VSIG8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1virion attachment to host cell (GO:0019062)9.37500935
2adhesion of symbiont to host cell (GO:0044650)9.37500935
3peptide cross-linking (GO:0018149)8.67198475
4citrulline biosynthetic process (GO:0019240)8.10343760
5adhesion of symbiont to host (GO:0044406)7.91834197
6cell wall macromolecule catabolic process (GO:0016998)7.56123876
7cell wall macromolecule metabolic process (GO:0044036)7.56123876
8hair follicle morphogenesis (GO:0031069)7.49785908
9establishment of skin barrier (GO:0061436)7.05425408
10epidermis development (GO:0008544)6.26355398
11regulation of water loss via skin (GO:0033561)6.26035082
12intermediate filament cytoskeleton organization (GO:0045104)6.20975222
13keratinocyte differentiation (GO:0030216)6.14379476
14intermediate filament-based process (GO:0045103)6.00453391
15hemidesmosome assembly (GO:0031581)5.73496344
16linoleic acid metabolic process (GO:0043651)5.60010844
17bundle of His cell to Purkinje myocyte communication (GO:0086069)5.52433716
18skin morphogenesis (GO:0043589)5.46388353
19citrulline metabolic process (GO:0000052)5.31768557
20hair cycle process (GO:0022405)5.15184979
21molting cycle process (GO:0022404)5.15184979
22epidermal cell differentiation (GO:0009913)4.80028688
23tooth mineralization (GO:0034505)4.49542559
24peptidyl-arginine modification (GO:0018195)4.40365406
25multicellular organismal water homeostasis (GO:0050891)4.26889578
26keratinocyte development (GO:0003334)4.06252400
27molting cycle (GO:0042303)31.6916770
28hair cycle (GO:0042633)31.6916770
29retinol metabolic process (GO:0042572)3.96725239
30lipoxygenase pathway (GO:0019372)3.96434672
31long-chain fatty acid biosynthetic process (GO:0042759)3.74087983
32water homeostasis (GO:0030104)3.48743811
33primary alcohol catabolic process (GO:0034310)3.46611152
34negative regulation of keratinocyte proliferation (GO:0010839)3.42071578
35hair follicle development (GO:0001942)3.39787622
36regulation of keratinocyte differentiation (GO:0045616)3.35138098
37detection of bacterium (GO:0016045)3.21392257
38positive regulation of hair follicle development (GO:0051798)3.20777513
39positive regulation of hair cycle (GO:0042635)3.20777513
40primary alcohol metabolic process (GO:0034308)3.17071567
41regulation of hair follicle development (GO:0051797)3.15301340
42thioester biosynthetic process (GO:0035384)3.12191805
43acyl-CoA biosynthetic process (GO:0071616)3.12191805
44atrioventricular valve morphogenesis (GO:0003181)3.09807323
45ectoderm development (GO:0007398)3.00449733
46detection of other organism (GO:0098543)2.99996179
47positive regulation of chemokine secretion (GO:0090197)2.98249389
48fatty acid elongation (GO:0030497)2.98020671
49fatty-acyl-CoA metabolic process (GO:0035337)2.96731003
50bone trabecula formation (GO:0060346)2.96451838
51negative regulation of establishment of protein localization to plasma membrane (GO:0090005)2.96382481
52epithelium development (GO:0060429)2.96040701
53ethanol metabolic process (GO:0006067)2.94547654
54negative regulation of cell fate specification (GO:0009996)2.94332809
55axonemal dynein complex assembly (GO:0070286)2.93510663
56phosphatidylinositol acyl-chain remodeling (GO:0036149)2.90420938
57regulation of chemokine secretion (GO:0090196)2.82870026
58one-carbon compound transport (GO:0019755)2.77661687
59defense response to fungus (GO:0050832)2.75035525
60regulation of hair cycle (GO:0042634)2.74489325
61positive regulation of keratinocyte differentiation (GO:0045618)2.74308054
62positive regulation of epidermis development (GO:0045684)2.72906922
63lymph vessel development (GO:0001945)2.71625807
64skin development (GO:0043588)2.68385941
65positive regulation of meiotic cell cycle (GO:0051446)2.67395558
66ventricular cardiac muscle cell action potential (GO:0086005)2.65559471
67regulation of epidermal cell differentiation (GO:0045604)2.64040594
68phosphatidylserine acyl-chain remodeling (GO:0036150)2.62040916
69alpha-linolenic acid metabolic process (GO:0036109)2.60319753
70regulation of epidermis development (GO:0045682)2.58762044
71gap junction assembly (GO:0016264)2.55822662
72epithelial cell differentiation involved in prostate gland development (GO:0060742)2.54095655
73myotube differentiation (GO:0014902)2.50576320
74regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.46521885
75negative regulation of protein localization to plasma membrane (GO:1903077)2.44325346
76regulation of sequestering of triglyceride (GO:0010889)2.43920645
77epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.43484724
78regulation of mesenchymal cell apoptotic process (GO:2001053)2.42758461
79cell surface receptor signaling pathway involved in heart development (GO:0061311)2.40140889
80regulation of cardioblast differentiation (GO:0051890)2.39710827
81cilium or flagellum-dependent cell motility (GO:0001539)2.38935502
82cytoskeletal anchoring at plasma membrane (GO:0007016)2.38722622
83phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.37494463
84wound healing, spreading of epidermal cells (GO:0035313)2.36202262
