VPS37D

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act6.34236677
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.47002157
3pyrimidine nucleobase catabolic process (GO:0006208)5.43469014
4regulation of glutamate receptor signaling pathway (GO:1900449)5.24000307
5synaptic vesicle maturation (GO:0016188)5.14548813
6layer formation in cerebral cortex (GO:0021819)5.02928647
7axonal fasciculation (GO:0007413)4.88269189
8locomotory exploration behavior (GO:0035641)4.83289583
9negative regulation of synaptic transmission, glutamatergic (GO:0051967)4.68449246
10synaptic vesicle exocytosis (GO:0016079)4.67902350
11cellular response to pH (GO:0071467)4.65775365
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.64453472
13spinal cord motor neuron differentiation (GO:0021522)4.62312351
14synaptic transmission, glutamatergic (GO:0035249)4.61540143
15vocalization behavior (GO:0071625)4.55267740
16dendritic spine morphogenesis (GO:0060997)4.51416752
17negative regulation of cell size (GO:0045792)4.50683019
18ionotropic glutamate receptor signaling pathway (GO:0035235)4.50614201
19positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.48617298
20neuron recognition (GO:0008038)4.45509483
21nucleobase catabolic process (GO:0046113)4.33302269
22neuron cell-cell adhesion (GO:0007158)4.19846421
23behavioral response to nicotine (GO:0035095)4.18421844
24male sex determination (GO:0030238)4.17783229
25cell migration in hindbrain (GO:0021535)4.16577977
26protein localization to synapse (GO:0035418)4.14653728
27regulation of synaptic vesicle exocytosis (GO:2000300)4.04595146
28glutamate secretion (GO:0014047)4.00526749
29G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.99461183
30substrate-independent telencephalic tangential migration (GO:0021826)3.97481568
31substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.97481568
32adult walking behavior (GO:0007628)3.95975254
33exploration behavior (GO:0035640)3.87157843
34thalamus development (GO:0021794)3.79372217
35synaptic vesicle docking involved in exocytosis (GO:0016081)3.78244984
36negative regulation of microtubule polymerization (GO:0031115)3.78070318
37regulation of NFAT protein import into nucleus (GO:0051532)3.74945653
38neuron-neuron synaptic transmission (GO:0007270)3.73888940
39cerebellum development (GO:0021549)3.70890355
40positive regulation of synapse maturation (GO:0090129)3.69117183
41spinal cord association neuron differentiation (GO:0021527)3.61506412
42glutamate receptor signaling pathway (GO:0007215)3.59432633
43postsynaptic membrane organization (GO:0001941)3.57859110
44maturation of SSU-rRNA (GO:0030490)3.57465472
45transmission of nerve impulse (GO:0019226)3.55228051
46regulation of neuronal synaptic plasticity (GO:0048168)3.52542674
47gamma-aminobutyric acid transport (GO:0015812)3.50259857
48neurotransmitter secretion (GO:0007269)3.49907802
49regulation of synapse structural plasticity (GO:0051823)3.48736706
50regulation of synaptic vesicle transport (GO:1902803)3.45221645
51dendrite morphogenesis (GO:0048813)3.41808362
52axon extension (GO:0048675)3.39829828
53neuronal action potential propagation (GO:0019227)3.37185844
54cerebellar Purkinje cell layer development (GO:0021680)3.32121344
55regulation of long-term neuronal synaptic plasticity (GO:0048169)3.30547877
56central nervous system projection neuron axonogenesis (GO:0021952)3.29498559
57embryonic retina morphogenesis in camera-type eye (GO:0060059)3.27533619
58cell proliferation in forebrain (GO:0021846)3.25791181
59retinal ganglion cell axon guidance (GO:0031290)3.25552478
60presynaptic membrane organization (GO:0097090)3.21150892
61positive regulation of axon extension (GO:0045773)3.17946038
62ribosomal small subunit biogenesis (GO:0042274)3.09760778
63cerebral cortex radially oriented cell migration (GO:0021799)3.08937723
64membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.08158284
65activation of protein kinase A activity (GO:0034199)3.07751293
66neuron projection extension (GO:1990138)3.05086370
67urogenital system development (GO:0001655)3.03849720
68proline transport (GO:0015824)3.03293971
69neuronal ion channel clustering (GO:0045161)3.03045728
70neurotransmitter catabolic process (GO:0042135)3.01851639
71cell differentiation in spinal cord (GO:0021515)3.01677981
72regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.98160917
73positive regulation of membrane potential (GO:0045838)2.96995829
74mechanosensory behavior (GO:0007638)2.96173424
75negative regulation of axon extension involved in axon guidance (GO:0048843)2.94668707
76synapse assembly (GO:0007416)2.94082476
77cell communication by electrical coupling (GO:0010644)2.93388543
78neuron projection extension involved in neuron projection guidance (GO:1902284)2.93372095
79axon extension involved in axon guidance (GO:0048846)2.93372095
80long-term memory (GO:0007616)2.92918231
81positive regulation of synaptic transmission, GABAergic (GO:0032230)2.89970948
82body morphogenesis (GO:0010171)2.89875103
83neuromuscular process controlling balance (GO:0050885)2.86400671
84regulation of dendritic spine morphogenesis (GO:0061001)2.85703286
85establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.85347954
