VIL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1angiotensin maturation (GO:0002003)9.78026871
2regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)6.51450128
3vitamin A metabolic process (GO:0006776)6.24275114
4drug catabolic process (GO:0042737)5.86983261
5flavonoid metabolic process (GO:0009812)5.86180602
6UDP-N-acetylglucosamine metabolic process (GO:0006047)5.74949220
7epoxygenase P450 pathway (GO:0019373)5.49630637
8digestive system process (GO:0022600)5.49311163
9regulation of bile acid biosynthetic process (GO:0070857)5.45765287
103-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)5.43193041
11purine ribonucleoside bisphosphate metabolic process (GO:0034035)5.43193041
12regulation of guanylate cyclase activity (GO:0031282)5.26978591
13virion attachment to host cell (GO:0019062)5.23808387
14adhesion of symbiont to host cell (GO:0044650)5.23808387
15fat-soluble vitamin biosynthetic process (GO:0042362)5.16658249
16low-density lipoprotein particle remodeling (GO:0034374)5.13279351
17bundle of His cell to Purkinje myocyte communication (GO:0086069)5.12083079
18modified amino acid transport (GO:0072337)4.94147820
19high-density lipoprotein particle remodeling (GO:0034375)4.93217816
20intestinal epithelial cell development (GO:0060576)4.87623272
21plasma lipoprotein particle remodeling (GO:0034369)4.83586793
22protein-lipid complex remodeling (GO:0034368)4.83586793
23macromolecular complex remodeling (GO:0034367)4.83586793
24maintenance of gastrointestinal epithelium (GO:0030277)4.77523864
25sulfate transmembrane transport (GO:1902358)4.70467562
26plasma lipoprotein particle organization (GO:0071827)4.65716870
27peptide hormone processing (GO:0016486)4.60197850
28glucose 6-phosphate metabolic process (GO:0051156)4.57194914
29cellular glucuronidation (GO:0052695)4.53999469
30digestion (GO:0007586)4.52539073
31uronic acid metabolic process (GO:0006063)4.51022482
32glucuronate metabolic process (GO:0019585)4.51022482
33hormone catabolic process (GO:0042447)4.44189236
34reverse cholesterol transport (GO:0043691)4.43865006
35phospholipid efflux (GO:0033700)4.41526405
36protein-lipid complex subunit organization (GO:0071825)4.38394044
37bile acid and bile salt transport (GO:0015721)4.36706809
38lipoprotein metabolic process (GO:0042157)4.30372986
39drug transmembrane transport (GO:0006855)4.30058934
40sulfur compound transport (GO:0072348)4.24622666
41peptide catabolic process (GO:0043171)4.17236518
42drug transport (GO:0015893)4.16586833
43adhesion of symbiont to host (GO:0044406)4.14644174
44plasma lipoprotein particle assembly (GO:0034377)4.12239611
45positive regulation of lipoprotein lipase activity (GO:0051006)4.09996233
46positive regulation of triglyceride lipase activity (GO:0061365)4.09996233
47triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.06999152
48regulation of cholesterol homeostasis (GO:2000188)4.04478761
49protein-lipid complex assembly (GO:0065005)3.98449267
50vitamin transmembrane transport (GO:0035461)3.91282774
51regulation of cholesterol esterification (GO:0010872)3.90691295
52sulfate transport (GO:0008272)3.87298001
53urea cycle (GO:0000050)3.86439551
54bicarbonate transport (GO:0015701)3.84163707
55regulation of triglyceride catabolic process (GO:0010896)3.83650539
56positive regulation of guanylate cyclase activity (GO:0031284)3.82139592
57O-glycan processing (GO:0016266)3.80229524
58lipoprotein transport (GO:0042953)3.77741656
59sulfation (GO:0051923)3.74569121
60renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.74325073
61urea metabolic process (GO:0019627)3.71566100
62oligosaccharide catabolic process (GO:0009313)3.69866574
63epithelial structure maintenance (GO:0010669)3.67423805
64diacylglycerol metabolic process (GO:0046339)3.67328560
65exogenous drug catabolic process (GO:0042738)3.66813376
66fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.65669027
67transepithelial transport (GO:0070633)3.63459510
68very-low-density lipoprotein particle assembly (GO:0034379)3.60289473
69sterol homeostasis (GO:0055092)3.59710323
70cholesterol homeostasis (GO:0042632)3.58772418
71renal system process involved in regulation of blood volume (GO:0001977)3.54131887
72ethanol oxidation (GO:0006069)3.52913627
73transcytosis (GO:0045056)3.47239908
74sperm capacitation (GO:0048240)3.44707780
75cholesterol efflux (GO:0033344)3.44314370
76negative regulation of cholesterol transport (GO:0032375)3.42277952
77negative regulation of sterol transport (GO:0032372)3.42277952
78proline metabolic process (GO:0006560)3.41864512
79bile acid metabolic process (GO:0008206)3.39159976
80thyroid hormone metabolic process (GO:0042403)3.38523068
81glutamine family amino acid biosynthetic process (GO:0009084)3.37959210
82drinking behavior (GO:0042756)3.37194521
83membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.36671925