85coronary vasculature morphogenesis (GO:0060977)2.36117298
86outflow tract septum morphogenesis (GO:0003148)2.34003834
87regulation of cardioblast proliferation (GO:0003264)2.33791129
88regulation of secondary heart field cardioblast proliferation (GO:0003266)2.33791129
89regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.28987319
90planar cell polarity pathway involved in neural tube closure (GO:0090179)2.27107019
91cell-substrate junction assembly (GO:0007044)2.22706049
92positive regulation of epidermal cell differentiation (GO:0045606)2.20853903
93negative regulation of erythrocyte differentiation (GO:0045647)2.20411754
94regulation of heart rate by cardiac conduction (GO:0086091)2.20039384
95regulation of natural killer cell differentiation (GO:0032823)2.19626053
96phosphatidylcholine acyl-chain remodeling (GO:0036151)2.19189525
97cell communication involved in cardiac conduction (GO:0086065)2.18826849
98epithelial cell-cell adhesion (GO:0090136)2.17059530
99unsaturated fatty acid biosynthetic process (GO:0006636)2.15763329
100regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.15665323
101negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.15450641
102killing of cells of other organism (GO:0031640)2.15197028
103disruption of cells of other organism (GO:0044364)2.15197028
104detection of external biotic stimulus (GO:0098581)2.09857824
105keratinocyte proliferation (GO:0043616)2.09001537
106negative regulation of cell fate commitment (GO:0010454)2.07813288
107phosphatidylserine metabolic process (GO:0006658)2.07783917
108cranial suture morphogenesis (GO:0060363)2.05736818
109outer ear morphogenesis (GO:0042473)2.04288087
110regulation of ruffle assembly (GO:1900027)2.03840011
111ephrin receptor signaling pathway (GO:0048013)2.03386131
112negative regulation of epidermis development (GO:0045683)2.03195697
113non-canonical Wnt signaling pathway (GO:0035567)2.02601865
114regulation of defense response to virus by host (GO:0050691)2.02428543
115antigen processing and presentation of endogenous antigen (GO:0019883)2.00502569
116keratinization (GO:0031424)12.6415226
117intermediate filament organization (GO:0045109)11.2681213
118desmosome organization (GO:0002934)10.6366263
119positive regulation of monocyte chemotaxis (GO:0090026)1.99986241
120response to phenylpropanoid (GO:0080184)1.99192357
121regulation of keratinocyte proliferation (GO:0010837)1.99138665
122triglyceride biosynthetic process (GO:0019432)1.98689974
123regulation of glucocorticoid metabolic process (GO:0031943)1.97888530
124positive regulation of antigen processing and presentation (GO:0002579)1.95902440
125antigen processing and presentation of endogenous peptide antigen (GO:0002483)1.93177247
126cilium movement (GO:0003341)1.92900614
127negative regulation of interferon-gamma production (GO:0032689)1.91522667
128lateral sprouting from an epithelium (GO:0060601)1.88525192
129acyl-CoA metabolic process (GO:0006637)1.88257021
130thioester metabolic process (GO:0035383)1.88257021
131phosphatidylethanolamine acyl-chain remodeling (GO:0036152)1.88168131
132neutral lipid biosynthetic process (GO:0046460)1.86606365
133acylglycerol biosynthetic process (GO:0046463)1.86606365
134carnitine metabolic process (GO:0009437)1.86264941
135long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)1.85791695
136L-serine transport (GO:0015825)1.84917085
137aging (GO:0007568)1.84540684
138ceramide biosynthetic process (GO:0046513)1.81380131
139G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071991.81311282
140muscle organ morphogenesis (GO:0048644)1.80330920
141regulation of transforming growth factor beta2 production (GO:0032909)1.77199293
142long-chain fatty-acyl-CoA metabolic process (GO:0035336)1.76863523
143prostaglandin biosynthetic process (GO:0001516)1.75465414
144prostanoid biosynthetic process (GO:0046457)1.75465414
145detection of biotic stimulus (GO:0009595)1.74373002
146regulation of cell fate specification (GO:0042659)1.73955020
147very long-chain fatty acid metabolic process (GO:0000038)1.73812900
148fatty-acyl-CoA biosynthetic process (GO:0046949)1.73669142
149antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)1.73311788
150establishment of planar polarity (GO:0001736)1.73166666
151establishment of tissue polarity (GO:0007164)1.73166666
152cellular response to antibiotic (GO:0071236)1.71309131

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human4.50417804
2P63_26484246_Chip-Seq_KERATINOCYTES_Human3.60303003
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.77154276
4CTCF_20526341_ChIP-Seq_ESCs_Human2.23836341
5TP63_17297297_ChIP-ChIP_HaCaT_Human13.0175743
6SOX9_24532713_ChIP-Seq_HFSC_Mouse1.99093857
7NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.98178220
8BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.88668906
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.78374966
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.75583101
11E2F1_20622854_ChIP-Seq_HELA_Human1.74387676
12TAF2_19829295_ChIP-Seq_ESCs_Human1.70149219
