VRTN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell migration involved in gastrulation (GO:0042074)5.81559022
2mitotic metaphase plate congression (GO:0007080)5.21739457
3L-serine metabolic process (GO:0006563)5.20550571
4regulation of gene silencing by RNA (GO:0060966)4.97784433
5regulation of posttranscriptional gene silencing (GO:0060147)4.97784433
6regulation of gene silencing by miRNA (GO:0060964)4.97784433
7protein complex localization (GO:0031503)4.94944221
8positive regulation of SMAD protein import into nucleus (GO:0060391)4.87249132
9DNA unwinding involved in DNA replication (GO:0006268)4.58625358
10regulation of cell fate specification (GO:0042659)4.54081806
11base-excision repair, AP site formation (GO:0006285)4.52039951
12pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.51278148
13pre-miRNA processing (GO:0031054)4.44287372
14metaphase plate congression (GO:0051310)4.39986942
15establishment of integrated proviral latency (GO:0075713)4.35979837
16folic acid-containing compound biosynthetic process (GO:0009396)4.29693361
17regulation of helicase activity (GO:0051095)4.19119836
18ribosome assembly (GO:0042255)4.18017444
19protein localization to kinetochore (GO:0034501)4.16994705
20mitotic chromosome condensation (GO:0007076)4.15833804
21regulation of mesoderm development (GO:2000380)4.15509584
22protein K6-linked ubiquitination (GO:0085020)4.14101467
23signal transduction involved in regulation of gene expression (GO:0023019)4.13007822
24IMP biosynthetic process (GO:0006188)4.10714135
25paraxial mesoderm development (GO:0048339)4.07848300
26piRNA metabolic process (GO:0034587)4.06736309
27negative regulation of histone methylation (GO:0031061)4.02691357
28DNA replication initiation (GO:0006270)4.00156503
29nodal signaling pathway (GO:0038092)4.00049050
30L-alpha-amino acid transmembrane transport (GO:1902475)3.94665204
31establishment of chromosome localization (GO:0051303)3.89866373
32mitotic nuclear envelope disassembly (GO:0007077)3.88021662
33histone H2A monoubiquitination (GO:0035518)3.87514794
34DNA replication-dependent nucleosome assembly (GO:0006335)3.80052502
35DNA replication-dependent nucleosome organization (GO:0034723)3.80052502
36regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.77303205
37cell fate commitment involved in formation of primary germ layer (GO:0060795)3.73335358
38protein localization to chromosome, centromeric region (GO:0071459)3.71057623
39regulation of sister chromatid cohesion (GO:0007063)3.67197851
40pyrimidine nucleotide catabolic process (GO:0006244)3.65510376
41membrane disassembly (GO:0030397)3.63509754
42nuclear envelope disassembly (GO:0051081)3.63509754
43negative regulation of translation, ncRNA-mediated (GO:0040033)3.63354263
44regulation of translation, ncRNA-mediated (GO:0045974)3.63354263
45negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.63354263
46regulation of mitotic spindle checkpoint (GO:1903504)3.61160856
47regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.61160856
48DNA strand elongation involved in DNA replication (GO:0006271)3.60208259
49nuclear pore complex assembly (GO:0051292)3.59021995
50purine nucleobase biosynthetic process (GO:0009113)3.58887166
51mitotic sister chromatid segregation (GO:0000070)3.53078987
52regulation of chromatin silencing (GO:0031935)3.46775602
53somatic hypermutation of immunoglobulin genes (GO:0016446)3.45873014
54somatic diversification of immune receptors via somatic mutation (GO:0002566)3.45873014
55notochord development (GO:0030903)3.45223679
56CENP-A containing nucleosome assembly (GO:0034080)3.43280876
57attachment of spindle microtubules to kinetochore (GO:0008608)3.41114429
58regulation of SMAD protein import into nucleus (GO:0060390)3.40653776
59DNA strand elongation (GO:0022616)3.39259773
60histone H2A ubiquitination (GO:0033522)3.39158373
61cellular protein complex localization (GO:0034629)3.38831629
62ATP-dependent chromatin remodeling (GO:0043044)3.38536984
63negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.37525354
64regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.36195947
65regulation of histone H3-K9 methylation (GO:0051570)3.35816196
66chromatin remodeling at centromere (GO:0031055)3.35135515
67lung-associated mesenchyme development (GO:0060484)3.34179204
68regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.32578653
69DNA replication checkpoint (GO:0000076)3.29093225
70epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.28624659
71negative regulation of telomerase activity (GO:0051974)3.26370891
72histone exchange (GO:0043486)3.26276879
73negative regulation of chromosome segregation (GO:0051985)3.26261433
74DNA replication-independent nucleosome organization (GO:0034724)3.25767709
75DNA replication-independent nucleosome assembly (GO:0006336)3.25767709
76regulation of cell fate commitment (GO:0010453)3.23914956
77serine family amino acid biosynthetic process (GO:0009070)3.23766643
78negative regulation of mitotic sister chromatid separation (GO:2000816)3.22948045
