

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of male gonad development (GO:2000020) | 6.61680548 |
| 2 | negative regulation of metanephros development (GO:0072217) | 5.85513750 |
| 3 | regulation of male gonad development (GO:2000018) | 5.40644038 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 4.99315200 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 4.96823990 |
| 6 | CENP-A containing nucleosome assembly (GO:0034080) | 4.77586631 |
| 7 | cellular response to gonadotropin stimulus (GO:0071371) | 4.72858200 |
| 8 | mesenchymal to epithelial transition (GO:0060231) | 4.44049667 |
| 9 | notochord development (GO:0030903) | 4.33474128 |
| 10 | establishment of integrated proviral latency (GO:0075713) | 4.23713482 |
| 11 | histone exchange (GO:0043486) | 4.09374826 |
| 12 | short-chain fatty acid metabolic process (GO:0046459) | 4.08968121 |
| 13 | IMP biosynthetic process (GO:0006188) | 4.00030550 |
| 14 | metanephric mesenchyme development (GO:0072075) | 3.98108309 |
| 15 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.91887934 |
| 16 | regulation of helicase activity (GO:0051095) | 3.91173049 |
| 17 | ubiquinone biosynthetic process (GO:0006744) | 3.85707713 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.73146875 |
| 19 | peptidyl-histidine modification (GO:0018202) | 3.68121889 |
| 20 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 3.62780900 |
| 21 | mitotic metaphase plate congression (GO:0007080) | 3.61707939 |
| 22 | cardiac right ventricle morphogenesis (GO:0003215) | 3.60825439 |
| 23 | purine nucleobase biosynthetic process (GO:0009113) | 3.60354237 |
| 24 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.56296580 |
| 25 | DNA replication-independent nucleosome organization (GO:0034724) | 3.56296580 |
| 26 | diaphragm development (GO:0060539) | 3.54306284 |
| 27 | anterior/posterior axis specification, embryo (GO:0008595) | 3.53751595 |
| 28 | protein-chromophore linkage (GO:0018298) | 3.51289671 |
| 29 | muscle cell fate commitment (GO:0042693) | 3.50470686 |
| 30 | ubiquinone metabolic process (GO:0006743) | 3.49813532 |
| 31 | skeletal muscle organ development (GO:0060538) | 3.47114598 |
| 32 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.46938008 |
| 33 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.46790494 |
| 34 | regulation of cell proliferation involved in kidney development (GO:1901722) | 3.44784455 |
| 35 | glomerulus development (GO:0032835) | 3.44386033 |
| 36 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.43871976 |
| 37 | muscle hypertrophy in response to stress (GO:0003299) | 3.43871976 |
| 38 | cardiac muscle adaptation (GO:0014887) | 3.43871976 |
| 39 | proteasome assembly (GO:0043248) | 3.43136189 |
| 40 | male genitalia development (GO:0030539) | 3.39288552 |
| 41 | base-excision repair, AP site formation (GO:0006285) | 3.39125706 |
| 42 | DNA damage response, detection of DNA damage (GO:0042769) | 3.32364781 |
| 43 | regulation of cardioblast differentiation (GO:0051890) | 3.31175386 |
| 44 | kidney mesenchyme development (GO:0072074) | 3.30655133 |
| 45 | regulation of gene silencing by RNA (GO:0060966) | 3.30111270 |
| 46 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.30111270 |
| 47 | regulation of gene silencing by miRNA (GO:0060964) | 3.30111270 |
| 48 | pseudouridine synthesis (GO:0001522) | 3.26530996 |
| 49 | IMP metabolic process (GO:0046040) | 3.24654100 |
| 50 | negative regulation of telomerase activity (GO:0051974) | 3.23431838 |
| 51 | DNA demethylation (GO:0080111) | 3.20473830 |
| 52 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.17530350 |
| 53 | positive regulation of heart growth (GO:0060421) | 3.14646775 |
| 54 | response to gonadotropin (GO:0034698) | 3.13756881 |
| 55 | regulation of female gonad development (GO:2000194) | 3.11318985 |
| 56 | termination of RNA polymerase III transcription (GO:0006386) | 3.10691130 |
| 57 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.10691130 |
| 58 | nucleobase biosynthetic process (GO:0046112) | 3.10392495 |
| 59 | establishment of viral latency (GO:0019043) | 3.08652431 |
| 60 | quinone biosynthetic process (GO:1901663) | 3.08393258 |
| 61 | regulation of mitochondrial translation (GO:0070129) | 3.07765523 |
| 62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.05837592 |
| 63 | regulation of meiosis I (GO:0060631) | 3.05190760 |
