VWA3A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.12416212
2axoneme assembly (GO:0035082)8.53585383
3motile cilium assembly (GO:0044458)8.39030644
4sensory perception of smell (GO:0007608)6.64299401
5GTP biosynthetic process (GO:0006183)6.45813477
6ventricular system development (GO:0021591)6.39924723
7nucleoside diphosphate phosphorylation (GO:0006165)6.37229497
8protein localization to cilium (GO:0061512)6.10388975
9regulation of cilium movement (GO:0003352)6.06263862
10intraciliary transport (GO:0042073)5.78423714
11left/right axis specification (GO:0070986)5.60063451
12UTP biosynthetic process (GO:0006228)5.37442058
13sperm motility (GO:0030317)5.34677957
14acrosome reaction (GO:0007340)5.08083170
15primary alcohol catabolic process (GO:0034310)5.06639678
16cilium organization (GO:0044782)4.97381741
17cilium assembly (GO:0042384)4.87823099
18UTP metabolic process (GO:0046051)4.72661561
19vitamin transmembrane transport (GO:0035461)4.66698245
20cilium morphogenesis (GO:0060271)4.62912965
21guanosine-containing compound biosynthetic process (GO:1901070)4.61617495
22multicellular organism reproduction (GO:0032504)4.59948399
23ethanol metabolic process (GO:0006067)4.46059740
24fusion of sperm to egg plasma membrane (GO:0007342)4.40413626
25cellular component assembly involved in morphogenesis (GO:0010927)4.23852811
26cell wall macromolecule metabolic process (GO:0044036)4.21877234
27cell wall macromolecule catabolic process (GO:0016998)4.21877234
28acrosome assembly (GO:0001675)4.12881052
29diterpenoid biosynthetic process (GO:0016102)4.10705350
30microtubule severing (GO:0051013)4.07550020
31single fertilization (GO:0007338)4.05819951
32microtubule bundle formation (GO:0001578)4.03017800
33sensory perception of chemical stimulus (GO:0007606)4.02044981
34intra-S DNA damage checkpoint (GO:0031573)3.97019294
35sperm-egg recognition (GO:0035036)3.95425800
36CTP biosynthetic process (GO:0006241)3.95320404
37CTP metabolic process (GO:0046036)3.95320404
38spermatid development (GO:0007286)3.90910150
39protein polyglutamylation (GO:0018095)3.89992381
40negative regulation of inclusion body assembly (GO:0090084)3.86724754
41centriole assembly (GO:0098534)3.84842401
42plasma membrane fusion (GO:0045026)3.71725501
43glomerular epithelial cell development (GO:0072310)3.70809261
44retinal rod cell development (GO:0046548)3.68915696
45lung epithelium development (GO:0060428)3.67537126
46lateral ventricle development (GO:0021670)3.66072698
47determination of left/right symmetry (GO:0007368)3.65977914
48response to xenobiotic stimulus (GO:0009410)3.62473269
49regulation of interleukin-5 production (GO:0032674)3.62185865
50establishment of planar polarity (GO:0001736)3.56038402
51establishment of tissue polarity (GO:0007164)3.56038402
52nucleotide phosphorylation (GO:0046939)3.55778379
53binding of sperm to zona pellucida (GO:0007339)3.54638917
54determination of bilateral symmetry (GO:0009855)3.50783417
55reproduction (GO:0000003)3.50310727
56cell-cell recognition (GO:0009988)3.46395774
57tolerance induction (GO:0002507)3.46278840
58negative regulation of T cell differentiation in thymus (GO:0033085)3.46013517
59specification of symmetry (GO:0009799)3.43775085
60pyrimidine-containing compound transmembrane transport (GO:0072531)3.37102413
61lateral sprouting from an epithelium (GO:0060601)3.35952009
62cytoplasmic microtubule organization (GO:0031122)3.34890643
63microtubule-based movement (GO:0007018)3.34285439
64piRNA metabolic process (GO:0034587)3.33877426
65pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.32547568
66ethanol oxidation (GO:0006069)3.32021391
67microtubule polymerization or depolymerization (GO:0031109)3.31950475
68cell projection assembly (GO:0030031)3.27074085
69fertilization (GO:0009566)3.23815195
70pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.23002439
71nucleoside diphosphate metabolic process (GO:0009132)3.21754690
72establishment of apical/basal cell polarity (GO:0035089)3.21026677
73negative regulation of immunoglobulin mediated immune response (GO:0002890)3.13588181
74negative regulation of B cell mediated immunity (GO:0002713)3.13588181
75one-carbon compound transport (GO:0019755)3.10582064
76negative regulation of humoral immune response (GO:0002921)3.08277477
77detection of calcium ion (GO:0005513)3.07272629
78male meiosis (GO:0007140)3.05209881
79centriole replication (GO:0007099)3.04279684
80microtubule depolymerization (GO:0007019)3.01356540
81calcium ion-dependent exocytosis (GO:0017156)2.98226437
82regulation of interleukin-13 production (GO:0032656)2.97848180
83pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.96768101
84microtubule-based process (GO:0007017)2.96403520
85retinoic acid metabolic process (GO:0042573)2.94438823
86positive regulation of smoothened signaling pathway (GO:0045880)2.93657555
87spermatogenesis (GO:0007283)2.93316226
88establishment or maintenance of monopolar cell polarity (GO:0061339)2.91813946
89establishment of monopolar cell polarity (GO:0061162)2.91813946
90male gamete generation (GO:0048232)2.91575937
91apical protein localization (GO:0045176)2.90407589
92gas transport (GO:0015669)2.90133596
93regulation of microtubule-based movement (GO:0060632)2.84585586
94sperm capacitation (GO:0048240)2.84490336
95left/right pattern formation (GO:0060972)2.81042299
96terpenoid biosynthetic process (GO:0016114)2.77032410
