VWA5B2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1Golgi transport vesicle coating (GO:0048200)5.26122663
2COPI coating of Golgi vesicle (GO:0048205)5.26122663
3endocrine pancreas development (GO:0031018)4.90065016
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.88164328
5positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.85100841
6cellular potassium ion homeostasis (GO:0030007)4.71062333
7insulin secretion (GO:0030073)4.47149969
8positive regulation of synapse maturation (GO:0090129)4.38940997
9regulation of short-term neuronal synaptic plasticity (GO:0048172)4.38857628
10regulation of synapse structural plasticity (GO:0051823)4.38605867
11peptide hormone processing (GO:0016486)4.30684697
12regulation of synaptic vesicle exocytosis (GO:2000300)4.24606092
13positive regulation of neurotransmitter transport (GO:0051590)4.21514219
14synaptic vesicle maturation (GO:0016188)4.04490235
15positive regulation of insulin secretion (GO:0032024)3.98105402
16positive regulation of neurotransmitter secretion (GO:0001956)3.97858509
17detection of calcium ion (GO:0005513)3.97780782
18ionotropic glutamate receptor signaling pathway (GO:0035235)3.96582472
19glandular epithelial cell differentiation (GO:0002067)3.95646519
20sodium ion export (GO:0071436)3.91172205
21exploration behavior (GO:0035640)3.91013061
22regulation of neurotransmitter levels (GO:0001505)3.85818277
23dendritic spine morphogenesis (GO:0060997)3.85562353
24regulation of ARF protein signal transduction (GO:0032012)3.83951284
25regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.81853396
26regulation of synaptic vesicle transport (GO:1902803)3.80809480
27synaptic vesicle exocytosis (GO:0016079)3.80392292
28regulation of insulin secretion (GO:0050796)3.76316316
29axon ensheathment in central nervous system (GO:0032291)3.68814284
30central nervous system myelination (GO:0022010)3.68814284
31cerebellar granule cell differentiation (GO:0021707)3.67434501
32neuronal action potential propagation (GO:0019227)3.65564130
33regulation of type B pancreatic cell apoptotic process (GO:2000674)3.65168752
34retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.61271626
35positive regulation of dendritic spine development (GO:0060999)3.59840152
36potassium ion homeostasis (GO:0055075)3.56260423
37L-amino acid import (GO:0043092)3.55438245
38synaptic vesicle docking involved in exocytosis (GO:0016081)3.52609000
39regulation of synaptic plasticity (GO:0048167)3.51577073
40regulation of neurotransmitter transport (GO:0051588)3.51453355
41proline transport (GO:0015824)3.51209576
42protein maturation by protein folding (GO:0022417)3.50500971
43regulation of excitatory postsynaptic membrane potential (GO:0060079)3.47819531
44negative regulation of dendrite morphogenesis (GO:0050774)3.45355083
45regulation of peptide hormone secretion (GO:0090276)3.45132144
46glutamate secretion (GO:0014047)3.44864147
47potassium ion import (GO:0010107)3.43187368
48regulation of synapse maturation (GO:0090128)3.43109156
49type B pancreatic cell development (GO:0003323)3.42184409
50glycine transport (GO:0015816)3.42095530
51synaptic vesicle endocytosis (GO:0048488)3.41837941
52regulation of peptide secretion (GO:0002791)3.40922917
53regulation of calcium ion-dependent exocytosis (GO:0017158)3.39106096
54positive regulation of synaptic transmission, GABAergic (GO:0032230)3.39100526
55peptide hormone secretion (GO:0030072)3.38385943
56negative regulation of synaptic transmission, GABAergic (GO:0032229)3.34455849
57regulation of postsynaptic membrane potential (GO:0060078)3.32603461
58neuron-neuron synaptic transmission (GO:0007270)3.32534152
59neuron cell-cell adhesion (GO:0007158)3.31896674
60glandular epithelial cell development (GO:0002068)3.31337178
61positive regulation of peptide hormone secretion (GO:0090277)3.30207918
62regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.30102584
63COPII vesicle coating (GO:0048208)3.26625213
64peptide secretion (GO:0002790)3.26194659
65positive regulation of peptide secretion (GO:0002793)3.25630224
66neurotransmitter secretion (GO:0007269)3.25459329
67neuromuscular synaptic transmission (GO:0007274)3.24450396
68maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.22677465
69glutamate receptor signaling pathway (GO:0007215)3.21483845
70response to pheromone (GO:0019236)3.19407574
