | 3.39157459 |
| 37 | purine nucleotide salvage (GO:0032261) | 3.38869814 |
| 38 | toxin transport (GO:1901998) | 3.36539248 |
| 39 | GPI anchor biosynthetic process (GO:0006506) | 3.36209172 |
| 40 | regulation of dopamine metabolic process (GO:0042053) | 3.33343034 |
| 41 | regulation of catecholamine metabolic process (GO:0042069) | 3.33343034 |
| 42 | regulation of receptor internalization (GO:0002090) | 3.30977044 |
| 43 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.29531100 |
| 44 | protein polyglutamylation (GO:0018095) | 3.25634584 |
| 45 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.24676372 |
| 46 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.24676372 |
| 47 | germ cell migration (GO:0008354) | 3.21244402 |
| 48 | GPI anchor metabolic process (GO:0006505) | 3.20762912 |
| 49 | mannosylation (GO:0097502) | 3.19917987 |
| 50 | regulation of prostaglandin secretion (GO:0032306) | 3.15840680 |
| 51 | regulation of tyrosine phosphorylation of Stat3 protein (GO:0042516) | 3.09948650 |
| 52 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 3.09284220 |
| 53 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.08177477 |
| 54 | regulation of immunoglobulin secretion (GO:0051023) | 3.07221074 |
| 55 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.04007782 |
| 56 | negative regulation of telomere maintenance (GO:0032205) | 2.91334618 |
| 57 | purine nucleobase biosynthetic process (GO:0009113) | 2.90158856 |
| 58 | electron transport chain (GO:0022900) | 2.89938969 |
| 59 | respiratory electron transport chain (GO:0022904) | 2.89609187 |
| 60 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.89406260 |
| 61 | hydrogen ion transmembrane transport (GO:1902600) | 2.89182941 |
| 62 | estrogen biosynthetic process (GO:0006703) | 2.88530735 |
| 63 | tachykinin receptor signaling pathway (GO:0007217) | 2.76381786 |
| 64 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.75935654 |
| 65 | regulation of uterine smooth muscle contraction (GO:0070472) | 2.74217840 |
| 66 | positive regulation of protein homodimerization activity (GO:0090073) | 2.74030942 |
| 67 | protein complex biogenesis (GO:0070271) | 2.64789527 |
| 68 | endoderm formation (GO:0001706) | 2.64391041 |
| 69 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.64194655 |
| 70 | anatomical structure maturation (GO:0071695) | 2.62958147 |
| 71 | ATP biosynthetic process (GO:0006754) | 2.62764582 |
| 72 | righting reflex (GO:0060013) | 2.61733339 |
| 73 | signal peptide processing (GO:0006465) | 2.58871417 |
| 74 | otic vesicle formation (GO:0030916) | 2.58491782 |
| 75 | signal transduction involved in regulation of gene expression (GO:0023019) | 2.56518098 |
| 76 | translational termination (GO:0006415) | 2.55487980 |
| 77 | positive regulation of icosanoid secretion (GO:0032305) | 2.52772520 |
| 78 | chemosensory behavior (GO:0007635) | 2.51536339 |
| 79 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 2.47952922 |
| 80 | proton transport (GO:0015992) | 2.46235210 |
| 81 | viral transcription (GO:0019083) | 2.46000332 |
| 82 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.45780096 |
| 83 | cellular ketone body metabolic process (GO:0046950) | 2.44998829 |
| 84 | hydrogen transport (GO:0006818) | 2.44822042 |
| 85 | cotranslational protein targeting to membrane (GO:0006613) | 2.44558231 |
| 86 | regulation of icosanoid secretion (GO:0032303) | 2.43485985 |
| 87 | protein targeting to ER (GO:0045047) | 2.40457671 |
| 88 | microglial cell activation (GO:0001774) | 2.40264256 |
| 89 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 2.39981389 |
| 90 | nucleobase biosynthetic process (GO:0046112) | 2.39507551 |
| 91 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.39363621 |
| 92 | NADH dehydrogenase complex assembly (GO:0010257) | 2.39363621 |
| 93 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.39363621 |
| 94 | platelet dense granule organization (GO:0060155) | 2.38059727 |
| 95 | dendrite morphogenesis (GO:0048813) | 2.37994527 |