97regulation of female gonad development (GO:2000194)2.76640472
98regulation of germinal center formation (GO:0002634)2.75139931
99gamete generation (GO:0007276)2.74581299
100positive regulation of tolerance induction (GO:0002645)2.72327074
101ADP metabolic process (GO:0046031)2.69543617
102pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.67431781
103deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.67165230
104heart looping (GO:0001947)2.64784893
105retinal cone cell development (GO:0046549)2.62289200
106startle response (GO:0001964)2.62208214
107regulation of inclusion body assembly (GO:0090083)2.59993429
108asymmetric protein localization (GO:0008105)2.58313746
109exogenous drug catabolic process (GO:0042738)2.57461469
110negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.55186149
111smoothened signaling pathway (GO:0007224)2.51867173
112cAMP catabolic process (GO:0006198)2.51840793
113regulation of smoothened signaling pathway (GO:0008589)2.48781624
114renal system development (GO:0072001)2.47106625
115regulation of cilium assembly (GO:1902017)2.45564476
116DNA methylation involved in gamete generation (GO:0043046)2.45479191
117embryonic heart tube morphogenesis (GO:0003143)2.45415437
118calcium ion import (GO:0070509)2.45206759
119photoreceptor cell maintenance (GO:0045494)2.45001998
120positive regulation of meiosis (GO:0045836)2.43487462
121carnitine metabolic process (GO:0009437)2.38654062
122presynaptic membrane assembly (GO:0097105)2.38449849
123spermatid nucleus differentiation (GO:0007289)2.37906859
124O-glycan processing (GO:0016266)2.37890887
125cyclic nucleotide catabolic process (GO:0009214)2.37802673
126embryonic camera-type eye development (GO:0031076)2.36367554
127protein heterotetramerization (GO:0051290)2.35629550
128cell recognition (GO:0008037)2.35327320
129meiotic cell cycle (GO:0051321)2.35094444
130negative regulation of JUN kinase activity (GO:0043508)2.34914141
131membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.34685977
132protein refolding (GO:0042026)2.33309144
133purine ribonucleoside diphosphate metabolic process (GO:0009179)2.32818922
134purine nucleoside diphosphate metabolic process (GO:0009135)2.32818922
135hydrogen peroxide biosynthetic process (GO:0050665)2.32812962
136regulation of microtubule depolymerization (GO:0031114)2.31729562
137oxygen transport (GO:0015671)2.31252843
138regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.29975099
139nonmotile primary cilium assembly (GO:0035058)2.29773116
140positive regulation of meiotic cell cycle (GO:0051446)2.28963917
141negative regulation of oligodendrocyte differentiation (GO:0048715)2.28834136
142regulation of timing of cell differentiation (GO:0048505)2.25455942
143regulation of autophagic vacuole assembly (GO:2000785)2.23432301
144dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.22735879
145organelle assembly (GO:0070925)2.22539210
146primary alcohol metabolic process (GO:0034308)2.21653994
147limb development (GO:0060173)2.21340702
148appendage development (GO:0048736)2.21340702
149sodium ion homeostasis (GO:0055078)2.20676178
150multicellular organismal reproductive process (GO:0048609)2.19756068
151regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.18463346
152protein insertion into membrane (GO:0051205)2.17094922
153phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.16690090
154negative regulation of transcription regulatory region DNA binding (GO:2000678)2.16040395
155regulation of mononuclear cell migration (GO:0071675)2.15331227
156germ cell development (GO:0007281)2.14582567
157neuron cell-cell adhesion (GO:0007158)2.14554002
158cAMP metabolic process (GO:0046058)2.13938808
159phosphorelay signal transduction system (GO:0000160)2.13047375
160postsynaptic membrane organization (GO:0001941)2.12045297
161axonemal dynein complex assembly (GO:0070286)11.7107631
162cilium movement (GO:0003341)11.4555201
163cilium or flagellum-dependent cell motility (GO:0001539)10.3547353
164epithelial cilium movement (GO:0003351)10.0268161

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.68030840
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.22388252
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.65406842
4GBX2_23144817_ChIP-Seq_PC3_Human3.14606072
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.62669302
6FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.48810787
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.44646552
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30500118
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.14136321
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.10787974
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.10740359
12AR_21572438_ChIP-Seq_LNCaP_Human2.02250327
13CBX2_27304074_Chip-Seq_ESCs_Mouse1.84950851
14ESR1_20079471_ChIP-ChIP_T-47D_Human1.81493518
15SMAD4_21799915_ChIP-Seq_A2780_Human1.79373210
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.78513770
17SUZ12_27294783_Chip-Seq_NPCs_Mouse1.76935998
18POU3F2_20337985_ChIP-ChIP_501MEL_Human1.75866788
19SMAD_19615063_ChIP-ChIP_OVARY_Human1.75766811
20TRIM28_21343339_ChIP-Seq_HEK293_Human1.75639053
21PCGF2_27294783_Chip-Seq_NPCs_Mouse1.74591325
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73884300
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.72762265
24ZNF217_24962896_ChIP-Seq_MCF-7_Human1.72316897
