VPS26B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.98339180
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.62203804
3locomotory exploration behavior (GO:0035641)5.34384206
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.11660553
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.00450471
6layer formation in cerebral cortex (GO:0021819)4.98473870
7vocalization behavior (GO:0071625)4.86637185
8synaptic vesicle exocytosis (GO:0016079)4.79311974
9synaptic vesicle docking involved in exocytosis (GO:0016081)4.68757290
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.62778617
11negative regulation of erythrocyte differentiation (GO:0045647)4.52610661
12regulation of synaptic vesicle exocytosis (GO:2000300)4.52302502
13glutamate secretion (GO:0014047)4.51000834
14positive regulation of synapse maturation (GO:0090129)4.41746396
15regulation of glutamate receptor signaling pathway (GO:1900449)4.40488072
16regulation of synapse structural plasticity (GO:0051823)4.30018390
17protein localization to synapse (GO:0035418)4.27073984
18exploration behavior (GO:0035640)4.21108232
19activation of protein kinase A activity (GO:0034199)4.09096111
20sodium ion export (GO:0071436)4.08857897
21dendritic spine morphogenesis (GO:0060997)3.98672118
22regulation of long-term neuronal synaptic plasticity (GO:0048169)3.95171506
23neurotransmitter secretion (GO:0007269)3.95162333
24proline transport (GO:0015824)3.95096014
25regulation of synaptic vesicle transport (GO:1902803)3.86418401
26regulation of neuronal synaptic plasticity (GO:0048168)3.85300268
27dendrite morphogenesis (GO:0048813)3.75068880
28cellular potassium ion homeostasis (GO:0030007)3.74928138
29neuron cell-cell adhesion (GO:0007158)3.70991681
30ionotropic glutamate receptor signaling pathway (GO:0035235)3.67558868
31cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.54692718
32cell communication by electrical coupling (GO:0010644)3.54064040
33neurotransmitter-gated ion channel clustering (GO:0072578)3.53539137
34G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.51600412
35establishment of nucleus localization (GO:0040023)3.50668997
36positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.47146515
37protein localization to endosome (GO:0036010)3.44918257
38neuromuscular process controlling balance (GO:0050885)3.40912024
39cerebellar Purkinje cell layer development (GO:0021680)3.39257367
40glutamate receptor signaling pathway (GO:0007215)3.35864758
41neuron recognition (GO:0008038)3.34576639
42regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.34300680
43innervation (GO:0060384)3.33738513
44regulation of dendritic spine morphogenesis (GO:0061001)3.32171530
45negative regulation of microtubule polymerization (GO:0031115)3.30218404
46synaptic transmission, glutamatergic (GO:0035249)3.29260405
47cerebellar granule cell differentiation (GO:0021707)3.28622910
48gamma-aminobutyric acid transport (GO:0015812)3.27439697
49regulation of ARF protein signal transduction (GO:0032012)3.25967828
50cell migration in hindbrain (GO:0021535)3.25575537
51positive regulation of membrane potential (GO:0045838)3.25128497
52long-term memory (GO:0007616)3.24599407
53regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.24111144
54neuronal action potential propagation (GO:0019227)3.22390321
55membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.18819992
56cerebellar Purkinje cell differentiation (GO:0021702)3.16885985
57clathrin coat assembly (GO:0048268)3.16807415
58axonal fasciculation (GO:0007413)3.16765747
59positive regulation of dendritic spine morphogenesis (GO:0061003)3.16234511
60alanine transport (GO:0032328)3.10749047
61regulation of excitatory postsynaptic membrane potential (GO:0060079)3.10078367
62regulation of synaptic plasticity (GO:0048167)3.04928893
63neuron-neuron synaptic transmission (GO:0007270)3.03981826
64Golgi transport vesicle coating (GO:0048200)3.02178157
65COPI coating of Golgi vesicle (GO:0048205)3.02178157
66postsynaptic membrane organization (GO:0001941)3.00996581
67retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.00904186
68negative regulation of cell size (GO:0045792)2.96830494
69pyrimidine nucleobase catabolic process (GO:0006208)2.96555621
70cellular response to catecholamine stimulus (GO:0071870)2.95568262
71cellular response to monoamine stimulus (GO:0071868)2.95568262
72proline biosynthetic process (GO:0006561)2.95238270
73regulation of ARF GTPase activity (GO:0032312)2.93760302
74mannose metabolic process (GO:0006013)2.93545266
75regulation of clathrin-mediated endocytosis (GO:2000369)2.92949783
76organelle transport along microtubule (GO:0072384)2.92747140
77regulation of postsynaptic membrane potential (GO:0060078)2.92454400
78vesicle transport along microtubule (GO:0047496)2.92028526
79neuronal ion channel clustering (GO:0045161)2.91651554
80cytoskeletal anchoring at plasma membrane (GO:0007016)2.89372506
81positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.89004309
82neurotransmitter transport (GO:0006836)2.86891203
83regulation of synapse maturation (GO:0090128)2.86878690
84peptidyl-tyrosine autophosphorylation (GO:0038083)2.85651684
85positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.85606604
86prepulse inhibition (GO:0060134)2.85202727
87positive regulation of dendritic spine development (GO:0060999)2.84543142
88central nervous system projection neuron axonogenesis (GO:0021952)2.83994023
89cellular sodium ion homeostasis (GO:0006883)2.83794704
90regulation of early endosome to late endosome transport (GO:2000641)2.83464652
91dopamine receptor signaling pathway (GO:0007212)2.80337877
92negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.76837944
93regulation of neurotransmitter secretion (GO:0046928)2.76567639
94response to pheromone (GO:0019236)2.74332950
95auditory behavior (GO:0031223)2.74039669
96regulation of dendritic spine development (GO:0060998)2.73951564
97regulation of neurotransmitter levels (GO:0001505)2.73678778
98barbed-end actin filament capping (GO:0051016)2.73409846
99synapse assembly (GO:0007416)2.72024558
100intraspecies interaction between organisms (GO:0051703)2.69114098
101social behavior (GO:0035176)2.69114098
102regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68966649
103synapse organization (GO:0050808)2.68956986
104mating behavior (GO:0007617)2.68135737
105long-term synaptic potentiation (GO:0060291)2.67007762
106glial cell proliferation (GO:0014009)2.66956380
107L-amino acid import (GO:0043092)2.66945774
108membrane repolarization (GO:0086009)2.66635655
109chemosensory behavior (GO:0007635)2.66417329
110axon cargo transport (GO:0008088)2.66322828
111positive regulation of neurotransmitter transport (GO:0051590)2.66232682
112potassium ion import (GO:0010107)2.65629774
113dendritic spine organization (GO:0097061)2.65444808
114gamma-aminobutyric acid signaling pathway (GO:0007214)2.63930254
115regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.63540514
116positive regulation of protein dephosphorylation (GO:0035307)2.63497831
117neuromuscular process (GO:0050905)2.62754249
118amino acid import (GO:0043090)2.62233016
119neuromuscular process controlling posture (GO:0050884)2.62208889
120regulation of defense response to virus by virus (GO:0050690)2.61502579
121adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.58378448
122signal complex assembly (GO:0007172)2.58097235
123establishment of mitochondrion localization (GO:0051654)2.57919254
124cell-cell junction maintenance (GO:0045217)2.56125005
125regulation of NFAT protein import into nucleus (GO:0051532)2.56081270
126positive regulation of Rap GTPase activity (GO:0032854)2.55155393
127potassium ion homeostasis (GO:0055075)2.53014523
128mitochondrion transport along microtubule (GO:0047497)2.52400359
129establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.52400359
130protein retention in ER lumen (GO:0006621)2.50987192
131response to parathyroid hormone (GO:0071107)2.50351440
132protein targeting to plasma membrane (GO:0072661)2.48180910
133synaptic vesicle endocytosis (GO:0048488)2.44198674
134stress fiber assembly (GO:0043149)2.43880166
135regulation of extracellular matrix disassembly (GO:0010715)2.42373216
136regulation of amyloid precursor protein catabolic process (GO:1902991)2.40109527
137positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.39000648
138semaphorin-plexin signaling pathway (GO:0071526)2.33729669
139response to laminar fluid shear stress (GO:0034616)2.33029100
140negative regulation of cell killing (GO:0031342)2.31859924
141negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.31859924
142regulation of protein dephosphorylation (GO:0035304)2.30753411
143response to catecholamine (GO:0071869)2.27509388
144response to monoamine (GO:0071867)2.27509388
145positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.26616160
146actin filament polymerization (GO:0030041)2.26574059
147intracellular estrogen receptor signaling pathway (GO:0030520)2.26166572
148maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.25693315
149positive regulation of receptor recycling (GO:0001921)2.25499340
150negative regulation of dendrite morphogenesis (GO:0050774)2.23854115
151regulation of regulated secretory pathway (GO:1903305)2.21841169
152adherens junction assembly (GO:0034333)2.20277527
153regulation of glycogen (starch) synthase activity (GO:2000465)2.18106906
154regulation of Rap GTPase activity (GO:0032317)2.15075473
155cellular response to prostaglandin stimulus (GO:0071379)2.15025251
156regulation of beta-amyloid formation (GO:1902003)2.14480851

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.38163396
2THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.28226829
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.00626354
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00218893
5RARB_27405468_Chip-Seq_BRAIN_Mouse2.94658027
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.87566568
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.81006739
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.76446326
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.76446326
10DROSHA_22980978_ChIP-Seq_HELA_Human2.64536939
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.59025858
12EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.47491739
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46400271
