VPS37B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)8.67096152
2interferon-gamma production (GO:0032609)7.75222335
3response to muramyl dipeptide (GO:0032495)7.20336638
4negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)7.16972252
5embryonic process involved in female pregnancy (GO:0060136)6.72567504
6response to interleukin-15 (GO:0070672)6.55510685
7regulation of gamma-delta T cell differentiation (GO:0045586)6.48134682
8negative regulation of cell killing (GO:0031342)6.43183905
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.43183905
10cellular response to interleukin-15 (GO:0071350)6.33799934
11negative regulation of bone resorption (GO:0045779)6.13033011
12positive regulation of gamma-delta T cell activation (GO:0046645)5.85409688
13regulation of gamma-delta T cell activation (GO:0046643)5.84220977
14regulation of chronic inflammatory response (GO:0002676)5.74939083
15negative regulation of interleukin-1 beta production (GO:0032691)5.53105850
16negative T cell selection (GO:0043383)5.49869248
17positive thymic T cell selection (GO:0045059)5.45496105
18positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.40774501
19NIK/NF-kappaB signaling (GO:0038061)5.31172977
20positive T cell selection (GO:0043368)5.19292772
21negative thymic T cell selection (GO:0045060)5.19006470
22endothelial cell chemotaxis (GO:0035767)4.96016127
23negative regulation of bone remodeling (GO:0046851)4.94409955
24thymic T cell selection (GO:0045061)4.86692833
25protein K11-linked deubiquitination (GO:0035871)4.83899067
26T cell selection (GO:0045058)4.77089762
27regulation of germinal center formation (GO:0002634)4.75238718
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.70029619
29regulation of interleukin-12 biosynthetic process (GO:0045075)4.48893851
30regulation of isotype switching to IgG isotypes (GO:0048302)4.45143776
31T-helper cell differentiation (GO:0042093)4.39978995
32CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)4.39978995
33negative regulation of interleukin-1 production (GO:0032692)4.39528557
34negative regulation of innate immune response (GO:0045824)4.20556680
35negative regulation of tissue remodeling (GO:0034104)4.14090195
36alpha-beta T cell differentiation (GO:0046632)4.13931392
37regulation of toll-like receptor 4 signaling pathway (GO:0034143)4.02480883
38alpha-beta T cell activation (GO:0046631)4.00876668
39T cell receptor signaling pathway (GO:0050852)3.99917451
40T cell differentiation involved in immune response (GO:0002292)3.93328564
41alpha-beta T cell differentiation involved in immune response (GO:0002293)3.93328564
42alpha-beta T cell activation involved in immune response (GO:0002287)3.93328564
43antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.92472824
44antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.92472824
45modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.91102828
46positive regulation by organism of defense response of other organism involved in symbiotic interact3.91102828
47modulation by symbiont of host immune response (GO:0052553)3.91102828
48positive regulation by symbiont of host defense response (GO:0052509)3.91102828
49modulation by symbiont of host defense response (GO:0052031)3.91102828
50modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.91102828
51T cell migration (GO:0072678)3.84373522
52nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423)3.81242303
53positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.81227659
54neutrophil activation involved in immune response (GO:0002283)3.80457633
55trophectodermal cell differentiation (GO:0001829)3.75971155
56JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.73793423
57regulation of B cell receptor signaling pathway (GO:0050855)3.73498120
58regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.73227527
59response to peptidoglycan (GO:0032494)3.69334755
60regulation of response to interferon-gamma (GO:0060330)3.63625292
61B cell homeostasis (GO:0001782)3.63535694
62positive regulation of heat generation (GO:0031652)3.62524836
63regulation of fever generation (GO:0031620)3.62323805
64positive regulation of interleukin-2 production (GO:0032743)3.61617995
65regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.61053485
66mature B cell differentiation involved in immune response (GO:0002313)3.59849064
67regulation of T cell tolerance induction (GO:0002664)3.58695761
68regulation of interleukin-2 biosynthetic process (GO:0045076)3.56065602
69leukocyte aggregation (GO:0070486)3.51295804
70T cell differentiation (GO:0030217)3.50577961
71negative regulation of erythrocyte differentiation (GO:0045647)3.50498733
72regulation of interleukin-2 production (GO:0032663)3.43934293
73regulation of defense response to virus by host (GO:0050691)3.42985199
74detection of other organism (GO:0098543)3.41997327
75detection of bacterium (GO:0016045)3.40438890
76positive regulation of isotype switching (GO:0045830)3.39862015
77osteoclast differentiation (GO:0030316)3.38092420
78cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)3.36405760
79antigen processing and presentation of endogenous antigen (GO:0019883)3.33889461
80negative regulation of interleukin-2 production (GO:0032703)3.31740748
81T cell costimulation (GO:0031295)3.30412390