13TP53_20018659_ChIP-ChIP_R1E_Mouse1.66916784
14EGR1_19032775_ChIP-ChIP_M12_Human1.66756886
15RACK7_27058665_Chip-Seq_MCF-7_Human1.66011834
16P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.65748407
17* CTCF_27219007_Chip-Seq_Bcells_Human1.65210559
18DNAJC2_21179169_ChIP-ChIP_NT2_Human1.64979977
19ESR1_21235772_ChIP-Seq_MCF-7_Human1.61819986
20ERG_20517297_ChIP-Seq_VCAP_Human1.61706775
21RARG_19884340_ChIP-ChIP_MEFs_Mouse1.60945794
22FOXO3_23340844_ChIP-Seq_DLD1_Human1.60873875
23TP63_22573176_ChIP-Seq_HFKS_Human1.60723745
24NANOG_20526341_ChIP-Seq_ESCs_Human1.57387058
25* LXR_22292898_ChIP-Seq_THP-1_Human1.57073602
26VDR_21846776_ChIP-Seq_THP-1_Human1.56297586
27YY1_22570637_ChIP-Seq_MALME-3M_Human1.50623299
28SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.49054164
29SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.49054164
30PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.48748246
31BCL6_27268052_Chip-Seq_Bcells_Human1.47698545
32ESR2_21235772_ChIP-Seq_MCF-7_Human1.47315817
33UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.46865979
34* CSB_26484114_Chip-Seq_FIBROBLAST_Human1.46441563
35IRF8_22096565_ChIP-ChIP_GC-B_Human1.41539213
36P53_21459846_ChIP-Seq_SAOS-2_Human1.41275197
37TRIM28_21343339_ChIP-Seq_HEK293_Human1.39905707
38MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse1.39044759
39BCOR_27268052_Chip-Seq_Bcells_Human1.38857129
40* TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.37723647
41ATF3_27146783_Chip-Seq_COLON_Human1.37306687
42IKZF1_21737484_ChIP-ChIP_HCT116_Human1.36655127
43ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.36271568
44KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30336011
45* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.29355530
46* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28737388
47SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.27839991
48KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.27384880
49STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26046028
50SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.25829935
51TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25044918
52ELF1_20517297_ChIP-Seq_JURKAT_Human1.24003490
53KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.23960407
54P68_20966046_ChIP-Seq_HELA_Human1.23258292
55ZNF263_19887448_ChIP-Seq_K562_Human1.23008136
56GATA1_22025678_ChIP-Seq_K562_Human1.22852337
57AHR_22903824_ChIP-Seq_MCF-7_Human1.22305781
58PHF8_20622854_ChIP-Seq_HELA_Human1.20092708
59CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.20018549
60ARNT_22903824_ChIP-Seq_MCF-7_Human1.19604281
61P300_27268052_Chip-Seq_Bcells_Human1.19406622
62SMC4_20622854_ChIP-Seq_HELA_Human1.18465693
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.16464302
64* VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.15499706
65SCL_19346495_ChIP-Seq_HPC-7_Human1.15444439
66P300_27058665_Chip-Seq_ZR-75-30cells_Human1.14947182
67TP63_23658742_ChIP-Seq_EP156T_Human1.14437918
68* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.13193788
69CEBPB_22108803_ChIP-Seq_LS180_Human1.12884782
70GATA3_24758297_ChIP-Seq_MCF-7_Human1.12470824
71EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.11292861
72UBF1/2_26484160_Chip-Seq_HMECs_Human1.11087488
73* SA1_27219007_Chip-Seq_ERYTHROID_Human1.10477712
74EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.09654187
75ELK4_26923725_Chip-Seq_MESODERM_Mouse1.08433021
76JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08098500
77STAT1_20625510_ChIP-Seq_HELA_Human1.07430252
78RAC3_21632823_ChIP-Seq_H3396_Human1.07125087
79* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.07034888
80TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06782880
81KDM2B_26808549_Chip-Seq_DND41_Human1.03553654
82SOX2_21211035_ChIP-Seq_LN229_Human1.02786284
83CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02754479
84SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02637901
85KLF5_25053715_ChIP-Seq_YYC3_Human1.02328359
86RUNX1_27514584_Chip-Seq_MCF-7_Human1.02004300
87JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01913109
88GATA4_25053715_ChIP-Seq_YYC3_Human1.01004873
89RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.00808257
90AR_21572438_ChIP-Seq_LNCaP_Human1.00659146
91ERG_21242973_ChIP-ChIP_JURKAT_Human0.99682131
92SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98400740
93EZH2_27304074_Chip-Seq_ESCs_Mouse0.97873821
94ZFP281_18757296_ChIP-ChIP_E14_Mouse0.96594615
95E2F1_17053090_ChIP-ChIP_MCF-7_Human0.96458241
96* SA1_27219007_Chip-Seq_Bcells_Human0.96369384
97RXR_22108803_ChIP-Seq_LS180_Human0.96234617
98GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.95882866
99STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.94930176
100NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.94353870
101ELK3_25401928_ChIP-Seq_HUVEC_Human0.94186329
102* RING1B_27294783_Chip-Seq_ESCs_Mouse0.93249317
103PPARA_22158963_ChIP-Seq_LIVER_Mouse0.93093850
104SOX2_27498859_Chip-Seq_STOMACH_Mouse0.92935287
105GATA1_19941826_ChIP-Seq_K562_Human0.92891122
106SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92597988
107EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.92134864
108SOX2_20726797_ChIP-Seq_SW620_Human0.90938759
109FOXH1_21741376_ChIP-Seq_ESCs_Human0.90884054
110TP53_18474530_ChIP-ChIP_U2OS_Human0.90278343
111SPI1_20517297_ChIP-Seq_HL60_Human0.89246548
112GATA6_21074721_ChIP-Seq_CACO-2_Human0.89007503
113* EZH2_27294783_Chip-Seq_ESCs_Mouse0.88822568
114SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.88618176
115RNF2_18974828_ChIP-Seq_MESCs_Mouse0.88275158
116EZH2_18974828_ChIP-Seq_MESCs_Mouse0.88275158
117JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.87145977
118THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86900429
119* RNF2_27304074_Chip-Seq_ESCs_Mouse0.86571001
120PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.85791437
121* SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.85603451
122RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.85379246
123KDM2B_26808549_Chip-Seq_K562_Human0.85044427
124RXR_22158963_ChIP-Seq_LIVER_Mouse0.84841297
125TCF7_22412390_ChIP-Seq_EML_Mouse0.84172883
126SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.83774264
127VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.83753570
128RUNX1_22412390_ChIP-Seq_EML_Mouse0.83624550
129ZNF217_24962896_ChIP-Seq_MCF-7_Human0.82573235
130CLOCK_20551151_ChIP-Seq_293T_Human0.82225178
131VDR_24763502_ChIP-Seq_THP-1_Human0.81905838
132EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.81612511
133ERA_21632823_ChIP-Seq_H3396_Human0.81213123
134TBX20_22328084_ChIP-Seq_HEART_Mouse0.80576486
135TBX20_22080862_ChIP-Seq_HEART_Mouse0.80576486

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000579_abnormal_nail_morphology7.29198865
2MP0002098_abnormal_vibrissa_morphology6.52176076
3MP0002796_impaired_skin_barrier6.34590014
4MP0000647_abnormal_sebaceous_gland6.01627755
5MP0005275_abnormal_skin_tensile5.57006955
6MP0010234_abnormal_vibrissa_follicle4.88516066
7MP0000383_abnormal_hair_follicle4.30424754
8MP0005501_abnormal_skin_physiology3.91451229
9MP0000377_abnormal_hair_follicle3.82985281
10MP0010678_abnormal_skin_adnexa3.80425503
11MP0003705_abnormal_hypodermis_morpholog3.78343310
12MP0000427_abnormal_hair_cycle3.54645931
13MP0002254_reproductive_system_inflammat3.30878161
14MP0001216_abnormal_epidermal_layer2.75980218
15MP0002060_abnormal_skin_morphology2.45207175
16MP0010771_integument_phenotype2.41300870
17MP0004381_abnormal_hair_follicle2.38799292
18MP0004947_skin_inflammation2.33695408
19MP0003878_abnormal_ear_physiology2.33143587
20MP0005377_hearing/vestibular/ear_phenot2.33143587
21MP0002234_abnormal_pharynx_morphology2.32966033
22MP0001243_abnormal_dermal_layer2.21838670
23MP0000367_abnormal_coat/_hair2.20422950
24MP0003453_abnormal_keratinocyte_physiol2.11561805
25MP0000467_abnormal_esophagus_morphology1.88369965
26MP0000762_abnormal_tongue_morphology1.62207623
27MP0009931_abnormal_skin_appearance1.54831732
28MP0003566_abnormal_cell_adhesion1.54343725
29MP0003941_abnormal_skin_development1.26814912
30MP0009053_abnormal_anal_canal1.24860084
31MP0004185_abnormal_adipocyte_glucose1.18195048
32MP0008438_abnormal_cutaneous_collagen1.13364353
33MP0001191_abnormal_skin_condition1.09926990
34MP0005409_darkened_coat_color1.04174330
35MP0001188_hyperpigmentation1.02506849
36MP0002095_abnormal_skin_pigmentation0.98678731
37MP0005647_abnormal_sex_gland0.90058599
38MP0000015_abnormal_ear_pigmentation0.88517805
39MP0004885_abnormal_endolymph0.86239069
40MP0001849_ear_inflammation0.85589200
41MP0001851_eye_inflammation0.84222485
42MP0004782_abnormal_surfactant_physiolog0.77799328
43MP0001346_abnormal_lacrimal_gland0.76176697
44MP0003191_abnormal_cellular_cholesterol0.74512591
45MP0005503_abnormal_tendon_morphology0.74491597
46MP0004264_abnormal_extraembryonic_tissu0.73664671
47MP0001340_abnormal_eyelid_morphology0.71081176
48MP0002249_abnormal_larynx_morphology0.69803937
49MP0003724_increased_susceptibility_to0.69669871
50MP0000678_abnormal_parathyroid_gland0.69411061
51MP0002877_abnormal_melanocyte_morpholog0.69197432
52MP0010030_abnormal_orbit_morphology0.66234865
53MP0005174_abnormal_tail_pigmentation0.64904614
54MP0009780_abnormal_chondrocyte_physiolo0.62474563
55MP0000566_synostosis0.61026119
56MP0009379_abnormal_foot_pigmentation0.60881908
57MP0006035_abnormal_mitochondrial_morpho0.59297437
58MP0004043_abnormal_pH_regulation0.58349494
59MP0002282_abnormal_trachea_morphology0.57052002
60MP0005451_abnormal_body_composition0.56384042
61MP0000627_abnormal_mammary_gland0.54170172
62MP0001784_abnormal_fluid_regulation0.51737938
63MP0003755_abnormal_palate_morphology0.51625323
64MP0005023_abnormal_wound_healing0.49014284
65MP0002653_abnormal_ependyma_morphology0.48496441
66MP0003315_abnormal_perineum_morphology0.48272944
67MP0004272_abnormal_basement_membrane0.45390042
68MP0003638_abnormal_response/metabolism_0.43905218
69MP0002970_abnormal_white_adipose0.43685423
70MP0002177_abnormal_outer_ear0.42013583
71MP0000751_myopathy0.40551538
72MP0001485_abnormal_pinna_reflex0.40082238
