VWA3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.89027832
2axonemal dynein complex assembly (GO:0070286)9.84893848
3epithelial cilium movement (GO:0003351)9.83287792
4binding of sperm to zona pellucida (GO:0007339)9.58101544
5cell-cell recognition (GO:0009988)9.56437052
6motile cilium assembly (GO:0044458)9.04280426
7reproduction (GO:0000003)8.83646717
8spermatid development (GO:0007286)8.77968081
9regulation of cilium movement (GO:0003352)8.59274019
10cilium movement (GO:0003341)8.55147109
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.99097459
12piRNA metabolic process (GO:0034587)7.08867787
13single fertilization (GO:0007338)7.04954513
14male meiosis (GO:0007140)7.04201383
15left/right axis specification (GO:0070986)7.03433395
16synaptonemal complex organization (GO:0070193)6.85935972
17synaptonemal complex assembly (GO:0007130)6.64845964
18microtubule bundle formation (GO:0001578)6.56961385
19primary alcohol catabolic process (GO:0034310)6.53334051
20microtubule depolymerization (GO:0007019)6.34492717
21sperm capacitation (GO:0048240)6.14680911
22fertilization (GO:0009566)5.98644466
23spermatogenesis (GO:0007283)5.93238508
24male gamete generation (GO:0048232)5.91382805
25negative regulation of inclusion body assembly (GO:0090084)5.83424650
26vitamin transmembrane transport (GO:0035461)5.73016101
27ethanol metabolic process (GO:0006067)5.50445561
28ventricular system development (GO:0021591)5.44829486
29gamete generation (GO:0007276)5.44660112
30organic cation transport (GO:0015695)5.21675147
31diterpenoid biosynthetic process (GO:0016102)5.04765395
32regulation of inclusion body assembly (GO:0090083)5.01933993
33germ cell development (GO:0007281)5.00723720
34regulation of microtubule-based movement (GO:0060632)5.00530906
35cellular process involved in reproduction in multicellular organism (GO:0022412)4.96967761
36DNA methylation involved in gamete generation (GO:0043046)4.91162653
37one-carbon compound transport (GO:0019755)4.90545962
38calcium ion-dependent exocytosis (GO:0017156)4.88772518
39response to xenobiotic stimulus (GO:0009410)4.73321614
40chromosome organization involved in meiosis (GO:0070192)4.70950478
41male meiosis I (GO:0007141)4.69791534
42glomerular epithelial cell development (GO:0072310)4.69650774
43cell recognition (GO:0008037)4.59535627
44spermatid nucleus differentiation (GO:0007289)4.55268778
45pyrimidine-containing compound transmembrane transport (GO:0072531)4.55146292
46regulation of interleukin-5 production (GO:0032674)4.53899009
47meiotic nuclear division (GO:0007126)4.45420454
48cell projection assembly (GO:0030031)4.34265743
49multicellular organismal reproductive process (GO:0048609)4.26213895
50regulation of interleukin-13 production (GO:0032656)4.25583995
51establishment of apical/basal cell polarity (GO:0035089)4.24144986
52chaperone-mediated protein complex assembly (GO:0051131)4.22801499
53lung epithelium development (GO:0060428)4.22481595
54microtubule severing (GO:0051013)4.22448630
55ethanol oxidation (GO:0006069)4.21591600
56chromosome condensation (GO:0030261)4.16891281
57tolerance induction (GO:0002507)4.15544518
58negative regulation of T cell differentiation in thymus (GO:0033085)4.14859601
59DNA packaging (GO:0006323)4.04111407
60protein polyglutamylation (GO:0018095)4.03851552
61glycerol ether metabolic process (GO:0006662)4.02519403
62axoneme assembly (GO:0035082)3.96570287
63sequestering of actin monomers (GO:0042989)3.96337911
64negative regulation of immunoglobulin mediated immune response (GO:0002890)3.96271193
65negative regulation of B cell mediated immunity (GO:0002713)3.96271193
66lateral ventricle development (GO:0021670)3.90449940
67meiosis I (GO:0007127)3.87383665
68establishment or maintenance of monopolar cell polarity (GO:0061339)3.86368284
69establishment of monopolar cell polarity (GO:0061162)3.86368284
70seminiferous tubule development (GO:0072520)3.75780033
71nucleoside diphosphate phosphorylation (GO:0006165)3.72975793
72protein localization to cilium (GO:0061512)3.72360553
73terpenoid biosynthetic process (GO:0016114)3.71375342
74ether metabolic process (GO:0018904)3.69960934
75single strand break repair (GO:0000012)3.68385362
76negative regulation of humoral immune response (GO:0002921)3.68097397
77retinoic acid metabolic process (GO:0042573)3.65843024
78cytoplasmic microtubule organization (GO:0031122)3.62954065
79left/right pattern formation (GO:0060972)3.53166967
80regulation of germinal center formation (GO:0002634)3.51774264
81meiotic cell cycle (GO:0051321)3.46253692
82negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.44477241
83establishment of planar polarity (GO:0001736)3.41758969
84establishment of tissue polarity (GO:0007164)3.41758969
85phosphatidylethanolamine biosynthetic process (GO:0006646)3.40450421
86microtubule polymerization or depolymerization (GO:0031109)3.38115469
87intraciliary transport (GO:0042073)3.37845960
88positive regulation of tolerance induction (GO:0002645)3.37581606
89multicellular organismal development (GO:0007275)3.37108006
90monoubiquitinated protein deubiquitination (GO:0035520)3.36083068
91retinal rod cell development (GO:0046548)3.32650771
92GTP biosynthetic process (GO:0006183)3.30291422
93regulation of spindle checkpoint (GO:0090231)3.28793439
94cilium organization (GO:0044782)3.22872499
95exogenous drug catabolic process (GO:0042738)3.15261248
96phosphatidylethanolamine metabolic process (GO:0046337)3.13267070
97cilium assembly (GO:0042384)3.12636874
98nucleus organization (GO:0006997)3.10602401
99protein refolding (GO:0042026)3.07248273
100UTP biosynthetic process (GO:0006228)3.06595655
101determination of left/right symmetry (GO:0007368)3.05059126
102regulation of centriole replication (GO:0046599)3.04522265