82antigen receptor-mediated signaling pathway (GO:0050851)3.29702277
83mature B cell differentiation (GO:0002335)3.29119359
84neutrophil activation (GO:0042119)3.27931353
85lymphocyte costimulation (GO:0031294)3.22459894
86regulation of bone resorption (GO:0045124)3.21934005
87negative regulation of interleukin-6 production (GO:0032715)3.20535063
88negative regulation of toll-like receptor signaling pathway (GO:0034122)3.19962004
89regulation of mast cell degranulation (GO:0043304)3.19642553
90germinal center formation (GO:0002467)3.18457256
91tumor necrosis factor-mediated signaling pathway (GO:0033209)3.16416234
92positive regulation of tolerance induction (GO:0002645)3.15902291
93entrainment of circadian clock by photoperiod (GO:0043153)3.15516555
94regulation of leukocyte degranulation (GO:0043300)3.14399623
95negative regulation of inclusion body assembly (GO:0090084)3.13949284
96lymphocyte homeostasis (GO:0002260)3.13141064
97granulocyte activation (GO:0036230)3.11644936
98decidualization (GO:0046697)3.10269344
99endoderm formation (GO:0001706)3.08218133
100macrophage activation involved in immune response (GO:0002281)3.06848803
101positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.05335919
102immunoglobulin mediated immune response (GO:0016064)3.03633028
103regulation of memory T cell differentiation (GO:0043380)3.03287187
104negative regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043124)3.02328308
105mucosal-associated lymphoid tissue development (GO:0048537)2.99790477
106Peyers patch development (GO:0048541)2.99790477
107regulation of thymocyte apoptotic process (GO:0070243)2.98739373
108natural killer cell activation (GO:0030101)2.98427162
109positive regulation of prostaglandin secretion (GO:0032308)2.98259877
110regulation of myeloid leukocyte mediated immunity (GO:0002886)2.96910944
111CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.96779634
112response to laminar fluid shear stress (GO:0034616)2.91880228
113regulation of mast cell activation involved in immune response (GO:0033006)2.88677754
114regulation of interferon-beta biosynthetic process (GO:0045357)2.88344181
115negative regulation of interleukin-8 production (GO:0032717)2.87032378
116positive regulation of histone deacetylation (GO:0031065)2.86457695
117leukocyte cell-cell adhesion (GO:0007159)2.86088081
118regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.85876864
119response to corticosterone (GO:0051412)2.84848814
120T cell activation involved in immune response (GO:0002286)2.84676076
121positive regulation of DNA recombination (GO:0045911)2.83625611
122protein K48-linked deubiquitination (GO:0071108)2.83444180
123myeloid dendritic cell activation (GO:0001773)2.82735097
124negative regulation of glycoprotein biosynthetic process (GO:0010561)2.80685464
125negative regulation of interleukin-12 production (GO:0032695)2.70116839
126response to host (GO:0075136)2.68694787
127response to host defenses (GO:0052200)2.68694787
128response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.68694787
129response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.68315395
130response to host immune response (GO:0052572)2.68315395
131detection of external biotic stimulus (GO:0098581)2.67802963
132positive regulation of T cell mediated cytotoxicity (GO:0001916)2.66321269
133lipopolysaccharide-mediated signaling pathway (GO:0031663)2.65054951
134cellular extravasation (GO:0045123)2.63856701
135negative regulation of stress fiber assembly (GO:0051497)2.63525608
136positive regulation of protein deacetylation (GO:0090312)2.61795520
137modulation by virus of host process (GO:0019054)2.60131159
138negative regulation of leukocyte mediated immunity (GO:0002704)2.55775975
139regulation of defense response to virus by virus (GO:0050690)2.52288661
140megakaryocyte development (GO:0035855)2.52107487
141regulation of regulated secretory pathway (GO:1903305)2.50950673
142regulation of T cell mediated cytotoxicity (GO:0001914)2.48994334
143regulation of natural killer cell mediated immunity (GO:0002715)2.47581521
144regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.47581521
145positive regulation of Cdc42 GTPase activity (GO:0043089)2.47579454
146regulation of necroptotic process (GO:0060544)2.44543590
147response to protozoan (GO:0001562)2.44247425
148myeloid cell activation involved in immune response (GO:0002275)2.44047127
149positive regulation of B cell differentiation (GO:0045579)2.43885514
150negative regulation of lymphocyte mediated immunity (GO:0002707)2.42371637
151mannose metabolic process (GO:0006013)2.41156036
1523-UTR-mediated mRNA stabilization (GO:0070935)2.41090631
153modulation by symbiont of host cellular process (GO:0044068)2.40824965
154defense response to protozoan (GO:0042832)2.39687396
155protein localization to endosome (GO:0036010)2.39685555
156response to type I interferon (GO:0034340)2.39544295
157regulation of mast cell activation (GO:0033003)2.38400884
158leukocyte migration involved in inflammatory response (GO:0002523)2.38027731
159regulation of T-helper 2 cell differentiation (GO:0045628)2.36065344
160type I interferon signaling pathway (GO:0060337)2.34341746
161cellular response to type I interferon (GO:0071357)2.34341746