86mitochondrion transport along microtubule (GO:0047497)2.85347954
87clathrin coat assembly (GO:0048268)2.83139469
88spinal cord development (GO:0021510)2.82391892
89regulation of excitatory postsynaptic membrane potential (GO:0060079)2.81884791
90dendritic spine organization (GO:0097061)2.81225256
91central nervous system myelination (GO:0022010)2.81026463
92axon ensheathment in central nervous system (GO:0032291)2.81026463
93negative regulation of axon extension (GO:0030517)2.80235564
94regulation of axon extension involved in axon guidance (GO:0048841)2.79986255
95regulation of synaptic transmission, glutamatergic (GO:0051966)2.79753712
96positive regulation of gastrulation (GO:2000543)2.78586408
97regulation of axon extension (GO:0030516)2.77709988
98neurotransmitter-gated ion channel clustering (GO:0072578)2.77690396
99ephrin receptor signaling pathway (GO:0048013)2.77660672
100regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.77285960
101forebrain neuron development (GO:0021884)2.75736639
102ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.74226985
103positive regulation of synapse assembly (GO:0051965)2.72498864
104response to auditory stimulus (GO:0010996)2.72315382
105cerebellar Purkinje cell differentiation (GO:0021702)2.72115796
106negative regulation of catenin import into nucleus (GO:0035414)2.71871844
107regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.71338991
108prepulse inhibition (GO:0060134)2.71026947
109innervation (GO:0060384)2.69887863
110regulation of early endosome to late endosome transport (GO:2000641)2.69839930
111cranial nerve morphogenesis (GO:0021602)2.69428278
112dendrite development (GO:0016358)2.68777412
113short-term memory (GO:0007614)2.68728819
114microtubule severing (GO:0051013)2.68641267
115hippocampus development (GO:0021766)2.68473656
116response to pheromone (GO:0019236)2.67820489
117regulation of neurotransmitter secretion (GO:0046928)2.67816574
118membrane hyperpolarization (GO:0060081)2.67223110
119somite development (GO:0061053)2.67217550
120auditory behavior (GO:0031223)2.66885951
121head development (GO:0060322)2.66775215
122regulation of vesicle fusion (GO:0031338)2.66387629
123neurotransmitter transport (GO:0006836)2.66159292
124regulation of postsynaptic membrane potential (GO:0060078)2.66063333
125regulation of synaptic plasticity (GO:0048167)2.65642173
126regulation of synapse maturation (GO:0090128)2.65391521
127pattern specification involved in kidney development (GO:0061004)2.65056391
128establishment of mitochondrion localization (GO:0051654)2.65041169
129negative regulation of axon guidance (GO:1902668)2.63663252
130behavioral defense response (GO:0002209)2.62486354
131behavioral fear response (GO:0001662)2.62486354
132synaptic vesicle endocytosis (GO:0048488)2.62055841
133regulation of axon guidance (GO:1902667)2.61651249
134telencephalon development (GO:0021537)2.60753031
135cerebellar granule cell differentiation (GO:0021707)2.60234492
136presynaptic membrane assembly (GO:0097105)2.60149740
137sex determination (GO:0007530)2.59837710
138nonmotile primary cilium assembly (GO:0035058)2.59753982
139retina layer formation (GO:0010842)2.57624386
140camera-type eye morphogenesis (GO:0048593)2.56749361
141synaptic transmission, cholinergic (GO:0007271)2.56293231
142bone trabecula formation (GO:0060346)2.55728072
143neuron migration (GO:0001764)2.52711536
144cell differentiation in hindbrain (GO:0021533)2.52699302
145olfactory bulb development (GO:0021772)2.47584851
146forebrain neuron differentiation (GO:0021879)2.47291214
147cell-cell junction maintenance (GO:0045217)2.44288438
148protein import into peroxisome matrix (GO:0016558)2.43390877
149central nervous system neuron development (GO:0021954)2.40913872
150cornea development in camera-type eye (GO:0061303)2.39942497
151adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.39319914
152response to dietary excess (GO:0002021)2.39223128
153calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.36530644
154positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.34830631
155convergent extension (GO:0060026)2.34194305
156synapse organization (GO:0050808)2.34166197
157positive regulation of growth hormone secretion (GO:0060124)2.34055341

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.41928299
2JARID2_20064375_ChIP-Seq_MESCs_Mouse3.37666074
3JARID2_20075857_ChIP-Seq_MESCs_Mouse3.13213806
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.11139738
5RNF2_18974828_ChIP-Seq_MESCs_Mouse3.05320042
6EZH2_18974828_ChIP-Seq_MESCs_Mouse3.05320042
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.95045624
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.93711430
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.80538219
10CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.72487495
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.70165196
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.68360925
13* EZH2_27294783_Chip-Seq_ESCs_Mouse2.65859100
14SUZ12_27294783_Chip-Seq_ESCs_Mouse2.62940216
15EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.62882599
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58346045