103microtubule-based movement (GO:0007018)3.03828863
104centriole assembly (GO:0098534)3.02090444
105retinol metabolic process (GO:0042572)3.01539139
106meiotic cell cycle process (GO:1903046)3.00622594
107cilium morphogenesis (GO:0060271)2.96394467
108primary alcohol metabolic process (GO:0034308)2.95092713
109synapsis (GO:0007129)2.94840107
110polyol catabolic process (GO:0046174)2.94556819
111cellular component assembly involved in morphogenesis (GO:0010927)2.94427486
112glutathione derivative biosynthetic process (GO:1901687)2.93823726
113glutathione derivative metabolic process (GO:1901685)2.93823726
114microtubule-based process (GO:0007017)2.93462992
115smoothened signaling pathway (GO:0007224)2.92624083
116determination of bilateral symmetry (GO:0009855)2.91839860
117protein K11-linked deubiquitination (GO:0035871)2.90583405
118positive regulation of smoothened signaling pathway (GO:0045880)2.89609006
119O-glycan processing (GO:0016266)2.88681270
120lateral sprouting from an epithelium (GO:0060601)2.86876076
121glycolytic process (GO:0006096)2.84975628
122specification of symmetry (GO:0009799)2.84875959
123gene silencing by RNA (GO:0031047)2.84370563
124photoreceptor cell maintenance (GO:0045494)2.84190741
125nuclear pore complex assembly (GO:0051292)2.82012812
126organelle assembly (GO:0070925)2.81256916
127regulation of chromatin binding (GO:0035561)2.80237730
128sexual reproduction (GO:0019953)2.79275024
129genitalia morphogenesis (GO:0035112)2.78560204
130UTP metabolic process (GO:0046051)2.77322054
131regulation of meiosis I (GO:0060631)2.74157978
132phosphatidylcholine biosynthetic process (GO:0006656)2.73904008
133retinal cone cell development (GO:0046549)2.73691353
134centriole replication (GO:0007099)2.70616995
135amino-acid betaine transport (GO:0015838)2.67075093
136carnitine transport (GO:0015879)2.67075093
137negative regulation of organelle assembly (GO:1902116)2.63973203
138interferon-gamma secretion (GO:0072643)2.63577176
139aldehyde catabolic process (GO:0046185)2.63037398
140mitotic sister chromatid cohesion (GO:0007064)2.61583337
141excretion (GO:0007588)2.61234822
142guanosine-containing compound biosynthetic process (GO:1901070)2.60453032
143alditol metabolic process (GO:0019400)2.59590639
144lactate metabolic process (GO:0006089)2.57073670
145regulation of microtubule depolymerization (GO:0031114)2.56129843
146carnitine transmembrane transport (GO:1902603)2.56063533
147nonmotile primary cilium assembly (GO:0035058)2.55984115
148regulation of cilium assembly (GO:1902017)2.54084948
149carnitine metabolic process (GO:0009437)2.49719117
150drug catabolic process (GO:0042737)2.49436092
151apical protein localization (GO:0045176)2.47046634
152intra-S DNA damage checkpoint (GO:0031573)2.45826438
153fusion of sperm to egg plasma membrane (GO:0007342)13.0061970
154cell wall macromolecule catabolic process (GO:0016998)12.5777481
155cell wall macromolecule metabolic process (GO:0044036)12.5777481
156sperm motility (GO:0030317)11.7842411
157cilium or flagellum-dependent cell motility (GO:0001539)10.9242659
158sperm-egg recognition (GO:0035036)10.7308882
159multicellular organism reproduction (GO:0032504)10.5632434
160acrosome assembly (GO:0001675)10.4721216
161acrosome reaction (GO:0007340)10.4178595

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.98822606
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.24265628
3EZH2_22144423_ChIP-Seq_EOC_Human4.05132674
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.73412291
5DROSHA_22980978_ChIP-Seq_HELA_Human3.31646752
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.92466727
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.57503940
8* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.57323409
9VDR_22108803_ChIP-Seq_LS180_Human2.45395908
10CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.36279956
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.25023969
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.21025679
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.04379693
14PIAS1_25552417_ChIP-Seq_VCAP_Human2.03823133
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.00628917
16KAP1_22055183_ChIP-Seq_ESCs_Mouse1.96331037
17ARNT_22903824_ChIP-Seq_MCF-7_Human1.94795481
18AHR_22903824_ChIP-Seq_MCF-7_Human1.92743033
19PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88536045
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.77773449
21ELK4_26923725_Chip-Seq_MESODERM_Mouse1.73640191
22NR3C1_21868756_ChIP-Seq_MCF10A_Human1.70671703
23ZNF274_21170338_ChIP-Seq_K562_Hela1.69439259
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66117761
25SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.65041432
26GATA3_21867929_ChIP-Seq_CD8_Mouse1.63788076
27TOP2B_26459242_ChIP-Seq_MCF-7_Human1.63424914
28ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.62716087
29KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.62298338
30AR_21572438_ChIP-Seq_LNCaP_Human1.61616120
31RBPJ_22232070_ChIP-Seq_NCS_Mouse1.61299958
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60151716
33TP63_23658742_ChIP-Seq_EP156T_Human1.60027331
34WDR5_24793694_ChIP-Seq_LNCAP_Human1.59997978
35FOXM1_26456572_ChIP-Seq_MCF-7_Human1.59116570
36SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.58883270
37STAT1_17558387_ChIP-Seq_HELA_Human1.57975430
38SOX2_22085726_ChIP-Seq_NPCs_Mouse1.57700109
39TP53_18474530_ChIP-ChIP_U2OS_Human1.57369612
40NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.55144639
41SMAD4_21799915_ChIP-Seq_A2780_Human1.54660418
42FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54288544
43TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.51660659
44TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.51486506
45EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.51446518