162signal complex assembly (GO:0007172)2.34053886
163positive regulation of granulocyte differentiation (GO:0030854)2.33353564
164detection of biotic stimulus (GO:0009595)2.32215628
165stress fiber assembly (GO:0043149)2.31672811
166thrombin receptor signaling pathway (GO:0070493)2.30707733
167leukocyte degranulation (GO:0043299)2.29912361
168hypotonic response (GO:0006971)2.28824633
169barbed-end actin filament capping (GO:0051016)2.28449223
170negative regulation of myotube differentiation (GO:0010832)2.28338200
171regulation of tumor necrosis factor superfamily cytokine production (GO:1903555)2.28202547
172positive regulation of mast cell activation (GO:0033005)2.28085740
173negative regulation of tumor necrosis factor production (GO:0032720)2.26815686
174tolerance induction (GO:0002507)10.2918181

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.02215814
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.63102574
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.82374034
4* MYC_22102868_ChIP-Seq_BL_Human3.93689895
5* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.63341459
6* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.59834859
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.49734689
8RUNX_20019798_ChIP-Seq_JUKART_Human3.44376372
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.90818814
10STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.82201070
11TCF7_22412390_ChIP-Seq_EML_Mouse2.80476492
12* MYB_26560356_Chip-Seq_TH2_Human2.79523564
13TP63_17297297_ChIP-ChIP_HaCaT_Human2.77631125
14MAF_26560356_Chip-Seq_TH1_Human2.69131607
15SCL_19346495_ChIP-Seq_HPC-7_Human2.68744759
16* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.65590542
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.53814034
18* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.52194932
19* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.52170410
20VDR_21846776_ChIP-Seq_THP-1_Human2.43197620
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.40668399
22* MYB_26560356_Chip-Seq_TH1_Human2.39747436
23KDM2B_26808549_Chip-Seq_DND41_Human2.30586904
24RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.30401926
25* UTX_26944678_Chip-Seq_JUKART_Human2.29428982
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.22838314
27IRF8_22096565_ChIP-ChIP_GC-B_Human2.21916215
28SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.05068301
29RARG_19884340_ChIP-ChIP_MEFs_Mouse1.99946689
30* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.96742463
31CLOCK_20551151_ChIP-Seq_293T_Human1.96708105
32* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.89136212
33MYB_21317192_ChIP-Seq_ERMYB_Mouse1.87646395
34NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.84831821
35* RUNX1_22412390_ChIP-Seq_EML_Mouse1.83809752
36* KDM2B_26808549_Chip-Seq_JURKAT_Human1.72952219
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.71039707
38* ELK3_25401928_ChIP-Seq_HUVEC_Human1.70902905
39TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.69992903
40* MAF_26560356_Chip-Seq_TH2_Human1.68953559
41* VDR_24763502_ChIP-Seq_THP-1_Human1.68842043
42BRD4_27068464_Chip-Seq_AML-cells_Mouse1.67059589
43RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.66944686
44IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.64847451
45NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61335019
46GATA3_27048872_Chip-Seq_THYMUS_Human1.59291537
47* IRF8_27001747_Chip-Seq_BMDM_Mouse1.57857390
48CTCF_27219007_Chip-Seq_ERYTHROID_Human1.48020803
49P68_20966046_ChIP-Seq_HELA_Human1.46671251
50BCL6_27268052_Chip-Seq_Bcells_Human1.45960564
51BCOR_27268052_Chip-Seq_Bcells_Human1.45708928
52ZNF263_19887448_ChIP-Seq_K562_Human1.45464257
53HIF1A_21447827_ChIP-Seq_MCF-7_Human1.43433372
54NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.39288739
55* SA1_27219007_Chip-Seq_ERYTHROID_Human1.38520623
56ELF1_20517297_ChIP-Seq_JURKAT_Human1.36217058
57GATA2_21666600_ChIP-Seq_HMVEC_Human1.36031198
58* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.35567443
59TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32790987
60GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.32721828
61RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.32105628
62KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32049805
63* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.26696919
64LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.26527292
65TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.24837488
66FOXO3_23340844_ChIP-Seq_DLD1_Human1.23381575
67STAT6_21828071_ChIP-Seq_BEAS2B_Human1.21059478
68TET1_21451524_ChIP-Seq_MESCs_Mouse1.20385049
69GATA1_19941826_ChIP-Seq_K562_Human1.19160438
70* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.19129461
71PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.18094482
72CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16101906
73* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14381701
74SMC4_20622854_ChIP-Seq_HELA_Human1.14376275
75NCOR1_26117541_ChIP-Seq_K562_Human1.14087043
76CREB1_26743006_Chip-Seq_LNCaP_Human1.13359309
77MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.11604796
78TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10867744
79P63_26484246_Chip-Seq_KERATINOCYTES_Human1.09987040
80LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08407996
81CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08133672
82KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.07968615
83KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.07968615
84KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.07968615
85PU.1_20513432_ChIP-Seq_Bcells_Mouse1.07697129
86SPI1_23547873_ChIP-Seq_NB4_Human1.07515135
87P300_27058665_Chip-Seq_ZR-75-30cells_Human1.06919494
88* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.06541988
89ATF3_27146783_Chip-Seq_COLON_Human1.06064371
90ESR2_21235772_ChIP-Seq_MCF-7_Human1.05498640
91SRY_22984422_ChIP-ChIP_TESTIS_Rat1.05420724
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05281038
93EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05102770
94PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03769695
95* VDR_24787735_ChIP-Seq_THP-1_Human1.03539318
96* TP63_22573176_ChIP-Seq_HFKS_Human1.03050241
97* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.02942628
98PHF8_20622854_ChIP-Seq_HELA_Human1.02647528
99TP53_22127205_ChIP-Seq_IMR90_Human1.01936516
100RUNX1_27514584_Chip-Seq_MCF-7_Human1.01394154
101E2F1_20622854_ChIP-Seq_HELA_Human1.01246054
102TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00925457
103* KDM2B_26808549_Chip-Seq_K562_Human1.00843167
104SPI1_23127762_ChIP-Seq_K562_Human1.00658568
105* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.99892411
106PU_27001747_Chip-Seq_BMDM_Mouse0.98206052
107PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97397305
108* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97116612
109FOXM1_23109430_ChIP-Seq_U2OS_Human0.96347303
110* RACK7_27058665_Chip-Seq_MCF-7_Human0.95302445
111SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94986825
112SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.93266519
113* GATA2_19941826_ChIP-Seq_K562_Human0.91851137
114LXR_22292898_ChIP-Seq_THP-1_Human0.90765255
115IRF8_21731497_ChIP-ChIP_J774_Mouse0.90669625
116THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.88918945
117* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87640610
118* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87415412
119* UBF1/2_26484160_Chip-Seq_HMECs_Human0.87338845
120GATA2_22383799_ChIP-Seq_G1ME_Mouse0.87230896
121FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.84920769
122* GATA1_19941827_ChIP-Seq_MEL_Mouse0.84690853
123ESR1_21235772_ChIP-Seq_MCF-7_Human0.82629284
124* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.82290144
125SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.81904026
126* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81730009
127PPAR_26484153_Chip-Seq_NCI-H1993_Human0.80757823
128GATA3_26560356_Chip-Seq_TH2_Human0.79888210
129NFIB_24661679_ChIP-Seq_LUNG_Mouse0.76432658
130RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.76093691
131CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.76093229
132BP1_19119308_ChIP-ChIP_Hs578T_Human0.75680486
133* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.75247362
134GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74292392

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.81099495
2MP0000685_abnormal_immune_system4.50928115
3MP0005671_abnormal_response_to3.49657138
4MP0004510_myositis3.22005876
5MP0005387_immune_system_phenotype3.14211671
6MP0001790_abnormal_immune_system3.14211671
7MP0004947_skin_inflammation3.10201730
8MP0001800_abnormal_humoral_immune3.07561251
9MP0005000_abnormal_immune_tolerance3.06805978
10MP0002723_abnormal_immune_serum2.72580047
11MP0002405_respiratory_system_inflammati2.71898966
12MP0002138_abnormal_hepatobiliary_system2.69995355
13MP0002933_joint_inflammation2.55910196
14MP0003724_increased_susceptibility_to2.54845540
15MP0003303_peritoneal_inflammation2.50518360
16MP0002420_abnormal_adaptive_immunity2.45393202
17MP0006082_CNS_inflammation2.42895597
18MP0001819_abnormal_immune_cell2.42424040
19MP0002452_abnormal_antigen_presenting2.42053766
20MP0010155_abnormal_intestine_physiology2.41814368
21MP0003436_decreased_susceptibility_to2.35715114
22MP0002398_abnormal_bone_marrow2.29530122
23MP0009333_abnormal_splenocyte_physiolog2.23041296
24MP0009785_altered_susceptibility_to2.18813425
25MP0000703_abnormal_thymus_morphology2.18401079
26MP0000716_abnormal_immune_system2.12923794
27MP0001873_stomach_inflammation2.10898697
28MP0003300_gastrointestinal_ulcer2.02866921
29MP0005451_abnormal_body_composition1.96031964
30MP0003191_abnormal_cellular_cholesterol1.94787960
31MP0002722_abnormal_immune_system1.89084679
32MP0008961_abnormal_basal_metabolism1.88607055
33MP0003866_abnormal_defecation1.84027017
34MP0001835_abnormal_antigen_presentation1.83763864
35MP0003828_pulmonary_edema1.81905681
36MP0002166_altered_tumor_susceptibility1.81463611
37MP0000689_abnormal_spleen_morphology1.81453228
38MP0001845_abnormal_inflammatory_respons1.80586080
39MP0003172_abnormal_lysosome_physiology1.79745633
40MP0005025_abnormal_response_to1.79544274
41MP0001851_eye_inflammation1.76613286
42MP0005058_abnormal_lysosome_morphology1.74659589
43MP0008260_abnormal_autophagy1.73922662
44MP0002429_abnormal_blood_cell1.70254748
45MP0001533_abnormal_skeleton_physiology1.70172420
46MP0008007_abnormal_cellular_replicative1.70079680