25GATA1_26923725_Chip-Seq_HPCs_Mouse1.70377865
26TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.70089765
27TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.69925643
28POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.69925643
29P300_19829295_ChIP-Seq_ESCs_Human1.69748963
30RNF2_27304074_Chip-Seq_NSC_Mouse1.66167107
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.65635147
32NFE2_27457419_Chip-Seq_LIVER_Mouse1.65380347
33TAF15_26573619_Chip-Seq_HEK293_Human1.64464190
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62202897
35EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.62061226
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59827814
37CTNNB1_20460455_ChIP-Seq_HCT116_Human1.56893955
38NANOG_18555785_Chip-Seq_ESCs_Mouse1.56507668
39TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.56146626
40SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.55360845
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54274410
42VDR_22108803_ChIP-Seq_LS180_Human1.51827841
43DROSHA_22980978_ChIP-Seq_HELA_Human1.51818291
44P53_22387025_ChIP-Seq_ESCs_Mouse1.51375805
45FOXM1_26456572_ChIP-Seq_MCF-7_Human1.50166581
46ER_23166858_ChIP-Seq_MCF-7_Human1.49802684
47HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.48873309
48TAL1_26923725_Chip-Seq_HPCs_Mouse1.47073230
49STAT3_18555785_Chip-Seq_ESCs_Mouse1.46418516
50EZH2_27294783_Chip-Seq_ESCs_Mouse1.44622056
51CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43830404
52E2F1_18555785_Chip-Seq_ESCs_Mouse1.43345990
53SUZ12_18555785_Chip-Seq_ESCs_Mouse1.43112049
54EED_16625203_ChIP-ChIP_MESCs_Mouse1.42843997
55JARID2_20064375_ChIP-Seq_MESCs_Mouse1.41225245
56PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.40611918
57EZH2_27304074_Chip-Seq_ESCs_Mouse1.40554494
58REST_21632747_ChIP-Seq_MESCs_Mouse1.40156327
59SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.39986330
60SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.39634389
61SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.39335912
62TP53_16413492_ChIP-PET_HCT116_Human1.39049905
63FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.38997240
64EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.38355215
65CMYC_18555785_Chip-Seq_ESCs_Mouse1.37489717
66CTBP1_25329375_ChIP-Seq_LNCAP_Human1.37219696
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35870439
68NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35502856
69EZH2_27294783_Chip-Seq_NPCs_Mouse1.33917659
70SOX2_18555785_Chip-Seq_ESCs_Mouse1.33138621
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32577529
72SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.32458048
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.31667943
74TP53_18474530_ChIP-ChIP_U2OS_Human1.31571500
75SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.31500679
76SUZ12_27294783_Chip-Seq_ESCs_Mouse1.30948855
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.30625703
78TP63_23658742_ChIP-Seq_EP156T_Human1.30544915
79MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.29874810
80ETV1_20927104_ChIP-Seq_GIST48_Human1.29242956
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.29146294
82P300_18555785_Chip-Seq_ESCs_Mouse1.28483331
83OCT4_18555785_Chip-Seq_ESCs_Mouse1.28198549
84CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.28036432
85TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27599604
86NMYC_18555785_Chip-Seq_ESCs_Mouse1.26405379
87RUNX1_27457419_Chip-Seq_LIVER_Mouse1.26379659
88PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.25640631
89ZFX_18555785_Chip-Seq_ESCs_Mouse1.25471399
90* LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25236969
91MTF2_20144788_ChIP-Seq_MESCs_Mouse1.25081144
92MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24179409
93RNF2_27304074_Chip-Seq_ESCs_Mouse1.23625225
94PU1_27457419_Chip-Seq_LIVER_Mouse1.22771228
95FUS_26573619_Chip-Seq_HEK293_Human1.22469896
96PHF8_20622853_ChIP-Seq_HELA_Human1.22457144
97STAT3_23295773_ChIP-Seq_U87_Human1.21828078
98* TCF4_23295773_ChIP-Seq_U87_Human1.21594172
99CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.21586074
100JARID2_20075857_ChIP-Seq_MESCs_Mouse1.21173082
101EZH2_18974828_ChIP-Seq_MESCs_Mouse1.20214008
102RNF2_18974828_ChIP-Seq_MESCs_Mouse1.20214008
103CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19416018
104ARNT_22903824_ChIP-Seq_MCF-7_Human1.19054708
105SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.17909645
106* SMC4_20622854_ChIP-Seq_HELA_Human1.17588263
107HNFA_21074721_ChIP-Seq_CACO-2_Human1.17416525
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.17202399
109AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15723036
110TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.15472246
111KDM2B_26808549_Chip-Seq_REH_Human1.14702451
112ESRRB_18555785_Chip-Seq_ESCs_Mouse1.14068842
113TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13841105
114AHR_22903824_ChIP-Seq_MCF-7_Human1.12832607
115LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12090244
116CTCF_18555785_Chip-Seq_ESCs_Mouse1.11836879
117TBL1_22424771_ChIP-Seq_293T_Human1.11672307
118NFYA_21822215_ChIP-Seq_K562_Human1.11570470
119KLF4_18555785_Chip-Seq_ESCs_Mouse1.11222778
120EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10815175
121RUNX1_27514584_Chip-Seq_MCF-7_Human1.10780491
122AR_25329375_ChIP-Seq_VCAP_Human1.10550902