79negative regulation of mitotic sister chromatid segregation (GO:0033048)3.22948045
80negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.22948045
81negative regulation of sister chromatid segregation (GO:0033046)3.22948045
82DNA damage response, detection of DNA damage (GO:0042769)3.22902278
83regulation of spindle organization (GO:0090224)3.22696593
84regulation of chromosome segregation (GO:0051983)3.21994320
85anterior/posterior axis specification, embryo (GO:0008595)3.21639378
86spindle checkpoint (GO:0031577)3.20766871
87spliceosomal snRNP assembly (GO:0000387)3.20710909
88ribosome biogenesis (GO:0042254)3.18423608
89telomere maintenance via semi-conservative replication (GO:0032201)3.18192957
90positive regulation of chromosome segregation (GO:0051984)3.18005066
91regulation of female gonad development (GO:2000194)3.17637364
92negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.17129528
93peptidyl-arginine omega-N-methylation (GO:0035247)3.15356553
94IMP metabolic process (GO:0046040)3.11651948
95nucleobase biosynthetic process (GO:0046112)3.10132306
96establishment of viral latency (GO:0019043)3.10090299
97regulation of nuclear cell cycle DNA replication (GO:0033262)3.09595713
98maturation of SSU-rRNA (GO:0030490)3.09055036
99protein localization to chromosome (GO:0034502)3.07598065
100peptidyl-arginine modification (GO:0018195)3.07520969
101regulation of mitotic metaphase/anaphase transition (GO:0030071)3.07257977
102mitotic spindle assembly checkpoint (GO:0007094)3.05995894
103regulation of sister chromatid segregation (GO:0033045)3.05532543
104regulation of mitotic sister chromatid separation (GO:0010965)3.05532543
105regulation of mitotic sister chromatid segregation (GO:0033047)3.05532543
106kinetochore assembly (GO:0051382)3.05056651
107mitotic spindle checkpoint (GO:0071174)3.02130632
108positive regulation of histone H3-K4 methylation (GO:0051571)3.02107810
109lysine metabolic process (GO:0006553)3.01951997
110lysine catabolic process (GO:0006554)3.01951997
111nuclear pore organization (GO:0006999)3.01945348
112primitive streak formation (GO:0090009)3.01642862
113negative regulation of DNA-dependent DNA replication (GO:2000104)3.01269416
114spindle assembly checkpoint (GO:0071173)3.00152746
115positive regulation of catenin import into nucleus (GO:0035413)2.99432139
116negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.99417001
117negative regulation of DNA-templated transcription, elongation (GO:0032785)2.99417001
118negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.99233935
119regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.99175487
120regulation of gene silencing (GO:0060968)2.98957507
121heterochromatin organization (GO:0070828)2.98719079
122rRNA modification (GO:0000154)2.97437861
123pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.96966189
124telomere maintenance via telomerase (GO:0007004)2.95380191
125regulation of telomere maintenance via telomerase (GO:0032210)2.94934101
126histone arginine methylation (GO:0034969)2.94013494
127sister chromatid segregation (GO:0000819)2.93991113
128negative regulation of smooth muscle cell differentiation (GO:0051151)2.93960327
129negative regulation of mitosis (GO:0045839)2.93873725
130chromatin assembly or disassembly (GO:0006333)2.93758276
131single strand break repair (GO:0000012)2.93549979
132otic vesicle formation (GO:0030916)2.93530472
133base-excision repair (GO:0006284)2.93433394
134proteasome assembly (GO:0043248)2.93267170
135negative regulation of androgen receptor signaling pathway (GO:0060766)2.93033881
136maturation of 5.8S rRNA (GO:0000460)2.91720667
137negative regulation of gene silencing (GO:0060969)2.91527806
138regulation of stem cell maintenance (GO:2000036)2.91220069
139chromatin assembly (GO:0031497)2.90361504
140gene silencing by RNA (GO:0031047)2.89866726
141kinetochore organization (GO:0051383)2.89704374
142non-recombinational repair (GO:0000726)2.89672262
143double-strand break repair via nonhomologous end joining (GO:0006303)2.89672262
144regulation of exit from mitosis (GO:0007096)2.88478176
145convergent extension (GO:0060026)2.86257664
146negative regulation of cell fate commitment (GO:0010454)2.83136408
147negative regulation of cell fate specification (GO:0009996)2.81435808
148ncRNA catabolic process (GO:0034661)2.80561535

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.79396899
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.94378318
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.61120581
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.76677914
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.51478545
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.23537840
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.16052280
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.98603679
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.92745179
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.86957888
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.78985214
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.63317516