46* ETV1_20927104_ChIP-Seq_GIST48_Human1.50899478
47TDRD3_21172665_ChIP-Seq_MCF-7_Human1.50263857
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49251990
49ESR1_20079471_ChIP-ChIP_T-47D_Human1.48426409
50GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48008000
51SMC4_20622854_ChIP-Seq_HELA_Human1.45434149
52TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.44059132
53TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43668974
54POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.43668974
55PHF8_20622853_ChIP-Seq_HELA_Human1.42623488
56CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.42351589
57STAT6_21828071_ChIP-Seq_BEAS2B_Human1.42293597
58HNFA_21074721_ChIP-Seq_CACO-2_Human1.41885366
59* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.41612717
60GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.40741165
61* PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.40632953
62AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.39410672
63* SMRT_27268052_Chip-Seq_Bcells_Human1.39006986
64SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38615474
65RUNX1_27514584_Chip-Seq_MCF-7_Human1.38346286
66STAT1_20625510_ChIP-Seq_HELA_Human1.37149139
67GATA3_21867929_ChIP-Seq_TH1_Mouse1.36445940
68MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.34142375
69LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.33689854
70FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.32765701
71ER_23166858_ChIP-Seq_MCF-7_Human1.32539198
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.32273348
73PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32118878
74SMAD4_21741376_ChIP-Seq_EPCs_Human1.31254837
75TAL1_26923725_Chip-Seq_HPCs_Mouse1.30611351
76* RBPJ_21746931_ChIP-Seq_IB4_Human1.30278949
77RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.29534541
78KDM2B_26808549_Chip-Seq_REH_Human1.28231807
79NFE2_27457419_Chip-Seq_LIVER_Mouse1.28003522
80* CBX2_22325352_ChIP-Seq_293T-Rex_Human1.26094201
81FUS_26573619_Chip-Seq_HEK293_Human1.25879440
82* TP63_22573176_ChIP-Seq_HFKS_Human1.25508037
83ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.25121711
84NFYA_21822215_ChIP-Seq_K562_Human1.24887920
85* STAT3_23295773_ChIP-Seq_U87_Human1.24514790
86* KLF5_25053715_ChIP-Seq_YYC3_Human1.23102571
87CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23088286
88CTNNB1_20460455_ChIP-Seq_HCT116_Human1.22972734
89NFYB_21822215_ChIP-Seq_K562_Human1.22277312
90SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.21776850
91TBL1_22424771_ChIP-Seq_293T_Human1.21518547
92PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.20795957
93AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19356300
94YY1_22570637_ChIP-Seq_MALME-3M_Human1.18429542
95SUZ12_27294783_Chip-Seq_NPCs_Mouse1.16606726
96RARA_24833708_ChIP-Seq_LIVER_Mouse1.16025790
97RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.15757319
98SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.14775821
99ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14612969
100GATA6_21074721_ChIP-Seq_CACO-2_Human1.14501182
101VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.14381217
102BCAT_22108803_ChIP-Seq_LS180_Human1.14329696
103SPI1_26923725_Chip-Seq_HPCs_Mouse1.13694478
104REST_21632747_ChIP-Seq_MESCs_Mouse1.13262155
105TCF4_22108803_ChIP-Seq_LS180_Human1.12605682
106FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12501610
107FOXA1_25329375_ChIP-Seq_VCAP_Human1.12501610
108CBX2_27304074_Chip-Seq_ESCs_Mouse1.11868225
109RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.11798760
110PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.11589072
111STAT3_18555785_ChIP-Seq_MESCs_Mouse1.10233741
112* CEBPB_22108803_ChIP-Seq_LS180_Human1.09913656
113CTCF_20526341_ChIP-Seq_ESCs_Human1.09660264
114PHF8_20622854_ChIP-Seq_HELA_Human1.09183271
115SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.09078569
116* P53_21459846_ChIP-Seq_SAOS-2_Human1.08922306
117SOX2_27498859_Chip-Seq_STOMACH_Mouse1.08451005
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08389771
119TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.08306440
120* RUNX2_22187159_ChIP-Seq_PCA_Human1.07172520
121GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.06907657
122P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06570329
123FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.06371860
124TAF15_26573619_Chip-Seq_HEK293_Human1.06329278
125EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06147914
126FLI1_21867929_ChIP-Seq_CD8_Mouse1.05943969
127RUNX1_26923725_Chip-Seq_HPCs_Mouse1.05748288
128TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05478207
129MYC_19829295_ChIP-Seq_ESCs_Human1.05217165
130TCF4_23295773_ChIP-Seq_U87_Human1.05103056
131OCT4_20526341_ChIP-Seq_ESCs_Human1.05062516
132CTCF_27219007_Chip-Seq_Bcells_Human1.04960061
133* FOXA1_25552417_ChIP-Seq_VCAP_Human1.04245713
134AR_25329375_ChIP-Seq_VCAP_Human1.03742895
135CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03581545
136CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03328798
137RXRA_24833708_ChIP-Seq_LIVER_Mouse1.02004599
138RAD21_21589869_ChIP-Seq_MESCs_Mouse1.01837979
139IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01633970
140CBP_20019798_ChIP-Seq_JUKART_Human1.01633970
141CRX_20693478_ChIP-Seq_RETINA_Mouse1.01304269
142FLI1_21867929_ChIP-Seq_TH2_Mouse1.01154249
143SOX9_24532713_ChIP-Seq_HFSC_Mouse1.01096612
144* SMAD4_21741376_ChIP-Seq_HESCs_Human1.01061866
145P300_19829295_ChIP-Seq_ESCs_Human1.00532091
146SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99505936
147PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98146174
148MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.97941369
149OCT4_18555785_Chip-Seq_ESCs_Mouse0.96853311