| 96 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.36394478 |
| 97 | rRNA modification (GO:0000154) | 2.34312502 |
| 98 | regulation of memory T cell differentiation (GO:0043380) | 2.34296332 |
| 99 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.32762004 |
| 100 | regulation of activation of Janus kinase activity (GO:0010533) | 12.1221951 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.39182444 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.49921441 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.34477122 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.08454593 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.82143314 |
| 6 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.60134211 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.52902209 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.50463385 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.40786227 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.16485678 |
| 11 | EWS_26573619_Chip-Seq_HEK293_Human | 2.14749522 |
| 12 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.13139763 |
| 13 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.11345752 |
| 14 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.09757361 |
| 15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.07349600 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.05353419 |
| 17 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.02661658 |
| 18 | FUS_26573619_Chip-Seq_HEK293_Human | 1.99418242 |
| 19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.88624374 |
| 20 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.86959525 |
| 21 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.82731063 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.77563773 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.72801278 |
| 24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.71490338 |
| 25 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.70770550 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.66797666 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.64462389 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.61514736 |
| 29 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.59494949 |
| 30 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.58926777 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56530704 |
| 32 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.55714910 |
| 33 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.55656787 |
| 34 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.53485349 |
| 35 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.52695698 |
| 36 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.49619565 |
| 37 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.45449551 |
| 38 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.44658876 |
| 39 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.43773867 |
| 40 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42992769 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.42842529 |
| 42 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.42842529 |
| 43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.42062461 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.41960667 |
| 45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.41200597 |
| 46 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.40259113 |
| 47 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.38349422 |
| 48 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.38031151 |
| 49 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.37183689 |
| 50 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.32381121 |
| 51 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.32098054 |
| 52 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.29193461 |
| 53 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.28032711 |
| 54 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25749062 |
| 55 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.25704237 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.25096010 |