47MP0002419_abnormal_innate_immunity1.69154530
48MP0010352_gastrointestinal_tract_polyps1.65928745
49MP0005076_abnormal_cell_differentiation1.61717196
50MP0009278_abnormal_bone_marrow1.60055012
51MP0000465_gastrointestinal_hemorrhage1.59952479
52MP0000858_altered_metastatic_potential1.57933482
53MP0001853_heart_inflammation1.54987601
54MP0010234_abnormal_vibrissa_follicle1.52458980
55MP0002277_abnormal_respiratory_mucosa1.52406137
56MP0002998_abnormal_bone_remodeling1.51751661
57MP0002148_abnormal_hypersensitivity_rea1.47155827
58MP0001545_abnormal_hematopoietic_system1.46767804
59MP0005397_hematopoietic_system_phenotyp1.46767804
60MP0004381_abnormal_hair_follicle1.46690114
61MP0002006_tumorigenesis1.43216992
62MP0008004_abnormal_stomach_pH1.39497680
63MP0009764_decreased_sensitivity_to1.30962804
64MP0002796_impaired_skin_barrier1.30962643
65MP0001542_abnormal_bone_strength1.29855106
66MP0004808_abnormal_hematopoietic_stem1.29839049
67MP0004264_abnormal_extraembryonic_tissu1.29047371
68MP0000678_abnormal_parathyroid_gland1.27752713
69MP0001849_ear_inflammation1.26796761
70MP0005083_abnormal_biliary_tract1.23726943
71MP0001881_abnormal_mammary_gland1.21149460
72MP0003705_abnormal_hypodermis_morpholog1.19048595
73MP0005464_abnormal_platelet_physiology1.18539658
74MP0001243_abnormal_dermal_layer1.17864126
75MP0000609_abnormal_liver_physiology1.12797826
76MP0005409_darkened_coat_color1.10940042
77MP0003453_abnormal_keratinocyte_physiol1.07164379
78MP0001502_abnormal_circadian_rhythm1.05891251
79MP0004858_abnormal_nervous_system1.04524148
80MP0000490_abnormal_crypts_of1.03367958
81MP0005501_abnormal_skin_physiology1.02765118
82MP0008469_abnormal_protein_level1.02584538
83MP0002396_abnormal_hematopoietic_system1.00207823
84MP0003183_abnormal_peptide_metabolism0.98998042
85MP0003448_altered_tumor_morphology0.97456795
86MP0002132_abnormal_respiratory_system0.95909696
87MP0002060_abnormal_skin_morphology0.94656321
88MP0005164_abnormal_response_to0.91735068
89MP0003656_abnormal_erythrocyte_physiolo0.91732922
90MP0001216_abnormal_epidermal_layer0.91283165
91MP0002653_abnormal_ependyma_morphology0.89843914
92MP0002098_abnormal_vibrissa_morphology0.89604908
93MP0003091_abnormal_cell_migration0.88090919
94MP0003795_abnormal_bone_structure0.87856422
95MP0000681_abnormal_thyroid_gland0.86845193
96MP0001191_abnormal_skin_condition0.85233867
97MP0002136_abnormal_kidney_physiology0.84999794
98MP0005381_digestive/alimentary_phenotyp0.84039142
99MP0001348_abnormal_lacrimal_gland0.82674408
100MP0000470_abnormal_stomach_morphology0.80696553
101MP0005310_abnormal_salivary_gland0.80496725
102MP0000249_abnormal_blood_vessel0.80193815
103MP0004883_abnormal_blood_vessel0.80065967
104MP0002019_abnormal_tumor_incidence0.79710660
105MP0005390_skeleton_phenotype0.78794505
106MP0004782_abnormal_surfactant_physiolog0.78429022
107MP0002877_abnormal_melanocyte_morpholog0.77575118
108MP0000604_amyloidosis0.77113208
109MP0003638_abnormal_response/metabolism_0.75049540
110MP0000343_altered_response_to0.74078957
111MP0009763_increased_sensitivity_to0.72302014
112MP0002254_reproductive_system_inflammat0.71781409
113MP0000733_abnormal_muscle_development0.60726757
114MP0003075_altered_response_to0.58972520
115MP0003045_fibrosis0.56924795
116MP0000367_abnormal_coat/_hair0.55486903
117MP0000477_abnormal_intestine_morphology0.54847984
118MP0000350_abnormal_cell_proliferation0.54757642
119MP0005023_abnormal_wound_healing0.54371903
120MP0005166_decreased_susceptibility_to0.54338239
121MP0003566_abnormal_cell_adhesion0.54259893
122MP0008995_early_reproductive_senescence0.53551193
123MP0003077_abnormal_cell_cycle0.53398035
124MP0001663_abnormal_digestive_system0.52953529
125MP0009931_abnormal_skin_appearance0.52891033
126MP0009840_abnormal_foam_cell0.51587845
127MP0003329_amyloid_beta_deposits0.48161313
128MP0009765_abnormal_xenobiotic_induced0.47583202
129MP0005621_abnormal_cell_physiology0.45141436

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)8.64340140
2Increased density of long bones (HP:0006392)7.58446444
3Retrobulbar optic neuritis (HP:0100654)6.25451558
4Optic neuritis (HP:0100653)6.25451558
5Persistence of primary teeth (HP:0006335)6.06913723
6Elevated erythrocyte sedimentation rate (HP:0003565)6.05978768
7Orchitis (HP:0100796)5.71073191
8Myositis (HP:0100614)5.70445617
9IgM deficiency (HP:0002850)4.89108797
10Keratoconjunctivitis sicca (HP:0001097)4.49392692
11Severe combined immunodeficiency (HP:0004430)4.38904063
12T lymphocytopenia (HP:0005403)4.38713404
13Nasal polyposis (HP:0100582)4.20833985
14Abnormality of T cell number (HP:0011839)4.13978714
15Keratoconjunctivitis (HP:0001096)4.05935137
16IgG deficiency (HP:0004315)4.01220792
17Thyroiditis (HP:0100646)3.91683721
18Pulmonary infiltrates (HP:0002113)3.90654197
19Arterial thrombosis (HP:0004420)3.90018939
20Combined immunodeficiency (HP:0005387)3.89689505
21Abnormality of macrophages (HP:0004311)3.71875035
22Recurrent bronchitis (HP:0002837)3.68694948
23Prolonged bleeding time (HP:0003010)3.54835297
24Abnormality of T cells (HP:0002843)3.53706621
25Abnormality of the nasal mucosa (HP:0000433)3.51286011
26Abnormality of eosinophils (HP:0001879)3.49126251
27Hemoptysis (HP:0002105)3.48685681
28Recurrent bacterial skin infections (HP:0005406)3.36707414