17REST_21632747_ChIP-Seq_MESCs_Mouse2.55705709
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.52672091
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.49315641
20RARB_27405468_Chip-Seq_BRAIN_Mouse2.27502420
21ZFP281_18757296_ChIP-ChIP_E14_Mouse2.25699694
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.22905643
23DROSHA_22980978_ChIP-Seq_HELA_Human2.22069857
24RBPJ_22232070_ChIP-Seq_NCS_Mouse2.17339188
25GBX2_23144817_ChIP-Seq_PC3_Human2.15408593
26RNF2_27304074_Chip-Seq_ESCs_Mouse2.13365996
27TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.13121714
28REST_18959480_ChIP-ChIP_MESCs_Mouse2.10673643
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.08781821
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.94345534
31PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.82932237
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.76064025
33RING1B_27294783_Chip-Seq_ESCs_Mouse1.75552096
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70216874
35ZNF274_21170338_ChIP-Seq_K562_Hela1.65372390
36RING1B_27294783_Chip-Seq_NPCs_Mouse1.64855224
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.61772313
38HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.61159123
39ZFP281_27345836_Chip-Seq_ESCs_Mouse1.60662947
40THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.59863846
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.57566046
42* KDM2B_26808549_Chip-Seq_K562_Human1.55627137
43* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.53537371
44OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.51131445
45ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.46059261
46RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.44300938
47CTCF_27219007_Chip-Seq_Bcells_Human1.40989038
48ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.40182322
49TP53_20018659_ChIP-ChIP_R1E_Mouse1.38325170
50DNAJC2_21179169_ChIP-ChIP_NT2_Human1.38040673
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.37803464
52LXR_22292898_ChIP-Seq_THP-1_Human1.35845646
53EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.30604912
54SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.28517160
55TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23826172
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.22025548
57STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.20813119
58ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.20572507
59CTBP2_25329375_ChIP-Seq_LNCAP_Human1.18589794
60KDM2B_26808549_Chip-Seq_SUP-B15_Human1.17407910
61AR_21572438_ChIP-Seq_LNCaP_Human1.15337508
62CREB1_26743006_Chip-Seq_LNCaP_Human1.12896721
63KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10741428
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10007929
65* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.08756790
66P68_20966046_ChIP-Seq_HELA_Human1.08572103
67TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07835947
68SRY_22984422_ChIP-ChIP_TESTIS_Rat1.07081744
69WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05248329
70ZNF263_19887448_ChIP-Seq_K562_Human1.03996966
71ESR1_20079471_ChIP-ChIP_T-47D_Human1.03172081
72PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03126384
73TET1_21490601_ChIP-Seq_MESCs_Mouse1.02581103
74* TET1_21451524_ChIP-Seq_MESCs_Mouse1.01821648
75NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.99590476
76RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99330329
77VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.98267428
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.97571586
79CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96219871
80MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.95101727
81RNF2_27304074_Chip-Seq_NSC_Mouse0.95004875
82GATA1_26923725_Chip-Seq_HPCs_Mouse0.94705756
83CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.94197132
84KDM2B_26808549_Chip-Seq_JURKAT_Human0.94133088
85POU5F1_16518401_ChIP-PET_MESCs_Mouse0.93158863
86TP53_22127205_ChIP-Seq_IMR90_Human0.92641934
87DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92541400
88AR_19668381_ChIP-Seq_PC3_Human0.92513466
89SMAD4_21741376_ChIP-Seq_HESCs_Human0.91748035
90CTBP1_25329375_ChIP-Seq_LNCAP_Human0.91305822
91* SMC4_20622854_ChIP-Seq_HELA_Human0.90527915
92SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90292571
93ESR1_15608294_ChIP-ChIP_MCF-7_Human0.89989194
94* SOX3_22085726_ChIP-Seq_NPCs_Mouse0.89602810
95ISL1_27105846_Chip-Seq_CPCs_Mouse0.89343952
96SMAD3_21741376_ChIP-Seq_ESCs_Human0.88454238
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.88386196
98SOX2_21211035_ChIP-Seq_LN229_Gbm0.88141211
99FOXP1_21924763_ChIP-Seq_HESCs_Human0.87107600
100SOX2_18555785_ChIP-Seq_MESCs_Mouse0.86538832
101SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86524912
102IGF1R_20145208_ChIP-Seq_DFB_Human0.86321578
103OCT4_19829295_ChIP-Seq_ESCs_Human0.86133996
104SMAD3_21741376_ChIP-Seq_EPCs_Human0.84229528
105* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.84048951
106POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.83652141
107TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83652141
108KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.82235448
109TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.82213112
110KDM2B_26808549_Chip-Seq_DND41_Human0.81994833
111YAP1_20516196_ChIP-Seq_MESCs_Mouse0.81421353
112SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.80925722
113TRIM28_21343339_ChIP-Seq_HEK293_Human0.79382137
114KLF4_19829295_ChIP-Seq_ESCs_Human0.79189973
115PHF8_20622854_ChIP-Seq_HELA_Human0.78752330
116MYC_27129775_Chip-Seq_CORNEA_Mouse0.78736922
117SOX2_16153702_ChIP-ChIP_HESCs_Human0.78644387
118* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.77924036
119ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.76615075
120TOP2B_26459242_ChIP-Seq_MCF-7_Human0.76583294
121E2F1_20622854_ChIP-Seq_HELA_Human0.75981889
122CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.75934131
123MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.75112127
124SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.74947882
125ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.74545282
126CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.74391566
127TP63_19390658_ChIP-ChIP_HaCaT_Human0.74176866
128RUNX1_26923725_Chip-Seq_HPCs_Mouse0.73547752
129SA1_27219007_Chip-Seq_ERYTHROID_Human0.73516200
130SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73199572
131NR3C1_23031785_ChIP-Seq_PC12_Mouse0.72654941
132CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.72575186
133* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.72384419
134SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.72138935

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.67319540
2MP0006292_abnormal_olfactory_placode4.93633134
3MP0003635_abnormal_synaptic_transmissio3.71989831
4MP0003880_abnormal_central_pattern3.62243273
5MP0004270_analgesia3.01015824
6MP0002063_abnormal_learning/memory/cond2.93411550
7MP0000778_abnormal_nervous_system2.67661575
8MP0003122_maternal_imprinting2.65978295
9MP0005423_abnormal_somatic_nervous2.56240445
10MP0004858_abnormal_nervous_system2.45111012
11MP0009745_abnormal_behavioral_response2.43415399
12MP0002064_seizures2.36116914
13MP0003283_abnormal_digestive_organ2.25963350
14MP0002572_abnormal_emotion/affect_behav2.19137986
15MP0001968_abnormal_touch/_nociception2.17312728
16MP0009046_muscle_twitch2.15409239
17MP0002734_abnormal_mechanical_nocicepti2.13604811
18MP0009379_abnormal_foot_pigmentation2.11638545
19MP0002184_abnormal_innervation2.11319059
20MP0010030_abnormal_orbit_morphology2.06340192
21MP0001486_abnormal_startle_reflex1.90154059
22MP0004811_abnormal_neuron_physiology1.87950245
23MP0006276_abnormal_autonomic_nervous1.84118862
24MP0002272_abnormal_nervous_system1.80625186
25MP0000955_abnormal_spinal_cord1.78167059
26MP0002733_abnormal_thermal_nociception1.76172550
27MP0000566_synostosis1.75284620
28MP0005623_abnormal_meninges_morphology1.70536974
29MP0002557_abnormal_social/conspecific_i1.69342352
30MP0002909_abnormal_adrenal_gland1.67995638
31MP0001440_abnormal_grooming_behavior1.66535790
32MP0003136_yellow_coat_color1.64051632
33MP0002882_abnormal_neuron_morphology1.58452379
34MP0001984_abnormal_olfaction1.58256696
35MP0002736_abnormal_nociception_after1.56036497
36MP0002163_abnormal_gland_morphology1.54231093
37MP0002067_abnormal_sensory_capabilities1.51233848
38MP0005257_abnormal_intraocular_pressure1.50036878
39MP0003787_abnormal_imprinting1.50018933
40MP0004885_abnormal_endolymph1.45972963
41MP0003119_abnormal_digestive_system1.44584805
42MP0002152_abnormal_brain_morphology1.44535609
43MP0001188_hyperpigmentation1.44179235
44MP0009780_abnormal_chondrocyte_physiolo1.42328773
45MP0001970_abnormal_pain_threshold1.39776425
46MP0001529_abnormal_vocalization1.37463896
47MP0001293_anophthalmia1.35869834
48MP0005645_abnormal_hypothalamus_physiol1.34667231
49MP0001485_abnormal_pinna_reflex1.33782752
50MP0002735_abnormal_chemical_nociception1.33610444
51MP0003329_amyloid_beta_deposits1.32696824
52MP0003123_paternal_imprinting1.29364153
53MP0003861_abnormal_nervous_system1.29214893
54MP0002066_abnormal_motor_capabilities/c1.26877214
55MP0002249_abnormal_larynx_morphology1.26201340
56MP0005248_abnormal_Harderian_gland1.26110688
57MP0000751_myopathy1.25726133
58MP0002234_abnormal_pharynx_morphology1.25331099
59MP0003121_genomic_imprinting1.24685482
60MP0005386_behavior/neurological_phenoty1.24118509
61MP0004924_abnormal_behavior1.24118509
62MP0003938_abnormal_ear_development1.18175286
63MP0008569_lethality_at_weaning1.16078700
64MP0000631_abnormal_neuroendocrine_gland1.14286771
65MP0005171_absent_coat_pigmentation1.11440893
66MP0000537_abnormal_urethra_morphology1.11076114
67MP0004142_abnormal_muscle_tone1.07395749
68MP0001286_abnormal_eye_development1.06939255
69MP0001501_abnormal_sleep_pattern1.05811131
70MP0001348_abnormal_lacrimal_gland1.02079073
71MP0003890_abnormal_embryonic-extraembry1.01727848
72MP0002653_abnormal_ependyma_morphology1.01197805
73MP0005551_abnormal_eye_electrophysiolog1.01021993
74MP0002938_white_spotting1.00290766
75MP0002233_abnormal_nose_morphology1.00264458
76MP0000428_abnormal_craniofacial_morphol0.98432928
77MP0003878_abnormal_ear_physiology0.98402138
78MP0005377_hearing/vestibular/ear_phenot0.98402138
79MP0002752_abnormal_somatic_nervous0.97821589
80MP0000049_abnormal_middle_ear0.97760440