84nitrogen cycle metabolic process (GO:0071941)3.36621124
85regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.35797950
86endocrine process (GO:0050886)3.35797950
87regulation of systemic arterial blood pressure by hormone (GO:0001990)3.35797950
88regulation of cholesterol metabolic process (GO:0090181)3.35265273
89regulation of cellular extravasation (GO:0002691)3.32926734
90calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.30751208
91L-ascorbic acid metabolic process (GO:0019852)3.30250588
92positive regulation of lipid catabolic process (GO:0050996)3.29652958
93cholesterol transport (GO:0030301)3.28241677
94sterol transport (GO:0015918)3.28241677
95regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.26923863
96renal absorption (GO:0070293)3.26667748
97NADH metabolic process (GO:0006734)3.25302962
98antibacterial humoral response (GO:0019731)3.24857640
99phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.24304645
100antimicrobial humoral response (GO:0019730)3.21736145
101protein carboxylation (GO:0018214)3.21570983
102peptidyl-glutamic acid carboxylation (GO:0017187)3.21570983
103regulation of protein activation cascade (GO:2000257)3.20598775
104arginine metabolic process (GO:0006525)3.20200464
105regulation of cGMP biosynthetic process (GO:0030826)3.20130753
106purine nucleotide salvage (GO:0032261)3.19913012
107regulation of Golgi to plasma membrane protein transport (GO:0042996)3.17877062
108negative regulation of fibrinolysis (GO:0051918)3.16670984
109regulation of complement activation (GO:0030449)3.14922757
110phospholipid homeostasis (GO:0055091)3.13337995
111regulation of vitamin metabolic process (GO:0030656)3.11232262
112homocysteine metabolic process (GO:0050667)3.10895338
113lipid homeostasis (GO:0055088)3.10401181
114proline biosynthetic process (GO:0006561)3.08361302
115positive regulation of fatty acid biosynthetic process (GO:0045723)3.08222268
116negative regulation of digestive system process (GO:0060457)3.05220907
117drug metabolic process (GO:0017144)3.04979411
118response to hydroperoxide (GO:0033194)3.04272785
119positive regulation of steroid metabolic process (GO:0045940)3.03808316
120endocrine pancreas development (GO:0031018)3.03665029
121glycolipid catabolic process (GO:0019377)3.02892265
122regulation of extracellular matrix disassembly (GO:0010715)3.02289314
123glycosphingolipid catabolic process (GO:0046479)3.02031380
124glycerol metabolic process (GO:0006071)3.01864391
125sphingomyelin metabolic process (GO:0006684)3.00571184
126regulation of digestive system process (GO:0044058)2.99495808
127auditory receptor cell differentiation (GO:0042491)2.98516221
128negative regulation of keratinocyte proliferation (GO:0010839)2.97189922
129membrane repolarization during action potential (GO:0086011)2.96207538
130regulation of systemic arterial blood pressure (GO:0003073)2.94951022
131positive regulation of T cell differentiation in thymus (GO:0033089)2.94486612
132nucleotide-sugar biosynthetic process (GO:0009226)2.92633729
133cellular carbohydrate catabolic process (GO:0044275)2.89376106
134cytidine metabolic process (GO:0046087)2.89193166
135cytidine catabolic process (GO:0006216)2.89193166
136cytidine deamination (GO:0009972)2.89193166
137hepatocyte apoptotic process (GO:0097284)2.87684165
138hemidesmosome assembly (GO:0031581)2.85504224
139COPII vesicle coating (GO:0048208)2.85141344
140regulation of viral release from host cell (GO:1902186)2.84657087
141receptor guanylyl cyclase signaling pathway (GO:0007168)2.84648706
142thrombin receptor signaling pathway (GO:0070493)2.81536295
143fructose metabolic process (GO:0006000)2.79696014
144vitamin transport (GO:0051180)2.79563845
145nucleotide-sugar metabolic process (GO:0009225)2.79436579
146polyol transport (GO:0015791)2.77769846
147intestinal absorption (GO:0050892)11.6362637
148intestinal cholesterol absorption (GO:0030299)10.3614309

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.80396619
2CDX2_20551321_ChIP-Seq_CACO-2_Human5.68057058
3SOX2_27498859_Chip-Seq_STOMACH_Mouse4.19875401
4HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.36338423
5GATA4_25053715_ChIP-Seq_YYC3_Human3.30874025
6GATA6_25053715_ChIP-Seq_YYC3_Human3.09710505
7PPARA_22158963_ChIP-Seq_LIVER_Mouse2.86580323
8ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.85063086
9* SOX2_20726797_ChIP-Seq_SW620_Human2.80576496
10CDX2_19796622_ChIP-Seq_MESCs_Mouse2.60368293
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.54873310
12LXR_22158963_ChIP-Seq_LIVER_Mouse2.54667752
13RXR_22158963_ChIP-Seq_LIVER_Mouse2.53458606
14SRY_22984422_ChIP-ChIP_TESTIS_Rat2.30153282
15PPAR_26484153_Chip-Seq_NCI-H1993_Human2.08294191
16STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.05068087
17SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.02945282
18TRIM28_21343339_ChIP-Seq_HEK293_Human1.98804890
19CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.94421492
20KLF5_25053715_ChIP-Seq_YYC3_Human1.79371666
21IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.79009264
22FOXO3_23340844_ChIP-Seq_DLD1_Human1.75124437
23ESR1_21235772_ChIP-Seq_MCF-7_Human1.71019796
24FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.70906068
25ESR2_21235772_ChIP-Seq_MCF-7_Human1.69135894
26TCF4_18268006_ChIP-ChIP_LS174T_Human1.69010692
27ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.68628398
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.66786668
29KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.63049400
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.63015375
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.61673679
32ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.61371821
33NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.60262664
34* RUNX1_27514584_Chip-Seq_MCF-7_Human1.59441909
35ZNF263_19887448_ChIP-Seq_K562_Human1.59113020
36RACK7_27058665_Chip-Seq_MCF-7_Human1.54580853
37AR_21909140_ChIP-Seq_LNCAP_Human1.52373565
38PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.51297033
39RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49039443
40* HNF4A_19822575_ChIP-Seq_HepG2_Human1.46928951
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.44561775
42EGR1_23403033_ChIP-Seq_LIVER_Mouse1.43665054
43FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.41720885
44ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.39852896
45BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.39609912
46ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.39108792
47NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.38725454
48* ATF3_27146783_Chip-Seq_COLON_Human1.37286165
49CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.34561635
50RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.31732119
51ESR1_20079471_ChIP-ChIP_T-47D_Human1.30083019
52TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.29988313
53STAT6_21828071_ChIP-Seq_BEAS2B_Human1.29607859
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.27460964
55* FOXA2_19822575_ChIP-Seq_HepG2_Human1.27027516
56SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.26885203
57AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.23877306
58* GATA2_19941826_ChIP-Seq_K562_Human1.23543523
59CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.18303611
60CLOCK_20551151_ChIP-Seq_293T_Human1.17201596
61CREB1_26743006_Chip-Seq_LNCaP_Human1.13351491
62* LXR_22292898_ChIP-Seq_THP-1_Human1.12950742
63VDR_22108803_ChIP-Seq_LS180_Human1.12215182
64CEBPB_22108803_ChIP-Seq_LS180_Human1.11696961
65PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.10278811
66SALL4_18804426_ChIP-ChIP_XEN_Mouse1.09107928
67FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.08601703
68RARG_19884340_ChIP-ChIP_MEFs_Mouse1.08177620
69JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06133404
70HIF1A_21447827_ChIP-Seq_MCF-7_Human1.05672783
71CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03554893
72PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.02997066
73GATA3_24758297_ChIP-Seq_MCF-7_Human1.02885342
74EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02708389
75FOXA1_25552417_ChIP-Seq_VCAP_Human1.02528826
76IRF8_22096565_ChIP-ChIP_GC-B_Human0.99730198
77SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98405125
78CDX2_22108803_ChIP-Seq_LS180_Human0.98306110
79GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97804386
80TCF3_18692474_ChIP-Seq_MEFs_Mouse0.97801222
81FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.97120753
82SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.93225044
83SMAD3_21741376_ChIP-Seq_HESCs_Human0.91411471
84GATA1_22025678_ChIP-Seq_K562_Human0.91208275
85SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.89976359
86SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.89976359
87KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.88254339
88SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.86597435
89PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.85975731
90PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.85257757
91GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.84902174
92EGR1_19032775_ChIP-ChIP_M12_Human0.84478923
93* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.84158082
94KAP1_22055183_ChIP-Seq_ESCs_Mouse0.83682131
95TP63_23658742_ChIP-Seq_EP156T_Human0.82640425
96GATA2_21666600_ChIP-Seq_HMVEC_Human0.82510358
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.82503522
98RXR_22108803_ChIP-Seq_LS180_Human0.80252732
99GATA1_26923725_Chip-Seq_HPCs_Mouse0.79720268
100MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.79530691
101GATA1_19941826_ChIP-Seq_K562_Human0.79245945
102CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.78859560
103TP63_22573176_ChIP-Seq_HFKS_Human0.78841636
104POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.78774674
105EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.77866813
106RAD21_21589869_ChIP-Seq_MESCs_Mouse0.76903854
107BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.76671122
108P300_27058665_Chip-Seq_ZR-75-30cells_Human0.75972313
109P63_26484246_Chip-Seq_KERATINOCYTES_Human0.75684093
110EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.75667853
111SOX9_24532713_ChIP-Seq_HFSC_Mouse0.75405982
112PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.74485944
113NANOG_20526341_ChIP-Seq_ESCs_Human0.74213085
114SOX2_22085726_ChIP-Seq_NPCs_Mouse0.74193665
115GATA1_22383799_ChIP-Seq_G1ME_Mouse0.73930140
116* BCOR_27268052_Chip-Seq_Bcells_Human0.72538431
117JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.72517500
118DROSHA_22980978_ChIP-Seq_HELA_Human0.72120874
119TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.72081435
120TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.71982538
121TET1_21451524_ChIP-Seq_MESCs_Mouse0.71874038
122SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.71132517
123CTCF_27219007_Chip-Seq_Bcells_Human0.70951381
124ESR1_15608294_ChIP-ChIP_MCF-7_Human0.70690979
125ELF5_23300383_ChIP-Seq_T47D_Human0.70462379
126EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.69757860
127SA1_27219007_Chip-Seq_Bcells_Human0.69666800
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.68293756
129SOX2_21211035_ChIP-Seq_LN229_Human0.67113511
130GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.67022021

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.41297170
2MP0001666_abnormal_nutrient_absorption5.45233289
3MP0010234_abnormal_vibrissa_follicle4.50249171
4MP0004264_abnormal_extraembryonic_tissu4.15927206
5MP0000462_abnormal_digestive_system3.53001552
6MP0002139_abnormal_hepatobiliary_system3.34271754
7MP0003183_abnormal_peptide_metabolism3.16714966
8MP0005085_abnormal_gallbladder_physiolo3.15264382
9MP0003866_abnormal_defecation3.02060422
10MP0003252_abnormal_bile_duct2.93771657
11MP0009840_abnormal_foam_cell2.93619856
12MP0008875_abnormal_xenobiotic_pharmacok2.90658554
13MP0004043_abnormal_pH_regulation2.85857580
14MP0002822_catalepsy2.79643468
15MP0005409_darkened_coat_color2.58863062
16MP0005377_hearing/vestibular/ear_phenot2.58042451
17MP0003878_abnormal_ear_physiology2.58042451
18MP0004019_abnormal_vitamin_homeostasis2.34316232
19MP0003283_abnormal_digestive_organ2.30626380
20MP0005365_abnormal_bile_salt2.13987130
21MP0010329_abnormal_lipoprotein_level2.06671336
22MP0005381_digestive/alimentary_phenotyp2.05230816
23MP0000538_abnormal_urinary_bladder2.04878851
24MP0003300_gastrointestinal_ulcer1.98895297
25MP0001663_abnormal_digestive_system1.98003368
26MP0000537_abnormal_urethra_morphology1.96228109
27MP0001873_stomach_inflammation1.89620122
28MP0001664_abnormal_digestion1.87006361
29MP0010155_abnormal_intestine_physiology1.83752267
30MP0010352_gastrointestinal_tract_polyps1.80378577
31MP0004147_increased_porphyrin_level1.78144146
32MP0000566_synostosis1.77040643
33MP0005084_abnormal_gallbladder_morpholo1.76901025
34MP0000477_abnormal_intestine_morphology1.68348214
35MP0009643_abnormal_urine_homeostasis1.67672940
36MP0000490_abnormal_crypts_of1.61996974
37MP0003195_calcinosis1.59871855
38MP0001765_abnormal_ion_homeostasis1.53965125
39MP0003122_maternal_imprinting1.52907734
40MP0006054_spinal_hemorrhage1.44347806
41MP0005670_abnormal_white_adipose1.42333715
42MP0003191_abnormal_cellular_cholesterol1.36157754
43MP0005332_abnormal_amino_acid1.34573183
44MP0005167_abnormal_blood-brain_barrier1.34487288
45MP0003705_abnormal_hypodermis_morpholog1.32391209
46MP0002796_impaired_skin_barrier1.29209852
47MP0003315_abnormal_perineum_morphology1.21178135
48MP0003123_paternal_imprinting1.20748403
49MP0005636_abnormal_mineral_homeostasis1.18909948
50MP0005058_abnormal_lysosome_morphology1.18067814
51MP0005448_abnormal_energy_balance1.15285491
52MP0009780_abnormal_chondrocyte_physiolo1.10168983
53MP0003806_abnormal_nucleotide_metabolis1.08873238
54MP0001849_ear_inflammation1.05384842
55MP0002089_abnormal_postnatal_growth/wei1.05152176
56MP0000678_abnormal_parathyroid_gland1.04200730
57MP0009379_abnormal_foot_pigmentation1.02341624
58MP0002876_abnormal_thyroid_physiology1.01771745
59MP0001188_hyperpigmentation0.96307864
60MP0002136_abnormal_kidney_physiology0.93395690
61MP0002118_abnormal_lipid_homeostasis0.92349644
62MP0010678_abnormal_skin_adnexa0.89184876
63MP0000609_abnormal_liver_physiology0.87471545
64MP0003868_abnormal_feces_composition0.86299612
65MP0002971_abnormal_brown_adipose0.85248604
66MP0002909_abnormal_adrenal_gland0.83660325
67MP0005464_abnormal_platelet_physiology0.82861091
68MP0001756_abnormal_urination0.81568818
69MP0002098_abnormal_vibrissa_morphology0.80997322
70MP0005310_abnormal_salivary_gland0.80204390
71MP0005501_abnormal_skin_physiology0.79673471