71regulation of vesicle fusion (GO:0031338)3.19241728
72nitric oxide mediated signal transduction (GO:0007263)3.19047555
73cellular response to glucagon stimulus (GO:0071377)3.17402640
74neurotransmitter-gated ion channel clustering (GO:0072578)3.16866132
75regulation of voltage-gated calcium channel activity (GO:1901385)3.16673958
76locomotory exploration behavior (GO:0035641)3.15573485
77positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.15545015
78positive regulation of vesicle fusion (GO:0031340)3.13113702
79auditory behavior (GO:0031223)3.09138217
80positive regulation of exocytosis (GO:0045921)3.07897217
81chemosensory behavior (GO:0007635)3.06800692
82response to dietary excess (GO:0002021)3.06360501
83neuromuscular process controlling balance (GO:0050885)3.06324881
84dendritic spine organization (GO:0097061)3.06081236
85amino acid import (GO:0043090)3.04975559
86regulation of hormone secretion (GO:0046883)3.04757226
87response to gravity (GO:0009629)3.04421593
88negative regulation of catecholamine secretion (GO:0033604)3.02771460
89neuromuscular process controlling posture (GO:0050884)3.00875100
90long-term memory (GO:0007616)2.98616389
91regulation of dendritic spine development (GO:0060998)2.97781106
92membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.97326981
93membrane depolarization (GO:0051899)2.97019185
94innervation (GO:0060384)2.96639379
95regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.96521619
96regulation of exocytosis (GO:0017157)2.95111189
97calcium ion-dependent exocytosis (GO:0017156)2.94312695
98synaptic transmission (GO:0007268)2.93722947
99signal release (GO:0023061)2.93358759
100intraspecies interaction between organisms (GO:0051703)2.89242623
101social behavior (GO:0035176)2.89242623
102phosphorelay signal transduction system (GO:0000160)2.89167624
103regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.88004331
104protein retention in ER lumen (GO:0006621)2.87864992
105regulation of neuronal synaptic plasticity (GO:0048168)2.87835467
106cellular potassium ion transport (GO:0071804)2.87471197
107potassium ion transmembrane transport (GO:0071805)2.87471197
108exocrine pancreas development (GO:0031017)2.87405450
109vocalization behavior (GO:0071625)2.87025037
110activation of protein kinase A activity (GO:0034199)2.86318097
111cerebellar Purkinje cell layer development (GO:0021680)2.86229218
112gamma-aminobutyric acid transport (GO:0015812)2.85873929
113regulation of dendritic spine morphogenesis (GO:0061001)2.85625578
114vesicle docking involved in exocytosis (GO:0006904)2.85434180
115regulation of synaptic transmission (GO:0050804)2.83989327
116long-term synaptic potentiation (GO:0060291)2.83338625
117regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.81984096
118membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80683566
119negative regulation of norepinephrine secretion (GO:0010700)2.78849539
120regulation of glutamate receptor signaling pathway (GO:1900449)2.78516032
121vesicle coating (GO:0006901)2.77644022
122neurotransmitter transport (GO:0006836)2.76699737
123regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178)2.76501727
124regulation of peptide transport (GO:0090087)2.75159531
125hormone secretion (GO:0046879)2.74248335
126cellular sodium ion homeostasis (GO:0006883)2.72650829
127positive regulation of dendrite development (GO:1900006)2.72459210
128synaptic vesicle transport (GO:0048489)2.71753762
129establishment of synaptic vesicle localization (GO:0097480)2.71753762
130regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68639246
131negative regulation of insulin secretion (GO:0046676)2.68553528
132presynaptic membrane assembly (GO:0097105)2.68527152
133cerebellar Purkinje cell differentiation (GO:0021702)2.67422630
134positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.66745689
135membrane repolarization during action potential (GO:0086011)2.65191372
136ER overload response (GO:0006983)2.64056610
137calcium ion import (GO:0070509)2.64009483
138regulation of beta-amyloid formation (GO:1902003)2.63265807
139neuronal ion channel clustering (GO:0045161)2.62908505
140positive regulation of hormone secretion (GO:0046887)2.61729782
141peptide transport (GO:0015833)2.61035534
142protein localization to synapse (GO:0035418)2.59897505
143positive regulation of membrane potential (GO:0045838)2.59253814