29Recurrent abscess formation (HP:0002722)3.35563011
30Recurrent fungal infections (HP:0002841)3.27900216
31Gastrointestinal infarctions (HP:0005244)3.27809469
32Vasculitis (HP:0002633)3.22616088
33Increased cerebral lipofuscin (HP:0011813)3.08473076
34Petechiae (HP:0000967)3.05551149
35Depressed nasal tip (HP:0000437)3.04022896
36Eczematoid dermatitis (HP:0000976)3.01519713
37Increased neuronal autofluorescent lipopigment (HP:0002074)2.97395678
38Mediastinal lymphadenopathy (HP:0100721)2.94569995
39Joint swelling (HP:0001386)2.92487096
40Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.92268694
41IgA deficiency (HP:0002720)2.92156881
42Leukocytosis (HP:0001974)2.91847137
43Pulmonary embolism (HP:0002204)2.89500427
44Chronic diarrhea (HP:0002028)2.81409553
45Broad face (HP:0000283)2.81211319
46Urticaria (HP:0001025)2.77077243
47Abnormality of B cell number (HP:0010975)2.76111181
48B lymphocytopenia (HP:0010976)2.76111181
49Chronic otitis media (HP:0000389)2.70813185
50Abnormality of T cell physiology (HP:0011840)2.70268106
51Chronic obstructive pulmonary disease (HP:0006510)2.67476044
52Obstructive lung disease (HP:0006536)2.67476044
53Cellulitis (HP:0100658)2.66680911
54Epistaxis (HP:0000421)2.65890818
55Recurrent sinusitis (HP:0011108)2.61422861
56Anorexia (HP:0002039)2.59937042
57Encephalitis (HP:0002383)2.57544635
58Increased IgM level (HP:0003496)2.55981579
59Gastrointestinal stroma tumor (HP:0100723)2.52225740
60Autoimmune thrombocytopenia (HP:0001973)2.51490321
61Gangrene (HP:0100758)2.50671328
62Premature loss of primary teeth (HP:0006323)2.48159895
63Meningitis (HP:0001287)2.43015082
64Milia (HP:0001056)2.37406144
65Pustule (HP:0200039)2.35837133
66Lymphopenia (HP:0001888)2.35098663
67Increased IgE level (HP:0003212)2.34269911
68Lymphoma (HP:0002665)2.32730661
69Abnormality of the fingertips (HP:0001211)2.32618683
70Chronic mucocutaneous candidiasis (HP:0002728)2.32590742
71Recurrent cutaneous fungal infections (HP:0011370)2.32590742
72Recurrent viral infections (HP:0004429)2.30298712
73Thick nail (HP:0001805)2.29890507
74Abnormality of glycolipid metabolism (HP:0010969)2.25212713
75Abnormality of liposaccharide metabolism (HP:0010968)2.25212713
76Abnormality of glycosphingolipid metabolism (HP:0004343)2.25212713
77Abnormality of cells of the lymphoid lineage (HP:0012140)2.25009838
78Increased serum ferritin (HP:0003281)2.24053862
79Emphysema (HP:0002097)2.23729836
80Chest pain (HP:0100749)2.23646479
81Abnormality of the pericardium (HP:0001697)2.23356544
82Abnormality of the nasal septum (HP:0000419)2.21880242
83Panhypogammaglobulinemia (HP:0003139)2.21075952
84Interstitial pulmonary disease (HP:0006530)2.19686347
85Eosinophilia (HP:0001880)2.19183750
86Malnutrition (HP:0004395)2.17876343
87Abnormal platelet volume (HP:0011876)2.17563213
88Abnormal delayed hypersensitivity skin test (HP:0002963)2.16023215
89Segmental peripheral demyelination/remyelination (HP:0003481)2.13986614
90Abnormality of the pleura (HP:0002103)2.12929427
91Polygenic inheritance (HP:0010982)2.11750606
92Obstructive sleep apnea (HP:0002870)2.11279349
93Osteomyelitis (HP:0002754)2.09429975
94Hypochromic anemia (HP:0001931)2.08714939
95Nail dystrophy (HP:0008404)2.08010593
96Cerebral aneurysm (HP:0004944)2.06245505
97Thrombophlebitis (HP:0004418)2.06221506
98Abnormality of the endocardium (HP:0004306)2.05915030
99Dysostosis multiplex (HP:0000943)2.05554872
100Autoimmune hemolytic anemia (HP:0001890)2.04758924
101Keratitis (HP:0000491)2.04607667
102Aortic dissection (HP:0002647)2.04523681
103Hepatitis (HP:0012115)2.04441187
104Aortic aneurysm (HP:0004942)2.04300106
105Easy fatigability (HP:0003388)2.03748226
106Hemorrhage of the eye (HP:0011885)2.03162327
107Abnormality of the prostate (HP:0008775)2.02784525
108Impaired platelet aggregation (HP:0003540)2.02332361
109Abnormal platelet function (HP:0011869)2.02332361
110Abnormality of nail color (HP:0100643)2.02168396
111Abnormal blistering of the skin (HP:0008066)2.02066865
112Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.01870201
113Spontaneous hematomas (HP:0007420)2.01459122
114Flattened epiphyses (HP:0003071)2.01162184
115Purpura (HP:0000979)2.00928732
116Abnormality of iron homeostasis (HP:0011031)1.99574429
117Glomerulopathy (HP:0100820)1.99574082
118Recurrent skin infections (HP:0001581)1.99257813
119Pancytopenia (HP:0001876)1.96797854
120Mitral valve prolapse (HP:0001634)1.93723105
121Recurrent gram-negative bacterial infections (HP:0005420)1.92520519
122Bronchitis (HP:0012387)1.92506194
123Inflammation of the large intestine (HP:0002037)1.92401181
124Thin bony cortex (HP:0002753)1.91918824
125Arthralgia (HP:0002829)1.91619428
126Hypertensive crisis (HP:0100735)1.91242697
127Loss of speech (HP:0002371)1.90471196
128Hypergammaglobulinemia (HP:0010702)1.90387453
129Rhinitis (HP:0012384)1.90078318
130Gingival bleeding (HP:0000225)1.89126225
131Dilatation of the ascending aorta (HP:0005111)1.88810492
132Gastrointestinal inflammation (HP:0004386)1.88542313
133Papilloma (HP:0012740)1.86881322
134Verrucae (HP:0200043)1.86881322
135Abnormal albumin level (HP:0012116)1.86525691
136Hypoalbuminemia (HP:0003073)1.86525691
137Distal lower limb amyotrophy (HP:0008944)1.86277548
138Episodic fever (HP:0001954)1.85813847
139Slow saccadic eye movements (HP:0000514)1.85556828
140Arterial tortuosity (HP:0005116)1.82356662
141Colitis (HP:0002583)1.80811388
142Ureteral stenosis (HP:0000071)1.80294579
143Gingivitis (HP:0000230)1.78863527
144Cheilitis (HP:0100825)1.78675848
145Granulocytopenia (HP:0001913)1.77227137
146Skin ulcer (HP:0200042)1.76943605
147Polyneuropathy (HP:0001271)1.76728628
148Deep palmar crease (HP:0006191)1.75657679
149Vertebral arch anomaly (HP:0008438)1.75558670
150Onion bulb formation (HP:0003383)1.75306035
151Diplopia (HP:0000651)1.74660614
152Abnormality of binocular vision (HP:0011514)1.74660614
153Acrocyanosis (HP:0001063)1.74515561
154Hypertriglyceridemia (HP:0002155)1.73043382
155Bruising susceptibility (HP:0000978)1.72859992
156Difficulty climbing stairs (HP:0003551)1.71469935
157Polycythemia (HP:0001901)1.70737724
158Plantar hyperkeratosis (HP:0007556)1.66531097
159Sepsis (HP:0100806)1.66387349
160Menorrhagia (HP:0000132)1.65558909

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.85421454
2MAP4K14.44360925
3ITK3.98922154
4IRAK33.37952531
5TAOK33.30231682
6MAP3K143.29080201
7PRPF4B3.17737147
8EPHA22.63520426
9TSSK62.52024870
10GRK62.49114502
11TBK12.44419595
12STK102.37504719
13JAK12.33674569
14EPHB12.25998207
15TEC2.21050211
16IKBKE2.19766619
17RIPK42.18171683
18JAK31.97658400
19FGFR41.95300540
20IKBKB1.94153057
21MAP3K101.93136680
22TYK21.89926002
23CHUK1.88312826
24BTK1.84878166
25EPHA31.83215396
26RPS6KA41.81076472
27NLK1.77764754
28ZAP701.62144518
29EEF2K1.59263945
30TAOK21.48696340
31TRIB31.47015221
32PIM11.44443643
33HCK1.43675191
34LMTK21.36033486
35MST41.31903722
36TNK21.30266618
37PKN21.29478006
38TGFBR21.27795267
39MARK21.26756387
40LCK1.24732097
41PTK61.24681284
42MAP3K11.22902692
43SMG11.19084071
44MST1R1.18451472
45ICK1.17523850
46IRAK21.15678681
47TYRO31.14280207
48MAP3K131.13964947
49SIK31.10218502
50FGFR31.10159170
51JAK21.09119714
52MAP2K31.08662492
53MARK31.07740619
54MAP3K110.96728063
55CSK0.96018186
56MAPK150.93558437
57TESK10.91979210
58MATK0.91067904
59EPHB20.90218568
60RPS6KC10.87794535
61RPS6KL10.87794535
62GSK3A0.86813618
63TAOK10.86458110
64RPS6KA20.83533877
65SYK0.83114493
66IRAK10.83050352
67MELK0.82346756
68RPS6KA50.81842199
69MAP2K20.81778400
70RPS6KA60.79576805
71PRKCH0.78573428
72LRRK20.78280418
73CDK120.78239527
74CDC42BPA0.78212058
75PKN10.77559478
76PRKCQ0.75611021
77PDPK10.75107154
78SIK20.74386702
79PTK2B0.71597365
80RPS6KA10.70157905
81SIK10.67230440
82PRKG20.66371991
83STK380.66317675
84PRKD30.66171617
85KSR20.65874247
86CSF1R0.65715361
87HIPK20.64385221
88PAK40.64095121
89ERN10.61950522
90CDK40.60459915
91MAP3K70.60219501
92MTOR0.56941703
93MAP3K30.53786061
94PDGFRB0.52959998
95ALK0.50007803
96IRAK40.48948261
97NME20.48032188
98RIPK10.46769413
99MAPK110.45547490
100MAP3K60.45442854
101MAPK70.44506771
102FGR0.43977240
103CLK10.43364431
104STK110.42653811
105MOS0.41708818
106MAP3K80.41439493
107FES0.41199232
108MAPKAPK50.41128906
109TESK20.39208404
110TRPM70.37634777
111DDR20.37457590
112DMPK0.37195251
113MAP2K60.37016482
114MAPK120.36479999
115RET0.35862112
116PRKD20.35485929
117TTN0.34220278
118MAPK30.33263425
119LYN0.33150674
120DYRK1B0.32803651
121MAPK80.32099582
122IGF1R0.30446911
123BRD40.29327396
124CDK90.29183779
125INSR0.28109325
126KIT0.27335108
127MAPK10.27136224
128PDK10.27135233
129PTK20.25819227
130MAPK40.25638087
131PIM20.24655448
132MAPKAPK20.24194654
133CDK60.23732574
134BMX0.23313116
135STK240.22210400
136BLK0.19023713
137FGFR10.18467013

Predicted pathways (KEGG)

RankGene SetZ-score
1Inflammatory bowel disease (IBD)_Homo sapiens_hsa053214.13008125
2Primary immunodeficiency_Homo sapiens_hsa053403.62501569
3NF-kappa B signaling pathway_Homo sapiens_hsa040643.47879345
4T cell receptor signaling pathway_Homo sapiens_hsa046603.45875044
5Osteoclast differentiation_Homo sapiens_hsa043803.40861657
6Measles_Homo sapiens_hsa051622.77941465
7TNF signaling pathway_Homo sapiens_hsa046682.57218384
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.35847442
9NOD-like receptor signaling pathway_Homo sapiens_hsa046212.28154087
10B cell receptor signaling pathway_Homo sapiens_hsa046622.25969468
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.08683260
12Leishmaniasis_Homo sapiens_hsa051402.08184020
13Antigen processing and presentation_Homo sapiens_hsa046122.05261372
14Toxoplasmosis_Homo sapiens_hsa051451.91166887
15Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.87454669
16Jak-STAT signaling pathway_Homo sapiens_hsa046301.84351444
17Circadian rhythm_Homo sapiens_hsa047101.83225953
18Acute myeloid leukemia_Homo sapiens_hsa052211.80824189
19Allograft rejection_Homo sapiens_hsa053301.66486838
20Prolactin signaling pathway_Homo sapiens_hsa049171.61008480
21Other glycan degradation_Homo sapiens_hsa005111.60275453
22Legionellosis_Homo sapiens_hsa051341.56859042
23Chronic myeloid leukemia_Homo sapiens_hsa052201.54330986
24Hepatitis B_Homo sapiens_hsa051611.48418804
25Graft-versus-host disease_Homo sapiens_hsa053321.42034980
26RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.42027831
27Herpes simplex infection_Homo sapiens_hsa051681.38450798
28AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.32973585
29Influenza A_Homo sapiens_hsa051641.31774690