123* SMRT_27268052_Chip-Seq_Bcells_Human1.09450622
124SMAD3_21741376_ChIP-Seq_HESCs_Human1.08856517
125ESR2_21235772_ChIP-Seq_MCF-7_Human1.08742938
126CRX_20693478_ChIP-Seq_RETINA_Mouse1.08498606
127KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08427217
128UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08175382
129TCF4_22108803_ChIP-Seq_LS180_Human1.07584761
130IGF1R_20145208_ChIP-Seq_DFB_Human1.07482412
131RUNX2_22187159_ChIP-Seq_PCA_Human1.07427908
132* TP63_22573176_ChIP-Seq_HFKS_Human1.07314303
133SOX9_24532713_ChIP-Seq_HFSC_Mouse1.06920580
134MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.06867257
135KLF5_25053715_ChIP-Seq_YYC3_Human1.05821148
136NFYB_21822215_ChIP-Seq_K562_Human1.05583536
137AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.05013460
138* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02594776
139ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.02348878
140CBX2_22325352_ChIP-Seq_293T-Rex_Human1.01771886
141RBPJ_21746931_ChIP-Seq_IB4_Human1.01088095
142FOXA1_25552417_ChIP-Seq_VCAP_Human1.00645517
143EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00640352
144STAT1_20625510_ChIP-Seq_HELA_Human1.00446061
145CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00368879
146AR_19668381_ChIP-Seq_PC3_Human1.00075202
147P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99626888
148BCAT_22108803_ChIP-Seq_LS180_Human0.98739720
149SMAD4_21741376_ChIP-Seq_EPCs_Human0.95868188
150SMAD4_21741376_ChIP-Seq_HESCs_Human0.92910413
151GATA6_21074721_ChIP-Seq_CACO-2_Human0.92218954
152RAD21_21589869_ChIP-Seq_MESCs_Mouse0.92056828
153RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.91052466
154CBP_20019798_ChIP-Seq_JUKART_Human0.89984815
155IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89984815
156CTCF_27219007_Chip-Seq_Bcells_Human0.88765242
157YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88504282
158GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.88465304
159WDR5_24793694_ChIP-Seq_LNCAP_Human0.87416019

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction6.01416975
2MP0005410_abnormal_fertilization5.23291617
3MP0008875_abnormal_xenobiotic_pharmacok4.39079528
4MP0005646_abnormal_pituitary_gland3.87419453
5MP0003136_yellow_coat_color3.54205999
6MP0002282_abnormal_trachea_morphology3.07412238
7MP0000383_abnormal_hair_follicle2.65692551
8MP0001188_hyperpigmentation2.56141170
9MP0004043_abnormal_pH_regulation2.55827694
10MP0000566_synostosis2.54989878
11MP0002102_abnormal_ear_morphology2.42046021
12MP0009780_abnormal_chondrocyte_physiolo2.41677697
13MP0005670_abnormal_white_adipose2.37812050
14MP0002653_abnormal_ependyma_morphology2.20583725
15MP0003698_abnormal_male_reproductive2.14936625
16MP0005171_absent_coat_pigmentation2.14123880
17MP0010678_abnormal_skin_adnexa2.04522169
18MP0006292_abnormal_olfactory_placode2.02643576
19MP0003880_abnormal_central_pattern2.00992285
20MP0005623_abnormal_meninges_morphology1.94675556
21MP0002132_abnormal_respiratory_system1.89564388
22MP0008004_abnormal_stomach_pH1.84883230
23MP0002160_abnormal_reproductive_system1.81822945
24MP0001929_abnormal_gametogenesis1.80662574
25MP0005645_abnormal_hypothalamus_physiol1.76111978
26MP0002735_abnormal_chemical_nociception1.65560734
27MP0005377_hearing/vestibular/ear_phenot1.62968288
28MP0003878_abnormal_ear_physiology1.62968288
29MP0002638_abnormal_pupillary_reflex1.62760254
30MP0010030_abnormal_orbit_morphology1.62193303
31MP0005423_abnormal_somatic_nervous1.54124821
32MP0001486_abnormal_startle_reflex1.52838072
33MP0010386_abnormal_urinary_bladder1.51676486
34MP0008995_early_reproductive_senescence1.50702883
35MP0002572_abnormal_emotion/affect_behav1.50511118
36MP0009046_muscle_twitch1.49022579
37MP0001346_abnormal_lacrimal_gland1.47586240
38MP0004019_abnormal_vitamin_homeostasis1.46920555
39MP0004859_abnormal_synaptic_plasticity1.46578085
40MP0009745_abnormal_behavioral_response1.46495103
41MP0002876_abnormal_thyroid_physiology1.43273394
42MP0004133_heterotaxia1.41182432
43MP0003635_abnormal_synaptic_transmissio1.41146659
44MP0009697_abnormal_copulation1.40840403
45MP0004782_abnormal_surfactant_physiolog1.39829539
46MP0002928_abnormal_bile_duct1.39620124
47MP0001968_abnormal_touch/_nociception1.37684902
48MP0002063_abnormal_learning/memory/cond1.35364268
49MP0001485_abnormal_pinna_reflex1.35176380
50MP0002557_abnormal_social/conspecific_i1.34166335
51MP0002736_abnormal_nociception_after1.32640185
52MP0005647_abnormal_sex_gland1.30251639
53MP0001765_abnormal_ion_homeostasis1.27263511
54MP0008877_abnormal_DNA_methylation1.26868943
55MP0003646_muscle_fatigue1.26721910
56MP0002272_abnormal_nervous_system1.26335587
57MP0001502_abnormal_circadian_rhythm1.25775480
58MP0002210_abnormal_sex_determination1.24675178
59MP0001501_abnormal_sleep_pattern1.24543890
60MP0006276_abnormal_autonomic_nervous1.24391267
61MP0005389_reproductive_system_phenotype1.23450120
62MP0005083_abnormal_biliary_tract1.20694260
63MP0003787_abnormal_imprinting1.19911377
64MP0005551_abnormal_eye_electrophysiolog1.19371945
65MP0002168_other_aberrant_phenotype1.16440722
66MP0002909_abnormal_adrenal_gland1.15950197
67MP0001293_anophthalmia1.14669735
68MP0005084_abnormal_gallbladder_morpholo1.14327918
69MP0002734_abnormal_mechanical_nocicepti1.13846808
70MP0003656_abnormal_erythrocyte_physiolo1.11912653
71MP0000778_abnormal_nervous_system1.11502644
72MP0002161_abnormal_fertility/fecundity1.10424027