| 57 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.24858631 |
| 58 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.24765915 |
| 59 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.18234104 |
| 60 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.17812796 |
| 61 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.17503374 |
| 62 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.16512945 |
| 63 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.16079609 |
| 64 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15187238 |
| 65 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.13488116 |
| 66 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.13448823 |
| 67 | AR_25329375_ChIP-Seq_VCAP_Human | 1.13365487 |
| 68 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.13240708 |
| 69 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.12447578 |
| 70 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.11631032 |
| 71 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.11614673 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.11533008 |
| 73 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.10410972 |
| 74 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.09375899 |
| 75 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.08714810 |
| 76 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.08509131 |
| 77 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.07817981 |
| 78 | AR_20517297_ChIP-Seq_VCAP_Human | 1.07642162 |
| 79 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.05737385 |
| 80 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05413171 |
| 81 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.04950490 |
| 82 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.04550758 |
| 83 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02676480 |
| 84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.02005225 |
| 85 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.99038290 |
| 86 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.96849382 |
| 87 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.96797978 |
| 88 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.96455056 |
| 89 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96268844 |
| 90 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.95586588 |
| 91 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.95367968 |
| 92 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.94589590 |
| 93 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.94014473 |
| 94 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.92752841 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.92453258 |
| 96 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92414173 |
| 97 | ERA_21632823_ChIP-Seq_H3396_Human | 0.92190066 |
| 98 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.91540972 |
| 99 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.91152300 |
| 100 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90535135 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005451_abnormal_body_composition | 4.10533693 |
| 2 | MP0004147_increased_porphyrin_level | 3.56054542 |
| 3 | MP0009840_abnormal_foam_cell | 3.43193940 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.32520689 |
| 5 | MP0002234_abnormal_pharynx_morphology | 3.28341841 |
| 6 | MP0003880_abnormal_central_pattern | 3.22436690 |
| 7 | MP0005394_taste/olfaction_phenotype | 3.20851443 |
| 8 | MP0005499_abnormal_olfactory_system | 3.20851443 |
| 9 | MP0008789_abnormal_olfactory_epithelium | 3.15769994 |
| 10 | MP0003011_delayed_dark_adaptation | 2.67640127 |
| 11 | MP0001293_anophthalmia | 2.53066854 |
| 12 | MP0003890_abnormal_embryonic-extraembry | 2.39180030 |
| 13 | MP0001529_abnormal_vocalization | 2.37864989 |
| 14 | MP0000049_abnormal_middle_ear | 2.28092722 |
| 15 | MP0002102_abnormal_ear_morphology | 2.08356866 |
| 16 | MP0001905_abnormal_dopamine_level | 2.00740692 |
| 17 | MP0004885_abnormal_endolymph | 1.96059584 |