73MP0002111_abnormal_tail_morphology0.40006610
74MP0001879_abnormal_lymphatic_vessel0.38450459
75MP0003385_abnormal_body_wall0.38382595
76MP0000685_abnormal_immune_system0.37779927
77MP0001661_extended_life_span0.37200269
78MP0005666_abnormal_adipose_tissue0.37110118
79MP0002132_abnormal_respiratory_system0.36420421
80MP0003436_decreased_susceptibility_to0.36086518
81MP0005375_adipose_tissue_phenotype0.34118502
82MP0002009_preneoplasia0.33189602
83MP0000465_gastrointestinal_hemorrhage0.32801023
84MP0001533_abnormal_skeleton_physiology0.32363017
85MP0005535_abnormal_body_temperature0.31522760
86MP0000733_abnormal_muscle_development0.26954632
87MP0005025_abnormal_response_to0.26519035
88MP0010352_gastrointestinal_tract_polyps0.25856836
89MP0000538_abnormal_urinary_bladder0.25269757
90MP0006054_spinal_hemorrhage0.25018605
91MP0005390_skeleton_phenotype0.24877411
92MP0003763_abnormal_thymus_physiology0.24177231
93MP0005076_abnormal_cell_differentiation0.23464469
94MP0003045_fibrosis0.22960430
95MP0005464_abnormal_platelet_physiology0.22784864
96MP0000537_abnormal_urethra_morphology0.22770009
97MP0000013_abnormal_adipose_tissue0.22175915
98MP0005257_abnormal_intraocular_pressure0.21631486
99MP0004858_abnormal_nervous_system0.21098135
100MP0005248_abnormal_Harderian_gland0.21052518
101MP0001958_emphysema0.21046770
102MP0001765_abnormal_ion_homeostasis0.21043562
103MP0002697_abnormal_eye_size0.21026555
104MP0009278_abnormal_bone_marrow0.20661744
105MP0001984_abnormal_olfaction0.20350632
106MP0000432_abnormal_head_morphology0.20139897
107MP0003300_gastrointestinal_ulcer0.19943503
108MP0000858_altered_metastatic_potential0.19329137
109MP0003279_aneurysm0.19179952
110MP0003935_abnormal_craniofacial_develop0.18558336
111MP0009840_abnormal_foam_cell0.17731582
112MP0003448_altered_tumor_morphology0.17416661
113MP0005075_abnormal_melanosome_morpholog0.16237748
114MP0000462_abnormal_digestive_system0.16182675
115MP0000747_muscle_weakness0.15838819
116MP0003075_altered_response_to0.15528267
117MP0004019_abnormal_vitamin_homeostasis0.15402323
118MP0002971_abnormal_brown_adipose0.15119359
119MP0000750_abnormal_muscle_regeneration0.14980326
120MP0004130_abnormal_muscle_cell0.14810174
121MP0003011_delayed_dark_adaptation0.14551656
122MP0002909_abnormal_adrenal_gland0.14504819
123MP0008961_abnormal_basal_metabolism0.14114770
124MP0002277_abnormal_respiratory_mucosa0.14102352
125MP0000759_abnormal_skeletal_muscle0.13934258
126MP0005508_abnormal_skeleton_morphology0.13773298
127MP0001348_abnormal_lacrimal_gland0.13746275
128MP0008569_lethality_at_weaning0.13368858
129MP0003329_amyloid_beta_deposits0.13336124
130MP0000003_abnormal_adipose_tissue0.13247178
131MP0001800_abnormal_humoral_immune0.12784811
132MP0002233_abnormal_nose_morphology0.12704789
133MP0000428_abnormal_craniofacial_morphol0.12388133
134MP0005388_respiratory_system_phenotype0.12378119
135MP0002133_abnormal_respiratory_system0.12378119
136MP0000749_muscle_degeneration0.11919454
137MP0000681_abnormal_thyroid_gland0.11692813
138MP0002148_abnormal_hypersensitivity_rea0.11639951
139MP0002419_abnormal_innate_immunity0.11631983

Predicted human phenotypes

RankGene SetZ-score
1Slow-growing hair (HP:0002217)9.57642828
2Abnormality of hair growth rate (HP:0011363)9.57642828
3Pili torti (HP:0003777)8.98867174
4Brittle hair (HP:0002299)8.83386899
5Nail dystrophy (HP:0008404)6.78109987
6Abnormality of nail color (HP:0100643)6.17146351
7Fragile nails (HP:0001808)6.03292332
8Abnormal hair laboratory examination (HP:0003328)5.64867115
9Increased IgE level (HP:0003212)5.62838891
10Onycholysis (HP:0001806)5.45772024
11Palmoplantar hyperkeratosis (HP:0000972)4.96625077
12Alopecia of scalp (HP:0002293)4.87674922
13Plantar hyperkeratosis (HP:0007556)4.75686182
14Absent eyebrow (HP:0002223)4.71980144
15Palmar hyperkeratosis (HP:0010765)4.66507932
16Fine hair (HP:0002213)4.56929242
17Right ventricular cardiomyopathy (HP:0011663)4.50206919
18Absent hair (HP:0002298)4.44743396
19Thick nail (HP:0001805)4.35703351
20Follicular hyperkeratosis (HP:0007502)4.27874943
21Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.06982340
22Abnormality of secondary sexual hair (HP:0009888)3.94894218
23Abnormality of the axillary hair (HP:0100134)3.94894218
24Erythema (HP:0010783)3.74161460
25Milia (HP:0001056)3.69800806
26Oral leukoplakia (HP:0002745)3.47458694
27Sparse eyelashes (HP:0000653)3.42507740
28Amelogenesis imperfecta (HP:0000705)3.18951236
29Erythroderma (HP:0001019)3.16284397
30Abnormality of the frontal sinuses (HP:0002687)3.01147313
31Ridged nail (HP:0001807)2.82294132
32Congenital ichthyosiform erythroderma (HP:0007431)2.81210044
33Aplasia cutis congenita (HP:0001057)2.78315892
34Curly hair (HP:0002212)2.66639004
35Abnormal blistering of the skin (HP:0008066)2.59396693
36Parakeratosis (HP:0001036)2.50408708
37Congenital, generalized hypertrichosis (HP:0004540)2.47645440
38Advanced eruption of teeth (HP:0006288)2.46808407
39Neck muscle weakness (HP:0000467)2.45031434
40Natal tooth (HP:0000695)2.36038908
41Conjunctival hamartoma (HP:0100780)2.28093895