30Viral myocarditis_Homo sapiens_hsa054161.31425116
31Leukocyte transendothelial migration_Homo sapiens_hsa046701.31035442
32Epstein-Barr virus infection_Homo sapiens_hsa051691.30297866
33Chemokine signaling pathway_Homo sapiens_hsa040621.30068144
34Shigellosis_Homo sapiens_hsa051311.25755186
35Apoptosis_Homo sapiens_hsa042101.25570971
36Pancreatic cancer_Homo sapiens_hsa052121.23823170
37VEGF signaling pathway_Homo sapiens_hsa043701.22344760
38Neurotrophin signaling pathway_Homo sapiens_hsa047221.17592431
39Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16943886
40HTLV-I infection_Homo sapiens_hsa051661.16264310
41Colorectal cancer_Homo sapiens_hsa052101.14642337
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.13930902
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.12590721
44Bladder cancer_Homo sapiens_hsa052191.12329012
45Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.11561353
46Glycosaminoglycan degradation_Homo sapiens_hsa005311.07432541
47MAPK signaling pathway_Homo sapiens_hsa040101.04693647
48Small cell lung cancer_Homo sapiens_hsa052221.03884425
49Lysosome_Homo sapiens_hsa041421.02437800
50Adipocytokine signaling pathway_Homo sapiens_hsa049201.00828864
51Autoimmune thyroid disease_Homo sapiens_hsa053200.99788725
52Hematopoietic cell lineage_Homo sapiens_hsa046400.98832494
53Transcriptional misregulation in cancer_Homo sapiens_hsa052020.98048476
54Renal cell carcinoma_Homo sapiens_hsa052110.91230601
55Toll-like receptor signaling pathway_Homo sapiens_hsa046200.90065459
56Hepatitis C_Homo sapiens_hsa051600.87908793
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87059956
58Platelet activation_Homo sapiens_hsa046110.86429027
59FoxO signaling pathway_Homo sapiens_hsa040680.83039198
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81379082
61Phagosome_Homo sapiens_hsa041450.81009580
62Viral carcinogenesis_Homo sapiens_hsa052030.80935824
63African trypanosomiasis_Homo sapiens_hsa051430.80366742
64Amoebiasis_Homo sapiens_hsa051460.75660676
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74898084
66Insulin resistance_Homo sapiens_hsa049310.74074574
67GnRH signaling pathway_Homo sapiens_hsa049120.71931122
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70099220
69Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68301870
70Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67676679
71Salmonella infection_Homo sapiens_hsa051320.66660135
72Non-small cell lung cancer_Homo sapiens_hsa052230.64947271
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63549287
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63112644
75Notch signaling pathway_Homo sapiens_hsa043300.63012993
76Dorso-ventral axis formation_Homo sapiens_hsa043200.62940345
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61573512
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61394660
79Type II diabetes mellitus_Homo sapiens_hsa049300.61153390
80Tuberculosis_Homo sapiens_hsa051520.60153427
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58200881
82Endometrial cancer_Homo sapiens_hsa052130.57899157
83Malaria_Homo sapiens_hsa051440.56459177
84HIF-1 signaling pathway_Homo sapiens_hsa040660.56289920
85Focal adhesion_Homo sapiens_hsa045100.56200676
86p53 signaling pathway_Homo sapiens_hsa041150.55881897
87mTOR signaling pathway_Homo sapiens_hsa041500.55696395
88Rheumatoid arthritis_Homo sapiens_hsa053230.55543206
89* Endocytosis_Homo sapiens_hsa041440.55266125
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.55183908
91Prostate cancer_Homo sapiens_hsa052150.52555675
92Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.52541166
93Rap1 signaling pathway_Homo sapiens_hsa040150.52327384
94Estrogen signaling pathway_Homo sapiens_hsa049150.46695309
95Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44432666
96Pathways in cancer_Homo sapiens_hsa052000.44356322
97Pertussis_Homo sapiens_hsa051330.43351018
98MicroRNAs in cancer_Homo sapiens_hsa052060.42594232
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.42527372
100Spliceosome_Homo sapiens_hsa030400.41968894
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.40704712
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40509158
103Staphylococcus aureus infection_Homo sapiens_hsa051500.40302107
104Type I diabetes mellitus_Homo sapiens_hsa049400.37723218
105Prion diseases_Homo sapiens_hsa050200.37235854
106Aldosterone synthesis and secretion_Homo sapiens_hsa049250.36929270
107Proteoglycans in cancer_Homo sapiens_hsa052050.36634502
108Asthma_Homo sapiens_hsa053100.35908910
109ErbB signaling pathway_Homo sapiens_hsa040120.35760540
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.35453700
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.34014324
112Choline metabolism in cancer_Homo sapiens_hsa052310.33451688
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32845834
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.32031758
115Thyroid cancer_Homo sapiens_hsa052160.31348413
116Phospholipase D signaling pathway_Homo sapiens_hsa040720.31247935
117Inositol phosphate metabolism_Homo sapiens_hsa005620.29929218
118Insulin signaling pathway_Homo sapiens_hsa049100.28759350
119Central carbon metabolism in cancer_Homo sapiens_hsa052300.26475059

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