| 18 | MP0010030_abnormal_orbit_morphology | 1.94929524 |
| 19 | MP0002249_abnormal_larynx_morphology | 1.94211842 |
| 20 | MP0005423_abnormal_somatic_nervous | 1.89004579 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 1.81500840 |
| 22 | MP0004142_abnormal_muscle_tone | 1.78608555 |
| 23 | MP0009250_abnormal_appendicular_skeleto | 1.74819437 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.68876763 |
| 25 | MP0002653_abnormal_ependyma_morphology | 1.68276518 |
| 26 | MP0003724_increased_susceptibility_to | 1.62268800 |
| 27 | MP0003191_abnormal_cellular_cholesterol | 1.60075346 |
| 28 | MP0004133_heterotaxia | 1.57120878 |
| 29 | MP0001485_abnormal_pinna_reflex | 1.53490020 |
| 30 | MP0002282_abnormal_trachea_morphology | 1.50198608 |
| 31 | MP0003195_calcinosis | 1.47067494 |
| 32 | MP0002277_abnormal_respiratory_mucosa | 1.46302261 |
| 33 | MP0005377_hearing/vestibular/ear_phenot | 1.39584170 |
| 34 | MP0003878_abnormal_ear_physiology | 1.39584170 |
| 35 | MP0003937_abnormal_limbs/digits/tail_de | 1.34834523 |
| 36 | MP0002095_abnormal_skin_pigmentation | 1.31288881 |
| 37 | MP0002928_abnormal_bile_duct | 1.28683943 |
| 38 | MP0000538_abnormal_urinary_bladder | 1.27638152 |
| 39 | MP0009053_abnormal_anal_canal | 1.23546958 |
| 40 | MP0002148_abnormal_hypersensitivity_rea | 1.22167976 |
| 41 | MP0008961_abnormal_basal_metabolism | 1.21804908 |
| 42 | MP0002139_abnormal_hepatobiliary_system | 1.20038649 |
| 43 | MP0004782_abnormal_surfactant_physiolog | 1.19982046 |
| 44 | MP0000778_abnormal_nervous_system | 1.19585135 |
| 45 | MP0002233_abnormal_nose_morphology | 1.18500777 |
| 46 | MP0008995_early_reproductive_senescence | 1.15666803 |
| 47 | MP0003787_abnormal_imprinting | 1.10536357 |
| 48 | MP0005671_abnormal_response_to | 1.10184485 |
| 49 | MP0002405_respiratory_system_inflammati | 1.09679049 |
| 50 | MP0002160_abnormal_reproductive_system | 1.01774222 |
| 51 | MP0004043_abnormal_pH_regulation | 0.99689399 |
| 52 | MP0000631_abnormal_neuroendocrine_gland | 0.98870592 |
| 53 | MP0005187_abnormal_penis_morphology | 0.96654623 |
| 54 | MP0001984_abnormal_olfaction | 0.95771650 |
| 55 | MP0005391_vision/eye_phenotype | 0.95348418 |
| 56 | MP0000647_abnormal_sebaceous_gland | 0.92907365 |
| 57 | MP0002092_abnormal_eye_morphology | 0.91682269 |
| 58 | MP0009785_altered_susceptibility_to | 0.91228338 |
| 59 | MP0000026_abnormal_inner_ear | 0.90570412 |
| 60 | MP0003119_abnormal_digestive_system | 0.89679326 |
| 61 | MP0003828_pulmonary_edema | 0.89628177 |
| 62 | MP0005253_abnormal_eye_physiology | 0.88421331 |
| 63 | MP0002723_abnormal_immune_serum | 0.85168983 |
| 64 | MP0001963_abnormal_hearing_physiology | 0.84286106 |
| 65 | MP0000163_abnormal_cartilage_morphology | 0.84199695 |
| 66 | MP0003938_abnormal_ear_development | 0.84005354 |
| 67 | MP0002638_abnormal_pupillary_reflex | 0.83578287 |
| 68 | MP0002177_abnormal_outer_ear | 0.82511649 |
| 69 | MP0005410_abnormal_fertilization | 0.82493637 |
| 70 | MP0001286_abnormal_eye_development | 0.81428848 |
| 71 | MP0002933_joint_inflammation | 0.80176459 |
| 72 | MP0003436_decreased_susceptibility_to | 0.79680454 |
| 73 | MP0009764_decreased_sensitivity_to | 0.78239451 |
| 74 | MP0005551_abnormal_eye_electrophysiolog | 0.77176996 |
| 75 | MP0001800_abnormal_humoral_immune | 0.74301716 |
| 76 | MP0001188_hyperpigmentation | 0.73453528 |
| 77 | MP0002067_abnormal_sensory_capabilities | 0.72840152 |
| 78 | MP0000566_synostosis | 0.72552727 |
| 79 | MP0009379_abnormal_foot_pigmentation | 0.72322659 |
| 80 | MP0005389_reproductive_system_phenotype | 0.71902859 |
| 81 | MP0002752_abnormal_somatic_nervous | 0.70677745 |
| 82 | MP0002272_abnormal_nervous_system | 0.70618145 |
| 83 | MP0002938_white_spotting | 0.69094754 |
| 84 | MP0002116_abnormal_craniofacial_bone | 0.68669908 |
| 85 | MP0009697_abnormal_copulation | 0.68523270 |
| 86 | MP0008932_abnormal_embryonic_tissue | 0.66235717 |
| 87 | MP0003121_genomic_imprinting | 0.64092012 |
| 88 | MP0008872_abnormal_physiological_respon | 0.63917255 |