81MP0005195_abnormal_posterior_eye0.96413564
82MP0002638_abnormal_pupillary_reflex0.95897660
83MP0003937_abnormal_limbs/digits/tail_de0.93916155
84MP0004742_abnormal_vestibular_system0.92867418
85MP0005394_taste/olfaction_phenotype0.92564041
86MP0005499_abnormal_olfactory_system0.92564041
87MP0002697_abnormal_eye_size0.92302510
88MP0003385_abnormal_body_wall0.91680454
89MP0001502_abnormal_circadian_rhythm0.91303427
90MP0008961_abnormal_basal_metabolism0.90702719
91MP0002822_catalepsy0.90599587
92MP0004233_abnormal_muscle_weight0.90186187
93MP0002069_abnormal_eating/drinking_beha0.89949726
94MP0003879_abnormal_hair_cell0.88470837
95MP0005379_endocrine/exocrine_gland_phen0.88338871
96MP0002751_abnormal_autonomic_nervous0.88281969
97MP0003942_abnormal_urinary_system0.87022697
98MP0002089_abnormal_postnatal_growth/wei0.86585600
99MP0001299_abnormal_eye_distance/0.85927607
100MP0002081_perinatal_lethality0.85122860
101MP0005167_abnormal_blood-brain_barrier0.84436725
102MP0009250_abnormal_appendicular_skeleto0.83552219
103MP0000462_abnormal_digestive_system0.83127381
104MP0006072_abnormal_retinal_apoptosis0.83106846
105MP0002160_abnormal_reproductive_system0.81868839
106MP0003633_abnormal_nervous_system0.78789079
107MP0000534_abnormal_ureter_morphology0.78560859
108MP0004134_abnormal_chest_morphology0.78356948
109MP0000538_abnormal_urinary_bladder0.78298726
110MP0002282_abnormal_trachea_morphology0.75028418
111MP0003755_abnormal_palate_morphology0.74782859
112MP0000026_abnormal_inner_ear0.72940409
113MP0004130_abnormal_muscle_cell0.72456335
114MP0010234_abnormal_vibrissa_follicle0.70987094
115MP0002116_abnormal_craniofacial_bone0.69416129
116MP0008789_abnormal_olfactory_epithelium0.68685642
117MP0003690_abnormal_glial_cell0.68251093
118MP0001905_abnormal_dopamine_level0.68243762
119MP0004043_abnormal_pH_regulation0.68240150
120MP0005187_abnormal_penis_morphology0.67235512
121MP0009672_abnormal_birth_weight0.67145354
122MP0001177_atelectasis0.67114366
123MP0004133_heterotaxia0.66840737
124MP0003634_abnormal_glial_cell0.66751587
125MP0001963_abnormal_hearing_physiology0.66008419
126MP0000569_abnormal_digit_pigmentation0.65947885
127MP0002837_dystrophic_cardiac_calcinosis0.65141321
128MP0002102_abnormal_ear_morphology0.64920453
129MP0001943_abnormal_respiration0.63921521

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.03240259
2Focal motor seizures (HP:0011153)4.69170498
3Ankle clonus (HP:0011448)4.20571276
4Impaired vibration sensation in the lower limbs (HP:0002166)4.18319878
5Spastic gait (HP:0002064)4.11352982
6Neoplasm of the heart (HP:0100544)4.01157222
7Urinary bladder sphincter dysfunction (HP:0002839)4.00896169
8Visual hallucinations (HP:0002367)3.71846084
9Reticulocytopenia (HP:0001896)3.67413298
10Lymphangioma (HP:0100764)3.54020681
11Urinary urgency (HP:0000012)3.43303027
12Focal seizures (HP:0007359)3.41103256
13Partial duplication of thumb phalanx (HP:0009944)3.34620156
14Supranuclear gaze palsy (HP:0000605)3.27100321
15Hyperacusis (HP:0010780)3.17010509
16Genetic anticipation (HP:0003743)3.10400971
17Insidious onset (HP:0003587)3.08978879
18Termporal pattern (HP:0011008)3.08978879
19Insomnia (HP:0100785)3.07153588
20Agitation (HP:0000713)2.97236059
21Partial duplication of the phalanx of hand (HP:0009999)2.96528343
22Polyphagia (HP:0002591)2.88433323
23Single umbilical artery (HP:0001195)2.86608499
24Abnormality of the fetal cardiovascular system (HP:0010948)2.86608499
25Abnormal umbilical cord blood vessels (HP:0011403)2.86608499
26Narrow nasal bridge (HP:0000446)2.84418228
27Shawl scrotum (HP:0000049)2.83634490
28Excessive salivation (HP:0003781)2.79877150
29Drooling (HP:0002307)2.79877150
30Septo-optic dysplasia (HP:0100842)2.78509335
31Coronal craniosynostosis (HP:0004440)2.77516574
32Abnormality of the corticospinal tract (HP:0002492)2.76499309
33Ependymoma (HP:0002888)2.73219483
34Renal duplication (HP:0000075)2.70879240
35Elfin facies (HP:0004428)2.69562975
36Epileptic encephalopathy (HP:0200134)2.69101150
37Rib fusion (HP:0000902)2.67873025
38Abnormality of the astrocytes (HP:0100707)2.62096328
39Astrocytoma (HP:0009592)2.62096328
40Broad-based gait (HP:0002136)2.61183529
41Progressive cerebellar ataxia (HP:0002073)2.60153242
42Abnormality of the phalanges of the hallux (HP:0010057)2.58035445
43Hemiparesis (HP:0001269)2.58002700
44Gait imbalance (HP:0002141)2.57487646
45Abnormality of the aortic arch (HP:0012303)2.57310160
46Mutism (HP:0002300)2.55507979
47Failure to thrive in infancy (HP:0001531)2.53983844
48Abnormality of cells of the erythroid lineage (HP:0012130)2.53621295
49Turricephaly (HP:0000262)2.51576213
50Abnormal eating behavior (HP:0100738)2.51084138
51Renovascular hypertension (HP:0100817)2.51049811
52Submucous cleft hard palate (HP:0000176)2.49398626
53Optic nerve hypoplasia (HP:0000609)2.46866405
54Action tremor (HP:0002345)2.46719737
55High anterior hairline (HP:0009890)2.46538135
56Abnormal pancreas size (HP:0012094)2.42980960
57Overriding aorta (HP:0002623)2.41936599
58Abnormal number of incisors (HP:0011064)2.39770275
59Shallow orbits (HP:0000586)2.37567346
60Febrile seizures (HP:0002373)2.36269330
61Atelectasis (HP:0100750)2.34547815