42Intention tremor (HP:0002080)2.18037874
43Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.17372198
44Ventricular tachycardia (HP:0004756)2.13678853
45Corneal erosion (HP:0200020)2.12830631
46Palmoplantar keratoderma (HP:0000982)2.10509101
47Hypohidrosis (HP:0000966)2.09974426
48Type 1 muscle fiber predominance (HP:0003803)2.06669597
49Dry hair (HP:0011359)2.05810925
50Coarse hair (HP:0002208)2.03701897
51Hypotrichosis (HP:0001006)13.7252284
52Woolly hair (HP:0002224)10.7108980
53Eczematoid dermatitis (HP:0000976)1.97890125
54Urticaria (HP:0001025)1.96150122
55Pruritus (HP:0000989)1.94708634
56Unilateral renal agenesis (HP:0000122)1.94079765
57Round ear (HP:0100830)1.92956823
58Torticollis (HP:0000473)1.92222908
59Atrophic scars (HP:0001075)1.92064282
60Increased connective tissue (HP:0009025)1.87594865
61Difficulty walking (HP:0002355)1.86906866
62Hyporeflexia of lower limbs (HP:0002600)1.82248046
63Abnormal respiratory epithelium morphology (HP:0012253)1.81476120
64Abnormal respiratory motile cilium morphology (HP:0005938)1.81476120
65Abnormality of the parietal bone (HP:0002696)1.77159631
66Abnormal respiratory motile cilium physiology (HP:0012261)1.76060161
67Concave nail (HP:0001598)1.73877970
68Acanthosis nigricans (HP:0000956)1.73274124
69Abnormal ciliary motility (HP:0012262)1.71490354
70Distal arthrogryposis (HP:0005684)1.70815912
71Abnormality of the aortic arch (HP:0012303)1.70034917
72Abnormality of the neuromuscular junction (HP:0003398)1.67215583
73Fatigable weakness (HP:0003473)1.67215583
74Craniofacial dystonia (HP:0012179)1.66220376
75Sudden death (HP:0001699)1.65645667
76Abnormality of molar (HP:0011077)1.65112460
77Abnormality of molar morphology (HP:0011070)1.65112460
78Widely patent fontanelles and sutures (HP:0004492)1.64137077
79Ventricular fibrillation (HP:0001663)1.61394701
80Abnormality of the dental root (HP:0006486)1.61006043
81Taurodontia (HP:0000679)1.61006043
82Abnormality of permanent molar morphology (HP:0011071)1.61006043
83Abnormality of dental color (HP:0011073)1.60948032
84Blepharitis (HP:0000498)1.60320650
85Ectropion (HP:0000656)1.59393273
86Achilles tendon contracture (HP:0001771)1.58498325
87Hypergammaglobulinemia (HP:0010702)1.58345067
88Rhinitis (HP:0012384)1.57253922
89Abnormality of the pupil (HP:0000615)1.56271851
90Hamartoma of the eye (HP:0010568)1.56197246
91Nasal polyposis (HP:0100582)1.56148792
92Lip pit (HP:0100267)1.55817888
93Chronic bronchitis (HP:0004469)1.54697007
94Absent eyelashes (HP:0000561)1.53959246
95Distal lower limb muscle weakness (HP:0009053)1.53933867
96Gangrene (HP:0100758)1.53549410
97Ulnar deviation of the wrist (HP:0003049)1.52838069
98Absent/shortened dynein arms (HP:0200106)1.52796164
99Dynein arm defect of respiratory motile cilia (HP:0012255)1.52796164
100Furrowed tongue (HP:0000221)1.52303949
101Focal dystonia (HP:0004373)1.50457070
102Multifactorial inheritance (HP:0001426)1.49537704
103Fragile skin (HP:0001030)1.48544544
104Breast hypoplasia (HP:0003187)1.47960324
105Carious teeth (HP:0000670)1.46057396
106Abnormality of the Achilles tendon (HP:0005109)1.45903732
107Calcaneovalgus deformity (HP:0001848)1.42964192
108Abnormality of the dental pulp (HP:0006479)1.41602903
109Abnormality of the salivary glands (HP:0010286)1.41397162
110Anonychia (HP:0001798)1.40903843
111Muscle fiber inclusion bodies (HP:0100299)1.40668985
112Nemaline bodies (HP:0003798)1.40554959
113Skin ulcer (HP:0200042)1.40092365
114Recurrent corneal erosions (HP:0000495)1.39509157
115Craniofacial hyperostosis (HP:0004493)1.38641741
116Keratoconjunctivitis sicca (HP:0001097)1.37086410
117Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.36771186
118Elevated erythrocyte sedimentation rate (HP:0003565)1.35409506
119Abnormality of the nasal mucosa (HP:0000433)1.35063712
120Myopathic facies (HP:0002058)1.31856510
121Abnormality of the fingernails (HP:0001231)1.31498050
122Sparse scalp hair (HP:0002209)1.29410013
123Villous atrophy (HP:0011473)1.28787047
124Abnormality of small intestinal villus morphology (HP:0011472)1.28787047
125Laryngomalacia (HP:0001601)1.26452128
126Heterogeneous (HP:0001425)1.25925386
127Down-sloping shoulders (HP:0200021)1.25613944
128Hyperhidrosis (HP:0000975)1.19723953
129Bronchiectasis (HP:0002110)1.13540507
130Xerostomia (HP:0000217)1.08224644
131Dehydration (HP:0001944)1.06087975
132Conical tooth (HP:0000698)1.05505536
133Exercise-induced myalgia (HP:0003738)1.03349674
134Recurrent bacterial skin infections (HP:0005406)0.97606728
135Obstructive sleep apnea (HP:0002870)0.96771868
136Nasolacrimal duct obstruction (HP:0000579)0.96004732
137Dry skin (HP:0000958)0.92162186

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FER4.27177448
2ERN13.91973270
3EPHB23.90597044
4MAPKAPK33.90556982
5EPHA23.37637508
6TRIB33.07225482
7TTN2.88323903
8TAOK12.80262017
9MAP3K62.73276364
10BCKDK2.66170408
11PIK3CG2.63500835
12MAP3K32.61872531
13MAPK152.28567956
14MAP3K22.18696698
15EEF2K2.15548636
16PRPF4B2.09459902
17SMG12.07685760
18TBK11.92129517
19LATS11.87882789
20MAP3K111.82851197
21RPS6KB21.63040598
22OBSCN1.60800009