| 89 | MP0000230_abnormal_systemic_arterial | 0.62182855 |
| 90 | MP0001177_atelectasis | 0.62142833 |
| 91 | MP0002109_abnormal_limb_morphology | 0.61876945 |
| 92 | MP0004130_abnormal_muscle_cell | 0.61560107 |
| 93 | MP0005195_abnormal_posterior_eye | 0.61281692 |
| 94 | MP0002452_abnormal_antigen_presenting | 0.61070422 |
| 95 | MP0006072_abnormal_retinal_apoptosis | 0.60142678 |
| 96 | MP0002184_abnormal_innervation | 0.59697845 |
| 97 | MP0002697_abnormal_eye_size | 0.58992891 |
| 98 | MP0003385_abnormal_body_wall | 0.58756370 |
| 99 | MP0003122_maternal_imprinting | 0.58259243 |
| 100 | MP0000569_abnormal_digit_pigmentation | 0.57431730 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B lymphocytopenia (HP:0010976) | 4.08960793 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 3.94379494 |
| 3 | Type II lissencephaly (HP:0007260) | 3.90073924 |
| 4 | Abnormality of B cell number (HP:0010975) | 3.88625557 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.74040302 |
| 6 | Growth hormone deficiency (HP:0000824) | 3.57752373 |
| 7 | Retinal dysplasia (HP:0007973) | 3.57468117 |
| 8 | Pancreatic fibrosis (HP:0100732) | 3.28366674 |
| 9 | Cerebellar dysplasia (HP:0007033) | 3.28127603 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.26240726 |
| 11 | Pancreatic cysts (HP:0001737) | 3.22712278 |
| 12 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.21587019 |
| 13 | Renal cortical cysts (HP:0000803) | 3.20824134 |
| 14 | Severe short stature (HP:0003510) | 3.07824186 |
| 15 | Limb dystonia (HP:0002451) | 2.94281524 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 2.92126446 |
| 17 | Abnormality of the renal cortex (HP:0011035) | 2.91853330 |
| 18 | Glycosuria (HP:0003076) | 2.76746441 |
| 19 | Abnormality of urine glucose concentration (HP:0011016) | 2.76746441 |
| 20 | Potter facies (HP:0002009) | 2.71899667 |
| 21 | Facial shape deformation (HP:0011334) | 2.71899667 |
| 22 | Congenital, generalized hypertrichosis (HP:0004540) | 2.71742910 |
| 23 | Abolished electroretinogram (ERG) (HP:0000550) | 2.71668836 |
| 24 | True hermaphroditism (HP:0010459) | 2.68332468 |
| 25 | Enlarged kidneys (HP:0000105) | 2.66715522 |
| 26 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.65614106 |
| 27 | Abnormal number of erythroid precursors (HP:0012131) | 2.62310390 |
| 28 | Bile duct proliferation (HP:0001408) | 2.61787653 |
| 29 | Abnormal biliary tract physiology (HP:0012439) | 2.61787653 |
| 30 | IgM deficiency (HP:0002850) | 2.52486575 |
| 31 | Increased intramyocellular lipid droplets (HP:0012240) | 2.51714633 |
| 32 | Exertional dyspnea (HP:0002875) | 2.44235537 |
| 33 | Pancytopenia (HP:0001876) | 2.41200912 |
| 34 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.39829630 |
| 35 | Abnormal protein glycosylation (HP:0012346) | 2.39829630 |
| 36 | Abnormal glycosylation (HP:0012345) | 2.39829630 |
| 37 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.39829630 |
| 38 | Male pseudohermaphroditism (HP:0000037) | 2.36511024 |
| 39 | Lissencephaly (HP:0001339) | 2.36082875 |
| 40 | Adactyly (HP:0009776) | 2.35218860 |
| 41 | Disproportionate short-trunk short stature (HP:0003521) | 2.34283902 |
| 42 | Severe combined immunodeficiency (HP:0004430) | 2.33541963 |
| 43 | Mitochondrial inheritance (HP:0001427) | 2.30720340 |
| 44 | Nephronophthisis (HP:0000090) | 2.28106799 |
| 45 | Abnormality of the renal medulla (HP:0100957) | 2.28023514 |
| 46 | Duplicated collecting system (HP:0000081) | 2.23914262 |
| 47 | Chronic hepatic failure (HP:0100626) | 2.23609945 |
| 48 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.22673045 |
| 49 | Supernumerary spleens (HP:0009799) | 2.22664323 |
| 50 | Acute necrotizing encephalopathy (HP:0006965) | 2.21286393 |
| 51 | IgG deficiency (HP:0004315) | 2.20946493 |
| 52 | Recurrent bronchitis (HP:0002837) | 2.19956477 |
| 53 | Increased density of long bones (HP:0006392) | 2.16036509 |
| 54 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.13095745 |
| 55 | Increased CSF lactate (HP:0002490) | 2.12333262 |