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.52809470
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.49302735
15AR_21909140_ChIP-Seq_LNCAP_Human2.48056760
16XRN2_22483619_ChIP-Seq_HELA_Human2.42216049
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38827177
18MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.32453360
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.30399869
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.29780171
21NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.28198649
22POU5F1_16153702_ChIP-ChIP_HESCs_Human2.27218829
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.18907413
24TP63_19390658_ChIP-ChIP_HaCaT_Human2.18629996
25E2F1_21310950_ChIP-Seq_MCF-7_Human2.13418530
26MYCN_18555785_ChIP-Seq_MESCs_Mouse2.12543105
27NANOG_18555785_ChIP-Seq_MESCs_Mouse2.02825770
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.02115964
29POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.00032524
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.96618777
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.95169941
32TTF2_22483619_ChIP-Seq_HELA_Human1.90758198
33GABP_19822575_ChIP-Seq_HepG2_Human1.88095165
34NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.86137148
35MYC_18940864_ChIP-ChIP_HL60_Human1.79295553
36KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.78132695
37ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.75386269
38POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.73962541
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.73285312
40VDR_23849224_ChIP-Seq_CD4+_Human1.72269801
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.70999136
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67650904
43TCF3_18692474_ChIP-Seq_MEFs_Mouse1.67257399
44CIITA_25753668_ChIP-Seq_RAJI_Human1.62068318
45FOXP3_21729870_ChIP-Seq_TREG_Human1.61784500
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.59903252
47DCP1A_22483619_ChIP-Seq_HELA_Human1.59483356
48E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.59053658
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.57003579
50KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.55446438
51KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.55446438
52KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.55446438
53CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.52264775
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.51347898
55KDM5A_27292631_Chip-Seq_BREAST_Human1.50810998
56CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.50434524
57HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.48984862
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45590543
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45423843
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.44529467
61MYC_22102868_ChIP-Seq_BL_Human1.37450138
62NANOG_21062744_ChIP-ChIP_HESCs_Human1.37437749
63TCF3_18692474_ChIP-Seq_MESCs_Mouse1.35641219
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.34927083
65KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29454931
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.26397030
67E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25515312
68ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.22023234
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.20952948
70CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.19385031
71SALL1_21062744_ChIP-ChIP_HESCs_Human1.17496520
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.16490816
73CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.14889351
74SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.14672392
75TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.14469318
76POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.13628362
77SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09577422
78ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.07638147
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06871978
80RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.04854328
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04846944
82NANOG_18692474_ChIP-Seq_MEFs_Mouse1.04076844
83DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03290885
84NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.01729560
85SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01646702
86ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00046397
87PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.00041319
88NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.99638348
89RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98525830
90HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.98041165
91KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96988548
92TFEB_21752829_ChIP-Seq_HELA_Human0.96808598
93NANOG_16153702_ChIP-ChIP_HESCs_Human0.96071500
94SOX17_20123909_ChIP-Seq_XEN_Mouse0.95133287
95POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.94809657
96POU5F1_16518401_ChIP-PET_MESCs_Mouse0.94638198
97NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.93943494
98EWS_26573619_Chip-Seq_HEK293_Human0.93752510