23EPHB11.51166728
24GRK61.42826044
25RIPK11.40920346
26MST1R1.33008611
27MAP2K31.27048212
28WNK31.24043416
29SIK11.23742716
30MAP2K61.22535217
31MAP3K11.20533462
32BLK1.20395801
33IRAK21.16989565
34CDK61.16783253
35KIT1.15024401
36LATS21.14208924
37FGFR11.13803316
38PTK61.13021393
39MAP3K101.09066113
40PKN21.08738896
41FGFR41.07966740
42NME11.06316524
43DAPK21.06301712
44FGFR21.05851040
45BCR1.02113280
46CSK1.01843901
47KSR21.01120163
48BMX0.99749744
49ACVR1B0.98936762
50MAPKAPK20.98708345
51ABL20.97645975
52MAPK70.95589641
53PDGFRA0.94704459
54ZAP700.92361329
55IKBKB0.90342164
56FGFR30.88332009
57LRRK20.87302578
58MAP3K70.86733921
59MYLK0.85060672
60PHKG20.83567766
61PHKG10.83567766
62ADRBK10.83520752
63MAP3K90.81080010
64CAMKK10.80356258
65NTRK20.80113254
66PRKD10.78915518
67SCYL20.77997633
68PTK20.76690673
69PBK0.76641285
70RPS6KA40.75108679
71PRKCH0.73760781
72NME20.72320159
73MAPKAPK50.70811358
74MAP3K120.70347609
75STK380.68435444
76NEK10.65486911
77PAK40.64198302
78BTK0.63667596
79EPHA30.62313071
80DYRK1B0.62134692
81MET0.60468286
82RET0.59863408
83TNK20.58807097
84MAP2K10.58757994
85STK38L0.57312902
86MAP2K40.56923701
87NEK90.55892298
88TGFBR20.54210365
89MAPK120.54084169
90MAP2K20.53455368
91ERBB20.53314469
92MAP4K10.52376327
93ERBB40.52276624
94TYK20.51900267
95IRAK40.50486863
96TAOK20.50247589
97RIPK40.48607443
98TRPM70.48210106
99PAK20.48167321
100TESK10.47265101
101MAP3K50.46946412
102RPS6KA10.45893464
103HCK0.45100499
104HIPK20.44701082
105JAK30.43625227
106PDK20.43322128
107CDK190.43265995
108IKBKE0.43228986
109GSK3A0.42383406
110CDC42BPA0.42069212
111BMPR1B0.41469754
112ICK0.41220203
113PDK10.41077573
114RPS6KL10.40398763
115RPS6KC10.40398763
116PIM20.40260719
117MAPK30.40260370
118STK240.39778064
119RPS6KA60.39319241
120TGFBR10.39239999
121JAK10.38979544
122PRKCD0.37794592
123TLK10.37623305
124PRKAA20.37439647
125DDR20.36726418
126PRKCI0.34940573
127MAPK110.34052209
128ALK0.33877888
129LMTK20.33259902
130PRKD20.32196016
131PDPK10.31851741
132FYN0.30996446
133PAK30.30830941
134FES0.28884889
135PAK60.28083727
136ILK0.27364843
137MARK20.27281627
138CLK10.26996140
139CSNK1E0.26374682
140SRC0.26021313
141JAK20.25730262

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.68245762
2Linoleic acid metabolism_Homo sapiens_hsa005913.54298608
3Fatty acid elongation_Homo sapiens_hsa000622.95262874
4Vitamin digestion and absorption_Homo sapiens_hsa049772.75212415
5Fat digestion and absorption_Homo sapiens_hsa049752.74180817
6Basal cell carcinoma_Homo sapiens_hsa052172.23929627
7Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.13464072
8Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.88255046
9Phenylalanine metabolism_Homo sapiens_hsa003601.85046729
10Ether lipid metabolism_Homo sapiens_hsa005651.77447663
11Melanogenesis_Homo sapiens_hsa049161.63969351
12VEGF signaling pathway_Homo sapiens_hsa043701.62049110
13Hedgehog signaling pathway_Homo sapiens_hsa043401.50477590
14Axon guidance_Homo sapiens_hsa043601.49616077
15Glioma_Homo sapiens_hsa052141.40919145
16Retinol metabolism_Homo sapiens_hsa008301.36826980
17Arachidonic acid metabolism_Homo sapiens_hsa005901.35135639
18Proteoglycans in cancer_Homo sapiens_hsa052051.34307491
19Ovarian steroidogenesis_Homo sapiens_hsa049131.28277979
20Acute myeloid leukemia_Homo sapiens_hsa052211.27624363
21GnRH signaling pathway_Homo sapiens_hsa049121.26370023
22ECM-receptor interaction_Homo sapiens_hsa045121.26340724
23Vascular smooth muscle contraction_Homo sapiens_hsa042701.22481012
24Histidine metabolism_Homo sapiens_hsa003401.21108995
25PPAR signaling pathway_Homo sapiens_hsa033201.20798202
26Dorso-ventral axis formation_Homo sapiens_hsa043201.19985660
27Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17523476
28Bladder cancer_Homo sapiens_hsa052191.12234544
29Hippo signaling pathway_Homo sapiens_hsa043901.11417660
30Glycerolipid metabolism_Homo sapiens_hsa005611.09100991
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.05797944
32Tight junction_Homo sapiens_hsa045301.04762799
33Thyroid cancer_Homo sapiens_hsa052161.03752614
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.03447984
35Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.03429636
36Long-term potentiation_Homo sapiens_hsa047201.03248308
37Adherens junction_Homo sapiens_hsa045201.02631102
38Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01052166
39Pancreatic secretion_Homo sapiens_hsa049720.98825664
40Endometrial cancer_Homo sapiens_hsa052130.98709886
41Amoebiasis_Homo sapiens_hsa051460.97370505
42Salivary secretion_Homo sapiens_hsa049700.97235243
43Estrogen signaling pathway_Homo sapiens_hsa049150.96414555
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.96403814
45Pertussis_Homo sapiens_hsa051330.94700422
46Collecting duct acid secretion_Homo sapiens_hsa049660.93115030
47Insulin resistance_Homo sapiens_hsa049310.91893452
48Gastric acid secretion_Homo sapiens_hsa049710.90466225
49Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89539959
50Renin secretion_Homo sapiens_hsa049240.89102311
51Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87199122