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.42773949
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38283587
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38217381
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.36931428
18REST_21632747_ChIP-Seq_MESCs_Mouse2.33633054
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26010717
20VDR_21846776_ChIP-Seq_THP-1_Human2.25412241
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.24979354
22GBX2_23144817_ChIP-Seq_PC3_Human2.22452444
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.19400992
24ELK3_25401928_ChIP-Seq_HUVEC_Human2.19390247
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.17879494
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.17096885
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.16284360
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.15545389
29* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.11454781
30* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.11003795
31RACK7_27058665_Chip-Seq_MCF-7_Human2.06586840
32ESR2_21235772_ChIP-Seq_MCF-7_Human2.03899419
33ZNF274_21170338_ChIP-Seq_K562_Hela2.00091352
34MYC_22102868_ChIP-Seq_BL_Human1.99575728
35AR_21572438_ChIP-Seq_LNCaP_Human1.95649415
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.88375463
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.85731488
38TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.81332899
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.80686003
40RARG_19884340_ChIP-ChIP_MEFs_Mouse1.78946976
41KDM2B_26808549_Chip-Seq_K562_Human1.76985829
42NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.74152729
43NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.73571422
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.73181324
45EGR1_19374776_ChIP-ChIP_THP-1_Human1.71552747
46EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.65553385
47DNAJC2_21179169_ChIP-ChIP_NT2_Human1.62740819
48KDM2B_26808549_Chip-Seq_SUP-B15_Human1.61434942
49RING1B_27294783_Chip-Seq_ESCs_Mouse1.60234145
50ZFP281_27345836_Chip-Seq_ESCs_Mouse1.58098091
51KDM2B_26808549_Chip-Seq_DND41_Human1.56934244
52DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.55715462
53TP63_17297297_ChIP-ChIP_HaCaT_Human1.54178473
54SMC4_20622854_ChIP-Seq_HELA_Human1.52877566
55TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.49285581
56SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.48334660
57CTCF_27219007_Chip-Seq_ERYTHROID_Human1.47423427
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.43512583
59SA1_27219007_Chip-Seq_ERYTHROID_Human1.40430380
60VDR_24763502_ChIP-Seq_THP-1_Human1.40362790
61UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.38787287
62TET1_21451524_ChIP-Seq_MESCs_Mouse1.38693382
63SRY_22984422_ChIP-ChIP_TESTIS_Rat1.38498739
64TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.38140299
65WT1_25993318_ChIP-Seq_PODOCYTE_Human1.37894967
66TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.37232722
67CLOCK_20551151_ChIP-Seq_293T_Human1.35883657
68* KDM2B_26808549_Chip-Seq_JURKAT_Human1.34795748
69P68_20966046_ChIP-Seq_HELA_Human1.34718206
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.32982932
71ESR1_20079471_ChIP-ChIP_T-47D_Human1.29770157
72NR3C1_23031785_ChIP-Seq_PC12_Mouse1.28944891
73AR_19668381_ChIP-Seq_PC3_Human1.28685905
74CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28085784
75NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.26611516
76EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.25531257
77KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24465157
78SOX2_21211035_ChIP-Seq_LN229_Gbm1.21716614
79PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.21544345
80VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21267719
81PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21111223
82GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.20748358
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19065425
84PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.18651706
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18433601
86SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17082388
87RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.16746049
88KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16576347
89RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.16431735
90E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.15692350
91ESR1_15608294_ChIP-ChIP_MCF-7_Human1.15183534
92LXR_22292898_ChIP-Seq_THP-1_Human1.14896273
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14661246
94* RUNX1_22412390_ChIP-Seq_EML_Mouse1.13886707
95GATA1_19941826_ChIP-Seq_K562_Human1.13618401
96SMAD4_21799915_ChIP-Seq_A2780_Human1.12769006
97ZNF263_19887448_ChIP-Seq_K562_Human1.12511578
98RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10348402
99ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10036713
100YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08355346
101MAF_26560356_Chip-Seq_TH1_Human1.08347393
102SPI1_23127762_ChIP-Seq_K562_Human1.06431302
103CREB1_26743006_Chip-Seq_LNCaP_Human1.05559248
104SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04527528
105TP53_20018659_ChIP-ChIP_R1E_Mouse1.04170256