99NANOG_18692474_ChIP-Seq_MESCs_Mouse0.92854206
100FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.91885772
101TBX3_20139965_ChIP-Seq_ESCs_Mouse0.91068788
102ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90594138
103OCT4_18692474_ChIP-Seq_MEFs_Mouse0.90592877
104SOX2_18692474_ChIP-Seq_MEFs_Mouse0.90561858
105SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90424076
106CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89338445
107RBPJ_22232070_ChIP-Seq_NCS_Mouse0.87676833
108SRF_21415370_ChIP-Seq_HL-1_Mouse0.87629787
109ELK1_19687146_ChIP-ChIP_HELA_Human0.84855087
110TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.82675091
111STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82272820
112GATA1_26923725_Chip-Seq_HPCs_Mouse0.82093110
113TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.82047743
114ATF3_27146783_Chip-Seq_COLON_Human0.81956741
115SOX2_16153702_ChIP-ChIP_HESCs_Human0.81757090
116PADI4_21655091_ChIP-ChIP_MCF-7_Human0.81492701
117SOX2_18692474_ChIP-Seq_MESCs_Mouse0.80812931

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.71535718
2MP0003890_abnormal_embryonic-extraembry4.65157187
3MP0008877_abnormal_DNA_methylation4.27606319
4MP0003941_abnormal_skin_development4.23814888
5MP0004957_abnormal_blastocyst_morpholog4.14573777
6MP0003111_abnormal_nucleus_morphology3.68610584
7MP0003077_abnormal_cell_cycle3.64277051
8MP0010094_abnormal_chromosome_stability3.49092239
9MP0003718_maternal_effect3.42383134
10MP0003123_paternal_imprinting3.01769373
11MP0008932_abnormal_embryonic_tissue2.88766734
12MP0001730_embryonic_growth_arrest2.73415591
13MP0003646_muscle_fatigue2.55917208
14MP0002653_abnormal_ependyma_morphology2.55551667
15MP0010030_abnormal_orbit_morphology2.50205008
16MP0004133_heterotaxia2.47162927
17MP0003315_abnormal_perineum_morphology2.39515006
18MP0003119_abnormal_digestive_system2.38700183
19MP0003136_yellow_coat_color2.34404405
20MP0006292_abnormal_olfactory_placode2.31051022
21MP0005380_embryogenesis_phenotype2.15711925
22MP0001672_abnormal_embryogenesis/_devel2.15711925
23MP0002084_abnormal_developmental_patter2.10073990
24MP0008058_abnormal_DNA_repair2.07652622
25MP0000350_abnormal_cell_proliferation2.05981748
26MP0003937_abnormal_limbs/digits/tail_de2.04743603
27MP0002085_abnormal_embryonic_tissue2.03098970
28MP0008057_abnormal_DNA_replication1.97521574
29MP0001697_abnormal_embryo_size1.93709559
30MP0008007_abnormal_cellular_replicative1.83066222
31MP0003121_genomic_imprinting1.78477104
32MP0003984_embryonic_growth_retardation1.69539132
33MP0001188_hyperpigmentation1.68728560
34MP0002088_abnormal_embryonic_growth/wei1.66508883
35MP0002697_abnormal_eye_size1.65910401
36MP0000678_abnormal_parathyroid_gland1.65578755
37MP0002102_abnormal_ear_morphology1.64567525
38MP0010352_gastrointestinal_tract_polyps1.53280969
39MP0002080_prenatal_lethality1.49753326
40MP0002234_abnormal_pharynx_morphology1.49602991
41MP0005451_abnormal_body_composition1.45451282
42MP0003878_abnormal_ear_physiology1.44960769
43MP0005377_hearing/vestibular/ear_phenot1.44960769
44MP0002210_abnormal_sex_determination1.41345201
45MP0001119_abnormal_female_reproductive1.37481081
46MP0002160_abnormal_reproductive_system1.37173435
47MP0000537_abnormal_urethra_morphology1.34168928
48MP0002086_abnormal_extraembryonic_tissu1.33345363
49MP0009672_abnormal_birth_weight1.32317552
50MP0001929_abnormal_gametogenesis1.29609814
51MP0000653_abnormal_sex_gland1.28936307
52MP0003699_abnormal_female_reproductive1.28495799
53MP0005187_abnormal_penis_morphology1.27092168
54MP0001299_abnormal_eye_distance/1.21691387
55MP0002111_abnormal_tail_morphology1.21534219
56MP0002249_abnormal_larynx_morphology1.20970484
57MP0005395_other_phenotype1.18538629
58MP0003787_abnormal_imprinting1.16100220
59MP0000432_abnormal_head_morphology1.14197955
60MP0002796_impaired_skin_barrier1.14120715
61MP0002938_white_spotting1.12849713
62MP0001293_anophthalmia1.10596199
63MP0004197_abnormal_fetal_growth/weight/1.09097585
64MP0003861_abnormal_nervous_system1.08941436
65MP0001145_abnormal_male_reproductive1.08750588
66MP0003942_abnormal_urinary_system1.07033401
67MP0000428_abnormal_craniofacial_morphol1.06363929
68MP0006072_abnormal_retinal_apoptosis1.05457116
69MP0003935_abnormal_craniofacial_develop1.04522746
70MP0005389_reproductive_system_phenotype1.03072124
71MP0000049_abnormal_middle_ear1.01543508
72MP0000313_abnormal_cell_death1.01440898
73MP0001485_abnormal_pinna_reflex1.00292589
74MP0009053_abnormal_anal_canal1.00028901
75MP0003806_abnormal_nucleotide_metabolis0.97019731
76MP0009697_abnormal_copulation0.96686588
77MP0002019_abnormal_tumor_incidence0.96459083
78MP0005257_abnormal_intraocular_pressure0.96241168
79MP0009379_abnormal_foot_pigmentation0.94885004
80MP0001849_ear_inflammation0.92495911
81MP0006035_abnormal_mitochondrial_morpho0.92360182
82MP0002254_reproductive_system_inflammat0.90799890
83MP0001727_abnormal_embryo_implantation0.86741622
84MP0002932_abnormal_joint_morphology0.85785170
85MP0004185_abnormal_adipocyte_glucose0.85739295
86MP0003122_maternal_imprinting0.85731236