72MP0005451_abnormal_body_composition0.78502300
73MP0004947_skin_inflammation0.77780759
74MP0000467_abnormal_esophagus_morphology0.76296658
75MP0009115_abnormal_fat_cell0.74419481
76MP0002254_reproductive_system_inflammat0.74374585
77MP0003638_abnormal_response/metabolism_0.72239362
78MP0005367_renal/urinary_system_phenotyp0.70554346
79MP0000516_abnormal_urinary_system0.70554346
80MP0003718_maternal_effect0.70125516
81MP0000470_abnormal_stomach_morphology0.69275041
82MP0004782_abnormal_surfactant_physiolog0.69051121
83MP0003879_abnormal_hair_cell0.68995168
84MP0009384_cardiac_valve_regurgitation0.68843884
85MP0008872_abnormal_physiological_respon0.68337071
86MP0010386_abnormal_urinary_bladder0.67576473
87MP0005166_decreased_susceptibility_to0.65901528
88MP0002138_abnormal_hepatobiliary_system0.65861512
89MP0002132_abnormal_respiratory_system0.65850907
90MP0003453_abnormal_keratinocyte_physiol0.65641867
91MP0008004_abnormal_stomach_pH0.64902990
92MP0004270_analgesia0.64180720
93MP0005319_abnormal_enzyme/_coenzyme0.63547840
94MP0003172_abnormal_lysosome_physiology0.62653390
95MP0000598_abnormal_liver_morphology0.61879089
96MP0001764_abnormal_homeostasis0.61259177
97MP0008469_abnormal_protein_level0.60620793
98MP0001216_abnormal_epidermal_layer0.59742441
99MP0003693_abnormal_embryo_hatching0.58952015
100MP0000613_abnormal_salivary_gland0.57371432
101MP0009053_abnormal_anal_canal0.55249358
102MP0009642_abnormal_blood_homeostasis0.55093638
103MP0001845_abnormal_inflammatory_respons0.53966114
104MP0009697_abnormal_copulation0.53658587
105MP0004858_abnormal_nervous_system0.53132256
106MP0005266_abnormal_metabolism0.52431288
107MP0008961_abnormal_basal_metabolism0.51467139
108MP0005535_abnormal_body_temperature0.50767627
109MP0000249_abnormal_blood_vessel0.50213878
110MP0002166_altered_tumor_susceptibility0.48892191
111MP0000230_abnormal_systemic_arterial0.48346345
112MP0002078_abnormal_glucose_homeostasis0.48253446
113MP0005584_abnormal_enzyme/coenzyme_acti0.46098819
114MP0003119_abnormal_digestive_system0.45893652
115MP0002277_abnormal_respiratory_mucosa0.45677277
116MP0002693_abnormal_pancreas_physiology0.44096334
117MP0003953_abnormal_hormone_level0.42683413
118MP0001485_abnormal_pinna_reflex0.42508934
119MP0000604_amyloidosis0.42208557
120MP0003941_abnormal_skin_development0.41511331
121MP0001501_abnormal_sleep_pattern0.41290934
122MP0002896_abnormal_bone_mineralization0.40987678
123MP0002396_abnormal_hematopoietic_system0.39288954
124MP0005408_hypopigmentation0.38714567
125MP0005334_abnormal_fat_pad0.37536352
126MP0001191_abnormal_skin_condition0.36277270
127MP0002135_abnormal_kidney_morphology0.36138754
128MP0005666_abnormal_adipose_tissue0.35865116
129MP0005395_other_phenotype0.35526041
130MP0000465_gastrointestinal_hemorrhage0.34313788

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)8.04321720
2Abnormality of glutamine family amino acid metabolism (HP:0010902)6.27591212
3Malnutrition (HP:0004395)5.37975587
4Acanthocytosis (HP:0001927)5.32540930
5Right ventricular cardiomyopathy (HP:0011663)4.96308463
6Conjugated hyperbilirubinemia (HP:0002908)4.82520587
7Hypobetalipoproteinemia (HP:0003563)4.69586609
8Abnormality of proline metabolism (HP:0010907)4.62659539
9Hydroxyprolinuria (HP:0003080)4.62659539
10Deep venous thrombosis (HP:0002625)4.53967334
11Hyperactive renin-angiotensin system (HP:0000841)4.35079941
12Systemic lupus erythematosus (HP:0002725)4.24305283
13Cupped ribs (HP:0000887)4.24067544
14Autoimmune thrombocytopenia (HP:0001973)4.15965840
15Abnormality of chloride homeostasis (HP:0011422)3.92389281
16Abdominal distention (HP:0003270)3.92333914
17Hemorrhage of the eye (HP:0011885)3.80610587
18Widely patent fontanelles and sutures (HP:0004492)3.72901394
19Fat malabsorption (HP:0002630)3.71298962
20Metabolic alkalosis (HP:0200114)3.71066026
21Chronic diarrhea (HP:0002028)3.69213945
22Complement deficiency (HP:0004431)3.60950910
23Glycosuria (HP:0003076)3.46949867
24Abnormality of urine glucose concentration (HP:0011016)3.46949867
25Prolonged partial thromboplastin time (HP:0003645)3.46805495
26Glomerulonephritis (HP:0000099)3.41735510
27Dehydration (HP:0001944)3.35008183
28Hyperglycinuria (HP:0003108)3.31755471
29Autoimmune hemolytic anemia (HP:0001890)3.24206473
30Flat acetabular roof (HP:0003180)3.16656281
31Abnormality of the vitamin B12 metabolism (HP:0004341)3.14805186
32Abnormality of small intestinal villus morphology (HP:0011472)3.13366629
33Villous atrophy (HP:0011473)3.13366629
34Abnormality of purine metabolism (HP:0004352)3.10199715
35Gastrointestinal dysmotility (HP:0002579)3.03308245
36Potter facies (HP:0002009)3.00795686
37Facial shape deformation (HP:0011334)3.00795686
38Joint hemorrhage (HP:0005261)3.00280526
39Epidermoid cyst (HP:0200040)2.97695703
40Abnormality of complement system (HP:0005339)2.97454219
41Pigmentary retinal degeneration (HP:0001146)2.96973745