62Limb dystonia (HP:0002451)2.32062377
63Hyperthyroidism (HP:0000836)2.30709959
64Cerebral inclusion bodies (HP:0100314)2.29294482
65Apathy (HP:0000741)2.29064399
66Generalized tonic-clonic seizures (HP:0002069)2.27118696
67Maternal diabetes (HP:0009800)2.25736082
68Neonatal respiratory distress (HP:0002643)2.24259514
69Depression (HP:0000716)2.23969279
70Hamartoma of the eye (HP:0010568)2.22899734
71Lower limb muscle weakness (HP:0007340)2.22765394
72Long toe (HP:0010511)2.18507182
73Amblyopia (HP:0000646)2.18437481
74Neurofibrillary tangles (HP:0002185)2.18186452
75Hypoventilation (HP:0002791)2.17046935
76Duplication of thumb phalanx (HP:0009942)2.16722996
77Abnormality of the labia minora (HP:0012880)2.15616888
78Amyotrophic lateral sclerosis (HP:0007354)2.14564343
79Impaired vibratory sensation (HP:0002495)2.14259044
80Broad alveolar ridges (HP:0000187)2.10603670
81Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.10449210
82Flat cornea (HP:0007720)2.08611707
83Akinesia (HP:0002304)2.07284043
84Torticollis (HP:0000473)2.06413100
85Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.05862960
86Atonic seizures (HP:0010819)2.04568139
87Hypoplasia of the brainstem (HP:0002365)2.04443714
88Aplasia/Hypoplasia of the brainstem (HP:0007362)2.04443714
89Ventricular fibrillation (HP:0001663)2.04369224
90Abnormality of the nasal septum (HP:0000419)2.04139449
91Diminished motivation (HP:0000745)2.03327391
92Nephrogenic diabetes insipidus (HP:0009806)2.02899107
93Neoplasm of the adrenal cortex (HP:0100641)2.01532629
94Focal dystonia (HP:0004373)2.01201368
95Abnormality of binocular vision (HP:0011514)2.00178558
96Diplopia (HP:0000651)2.00178558
97Congenital primary aphakia (HP:0007707)1.99328155
98Degeneration of the lateral corticospinal tracts (HP:0002314)1.98966565
99Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.98966565
100Shoulder girdle muscle weakness (HP:0003547)1.98377530
101Absence seizures (HP:0002121)1.97885644
102Abnormality of the lower motor neuron (HP:0002366)1.95235440
103Pointed chin (HP:0000307)1.94673387
104Hyperglycinemia (HP:0002154)1.93908948
105Thoracolumbar scoliosis (HP:0002944)1.93432891
106Enlarged penis (HP:0000040)1.92983878
107Clonus (HP:0002169)1.91553366
108Craniofacial dystonia (HP:0012179)1.89457078
109Medial flaring of the eyebrow (HP:0010747)1.88370012
110Abnormality of midbrain morphology (HP:0002418)1.87815106
111Molar tooth sign on MRI (HP:0002419)1.87815106
112Stereotypic behavior (HP:0000733)1.87274419
113Sporadic (HP:0003745)1.86621119
114Anxiety (HP:0000739)1.86493309
115Vaginal atresia (HP:0000148)1.85769830
116Megalencephaly (HP:0001355)1.85184457
117Anophthalmia (HP:0000528)1.84584334
118Oligodactyly (hands) (HP:0001180)1.83106027
119Chronic hepatic failure (HP:0100626)1.83014732
120Poor coordination (HP:0002370)1.82761611
121Epidermoid cyst (HP:0200040)1.82636401
122Hepatoblastoma (HP:0002884)1.81365061
123Papilledema (HP:0001085)1.81193407
124Renal dysplasia (HP:0000110)1.79833147
125Abnormality of the diencephalon (HP:0010662)1.79803119
126Ulnar claw (HP:0001178)1.79232394
127Morphological abnormality of the pyramidal tract (HP:0002062)1.78883606
128Deep palmar crease (HP:0006191)1.78668330
129Bowel diverticulosis (HP:0005222)1.78410753
130Precocious puberty (HP:0000826)1.77945220
131Specific learning disability (HP:0001328)1.77840940
132Short 4th metacarpal (HP:0010044)1.77240735
133Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.77240735
134Broad metatarsal (HP:0001783)1.76854111
135Back pain (HP:0003418)1.75957713
136Intellectual disability, severe (HP:0010864)1.75573213
137Genital tract atresia (HP:0001827)1.75421039
138Hypsarrhythmia (HP:0002521)1.75073777
139Increased IgM level (HP:0003496)1.74894145
140Paraplegia (HP:0010550)1.74673205
141Pachygyria (HP:0001302)1.74489554
142Retinal dysplasia (HP:0007973)1.73426268
143Type II lissencephaly (HP:0007260)1.73263929
144Abnormal number of erythroid precursors (HP:0012131)1.73257421
145Oligodactyly (HP:0012165)1.69905344
146Spastic tetraplegia (HP:0002510)1.68959637
147Hypercalciuria (HP:0002150)1.65008147
148Megalocornea (HP:0000485)1.64938065
149Facial hemangioma (HP:0000329)1.63631874
150Absent septum pellucidum (HP:0001331)1.62071233
151Status epilepticus (HP:0002133)1.61574758
152Midline defect of the nose (HP:0004122)1.60673012
153Lissencephaly (HP:0001339)1.60079530
154Abnormality of the 4th metacarpal (HP:0010012)1.57392469
155Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.54373373
156Esotropia (HP:0000565)1.54244542
157Buphthalmos (HP:0000557)1.53404220
158Diastasis recti (HP:0001540)1.52583863
159Patellar aplasia (HP:0006443)1.51935903
160Nephronophthisis (HP:0000090)1.51933118
161Vaginal fistula (HP:0004320)1.51709531
162Trigonocephaly (HP:0000243)1.51557070
163Anterior segment dysgenesis (HP:0007700)1.50603981
164Preaxial foot polydactyly (HP:0001841)1.49439842
165Adrenal hypoplasia (HP:0000835)1.48278791
166Hyperglycinuria (HP:0003108)1.48107964
167Impulsivity (HP:0100710)1.47816965
168Rectal fistula (HP:0100590)1.47672654
169Rectovaginal fistula (HP:0000143)1.47672654
170Hypoplasia of the corpus callosum (HP:0002079)1.47354260