106GATA1_22383799_ChIP-Seq_G1ME_Mouse1.04015967
107* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03542204
108TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03019624
109* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.02879924
110* UTX_26944678_Chip-Seq_JUKART_Human1.02781409
111* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.02472051
112ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02220569
113SMAD4_21741376_ChIP-Seq_HESCs_Human1.02068604
114RUNX1_27514584_Chip-Seq_MCF-7_Human1.01504843
115RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00654539
116SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.00644696
117STAT6_21828071_ChIP-Seq_BEAS2B_Human0.99966026
118MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.99723950
119MAF_26560356_Chip-Seq_TH2_Human0.98710712
120KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.98386098
121OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98022822
122SCL_19346495_ChIP-Seq_HPC-7_Human0.97631795
123CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97195390
124CTCF_27219007_Chip-Seq_Bcells_Human0.96534244
125PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96453745
126ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.95759781
127TBX20_22328084_ChIP-Seq_HEART_Mouse0.95284062
128TBX20_22080862_ChIP-Seq_HEART_Mouse0.95284062
129* MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.95248057
130CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94965385
131AR_25329375_ChIP-Seq_VCAP_Human0.92193227
132RXR_22108803_ChIP-Seq_LS180_Human0.91412820
133* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90814693
134TP53_16413492_ChIP-PET_HCT116_Human0.90778112
135SMAD_19615063_ChIP-ChIP_OVARY_Human0.89918503
136TCF7_22412390_ChIP-Seq_EML_Mouse0.89485071
137ARNT_22903824_ChIP-Seq_MCF-7_Human0.89268238
138ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.89218672
139SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.89087162
140TRIM28_21343339_ChIP-Seq_HEK293_Human0.88484241
141AHR_22903824_ChIP-Seq_MCF-7_Human0.88011433
142SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.87416210
143ISL1_27105846_Chip-Seq_CPCs_Mouse0.87203981
144* SMAD3_21741376_ChIP-Seq_EPCs_Human0.87180864
145P53_22127205_ChIP-Seq_FIBROBLAST_Human0.86796980
146CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.86522718
147CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.85878533
148TET1_21490601_ChIP-Seq_MESCs_Mouse0.85813523
149TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.84270061

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.65744759
2MP0003880_abnormal_central_pattern3.99940608
3MP0003635_abnormal_synaptic_transmissio3.99307304
4MP0004270_analgesia3.60541196
5MP0002063_abnormal_learning/memory/cond3.07636984
6MP0005409_darkened_coat_color2.94023969
7MP0003303_peritoneal_inflammation2.82695937
8MP0009745_abnormal_behavioral_response2.78857049
9MP0009780_abnormal_chondrocyte_physiolo2.63610338
10MP0002064_seizures2.54360735
11MP0009046_muscle_twitch2.39369852
12MP0000778_abnormal_nervous_system2.34035474
13MP0005423_abnormal_somatic_nervous2.32161610
14MP0001968_abnormal_touch/_nociception2.27739168
15MP0003172_abnormal_lysosome_physiology2.27078888
16MP0002572_abnormal_emotion/affect_behav2.25927159
17MP0005058_abnormal_lysosome_morphology2.21129615
18MP0002734_abnormal_mechanical_nocicepti2.18707230
19MP0005451_abnormal_body_composition2.14945123
20MP0003329_amyloid_beta_deposits2.12918954
21MP0002909_abnormal_adrenal_gland2.08080764
22MP0004858_abnormal_nervous_system2.07919126
23MP0004811_abnormal_neuron_physiology2.06083402
24MP0003191_abnormal_cellular_cholesterol2.05653312
25MP0001486_abnormal_startle_reflex2.01043915
26MP0008569_lethality_at_weaning1.94856526
27MP0008260_abnormal_autophagy1.94629902
28MP0002184_abnormal_innervation1.86884523
29MP0002733_abnormal_thermal_nociception1.84302947
30MP0002272_abnormal_nervous_system1.81092182
31MP0003690_abnormal_glial_cell1.78464479
32MP0002822_catalepsy1.75518734
33MP0003183_abnormal_peptide_metabolism1.71770635
34MP0004885_abnormal_endolymph1.66852412
35MP0000955_abnormal_spinal_cord1.64726817
36MP0001849_ear_inflammation1.60979244
37MP0002557_abnormal_social/conspecific_i1.59401322
38MP0002067_abnormal_sensory_capabilities1.56293236
39MP0001970_abnormal_pain_threshold1.55082284
40MP0002735_abnormal_chemical_nociception1.55054181
41MP0000569_abnormal_digit_pigmentation1.54477716
42MP0004130_abnormal_muscle_cell1.52766722
43MP0004924_abnormal_behavior1.49562305
44MP0005386_behavior/neurological_phenoty1.49562305
45MP0002736_abnormal_nociception_after1.44906080
46MP0002882_abnormal_neuron_morphology1.43819036
47MP0001440_abnormal_grooming_behavior1.41569613
48MP0008961_abnormal_basal_metabolism1.40228249
49MP0005076_abnormal_cell_differentiation1.39846458
50MP0001501_abnormal_sleep_pattern1.39216337
51MP0003566_abnormal_cell_adhesion1.38562999
52MP0002796_impaired_skin_barrier1.37429606
53MP0000920_abnormal_myelination1.36168103
54MP0003436_decreased_susceptibility_to1.35859819
55MP0005187_abnormal_penis_morphology1.34135161
56MP0002152_abnormal_brain_morphology1.32162223
57MP0003279_aneurysm1.31847664