| 56 | Attenuation of retinal blood vessels (HP:0007843) | 2.11676388 |
| 57 | Abnormality of the renal collecting system (HP:0004742) | 2.11381168 |
| 58 | Hyperphosphaturia (HP:0003109) | 2.08107784 |
| 59 | Increased muscle lipid content (HP:0009058) | 2.07467544 |
| 60 | Molar tooth sign on MRI (HP:0002419) | 2.07339166 |
| 61 | Abnormality of midbrain morphology (HP:0002418) | 2.07339166 |
| 62 | Polymicrogyria (HP:0002126) | 2.06725281 |
| 63 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.06593177 |
| 64 | Type I transferrin isoform profile (HP:0003642) | 2.01130302 |
| 65 | Generalized aminoaciduria (HP:0002909) | 2.00186406 |
| 66 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.96530609 |
| 67 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.96530609 |
| 68 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.94414180 |
| 69 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.93425487 |
| 70 | Premature ovarian failure (HP:0008209) | 1.93254798 |
| 71 | Acute encephalopathy (HP:0006846) | 1.93011077 |
| 72 | T lymphocytopenia (HP:0005403) | 1.92713597 |
| 73 | Anencephaly (HP:0002323) | 1.92579617 |
| 74 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.92527251 |
| 75 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.91790899 |
| 76 | Macrocytic anemia (HP:0001972) | 1.91405115 |
| 77 | Abnormality of renal resorption (HP:0011038) | 1.90999193 |
| 78 | Progressive macrocephaly (HP:0004481) | 1.88794898 |
| 79 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.88238226 |
| 80 | Bell-shaped thorax (HP:0001591) | 1.87996874 |
| 81 | Genetic anticipation (HP:0003743) | 1.86886706 |
| 82 | Thyroiditis (HP:0100646) | 1.86168250 |
| 83 | Respiratory difficulties (HP:0002880) | 1.85895288 |
| 84 | Agitation (HP:0000713) | 1.83659994 |
| 85 | Large for gestational age (HP:0001520) | 1.83151117 |
| 86 | Type 2 muscle fiber atrophy (HP:0003554) | 1.82590507 |
| 87 | Depressed nasal ridge (HP:0000457) | 1.81151414 |
| 88 | Constricted visual fields (HP:0001133) | 1.80918628 |
| 89 | Pallor (HP:0000980) | 1.80843064 |
| 90 | Long nose (HP:0003189) | 1.80249191 |
| 91 | Congenital hepatic fibrosis (HP:0002612) | 1.78543133 |
| 92 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.77745183 |
| 93 | Abnormality of the 2nd finger (HP:0004100) | 1.77533615 |
| 94 | Oligohydramnios (HP:0001562) | 1.77325800 |
| 95 | Hyperglycinemia (HP:0002154) | 1.75876315 |
| 96 | Persistence of primary teeth (HP:0006335) | 1.74564327 |
| 97 | Abnormality of DNA repair (HP:0003254) | 1.74508547 |
| 98 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.74105611 |
| 99 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.74105611 |
| 100 | Sclerocornea (HP:0000647) | 1.73775464 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.01542624 |
| 2 | ACVR1B | 3.78167509 |
| 3 | BCKDK | 3.73610202 |
| 4 | BLK | 3.68877596 |
| 5 | CDC7 | 2.38779474 |
| 6 | BMPR1B | 2.34003725 |
| 7 | GRK6 | 2.27569346 |
| 8 | MAP4K1 | 2.09089053 |
| 9 | TLK1 | 1.95570974 |
| 10 | TAOK3 | 1.78886151 |
| 11 | ZAK | 1.77543377 |
| 12 | TXK | 1.74230148 |
| 13 | MAP3K12 | 1.73183871 |
| 14 | TESK1 | 1.57813382 |
| 15 | FES | 1.54405023 |
| 16 | FLT3 | 1.52513030 |
| 17 | PASK | 1.47509873 |
| 18 | PLK4 | 1.40029157 |
| 19 | MAP3K11 | 1.37119931 |
| 20 | ADRBK1 | 1.37107292 |
| 21 | TEC | 1.35929988 |
| 22 | ITK | 1.33128588 |
| 23 | PIM1 | 1.33028273 |
| 24 | KDR | 1.30547695 |
| 25 | CDK19 | 1.29430023 |
| 26 | MATK | 1.28047743 |
| 27 | MAP2K2 | 1.26785978 |
| 28 | CDK8 | 1.26548972 |
| 29 | KIT | 1.21224341 |
| 30 | INSRR | 1.18111289 |
| 31 | ADRBK2 | 1.15346052 |
| 32 | CSK | 1.11131908 |
| 33 | TGFBR1 | 1.06260432 |
| 34 | GRK7 | 1.05748245 |
| 35 | PLK2 | 1.04838737 |
| 36 | PAK3 | 1.02734331 |
| 37 | WNK4 | 1.02524404 |
| 38 | FRK | 1.00165018 |
| 39 | SYK | 0.99955533 |
| 40 | MAPK13 | 0.99939896 |
| 41 | EIF2AK1 | 0.99593218 |
| 42 | CSF1R | 0.97750707 |
| 43 | EPHB2 | 0.97539552 |
| 44 | PIM2 | 0.96825501 |
| 45 | STK11 | 0.95249640 |
| 46 | ARAF | 0.92214188 |
| 47 | WNK3 | 0.89375523 |