73MP0000026_abnormal_inner_ear1.09576535
74MP0003879_abnormal_hair_cell1.09022445
75MP0001986_abnormal_taste_sensitivity1.08892721
76MP0001440_abnormal_grooming_behavior1.06507846
77MP0003724_increased_susceptibility_to1.06493810
78MP0002822_catalepsy1.06024099
79MP0002064_seizures1.05515211
80MP0002067_abnormal_sensory_capabilities1.04439551
81MP0001905_abnormal_dopamine_level1.04256016
82MP0005409_darkened_coat_color1.02761061
83MP0000015_abnormal_ear_pigmentation1.01549164
84MP0002277_abnormal_respiratory_mucosa1.00987086
85MP0004742_abnormal_vestibular_system1.00325085
86MP0005503_abnormal_tendon_morphology0.99796720
87MP0002184_abnormal_innervation0.97666167
88MP0002127_abnormal_cardiovascular_syste0.96750056
89MP0003941_abnormal_skin_development0.96081049
90MP0002233_abnormal_nose_morphology0.95527569
91MP0004381_abnormal_hair_follicle0.94155863
92MP0005394_taste/olfaction_phenotype0.93567825
93MP0005499_abnormal_olfactory_system0.93567825
94MP0000631_abnormal_neuroendocrine_gland0.92174623
95MP0005253_abnormal_eye_physiology0.90774940
96MP0001963_abnormal_hearing_physiology0.90342957
97MP0005167_abnormal_blood-brain_barrier0.88973410
98MP0001970_abnormal_pain_threshold0.88799894
99MP0002752_abnormal_somatic_nervous0.88695877
100MP0008789_abnormal_olfactory_epithelium0.88142594
101MP0002249_abnormal_larynx_morphology0.86267185
102MP0001879_abnormal_lymphatic_vessel0.86215875
103MP0000653_abnormal_sex_gland0.86159199
104MP0004885_abnormal_endolymph0.84444655
105MP0001177_atelectasis0.82841363
106MP0000049_abnormal_middle_ear0.81024210
107MP0001919_abnormal_reproductive_system0.78611058
108MP0002133_abnormal_respiratory_system0.78468524
109MP0005388_respiratory_system_phenotype0.78468524
110MP0005365_abnormal_bile_salt0.78271541
111MP0002116_abnormal_craniofacial_bone0.77811538
112MP0000955_abnormal_spinal_cord0.77762138
113MP0003937_abnormal_limbs/digits/tail_de0.77720578
114MP0001145_abnormal_male_reproductive0.77558705
115MP0002229_neurodegeneration0.77487389
116MP0009250_abnormal_appendicular_skeleto0.77429183
117MP0005248_abnormal_Harderian_gland0.76891967
118MP0005636_abnormal_mineral_homeostasis0.76473407
119MP0001299_abnormal_eye_distance/0.75849926
120MP0009379_abnormal_foot_pigmentation0.75543720
121MP0003861_abnormal_nervous_system0.75420299
122MP0002938_white_spotting0.74245498
123MP0002882_abnormal_neuron_morphology0.73706120
124MP0004215_abnormal_myocardial_fiber0.73343068
125MP0005395_other_phenotype0.72887415
126MP0005165_increased_susceptibility_to0.72784194
127MP0004145_abnormal_muscle_electrophysio0.71998572
128MP0002295_abnormal_pulmonary_circulatio0.71312685
129MP0003718_maternal_effect0.71209869
130MP0005391_vision/eye_phenotype0.70422396
131MP0001324_abnormal_eye_pigmentation0.69764084
132MP0005195_abnormal_posterior_eye0.69311441
133MP0010368_abnormal_lymphatic_system0.68667920
134MP0005379_endocrine/exocrine_gland_phen0.66850265
135MP0003633_abnormal_nervous_system0.66332751
136MP0003938_abnormal_ear_development0.66194677
137MP0001529_abnormal_vocalization0.65826757
138MP0004270_analgesia0.64414711
139MP0000678_abnormal_parathyroid_gland0.64169033
140MP0001944_abnormal_pancreas_morphology0.63631310
141MP0001270_distended_abdomen0.63154136
142MP0003943_abnormal_hepatobiliary_system0.62987459
143MP0003942_abnormal_urinary_system0.62097042
144MP0009703_decreased_birth_body0.57303974
145MP0002152_abnormal_brain_morphology0.57286416
146MP0000465_gastrointestinal_hemorrhage0.54794627
147MP0002084_abnormal_developmental_patter0.52162713
148MP0003631_nervous_system_phenotype0.48361077
149MP0002092_abnormal_eye_morphology0.47311175
150MP0002136_abnormal_kidney_physiology0.47142449
151MP0005085_abnormal_gallbladder_physiolo0.47101066

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.88471543
2Dynein arm defect of respiratory motile cilia (HP:0012255)8.94427702
3Absent/shortened dynein arms (HP:0200106)8.94427702
4Abnormal respiratory motile cilium morphology (HP:0005938)8.78218154
5Abnormal respiratory epithelium morphology (HP:0012253)8.78218154
6Rhinitis (HP:0012384)8.35032100
7Chronic bronchitis (HP:0004469)6.16253763
8Bronchiectasis (HP:0002110)4.89901268
9Nephronophthisis (HP:0000090)3.92365598
10True hermaphroditism (HP:0010459)3.72961839
11Pancreatic fibrosis (HP:0100732)3.70891690
12Nasal polyposis (HP:0100582)3.62833764
13Tubulointerstitial nephritis (HP:0001970)3.34431102
14Recurrent sinusitis (HP:0011108)3.23358696
15Bronchitis (HP:0012387)3.22695290
16Chronic sinusitis (HP:0011109)3.20991039
17Infertility (HP:0000789)3.19882025
18Abnormality of midbrain morphology (HP:0002418)3.17813814
19Molar tooth sign on MRI (HP:0002419)3.17813814
20Chronic hepatic failure (HP:0100626)3.06746668
21Medial flaring of the eyebrow (HP:0010747)3.01650333
22Abnormality of the renal medulla (HP:0100957)3.01091095
23Abnormality of the nasal mucosa (HP:0000433)2.95506480
24Occipital encephalocele (HP:0002085)2.88361978
25Pancreatic cysts (HP:0001737)2.86661119
26Median cleft lip (HP:0000161)2.72953406
27Gait imbalance (HP:0002141)2.65201440
28Chronic otitis media (HP:0000389)2.62124001
29Congenital primary aphakia (HP:0007707)2.61648408
30Postaxial foot polydactyly (HP:0001830)2.59942125
31Congenital hepatic fibrosis (HP:0002612)2.57902056
32Abnormality of permanent molar morphology (HP:0011071)2.53921269
33Abnormality of the dental root (HP:0006486)2.53921269