87MP0001286_abnormal_eye_development0.84797114
88MP0001529_abnormal_vocalization0.84368481
89MP0008789_abnormal_olfactory_epithelium0.83228250
90MP0002751_abnormal_autonomic_nervous0.82286915
91MP0004272_abnormal_basement_membrane0.80907335
92MP0002736_abnormal_nociception_after0.78853465
93MP0001915_intracranial_hemorrhage0.78775342
94MP0002161_abnormal_fertility/fecundity0.78469785
95MP0003938_abnormal_ear_development0.78140585
96MP0002127_abnormal_cardiovascular_syste0.77600495
97MP0000490_abnormal_crypts_of0.77507204
98MP0002116_abnormal_craniofacial_bone0.76033950
99MP0010307_abnormal_tumor_latency0.75973530
100MP0001177_atelectasis0.74580608
101MP0003755_abnormal_palate_morphology0.74068882
102MP0003186_abnormal_redox_activity0.73806269
103MP0005394_taste/olfaction_phenotype0.73715572
104MP0005499_abnormal_olfactory_system0.73715572
105MP0002090_abnormal_vision0.73709468
106MP0003786_premature_aging0.73530073
107MP0002332_abnormal_exercise_endurance0.69959284
108MP0002092_abnormal_eye_morphology0.68713274
109MP0003567_abnormal_fetal_cardiomyocyte0.68340904
110MP0000579_abnormal_nail_morphology0.67704549
111MP0009703_decreased_birth_body0.67197189
112MP0002925_abnormal_cardiovascular_devel0.66940784
113MP0003705_abnormal_hypodermis_morpholog0.64959951
114MP0008770_decreased_survivor_rate0.64299533
115MP0002233_abnormal_nose_morphology0.63598112
116MP0001919_abnormal_reproductive_system0.63492917
117MP0003115_abnormal_respiratory_system0.63100826
118MP0005501_abnormal_skin_physiology0.62686062
119MP0000566_synostosis0.61662597
120MP0004264_abnormal_extraembryonic_tissu0.61503359
121MP0002081_perinatal_lethality0.61199825
122MP0005384_cellular_phenotype0.61126511
123MP0000762_abnormal_tongue_morphology0.60979305
124MP0000462_abnormal_digestive_system0.59688517
125MP0000647_abnormal_sebaceous_gland0.59174594
126MP0009278_abnormal_bone_marrow0.58816682
127MP0003283_abnormal_digestive_organ0.58086438
128MP0002177_abnormal_outer_ear0.58081565
129MP0000631_abnormal_neuroendocrine_gland0.57354655
130MP0005621_abnormal_cell_physiology0.57317384
131MP0002089_abnormal_postnatal_growth/wei0.57308766
132MP0002114_abnormal_axial_skeleton0.56214513
133MP0000266_abnormal_heart_morphology0.55985804
134MP0004233_abnormal_muscle_weight0.54971551
135MP0001661_extended_life_span0.54097499

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.59900991
2Breast hypoplasia (HP:0003187)4.21234064
3Colon cancer (HP:0003003)3.92956531
4Breast aplasia (HP:0100783)3.85052522
5Chromsome breakage (HP:0040012)3.84339970
6Abnormality of abdominal situs (HP:0011620)3.83483568
7Abdominal situs inversus (HP:0003363)3.83483568
8Patellar aplasia (HP:0006443)3.78015492
9Absent radius (HP:0003974)3.76172909
10Premature ovarian failure (HP:0008209)3.71977342
11Chromosomal breakage induced by crosslinking agents (HP:0003221)3.71532359
12Shawl scrotum (HP:0000049)3.67298349
13Aplasia/Hypoplasia of the breasts (HP:0010311)3.65237989
14Supernumerary spleens (HP:0009799)3.64247584
15Spastic diplegia (HP:0001264)3.62913360
16Absent forearm bone (HP:0003953)3.62302486
17Aplasia involving forearm bones (HP:0009822)3.62302486
18Chronic bronchitis (HP:0004469)3.59827161
19Oral leukoplakia (HP:0002745)3.56585491
20Hepatoblastoma (HP:0002884)3.47573572
21Aplasia/Hypoplasia of the patella (HP:0006498)3.44102125
22Carpal bone hypoplasia (HP:0001498)3.41363587
23Nephroblastoma (Wilms tumor) (HP:0002667)3.31921212
24Choanal stenosis (HP:0000452)3.27798162
25Medulloblastoma (HP:0002885)3.26215389
26Embryonal renal neoplasm (HP:0011794)3.16169017
27Reticulocytopenia (HP:0001896)3.14727208
28Bilateral microphthalmos (HP:0007633)3.08572700
29Rib fusion (HP:0000902)3.07053546
30Maternal diabetes (HP:0009800)3.07018308
31Multiple enchondromatosis (HP:0005701)3.04365154
32Abnormality of the labia minora (HP:0012880)2.91179995
33Absent thumb (HP:0009777)2.84700718
34Absent septum pellucidum (HP:0001331)2.82929604
35Abnormality of the septum pellucidum (HP:0007375)2.81602311
36Selective tooth agenesis (HP:0001592)2.78397929
37Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.77597589
38Homocystinuria (HP:0002156)2.74789060
39Abnormality of homocysteine metabolism (HP:0010919)2.74789060
40Aplasia/hypoplasia of the humerus (HP:0006507)2.72883685
41Abnormal lung lobation (HP:0002101)2.71761702
42Secondary amenorrhea (HP:0000869)2.68769534
43Cellular immunodeficiency (HP:0005374)2.66660345
44Overlapping toe (HP:0001845)2.65277337
45Male infertility (HP:0003251)2.64320239
46Meckel diverticulum (HP:0002245)2.62802062
47Horseshoe kidney (HP:0000085)2.60175403
48Rhabdomyosarcoma (HP:0002859)2.58825169
49Ependymoma (HP:0002888)2.56485915
50Abnormality of glycolysis (HP:0004366)2.56462857
51Increased serum pyruvate (HP:0003542)2.56462857
52Hypoplastic pelvis (HP:0008839)2.55883016
53Ectopic kidney (HP:0000086)2.53873625
54Short hallux (HP:0010109)2.48690216
55Hypoglycemic seizures (HP:0002173)2.44662637
56Abnormality of the ileum (HP:0001549)2.42906943
57Abnormality of pyrimidine metabolism (HP:0004353)2.41767379
58Short humerus (HP:0005792)2.40796309