| 48 | DYRK2 | 0.87256110 |
| 49 | EPHA4 | 0.81927025 |
| 50 | NME1 | 0.75343741 |
| 51 | SRPK1 | 0.71843643 |
| 52 | PINK1 | 0.71600137 |
| 53 | LYN | 0.71598271 |
| 54 | CSNK1G1 | 0.70992403 |
| 55 | ERBB3 | 0.69845463 |
| 56 | AKT3 | 0.69708257 |
| 57 | OXSR1 | 0.68860169 |
| 58 | JAK3 | 0.67708876 |
| 59 | PIK3CA | 0.66298522 |
| 60 | ERBB2 | 0.65191839 |
| 61 | PTK2B | 0.61624355 |
| 62 | LIMK1 | 0.60826834 |
| 63 | STK4 | 0.60736600 |
| 64 | TRIM28 | 0.60668196 |
| 65 | LCK | 0.59548969 |
| 66 | PNCK | 0.59402489 |
| 67 | TAOK1 | 0.59282414 |
| 68 | MAP3K13 | 0.59107945 |
| 69 | MAP3K1 | 0.57951768 |
| 70 | CAMK1G | 0.57665041 |
| 71 | VRK1 | 0.57074776 |
| 72 | CSNK1G2 | 0.56894244 |
| 73 | ZAP70 | 0.54855716 |
| 74 | FER | 0.54801809 |
| 75 | LRRK2 | 0.53770219 |
| 76 | TNIK | 0.52285469 |
| 77 | MAPK15 | 0.50909341 |
| 78 | PRKACB | 0.50829928 |
| 79 | PKN1 | 0.50718843 |
| 80 | MAP4K2 | 0.50673132 |
| 81 | STK10 | 0.50445285 |
| 82 | HIPK2 | 0.50169769 |
| 83 | MAP2K1 | 0.49088940 |
| 84 | RAF1 | 0.48011521 |
| 85 | INSR | 0.47154276 |
| 86 | FYN | 0.45593714 |
| 87 | PIK3CG | 0.42562249 |
| 88 | PRKCE | 0.42106744 |
| 89 | CAMK1D | 0.41419244 |
| 90 | TIE1 | 0.41199613 |
| 91 | CSNK1A1 | 0.40846105 |
| 92 | RPS6KA5 | 0.39670222 |
| 93 | CSNK2A2 | 0.39435911 |
| 94 | BTK | 0.38537215 |
| 95 | PRKCQ | 0.36220350 |
| 96 | CSNK2A1 | 0.35118124 |
| 97 | SGK494 | 0.34730471 |
| 98 | SGK223 | 0.34730471 |
| 99 | EIF2AK2 | 0.32160158 |
| 100 | CAMKK2 | 0.31615105 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 4.66254678 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.62593893 |
| 3 | Caffeine metabolism_Homo sapiens_hsa00232 | 3.59718680 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.26003557 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.91630519 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.81194084 |
| 7 | Proteasome_Homo sapiens_hsa03050 | 2.72039863 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.70025175 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.53152178 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.51101892 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.33956644 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.22745702 |
| 13 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.16278824 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.04420277 |
| 15 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.04061976 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.02547207 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.89952431 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.80568544 |
| 19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.74891306 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.72297103 |
| 21 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.68735510 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.61161163 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.50404903 |
| 24 | Peroxisome_Homo sapiens_hsa04146 | 1.43725311 |
| 25 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.33203769 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.29742556 |
| 27 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.27034229 |
| 28 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.20670087 |
| 29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.20363400 |
| 30 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.18980432 |
| 31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.18076315 |
| 32 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.12303022 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.11811739 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.97034509 |
| 35 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.95813559 |
| 36 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.94596446 |
| 37 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.94149452 |
| 38 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.94074815 |
| 39 | Nicotine addiction_Homo sapiens_hsa05033 | 0.89505269 |
| 40 | Basal transcription factors_Homo sapiens_hsa03022 | 0.88521092 |
| 41 | RNA polymerase_Homo sapiens_hsa03020 | 0.88350832 |
| 42 | Phototransduction_Homo sapiens_hsa04744 | 0.87865408 |
| 43 | RNA degradation_Homo sapiens_hsa03018 | 0.86341752 |
| 44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82892041 |
| 45 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.82211143 |
| 46 | Morphine addiction_Homo sapiens_hsa05032 | 0.80057978 |
| 47 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.76692710 |
| 48 | Spliceosome_Homo sapiens_hsa03040 | 0.75939424 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.75862158 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70073502 |
| 51 | ABC transporters_Homo sapiens_hsa02010 | 0.70021852 |
| 52 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.68894357 |
| 53 | Taste transduction_Homo sapiens_hsa04742 | 0.67968134 |
| 54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.65556332 |
| 55 | GABAergic synapse_Homo sapiens_hsa04727 | 0.65323192 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.63456222 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63380546 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58433589 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.57990932 |
| 60 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.57756339 |
| 61 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.57498677 |
| 62 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56302966 |
| 63 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.51650127 |
| 64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50206409 |
| 65 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.50113168 |
| 66 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49317522 |
| 67 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.48979797 |
| 68 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.48287359 |
| 69 | Base excision repair_Homo sapiens_hsa03410 | 0.47093556 |
| 70 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.46156629 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45965429 |
| 72 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45840152 |
| 73 | Legionellosis_Homo sapiens_hsa05134 | 0.45528179 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45199831 |
| 75 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42095089 |
| 76 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.41466298 |
| 77 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41327582 |
| 78 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.40137953 |
| 79 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.39945471 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.39035048 |
| 81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.38003147 |
| 82 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.35708873 |
| 83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.35132068 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.33743308 |
| 85 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.33097533 |
| 86 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.30943837 |
| 87 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30070075 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28911522 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.26675564 |
| 90 | Asthma_Homo sapiens_hsa05310 | 0.26436474 |
| 91 | Circadian entrainment_Homo sapiens_hsa04713 | 0.25900397 |
| 92 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.24518180 |
| 93 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.23194803 |
| 94 | Circadian rhythm_Homo sapiens_hsa04710 | 0.22497854 |
| 95 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.22070510 |
| 96 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.21269662 |
| 97 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.20786168 |
| 98 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.20270546 |
| 99 | Allograft rejection_Homo sapiens_hsa05330 | 0.19852325 |
| 100 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.18892899 |