52Mineral absorption_Homo sapiens_hsa049780.87179373
53Non-small cell lung cancer_Homo sapiens_hsa052230.85240666
54Caffeine metabolism_Homo sapiens_hsa002320.84637477
55Tyrosine metabolism_Homo sapiens_hsa003500.82012433
56Leukocyte transendothelial migration_Homo sapiens_hsa046700.81915381
57Wnt signaling pathway_Homo sapiens_hsa043100.77487613
58Fatty acid metabolism_Homo sapiens_hsa012120.76729376
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.76718284
60Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.75896589
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.75813202
62Steroid biosynthesis_Homo sapiens_hsa001000.75652654
63Notch signaling pathway_Homo sapiens_hsa043300.75082378
64Focal adhesion_Homo sapiens_hsa045100.73070131
65Ras signaling pathway_Homo sapiens_hsa040140.72601389
66beta-Alanine metabolism_Homo sapiens_hsa004100.72591011
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.72019161
68Oxytocin signaling pathway_Homo sapiens_hsa049210.71798350
69Long-term depression_Homo sapiens_hsa047300.70693752
70Peroxisome_Homo sapiens_hsa041460.70460190
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70437370
72Glycerophospholipid metabolism_Homo sapiens_hsa005640.68355858
73Sphingolipid signaling pathway_Homo sapiens_hsa040710.68147069
74Chemical carcinogenesis_Homo sapiens_hsa052040.68086666
75Protein digestion and absorption_Homo sapiens_hsa049740.67697860
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.66890506
77Choline metabolism in cancer_Homo sapiens_hsa052310.65023083
78RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64174443
79Dilated cardiomyopathy_Homo sapiens_hsa054140.63631539
80Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63543329
81Insulin signaling pathway_Homo sapiens_hsa049100.63237789
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.62309455
83Staphylococcus aureus infection_Homo sapiens_hsa051500.61447960
84Renal cell carcinoma_Homo sapiens_hsa052110.61041578
85Phototransduction_Homo sapiens_hsa047440.60973354
86ABC transporters_Homo sapiens_hsa020100.60239797
87Synaptic vesicle cycle_Homo sapiens_hsa047210.59961292
88MicroRNAs in cancer_Homo sapiens_hsa052060.59925121
89Phospholipase D signaling pathway_Homo sapiens_hsa040720.59873394
90Malaria_Homo sapiens_hsa051440.58903166
91Platelet activation_Homo sapiens_hsa046110.58771903
92Phagosome_Homo sapiens_hsa041450.57932807
93Serotonergic synapse_Homo sapiens_hsa047260.56608073
94Central carbon metabolism in cancer_Homo sapiens_hsa052300.56161211
95Gap junction_Homo sapiens_hsa045400.53676352
96Rap1 signaling pathway_Homo sapiens_hsa040150.53299986
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52791691
98Salmonella infection_Homo sapiens_hsa051320.52713383
99Tuberculosis_Homo sapiens_hsa051520.52437612
100Toxoplasmosis_Homo sapiens_hsa051450.52234731
101Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.52053635
102Hepatitis C_Homo sapiens_hsa051600.51447259
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.50884389
104Nitrogen metabolism_Homo sapiens_hsa009100.50435541
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49167426
106Amphetamine addiction_Homo sapiens_hsa050310.48720754
107Fatty acid degradation_Homo sapiens_hsa000710.48588370
108Fatty acid biosynthesis_Homo sapiens_hsa000610.48522263
109Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.47855259
110Lysosome_Homo sapiens_hsa041420.47654354
111Leishmaniasis_Homo sapiens_hsa051400.47643378
112Olfactory transduction_Homo sapiens_hsa047400.47390770
113Sphingolipid metabolism_Homo sapiens_hsa006000.47252411
114mTOR signaling pathway_Homo sapiens_hsa041500.47127241
115Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.46721520
116Aldosterone synthesis and secretion_Homo sapiens_hsa049250.44590573
117Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.44571821
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.43501248
119Chronic myeloid leukemia_Homo sapiens_hsa052200.42141925
120Prolactin signaling pathway_Homo sapiens_hsa049170.41971857
121Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41298777
122Prion diseases_Homo sapiens_hsa050200.41007074
123Butanoate metabolism_Homo sapiens_hsa006500.40282541
124Osteoclast differentiation_Homo sapiens_hsa043800.39908358
125Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.39806907
126cGMP-PKG signaling pathway_Homo sapiens_hsa040220.39520305
127Endocytosis_Homo sapiens_hsa041440.39208764
128Regulation of autophagy_Homo sapiens_hsa041400.38197586
129Calcium signaling pathway_Homo sapiens_hsa040200.36770476
130Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.32063589
131Inositol phosphate metabolism_Homo sapiens_hsa005620.30104438
132Circadian rhythm_Homo sapiens_hsa047100.29733352
133Type I diabetes mellitus_Homo sapiens_hsa049400.27365491
134Graft-versus-host disease_Homo sapiens_hsa053320.26605650
135Hematopoietic cell lineage_Homo sapiens_hsa046400.26335634
136Autoimmune thyroid disease_Homo sapiens_hsa053200.24496115

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