171Micropenis (HP:0000054)1.47206428
172Anosmia (HP:0000458)1.47114962
173Prominent supraorbital ridges (HP:0000336)1.46381822
174Spina bifida occulta (HP:0003298)1.45281234
175Broad foot (HP:0001769)1.44319539

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.56842389
2NTRK32.03452295
3INSRR11.6901914
4MAP3K91.99407104
5TRIM281.98757726
6DYRK1B1.95226452
7PRKD21.93316767
8EPHA41.84667869
9LIMK11.84295212
10MARK21.83789396
11KSR21.68391179
12KSR11.67864780
13MAP3K41.61120385
14MAP3K71.49615286
15WNK41.48826710
16MINK11.48655810
17PKN11.46734589
18PINK11.46137239
19PAK61.36545282
20NTRK21.30190486
21MAPK131.29859639
22BCKDK1.29435932
23DAPK21.29058439
24SIK21.26102951
25STK161.20807078
26DYRK21.19137512
27TRIB31.18289117
28SIK11.17196347
29EPHB21.16918797
30PHKG21.16046923
31PHKG11.16046923
32UHMK11.13816219
33PKN21.13679647
34EPHA21.11200441
35LATS21.07665987
36MAP2K71.04496498
37FGFR21.03500359
38TYRO31.03204770
39MAP3K21.01404377
40CAMK40.99524876
41PRKD30.99453949
42CAMKK10.94477458
43CDK50.92645281
44CAMK10.91580276
45MAP3K110.90654858
46BCR0.90285881
47ZAK0.86805278
48TLK10.83225902
49CSNK1G30.81668282
50DAPK10.81066459
51RPS6KA20.81050519
52CDC42BPA0.80500583
53CDK190.80383652
54PAK30.79815109
55MUSK0.76612638
56ERBB20.75579947
57CASK0.74373536
58STK110.74169242
59NTRK10.73205583
60TAOK10.72883055
61DDR20.72061225
62CSNK1A1L0.72016962
63CDK140.69984319
64CDK180.69281038
65CAMK1D0.68840998
66PDGFRA0.68482972
67CDK150.68325988
68RET0.66410039
69ICK0.66317664
70PLK20.65997831
71PNCK0.65234661
72IRAK20.64770130
73PRKCZ0.64269161
74ERBB30.64028421
75PRKCG0.63839127
76CSNK1G10.63758852
77ALK0.63338915
78MAP2K40.62594130
79DYRK30.61477821
80CDK11A0.59486681
81AURKA0.59066593
82RPS6KA60.56856441
83EEF2K0.56818044
84PRKCI0.53679869
85DYRK1A0.52072326
86GRK50.51980803
87MAPK150.51597295
88FER0.50862525
89PRKCH0.49460479
90LMTK20.49320151
91PRKAA10.49315683
92PTK20.49068689
93CSNK1E0.48422005
94NEK20.47736082
95LRRK20.46579653
96SCYL20.45385206
97MTOR0.44965133
98NME10.43409539
99PRKACA0.41191750
100STK30.40789660
101DMPK0.40518358
102PRKD10.40429308
103CHEK20.38589517
104ADRBK20.38275302
105CSNK1D0.37547856
106ABL20.37170971
107STK380.36665260
108WNK30.36463694
109SIK30.36059652
110ARAF0.36032418
111ADRBK10.35955306
112FES0.35864764
113PRKAA20.35799907
114DAPK30.35675043
115MAP2K20.35045461
116CAMK2A0.34337495
117CSNK1G20.33096925
118IRAK10.31573941
119MAPK90.28195190
120MAP2K10.28002044
121CAMK2B0.27837269
122TNIK0.27773674
123ROCK20.27093814
124OXSR10.24995689
125BRAF0.24068093
126MAP3K120.23829776
127MAP3K10.23784379
128PDPK10.22953175
129MAPK120.22234268
130RPS6KL10.21725892
131RPS6KC10.21725892
132CAMK1G0.21481700
133SGK10.20807719
134SGK4940.20216082
135SGK2230.20216082

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.07120370
2Nicotine addiction_Homo sapiens_hsa050332.83043798
3Sulfur relay system_Homo sapiens_hsa041222.54596875
4Glutamatergic synapse_Homo sapiens_hsa047242.49355181
5GABAergic synapse_Homo sapiens_hsa047272.40592976
6Olfactory transduction_Homo sapiens_hsa047402.39175780
7Circadian entrainment_Homo sapiens_hsa047132.33713993
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.31395589
9Long-term potentiation_Homo sapiens_hsa047202.22290968
10Axon guidance_Homo sapiens_hsa043602.16093487
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.10948995
12Morphine addiction_Homo sapiens_hsa050322.07868957
13Ribosome_Homo sapiens_hsa030101.94502586
14Dopaminergic synapse_Homo sapiens_hsa047281.94474625
15Amphetamine addiction_Homo sapiens_hsa050311.93580781
16Insulin secretion_Homo sapiens_hsa049111.84035272
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.83455555
18Gap junction_Homo sapiens_hsa045401.78714559
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.78444676
20Cholinergic synapse_Homo sapiens_hsa047251.78338431
21Oxytocin signaling pathway_Homo sapiens_hsa049211.74133464
22Cocaine addiction_Homo sapiens_hsa050301.68327572
23Gastric acid secretion_Homo sapiens_hsa049711.63258602
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.59691386
25Long-term depression_Homo sapiens_hsa047301.56050414
26Salivary secretion_Homo sapiens_hsa049701.54047795
27Taste transduction_Homo sapiens_hsa047421.52361947
28GnRH signaling pathway_Homo sapiens_hsa049121.52234911
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.50272650
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.45283104
31Type II diabetes mellitus_Homo sapiens_hsa049301.45027831
32Steroid biosynthesis_Homo sapiens_hsa001001.42728191
33Glioma_Homo sapiens_hsa052141.36407894
34Serotonergic synapse_Homo sapiens_hsa047261.35179062
35Melanogenesis_Homo sapiens_hsa049161.34310610
36Renin secretion_Homo sapiens_hsa049241.32398969
37Estrogen signaling pathway_Homo sapiens_hsa049151.28768275
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.27264149
39mTOR signaling pathway_Homo sapiens_hsa041501.22227705
40Oxidative phosphorylation_Homo sapiens_hsa001901.20515232
41Cardiac muscle contraction_Homo sapiens_hsa042601.20387771
42ErbB signaling pathway_Homo sapiens_hsa040121.20186368
43Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.17847639
44Hedgehog signaling pathway_Homo sapiens_hsa043401.16511723