59Hyperglycinuria (HP:0003108)2.40778480
60Hyperglycinemia (HP:0002154)2.39558890
61Abnormality of the preputium (HP:0100587)2.38021749
62Aplasia/Hypoplasia of the uvula (HP:0010293)2.36187812
63Aplasia/Hypoplasia of the hallux (HP:0008362)2.35280876
64Esophageal atresia (HP:0002032)2.32841071
65Facial cleft (HP:0002006)2.29262098
66Hypogonadotrophic hypogonadism (HP:0000044)2.29249314
67Cerebral hypomyelination (HP:0006808)2.26237973
68Trismus (HP:0000211)2.26185386
69Duplicated collecting system (HP:0000081)2.23910787
70Abnormality of serine family amino acid metabolism (HP:0010894)2.21044238
71Abnormality of glycine metabolism (HP:0010895)2.21044238
72Pancreatic islet-cell hyperplasia (HP:0004510)2.19491064
73Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.19474761
74Rough bone trabeculation (HP:0100670)2.19218260
75Anal stenosis (HP:0002025)2.18532021
76Partial duplication of thumb phalanx (HP:0009944)2.16925510
77Bifid tongue (HP:0010297)2.16013074
78Asplenia (HP:0001746)2.16001991
79Neoplasm of the adrenal cortex (HP:0100641)2.14606250
80Abnormality of serum amino acid levels (HP:0003112)2.14376182
81Myelomeningocele (HP:0002475)2.13731838
82Erectile abnormalities (HP:0100639)2.13697051
83Tracheoesophageal fistula (HP:0002575)2.12685865
84Aplastic anemia (HP:0001915)2.12570198
85Aqueductal stenosis (HP:0002410)2.12498314
86Short thumb (HP:0009778)2.10896875
87Abnormal number of incisors (HP:0011064)2.10715815
88Anosmia (HP:0000458)2.10638096
89Biliary tract neoplasm (HP:0100574)2.09754764
90Aplasia/Hypoplasia of the sternum (HP:0006714)2.08809056
91Neoplasm of striated muscle (HP:0009728)2.08687660
92Abnormality of chromosome stability (HP:0003220)2.08208146
93Facial hemangioma (HP:0000329)2.07760656
94Triphalangeal thumb (HP:0001199)2.07155501
95Long eyelashes (HP:0000527)2.06484502
96Neoplasm of the pancreas (HP:0002894)2.06347583
97Preauricular skin tag (HP:0000384)2.05594260
98Optic nerve hypoplasia (HP:0000609)2.05121195
99Impulsivity (HP:0100710)2.04955621
100Gastrointestinal carcinoma (HP:0002672)2.04720881
101Malignant gastrointestinal tract tumors (HP:0006749)2.04720881
102Agnosia (HP:0010524)2.03001345
103Stenosis of the external auditory canal (HP:0000402)2.02215506
104Atresia of the external auditory canal (HP:0000413)2.02073571
105Abnormality of the lacrimal duct (HP:0011481)2.01468712
106Vaginal fistula (HP:0004320)2.00172419
107Neoplasm of the oral cavity (HP:0100649)1.99313631
108Aplasia/Hypoplasia involving the musculature (HP:0001460)1.98782810
109Abnormal hair whorl (HP:0010721)1.98224536
110Oligodactyly (HP:0012165)1.96917824
111Primary amenorrhea (HP:0000786)1.95968633
112Cleft eyelid (HP:0000625)1.95584467
113Aplasia/Hypoplasia of the spleen (HP:0010451)1.93710389
114Skin tags (HP:0010609)1.92256892
115Skull defect (HP:0001362)1.92012919
116Hyperinsulinemic hypoglycemia (HP:0000825)1.91616245
117Gastrointestinal atresia (HP:0002589)1.91142613
118Sloping forehead (HP:0000340)1.87520535
119Cortical dysplasia (HP:0002539)1.87120743
120Intestinal atresia (HP:0011100)1.86859657
121Anophthalmia (HP:0000528)1.86377163
122Abnormality of the renal collecting system (HP:0004742)1.86067198
123Duplication of thumb phalanx (HP:0009942)1.85960034
124Absent eyebrow (HP:0002223)1.85879794
125Embryonal neoplasm (HP:0002898)1.85418157
126Uterine neoplasm (HP:0010784)1.85385177
127Deviation of the thumb (HP:0009603)1.84817048
128Duodenal stenosis (HP:0100867)1.84724772
129Small intestinal stenosis (HP:0012848)1.84724772
130Abnormality of methionine metabolism (HP:0010901)1.84048079
131Abnormality of aspartate family amino acid metabolism (HP:0010899)1.82847076
132Abnormality of the salivary glands (HP:0010286)1.81732417
133Abnormality of the proximal phalanges of the hand (HP:0009834)1.81008594
134Preaxial foot polydactyly (HP:0001841)1.80840117
135Abnormality of the clitoris (HP:0000056)1.79780365
136Humeroradial synostosis (HP:0003041)1.79555614
137Synostosis involving the elbow (HP:0003938)1.79555614
138Glioma (HP:0009733)1.79546402
139Fibular aplasia (HP:0002990)1.78397715
140Generalized hypotonia (HP:0001290)1.78219908
141Broad thumb (HP:0011304)1.77850506
142Hypoplastic female external genitalia (HP:0012815)1.77826962
143Abnormality of the anterior horn cell (HP:0006802)1.77209543
144Degeneration of anterior horn cells (HP:0002398)1.77209543
145High anterior hairline (HP:0009890)1.77074055
146Abnormal trabecular bone morphology (HP:0100671)1.76366659
147Septo-optic dysplasia (HP:0100842)1.76091831
148Abnormality of the duodenum (HP:0002246)1.75047857
149Hemivertebrae (HP:0002937)1.74274708
150Neoplasm of the colon (HP:0100273)1.73376058
151Intestinal fistula (HP:0100819)1.72665991
152Increased nuchal translucency (HP:0010880)1.71385025
153Hypoplasia of the radius (HP:0002984)1.71377850
154Rectovaginal fistula (HP:0000143)1.71330049
155Rectal fistula (HP:0100590)1.71330049
156Myelodysplasia (HP:0002863)1.70854312

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS25.21185113
2BUB14.63724174
3CDC74.25685146
4LATS13.74214820
5VRK23.49532081
6PLK43.03933656
7TTK2.95468951
8TAF12.92166821
9STK38L2.79053414
10TNIK2.72856543
11WEE12.56432105
12ZAK2.45718383
13NEK22.41032726
14CDK192.37707209
15ERBB42.31256762
16EIF2AK12.13820940
17MAP3K61.98908640
18KSR21.98747881
19PBK1.93431859
20CDK81.92085499
21PLK11.84762187
22CDK121.84223411
23STK101.83580170
24CDK71.79355058
25EEF2K1.76832200
26SMG11.76391918
27TESK21.71450305
28MAP3K81.70825574
29CHEK21.69281043
30PRKD31.66996738
31MST41.63236702
32BRAF1.61175113
33TSSK61.57011754
34SRPK11.48720766
35NUAK11.48199299
36AURKA1.45471286
37AURKB1.43723223
38MOS1.32975761
39MELK1.31868335
40PASK1.31860660
41MAP3K91.27837195
42FGFR21.27796132
43NME11.23334337
44WNK31.21238405
45PLK31.21156388
46CHEK11.20451971
47ATR1.16176964
48VRK11.12631740
49DYRK21.10584239
50DYRK31.07072781
51STK161.05653193
52NEK11.04657639
53RPS6KB21.04347987
54STK31.04225767
55CDK41.02402684
56STK240.98660937
57EPHA20.97001469
58PAK40.96711502
59TAOK10.96581746
60TGFBR10.95738537
61CAMK1D0.95037106
62KDR0.94857970
63BMX0.93658778
64PNCK0.93032375
65RPS6KA40.92071903
66ATM0.87959377
67CAMK1G0.85079681
68CDK20.84399048
69ACVR1B0.82875967
70ABL20.79795463
71MKNK10.78250412
72TRIM280.76136311
73PAK10.73062037
74EIF2AK20.72612764
75MAP3K100.72007208
76TIE10.71799449
77OXSR10.71292633
78CSNK1E0.64311082
79DMPK0.62827019
80RAF10.61735014
81CDK10.61512772
82STK40.61192710
83FGFR10.59877657
84BMPR1B0.59345379
85ALK0.57945960
86PIM10.57788742
87CSNK1G20.56628618
88CASK0.55135676
89MAP2K20.55033414
90MAP3K110.54907944
91TAOK30.54630264
92KSR10.54258741
93MTOR0.53409502
94BMPR20.53396382
95TLK10.53199305
96NLK0.52645289
97DAPK10.52571099
98SCYL20.52189471
99EIF2AK30.51885764
100CDK90.51860654
101AKT20.50225672
102STK380.49789728
103BRD40.48101735
104CSNK2A20.47631590
105MKNK20.45166468
106FLT30.44159956
107GRK60.44049891
108BRSK10.42712953
109MAPKAPK30.42255550
110MAP3K20.40799056
111CSNK1G30.40140488
112BRSK20.38715637
113PRKG20.37935960
114CSNK2A10.37933272
115EGFR0.36766721
116DYRK1A0.35833586
117BCKDK0.35740193
118PRKD20.35706616
119PRKCI0.35652350
120PLK20.33281803
121PRKDC0.33199207
122BCR0.30348131
123PTK20.30304530
124RPS6KA10.29833317
125GSK3B0.29540168
126FGFR40.28912019
127CDK60.28790034
128NTRK10.28563253
129ARAF0.27911713
130CSNK1D0.26295244
131CSNK1G10.25130221
132AKT10.24503578
133TYRO30.24238677
134MAP3K40.24135446
135MAP3K130.24089607
136TESK10.22768855
137PAK60.22682757

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.24736468
2RNA polymerase_Homo sapiens_hsa030203.96182687
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.90868391
4Mismatch repair_Homo sapiens_hsa034303.78659622
5RNA transport_Homo sapiens_hsa030133.54358353
6Spliceosome_Homo sapiens_hsa030403.35708240
7Cell cycle_Homo sapiens_hsa041103.02829483
8Base excision repair_Homo sapiens_hsa034102.88203946
9One carbon pool by folate_Homo sapiens_hsa006702.78870339
10Homologous recombination_Homo sapiens_hsa034402.76809707
11RNA degradation_Homo sapiens_hsa030182.76673361
12Basal transcription factors_Homo sapiens_hsa030222.53496197
13Nucleotide excision repair_Homo sapiens_hsa034202.53401612
14Proteasome_Homo sapiens_hsa030502.47369025
15Pyrimidine metabolism_Homo sapiens_hsa002402.41625068
16Ribosome_Homo sapiens_hsa030102.37203451
17Fanconi anemia pathway_Homo sapiens_hsa034602.22460518
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.18351159
19mRNA surveillance pathway_Homo sapiens_hsa030152.17343774
20Cysteine and methionine metabolism_Homo sapiens_hsa002702.03636703
21Non-homologous end-joining_Homo sapiens_hsa034501.66076102
22Oocyte meiosis_Homo sapiens_hsa041141.64410655
23Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.52769485
24Basal cell carcinoma_Homo sapiens_hsa052171.44389373
25Hippo signaling pathway_Homo sapiens_hsa043901.38468606
26p53 signaling pathway_Homo sapiens_hsa041151.37118999
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.35845580
28Purine metabolism_Homo sapiens_hsa002301.32149696
29Biosynthesis of amino acids_Homo sapiens_hsa012301.25104601
30Steroid biosynthesis_Homo sapiens_hsa001001.23349573
31Protein export_Homo sapiens_hsa030601.22606388
32Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21902412
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.19925015
34TGF-beta signaling pathway_Homo sapiens_hsa043501.17464803
35MicroRNAs in cancer_Homo sapiens_hsa052061.16180077
36Thyroid cancer_Homo sapiens_hsa052161.12232358
37Parkinsons disease_Homo sapiens_hsa050121.10859991
38Hedgehog signaling pathway_Homo sapiens_hsa043401.09965222
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.05959651
40Propanoate metabolism_Homo sapiens_hsa006401.05077302
41Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.03771877
42Oxidative phosphorylation_Homo sapiens_hsa001900.97213490
43Vitamin B6 metabolism_Homo sapiens_hsa007500.94217595
44Vitamin digestion and absorption_Homo sapiens_hsa049770.92972596
45Melanoma_Homo sapiens_hsa052180.89339607
46Epstein-Barr virus infection_Homo sapiens_hsa051690.85934802
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.84145777
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81618795
49Colorectal cancer_Homo sapiens_hsa052100.79678337
50Adherens junction_Homo sapiens_hsa045200.76685236
51Ovarian steroidogenesis_Homo sapiens_hsa049130.75809192
52Bladder cancer_Homo sapiens_hsa052190.75691430
53Linoleic acid metabolism_Homo sapiens_hsa005910.72566764
54HTLV-I infection_Homo sapiens_hsa051660.71917877
55Central carbon metabolism in cancer_Homo sapiens_hsa052300.71811885
56Wnt signaling pathway_Homo sapiens_hsa043100.68329084
57Folate biosynthesis_Homo sapiens_hsa007900.68028805
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67506497
59Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.67504954
60Fatty acid elongation_Homo sapiens_hsa000620.66454322
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66285395
62alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63518367
63mTOR signaling pathway_Homo sapiens_hsa041500.62766336
64Selenocompound metabolism_Homo sapiens_hsa004500.61757064
65Cyanoamino acid metabolism_Homo sapiens_hsa004600.60078234
66Notch signaling pathway_Homo sapiens_hsa043300.57948113
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57601707
68Viral carcinogenesis_Homo sapiens_hsa052030.56897704
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.56293838
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.56116576
71HIF-1 signaling pathway_Homo sapiens_hsa040660.54753430
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.51734240
73Pyruvate metabolism_Homo sapiens_hsa006200.51454651
74Systemic lupus erythematosus_Homo sapiens_hsa053220.51301464
75Alzheimers disease_Homo sapiens_hsa050100.50614663
76beta-Alanine metabolism_Homo sapiens_hsa004100.46103101
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.45693480
78Cardiac muscle contraction_Homo sapiens_hsa042600.44557876
79Tight junction_Homo sapiens_hsa045300.44252605
80Pathways in cancer_Homo sapiens_hsa052000.42940478
81Galactose metabolism_Homo sapiens_hsa000520.42503235
82Sulfur relay system_Homo sapiens_hsa041220.41132580
83Carbon metabolism_Homo sapiens_hsa012000.40254341
84Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39180478
85Drug metabolism - other enzymes_Homo sapiens_hsa009830.37017524
86Herpes simplex infection_Homo sapiens_hsa051680.36501061
87Endometrial cancer_Homo sapiens_hsa052130.35892717
88Arginine and proline metabolism_Homo sapiens_hsa003300.34153327
89Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.33716243
90Fatty acid metabolism_Homo sapiens_hsa012120.33418985
91Small cell lung cancer_Homo sapiens_hsa052220.32570759
92Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32241666
93Pentose phosphate pathway_Homo sapiens_hsa000300.31407167
94Arginine biosynthesis_Homo sapiens_hsa002200.31337207
95Retinol metabolism_Homo sapiens_hsa008300.31247786
96Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.31137445
97Lysine degradation_Homo sapiens_hsa003100.30930117
98Ether lipid metabolism_Homo sapiens_hsa005650.29776627
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29679469
100Huntingtons disease_Homo sapiens_hsa050160.29640733
101Phenylalanine metabolism_Homo sapiens_hsa003600.29626433
102Renal cell carcinoma_Homo sapiens_hsa052110.27956701
103Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27470472
104Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.27133043
105Melanogenesis_Homo sapiens_hsa049160.26048721
106Pancreatic cancer_Homo sapiens_hsa052120.25861786
107Fatty acid degradation_Homo sapiens_hsa000710.23250275
108Glutathione metabolism_Homo sapiens_hsa004800.23066029
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.22035336
110Prostate cancer_Homo sapiens_hsa052150.21616474
111Shigellosis_Homo sapiens_hsa051310.21316134
112GnRH signaling pathway_Homo sapiens_hsa049120.20342640
113Glucagon signaling pathway_Homo sapiens_hsa049220.17147434
114Rap1 signaling pathway_Homo sapiens_hsa040150.16007205
115Fat digestion and absorption_Homo sapiens_hsa049750.15669131
116Regulation of actin cytoskeleton_Homo sapiens_hsa048100.15257053
117Taste transduction_Homo sapiens_hsa047420.14644690
1182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.14302879
119Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.14202927
120Ras signaling pathway_Homo sapiens_hsa040140.14157019
121Non-small cell lung cancer_Homo sapiens_hsa052230.14076761
122Chronic myeloid leukemia_Homo sapiens_hsa052200.13569493
123Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.11633727
124Renin-angiotensin system_Homo sapiens_hsa046140.11574651
125Apoptosis_Homo sapiens_hsa042100.11370721
126Circadian rhythm_Homo sapiens_hsa047100.11100198
127Longevity regulating pathway - mammal_Homo sapiens_hsa042110.10966762
128Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.10634742
129Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.10517823
130Metabolic pathways_Homo sapiens_hsa011000.10451216
131Tyrosine metabolism_Homo sapiens_hsa003500.09598257
132Transcriptional misregulation in cancer_Homo sapiens_hsa052020.08797040
133VEGF signaling pathway_Homo sapiens_hsa043700.08490290

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