| 64 | protein targeting to mitochondrion (GO:0006626) | 3.05034951 |
| 65 | rRNA modification (GO:0000154) | 3.03405559 |
| 66 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.02390223 |
| 67 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.02390223 |
| 68 | epithelial cell differentiation involved in kidney development (GO:0035850) | 3.02091283 |
| 69 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.96540719 |
| 70 | ATP synthesis coupled proton transport (GO:0015986) | 2.96540719 |
| 71 | embryonic foregut morphogenesis (GO:0048617) | 2.94695932 |
| 72 | fatty acid elongation (GO:0030497) | 2.93968259 |
| 73 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.93941744 |
| 74 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.93662041 |
| 75 | regulation of glomerulus development (GO:0090192) | 2.93237589 |
| 76 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 2.92275350 |
| 77 | DNA double-strand break processing (GO:0000729) | 2.92047881 |
| 78 | female gonad development (GO:0008585) | 2.90476786 |
| 79 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.89646105 |
| 80 | negative regulation of sister chromatid segregation (GO:0033046) | 2.89646105 |
| 81 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.89646105 |
| 82 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.89646105 |
| 83 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.89646105 |
| 84 | ribosomal small subunit assembly (GO:0000028) | 2.89346438 |
| 85 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.89049455 |
| 86 | regulation of chromatin binding (GO:0035561) | 2.88714203 |
| 87 | metaphase plate congression (GO:0051310) | 2.88491412 |
| 88 | cullin deneddylation (GO:0010388) | 2.85809730 |
| 89 | reproductive system development (GO:0061458) | 2.85535614 |
| 90 | SMAD protein signal transduction (GO:0060395) | 2.85265381 |
| 91 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.83936806 |
| 92 | cellular protein complex localization (GO:0034629) | 2.83882849 |
| 93 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.83112967 |
| 94 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.83112967 |
| 95 | negative regulation of kidney development (GO:0090185) | 2.82678164 |
| 96 | negative regulation of chromosome segregation (GO:0051985) | 2.82365094 |
| 97 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.81825253 |
| 98 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.80391808 |
| 99 | negative regulation of ligase activity (GO:0051352) | 2.80391808 |
| 100 | DNA replication checkpoint (GO:0000076) | 2.79947038 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.03683947 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.84008682 |
| 3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.83514066 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.76967710 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.28832802 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.25333511 |
| 7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.17107004 |
| 8 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.10894270 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.89500587 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.87867712 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.63863680 |
| 12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.60619531 |
| 13 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.56059906 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.53781935 |
| 15 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.53139363 |
| 16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.44756283 |
| 17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.42228967 |
| 18 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.32666145 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.29484694 |
| 20 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.21007120 |
| 21 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.15183958 |
| 22 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.09389340 |
| 23 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.05791424 |
| 24 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.05791424 |
| 25 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.05791424 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97473222 |
| 27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.92604265 |
| 28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.91382882 |
| 29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.87403733 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.87352793 |
| 31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.86883972 |
| 32 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.83964392 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.83465268 |
| 34 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.80408761 |
| 35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.77938614 |
| 36 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.76873066 |
| 37 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.72828497 |
| 38 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.71691104 |
| 39 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.69683973 |
| 40 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.67508096 |
| 41 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.67254129 |
| 42 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.66951490 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.66422683 |
| 44 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.64567614 |
| 45 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.62726253 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.60864467 |
| 47 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.57947150 |
| 48 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.53733128 |
| 49 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.52902375 |
| 50 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.51655995 |
| 51 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.50696204 |
| 52 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.48587617 |
| 53 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.44425353 |
| 54 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.42439017 |
| 55 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.42396505 |
| 56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.40231475 |
| 57 | VDR_22108803_ChIP-Seq_LS180_Human | 1.39875602 |
| 58 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.39386559 |
| 59 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.38329209 |
| 60 | EWS_26573619_Chip-Seq_HEK293_Human | 1.37844648 |
| 61 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.37675523 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.35973814 |
| 63 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34278819 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.31226189 |
| 65 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.29501560 |
| 66 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.29448713 |
| 67 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.29061630 |
| 68 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.29039564 |
| 69 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.27284266 |
| 70 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.27113740 |
| 71 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.26902347 |
| 72 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.21728223 |
| 73 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.20331671 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.20289372 |
| 75 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.16587909 |
| 76 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.16300508 |
| 77 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.16229981 |
| 78 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.13347670 |
| 79 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.07333752 |
| 80 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.06536350 |
| 81 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.04160785 |
| 82 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03642233 |
| 83 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.00645906 |
| 84 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.99964786 |
| 85 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.97450727 |
| 86 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.95232360 |
| 87 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.93927749 |
| 88 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.92782889 |
| 89 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.92593918 |
| 90 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.92332720 |
| 91 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.91148625 |
| 92 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.87250204 |
| 93 | FUS_26573619_Chip-Seq_HEK293_Human | 0.85741972 |
| 94 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84727052 |
| 95 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.84016064 |
| 96 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.82859353 |
| 97 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.81842648 |
| 98 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.81298932 |
| 99 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.71935721 |
| 100 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.71802334 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008995_early_reproductive_senescence | 5.18085800 |
| 2 | MP0008877_abnormal_DNA_methylation | 4.57067393 |
| 3 | MP0003941_abnormal_skin_development | 3.54950022 |
| 4 | MP0000537_abnormal_urethra_morphology | 3.38321595 |
| 5 | MP0003123_paternal_imprinting | 3.34698541 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 3.16597738 |
| 7 | MP0003786_premature_aging | 2.95524083 |
| 8 | MP0003315_abnormal_perineum_morphology | 2.79703921 |
| 9 | MP0003195_calcinosis | 2.78850977 |
| 10 | MP0002254_reproductive_system_inflammat | 2.72846138 |
| 11 | MP0001188_hyperpigmentation | 2.69750798 |
| 12 | MP0003567_abnormal_fetal_cardiomyocyte | 2.58780191 |
| 13 | MP0003693_abnormal_embryo_hatching | 2.56245622 |
| 14 | MP0008058_abnormal_DNA_repair | 2.53425580 |
| 15 | MP0003828_pulmonary_edema | 2.40523259 |
| 16 | MP0003111_abnormal_nucleus_morphology | 2.37872594 |
| 17 | MP0009384_cardiac_valve_regurgitation | 2.19996753 |
| 18 | MP0010094_abnormal_chromosome_stability | 2.15593770 |
| 19 | MP0003718_maternal_effect | 1.95351801 |
| 20 | MP0005367_renal/urinary_system_phenotyp | 1.95280634 |
| 21 | MP0000516_abnormal_urinary_system | 1.95280634 |
| 22 | MP0001919_abnormal_reproductive_system | 1.89360261 |
| 23 | MP0008057_abnormal_DNA_replication | 1.88374907 |
| 24 | MP0003121_genomic_imprinting | 1.85086804 |
| 25 | MP0005423_abnormal_somatic_nervous | 1.75159023 |
| 26 | MP0003119_abnormal_digestive_system | 1.73437240 |
| 27 | MP0008932_abnormal_embryonic_tissue | 1.71850605 |
| 28 | MP0009672_abnormal_birth_weight | 1.66279544 |
| 29 | MP0006036_abnormal_mitochondrial_physio | 1.58016919 |
| 30 | MP0003077_abnormal_cell_cycle | 1.52684501 |
| 31 | MP0000639_abnormal_adrenal_gland | 1.52227974 |
| 32 | MP0008007_abnormal_cellular_replicative | 1.48766413 |
| 33 | MP0001293_anophthalmia | 1.48458365 |
| 34 | MP0001764_abnormal_homeostasis | 1.47590661 |
| 35 | MP0005389_reproductive_system_phenotype | 1.45255639 |
| 36 | MP0003186_abnormal_redox_activity | 1.42825603 |
| 37 | MP0001145_abnormal_male_reproductive | 1.41669091 |
| 38 | MP0005410_abnormal_fertilization | 1.40833630 |
| 39 | MP0001661_extended_life_span | 1.35354565 |
| 40 | MP0002210_abnormal_sex_determination | 1.30773294 |
| 41 | MP0001730_embryonic_growth_arrest | 1.28605904 |
| 42 | MP0006035_abnormal_mitochondrial_morpho | 1.26857921 |
| 43 | MP0003890_abnormal_embryonic-extraembry | 1.26559931 |
| 44 | MP0000653_abnormal_sex_gland | 1.23654634 |
| 45 | MP0001929_abnormal_gametogenesis | 1.19293803 |
| 46 | MP0003011_delayed_dark_adaptation | 1.18801970 |
| 47 | MP0002084_abnormal_developmental_patter | 1.17988413 |
| 48 | MP0004133_heterotaxia | 1.17538008 |
| 49 | MP0003936_abnormal_reproductive_system | 1.14430038 |
| 50 | MP0006292_abnormal_olfactory_placode | 1.12005527 |
| 51 | MP0001119_abnormal_female_reproductive | 1.10357423 |
| 52 | MP0001727_abnormal_embryo_implantation | 1.10086899 |
| 53 | MP0001697_abnormal_embryo_size | 1.07422716 |
| 54 | MP0000467_abnormal_esophagus_morphology | 1.06379594 |
| 55 | MP0009333_abnormal_splenocyte_physiolog | 1.06343149 |
| 56 | MP0003787_abnormal_imprinting | 1.05591216 |
| 57 | MP0000749_muscle_degeneration | 1.03070307 |
| 58 | MP0010030_abnormal_orbit_morphology | 1.02934631 |
| 59 | MP0005220_abnormal_exocrine_pancreas | 1.01647407 |
| 60 | MP0002085_abnormal_embryonic_tissue | 1.01305107 |
| 61 | MP0002295_abnormal_pulmonary_circulatio | 0.98764078 |
| 62 | MP0002089_abnormal_postnatal_growth/wei | 0.95276747 |
| 63 | MP0009703_decreased_birth_body | 0.91098206 |
| 64 | MP0003937_abnormal_limbs/digits/tail_de | 0.90868423 |
| 65 | MP0003698_abnormal_male_reproductive | 0.90804169 |
| 66 | MP0005647_abnormal_sex_gland | 0.90410152 |
| 67 | MP0003137_abnormal_impulse_conducting | 0.89449868 |
| 68 | MP0004019_abnormal_vitamin_homeostasis | 0.87956849 |
| 69 | MP0000350_abnormal_cell_proliferation | 0.87939592 |
| 70 | MP0003942_abnormal_urinary_system | 0.87204630 |
| 71 | MP0003115_abnormal_respiratory_system | 0.85941455 |
| 72 | MP0002697_abnormal_eye_size | 0.85743575 |
| 73 | MP0009379_abnormal_foot_pigmentation | 0.85146925 |
| 74 | MP0002736_abnormal_nociception_after | 0.83805052 |
| 75 | MP0005380_embryogenesis_phenotype | 0.83790080 |
| 76 | MP0001672_abnormal_embryogenesis/_devel | 0.83790080 |
| 77 | MP0003943_abnormal_hepatobiliary_system | 0.80087651 |
| 78 | MP0002102_abnormal_ear_morphology | 0.79794361 |
| 79 | MP0008260_abnormal_autophagy | 0.78333556 |
| 80 | MP0000313_abnormal_cell_death | 0.77715640 |
| 81 | MP0002638_abnormal_pupillary_reflex | 0.76833334 |
| 82 | MP0000049_abnormal_middle_ear | 0.74522295 |
| 83 | MP0002160_abnormal_reproductive_system | 0.74306547 |
| 84 | MP0001984_abnormal_olfaction | 0.72909320 |
| 85 | MP0002938_white_spotting | 0.72617564 |
| 86 | MP0002111_abnormal_tail_morphology | 0.69977868 |
| 87 | MP0002080_prenatal_lethality | 0.68626996 |
| 88 | MP0005395_other_phenotype | 0.68267299 |
| 89 | MP0002086_abnormal_extraembryonic_tissu | 0.64057390 |
| 90 | MP0002229_neurodegeneration | 0.63965297 |
| 91 | MP0003699_abnormal_female_reproductive | 0.63832681 |
| 92 | MP0002161_abnormal_fertility/fecundity | 0.63763743 |
| 93 | MP0000631_abnormal_neuroendocrine_gland | 0.63616624 |
| 94 | MP0003984_embryonic_growth_retardation | 0.62259744 |
| 95 | MP0002088_abnormal_embryonic_growth/wei | 0.62122276 |
| 96 | MP0001177_atelectasis | 0.61985315 |
| 97 | MP0004197_abnormal_fetal_growth/weight/ | 0.61059351 |
| 98 | MP0001286_abnormal_eye_development | 0.60169686 |
| 99 | MP0001485_abnormal_pinna_reflex | 0.57764076 |
| 100 | MP0008872_abnormal_physiological_respon | 0.57589239 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Diaphragmatic weakness (HP:0009113) | 6.53325832 |
| 2 | Gonadal dysgenesis (HP:0000133) | 6.11429426 |
| 3 | Dry hair (HP:0011359) | 5.64295586 |
| 4 | Stridor (HP:0010307) | 5.13768852 |
| 5 | Hyperglycinemia (HP:0002154) | 4.81764450 |
| 6 | Degeneration of anterior horn cells (HP:0002398) | 4.33773454 |
| 7 | Abnormality of the anterior horn cell (HP:0006802) | 4.33773454 |
| 8 | Hypoplastic left heart (HP:0004383) | 4.09106027 |
| 9 | Testicular neoplasm (HP:0010788) | 3.92061134 |
| 10 | Anomalous pulmonary venous return (HP:0010772) | 3.90660513 |
| 11 | Facial diplegia (HP:0001349) | 3.89096478 |
| 12 | Mesangial abnormality (HP:0001966) | 3.77740064 |
| 13 | Abnormal lung lobation (HP:0002101) | 3.76315401 |
| 14 | Male pseudohermaphroditism (HP:0000037) | 3.74568664 |
| 15 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.69383059 |
| 16 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.69383059 |
| 17 | Transposition of the great arteries (HP:0001669) | 3.59253597 |
| 18 | Abnormal connection of the cardiac segments (HP:0011545) | 3.59253597 |
| 19 | Abnormal ventriculo-arterial connection (HP:0011563) | 3.59253597 |
| 20 | Abnormality of the pulmonary veins (HP:0011718) | 3.51880428 |
| 21 | True hermaphroditism (HP:0010459) | 3.49341535 |
| 22 | Tongue fasciculations (HP:0001308) | 3.46020772 |
| 23 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.45215282 |
| 24 | Abnormality of the vocal cords (HP:0008777) | 3.37348528 |
| 25 | Hand muscle atrophy (HP:0009130) | 3.36620873 |
| 26 | Embryonal renal neoplasm (HP:0011794) | 3.26394565 |
| 27 | Hyperglycinuria (HP:0003108) | 3.26292770 |
| 28 | Hypoplastic heart (HP:0001961) | 3.19177083 |
| 29 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.05261379 |
| 30 | Abnormality of glycine metabolism (HP:0010895) | 3.05261379 |
| 31 | Abnormality of the labia minora (HP:0012880) | 3.05144150 |
| 32 | Clumsiness (HP:0002312) | 2.96376188 |
| 33 | Muscle fibrillation (HP:0010546) | 2.95528918 |
| 34 | Spinal muscular atrophy (HP:0007269) | 2.95458857 |
| 35 | Acute encephalopathy (HP:0006846) | 2.91756335 |
| 36 | Gonadotropin excess (HP:0000837) | 2.88641480 |
| 37 | Abnormality of the corticospinal tract (HP:0002492) | 2.84667320 |
| 38 | Hypoplastic pelvis (HP:0008839) | 2.78793040 |
| 39 | Male infertility (HP:0003251) | 2.73174278 |
| 40 | Testicular atrophy (HP:0000029) | 2.67350430 |
| 41 | Osteomalacia (HP:0002749) | 2.62694252 |
| 42 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.61108902 |
| 43 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.60779624 |
| 44 | Female pseudohermaphroditism (HP:0010458) | 2.59726514 |
| 45 | Abnormality of serum amino acid levels (HP:0003112) | 2.58004048 |
| 46 | Methylmalonic acidemia (HP:0002912) | 2.39294292 |
| 47 | Distal upper limb amyotrophy (HP:0007149) | 2.36094886 |
| 48 | Upper limb amyotrophy (HP:0009129) | 2.36094886 |
| 49 | Gout (HP:0001997) | 2.35129189 |
| 50 | Ovarian neoplasm (HP:0100615) | 2.29482454 |
| 51 | Tachypnea (HP:0002789) | 2.25398263 |
| 52 | Multiple enchondromatosis (HP:0005701) | 2.24517562 |
| 53 | Woolly hair (HP:0002224) | 2.24410067 |
| 54 | Increased hepatocellular lipid droplets (HP:0006565) | 2.24042639 |
| 55 | External ophthalmoplegia (HP:0000544) | 2.23723867 |
| 56 | Meckel diverticulum (HP:0002245) | 2.13874838 |
| 57 | Acute necrotizing encephalopathy (HP:0006965) | 2.10060983 |
| 58 | Abnormal number of erythroid precursors (HP:0012131) | 2.06184880 |
| 59 | Lipid accumulation in hepatocytes (HP:0006561) | 2.04542429 |
| 60 | Abnormality of the ileum (HP:0001549) | 2.02782942 |
| 61 | Abnormality of the lower motor neuron (HP:0002366) | 2.00521462 |
| 62 | Primary adrenal insufficiency (HP:0008207) | 1.98156734 |
| 63 | Megaloblastic anemia (HP:0001889) | 1.95795877 |
| 64 | Abnormal sex determination (HP:0012244) | 1.93786089 |
| 65 | Sex reversal (HP:0012245) | 1.93786089 |
| 66 | Colon cancer (HP:0003003) | 1.93136674 |
| 67 | Nausea (HP:0002018) | 1.91583407 |
| 68 | Renal Fanconi syndrome (HP:0001994) | 1.91510399 |
| 69 | Weak cry (HP:0001612) | 1.86320713 |
| 70 | Bulbar palsy (HP:0001283) | 1.85782903 |
| 71 | Embryonal neoplasm (HP:0002898) | 1.85755583 |
| 72 | Birth length less than 3rd percentile (HP:0003561) | 1.85170550 |
| 73 | Hypoventilation (HP:0002791) | 1.84225768 |
| 74 | Methylmalonic aciduria (HP:0012120) | 1.81816959 |
| 75 | Carpal bone hypoplasia (HP:0001498) | 1.80258914 |
| 76 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.78988791 |
| 77 | Bilateral microphthalmos (HP:0007633) | 1.78571442 |
| 78 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.78212850 |
| 79 | Cerebral edema (HP:0002181) | 1.76916629 |
| 80 | Beaking of vertebral bodies (HP:0004568) | 1.74755698 |
| 81 | Shoulder girdle muscle weakness (HP:0003547) | 1.74055238 |
| 82 | Increased CSF lactate (HP:0002490) | 1.73275323 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.72337145 |
| 84 | Myopathic facies (HP:0002058) | 1.71862384 |
| 85 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.71136951 |
| 86 | Mitochondrial inheritance (HP:0001427) | 1.68960228 |
| 87 | Ankle clonus (HP:0011448) | 1.68759620 |
| 88 | Primary amenorrhea (HP:0000786) | 1.68654443 |
| 89 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.67936439 |
| 90 | Abnormality of methionine metabolism (HP:0010901) | 1.67359845 |
| 91 | Progressive macrocephaly (HP:0004481) | 1.63761394 |
| 92 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.62557152 |
| 93 | Impaired vibratory sensation (HP:0002495) | 1.62348249 |
| 94 | Bifid tongue (HP:0010297) | 1.61560342 |
| 95 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.61440639 |
| 96 | Ependymoma (HP:0002888) | 1.61353601 |
| 97 | Microvesicular hepatic steatosis (HP:0001414) | 1.60559238 |
| 98 | Neonatal short-limb short stature (HP:0008921) | 1.60060677 |
| 99 | Abnormality of chromosome stability (HP:0003220) | 1.59463826 |
| 100 | Macrocytic anemia (HP:0001972) | 1.58814243 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PBK | 4.22024101 |
| 2 | VRK2 | 3.95087651 |
| 3 | ACVR1B | 3.84834922 |
| 4 | BUB1 | 3.44780717 |
| 5 | CDC7 | 3.33527008 |
| 6 | TTK | 3.10604923 |
| 7 | SRPK1 | 2.56596101 |
| 8 | ZAK | 2.51665744 |
| 9 | MKNK2 | 2.51560466 |
| 10 | MKNK1 | 2.35476446 |
| 11 | MST4 | 2.33341046 |
| 12 | AKT3 | 2.25983856 |
| 13 | TAF1 | 2.20064421 |
| 14 | PLK3 | 2.17035986 |
| 15 | CDK19 | 2.12076765 |
| 16 | TNIK | 2.08930962 |
| 17 | EIF2AK3 | 2.04924145 |
| 18 | PLK4 | 1.92664172 |
| 19 | NME1 | 1.85216960 |
| 20 | NUAK1 | 1.83563225 |
| 21 | PDK2 | 1.76930823 |
| 22 | PLK1 | 1.75512964 |
| 23 | STK16 | 1.75009635 |
| 24 | VRK1 | 1.65453234 |
| 25 | TSSK6 | 1.56290203 |
| 26 | STK4 | 1.47820014 |
| 27 | WNK3 | 1.35152460 |
| 28 | NME2 | 1.29888245 |
| 29 | DYRK2 | 1.29505028 |
| 30 | TRIM28 | 1.24101268 |
| 31 | BRAF | 1.23600757 |
| 32 | DYRK3 | 1.18933790 |
| 33 | EIF2AK1 | 1.17925063 |
| 34 | STK38L | 1.17090199 |
| 35 | TAOK2 | 1.15730145 |
| 36 | WEE1 | 1.09287100 |
| 37 | ATR | 1.07109839 |
| 38 | ALK | 1.05694760 |
| 39 | CDK4 | 0.97754686 |
| 40 | BRSK2 | 0.96421933 |
| 41 | GRK1 | 0.94038766 |
| 42 | CHEK2 | 0.92289856 |
| 43 | ERBB3 | 0.91775794 |
| 44 | BMPR1B | 0.85519350 |
| 45 | AURKA | 0.82569119 |
| 46 | PRPF4B | 0.80519517 |
| 47 | CDK7 | 0.79950960 |
| 48 | ATM | 0.77321519 |
| 49 | CHEK1 | 0.74659299 |
| 50 | OXSR1 | 0.74503701 |
| 51 | AURKB | 0.72516147 |
| 52 | CSNK1G1 | 0.71880838 |
| 53 | INSRR | 0.61794448 |
| 54 | PAK3 | 0.61591594 |
| 55 | CSNK2A1 | 0.60382828 |
| 56 | PRKCG | 0.58796648 |
| 57 | TNK2 | 0.58352147 |
| 58 | EIF2AK2 | 0.57846583 |
| 59 | CSNK1G2 | 0.57044425 |
| 60 | PNCK | 0.56856459 |
| 61 | CSNK2A2 | 0.55601310 |
| 62 | PASK | 0.54445170 |
| 63 | PRKDC | 0.53573125 |
| 64 | BRSK1 | 0.52810963 |
| 65 | PAK4 | 0.49785936 |
| 66 | PHKG2 | 0.46441557 |
| 67 | PHKG1 | 0.46441557 |
| 68 | MYLK | 0.45835400 |
| 69 | LMTK2 | 0.43378432 |
| 70 | CDK9 | 0.42857785 |
| 71 | DAPK1 | 0.42103387 |
| 72 | CSNK1E | 0.41435539 |
| 73 | MAP3K12 | 0.40494711 |
| 74 | FGFR1 | 0.40300207 |
| 75 | PIM1 | 0.38648302 |
| 76 | CDK3 | 0.38489038 |
| 77 | CDK2 | 0.38477576 |
| 78 | ABL2 | 0.38434649 |
| 79 | STK24 | 0.38348941 |
| 80 | CSNK1G3 | 0.37707443 |
| 81 | CDK1 | 0.36937640 |
| 82 | PAK1 | 0.36642418 |
| 83 | RPS6KC1 | 0.36224094 |
| 84 | RPS6KL1 | 0.36224094 |
| 85 | MELK | 0.35598217 |
| 86 | NEK2 | 0.35361694 |
| 87 | RPS6KA6 | 0.34646354 |
| 88 | RPS6KA5 | 0.34285307 |
| 89 | MAP4K2 | 0.34210793 |
| 90 | CLK1 | 0.34086370 |
| 91 | MAPKAPK5 | 0.33761261 |
| 92 | NEK1 | 0.33200275 |
| 93 | RPS6KA1 | 0.32676056 |
| 94 | PAK6 | 0.29298004 |
| 95 | STK3 | 0.29072945 |
| 96 | CSNK1A1 | 0.28380899 |
| 97 | PRKACB | 0.28089825 |
| 98 | RAF1 | 0.27699091 |
| 99 | PRKACA | 0.27561782 |
| 100 | PRKCE | 0.26426027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.22217981 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.04329391 |
| 3 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.02795306 |
| 4 | Fatty acid elongation_Homo sapiens_hsa00062 | 3.01359694 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 2.93785725 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.69454972 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.63752244 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 2.52226159 |
| 9 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.47093724 |
| 10 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.32138539 |
| 11 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.24408711 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.20550627 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.19286535 |
| 14 | Base excision repair_Homo sapiens_hsa03410 | 2.14768848 |
| 15 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.11573995 |
| 16 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.05353058 |
| 17 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.02056056 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 1.99273923 |
| 19 | Parkinsons disease_Homo sapiens_hsa05012 | 1.92887755 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.88938927 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.86482237 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.85619958 |
| 23 | Protein export_Homo sapiens_hsa03060 | 1.78371374 |
| 24 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.77606754 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.72454654 |
| 26 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.72262818 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.69779565 |
| 28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.63310475 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.57504258 |
| 30 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.51512834 |
| 31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.50161868 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.49051865 |
| 33 | Carbon metabolism_Homo sapiens_hsa01200 | 1.44279517 |
| 34 | Cell cycle_Homo sapiens_hsa04110 | 1.43809600 |
| 35 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.37883686 |
| 36 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.37635856 |
| 37 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.33835948 |
| 38 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.32428622 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.30549900 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.27975686 |
| 41 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.27254919 |
| 42 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.22464879 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.17845958 |
| 44 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.17029117 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 1.11364183 |
| 46 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.10334287 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 1.05883392 |
| 48 | Alzheimers disease_Homo sapiens_hsa05010 | 0.98696525 |
| 49 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.94642713 |
| 50 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.93263074 |
| 51 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.79675804 |
| 52 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.78673943 |
| 53 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.77582350 |
| 54 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.77231385 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76513714 |
| 56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.75272498 |
| 57 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.74714942 |
| 58 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.73229465 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.71303766 |
| 60 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.67781678 |
| 61 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66786204 |
| 62 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.64751724 |
| 63 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.64573845 |
| 64 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.60645401 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60602372 |
| 66 | Galactose metabolism_Homo sapiens_hsa00052 | 0.58461432 |
| 67 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.52845792 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52160124 |
| 69 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.49236126 |
| 70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48587515 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47424082 |
| 72 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.46985933 |
| 73 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.44551187 |
| 74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.43169672 |
| 75 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42134731 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41762782 |
| 77 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41173127 |
| 78 | Phototransduction_Homo sapiens_hsa04744 | 0.41005504 |
| 79 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.40788249 |
| 80 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.40676063 |
| 81 | Thyroid cancer_Homo sapiens_hsa05216 | 0.39973061 |
| 82 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.38915005 |
| 83 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.38114547 |
| 84 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36014388 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34107230 |
| 86 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.33434390 |
| 87 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.28398383 |
| 88 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.27358963 |
| 89 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.27226812 |
| 90 | Circadian rhythm_Homo sapiens_hsa04710 | 0.27068342 |
| 91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.26814018 |
| 92 | Melanoma_Homo sapiens_hsa05218 | 0.26399669 |
| 93 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.23914715 |
| 94 | Histidine metabolism_Homo sapiens_hsa00340 | 0.23302576 |
| 95 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.23251866 |
| 96 | Nicotine addiction_Homo sapiens_hsa05033 | 0.22764471 |
| 97 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.19611792 |
| 98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.19502766 |
| 99 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.19259892 |
| 100 | Tight junction_Homo sapiens_hsa04530 | 0.17163513 |