42Congenital sensorineural hearing impairment (HP:0008527)2.95503439
43Abnormality of vitamin B metabolism (HP:0004340)2.95461551
44Hyperphosphaturia (HP:0003109)2.88586119
45Abnormality of the 1st metacarpal (HP:0010009)2.85480502
46Abnormal biliary tract morphology (HP:0012440)2.82311715
47Intrahepatic cholestasis (HP:0001406)2.82155664
48Poikilocytosis (HP:0004447)2.81667228
49Abnormal tarsal ossification (HP:0008369)2.80177714
50Nausea (HP:0002018)2.75113255
51Nephrolithiasis (HP:0000787)2.73158916
52Hypolipoproteinemia (HP:0010981)2.71398499
53Abnormality of renin-angiotensin system (HP:0000847)2.71086815
54Abnormality of the common coagulation pathway (HP:0010990)2.70752169
55Symptomatic seizures (HP:0011145)2.69812966
56Megaloblastic anemia (HP:0001889)2.60821786
57Hypercholesterolemia (HP:0003124)2.57962908
58Abnormality of monocarboxylic acid metabolism (HP:0010996)2.57525825
59Menorrhagia (HP:0000132)2.51448566
60Vascular calcification (HP:0004934)2.51159792
61Abnormal urine phosphate concentration (HP:0012599)2.50938753
62Proximal tubulopathy (HP:0000114)2.50716148
63Hypotension (HP:0002615)2.50367652
64Steatorrhea (HP:0002570)2.49964626
65Abnormality of aromatic amino acid family metabolism (HP:0004338)2.48539272
66Abnormality of vitamin metabolism (HP:0100508)2.47963242
67Pustule (HP:0200039)2.46388718
68Late onset (HP:0003584)2.43313759
69Hyperammonemia (HP:0001987)2.43302590
70Hypophosphatemic rickets (HP:0004912)2.38850393
71Mildly elevated creatine phosphokinase (HP:0008180)2.37104806
72Gingival bleeding (HP:0000225)2.35466590
73Thin bony cortex (HP:0002753)2.31361451
74Abnormality of the gastric mucosa (HP:0004295)2.30906950
75Wide cranial sutures (HP:0010537)2.30128996
76Abnormality of carpal bone ossification (HP:0006257)2.28927328
77Abnormality of aspartate family amino acid metabolism (HP:0010899)2.27938657
78Nephritis (HP:0000123)2.27385826
79Confusion (HP:0001289)2.27169438
80Progressive sensorineural hearing impairment (HP:0000408)2.27058063
81Milia (HP:0001056)2.26085559
82Palpitations (HP:0001962)2.25790929
83Xanthomatosis (HP:0000991)2.25277757
84Cerebral palsy (HP:0100021)2.23332326
85Rectal prolapse (HP:0002035)2.22920186
86Syncope (HP:0001279)2.22383708
87Abnormality of nucleobase metabolism (HP:0010932)2.21970043
88Woolly hair (HP:0002224)2.21936341
89Abnormality of glycine metabolism (HP:0010895)2.20382149
90Abnormality of serine family amino acid metabolism (HP:0010894)2.20382149
91Hyperparathyroidism (HP:0000843)2.20035891
92Hypoglycemic coma (HP:0001325)2.20016229
93Spontaneous abortion (HP:0005268)2.18616984
94Abnormal glucose tolerance (HP:0001952)2.16693464
95Alkalosis (HP:0001948)2.16366537
96Glomerulosclerosis (HP:0000096)2.15625051
97Growth hormone excess (HP:0000845)2.14293955
98Rickets (HP:0002748)2.13842706
99Hyperaldosteronism (HP:0000859)2.13476218
100Ventricular fibrillation (HP:0001663)2.13171195
101Ureteral stenosis (HP:0000071)2.12510272
102Purpura (HP:0000979)2.11276374
103Hyperlipoproteinemia (HP:0010980)2.11241814
104Cardiovascular calcification (HP:0011915)2.10111664
105Abnormal foot bone ossification (HP:0010675)2.08665222
106Biliary tract neoplasm (HP:0100574)2.08040445
107Hypophosphatemia (HP:0002148)2.07359037
108Hypokalemia (HP:0002900)2.07086102
109Metabolic acidosis (HP:0001942)2.05577662
110Ureteral obstruction (HP:0006000)2.05250950
111Pili torti (HP:0003777)2.04726941
112Metaphyseal irregularity (HP:0003025)2.04570121
113Micronodular cirrhosis (HP:0001413)2.04000875
114Sensorimotor neuropathy (HP:0007141)2.03861931
115Generalized aminoaciduria (HP:0002909)2.02392355
116Increased circulating renin level (HP:0000848)2.02344106
117Abnormal hand bone ossification (HP:0010660)2.02016246
118Ketoacidosis (HP:0001993)2.01441991
119Abnormality of sulfur amino acid metabolism (HP:0004339)2.01334796
120Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.01166058
121Abnormality of magnesium homeostasis (HP:0004921)2.01139710
122Delayed epiphyseal ossification (HP:0002663)1.99422479
123Increased purine levels (HP:0004368)1.99354164
124Hyperuricemia (HP:0002149)1.99354164
125Abnormality of the distal phalanx of the thumb (HP:0009617)1.98650134
126Gout (HP:0001997)1.96692877
127Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.96622611
128Focal segmental glomerulosclerosis (HP:0000097)1.96283290
129Polycythemia (HP:0001901)1.96040937
130Mesangial abnormality (HP:0001966)1.95278130
131Abnormality of renal excretion (HP:0011036)1.95152338
132Enlarged epiphyses (HP:0010580)1.94402013
133Decreased circulating renin level (HP:0003351)1.94062472
134Increased IgE level (HP:0003212)1.93304975
135Skin nodule (HP:0200036)1.92458271
136Abnormality of pyrimidine metabolism (HP:0004353)1.90225474

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B6.21921202
2FRK6.21111740
3MST45.13581666
4LMTK24.99437475
5MST1R4.93812185