150SMAD3_21741376_ChIP-Seq_ESCs_Human0.96434873
151EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.95430461
152LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.94883686
153AR_20517297_ChIP-Seq_VCAP_Human0.94710046
154ELF1_20517297_ChIP-Seq_JURKAT_Human0.94699140
155MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.93903840
156GF1_26923725_Chip-Seq_HPCs_Mouse0.93858686
157GATA4_25053715_ChIP-Seq_YYC3_Human0.93175707
158EZH2_27294783_Chip-Seq_ESCs_Mouse0.93075639
159ESET_19884257_ChIP-Seq_ESCs_Mouse0.93018072
160NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.92952631
161TET1_21451524_ChIP-Seq_MESCs_Mouse0.91701531
162ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90328042
163JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.89425863
164NANOG_18555785_Chip-Seq_ESCs_Mouse0.88490880
165KLF4_18555785_Chip-Seq_ESCs_Mouse0.88390461
166CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88164264
167PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.87191023
168P300_18555785_Chip-Seq_ESCs_Mouse0.86868775
169ESRRB_18555785_Chip-Seq_ESCs_Mouse0.86275933
170NANOG_20526341_ChIP-Seq_ESCs_Human0.85912500
171SOX11_22085726_ChIP-Seq_ESNs_Mouse0.85183535
172ERG_20517297_ChIP-Seq_VCAP_Human0.84646285
173SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84183725
174CMYC_18555785_Chip-Seq_ESCs_Mouse0.83361603
175TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82875678
176EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.82789266
177OCT4_21477851_ChIP-Seq_ESCs_Mouse0.82726853
178P53_22387025_ChIP-Seq_ESCs_Mouse0.82389439
179SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82380743
180RNF2_27304074_Chip-Seq_NSC_Mouse0.82086260
181SOX9_26525672_Chip-Seq_HEART_Mouse0.81735456

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok6.31156375
2MP0003698_abnormal_male_reproductive5.59865501
3MP0001929_abnormal_gametogenesis5.20848693
4MP0008877_abnormal_DNA_methylation4.82466009
5MP0002653_abnormal_ependyma_morphology3.81897074
6MP0002210_abnormal_sex_determination3.58107472
7MP0004043_abnormal_pH_regulation3.40772054
8MP0002277_abnormal_respiratory_mucosa3.21533097
9MP0002161_abnormal_fertility/fecundity3.11831633
10MP0009780_abnormal_chondrocyte_physiolo3.09714502
11MP0001145_abnormal_male_reproductive3.00441481
12MP0005670_abnormal_white_adipose2.83157444
13MP0000653_abnormal_sex_gland2.60047922
14MP0000566_synostosis2.37091527
15MP0001984_abnormal_olfaction2.27286913
16MP0002160_abnormal_reproductive_system2.27219555
17MP0000383_abnormal_hair_follicle2.10009252
18MP0002168_other_aberrant_phenotype2.00526446
19MP0005410_abnormal_fertilization14.2632488
20MP0008058_abnormal_DNA_repair1.86399808
21MP0005083_abnormal_biliary_tract1.83963300
22MP0000678_abnormal_parathyroid_gland1.73880494
23MP0005623_abnormal_meninges_morphology1.72645325
24MP0005248_abnormal_Harderian_gland1.69542267
25MP0010678_abnormal_skin_adnexa1.65835193
26MP0005395_other_phenotype1.61922842
27MP0004233_abnormal_muscle_weight1.55927659
28MP0010094_abnormal_chromosome_stability1.54693530
29MP0003646_muscle_fatigue1.49643719
30MP0008057_abnormal_DNA_replication1.48476452
31MP0001346_abnormal_lacrimal_gland1.45067173
32MP0002734_abnormal_mechanical_nocicepti1.41233000
33MP0003111_abnormal_nucleus_morphology1.40684135
34MP0003806_abnormal_nucleotide_metabolis1.40679231
35MP0002249_abnormal_larynx_morphology1.38941013
36MP0003878_abnormal_ear_physiology1.35540444
37MP0005377_hearing/vestibular/ear_phenot1.35540444
38MP0005389_reproductive_system_phenotype1.33107170
39MP0003656_abnormal_erythrocyte_physiolo1.31444593
40MP0003693_abnormal_embryo_hatching1.27751864
41MP0004133_heterotaxia1.27148756
42MP0002102_abnormal_ear_morphology1.15923682
43MP0002282_abnormal_trachea_morphology1.04014223
44MP0002909_abnormal_adrenal_gland1.01451735
45MP0000026_abnormal_inner_ear1.01185114
46MP0002638_abnormal_pupillary_reflex0.92879246
47MP0005394_taste/olfaction_phenotype0.92835288
48MP0005499_abnormal_olfactory_system0.92835288
49MP0001486_abnormal_startle_reflex0.92161044
50MP0001293_anophthalmia0.91027267
51MP0008789_abnormal_olfactory_epithelium0.90031484
52MP0003077_abnormal_cell_cycle0.89975446
53MP0009046_muscle_twitch0.89572518
54MP0002233_abnormal_nose_morphology0.88897601
55MP0001963_abnormal_hearing_physiology0.88689863
56MP0004957_abnormal_blastocyst_morpholog0.88199819
57MP0005310_abnormal_salivary_gland0.87167619
58MP0003786_premature_aging0.87112023
59MP0005165_increased_susceptibility_to0.86044439
60MP0002229_neurodegeneration0.82863795
61MP0008995_early_reproductive_senescence0.81471339
62MP0001730_embryonic_growth_arrest0.79176829
63MP0001765_abnormal_ion_homeostasis0.78993287
64MP0001970_abnormal_pain_threshold0.77819518
65MP0008932_abnormal_embryonic_tissue0.75562385
66MP0002876_abnormal_thyroid_physiology0.74306407
67MP0003787_abnormal_imprinting0.73915019
68MP0002269_muscular_atrophy0.73778573
69MP0005085_abnormal_gallbladder_physiolo0.72792102
70MP0002234_abnormal_pharynx_morphology0.71602827
71MP0005647_abnormal_sex_gland0.71140095
72MP0003011_delayed_dark_adaptation0.69888674
73MP0009643_abnormal_urine_homeostasis0.68115988
74MP0005408_hypopigmentation0.66629610
75MP0000681_abnormal_thyroid_gland0.66411763
76MP0005195_abnormal_posterior_eye0.66395009
77MP0002136_abnormal_kidney_physiology0.66108037
78MP0005365_abnormal_bile_salt0.65912165
79MP0005220_abnormal_exocrine_pancreas0.64299850
80MP0000465_gastrointestinal_hemorrhage0.62470873
81MP0009765_abnormal_xenobiotic_induced0.61086816
82MP0001119_abnormal_female_reproductive0.60614136
83MP0000955_abnormal_spinal_cord0.60103115
84MP0008007_abnormal_cellular_replicative0.59953028
85MP0003890_abnormal_embryonic-extraembry0.59913685
86MP0000358_abnormal_cell_content/0.59231082
