

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | opioid receptor signaling pathway (GO:0038003) | 9.97345510 |
| 2 | behavioral response to ethanol (GO:0048149) | 8.99680265 |
| 3 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 8.82579805 |
| 4 | adult feeding behavior (GO:0008343) | 8.36480469 |
| 5 | regulation of translational termination (GO:0006449) | 8.18703222 |
| 6 | regulation of acrosome reaction (GO:0060046) | 7.39067353 |
| 7 | regulation of protein glycosylation (GO:0060049) | 7.08347003 |
| 8 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 6.75316019 |
| 9 | positive regulation of cAMP-mediated signaling (GO:0043950) | 6.42971296 |
| 10 | glycerol ether metabolic process (GO:0006662) | 6.17149526 |
| 11 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 5.99068083 |
| 12 | thrombin receptor signaling pathway (GO:0070493) | 5.97863671 |
| 13 | DNA replication-dependent nucleosome assembly (GO:0006335) | 5.94594990 |
| 14 | DNA replication-dependent nucleosome organization (GO:0034723) | 5.94594990 |
| 15 | piRNA metabolic process (GO:0034587) | 5.94303713 |
| 16 | sphingosine metabolic process (GO:0006670) | 5.92666835 |
| 17 | ether metabolic process (GO:0018904) | 5.71044954 |
| 18 | diol metabolic process (GO:0034311) | 5.43934046 |
| 19 | sphingoid metabolic process (GO:0046519) | 5.22321618 |
| 20 | response to pheromone (GO:0019236) | 5.17166837 |
| 21 | notochord development (GO:0030903) | 4.99776130 |
| 22 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 4.97129887 |
| 23 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.91244568 |
| 24 | cellular response to ammonium ion (GO:0071242) | 4.67464027 |
| 25 | fat-soluble vitamin biosynthetic process (GO:0042362) | 4.53473926 |
| 26 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.39450978 |
| 27 | ncRNA catabolic process (GO:0034661) | 4.38986675 |
| 28 | mRNA cleavage (GO:0006379) | 4.24875097 |
| 29 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 4.24138899 |
| 30 | regulation of cAMP-mediated signaling (GO:0043949) | 4.10583595 |
| 31 | signal peptide processing (GO:0006465) | 4.10455088 |
| 32 | regulation of translational elongation (GO:0006448) | 4.04529864 |
| 33 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.85554266 |
| 34 | glomerular visceral epithelial cell development (GO:0072015) | 3.83728186 |
| 35 | cellular response to alkaloid (GO:0071312) | 3.80015438 |
| 36 | vitamin biosynthetic process (GO:0009110) | 3.69950431 |
| 37 | ribonucleoprotein complex disassembly (GO:0032988) | 3.66182626 |
| 38 | viral mRNA export from host cell nucleus (GO:0046784) | 3.65481975 |
| 39 | negative regulation of adenylate cyclase activity (GO:0007194) | 3.59121251 |
| 40 | L-fucose metabolic process (GO:0042354) | 3.50809808 |
| 41 | L-fucose catabolic process (GO:0042355) | 3.50809808 |
| 42 | fucose catabolic process (GO:0019317) | 3.50809808 |
| 43 | negative regulation of glycoprotein metabolic process (GO:1903019) | 3.48079323 |
| 44 | negative regulation of cyclase activity (GO:0031280) | 3.44187001 |
| 45 | DNA deamination (GO:0045006) | 3.41836541 |
| 46 | N-terminal protein amino acid acetylation (GO:0006474) | 3.40263480 |
| 47 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.37547917 |
| 48 | glomerular epithelial cell development (GO:0072310) | 3.32502529 |
| 49 | negative regulation of lyase activity (GO:0051350) | 3.32319288 |
| 50 | coenzyme catabolic process (GO:0009109) | 3.29575690 |
| 51 | negative regulation of cell-matrix adhesion (GO:0001953) | 3.28780086 |
| 52 | signal complex assembly (GO:0007172) | 3.27897397 |
| 53 | cornea development in camera-type eye (GO:0061303) | 3.21600228 |
| 54 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.20785270 |
| 55 | fat-soluble vitamin catabolic process (GO:0042363) | 3.17932223 |
| 56 | vitamin catabolic process (GO:0009111) | 3.17932223 |
| 57 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 3.16838093 |
| 58 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.14682793 |
| 59 | positive regulation of fatty acid transport (GO:2000193) | 3.09122253 |
| 60 | pyrimidine dimer repair (GO:0006290) | 3.07852146 |
| 61 | positive regulation of icosanoid secretion (GO:0032305) | 3.05362361 |
| 62 | polyol biosynthetic process (GO:0046173) | 3.02066669 |
| 63 | glycosphingolipid metabolic process (GO:0006687) | 3.02038380 |
| 64 | thyroid hormone generation (GO:0006590) | 3.01843187 |
| 65 | neuronal action potential (GO:0019228) | 3.01512031 |
| 66 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.99862192 |
| 67 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 2.99554841 |
| 68 | negative regulation of exocytosis (GO:0045920) | 2.95441563 |
| 69 | regulation of female receptivity (GO:0045924) | 2.93504420 |
| 70 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.89000934 |
| 71 | omega-hydroxylase P450 pathway (GO:0097267) | 2.88359562 |
| 72 | aldehyde catabolic process (GO:0046185) | 2.87837289 |
| 73 | indolalkylamine metabolic process (GO:0006586) | 2.86717776 |
| 74 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.86426936 |
| 75 | negative regulation of cAMP biosynthetic process (GO:0030818) | 2.85677620 |
| 76 | negative regulation of macrophage differentiation (GO:0045650) | 2.85399641 |
| 77 | thyroid hormone metabolic process (GO:0042403) | 2.81743839 |
| 78 | membrane depolarization during action potential (GO:0086010) | 2.80783925 |
| 79 | positive regulation of gluconeogenesis (GO:0045722) | 2.80083477 |
| 80 | quinone biosynthetic process (GO:1901663) | 2.79994697 |
| 81 | GPI anchor metabolic process (GO:0006505) | 2.79798930 |
| 82 | cellular response to ATP (GO:0071318) | 2.79793283 |
| 83 | glycolipid metabolic process (GO:0006664) | 2.78186880 |
| 84 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.78114006 |
| 85 | left/right axis specification (GO:0070986) | 2.77495831 |
| 86 | negative regulation of cyclic nucleotide biosynthetic process (GO:0030803) | 2.76772046 |
| 87 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.74590050 |
| 88 | replication fork processing (GO:0031297) | 2.66910403 |
| 89 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.66405575 |
| 90 | membrane lipid metabolic process (GO:0006643) | 2.65819061 |
| 91 | wound healing, spreading of epidermal cells (GO:0035313) | 2.63871630 |
| 92 | negative regulation of nucleotide biosynthetic process (GO:0030809) | 2.63460440 |
| 93 | negative regulation of purine nucleotide biosynthetic process (GO:1900372) | 2.63460440 |
| 94 | response to caffeine (GO:0031000) | 2.63393671 |
| 95 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.62399866 |
| 96 | response to morphine (GO:0043278) | 2.61877233 |
| 97 | liposaccharide metabolic process (GO:1903509) | 2.61447983 |
| 98 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 13.7191151 |
| 99 | negative regulation of cAMP-mediated signaling (GO:0043951) | 10.8156873 |
| 100 | ether lipid metabolic process (GO:0046485) | 10.3193439 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.56333175 |
| 2 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.30280057 |
| 3 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.22063355 |
| 4 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.85653055 |
| 5 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 2.85653055 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.79548821 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.74989427 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.74020255 |
| 9 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.71785473 |
| 10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.65128466 |
| 11 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.64629598 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.46083639 |
| 13 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.40492343 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.38342803 |
| 15 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.31789852 |
| 16 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.20694824 |
| 17 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.17295891 |
| 18 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.14056513 |
| 19 | RXR_22108803_ChIP-Seq_LS180_Human | 2.02692740 |
| 20 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.94252485 |
| 21 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.91729088 |
| 22 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.90166480 |
| 23 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.90166480 |
| 24 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.90150774 |
| 25 | FUS_26573619_Chip-Seq_HEK293_Human | 1.79871063 |
| 26 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.75438389 |
| 27 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.74901852 |
| 28 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.73051993 |
| 29 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.73021384 |
| 30 | TCF4_23295773_ChIP-Seq_U87_Human | 1.71897893 |
| 31 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.71043419 |
| 32 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.70535823 |
| 33 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.69040048 |
| 34 | STAT3_23295773_ChIP-Seq_U87_Human | 1.65410937 |
| 35 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.65077604 |
| 36 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.62162627 |
| 37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.61247928 |
| 38 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.60381789 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.54953282 |
| 40 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.50348399 |
| 41 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.48536863 |
| 42 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.47044896 |
| 43 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.47044896 |
| 44 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.44358201 |
| 45 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.43773941 |
| 46 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.42481460 |
| 47 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40682364 |
| 48 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.40571820 |
| 49 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.37298525 |
| 50 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.36979248 |
| 51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.35277764 |
| 52 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.34652146 |
| 53 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.30244764 |
| 54 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.28894461 |
| 55 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.27139263 |
| 56 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.25863880 |
| 57 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.25762709 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25162213 |
| 59 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.24968882 |
| 60 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.23364096 |
| 61 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.22606330 |
| 62 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.22550375 |
| 63 | EWS_26573619_Chip-Seq_HEK293_Human | 1.22459815 |
| 64 | AR_25329375_ChIP-Seq_VCAP_Human | 1.22407308 |
| 65 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.20492924 |
| 66 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.20312713 |
| 67 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.19096397 |
| 68 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17815378 |
| 69 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.17782374 |
| 70 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.17053303 |
| 71 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.16761030 |
| 72 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.16732175 |
| 73 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15430545 |
| 74 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.14017912 |
| 75 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.12107358 |
| 76 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.10061301 |
| 77 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.09019586 |
| 78 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.08822863 |
| 79 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.08049024 |
| 80 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.07768976 |
| 81 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.07047573 |
| 82 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.07043114 |
| 83 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.06990816 |
| 84 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.06907789 |
| 85 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06119833 |
| 86 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.06060520 |
| 87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.05981352 |
| 88 | TP53_16413492_ChIP-PET_HCT116_Human | 1.05474508 |
| 89 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.04630726 |
| 90 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.03938269 |
| 91 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03605809 |
| 92 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.03539594 |
| 93 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03286134 |
| 94 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.02560423 |
| 95 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02477351 |
| 96 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.01135198 |
| 97 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.00213373 |
| 98 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.99380165 |
| 99 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99151956 |
| 100 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98361040 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009278_abnormal_bone_marrow | 5.72783341 |
| 2 | MP0009780_abnormal_chondrocyte_physiolo | 5.40552520 |
| 3 | MP0002876_abnormal_thyroid_physiology | 5.07264114 |
| 4 | MP0005360_urolithiasis | 4.83579577 |
| 5 | MP0001968_abnormal_touch/_nociception | 3.81668432 |
| 6 | MP0005503_abnormal_tendon_morphology | 3.14176602 |
| 7 | MP0001501_abnormal_sleep_pattern | 3.12680588 |
| 8 | MP0003880_abnormal_central_pattern | 3.08899849 |
| 9 | MP0009764_decreased_sensitivity_to | 3.03141270 |
| 10 | MP0003941_abnormal_skin_development | 2.82246636 |
| 11 | MP0005646_abnormal_pituitary_gland | 2.69605609 |
| 12 | MP0003195_calcinosis | 2.59353613 |
| 13 | MP0006035_abnormal_mitochondrial_morpho | 2.30889665 |
| 14 | MP0003045_fibrosis | 2.28453967 |
| 15 | MP0000569_abnormal_digit_pigmentation | 2.23752543 |
| 16 | MP0001664_abnormal_digestion | 2.22470244 |
| 17 | MP0000678_abnormal_parathyroid_gland | 2.16942643 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 2.08127882 |
| 19 | MP0001545_abnormal_hematopoietic_system | 2.01990677 |
| 20 | MP0005397_hematopoietic_system_phenotyp | 2.01990677 |
| 21 | MP0003646_muscle_fatigue | 2.01533261 |
| 22 | MP0004147_increased_porphyrin_level | 2.00345736 |
| 23 | MP0000566_synostosis | 1.96058246 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.85760672 |
| 25 | MP0002249_abnormal_larynx_morphology | 1.73810434 |
| 26 | MP0000681_abnormal_thyroid_gland | 1.73607084 |
| 27 | MP0009046_muscle_twitch | 1.62197362 |
| 28 | MP0003633_abnormal_nervous_system | 1.54009058 |
| 29 | MP0003183_abnormal_peptide_metabolism | 1.51515430 |
| 30 | MP0006054_spinal_hemorrhage | 1.47689657 |
| 31 | MP0002733_abnormal_thermal_nociception | 1.47324135 |
| 32 | MP0002168_other_aberrant_phenotype | 1.39928493 |
| 33 | MP0009745_abnormal_behavioral_response | 1.36769663 |
| 34 | MP0010234_abnormal_vibrissa_follicle | 1.34718487 |
| 35 | MP0009333_abnormal_splenocyte_physiolog | 1.33915275 |
| 36 | MP0000015_abnormal_ear_pigmentation | 1.32759070 |
| 37 | MP0002272_abnormal_nervous_system | 1.30559552 |
| 38 | MP0003959_abnormal_lean_body | 1.26093587 |
| 39 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22793484 |
| 40 | MP0004782_abnormal_surfactant_physiolog | 1.17280908 |
| 41 | MP0003638_abnormal_response/metabolism_ | 1.15589020 |
| 42 | MP0008872_abnormal_physiological_respon | 1.12377312 |
| 43 | MP0005408_hypopigmentation | 1.11294152 |
| 44 | MP0002796_impaired_skin_barrier | 1.09964304 |
| 45 | MP0005075_abnormal_melanosome_morpholog | 1.09221516 |
| 46 | MP0001486_abnormal_startle_reflex | 1.08865209 |
| 47 | MP0001324_abnormal_eye_pigmentation | 1.07849788 |
| 48 | MP0009053_abnormal_anal_canal | 1.07011542 |
| 49 | MP0003937_abnormal_limbs/digits/tail_de | 1.06714120 |
| 50 | MP0009765_abnormal_xenobiotic_induced | 1.06166367 |
| 51 | MP0008058_abnormal_DNA_repair | 1.05678176 |
| 52 | MP0003191_abnormal_cellular_cholesterol | 1.04355973 |
| 53 | MP0000230_abnormal_systemic_arterial | 0.97651425 |
| 54 | MP0001970_abnormal_pain_threshold | 0.96690062 |
| 55 | MP0002148_abnormal_hypersensitivity_rea | 0.96588766 |
| 56 | MP0003950_abnormal_plasma_membrane | 0.96293862 |
| 57 | MP0005310_abnormal_salivary_gland | 0.94793463 |
| 58 | MP0001919_abnormal_reproductive_system | 0.92652539 |
| 59 | MP0006072_abnormal_retinal_apoptosis | 0.90856011 |
| 60 | MP0000049_abnormal_middle_ear | 0.90594100 |
| 61 | MP0002693_abnormal_pancreas_physiology | 0.89912034 |
| 62 | MP0003631_nervous_system_phenotype | 0.87720926 |
| 63 | MP0003868_abnormal_feces_composition | 0.87186445 |
| 64 | MP0008875_abnormal_xenobiotic_pharmacok | 0.85146750 |
| 65 | MP0002971_abnormal_brown_adipose | 0.77381200 |
| 66 | MP0005395_other_phenotype | 0.76467066 |
| 67 | MP0001881_abnormal_mammary_gland | 0.75431626 |
| 68 | MP0003879_abnormal_hair_cell | 0.71055414 |
| 69 | MP0008057_abnormal_DNA_replication | 0.69797613 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.65829710 |
| 71 | MP0002557_abnormal_social/conspecific_i | 0.65041764 |
| 72 | MP0001529_abnormal_vocalization | 0.65018833 |
| 73 | MP0000358_abnormal_cell_content/ | 0.64808018 |
| 74 | MP0005195_abnormal_posterior_eye | 0.63682346 |
| 75 | MP0005334_abnormal_fat_pad | 0.63321028 |
| 76 | MP0008789_abnormal_olfactory_epithelium | 0.62500157 |
| 77 | MP0005085_abnormal_gallbladder_physiolo | 0.62251623 |
| 78 | MP0000685_abnormal_immune_system | 0.61677664 |
| 79 | MP0005083_abnormal_biliary_tract | 0.60999578 |
| 80 | MP0008775_abnormal_heart_ventricle | 0.60883318 |
| 81 | MP0002736_abnormal_nociception_after | 0.57911806 |
| 82 | MP0006036_abnormal_mitochondrial_physio | 0.56513829 |
| 83 | MP0004085_abnormal_heartbeat | 0.56351184 |
| 84 | MP0000749_muscle_degeneration | 0.56113242 |
| 85 | MP0002229_neurodegeneration | 0.55375644 |
| 86 | MP0005197_abnormal_uvea_morphology | 0.54483352 |
| 87 | MP0002063_abnormal_learning/memory/cond | 0.53964667 |
| 88 | MP0002932_abnormal_joint_morphology | 0.53202248 |
| 89 | MP0004858_abnormal_nervous_system | 0.52177438 |
| 90 | MP0006276_abnormal_autonomic_nervous | 0.51739721 |
| 91 | MP0005174_abnormal_tail_pigmentation | 0.50594193 |
| 92 | MP0001765_abnormal_ion_homeostasis | 0.49690430 |
| 93 | MP0005167_abnormal_blood-brain_barrier | 0.48598528 |
| 94 | MP0001756_abnormal_urination | 0.47952399 |
| 95 | MP0005636_abnormal_mineral_homeostasis | 0.47826660 |
| 96 | MP0002064_seizures | 0.47363480 |
| 97 | MP0010771_integument_phenotype | 0.44871247 |
| 98 | MP0002572_abnormal_emotion/affect_behav | 0.44717957 |
| 99 | MP0002752_abnormal_somatic_nervous | 0.44488841 |
| 100 | MP0005464_abnormal_platelet_physiology | 0.44373019 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Volvulus (HP:0002580) | 6.28483145 |
| 2 | Intestinal atresia (HP:0011100) | 6.08816074 |
| 3 | Pancreatic islet-cell hyperplasia (HP:0004510) | 5.61459426 |
| 4 | Abnormality of the aortic arch (HP:0012303) | 5.47641095 |
| 5 | Broad alveolar ridges (HP:0000187) | 5.00248575 |
| 6 | Poor head control (HP:0002421) | 4.48276664 |
| 7 | Large for gestational age (HP:0001520) | 4.47232357 |
| 8 | Thickened helices (HP:0000391) | 4.25623835 |
| 9 | Mesangial abnormality (HP:0001966) | 4.22128674 |
| 10 | Focal motor seizures (HP:0011153) | 4.12177305 |
| 11 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.98747729 |
| 12 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.98747729 |
| 13 | Oligodontia (HP:0000677) | 3.73080026 |
| 14 | Agitation (HP:0000713) | 3.67445532 |
| 15 | Gaze-evoked nystagmus (HP:0000640) | 3.56908955 |
| 16 | Congenital ichthyosiform erythroderma (HP:0007431) | 3.32787952 |
| 17 | Abnormality of the ileum (HP:0001549) | 3.25687790 |
| 18 | Hypoproteinemia (HP:0003075) | 3.21934488 |
| 19 | Tubular atrophy (HP:0000092) | 3.19039672 |
| 20 | Neonatal respiratory distress (HP:0002643) | 3.13130481 |
| 21 | Type II lissencephaly (HP:0007260) | 2.92662666 |
| 22 | Gastrointestinal atresia (HP:0002589) | 2.91639836 |
| 23 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.87276049 |
| 24 | Large eyes (HP:0001090) | 2.85146666 |
| 25 | Abnormality of the columella (HP:0009929) | 2.84444703 |
| 26 | Cerebellar dysplasia (HP:0007033) | 2.72595604 |
| 27 | Progressive inability to walk (HP:0002505) | 2.72340633 |
| 28 | Ectropion (HP:0000656) | 2.62411313 |
| 29 | Abnormality of macular pigmentation (HP:0008002) | 2.60901597 |
| 30 | Abnormality of the alveolar ridges (HP:0006477) | 2.56546113 |
| 31 | Abolished electroretinogram (ERG) (HP:0000550) | 2.56331562 |
| 32 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.55743433 |
| 33 | Focal seizures (HP:0007359) | 2.55583054 |
| 34 | High anterior hairline (HP:0009890) | 2.43690723 |
| 35 | Keratoconus (HP:0000563) | 2.42544042 |
| 36 | Increased corneal curvature (HP:0100692) | 2.42544042 |
| 37 | Myositis (HP:0100614) | 2.41647224 |
| 38 | Attenuation of retinal blood vessels (HP:0007843) | 2.38646089 |
| 39 | Hyperpituitarism (HP:0010514) | 2.38295034 |
| 40 | Tented upper lip vermilion (HP:0010804) | 2.36810801 |
| 41 | Optic nerve hypoplasia (HP:0000609) | 2.32569978 |
| 42 | 3-Methylglutaconic aciduria (HP:0003535) | 2.28185151 |
| 43 | Central scotoma (HP:0000603) | 2.27407396 |
| 44 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.25807651 |
| 45 | Abnormality of B cell number (HP:0010975) | 2.22202726 |
| 46 | Long nose (HP:0003189) | 2.20559538 |
| 47 | Scotoma (HP:0000575) | 2.20553357 |
| 48 | Orchitis (HP:0100796) | 2.20281189 |
| 49 | Pendular nystagmus (HP:0012043) | 2.19163034 |
| 50 | Lissencephaly (HP:0001339) | 2.18822964 |
| 51 | Autoimmune hemolytic anemia (HP:0001890) | 2.16808963 |
| 52 | Congenital stationary night blindness (HP:0007642) | 2.14275003 |
| 53 | Restlessness (HP:0000711) | 2.13644061 |
| 54 | Broad-based gait (HP:0002136) | 2.09327532 |
| 55 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.06746649 |
| 56 | Hypoplasia of the brainstem (HP:0002365) | 2.06746649 |
| 57 | Chromsome breakage (HP:0040012) | 2.06297729 |
| 58 | Non-midline cleft lip (HP:0100335) | 2.06217883 |
| 59 | Dialeptic seizures (HP:0011146) | 2.04385411 |
| 60 | Poor speech (HP:0002465) | 2.01097699 |
| 61 | Thyroid-stimulating hormone excess (HP:0002925) | 11.6877380 |
| 62 | Hypoplasia of the pons (HP:0012110) | 1.96831675 |
| 63 | Supernumerary spleens (HP:0009799) | 1.95738814 |
| 64 | Methylmalonic aciduria (HP:0012120) | 1.94943703 |
| 65 | Abnormality of midbrain morphology (HP:0002418) | 1.90477134 |
| 66 | Molar tooth sign on MRI (HP:0002419) | 1.90477134 |
| 67 | Pancreatic cysts (HP:0001737) | 1.90212341 |
| 68 | Inability to walk (HP:0002540) | 1.89696963 |
| 69 | Ileus (HP:0002595) | 1.83059553 |
| 70 | Neoplasm of the lung (HP:0100526) | 1.82489902 |
| 71 | Dysdiadochokinesis (HP:0002075) | 1.82058681 |
| 72 | Generalized tonic-clonic seizures (HP:0002069) | 1.81464931 |
| 73 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.80294228 |
| 74 | Severe visual impairment (HP:0001141) | 1.80145028 |
| 75 | Facial diplegia (HP:0001349) | 1.79106512 |
| 76 | Hypothermia (HP:0002045) | 1.78908734 |
| 77 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.78638677 |
| 78 | Median cleft lip (HP:0000161) | 1.78330198 |
| 79 | Hyperglycinuria (HP:0003108) | 1.78189654 |
| 80 | Nonprogressive disorder (HP:0003680) | 1.77981529 |
| 81 | Postaxial foot polydactyly (HP:0001830) | 1.75925135 |
| 82 | Neoplasm of the respiratory system (HP:0100606) | 1.75470111 |
| 83 | Abnormality of the pons (HP:0007361) | 1.75081499 |
| 84 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.73995741 |
| 85 | Arthropathy (HP:0003040) | 1.72909102 |
| 86 | B lymphocytopenia (HP:0010976) | 1.72486861 |
| 87 | Asplenia (HP:0001746) | 1.70655567 |
| 88 | Pancreatic fibrosis (HP:0100732) | 1.70232122 |
| 89 | Embryonal renal neoplasm (HP:0011794) | 1.68162487 |
| 90 | Depressed nasal tip (HP:0000437) | 1.68150649 |
| 91 | Decreased circulating renin level (HP:0003351) | 1.68011848 |
| 92 | Muscular dystrophy (HP:0003560) | 1.67559389 |
| 93 | Testicular neoplasm (HP:0010788) | 1.66277142 |
| 94 | Goiter (HP:0000853) | 1.65145132 |
| 95 | Ketoacidosis (HP:0001993) | 1.63285792 |
| 96 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.61675311 |
| 97 | Hamartoma (HP:0010566) | 1.61496836 |
| 98 | Abnormal albumin level (HP:0012116) | 1.60881801 |
| 99 | Hypoalbuminemia (HP:0003073) | 1.60881801 |
| 100 | Hyperventilation (HP:0002883) | 1.60350571 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 9.45809907 |
| 2 | FRK | 5.10075446 |
| 3 | ERN1 | 3.44495664 |
| 4 | PINK1 | 2.83241829 |
| 5 | MAP4K2 | 2.82230344 |
| 6 | ADRBK1 | 2.58852805 |
| 7 | IRAK3 | 2.01909156 |
| 8 | CSNK1G1 | 2.00427873 |
| 9 | GRK7 | 1.97620815 |
| 10 | CSNK1G3 | 1.95221069 |
| 11 | ACVR1B | 1.83777444 |
| 12 | PRKCE | 1.79806340 |
| 13 | CSNK1A1L | 1.79716261 |
| 14 | FES | 1.70144491 |
| 15 | PRKCG | 1.68867916 |
| 16 | PNCK | 1.65328829 |
| 17 | GRK1 | 1.63727505 |
| 18 | IRAK1 | 1.59207753 |
| 19 | TGFBR1 | 1.52724313 |
| 20 | CSNK1G2 | 1.51608557 |
| 21 | WNK3 | 1.43379363 |
| 22 | BMPR1B | 1.30416431 |
| 23 | NUAK1 | 1.28141648 |
| 24 | MAPK11 | 1.25978331 |
| 25 | PLK2 | 1.23886989 |
| 26 | DYRK3 | 1.22745451 |
| 27 | MKNK1 | 1.21755583 |
| 28 | FER | 1.21404918 |
| 29 | TYRO3 | 1.12717121 |
| 30 | TAOK3 | 1.08316470 |
| 31 | MKNK2 | 1.03023252 |
| 32 | MAP3K9 | 1.02982530 |
| 33 | GRK5 | 1.01151131 |
| 34 | OXSR1 | 0.99401373 |
| 35 | PRKCI | 0.97370185 |
| 36 | NEK1 | 0.96411961 |
| 37 | FLT3 | 0.95811647 |
| 38 | TEC | 0.91591745 |
| 39 | EIF2AK3 | 0.91397508 |
| 40 | MARK1 | 0.90863062 |
| 41 | STK38 | 0.90435494 |
| 42 | TNIK | 0.84873747 |
| 43 | CLK1 | 0.84602381 |
| 44 | TESK1 | 0.82687343 |
| 45 | TIE1 | 0.81985029 |
| 46 | ZAK | 0.78616609 |
| 47 | CAMK2A | 0.72629068 |
| 48 | MST4 | 0.72106626 |
| 49 | CAMK1 | 0.69250156 |
| 50 | MAPK13 | 0.61467887 |
| 51 | CSNK1A1 | 0.60163939 |
| 52 | DYRK1A | 0.57876583 |
| 53 | MATK | 0.56564532 |
| 54 | ERBB2 | 0.49444286 |
| 55 | BCR | 0.48358749 |
| 56 | BMPR2 | 0.47296240 |
| 57 | PRKCA | 0.45409716 |
| 58 | STK39 | 0.43857842 |
| 59 | PTK2B | 0.42948396 |
| 60 | CAMK1G | 0.42758462 |
| 61 | NEK9 | 0.40416487 |
| 62 | MAPKAPK5 | 0.40006418 |
| 63 | ITK | 0.39416457 |
| 64 | ATR | 0.38971473 |
| 65 | CSNK1E | 0.38133128 |
| 66 | PRKCB | 0.38114454 |
| 67 | INSRR | 0.37991278 |
| 68 | KIT | 0.36211482 |
| 69 | CASK | 0.36202400 |
| 70 | STK3 | 0.33829000 |
| 71 | MAPKAPK3 | 0.33377122 |
| 72 | TRIM28 | 0.30670194 |
| 73 | VRK1 | 0.30586734 |
| 74 | PRKACA | 0.29549227 |
| 75 | NME1 | 0.29507662 |
| 76 | IKBKB | 0.27922350 |
| 77 | MOS | 0.26381745 |
| 78 | CAMK4 | 0.25616020 |
| 79 | PRKACG | 0.25406792 |
| 80 | WNK4 | 0.24543481 |
| 81 | BTK | 0.23682003 |
| 82 | TAF1 | 0.23389680 |
| 83 | CSNK1D | 0.23374620 |
| 84 | BRAF | 0.22021400 |
| 85 | ABL1 | 0.20954464 |
| 86 | MAPK1 | 0.20745359 |
| 87 | IKBKE | 0.19584513 |
| 88 | PAK3 | 0.19138749 |
| 89 | PLK3 | 0.18754235 |
| 90 | VRK2 | 0.18380436 |
| 91 | PRKG1 | 0.18231930 |
| 92 | DAPK2 | 0.18167606 |
| 93 | SGK1 | 0.17716371 |
| 94 | TNK2 | 0.17290437 |
| 95 | RPS6KA3 | 0.15953642 |
| 96 | CSF1R | 0.15149250 |
| 97 | MAP3K12 | 0.15142334 |
| 98 | PHKG2 | 0.14471766 |
| 99 | PHKG1 | 0.14471766 |
| 100 | DAPK1 | 0.13675776 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.29225565 |
| 2 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 3.21082186 |
| 3 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.86815061 |
| 4 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.75505346 |
| 5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.73075560 |
| 6 | Phototransduction_Homo sapiens_hsa04744 | 2.61197723 |
| 7 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.58523403 |
| 8 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.40291786 |
| 9 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.20696675 |
| 10 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.11396061 |
| 11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.08879387 |
| 12 | Morphine addiction_Homo sapiens_hsa05032 | 2.07746834 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.03482314 |
| 14 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.98023748 |
| 15 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.92689035 |
| 16 | ABC transporters_Homo sapiens_hsa02010 | 1.88145898 |
| 17 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.85311674 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.83915965 |
| 19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.76320104 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.74651114 |
| 21 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.70402088 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.70051160 |
| 23 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.62858344 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.61930547 |
| 25 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.56953388 |
| 26 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.53343049 |
| 27 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.52583992 |
| 28 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.49351296 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.41596846 |
| 30 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.36243590 |
| 31 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.34026346 |
| 32 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.30986727 |
| 33 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.30977769 |
| 34 | Taste transduction_Homo sapiens_hsa04742 | 1.29611120 |
| 35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.23814498 |
| 36 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.22682898 |
| 37 | Proteasome_Homo sapiens_hsa03050 | 1.22191214 |
| 38 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.21562158 |
| 39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.18050088 |
| 40 | Retinol metabolism_Homo sapiens_hsa00830 | 1.15456826 |
| 41 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.12299191 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.11395667 |
| 43 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.09039544 |
| 44 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.07399407 |
| 45 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.05377810 |
| 46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.05153809 |
| 47 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.04767391 |
| 48 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.04387942 |
| 49 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.02766670 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.96569642 |
| 51 | Sulfur relay system_Homo sapiens_hsa04122 | 0.95826356 |
| 52 | RNA degradation_Homo sapiens_hsa03018 | 0.90837026 |
| 53 | Mineral absorption_Homo sapiens_hsa04978 | 0.89047242 |
| 54 | Parkinsons disease_Homo sapiens_hsa05012 | 0.83880746 |
| 55 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.81908240 |
| 56 | Salivary secretion_Homo sapiens_hsa04970 | 0.78394567 |
| 57 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.77676080 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.77587640 |
| 59 | Legionellosis_Homo sapiens_hsa05134 | 0.74345151 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.74310661 |
| 61 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.72650164 |
| 62 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.69594010 |
| 63 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.68326140 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68124159 |
| 65 | Histidine metabolism_Homo sapiens_hsa00340 | 0.67132412 |
| 66 | Circadian entrainment_Homo sapiens_hsa04713 | 0.66307011 |
| 67 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.65386956 |
| 68 | RNA transport_Homo sapiens_hsa03013 | 0.64510425 |
| 69 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.63075213 |
| 70 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.61583581 |
| 71 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.60915312 |
| 72 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60335494 |
| 73 | RNA polymerase_Homo sapiens_hsa03020 | 0.60269674 |
| 74 | Alzheimers disease_Homo sapiens_hsa05010 | 0.59645481 |
| 75 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.59140697 |
| 76 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.56219926 |
| 77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.55738284 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.54413928 |
| 79 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.54223246 |
| 80 | GABAergic synapse_Homo sapiens_hsa04727 | 0.54020766 |
| 81 | Asthma_Homo sapiens_hsa05310 | 0.47755189 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.45799996 |
| 83 | Homologous recombination_Homo sapiens_hsa03440 | 0.44511795 |
| 84 | Long-term depression_Homo sapiens_hsa04730 | 0.44423336 |
| 85 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.44223783 |
| 86 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.43593652 |
| 87 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.43089971 |
| 88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.43072455 |
| 89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41475442 |
| 90 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.41239194 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.39626270 |
| 92 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.39269870 |
| 93 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.38166771 |
| 94 | Huntingtons disease_Homo sapiens_hsa05016 | 0.37424807 |
| 95 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.37017216 |
| 96 | Allograft rejection_Homo sapiens_hsa05330 | 0.36701394 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.36262718 |
| 98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.36224676 |
| 99 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.34055397 |
| 100 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.33344798 |