34Taurodontia (HP:0000679)2.53921269
35Nephrogenic diabetes insipidus (HP:0009806)2.50424595
36Abnormality of molar (HP:0011077)2.50293765
37Abnormality of molar morphology (HP:0011070)2.50293765
38Retinal dysplasia (HP:0007973)2.42884097
39Cystic liver disease (HP:0006706)2.38712170
40Male infertility (HP:0003251)2.38447334
41Recurrent otitis media (HP:0000403)2.34765221
42Abnormality of the dental pulp (HP:0006479)2.29976969
43Abnormality of dentin (HP:0010299)2.27059212
44Abnormal biliary tract physiology (HP:0012439)2.15208216
45Bile duct proliferation (HP:0001408)2.15208216
46Supernumerary spleens (HP:0009799)2.13154138
47Postaxial hand polydactyly (HP:0001162)2.12310175
48Hyperactive renin-angiotensin system (HP:0000841)2.10818025
49Febrile seizures (HP:0002373)2.09813182
50Stage 5 chronic kidney disease (HP:0003774)2.08666601
51Poor coordination (HP:0002370)2.08043502
52Preaxial hand polydactyly (HP:0001177)2.03645013
53Male pseudohermaphroditism (HP:0000037)2.02722485
54Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.9567153
55Abnormal respiratory motile cilium physiology (HP:0012261)10.4800979
56Aplasia/Hypoplasia of the lens (HP:0008063)1.96453217
57Aplasia/Hypoplasia of the tongue (HP:0010295)1.95235367
58Tubulointerstitial abnormality (HP:0001969)1.94686347
59Genital tract atresia (HP:0001827)1.92019213
60Vaginal atresia (HP:0000148)1.87837894
61Hypothermia (HP:0002045)1.69861450
62Sclerocornea (HP:0000647)1.68741520
63Oculomotor apraxia (HP:0000657)1.67946719
64Nephropathy (HP:0000112)1.66837088
65Fibular hypoplasia (HP:0003038)1.66105585
66Abnormality of the renal cortex (HP:0011035)1.66000276
67Atelectasis (HP:0100750)1.65550878
68Bony spicule pigmentary retinopathy (HP:0007737)1.63300821
69Facial cleft (HP:0002006)1.59773780
70Tubular atrophy (HP:0000092)1.56612140
71Anencephaly (HP:0002323)1.56279750
72Bifid tongue (HP:0010297)1.54916888
73Absent rod-and cone-mediated responses on ERG (HP:0007688)1.54607773
74Chromosomal breakage induced by crosslinking agents (HP:0003221)1.53197504
75Absent frontal sinuses (HP:0002688)1.52690863
76Bell-shaped thorax (HP:0001591)1.50931610
77Asplenia (HP:0001746)1.50604530
78Hypotelorism (HP:0000601)1.48709624
79Focal motor seizures (HP:0011153)1.48645696
80Aplasia/Hypoplasia of the spleen (HP:0010451)1.47413800
81Atonic seizures (HP:0010819)1.45891177
82Decreased central vision (HP:0007663)1.43926606
83Aganglionic megacolon (HP:0002251)1.41123645
84Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.39688512
85Narrow forehead (HP:0000341)1.39085968
86Short nail (HP:0001799)1.35393281
87Retinitis pigmentosa (HP:0000510)1.35290738
88Alveolar cell carcinoma (HP:0006519)1.31624312
89Anophthalmia (HP:0000528)1.29067835
90Hip dysplasia (HP:0001385)1.28436818
91Aplasia/Hypoplasia of the tibia (HP:0005772)1.28298910
92Syncope (HP:0001279)1.28096991
93Decreased circulating renin level (HP:0003351)1.27714016
94Furrowed tongue (HP:0000221)1.27206012
95Atrial fibrillation (HP:0005110)1.27034178
96Recurrent bronchitis (HP:0002837)1.26989642
97Optic nerve hypoplasia (HP:0000609)1.26509953
98Renal salt wasting (HP:0000127)1.25801428
99Abnormal hair whorl (HP:0010721)1.25287529
100Neoplasm of the tracheobronchial system (HP:0100552)1.25148967
101Abnormal drinking behavior (HP:0030082)1.23993522
102Polydipsia (HP:0001959)1.23993522
103Hyperkalemia (HP:0002153)1.23831335
104Retrobulbar optic neuritis (HP:0100654)1.23418149
105Optic neuritis (HP:0100653)1.23418149
106Left ventricular hypertrophy (HP:0001712)1.23243102
107Hyperventilation (HP:0002883)1.23211178
108Specific learning disability (HP:0001328)1.23098497
109Bradycardia (HP:0001662)1.22835436
110Short thorax (HP:0010306)1.21505909
111Intellectual disability, moderate (HP:0002342)1.21024836
112Broad distal phalanx of finger (HP:0009836)1.20100267
113Optic nerve coloboma (HP:0000588)1.19851374
114Cone-rod dystrophy (HP:0000548)1.19550338
115Polyuria (HP:0000103)1.13917087
116Abnormal rod and cone electroretinograms (HP:0008323)1.13080056
117Hyperaldosteronism (HP:0000859)1.11664245
118Abnormality of the frontal sinuses (HP:0002687)1.11551262
119Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.09031323
120Tubulointerstitial fibrosis (HP:0005576)1.08987168
121Fetal akinesia sequence (HP:0001989)1.07067281
122Abnormality of renal excretion (HP:0011036)1.05181643
123Prominent nasal bridge (HP:0000426)1.03170560
124Portal hypertension (HP:0001409)1.00593108
125Abnormality of renin-angiotensin system (HP:0000847)1.00416056
126Highly arched eyebrow (HP:0002553)1.00352970
127Bifid scrotum (HP:0000048)0.99568254

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK154.24917933
2MST43.90488149
3CASK3.41302234
4EPHA23.01386497
5MAP2K73.00693802
6PDK22.81729736
7PDK42.52781970
8PDK32.52781970
9TSSK62.32230296
10ERBB32.20641166
11NTRK32.13059914
12INSRR2.07285817
13ZAK2.00365659
14PRKD31.95266892
15MUSK1.95147338
16MAPK131.94882982
17TNIK1.93604271
18PINK11.92874913
19PRPF4B1.89577841
20STK161.84277998
21STK38L1.77782677
22CDK31.70166608
23MKNK21.68239154
24IRAK31.63700797
25NEK61.61024003
26MAPKAPK31.57569325
27BMPR21.56040854
28NME11.50747232
29STK241.45305559
30MAP3K21.41922057
31PNCK1.39548858
32TIE11.37769198
33MAP3K41.37191122
34SGK21.34148288
35TRPM71.33142679
36TLK11.32674526
37NTRK21.32292406
38GRK11.31494073
39NUAK11.31216282
40IRAK21.30292342
41PTK2B1.30147094