87MP0006036_abnormal_mitochondrial_physio0.58490730
88MP0005646_abnormal_pituitary_gland0.57823218
89MP0000049_abnormal_middle_ear0.57334294
90MP0003937_abnormal_limbs/digits/tail_de0.56932070
91MP0003861_abnormal_nervous_system0.56660349
92MP0010307_abnormal_tumor_latency0.56055488
93MP0006035_abnormal_mitochondrial_morpho0.55799664
94MP0003699_abnormal_female_reproductive0.55453832
95MP0001879_abnormal_lymphatic_vessel0.55367758
96MP0002084_abnormal_developmental_patter0.54930167
97MP0002822_catalepsy0.54639634
98MP0001270_distended_abdomen0.53979222
99MP0003136_yellow_coat_color0.53027318
100MP0002557_abnormal_social/conspecific_i0.53026215
101MP0005164_abnormal_response_to0.51553522
102MP0000631_abnormal_neuroendocrine_gland0.50925806
103MP0002098_abnormal_vibrissa_morphology0.50667092
104MP0002736_abnormal_nociception_after0.50247126
105MP0009745_abnormal_behavioral_response0.50114096
106MP0003195_calcinosis0.49512115
107MP0008872_abnormal_physiological_respon0.49110568
108MP0002572_abnormal_emotion/affect_behav0.48844854
109MP0002139_abnormal_hepatobiliary_system0.48380769
110MP0003950_abnormal_plasma_membrane0.48379749
111MP0001666_abnormal_nutrient_absorption0.47355264
112MP0002085_abnormal_embryonic_tissue0.45180754
113MP0010030_abnormal_orbit_morphology0.44914410
114MP0010155_abnormal_intestine_physiology0.44815007
115MP0005380_embryogenesis_phenotype0.44665652
116MP0001672_abnormal_embryogenesis/_devel0.44665652
117MP0002928_abnormal_bile_duct0.43833074
118MP0003633_abnormal_nervous_system0.42979211
119MP0000313_abnormal_cell_death0.42854519
120MP0002116_abnormal_craniofacial_bone0.42487047
121MP0000467_abnormal_esophagus_morphology0.41236407
122MP0001944_abnormal_pancreas_morphology0.41043228
123MP0005666_abnormal_adipose_tissue0.39228900
124MP0003123_paternal_imprinting0.39186607
125MP0002080_prenatal_lethality0.37995304
126MP0002152_abnormal_brain_morphology0.37538664
127MP0005551_abnormal_eye_electrophysiolog0.37019945
128MP0000350_abnormal_cell_proliferation0.36984421
129MP0001697_abnormal_embryo_size0.36906255
130MP0001324_abnormal_eye_pigmentation0.36765088
131MP0005636_abnormal_mineral_homeostasis0.33634936
132MP0001968_abnormal_touch/_nociception0.33210939
133MP0003879_abnormal_hair_cell0.33089875
134MP0001919_abnormal_reproductive_system0.32789724
135MP0005391_vision/eye_phenotype0.32665664
136MP0004036_abnormal_muscle_relaxation0.32550957
137MP0001764_abnormal_homeostasis0.32004388
138MP0002752_abnormal_somatic_nervous0.31901289
139MP0009703_decreased_birth_body0.31730277
140MP0005253_abnormal_eye_physiology0.31576564
141MP0004811_abnormal_neuron_physiology0.31422146
142MP0003115_abnormal_respiratory_system0.30928616
143MP0005266_abnormal_metabolism0.30710377
144MP0004858_abnormal_nervous_system0.29947756
145MP0001849_ear_inflammation0.29132056
146MP0004270_analgesia0.28873452
147MP0003984_embryonic_growth_retardation0.27908426
148MP0003936_abnormal_reproductive_system0.27342833
149MP0002169_no_abnormal_phenotype0.26959865
150MP0002873_normal_phenotype0.26554143
151MP0003718_maternal_effect0.26523209
152MP0002092_abnormal_eye_morphology0.26160212
153MP0001545_abnormal_hematopoietic_system0.26123496
154MP0005397_hematopoietic_system_phenotyp0.26123496
155MP0009115_abnormal_fat_cell0.25974503
156MP0002088_abnormal_embryonic_growth/wei0.25456483
157MP0005645_abnormal_hypothalamus_physiol0.25108117
158MP0002735_abnormal_chemical_nociception0.24920957
159MP0001485_abnormal_pinna_reflex0.22564109
160MP0004019_abnormal_vitamin_homeostasis0.22136109
161MP0002132_abnormal_respiratory_system0.21853206
162MP0004197_abnormal_fetal_growth/weight/0.21843365

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.39908182
2Abnormal respiratory motile cilium morphology (HP:0005938)9.15187350
3Abnormal respiratory epithelium morphology (HP:0012253)9.15187350
4Rhinitis (HP:0012384)7.94417317
5Abnormal ciliary motility (HP:0012262)7.69074004
6Chronic bronchitis (HP:0004469)7.16543432
7Nasal polyposis (HP:0100582)5.88675656
8Infertility (HP:0000789)5.70797236
9Abnormality of the nasal mucosa (HP:0000433)4.74811540
10Bronchiectasis (HP:0002110)4.58615651
11Bronchitis (HP:0012387)4.55902293
12Nephronophthisis (HP:0000090)4.16579315
13Male infertility (HP:0003251)3.94443937
14Recurrent sinusitis (HP:0011108)3.58385824
15Tubulointerstitial nephritis (HP:0001970)3.25870741
16Recurrent otitis media (HP:0000403)3.25603717
17Abnormal spermatogenesis (HP:0008669)3.20262423
18Abnormality of the renal medulla (HP:0100957)3.10999879
19Medial flaring of the eyebrow (HP:0010747)3.09698626
20Abnormality of midbrain morphology (HP:0002418)2.95057208
21Molar tooth sign on MRI (HP:0002419)2.95057208
22Recurrent bronchitis (HP:0002837)2.82141534
23Hyperactive renin-angiotensin system (HP:0000841)2.79193590
24Atelectasis (HP:0100750)2.77508303
25Impulsivity (HP:0100710)2.76070958
26Tubular atrophy (HP:0000092)2.73709609
27Chronic otitis media (HP:0000389)2.69554438
28Supernumerary spleens (HP:0009799)2.40606202
29Tubulointerstitial abnormality (HP:0001969)2.34858826
30Azoospermia (HP:0000027)2.22868436
31Congenital primary aphakia (HP:0007707)2.18804730
32Gait imbalance (HP:0002141)2.16526808
33Anencephaly (HP:0002323)2.16074714
34Bile duct proliferation (HP:0001408)2.12353585
35Abnormal biliary tract physiology (HP:0012439)2.12353585
36Postaxial foot polydactyly (HP:0001830)2.11508316
37Pancreatic fibrosis (HP:0100732)2.11375082
38Hyperkalemia (HP:0002153)2.04081279
39Chronic sinusitis (HP:0011109)2.03554227
40Congenital hepatic fibrosis (HP:0002612)2.00687870
41Abnormality of the lower motor neuron (HP:0002366)2.00292321
42Facial cleft (HP:0002006)2.00105241
43Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1277722
44Dynein arm defect of respiratory motile cilia (HP:0012255)12.1654756