58MP0002009_preneoplasia1.29444856
59MP0003787_abnormal_imprinting1.28918884
60MP0002066_abnormal_motor_capabilities/c1.28338485
61MP0003646_muscle_fatigue1.26223946
62MP0003879_abnormal_hair_cell1.25496199
63MP0004264_abnormal_extraembryonic_tissu1.25355919
64MP0005666_abnormal_adipose_tissue1.21529616
65MP0001958_emphysema1.19403612
66MP0005464_abnormal_platelet_physiology1.19282413
67MP0010234_abnormal_vibrissa_follicle1.17895278
68MP0000751_myopathy1.17672704
69MP0003091_abnormal_cell_migration1.17160896
70MP0003283_abnormal_digestive_organ1.17046075
71MP0003075_altered_response_to1.16665399
72MP0003633_abnormal_nervous_system1.16147524
73MP0005623_abnormal_meninges_morphology1.13180562
74MP0003938_abnormal_ear_development1.10946113
75MP0006276_abnormal_autonomic_nervous1.10710876
76MP0003300_gastrointestinal_ulcer1.09791970
77MP0008438_abnormal_cutaneous_collagen1.07229476
78MP0004947_skin_inflammation1.06509501
79MP0001299_abnormal_eye_distance/1.05322507
80MP0000537_abnormal_urethra_morphology1.05290562
81MP0004233_abnormal_muscle_weight1.05289769
82MP0003705_abnormal_hypodermis_morpholog1.03880171
83MP0000013_abnormal_adipose_tissue1.01968109
84MP0003122_maternal_imprinting1.01740170
85MP0000678_abnormal_parathyroid_gland1.01397084
86MP0003861_abnormal_nervous_system0.98596805
87MP0004510_myositis0.98158657
88MP0000681_abnormal_thyroid_gland0.97659754
89MP0001177_atelectasis0.96242280
90MP0002089_abnormal_postnatal_growth/wei0.95238920
91MP0003631_nervous_system_phenotype0.94022511
92MP0002069_abnormal_eating/drinking_beha0.91086729
93MP0001348_abnormal_lacrimal_gland0.89041012
94MP0000604_amyloidosis0.88586312
95MP0001502_abnormal_circadian_rhythm0.87855405
96MP0003763_abnormal_thymus_physiology0.85940031
97MP0003045_fibrosis0.84711765
98MP0002249_abnormal_larynx_morphology0.83452546
99MP0000631_abnormal_neuroendocrine_gland0.83441828
100MP0001984_abnormal_olfaction0.82986679
101MP0003634_abnormal_glial_cell0.82607768
102MP0005248_abnormal_Harderian_gland0.82246277
103MP0009840_abnormal_foam_cell0.81972377
104MP0004085_abnormal_heartbeat0.81508731
105MP0004145_abnormal_muscle_electrophysio0.81408392
106MP0002896_abnormal_bone_mineralization0.80134892
107MP0003828_pulmonary_edema0.79377029
108MP0005375_adipose_tissue_phenotype0.78852226
109MP0003123_paternal_imprinting0.78722814
110MP0005501_abnormal_skin_physiology0.78348968
111MP0002234_abnormal_pharynx_morphology0.77774510
112MP0000462_abnormal_digestive_system0.77177915
113MP0003137_abnormal_impulse_conducting0.75016343
114MP0008874_decreased_physiological_sensi0.74654852
115MP0000767_abnormal_smooth_muscle0.73563117
116MP0000534_abnormal_ureter_morphology0.73473195
117MP0009379_abnormal_foot_pigmentation0.72427527
118MP0005499_abnormal_olfactory_system0.72015199
119MP0005394_taste/olfaction_phenotype0.72015199
120MP0002133_abnormal_respiratory_system0.71458539
121MP0005388_respiratory_system_phenotype0.71458539
122MP0001188_hyperpigmentation0.71116321
123MP0001765_abnormal_ion_homeostasis0.70864325
124MP0003119_abnormal_digestive_system0.67602883
125MP0004215_abnormal_myocardial_fiber0.67112513
126MP0002081_perinatal_lethality0.66631539
127MP0002229_neurodegeneration0.66556142
128MP0002396_abnormal_hematopoietic_system0.65830496
129MP0003115_abnormal_respiratory_system0.65756824
130MP0002837_dystrophic_cardiac_calcinosis0.65693404
131MP0004185_abnormal_adipocyte_glucose0.65503180
132MP0001851_eye_inflammation0.65364879
133MP0002090_abnormal_vision0.63480768
134MP0001943_abnormal_respiration0.62661556
135MP0005535_abnormal_body_temperature0.62287621
136MP0000003_abnormal_adipose_tissue0.61988800
137MP0009278_abnormal_bone_marrow0.60989783
138MP0002752_abnormal_somatic_nervous0.60676355
139MP0002877_abnormal_melanocyte_morpholog0.60095334
140MP0003632_abnormal_nervous_system0.60026227
141MP0001270_distended_abdomen0.57583765
142MP0000747_muscle_weakness0.57424784

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.37027378
2Focal motor seizures (HP:0011153)4.54452957
3Visual hallucinations (HP:0002367)4.45422161
4Focal seizures (HP:0007359)4.10345338
5Action tremor (HP:0002345)3.48918535
6Ankle clonus (HP:0011448)3.32015272
7Papilledema (HP:0001085)3.24761701
8Supranuclear gaze palsy (HP:0000605)3.18193254
9Depression (HP:0000716)3.17442894
10Neurofibrillary tangles (HP:0002185)3.13436065
11Progressive cerebellar ataxia (HP:0002073)3.11624184
12Epileptic encephalopathy (HP:0200134)3.09401241
13Megalencephaly (HP:0001355)2.97329861
14Abnormality of the lower motor neuron (HP:0002366)2.94526759
15Genetic anticipation (HP:0003743)2.89922970
16Impaired vibration sensation in the lower limbs (HP:0002166)2.89120983
17Truncal ataxia (HP:0002078)2.88193502
18Insomnia (HP:0100785)2.83672791
19Mutism (HP:0002300)2.82191112
20Absence seizures (HP:0002121)2.80548775
21Agitation (HP:0000713)2.74992177
22Thin bony cortex (HP:0002753)2.74155826
23Poor eye contact (HP:0000817)2.74029614
24Atonic seizures (HP:0010819)2.71476321
25Impaired smooth pursuit (HP:0007772)2.67929264
26Hyperacusis (HP:0010780)2.67905714
27Dysmetric saccades (HP:0000641)2.65989558
28Stereotypic behavior (HP:0000733)2.63399914
29Impaired social interactions (HP:0000735)2.63286915