45Collecting duct acid secretion_Homo sapiens_hsa049661.15464574
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.14171566
47Parkinsons disease_Homo sapiens_hsa050121.09398793
48Arginine and proline metabolism_Homo sapiens_hsa003301.06015121
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.05146306
50Notch signaling pathway_Homo sapiens_hsa043301.03675318
51cAMP signaling pathway_Homo sapiens_hsa040241.03062790
52Endometrial cancer_Homo sapiens_hsa052131.02162565
53Vitamin B6 metabolism_Homo sapiens_hsa007501.01420426
54Calcium signaling pathway_Homo sapiens_hsa040200.99802461
55Alcoholism_Homo sapiens_hsa050340.95081052
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.94996782
57Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91735354
58Prion diseases_Homo sapiens_hsa050200.91239892
59Dilated cardiomyopathy_Homo sapiens_hsa054140.90550715
60Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89257770
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.88146019
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.88058065
63Huntingtons disease_Homo sapiens_hsa050160.87767045
64Vibrio cholerae infection_Homo sapiens_hsa051100.87160921
65Choline metabolism in cancer_Homo sapiens_hsa052310.86636115
66Alzheimers disease_Homo sapiens_hsa050100.85801393
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.85639987
68AMPK signaling pathway_Homo sapiens_hsa041520.84851591
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84836480
70Insulin signaling pathway_Homo sapiens_hsa049100.84705778
71Longevity regulating pathway - mammal_Homo sapiens_hsa042110.81947282
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.80719524
73Oocyte meiosis_Homo sapiens_hsa041140.80268260
74Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.79394263
75Basal cell carcinoma_Homo sapiens_hsa052170.78783868
76MAPK signaling pathway_Homo sapiens_hsa040100.78539740
77Wnt signaling pathway_Homo sapiens_hsa043100.78152548
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77213127
79VEGF signaling pathway_Homo sapiens_hsa043700.76283934
80Phototransduction_Homo sapiens_hsa047440.73603704
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.72869115
82Dorso-ventral axis formation_Homo sapiens_hsa043200.71679448
83Renal cell carcinoma_Homo sapiens_hsa052110.69219557
84Melanoma_Homo sapiens_hsa052180.68456694
85Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.67976085
86Colorectal cancer_Homo sapiens_hsa052100.67156407
87Non-small cell lung cancer_Homo sapiens_hsa052230.66907433
88Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65131562
89Hippo signaling pathway_Homo sapiens_hsa043900.64888362
90Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64792142
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64465036
92Ras signaling pathway_Homo sapiens_hsa040140.64256765
93Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64234465
94Peroxisome_Homo sapiens_hsa041460.63214753
95Rap1 signaling pathway_Homo sapiens_hsa040150.62475908
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.61859256
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61794710
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61039806
99Bladder cancer_Homo sapiens_hsa052190.58428024
100Prostate cancer_Homo sapiens_hsa052150.58034236
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57537922
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56875846
103Butanoate metabolism_Homo sapiens_hsa006500.56595023
104Ovarian steroidogenesis_Homo sapiens_hsa049130.55945877
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54924526
106Central carbon metabolism in cancer_Homo sapiens_hsa052300.54534654
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54036294
108Glucagon signaling pathway_Homo sapiens_hsa049220.53312553
109Thyroid hormone synthesis_Homo sapiens_hsa049180.51515471
110Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51089276
111Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.50826728
112Bile secretion_Homo sapiens_hsa049760.50194607
113Basal transcription factors_Homo sapiens_hsa030220.49806094
114Nitrogen metabolism_Homo sapiens_hsa009100.49554381
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.49237584
116Proteoglycans in cancer_Homo sapiens_hsa052050.49113195
117Pancreatic secretion_Homo sapiens_hsa049720.48393201
118Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47469434
119Tight junction_Homo sapiens_hsa045300.46296822
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45909266
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44958144
122Maturity onset diabetes of the young_Homo sapiens_hsa049500.43586810
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.40721195
124Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40697215
125Biosynthesis of amino acids_Homo sapiens_hsa012300.40211208
126Sphingolipid signaling pathway_Homo sapiens_hsa040710.39744716
127Folate biosynthesis_Homo sapiens_hsa007900.38679194
128Phenylalanine metabolism_Homo sapiens_hsa003600.37751296
1292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.36456960
130Pyruvate metabolism_Homo sapiens_hsa006200.35416972

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