45Absent/shortened dynein arms (HP:0200106)12.1654756
46Male pseudohermaphroditism (HP:0000037)1.95491630
47Gonadotropin excess (HP:0000837)1.93579051
48Nephrogenic diabetes insipidus (HP:0009806)1.91639896
49Postaxial hand polydactyly (HP:0001162)1.86123840
50Decreased circulating renin level (HP:0003351)1.82888031
51Spastic tetraparesis (HP:0001285)1.82185256
52Oculomotor apraxia (HP:0000657)1.79037119
53Polydipsia (HP:0001959)1.78156239
54Abnormal drinking behavior (HP:0030082)1.78156239
55Stage 5 chronic kidney disease (HP:0003774)1.77407355
56Poor coordination (HP:0002370)1.76598016
57Absent frontal sinuses (HP:0002688)1.75102223
58Hypoplasia of the capital femoral epiphysis (HP:0003090)1.74141139
59True hermaphroditism (HP:0010459)1.73498894
60Abnormality of dentin (HP:0010299)1.73100978
61Renal salt wasting (HP:0000127)1.71881722
62Cystic liver disease (HP:0006706)1.71264209
63Short ribs (HP:0000773)1.68737934
64Absent rod-and cone-mediated responses on ERG (HP:0007688)1.65912513
65Furrowed tongue (HP:0000221)1.63341533
66Abnormality of the renal cortex (HP:0011035)1.61233976
67Cone-rod dystrophy (HP:0000548)1.60503621
68Fibular hypoplasia (HP:0003038)1.59954363
69Pancreatic cysts (HP:0001737)1.59776326
70Nephropathy (HP:0000112)1.59301272
71Aplasia/Hypoplasia of the spleen (HP:0010451)1.59127435
72Asplenia (HP:0001746)1.59042428
73Heterotopia (HP:0002282)1.57944584
74Aplasia/Hypoplasia of the lens (HP:0008063)1.57294775
75Tubulointerstitial fibrosis (HP:0005576)1.57016709
76Dyschromatopsia (HP:0007641)1.56808052
77Genital tract atresia (HP:0001827)1.51394419
78Vaginal atresia (HP:0000148)1.51362737
79Abnormality of renal excretion (HP:0011036)1.50892045
80Tongue fasciculations (HP:0001308)1.50708868
81Hyperaldosteronism (HP:0000859)1.50411434
82Abnormal rod and cone electroretinograms (HP:0008323)1.48754878
83Abnormality of the dental root (HP:0006486)1.48698571
84Taurodontia (HP:0000679)1.48698571
85Abnormality of permanent molar morphology (HP:0011071)1.48698571
86Broad distal phalanx of finger (HP:0009836)1.48380334
87Aplasia/Hypoplasia of the tongue (HP:0010295)1.48285391
88Decreased central vision (HP:0007663)1.47431784
89Median cleft lip (HP:0000161)1.47376707
90Cholecystitis (HP:0001082)1.43793396
91Abnormal gallbladder physiology (HP:0012438)1.43793396
92Abdominal situs inversus (HP:0003363)1.42995574
93Abnormality of abdominal situs (HP:0011620)1.42995574
94Abnormality of macular pigmentation (HP:0008002)1.41172388
95Preaxial hand polydactyly (HP:0001177)1.40931450
96Sloping forehead (HP:0000340)1.40663348
97Amyotrophic lateral sclerosis (HP:0007354)1.39555954
98Abnormality of chloride homeostasis (HP:0011422)1.39021069
99Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.38368648
100Absent epiphyses (HP:0010577)1.38368648
101Abnormality of molar (HP:0011077)1.35715326
102Abnormality of molar morphology (HP:0011070)1.35715326
103Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.35299197
104Abnormality of the dental pulp (HP:0006479)1.34415138
105Chronic hepatic failure (HP:0100626)1.34262787
106Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.34215995
107Abnormality of renin-angiotensin system (HP:0000847)1.34190458
108Muscle fibrillation (HP:0010546)1.33442144
109Occipital encephalocele (HP:0002085)1.31316302
110Abnormal urine output (HP:0012590)1.26823254
111Bony spicule pigmentary retinopathy (HP:0007737)1.25841802
112Hypokalemic alkalosis (HP:0001949)1.25034769
113Short humerus (HP:0005792)1.24857460
114Microglossia (HP:0000171)1.24762164
115Sclerocornea (HP:0000647)1.23681144
116Renal dysplasia (HP:0000110)1.22577896
117Degeneration of anterior horn cells (HP:0002398)1.22097853
118Abnormality of the anterior horn cell (HP:0006802)1.22097853
119Choroideremia (HP:0001139)1.21907473
120Hyponatremia (HP:0002902)1.21028186
121Short thorax (HP:0010306)1.19990779
122Bell-shaped thorax (HP:0001591)1.19740047
123Cleft eyelid (HP:0000625)1.19573717
124Impaired proprioception (HP:0010831)1.19196466
125Aplasia/hypoplasia of the humerus (HP:0006507)1.18768449
126Hand muscle atrophy (HP:0009130)1.12935342
127Bifid scrotum (HP:0000048)1.10249991
128Glucose intolerance (HP:0000833)1.09361902
129Retinitis pigmentosa (HP:0000510)1.07186906
130Abnormality of the frontal sinuses (HP:0002687)1.04833697
131Fetal akinesia sequence (HP:0001989)1.02383618
132Portal hypertension (HP:0001409)1.02304583
133Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.02171573
134Severe visual impairment (HP:0001141)1.00725059
135Narrow forehead (HP:0000341)0.96729271

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.93307826
2PDK47.93307826
3TESK15.89056377
4MST45.37594528
5PDK25.29809351
6PRKD34.39368870
7ICK3.76127771
8PNCK2.70608421
9PTK2B2.04515146
10NME11.98264078
11MAP3K21.89629684
12NEK21.79535447
13MAPK151.75034976
14STK381.65509841
15BCR1.60016894
16WNK41.53890964
17TESK21.49766248
18WEE11.44655810
19STK391.43821141
20MAP4K21.37929683
21DYRK1B1.36053346
22INSRR1.26467841
23MAP3K41.24004172
24FRK1.23983326
25MST1R1.13833216
26SMG11.13294015
27TTK1.11748092
28DYRK31.10500390
29CSK1.05227336
30ARAF1.02101325
31CDK120.99473624
32MAP3K30.95623270
33CCNB10.95009008
34PDK10.91209460
35AKT30.90419809
36BRAF0.89927965
37STK38L0.87660196
38CHEK20.86834643
39WNK30.84831517
40PLK40.83124987
41MAP3K70.82898014
42STK100.81181029
43ERBB30.80318895
44MUSK0.78822140
45EPHA30.78680384
46TYRO30.76951670
47CDC70.76272664
48EPHB10.76006225
49IRAK10.74668034
50BRD40.74171646
51TLK10.73272002
52PASK0.72418385
53PBK0.71186029
54MAP2K70.70796105
55TRPM70.66542808
56CHEK10.66355279
57PLK10.66058673
58BUB10.63799990
59PRKCI0.62447617
60ERBB20.62236730
61LATS10.60630415
62STK30.58257238
63MAP2K60.58119324
64PRKCQ0.57441812
65ACVR1B0.56382595
66PLK20.53279515
67WNK10.52858570