6PRKG23.19841681
7NME13.06767233
8FGFR32.87909411
9GRK62.74492368
10MAP2K22.56759635
11MAP3K22.44570808
12EPHA22.42326415
13RIPK12.42030438
14AKT32.14308903
15PTK61.98688522
16MET1.89541223
17WNK41.85224122
18TAOK31.83257439
19PIK3CA1.78476167
20MAP3K101.75574404
21EPHB21.72910747
22NUAK11.65767511
23STK241.60125028
24TAOK11.52511588
25ERN11.49564367
26TNIK1.46071238
27TESK11.45170100
28LATS11.33064272
29KSR21.25795808
30TTK1.24369867
31PRKCI1.21679815
32PTK21.16752964
33TBK11.13631954
34CASK1.11457828
35OXSR11.10927817
36STK101.04810399
37MYLK0.99768363
38ICK0.98173210
39INSRR0.94512565
40STK390.93367185
41MAP3K10.91725355
42MAP3K80.90267874
43FGFR10.88824452
44PRKAA20.86118030
45FER0.83756081
46ERBB20.83725546
47MAP2K60.82221034
48MAP2K10.81555968
49TYK20.81264646
50MAP3K110.80576589
51TYRO30.80564738
52EPHA40.78993286
53NLK0.78773600
54YES10.76973017
55RET0.76922216
56EPHB10.75963361
57SCYL20.73577910
58FGFR20.71801025
59PDPK10.71465494
60PAK40.70558241
61DMPK0.70131698
62DDR20.68569595
63TESK20.68367254
64EPHA30.68276032
65ERBB40.67135485
66BRSK20.65260045
67PBK0.64894640
68STK38L0.62487328
69PRKAA10.62198265
70PRKD30.62092162
71MAPK110.61320531
72MATK0.60857191
73MAP3K70.58517104
74WNK30.57088459
75MAP3K30.56249767
76SIK10.55410607
77MAPKAPK30.52804324
78PRKCZ0.52768108
79BMX0.51286314
80CSF1R0.49734036
81EIF2AK10.46134064
82TRIB30.46028348
83PDK20.45454722
84PAK30.45066656
85CAMK2D0.44496810
86RIPK40.44074569
87FGR0.43015113
88AURKB0.42835505
89PDK10.42235151
90PKN20.41501566
91WNK10.41302392
92MELK0.41026629
93IKBKE0.40450694
94* SRC0.38941466
95MAP3K90.37331525
96IRAK30.36888725
97ITK0.35441651
98PRKCA0.35333610
99STK30.35074315
100DYRK1B0.34164950
101BRAF0.32155157
102IRAK10.31529167
103SGK2230.31272191
104SGK4940.31272191
105LRRK20.31006314
106MAPK150.30746314
107SGK10.28324606
108PDGFRA0.28307595
109MAP3K120.28269645
110CDK90.28099515
111CSNK1E0.27995257
112CSNK1A10.27252578
113IGF1R0.27238937
114GRK10.26710289
115STK110.25175527
116ARAF0.24988197
117GSK3A0.23955250
118FYN0.23879217
119PRKG10.21683338
120LIMK10.21578478
121PRKCQ0.21482012
122PRKACG0.21432070
123CSK0.21108960
124PASK0.21005738
125CDC42BPA0.20817752
126PDK30.20577027
127PDK40.20577027
128RPS6KB10.20358482
129ROCK10.19951377
130DAPK20.19801028
131CAMK2G0.19709229
132NEK10.19204174
133SMG10.19132870
134PRKCB0.17481660
135PAK10.17229323
136EEF2K0.17212285
137CAMK2B0.15314363
138MAPKAPK20.15114775
139CDK120.13331620
140FGFR40.12997705

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049755.17452641
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.60620829
3Mineral absorption_Homo sapiens_hsa049784.17264118
4Renin-angiotensin system_Homo sapiens_hsa046143.94093175
5Sulfur metabolism_Homo sapiens_hsa009203.73462663
6Vitamin digestion and absorption_Homo sapiens_hsa049773.55197735
7Maturity onset diabetes of the young_Homo sapiens_hsa049503.14478818
8Galactose metabolism_Homo sapiens_hsa000522.77079170
9Carbohydrate digestion and absorption_Homo sapiens_hsa049732.65579832
10Starch and sucrose metabolism_Homo sapiens_hsa005002.40673754
11Caffeine metabolism_Homo sapiens_hsa002322.31010716
12Bile secretion_Homo sapiens_hsa049762.27343355
13Protein digestion and absorption_Homo sapiens_hsa049742.25475827
14Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.07973623
15Folate biosynthesis_Homo sapiens_hsa007902.05151958
16Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.02455936
17Fructose and mannose metabolism_Homo sapiens_hsa000512.01796453
18Histidine metabolism_Homo sapiens_hsa003401.88800193
19Complement and coagulation cascades_Homo sapiens_hsa046101.78736965
20Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.73002570
21Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.65182728
22Tryptophan metabolism_Homo sapiens_hsa003801.49093455
23Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.48629701
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.41961778
25Cyanoamino acid metabolism_Homo sapiens_hsa004601.40826666
26Pentose and glucuronate interconversions_Homo sapiens_hsa000401.34788425
27Glutathione metabolism_Homo sapiens_hsa004801.32359643
28Glycerolipid metabolism_Homo sapiens_hsa005611.27295166
29Sphingolipid metabolism_Homo sapiens_hsa006001.22863590
30PPAR signaling pathway_Homo sapiens_hsa033201.20230020
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.19848610
32Fatty acid degradation_Homo sapiens_hsa000711.11970114
33Fatty acid biosynthesis_Homo sapiens_hsa000611.02552183
34Arginine and proline metabolism_Homo sapiens_hsa003300.98830667
35Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.97069915
36Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.95057160
37Butanoate metabolism_Homo sapiens_hsa006500.88579957
38ABC transporters_Homo sapiens_hsa020100.87864489
39Thyroid hormone synthesis_Homo sapiens_hsa049180.85151049
40Arginine biosynthesis_Homo sapiens_hsa002200.84275631
41alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.84116958
42Staphylococcus aureus infection_Homo sapiens_hsa051500.83276711
43Pyruvate metabolism_Homo sapiens_hsa006200.81963293
44Primary bile acid biosynthesis_Homo sapiens_hsa001200.81333721
45Nitrogen metabolism_Homo sapiens_hsa009100.79021789
46Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78216567
472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77752444
48Pancreatic secretion_Homo sapiens_hsa049720.76547774
49Tight junction_Homo sapiens_hsa045300.75698291
50Tyrosine metabolism_Homo sapiens_hsa003500.74730398
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70108403
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68963900
53Pentose phosphate pathway_Homo sapiens_hsa000300.68310223
54Carbon metabolism_Homo sapiens_hsa012000.67759110
55Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.64508766
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.63780072
57Glycerophospholipid metabolism_Homo sapiens_hsa005640.63477651
58beta-Alanine metabolism_Homo sapiens_hsa004100.62021816
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.59257961
60Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.58399106
61Linoleic acid metabolism_Homo sapiens_hsa005910.58369528
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.56410889
63Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55644890
64Type II diabetes mellitus_Homo sapiens_hsa049300.53506742
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52171656
66Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50812011
67Selenocompound metabolism_Homo sapiens_hsa004500.48440207
68Arachidonic acid metabolism_Homo sapiens_hsa005900.44040244
69Gastric acid secretion_Homo sapiens_hsa049710.42855681
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42445155
71Chemical carcinogenesis_Homo sapiens_hsa052040.41683949
72Insulin secretion_Homo sapiens_hsa049110.40841209
73Steroid biosynthesis_Homo sapiens_hsa001000.40423163
74Fatty acid elongation_Homo sapiens_hsa000620.40228711
75Peroxisome_Homo sapiens_hsa041460.40225319
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37941292
77Bladder cancer_Homo sapiens_hsa052190.37195435
78Hepatitis C_Homo sapiens_hsa051600.36678064
79Vibrio cholerae infection_Homo sapiens_hsa051100.36359733
80Thyroid cancer_Homo sapiens_hsa052160.36315862
81Retinol metabolism_Homo sapiens_hsa008300.35373479
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34087622
83Metabolic pathways_Homo sapiens_hsa011000.33153403
84Glucagon signaling pathway_Homo sapiens_hsa049220.32476564
85Leukocyte transendothelial migration_Homo sapiens_hsa046700.31929561
86Lysine degradation_Homo sapiens_hsa003100.31757076
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.31674973
88Fatty acid metabolism_Homo sapiens_hsa012120.31523509
89Adherens junction_Homo sapiens_hsa045200.31192883
90Steroid hormone biosynthesis_Homo sapiens_hsa001400.31091696
91Other glycan degradation_Homo sapiens_hsa005110.28390896
92Salmonella infection_Homo sapiens_hsa051320.27691107
93Ether lipid metabolism_Homo sapiens_hsa005650.25667485
94Intestinal immune network for IgA production_Homo sapiens_hsa046720.25504148
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.22894670
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.22717317
97Inositol phosphate metabolism_Homo sapiens_hsa005620.20025638
98Salivary secretion_Homo sapiens_hsa049700.19793381
99Propanoate metabolism_Homo sapiens_hsa006400.19534858
100Phosphatidylinositol signaling system_Homo sapiens_hsa040700.18708992
101Biosynthesis of amino acids_Homo sapiens_hsa012300.17179957
102Asthma_Homo sapiens_hsa053100.15954853
103Glycosaminoglycan degradation_Homo sapiens_hsa005310.15704366
104Insulin resistance_Homo sapiens_hsa049310.14608400
105Phenylalanine metabolism_Homo sapiens_hsa003600.13188998
106Choline metabolism in cancer_Homo sapiens_hsa052310.12237574
107N-Glycan biosynthesis_Homo sapiens_hsa005100.11983443
108African trypanosomiasis_Homo sapiens_hsa051430.10277345
109Pertussis_Homo sapiens_hsa051330.10144980
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.09426271
111Sulfur relay system_Homo sapiens_hsa041220.07591869
112GnRH signaling pathway_Homo sapiens_hsa049120.07403104
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.06802057
114Alzheimers disease_Homo sapiens_hsa050100.06659410
115Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.06154370
116AMPK signaling pathway_Homo sapiens_hsa041520.04224773
117Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.02989243
118Vitamin B6 metabolism_Homo sapiens_hsa007500.02239731
119Type I diabetes mellitus_Homo sapiens_hsa049400.01964280
120Renin secretion_Homo sapiens_hsa049240.01580860
121Terpenoid backbone biosynthesis_Homo sapiens_hsa00900-0.0154663

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