42TESK11.28077511
43BRAF1.26701881
44AKT31.24516180
45TNK21.23347151
46PHKG11.21988012
47PHKG21.21988012
48MAP3K141.14594346
49ICK1.14468962
50TXK1.12151654
51WNK41.12033289
52CSK1.11474518
53IRAK11.09296916
54LMTK21.05346307
55ADRBK20.97530259
56EPHB10.97266743
57EPHA40.95840240
58MET0.93277760
59MAP3K70.93109606
60SIK30.92750723
61GRK70.90017247
62LRRK20.88745811
63SGK4940.88703120
64SGK2230.88703120
65MARK10.84971939
66PRKCG0.83722573
67PLK20.82243853
68PRKCE0.81679106
69STK380.80096488
70WEE10.79207993
71CAMKK10.78892590
72PRKCI0.78024769
73TTK0.77273652
74ERBB20.76907379
75CAMK2A0.76869161
76EEF2K0.76170704
77MAP3K120.75804397
78MARK20.75776223
79CAMK2D0.72619926
80MAPK70.71590668
81EPHA30.71415567
82YES10.71370674
83IRAK40.69990497
84CAMK2B0.69610991
85RPS6KA20.69390530
86OBSCN0.68653543
87PLK40.67675528
88DAPK20.67596587
89MYLK0.67572972
90MAP3K30.66747609
91DYRK1A0.63734285
92EIF2AK20.62298942
93MAPKAPK50.61955228
94SMG10.60935716
95SGK30.60154969
96ARAF0.57467815
97MST1R0.57095527
98BMPR1B0.55053284
99CAMK2G0.54193874
100PAK30.53853543
101BRSK20.51768354
102SGK10.51117647
103STK100.50468776
104MAPK120.50320850
105NEK90.50238748
106WNK10.50044381
107CDK80.49916564
108PKN10.49485447
109PRKG20.49423998
110DYRK1B0.49307493
111PRKG10.48993660
112NLK0.47396979
113LATS10.46658879
114PRKCH0.45594072
115VRK10.45320444
116BCR0.44044659
117PASK0.42358007
118PRKCQ0.40237091
119MKNK10.39981667
120MAP2K40.39651106
121PRKD20.38543049
122STK390.38491625
123PRKACA0.38369380
124TBK10.37379745
125STK110.37039010
126FRK0.36373626
127PIM20.35851541
128BMX0.35250270
129RIPK40.35246616
130PRKAA20.33508819
131PRKCD0.33380233
132GRK50.32789648
133ROCK10.32728558
134PRKAA10.32559959
135CAMK1G0.30313464
136PRKCZ0.30232189
137CAMK10.30204580
138CCNB10.29292174
139RET0.28990287
140PRKCA0.28458937
141MAPK100.28125866
142CDC42BPA0.27208701
143TEC0.26283768
144OXSR10.25034858
145FGR0.24640831
146RPS6KB10.24494048
147AURKA0.24072696
148PDPK10.21881153
149DYRK30.21258223
150TYK20.21220625
151MAP2K20.21061906
152CDK50.18549472
153RPS6KA50.17986706

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047405.21102032
2Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009804.63736044
3Histidine metabolism_Homo sapiens_hsa003403.98900044
4Phenylalanine metabolism_Homo sapiens_hsa003603.85533503
5Chemical carcinogenesis_Homo sapiens_hsa052043.81434343
6Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.78418610
7Tyrosine metabolism_Homo sapiens_hsa003502.95909229
8Nicotine addiction_Homo sapiens_hsa050332.71554748
9beta-Alanine metabolism_Homo sapiens_hsa004102.62468580
10Taste transduction_Homo sapiens_hsa047422.43526512
11Phototransduction_Homo sapiens_hsa047442.26842971
12Circadian entrainment_Homo sapiens_hsa047132.10937365
13Morphine addiction_Homo sapiens_hsa050322.06023615
14Caffeine metabolism_Homo sapiens_hsa002321.99961366
15Vitamin B6 metabolism_Homo sapiens_hsa007501.96654337
16Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.89831161
17Retinol metabolism_Homo sapiens_hsa008301.87105476
18Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.84354008
19Ovarian steroidogenesis_Homo sapiens_hsa049131.83980485
20Amphetamine addiction_Homo sapiens_hsa050311.80763023
21Glutathione metabolism_Homo sapiens_hsa004801.79633202
22ABC transporters_Homo sapiens_hsa020101.79455280
23Calcium signaling pathway_Homo sapiens_hsa040201.78924871
24Insulin secretion_Homo sapiens_hsa049111.78455666
25Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.73500170
26Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.71815183
27Glutamatergic synapse_Homo sapiens_hsa047241.71495652
28cAMP signaling pathway_Homo sapiens_hsa040241.56528169
29Huntingtons disease_Homo sapiens_hsa050161.52479795
30GABAergic synapse_Homo sapiens_hsa047271.46702971
31Tight junction_Homo sapiens_hsa045301.45939024
32Fanconi anemia pathway_Homo sapiens_hsa034601.42404490
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.39828243
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.39303470
35Salivary secretion_Homo sapiens_hsa049701.39230728
36Collecting duct acid secretion_Homo sapiens_hsa049661.33549459
37Purine metabolism_Homo sapiens_hsa002301.32665638
38Circadian rhythm_Homo sapiens_hsa047101.31697806
39Arachidonic acid metabolism_Homo sapiens_hsa005901.27947201
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.25460907
41Autoimmune thyroid disease_Homo sapiens_hsa053201.23659378
42Serotonergic synapse_Homo sapiens_hsa047261.21982597
43Renin secretion_Homo sapiens_hsa049241.21445139
44Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.17907456
45Aldosterone synthesis and secretion_Homo sapiens_hsa049251.17707377
46Steroid hormone biosynthesis_Homo sapiens_hsa001401.17303804
47cGMP-PKG signaling pathway_Homo sapiens_hsa040221.16507723
48Basal cell carcinoma_Homo sapiens_hsa052171.16371388
49Primary bile acid biosynthesis_Homo sapiens_hsa001201.12504109
50Sphingolipid metabolism_Homo sapiens_hsa006001.11801697
51Allograft rejection_Homo sapiens_hsa053301.11338565
52Notch signaling pathway_Homo sapiens_hsa043301.11190030
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.11174552
54Synaptic vesicle cycle_Homo sapiens_hsa047211.09881983
55SNARE interactions in vesicular transport_Homo sapiens_hsa041301.09047198
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.07085905
57Peroxisome_Homo sapiens_hsa041461.06171436