68NLK0.51754401
69MAPKAPK30.51373990
70BMPR1B0.50935396
71OXSR10.50927119
72LRRK20.50604209
73ATR0.49823980
74EPHA20.48668368
75ATM0.48410472
76PRKAA20.48355317
77FER0.48193025
78MAPK130.47836764
79SGK10.44975353
80ADRBK20.44705297
81PINK10.44202613
82PRKCG0.43659746
83NTRK20.43526442
84ROCK10.40689808
85PDPK10.40303184
86EIF2AK10.40260776
87PAK10.39676178
88LMTK20.39593355
89CAMKK10.38156386
90RIPK10.36350634
91GRK10.35515876
92AURKA0.33674279
93TRIM280.33188972
94TBK10.32460625
95PRKACA0.31538545
96MTOR0.30955947
97CAMK2G0.30207062
98SRPK10.29421580
99PIM20.28488322
100TSSK60.27219536
101PRKCE0.27161178
102MKNK20.26031070
103MAP4K10.25659760
104PRKG10.25217537
105PRKCA0.25175105
106PAK40.25102117
107PLK30.24709156
108CAMK2A0.23831474
109ROCK20.23117857
110CDK20.22743845
111DAPK10.22249071
112MAP2K40.21990284
113DYRK1A0.21933214
114MAP3K100.21924440
115CASK0.21526642
116CSNK2A10.21299932
117EEF2K0.20462731
118ADRBK10.20441915
119CSNK2A20.20110733
120STK160.19644461
121PRKCH0.19349061
122PRPF4B0.18616253
123YES10.18518407
124BRSK20.18348291
125PIM10.18264652
126ZAP700.18214936
127AURKB0.17769608
128PRKCZ0.17572554
129RPS6KA20.17523259
130DDR20.17467650
131SGK2230.17103380
132SGK4940.17103380
133RIPK40.16797035
134ABL10.16789544
135MAPKAPK50.16029463
136BRSK10.15863328
137VRK10.15845914
138CSNK1D0.15109746
139CAMK1G0.14863698
140MARK30.14709003
141CDK10.14074925
142DYRK20.13116189
143EIF2AK30.13099816
144STK240.12832408
145GSK3B0.12250241
146NEK60.12010045
147CSNK1E0.11961809
148RPS6KB10.11862346
149MINK10.09974956
150CDK70.09609685
151PRKDC0.09143151
152PRKAA10.09064204
153NEK10.08477292
154RPS6KA10.07720766
155CDK40.07006757
156PAK20.06424684
157IRAK20.06182337
158MARK20.05353983
159MAPK80.04789283
160CDK150.04767714
161CDK180.04740536
162NTRK30.03719744
163CDK30.02787994
164PRKCD0.02775234

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003604.54290799
2Histidine metabolism_Homo sapiens_hsa003404.23471068
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.03228910
4Vitamin B6 metabolism_Homo sapiens_hsa007503.76957975
5Fatty acid biosynthesis_Homo sapiens_hsa000613.63690246
6Tyrosine metabolism_Homo sapiens_hsa003503.54488633
7Basal transcription factors_Homo sapiens_hsa030223.31649428
8Pyruvate metabolism_Homo sapiens_hsa006203.31430458
9beta-Alanine metabolism_Homo sapiens_hsa004102.85747143
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.79452052
11Fanconi anemia pathway_Homo sapiens_hsa034602.64333259
12Retinol metabolism_Homo sapiens_hsa008302.45977358
13Linoleic acid metabolism_Homo sapiens_hsa005912.35582647
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.33179351
15Glucagon signaling pathway_Homo sapiens_hsa049222.32616133
16Propanoate metabolism_Homo sapiens_hsa006402.32352186
17RNA transport_Homo sapiens_hsa030132.28991167
18Caffeine metabolism_Homo sapiens_hsa002322.23955560
19Selenocompound metabolism_Homo sapiens_hsa004502.15546086
20Oocyte meiosis_Homo sapiens_hsa041142.05202873
21Pentose phosphate pathway_Homo sapiens_hsa000301.94324482
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.91418418
23Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.90595987
24Fructose and mannose metabolism_Homo sapiens_hsa000511.80757780
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.80266177
26Glycerolipid metabolism_Homo sapiens_hsa005611.79883676
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.72203713
28Purine metabolism_Homo sapiens_hsa002301.72031330
29Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.71925676
30mRNA surveillance pathway_Homo sapiens_hsa030151.68489422
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.61768010
32ABC transporters_Homo sapiens_hsa020101.59286332
33DNA replication_Homo sapiens_hsa030301.58508533
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.58430129
35Homologous recombination_Homo sapiens_hsa034401.57546293
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.57380416
37Huntingtons disease_Homo sapiens_hsa050161.56557176
38PPAR signaling pathway_Homo sapiens_hsa033201.49515924
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.49210410
40Sphingolipid metabolism_Homo sapiens_hsa006001.46979337
41Glycerophospholipid metabolism_Homo sapiens_hsa005641.45118953
42Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.42037539
43Tight junction_Homo sapiens_hsa045301.40589444
44Olfactory transduction_Homo sapiens_hsa047401.38119509
45Amphetamine addiction_Homo sapiens_hsa050311.36743446
46Proteasome_Homo sapiens_hsa030501.30483211
47Pyrimidine metabolism_Homo sapiens_hsa002401.28534027
48Biosynthesis of amino acids_Homo sapiens_hsa012301.26790537
49Carbon metabolism_Homo sapiens_hsa012001.26080680
50Mismatch repair_Homo sapiens_hsa034301.25328925
51Salivary secretion_Homo sapiens_hsa049701.18653924
52Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.14536464
53Peroxisome_Homo sapiens_hsa041461.13034374
54Spliceosome_Homo sapiens_hsa030401.11269322
55Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.09994755
56Butanoate metabolism_Homo sapiens_hsa006501.09645924
57Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.09540006
58Mineral absorption_Homo sapiens_hsa049781.07598150
59Nicotine addiction_Homo sapiens_hsa050331.06142932
60Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.04834128
61Antigen processing and presentation_Homo sapiens_hsa046121.03604708
62Cardiac muscle contraction_Homo sapiens_hsa042600.99064803
63Dorso-ventral axis formation_Homo sapiens_hsa043200.98627339
64Primary bile acid biosynthesis_Homo sapiens_hsa001200.97289675
65RNA degradation_Homo sapiens_hsa030180.96834315
66Base excision repair_Homo sapiens_hsa034100.96692090
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.96405707
68Collecting duct acid secretion_Homo sapiens_hsa049660.96396922
69Fat digestion and absorption_Homo sapiens_hsa049750.93550453
70Glutathione metabolism_Homo sapiens_hsa004800.91894332
71Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.91113212
72Fatty acid degradation_Homo sapiens_hsa000710.90307078
73Starch and sucrose metabolism_Homo sapiens_hsa005000.89676635
74Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.87490140
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.83674049
76Ether lipid metabolism_Homo sapiens_hsa005650.83403205
77Systemic lupus erythematosus_Homo sapiens_hsa053220.81550782
78Cell cycle_Homo sapiens_hsa041100.81444458
79Circadian rhythm_Homo sapiens_hsa047100.80098967
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.75104170
81Nucleotide excision repair_Homo sapiens_hsa034200.72286500
82Synaptic vesicle cycle_Homo sapiens_hsa047210.70869024
83Fatty acid metabolism_Homo sapiens_hsa012120.70738065
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.70501224
85Insulin secretion_Homo sapiens_hsa049110.69039286
86Long-term potentiation_Homo sapiens_hsa047200.67018872
87Taste transduction_Homo sapiens_hsa047420.64967936
88Drug metabolism - other enzymes_Homo sapiens_hsa009830.64469871
89Chemical carcinogenesis_Homo sapiens_hsa052040.64225078
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62695354
91Renin-angiotensin system_Homo sapiens_hsa046140.61773210
92Arachidonic acid metabolism_Homo sapiens_hsa005900.61105700
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.59932600
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.59487224
95Renin secretion_Homo sapiens_hsa049240.59290810
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.58761782
97Estrogen signaling pathway_Homo sapiens_hsa049150.57468591
98Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57215749
99Hedgehog signaling pathway_Homo sapiens_hsa043400.55506876
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51972063
101Choline metabolism in cancer_Homo sapiens_hsa052310.50099427
102Calcium signaling pathway_Homo sapiens_hsa040200.48756336
103Serotonergic synapse_Homo sapiens_hsa047260.47941789
104cAMP signaling pathway_Homo sapiens_hsa040240.47935071
105Epstein-Barr virus infection_Homo sapiens_hsa051690.46502720
106Tryptophan metabolism_Homo sapiens_hsa003800.45353729
107Arginine and proline metabolism_Homo sapiens_hsa003300.44670487
108Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44667424
109Adherens junction_Homo sapiens_hsa045200.44452663
110Alcoholism_Homo sapiens_hsa050340.44325084
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43922026
112Metabolic pathways_Homo sapiens_hsa011000.43139530
113Central carbon metabolism in cancer_Homo sapiens_hsa052300.40531331
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.39572856
115Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.38910169
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38602132
117Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38384916
118Inositol phosphate metabolism_Homo sapiens_hsa005620.38117294
119Legionellosis_Homo sapiens_hsa051340.37474231
120Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36979098
121Circadian entrainment_Homo sapiens_hsa047130.36963102
122Notch signaling pathway_Homo sapiens_hsa043300.36801729
123Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36737200
124Nitrogen metabolism_Homo sapiens_hsa009100.35928939
125Basal cell carcinoma_Homo sapiens_hsa052170.35368189
126Cocaine addiction_Homo sapiens_hsa050300.35208143
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35170259
128Viral carcinogenesis_Homo sapiens_hsa052030.35092008
129Pancreatic secretion_Homo sapiens_hsa049720.33774220
130Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33473780
131Protein digestion and absorption_Homo sapiens_hsa049740.33369542
132Leukocyte transendothelial migration_Homo sapiens_hsa046700.29176552
133Steroid biosynthesis_Homo sapiens_hsa001000.28357167
134Thyroid hormone synthesis_Homo sapiens_hsa049180.27430525
135Type I diabetes mellitus_Homo sapiens_hsa049400.27329248
136Hepatitis C_Homo sapiens_hsa051600.25335226
137AMPK signaling pathway_Homo sapiens_hsa041520.23518297
138Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.23194158
139Phototransduction_Homo sapiens_hsa047440.22926244
140Glutamatergic synapse_Homo sapiens_hsa047240.21431642
141Hippo signaling pathway_Homo sapiens_hsa043900.21164473
142VEGF signaling pathway_Homo sapiens_hsa043700.20974082
143Non-homologous end-joining_Homo sapiens_hsa034500.20832875
144Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.20740874
145Hematopoietic cell lineage_Homo sapiens_hsa046400.20219200
146Endocytosis_Homo sapiens_hsa041440.19786277
147RNA polymerase_Homo sapiens_hsa030200.19654369
148Regulation of autophagy_Homo sapiens_hsa041400.19477818
149Vascular smooth muscle contraction_Homo sapiens_hsa042700.17955447
150Bile secretion_Homo sapiens_hsa049760.16716723
151Graft-versus-host disease_Homo sapiens_hsa053320.15751483
152Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.14466964
153Vitamin digestion and absorption_Homo sapiens_hsa049770.13899364
154Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.13429323
155Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.12837723
156Complement and coagulation cascades_Homo sapiens_hsa046100.12465386
157Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.12039873
158Allograft rejection_Homo sapiens_hsa053300.12024525
159Ovarian steroidogenesis_Homo sapiens_hsa049130.10467344
160Gastric acid secretion_Homo sapiens_hsa049710.10259259
161Autoimmune thyroid disease_Homo sapiens_hsa053200.10063386
162Jak-STAT signaling pathway_Homo sapiens_hsa046300.09960898
163Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.09146828

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