30Abnormal social behavior (HP:0012433)2.63286915
31Pointed chin (HP:0000307)2.61885981
32Urinary urgency (HP:0000012)2.61557130
33Amyotrophic lateral sclerosis (HP:0007354)2.60228364
34Broad-based gait (HP:0002136)2.58608899
35Termporal pattern (HP:0011008)2.57518930
36Insidious onset (HP:0003587)2.57518930
37Upper limb amyotrophy (HP:0009129)2.55064463
38Distal upper limb amyotrophy (HP:0007149)2.55064463
39Generalized tonic-clonic seizures (HP:0002069)2.54821731
40Hemiplegia (HP:0002301)2.54605471
41Rectal prolapse (HP:0002035)2.50206932
42Drooling (HP:0002307)2.49698702
43Excessive salivation (HP:0003781)2.49698702
44Dysdiadochokinesis (HP:0002075)2.47598557
45Abnormality of ocular smooth pursuit (HP:0000617)2.45673730
46Annular pancreas (HP:0001734)2.43999835
47Anxiety (HP:0000739)2.41654128
48Urinary bladder sphincter dysfunction (HP:0002839)2.41457853
49Ankyloglossia (HP:0010296)2.40680008
50Obstructive sleep apnea (HP:0002870)2.38783839
51Dysmetria (HP:0001310)2.36804626
52Dialeptic seizures (HP:0011146)2.36397250
53Apathy (HP:0000741)2.35833926
54Hand muscle atrophy (HP:0009130)2.35152826
55Elfin facies (HP:0004428)2.33485176
56Diminished motivation (HP:0000745)2.33074141
57Gaze-evoked nystagmus (HP:0000640)2.32982452
58Protrusio acetabuli (HP:0003179)2.32003451
59Macroorchidism (HP:0000053)2.31960739
60Shallow orbits (HP:0000586)2.31959553
61Febrile seizures (HP:0002373)2.30178774
62Growth hormone excess (HP:0000845)2.29878472
63Neoplasm of the heart (HP:0100544)2.27628273
64Amblyopia (HP:0000646)2.26883225
65Torticollis (HP:0000473)2.25686529
66Abnormality of binocular vision (HP:0011514)2.23488716
67Diplopia (HP:0000651)2.23488716
68Cerebral inclusion bodies (HP:0100314)2.21854619
69Increased variability in muscle fiber diameter (HP:0003557)2.19745630
70Abnormal eating behavior (HP:0100738)2.18495365
71Eczematoid dermatitis (HP:0000976)2.15623214
72Hyperparathyroidism (HP:0000843)2.13833770
73Dysostosis multiplex (HP:0000943)2.13443169
74Focal dystonia (HP:0004373)2.12704301
75Inappropriate behavior (HP:0000719)2.12514780
76Spastic gait (HP:0002064)2.11842921
77Akinesia (HP:0002304)2.09711475
78Slow saccadic eye movements (HP:0000514)2.09022100
79Stridor (HP:0010307)2.07862496
80Scanning speech (HP:0002168)2.07209443
81Postural tremor (HP:0002174)2.05871721
82Overgrowth (HP:0001548)2.05431403
83Abnormality of oral frenula (HP:0000190)2.03827757
84Sacral dimple (HP:0000960)2.01173403
85Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.01157529
86Ventricular fibrillation (HP:0001663)1.99944520
87Distal lower limb amyotrophy (HP:0008944)1.99704269
88Overriding aorta (HP:0002623)1.98084630
89Spinal canal stenosis (HP:0003416)1.98067171
90Germ cell neoplasia (HP:0100728)1.97592938
91Renal duplication (HP:0000075)1.97164633
92Mucopolysacchariduria (HP:0008155)1.96858828
93Urinary glycosaminoglycan excretion (HP:0003541)1.96858828
94Hypoventilation (HP:0002791)1.95737132
95Asymmetry of the thorax (HP:0001555)1.95641558
96Limb dystonia (HP:0002451)1.95470075
97Aqueductal stenosis (HP:0002410)1.95156877
98Flat acetabular roof (HP:0003180)1.94735047
99Epileptiform EEG discharges (HP:0011182)1.94529911
100Hypercortisolism (HP:0001578)1.94179499
101EEG with generalized epileptiform discharges (HP:0011198)1.91751708
102Deep palmar crease (HP:0006191)1.91440778
103Lower limb asymmetry (HP:0100559)1.91332553
104Neuronal loss in central nervous system (HP:0002529)1.91196607
105Hemiparesis (HP:0001269)1.91072859
106Sporadic (HP:0003745)1.91060530
107Achilles tendon contracture (HP:0001771)1.91056213
108Testicular neoplasm (HP:0010788)1.90874992
109Intention tremor (HP:0002080)1.90847786
110Hypsarrhythmia (HP:0002521)1.90029218
111Abnormality of polysaccharide metabolism (HP:0011012)1.89706001
112Abnormality of glycosaminoglycan metabolism (HP:0004371)1.89706001
113Abnormality of mucopolysaccharide metabolism (HP:0011020)1.89706001
114Abnormality of the corticospinal tract (HP:0002492)1.88747009
115Renovascular hypertension (HP:0100817)1.88701795
116Centrally nucleated skeletal muscle fibers (HP:0003687)1.88606026
117Hammertoe (HP:0001765)1.88582036
118Broad face (HP:0000283)1.88366382
119Peripheral hypomyelination (HP:0007182)1.88183213
120Postural instability (HP:0002172)1.86943931
121Hyperventilation (HP:0002883)1.85595127
122Decreased motor nerve conduction velocity (HP:0003431)1.84363865
123Lower limb amyotrophy (HP:0007210)1.84285758
124Impaired vibratory sensation (HP:0002495)1.84269331
125Abnormality of skeletal muscle fiber size (HP:0012084)1.83908442
126Premature rupture of membranes (HP:0001788)1.83836315
127Craniofacial dystonia (HP:0012179)1.82549921
128Lower limb muscle weakness (HP:0007340)1.82423676
129Cerebral aneurysm (HP:0004944)1.81244541
130Obsessive-compulsive behavior (HP:0000722)1.81216519
131Rapidly progressive (HP:0003678)1.80573785
132Distal sensory impairment (HP:0002936)1.80020093
133Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.79441749
134Aneurysm (HP:0002617)1.79419026
135Vertebral compression fractures (HP:0002953)1.78802065
136Foot dorsiflexor weakness (HP:0009027)1.76044265
137Back pain (HP:0003418)1.75623351
138Disproportionate tall stature (HP:0001519)1.75329638
139Rigidity (HP:0002063)1.74862977
140Mitral regurgitation (HP:0001653)1.74756381
141Sparse lateral eyebrow (HP:0005338)1.67656177
142Increased connective tissue (HP:0009025)1.66847607
143Cellulitis (HP:0100658)1.65037671
144Onion bulb formation (HP:0003383)1.63354923
145Arterial tortuosity (HP:0005116)1.63328853
146Hyperthyroidism (HP:0000836)1.62850293
147Vascular tortuosity (HP:0004948)1.60551232
148Genu recurvatum (HP:0002816)1.60294481
149Dilatation of the ascending aorta (HP:0005111)1.59526077
150Abnormality of saccadic eye movements (HP:0000570)1.59506171
151Precocious puberty (HP:0000826)1.57998497
152Tetraplegia (HP:0002445)1.57873019
153Abnormal gallbladder physiology (HP:0012438)1.57802687
154Cholecystitis (HP:0001082)1.57802687
155Abnormal cortical bone morphology (HP:0003103)1.57685195
156Increased IgE level (HP:0003212)1.57378329

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.09134617
2NTRK33.45512986
3MAP3K93.42907481
4MINK13.07020394
5EPHA42.84991701
6MAP3K42.37547891
7PAK62.27630299
8DAPK22.27352986
9TRIB32.22571140
10CAMKK12.21189503
11PKN22.16890320
12KSR22.12522594
13ERN12.09331586
14RIPK41.99623177
15NTRK21.96023295
16KSR11.92034962
17MAP3K121.89218379
18SMG11.83059723
19SIK11.82663846
20TESK11.81524001
21SCYL21.72433566
22PRKD31.68621582
23MAP2K71.65488853
24MAP2K41.64973848
25PHKG21.61609454
26PHKG11.61609454
27PRPF4B1.59388862
28SIK21.49197607
29EPHB11.48629366
30RET1.46182061
31MAP3K21.44648561
32LATS21.42476881
33TYRO31.41740576
34DAPK11.40713423
35CDK51.40592359
36TNK21.37267955
37PRKD21.36184430
38MAP2K31.32146923
39NTRK11.31226564
40RIPK11.28906748
41STK111.28330534
42MAP3K111.27682177
43FES1.24673125
44ALK1.24629516
45CAMKK21.22219167
46LMTK21.17100550
47CDK191.16689772
48RPS6KA21.16385542
49TAOK21.15743152
50MAP3K131.14639306
51UHMK11.10706050
52DMPK1.06477028
53CDK121.05659846
54STK381.04771565
55TAOK11.03962297
56MAP3K61.03688807
57FGFR41.01558819
58EEF2K1.00619240
59LIMK10.98355554
60MAPK120.98026752
61CDK140.95450388
62ZAP700.94303762
63PRKCH0.92770740
64CDK150.89011452
65CDK180.87871849
66PDGFRA0.87615718
67CSNK1G20.87321017
68MAPK130.87133859
69PAK30.83546108
70PTK60.83344688
71PLK20.83141699
72MAP3K30.82309234
73MARK20.81170399
74TESK20.80537239
75CAMK1G0.79888875
76PRKCG0.79567181
77CDK11A0.78627927
78ERBB30.76883540
79DAPK30.74704284
80FER0.72907236
81RAF10.69270702
82SIK30.68660246
83NEK10.68144632
84FGFR20.67662391
85CAMK10.67545939
86GRK60.66819467
87MTOR0.66156411
88FGFR10.65066835
89SGK4940.64317435
90FYN0.64237698
91DYRK1B0.63907170
92PRKCZ0.61638401
93ICK0.59564595
94PTK2B0.59509268
95DYRK1A0.58368423
96MAP3K70.58357999
97JAK20.57921740
98GRK50.57471336
99ROCK10.55084612
100TRPM70.53933099
101PRKG20.53479140
102IRAK20.53444754
103HIPK20.53049851
104HCK0.51992331
105PTK20.50894364
106PDK10.48275117
107TTN0.47917090
108TNIK0.47843696
109RPS6KL10.47762505
110RPS6KC10.47762505
111PDGFRB0.46736429
112ILK0.46270345
113PRKD10.46239385
114ROCK20.45795963
115CAMK2A0.45526703
116CDC42BPA0.44562828
117SGK30.44151715
118WNK10.43955068
119MAP3K10.43812094
120RPS6KA30.43621967
121ARAF0.41687300
122MAPK100.41546382
123CAMK40.41531241
124PDPK10.41001616
125MAP2K60.40181255
126EPHB20.38871836
127PAK20.38798093
128CAMK1D0.36853627
129CAMK2B0.32925833
130BMX0.32785775
131SGK10.32412526
132ERBB20.32282286
133SGK2230.31962874

Predicted pathways (KEGG)

RankGene SetZ-score
1Long-term potentiation_Homo sapiens_hsa047202.47602597
2Synaptic vesicle cycle_Homo sapiens_hsa047212.46799895
3Nicotine addiction_Homo sapiens_hsa050332.42616031
4Circadian entrainment_Homo sapiens_hsa047132.34986269
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.33231884
6Olfactory transduction_Homo sapiens_hsa047402.24542502
7GABAergic synapse_Homo sapiens_hsa047272.18967989
8Glutamatergic synapse_Homo sapiens_hsa047242.14931784
9Dopaminergic synapse_Homo sapiens_hsa047282.09914897
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.09215759
11Morphine addiction_Homo sapiens_hsa050321.98508115
12Amphetamine addiction_Homo sapiens_hsa050311.92262439
13Cholinergic synapse_Homo sapiens_hsa047251.91011712
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.81742845
15Aldosterone synthesis and secretion_Homo sapiens_hsa049251.73920587
16Salivary secretion_Homo sapiens_hsa049701.71842145
17Gastric acid secretion_Homo sapiens_hsa049711.70358533
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.70320428
19Insulin secretion_Homo sapiens_hsa049111.66626351
20Long-term depression_Homo sapiens_hsa047301.65073864
21Oxytocin signaling pathway_Homo sapiens_hsa049211.58282405
22Acute myeloid leukemia_Homo sapiens_hsa052211.56963638
23Glioma_Homo sapiens_hsa052141.56207025
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.53948077
25GnRH signaling pathway_Homo sapiens_hsa049121.52912606
26Renin secretion_Homo sapiens_hsa049241.52533911
27Nitrogen metabolism_Homo sapiens_hsa009101.48452437
28Cocaine addiction_Homo sapiens_hsa050301.47651637
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.46924241
30Gap junction_Homo sapiens_hsa045401.46378375
31Estrogen signaling pathway_Homo sapiens_hsa049151.38774322
32Other glycan degradation_Homo sapiens_hsa005111.37453175
33Axon guidance_Homo sapiens_hsa043601.35420013
34Type II diabetes mellitus_Homo sapiens_hsa049301.25132444
35Serotonergic synapse_Homo sapiens_hsa047261.24197478
36ErbB signaling pathway_Homo sapiens_hsa040121.21842172
37Endometrial cancer_Homo sapiens_hsa052131.18544286
38Dorso-ventral axis formation_Homo sapiens_hsa043201.17384915
39Melanogenesis_Homo sapiens_hsa049161.16788518
40VEGF signaling pathway_Homo sapiens_hsa043701.16246945
41Neurotrophin signaling pathway_Homo sapiens_hsa047221.11545223
42cAMP signaling pathway_Homo sapiens_hsa040241.11344917
43Calcium signaling pathway_Homo sapiens_hsa040201.11178997
44Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.11040483
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.10672951
46Taste transduction_Homo sapiens_hsa047421.10444916
47mTOR signaling pathway_Homo sapiens_hsa041501.09906996
48B cell receptor signaling pathway_Homo sapiens_hsa046621.07769881
49Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05019654
50Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.04131825
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03085629
52Non-small cell lung cancer_Homo sapiens_hsa052231.02387474
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99528559
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98822761
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.96991317
56Oocyte meiosis_Homo sapiens_hsa041140.95946859
57Glycosaminoglycan degradation_Homo sapiens_hsa005310.95859817
58Notch signaling pathway_Homo sapiens_hsa043300.94651425
59Renal cell carcinoma_Homo sapiens_hsa052110.93648958
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.92667218
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90844721
62Colorectal cancer_Homo sapiens_hsa052100.89040187
63Insulin signaling pathway_Homo sapiens_hsa049100.86909606
64Chronic myeloid leukemia_Homo sapiens_hsa052200.85744989
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.83521216
66Central carbon metabolism in cancer_Homo sapiens_hsa052300.82216486
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.81151959
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.80414873
69Dilated cardiomyopathy_Homo sapiens_hsa054140.79345123
70Choline metabolism in cancer_Homo sapiens_hsa052310.79325934
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77921084
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77572598
73Rap1 signaling pathway_Homo sapiens_hsa040150.77464822
74Longevity regulating pathway - mammal_Homo sapiens_hsa042110.77091430
75Amoebiasis_Homo sapiens_hsa051460.76878816
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76221029
77Thyroid hormone synthesis_Homo sapiens_hsa049180.75478658
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.74972685
79MAPK signaling pathway_Homo sapiens_hsa040100.74443759
80Glucagon signaling pathway_Homo sapiens_hsa049220.73975033
81Vascular smooth muscle contraction_Homo sapiens_hsa042700.73630259
82Pancreatic secretion_Homo sapiens_hsa049720.72980411
83Osteoclast differentiation_Homo sapiens_hsa043800.72762738
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.72519739
85* Endocytosis_Homo sapiens_hsa041440.69000869
86Wnt signaling pathway_Homo sapiens_hsa043100.68785137
87Alcoholism_Homo sapiens_hsa050340.67591372
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.66665870
89Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65721907
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.65354911
91Ras signaling pathway_Homo sapiens_hsa040140.64812631
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63386901
93Thyroid cancer_Homo sapiens_hsa052160.60712613
94Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60084510
95Cardiac muscle contraction_Homo sapiens_hsa042600.57928342
96AMPK signaling pathway_Homo sapiens_hsa041520.57772644
97Pancreatic cancer_Homo sapiens_hsa052120.57376503
98Proteoglycans in cancer_Homo sapiens_hsa052050.57242124
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56235696
100Phototransduction_Homo sapiens_hsa047440.55338436
101Hepatitis C_Homo sapiens_hsa051600.54213579
102Platelet activation_Homo sapiens_hsa046110.53791068
103Insulin resistance_Homo sapiens_hsa049310.53125474
104Pentose phosphate pathway_Homo sapiens_hsa000300.52968460
105Prostate cancer_Homo sapiens_hsa052150.52388030
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52326145
107Prolactin signaling pathway_Homo sapiens_hsa049170.51420678
108Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.49648071
109HIF-1 signaling pathway_Homo sapiens_hsa040660.49621072
110T cell receptor signaling pathway_Homo sapiens_hsa046600.48555352
111Prion diseases_Homo sapiens_hsa050200.48425024
112Chemokine signaling pathway_Homo sapiens_hsa040620.48146870
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.47878356
114Vibrio cholerae infection_Homo sapiens_hsa051100.46672635
115Focal adhesion_Homo sapiens_hsa045100.46287718
116Hippo signaling pathway_Homo sapiens_hsa043900.45767455
117Bile secretion_Homo sapiens_hsa049760.45536489
118Inositol phosphate metabolism_Homo sapiens_hsa005620.44908958
119Hedgehog signaling pathway_Homo sapiens_hsa043400.44508929

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