58Basal transcription factors_Homo sapiens_hsa030221.05860909
59Gastric acid secretion_Homo sapiens_hsa049711.05009986
60Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.04173470
61Fatty acid biosynthesis_Homo sapiens_hsa000611.01080620
62Rheumatoid arthritis_Homo sapiens_hsa053231.01017089
63Cholinergic synapse_Homo sapiens_hsa047250.99856359
64Graft-versus-host disease_Homo sapiens_hsa053320.98084141
65Cardiac muscle contraction_Homo sapiens_hsa042600.96697600
66Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.95281380
67Cocaine addiction_Homo sapiens_hsa050300.92223047
68Ether lipid metabolism_Homo sapiens_hsa005650.91746222
69Vitamin digestion and absorption_Homo sapiens_hsa049770.91192013
70Dilated cardiomyopathy_Homo sapiens_hsa054140.90261009
71Systemic lupus erythematosus_Homo sapiens_hsa053220.89568092
72Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.89298483
73Dopaminergic synapse_Homo sapiens_hsa047280.88853120
74Fatty acid degradation_Homo sapiens_hsa000710.88800501
75Long-term potentiation_Homo sapiens_hsa047200.85050500
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.84941128
77Other glycan degradation_Homo sapiens_hsa005110.84833210
78Alcoholism_Homo sapiens_hsa050340.84363649
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.82420150
80Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81906509
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80252234
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79964163
83Oxytocin signaling pathway_Homo sapiens_hsa049210.77749668
84Hippo signaling pathway_Homo sapiens_hsa043900.76948046
85Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.76867030
86Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76819808
87Starch and sucrose metabolism_Homo sapiens_hsa005000.73873628
88Estrogen signaling pathway_Homo sapiens_hsa049150.72252637
89Hematopoietic cell lineage_Homo sapiens_hsa046400.72202260
90Linoleic acid metabolism_Homo sapiens_hsa005910.71408683
91Bile secretion_Homo sapiens_hsa049760.70811755
92Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69262991
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.68960777
94Mineral absorption_Homo sapiens_hsa049780.66713584
95GnRH signaling pathway_Homo sapiens_hsa049120.65620176
96alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65534593
97Oxidative phosphorylation_Homo sapiens_hsa001900.63410975
98Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.63253965
99Type I diabetes mellitus_Homo sapiens_hsa049400.63114112
100Inositol phosphate metabolism_Homo sapiens_hsa005620.61745982
101Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61134321
102Choline metabolism in cancer_Homo sapiens_hsa052310.60785409
103Melanogenesis_Homo sapiens_hsa049160.59971318
104Ras signaling pathway_Homo sapiens_hsa040140.59158465
105Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58856058
106Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58494334
107Vibrio cholerae infection_Homo sapiens_hsa051100.58458811
108Glycerophospholipid metabolism_Homo sapiens_hsa005640.56363138
109Axon guidance_Homo sapiens_hsa043600.56085993
110Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.56007622
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.55806324
112Glucagon signaling pathway_Homo sapiens_hsa049220.55711581
113Wnt signaling pathway_Homo sapiens_hsa043100.55636804
114Thyroid hormone synthesis_Homo sapiens_hsa049180.55024951
115Leukocyte transendothelial migration_Homo sapiens_hsa046700.54442361
116Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53562820
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.52837184
118Dorso-ventral axis formation_Homo sapiens_hsa043200.52291657
119Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51489776
120Asthma_Homo sapiens_hsa053100.51077081
121Alzheimers disease_Homo sapiens_hsa050100.50336883
122Adherens junction_Homo sapiens_hsa045200.48893348
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.47940251
124Nitrogen metabolism_Homo sapiens_hsa009100.47189923
125Intestinal immune network for IgA production_Homo sapiens_hsa046720.45888922
126PPAR signaling pathway_Homo sapiens_hsa033200.43086744
127Type II diabetes mellitus_Homo sapiens_hsa049300.41938009
128Pancreatic secretion_Homo sapiens_hsa049720.41391214
129Phagosome_Homo sapiens_hsa041450.39728914
130Complement and coagulation cascades_Homo sapiens_hsa046100.38333892
131MAPK signaling pathway_Homo sapiens_hsa040100.36531881
132Malaria_Homo sapiens_hsa051440.35509367
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34423937
134Pentose and glucuronate interconversions_Homo sapiens_hsa000400.33934260
135Butanoate metabolism_Homo sapiens_hsa006500.33080703
136Parkinsons disease_Homo sapiens_hsa050120.30428302
137Hedgehog signaling pathway_Homo sapiens_hsa043400.29232564
138Hepatitis C_Homo sapiens_hsa051600.28822853
139Drug metabolism - other enzymes_Homo sapiens_hsa009830.28799183
140Pyrimidine metabolism_Homo sapiens_hsa002400.28521680
141Rap1 signaling pathway_Homo sapiens_hsa040150.27286006
142African trypanosomiasis_Homo sapiens_hsa051430.26799612
143Tryptophan metabolism_Homo sapiens_hsa003800.26637234
144Arginine and proline metabolism_Homo sapiens_hsa003300.26412103
145Gap junction_Homo sapiens_hsa045400.25919891
146Metabolic pathways_Homo sapiens_hsa011000.23925825

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »