VN1R83P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)7.74217297
2nucleobase catabolic process (GO:0046113)5.95978895
3regulation of relaxation of muscle (GO:1901077)5.21025832
4regulation of cell communication by electrical coupling (GO:0010649)5.06356659
5neural tube formation (GO:0001841)4.94497836
6negative regulation of sodium ion transport (GO:0010766)4.70532332
7regulation of action potential (GO:0098900)4.67287048
8presynaptic membrane assembly (GO:0097105)4.30956076
9response to pheromone (GO:0019236)4.30880384
10atrial cardiac muscle cell action potential (GO:0086014)3.98827361
11negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.96393024
12negative regulation of translation, ncRNA-mediated (GO:0040033)3.96393024
13regulation of translation, ncRNA-mediated (GO:0045974)3.96393024
14female gonad development (GO:0008585)3.86887230
15sympathetic nervous system development (GO:0048485)3.77744058
16glycosphingolipid biosynthetic process (GO:0006688)3.70853363
17presynaptic membrane organization (GO:0097090)3.69174256
18regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.62995580
19regulation of mitotic spindle checkpoint (GO:1903504)3.62995580
20DNA damage response, detection of DNA damage (GO:0042769)3.61040778
21retinal ganglion cell axon guidance (GO:0031290)3.56307878
22attachment of spindle microtubules to kinetochore (GO:0008608)3.49315418
23regulation of centriole replication (GO:0046599)3.49040627
24pre-miRNA processing (GO:0031054)3.45403183
25olfactory bulb development (GO:0021772)3.42153868
26regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.41652326
27histone H2A acetylation (GO:0043968)3.37105702
28DNA ligation (GO:0006266)3.31832039
29regulation of Rac protein signal transduction (GO:0035020)3.29481438
30relaxation of cardiac muscle (GO:0055119)3.26709679
31limb bud formation (GO:0060174)3.26111495
32regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.25752688
33positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.25752688
34positive regulation of cardiac muscle hypertrophy (GO:0010613)3.22573078
35positive regulation of muscle hypertrophy (GO:0014742)3.22573078
36intraciliary transport (GO:0042073)3.20156623
37central nervous system projection neuron axonogenesis (GO:0021952)3.19022183
38centrosome duplication (GO:0051298)3.13169475
39neuronal action potential propagation (GO:0019227)3.08754756
40regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.08698880
41regulation of feeding behavior (GO:0060259)3.07185710
42regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.06574187
43DNA integration (GO:0015074)3.02639551
44establishment of nucleus localization (GO:0040023)3.02515242
45adenosine metabolic process (GO:0046085)2.97482597
46keratinocyte development (GO:0003334)2.93907261
47negative regulation of synaptic transmission, GABAergic (GO:0032229)2.92808300
48negative regulation of B cell proliferation (GO:0030889)2.90377842
49peptidyl-cysteine modification (GO:0018198)2.84883035
50negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.84311682
51DNA double-strand break processing (GO:0000729)2.83571529
52kinetochore organization (GO:0051383)2.82169416
53acrosome assembly (GO:0001675)2.80620939
54regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.80040769
55regulation of heart rate by cardiac conduction (GO:0086091)2.79843622
56regulation of non-canonical Wnt signaling pathway (GO:2000050)2.78899317
57neuron cell-cell adhesion (GO:0007158)2.77983245
58kinetochore assembly (GO:0051382)2.77323840
59C4-dicarboxylate transport (GO:0015740)2.77175739
60regulation of centrosome duplication (GO:0010824)2.75719872
61postsynaptic membrane organization (GO:0001941)2.74856052
62spindle checkpoint (GO:0031577)2.73232933
63central nervous system neuron axonogenesis (GO:0021955)2.72798658
64natural killer cell activation involved in immune response (GO:0002323)2.67268653
65negative chemotaxis (GO:0050919)2.64721089
66mitotic spindle checkpoint (GO:0071174)2.63692060
67vocalization behavior (GO:0071625)2.60600576
68single strand break repair (GO:0000012)2.57035594
69negative regulation of DNA-dependent DNA replication (GO:2000104)2.56362532
70regulation of centrosome cycle (GO:0046605)2.55730150
71protein localization to cilium (GO:0061512)2.55669352
72regulation of dendritic spine morphogenesis (GO:0061001)2.55227753
73microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.52096866
74embryonic epithelial tube formation (GO:0001838)2.51793822
75ganglion development (GO:0061548)2.50520519
76spermatid nucleus differentiation (GO:0007289)2.50467687
77preassembly of GPI anchor in ER membrane (GO:0016254)2.49990537
78microtubule anchoring (GO:0034453)2.48850883
79positive regulation of mitotic sister chromatid separation (GO:1901970)2.48376916
80positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.48376916
81positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.48376916
82positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.47718589
83branched-chain amino acid catabolic process (GO:0009083)2.46558327
84myelin assembly (GO:0032288)2.45799460
85neuron recognition (GO:0008038)2.45186945
86glial cell proliferation (GO:0014009)2.44563492
87RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.44440178
88recombinational repair (GO:0000725)2.44170805
89ephrin receptor signaling pathway (GO:0048013)2.43992656
90forebrain neuron differentiation (GO:0021879)2.43927390
91spinal cord development (GO:0021510)2.42356410
92cilium morphogenesis (GO:0060271)2.42351029
93positive regulation of oligodendrocyte differentiation (GO:0048714)2.41196409
94epithelial tube formation (GO:0072175)2.38340398
95regulation of axon guidance (GO:1902667)2.38274010
96regulation of oligodendrocyte differentiation (GO:0048713)2.37852365
97double-strand break repair via homologous recombination (GO:0000724)2.37668204
98mitotic metaphase plate congression (GO:0007080)2.37420413
99fatty acid elongation (GO:0030497)2.36593784
100photoreceptor cell maintenance (GO:0045494)2.35936375

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SALL1_21062744_ChIP-ChIP_HESCs_Human4.11260681
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.28565187
3IGF1R_20145208_ChIP-Seq_DFB_Human3.10474239
4CEBPD_23245923_ChIP-Seq_MEFs_Mouse3.09036381
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.98297578
6GBX2_23144817_ChIP-Seq_PC3_Human2.88648089
7ZNF274_21170338_ChIP-Seq_K562_Hela2.81643565
8TAF15_26573619_Chip-Seq_HEK293_Human2.80952065
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.80601657
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.61934710
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.43210993
12FUS_26573619_Chip-Seq_HEK293_Human2.39604386
13AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.38527669
14EWS_26573619_Chip-Seq_HEK293_Human2.36038313
15P300_19829295_ChIP-Seq_ESCs_Human2.21464547
16PIAS1_25552417_ChIP-Seq_VCAP_Human2.19492152
17BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.11902071
18PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.11822986
19SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.11787821
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.02134991
21SMAD_19615063_ChIP-ChIP_OVARY_Human2.01566228
22FOXM1_23109430_ChIP-Seq_U2OS_Human1.91609214
23SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.90267197
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.89956516
25OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.83457533
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.74524307
27MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.74408392
28SMAD4_21799915_ChIP-Seq_A2780_Human1.72744976
29E2F4_17652178_ChIP-ChIP_JURKAT_Human1.64520787
30EZH2_22144423_ChIP-Seq_EOC_Human1.63850201
31EZH2_27294783_Chip-Seq_NPCs_Mouse1.62395732
32TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.62168901
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.59206435
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57167601
35SMAD3_21741376_ChIP-Seq_EPCs_Human1.56605573
36UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.54514978
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.51956776
38ER_23166858_ChIP-Seq_MCF-7_Human1.51276858
39SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.48929641
40NANOG_18555785_Chip-Seq_ESCs_Mouse1.47472835
41STAT3_23295773_ChIP-Seq_U87_Human1.46792943
42TCF4_22108803_ChIP-Seq_LS180_Human1.43927958
43SUZ12_27294783_Chip-Seq_NPCs_Mouse1.41248496
44PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40295805
45CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.40288379
46RUNX2_22187159_ChIP-Seq_PCA_Human1.39399281
47KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.39333507
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.38921366
49VDR_22108803_ChIP-Seq_LS180_Human1.38600144
50AR_25329375_ChIP-Seq_VCAP_Human1.35569981
51TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33270355
52POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33270355
53TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32406977
54CMYC_18555785_Chip-Seq_ESCs_Mouse1.32238424
55MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32084792
56P53_22387025_ChIP-Seq_ESCs_Mouse1.32076037
57EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.30808751
58E2F1_18555785_Chip-Seq_ESCs_Mouse1.30266506
59CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.29756583
60TCF4_23295773_ChIP-Seq_U87_Human1.28439060
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28337503
62SUZ12_18555785_Chip-Seq_ESCs_Mouse1.27021496
63MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25770693
64FOXM1_26456572_ChIP-Seq_MCF-7_Human1.23629422
65P300_18555785_Chip-Seq_ESCs_Mouse1.23226166
66AR_21572438_ChIP-Seq_LNCaP_Human1.23121013
67NFE2_27457419_Chip-Seq_LIVER_Mouse1.23050443
68BCAT_22108803_ChIP-Seq_LS180_Human1.22299356
69WT1_19549856_ChIP-ChIP_CCG9911_Human1.21278125
70PRDM14_20953172_ChIP-Seq_ESCs_Human1.21109763
71CRX_20693478_ChIP-Seq_RETINA_Mouse1.20673866
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.19942743
73KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19565595
74NR3C1_23031785_ChIP-Seq_PC12_Mouse1.19193895
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19114158
76CBP_20019798_ChIP-Seq_JUKART_Human1.19114158
77NR3C1_21868756_ChIP-Seq_MCF10A_Human1.18942917
78CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18718754
79ELK1_19687146_ChIP-ChIP_HELA_Human1.18655814
80TCF4_18268006_ChIP-ChIP_LS174T_Human1.17949824
81TP63_19390658_ChIP-ChIP_HaCaT_Human1.17904960
82CBX2_27304074_Chip-Seq_ESCs_Mouse1.15608405
83PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15394410
84FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.14867498
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13560474
86TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13496566
87TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12755046
88TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.12397742
89OCT4_21477851_ChIP-Seq_ESCs_Mouse1.10883148
90AHR_22903824_ChIP-Seq_MCF-7_Human1.10484057
91SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.10094611
92GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09602872
93POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08541471
94STAT3_18555785_Chip-Seq_ESCs_Mouse1.08399877
95SOX9_26525672_Chip-Seq_HEART_Mouse1.07304733
96JUN_21703547_ChIP-Seq_K562_Human1.06528390
97KDM2B_26808549_Chip-Seq_REH_Human1.06444641
98SOX2_18555785_Chip-Seq_ESCs_Mouse1.06033277
99KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04639425
100HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.04471578

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.84926199
2MP0003787_abnormal_imprinting3.47741574
3MP0002009_preneoplasia3.42538995
4MP0008877_abnormal_DNA_methylation3.37603990
5MP0008057_abnormal_DNA_replication2.94650398
6MP0002254_reproductive_system_inflammat2.84636752
7MP0006292_abnormal_olfactory_placode2.80051148
8MP0003122_maternal_imprinting2.64602311
9MP0003890_abnormal_embryonic-extraembry2.53611277
10MP0003121_genomic_imprinting2.42814355
11MP0001177_atelectasis2.35592589
12MP0006054_spinal_hemorrhage2.34928499
13MP0000372_irregular_coat_pigmentation2.25512282
14MP0008058_abnormal_DNA_repair2.24761880
15MP0002138_abnormal_hepatobiliary_system2.21888162
16MP0000778_abnormal_nervous_system2.10176278
17MP0002751_abnormal_autonomic_nervous2.03241044
18MP0001486_abnormal_startle_reflex1.97635076
19MP0003011_delayed_dark_adaptation1.96299713
20MP0009046_muscle_twitch1.96050787
21MP0005253_abnormal_eye_physiology1.87301655
22MP0010094_abnormal_chromosome_stability1.78832360
23MP0004133_heterotaxia1.72201402
24MP0004147_increased_porphyrin_level1.61426405
25MP0004270_analgesia1.60300482
26MP0000569_abnormal_digit_pigmentation1.56480965
27MP0005075_abnormal_melanosome_morpholog1.55511548
28MP0001485_abnormal_pinna_reflex1.53117246
29MP0005551_abnormal_eye_electrophysiolog1.50698499
30MP0003195_calcinosis1.44682806
31MP0004484_altered_response_of1.40202297
32MP0003868_abnormal_feces_composition1.36313750
33MP0005423_abnormal_somatic_nervous1.35990144
34MP0002938_white_spotting1.34897196
35MP0008789_abnormal_olfactory_epithelium1.32341336
36MP0001984_abnormal_olfaction1.30849790
37MP0003937_abnormal_limbs/digits/tail_de1.29363416
38MP0003567_abnormal_fetal_cardiomyocyte1.26831844
39MP0000013_abnormal_adipose_tissue1.20556911
40MP0000383_abnormal_hair_follicle1.19979869
41MP0002184_abnormal_innervation1.18788048
42MP0001293_anophthalmia1.18298137
43MP0000955_abnormal_spinal_cord1.16741296
44MP0002736_abnormal_nociception_after1.15501508
45MP0003221_abnormal_cardiomyocyte_apopto1.15381210
46MP0002233_abnormal_nose_morphology1.11614620
47MP0003935_abnormal_craniofacial_develop1.11272695
48MP0003861_abnormal_nervous_system1.11093719
49MP0001324_abnormal_eye_pigmentation1.08370999
50MP0005391_vision/eye_phenotype1.07859796
51MP0002928_abnormal_bile_duct1.06479061
52MP0006276_abnormal_autonomic_nervous1.05939772
53MP0002234_abnormal_pharynx_morphology1.04727537
54MP0004811_abnormal_neuron_physiology1.03932568
55MP0003755_abnormal_palate_morphology1.03644224
56MP0002168_other_aberrant_phenotype1.01748311
57MP0002272_abnormal_nervous_system1.00455407
58MP0004883_abnormal_blood_vessel0.99777944
59MP0006072_abnormal_retinal_apoptosis0.99175071
60MP0002282_abnormal_trachea_morphology0.98369008
61MP0002064_seizures0.97716567
62MP0003077_abnormal_cell_cycle0.97102083
63MP0001286_abnormal_eye_development0.96354842
64MP0005248_abnormal_Harderian_gland0.95394047
65MP0003385_abnormal_body_wall0.95084005
66MP0005084_abnormal_gallbladder_morpholo0.94610634
67MP0004742_abnormal_vestibular_system0.94405174
68MP0004264_abnormal_extraembryonic_tissu0.93841703
69MP0004859_abnormal_synaptic_plasticity0.92114822
70MP0002127_abnormal_cardiovascular_syste0.92069571
71MP0002752_abnormal_somatic_nervous0.89886469
72MP0003635_abnormal_synaptic_transmissio0.89410046
73MP0001529_abnormal_vocalization0.89094429
74MP0002102_abnormal_ear_morphology0.88932575
75MP0002152_abnormal_brain_morphology0.88113335
76MP0001968_abnormal_touch/_nociception0.86411326
77MP0008872_abnormal_physiological_respon0.83671879
78MP0009745_abnormal_behavioral_response0.80147924
79MP0000427_abnormal_hair_cycle0.80004567
80MP0000647_abnormal_sebaceous_gland0.78861789
81MP0009703_decreased_birth_body0.78339107
82MP0002882_abnormal_neuron_morphology0.75237107
83MP0004197_abnormal_fetal_growth/weight/0.74412253
84MP0005195_abnormal_posterior_eye0.70953160
85MP0002081_perinatal_lethality0.69895006
86MP0002084_abnormal_developmental_patter0.69845168
87MP0001666_abnormal_nutrient_absorption0.69084313
88MP0002063_abnormal_learning/memory/cond0.68613985
89MP0010678_abnormal_skin_adnexa0.68552674
90MP0003698_abnormal_male_reproductive0.66639055
91MP0002088_abnormal_embryonic_growth/wei0.66499600
92MP0003943_abnormal_hepatobiliary_system0.66259308
93MP0005187_abnormal_penis_morphology0.65461016
94MP0004215_abnormal_myocardial_fiber0.64892465
95MP0009697_abnormal_copulation0.63924305
96MP0003984_embryonic_growth_retardation0.62879182
97MP0000049_abnormal_middle_ear0.62166686
98MP0000613_abnormal_salivary_gland0.61569848
99MP0005380_embryogenesis_phenotype0.60685574
100MP0001672_abnormal_embryogenesis/_devel0.60685574

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.45966402
2Broad alveolar ridges (HP:0000187)4.14004978
3Papillary thyroid carcinoma (HP:0002895)3.93775245
4Focal seizures (HP:0007359)3.30223905
5Tubulointerstitial nephritis (HP:0001970)2.98116475
6Thyroid carcinoma (HP:0002890)2.98092694
7Hepatoblastoma (HP:0002884)2.91471492
8Cortical dysplasia (HP:0002539)2.85915945
9Absent speech (HP:0001344)2.85598999
10Drooling (HP:0002307)2.79119440
11Volvulus (HP:0002580)2.75218651
12Median cleft lip (HP:0000161)2.69843478
13Hypoplastic iliac wings (HP:0002866)2.63178790
14Lissencephaly (HP:0001339)2.62858381
15Neonatal respiratory distress (HP:0002643)2.60344705
16Thyroiditis (HP:0100646)2.59387210
17Excessive salivation (HP:0003781)2.55977522
18Hyperventilation (HP:0002883)2.54417606
19Thickened helices (HP:0000391)2.53984624
20Mesomelia (HP:0003027)2.53862474
21Colon cancer (HP:0003003)2.47150405
22Abnormality of macular pigmentation (HP:0008002)2.46272048
23Long clavicles (HP:0000890)2.42155883
24Neoplasm of the adrenal cortex (HP:0100641)2.41627672
25Postaxial foot polydactyly (HP:0001830)2.35768894
26Pancreatic cysts (HP:0001737)2.33487083
27Atonic seizures (HP:0010819)2.31706988
28Nephronophthisis (HP:0000090)2.30278161
29Aqueductal stenosis (HP:0002410)2.28234161
30Generalized myoclonic seizures (HP:0002123)2.27892116
31Gaze-evoked nystagmus (HP:0000640)2.23642846
32High anterior hairline (HP:0009890)2.22148703
33Stomach cancer (HP:0012126)2.21336589
34B lymphocytopenia (HP:0010976)2.20584841
35Abnormality of the labia minora (HP:0012880)2.20379455
36Abnormality of the renal medulla (HP:0100957)2.20356172
37Optic nerve hypoplasia (HP:0000609)2.20273982
38Severe combined immunodeficiency (HP:0004430)2.20212635
39Dialeptic seizures (HP:0011146)2.18773788
40Glioma (HP:0009733)2.18094248
41Amyotrophic lateral sclerosis (HP:0007354)2.16680148
42Febrile seizures (HP:0002373)2.13461505
43Intestinal atresia (HP:0011100)2.13215691
44Anterior segment dysgenesis (HP:0007700)2.12207416
45Chronic hepatic failure (HP:0100626)2.11308744
46Medial flaring of the eyebrow (HP:0010747)2.09395331
47Tented upper lip vermilion (HP:0010804)2.03419678
48Poor speech (HP:0002465)2.02803373
49Supernumerary spleens (HP:0009799)2.01524618
50Central scotoma (HP:0000603)1.99980980
51Abnormality of the alveolar ridges (HP:0006477)1.98719252
52Abnormality of B cell number (HP:0010975)1.98280561
53Epidermoid cyst (HP:0200040)1.97445686
54Postaxial hand polydactyly (HP:0001162)1.97069418
55Short foot (HP:0001773)1.96519106
56Pancreatic fibrosis (HP:0100732)1.95919656
57Oligodactyly (hands) (HP:0001180)1.93707194
58True hermaphroditism (HP:0010459)1.93387058
59Curly hair (HP:0002212)1.93261294
60Broad palm (HP:0001169)1.92858909
61Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.92030240
62Gait imbalance (HP:0002141)1.91868551
63Abnormality of the astrocytes (HP:0100707)1.90390640
64Astrocytoma (HP:0009592)1.90390640
65Genital tract atresia (HP:0001827)1.87841677
66Aplasia/Hypoplasia of the tibia (HP:0005772)1.87638683
67Congenital primary aphakia (HP:0007707)1.87007981
68Molar tooth sign on MRI (HP:0002419)1.84222802
69Abnormality of midbrain morphology (HP:0002418)1.84222802
70Hypoplastic pelvis (HP:0008839)1.84217498
71Retinal dysplasia (HP:0007973)1.83436651
72Pendular nystagmus (HP:0012043)1.83158819
73Pachygyria (HP:0001302)1.81838571
74Abnormality of the pubic bones (HP:0003172)1.81564010
75Preaxial hand polydactyly (HP:0001177)1.81440335
76Abnormal umbilical cord blood vessels (HP:0011403)1.80892983
77Single umbilical artery (HP:0001195)1.80892983
78Abnormality of the fetal cardiovascular system (HP:0010948)1.80892983
79Aplasia/Hypoplasia of the tongue (HP:0010295)1.76894043
80Diastasis recti (HP:0001540)1.76730558
81Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.76581860
82Cerebellar dysplasia (HP:0007033)1.76009425
83Neoplasm of the tracheobronchial system (HP:0100552)1.74891416
84Nephrogenic diabetes insipidus (HP:0009806)1.73911635
85Combined immunodeficiency (HP:0005387)1.72580258
86Oculomotor apraxia (HP:0000657)1.71609496
87Short chin (HP:0000331)1.70844962
88Renal hypoplasia (HP:0000089)1.70726178
89Widely spaced teeth (HP:0000687)1.70565503
90Wrist flexion contracture (HP:0001239)1.69361354
91Cerebral hypomyelination (HP:0006808)1.68987243
92Generalized tonic-clonic seizures (HP:0002069)1.66427578
93Type II lissencephaly (HP:0007260)1.66158374
94Stage 5 chronic kidney disease (HP:0003774)1.65932698
95Transitional cell carcinoma of the bladder (HP:0006740)1.65682976
96Short tibia (HP:0005736)1.65614426
97Abnormality of the fovea (HP:0000493)1.65097299
98Scanning speech (HP:0002168)1.64973587
99Abnormality of chromosome segregation (HP:0002916)1.64874744
100Hip dysplasia (HP:0001385)1.64582909

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIM284.32975585
2WNK34.32469293
3MAP4K23.80175920
4MARK13.56699322
5MAP3K43.40261514
6SIK33.10943680
7CASK2.49332744
8BCR2.48638589
9PINK12.24599055
10BRD42.20920613
11FRK2.18792997
12MAPK131.84934782
13MAP2K71.78871335
14CDK191.75359555
15SRPK11.71940686
16ZAK1.66378437
17STK391.65465521
18MAP3K61.58592702
19PAK31.53935607
20MINK11.53604166
21CCNB11.52828606
22WEE11.46828422
23TTK1.41101458
24MKNK21.39777379
25EIF2AK31.36841172
26MAP2K41.34777866
27GRK11.24988584
28TAF11.22950003
29PLK31.20644652
30MKNK11.20462390
31AKT31.16220334
32FGR1.15254146
33IRAK21.14995733
34PLK41.14318676
35TSSK61.09369728
36YES11.07870037
37PIK3CA1.07150141
38BMPR21.05564336
39DYRK31.04363950
40ERBB31.01047098
41IRAK10.96973137
42FGFR20.89565618
43SIK20.86741453
44CAMKK20.81587129
45UHMK10.80068326
46BMPR1B0.78778962
47OXSR10.78143871
48PNCK0.77476204
49DYRK20.76129290
50SGK20.75174748
51NLK0.73041633
52ACVR1B0.68571952
53KSR10.68265325
54TGFBR20.67598826
55PLK20.65293402
56CDK30.61609297
57EIF2AK20.61093992
58PKN10.60592888
59NEK60.59111102
60BRSK20.58911264
61CDK90.55338023
62SGK30.55249445
63PRKCE0.54503710
64PLK10.54452135
65DYRK1A0.53917513
66NTRK20.53626554
67EPHA40.53256415
68NEK10.52046911
69ROCK10.51669740
70RPS6KB10.51407963
71MAP2K30.51178011
72SGK4940.50499175
73SGK2230.50499175
74WNK40.49686146
75CDK50.48817001
76TRPM70.47446466
77CSNK1G10.46772949
78CAMK40.45706430
79ATR0.45355204
80CDK60.41208150
81CSNK1D0.40843574
82CSNK1A1L0.40122846
83ATM0.39013727
84MAP3K140.37840007
85TNIK0.35113411
86AURKB0.33720696
87CAMK2D0.32564293
88CLK10.31642028
89CHEK10.31501992
90CDK180.30319537
91MAP3K50.29041711
92STK40.29036271
93MST40.28802606
94STK110.28748432
95ERBB40.28650738
96ERBB20.28638358
97CSNK1G20.27709765
98MAP2K10.26461509
99ABL10.26222943
100MUSK0.26215233

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.45914575
2Non-homologous end-joining_Homo sapiens_hsa034502.80636323
3Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.73250426
4Phototransduction_Homo sapiens_hsa047442.64349606
5Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.29837135
6Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.25151362
7Propanoate metabolism_Homo sapiens_hsa006402.03037573
8beta-Alanine metabolism_Homo sapiens_hsa004102.01616353
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.97705487
10Protein export_Homo sapiens_hsa030601.94838859
11Butanoate metabolism_Homo sapiens_hsa006501.69996962
12Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.69673888
13Nicotine addiction_Homo sapiens_hsa050331.68462147
14Basal transcription factors_Homo sapiens_hsa030221.67368657
15Olfactory transduction_Homo sapiens_hsa047401.56932802
16Homologous recombination_Homo sapiens_hsa034401.56450169
17Fanconi anemia pathway_Homo sapiens_hsa034601.51975958
18Oocyte meiosis_Homo sapiens_hsa041141.51350279
19Axon guidance_Homo sapiens_hsa043601.48066114
20Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.41554005
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38334940
22Ether lipid metabolism_Homo sapiens_hsa005651.35847613
23Lysine degradation_Homo sapiens_hsa003101.34798673
24Taste transduction_Homo sapiens_hsa047421.24345581
25Circadian entrainment_Homo sapiens_hsa047131.23501091
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.19880834
27Wnt signaling pathway_Homo sapiens_hsa043101.17358364
28Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.16728183
29Amphetamine addiction_Homo sapiens_hsa050311.14731581
30Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.07265866
31Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.06872998
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06257284
33Gastric acid secretion_Homo sapiens_hsa049711.04514917
34Long-term potentiation_Homo sapiens_hsa047201.03485958
35Nucleotide excision repair_Homo sapiens_hsa034201.02797699
36Colorectal cancer_Homo sapiens_hsa052101.02108308
37TGF-beta signaling pathway_Homo sapiens_hsa043501.00850508
38Hedgehog signaling pathway_Homo sapiens_hsa043400.99366020
39Melanogenesis_Homo sapiens_hsa049160.97846257
40Dopaminergic synapse_Homo sapiens_hsa047280.97441550
41Hippo signaling pathway_Homo sapiens_hsa043900.95996553
42Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.95919563
43p53 signaling pathway_Homo sapiens_hsa041150.92957231
44Cell cycle_Homo sapiens_hsa041100.92281723
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90772036
46Primary bile acid biosynthesis_Homo sapiens_hsa001200.90741635
47Dorso-ventral axis formation_Homo sapiens_hsa043200.87928014
48Steroid biosynthesis_Homo sapiens_hsa001000.86195468
49Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.84411037
50RNA degradation_Homo sapiens_hsa030180.84400562
51Nitrogen metabolism_Homo sapiens_hsa009100.83423320
52RNA transport_Homo sapiens_hsa030130.81646216
53Adherens junction_Homo sapiens_hsa045200.81138394
54Fatty acid metabolism_Homo sapiens_hsa012120.80777169
55Primary immunodeficiency_Homo sapiens_hsa053400.79346990
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77528933
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.77436381
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.77293294
59FoxO signaling pathway_Homo sapiens_hsa040680.76432823
60Linoleic acid metabolism_Homo sapiens_hsa005910.75779106
61Shigellosis_Homo sapiens_hsa051310.75370729
62Glioma_Homo sapiens_hsa052140.72472015
63Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.70758368
64cAMP signaling pathway_Homo sapiens_hsa040240.70526095
65GABAergic synapse_Homo sapiens_hsa047270.68509850
66Cholinergic synapse_Homo sapiens_hsa047250.67412538
67Fatty acid elongation_Homo sapiens_hsa000620.67187887
68Glutamatergic synapse_Homo sapiens_hsa047240.66329421
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65393537
70Tight junction_Homo sapiens_hsa045300.64996621
71Salivary secretion_Homo sapiens_hsa049700.64967048
72Spliceosome_Homo sapiens_hsa030400.64614359
73Glucagon signaling pathway_Homo sapiens_hsa049220.64607967
74Base excision repair_Homo sapiens_hsa034100.64163724
75Gap junction_Homo sapiens_hsa045400.63808317
76Morphine addiction_Homo sapiens_hsa050320.63415114
77MicroRNAs in cancer_Homo sapiens_hsa052060.62772235
78Oxytocin signaling pathway_Homo sapiens_hsa049210.60434698
79Long-term depression_Homo sapiens_hsa047300.59807714
80Circadian rhythm_Homo sapiens_hsa047100.59167909
81Insulin secretion_Homo sapiens_hsa049110.58939976
82GnRH signaling pathway_Homo sapiens_hsa049120.58404358
83Choline metabolism in cancer_Homo sapiens_hsa052310.57246812
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.56822609
85Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.54003070
86Calcium signaling pathway_Homo sapiens_hsa040200.51645768
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51482271
88Peroxisome_Homo sapiens_hsa041460.50445696
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50419555
90Basal cell carcinoma_Homo sapiens_hsa052170.49496606
91Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.48774605
92RNA polymerase_Homo sapiens_hsa030200.46727299
93mRNA surveillance pathway_Homo sapiens_hsa030150.46441951
94ErbB signaling pathway_Homo sapiens_hsa040120.43882192
95Endometrial cancer_Homo sapiens_hsa052130.41681859
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40484602
97Transcriptional misregulation in cancer_Homo sapiens_hsa052020.38739977
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38516523
99Retinol metabolism_Homo sapiens_hsa008300.36663193
100Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36181850

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