144synaptic transmission, glutamatergic (GO:0035249)2.58110908
145postsynaptic membrane organization (GO:0001941)2.57733604
146neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.57305429
147regulation of norepinephrine secretion (GO:0014061)2.56174328
148regulation of glucocorticoid secretion (GO:2000849)2.55937470
149cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.55336988
150regulation of neurotransmitter secretion (GO:0046928)2.54892204
151regulation of long-term neuronal synaptic plasticity (GO:0048169)2.54296425
152hormone transport (GO:0009914)2.53357925
153suckling behavior (GO:0001967)2.53216863
154regulation of oxidative phosphorylation (GO:0002082)2.53031332
155membrane depolarization during action potential (GO:0086010)2.51907118
156inner ear receptor cell development (GO:0060119)2.51789234
157astrocyte differentiation (GO:0048708)2.50818302
158toxin metabolic process (GO:0009404)2.49022930

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.08471192
2GBX2_23144817_ChIP-Seq_PC3_Human3.35605425
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.20598954
4REST_21632747_ChIP-Seq_MESCs_Mouse2.76557529
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.70081479
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.42847679
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.40159812
8* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.36794319
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.35819971
10* EZH2_27304074_Chip-Seq_ESCs_Mouse2.35700220
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.34190652
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.32634347
13* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.29021071
14REST_18959480_ChIP-ChIP_MESCs_Mouse2.18931748
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.16821001
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.13917805
17DROSHA_22980978_ChIP-Seq_HELA_Human2.12942549
18* EZH2_27294783_Chip-Seq_ESCs_Mouse2.11741759
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.08942102
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.07302499
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.05937281
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.02947799
23RNF2_18974828_ChIP-Seq_MESCs_Mouse2.02442398
24EZH2_18974828_ChIP-Seq_MESCs_Mouse2.02442398
25ERG_21242973_ChIP-ChIP_JURKAT_Human2.01519353
26EED_16625203_ChIP-ChIP_MESCs_Mouse2.00425346
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.91057944
28IGF1R_20145208_ChIP-Seq_DFB_Human1.90642312
29* RNF2_27304074_Chip-Seq_ESCs_Mouse1.87669608
30CTCF_27219007_Chip-Seq_Bcells_Human1.84490994
31RARB_27405468_Chip-Seq_BRAIN_Mouse1.82589508
32* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79876097
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.77025948
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.74729403
35* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69982853
36LXR_22292898_ChIP-Seq_THP-1_Human1.64220039
37KDM2B_26808549_Chip-Seq_K562_Human1.62545507
38NR3C1_23031785_ChIP-Seq_PC12_Mouse1.60400482
39SMAD4_21799915_ChIP-Seq_A2780_Human1.57693487
40ZFP57_27257070_Chip-Seq_ESCs_Mouse1.55639122
41EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.55001606
42ZNF274_21170338_ChIP-Seq_K562_Hela1.53975320
43SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.51288024
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47908558
45PIAS1_25552417_ChIP-Seq_VCAP_Human1.44738042
46P68_20966046_ChIP-Seq_HELA_Human1.42782422
47TET1_21490601_ChIP-Seq_MESCs_Mouse1.42669602
48STAT3_23295773_ChIP-Seq_U87_Human1.39126187
49ZFP281_18757296_ChIP-ChIP_E14_Mouse1.37397594
50P300_19829295_ChIP-Seq_ESCs_Human1.33980411
51ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.33872041
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32894015
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32621259
54RNF2_27304074_Chip-Seq_NSC_Mouse1.32293145
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31843469
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.31354005
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30273464
58ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.28860620
59SMC4_20622854_ChIP-Seq_HELA_Human1.28587023
60OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.26944423
61VDR_22108803_ChIP-Seq_LS180_Human1.25709783
62TAF15_26573619_Chip-Seq_HEK293_Human1.24761254
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.24061394
64RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.22775900
65MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.22411719
66SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.21322953
67* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20015431
68DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.19573717
69CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.16774514
70ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15783787
71SMAD3_21741376_ChIP-Seq_EPCs_Human1.14217967
72TCF4_23295773_ChIP-Seq_U87_Human1.14160694
73PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.13197774
74PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13185954
75TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11724712
76YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11302095
77AR_19668381_ChIP-Seq_PC3_Human1.11285973
78OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11176866
79SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10747477
80CREB1_26743006_Chip-Seq_LNCaP_Human1.09611335
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.09587281
82RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.08939548
83ZFP281_27345836_Chip-Seq_ESCs_Mouse1.08848665
84RING1B_27294783_Chip-Seq_NPCs_Mouse1.07872840
85OCT4_19829295_ChIP-Seq_ESCs_Human1.07809834
86RUNX2_22187159_ChIP-Seq_PCA_Human1.04979545
87TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.04794722
88LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04221903
89AR_25329375_ChIP-Seq_VCAP_Human1.03987027
90WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03069781
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03040430
92NANOG_18555785_Chip-Seq_ESCs_Mouse1.02764447
93SMAD3_21741376_ChIP-Seq_ESCs_Human1.02690824
94CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.01500477
95SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00674298
96* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.99939296
97CDX2_19796622_ChIP-Seq_MESCs_Mouse0.99931903
98SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98877856
99WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97572996
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97335042
101PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96817633
102MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.96586260
103* RING1B_27294783_Chip-Seq_ESCs_Mouse0.96546533
104NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96054378
105STAT6_21828071_ChIP-Seq_BEAS2B_Human0.94373586
106TET1_21451524_ChIP-Seq_MESCs_Mouse0.94296662
107GATA1_22025678_ChIP-Seq_K562_Human0.94199728
108RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93900005
109SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.93518085
110TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93112549
111SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.93069260
112KLF4_19829295_ChIP-Seq_ESCs_Human0.92303018
113NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.92203491
114ESR2_21235772_ChIP-Seq_MCF-7_Human0.91740660
115EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91690580
116GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.91213584
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90193938
118P53_22387025_ChIP-Seq_ESCs_Mouse0.90057038
119MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89322888
120DPY_21335234_ChIP-Seq_ESCs_Mouse0.88343753
121DNAJC2_21179169_ChIP-ChIP_NT2_Human0.88221724
122SMAD4_21741376_ChIP-Seq_ESCs_Human0.87630738
123REST_19997604_ChIP-ChIP_NEURONS_Mouse0.86591590
124P53_22127205_ChIP-Seq_FIBROBLAST_Human0.86506567
125BCAT_22108803_ChIP-Seq_LS180_Human0.86440001
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.85454490
127ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.85341599
128ARNT_22903824_ChIP-Seq_MCF-7_Human0.84211855
129SMAD4_21741376_ChIP-Seq_HESCs_Human0.84161854
130FLI1_21867929_ChIP-Seq_TH2_Mouse0.83728689
131AR_21572438_ChIP-Seq_LNCaP_Human0.83725350
132CTCF_27219007_Chip-Seq_ERYTHROID_Human0.83712018
133BCOR_27268052_Chip-Seq_Bcells_Human0.83674032
134OCT4_20526341_ChIP-Seq_ESCs_Human0.83420808
135BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.83100666
136CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.82695987
137E2F1_20622854_ChIP-Seq_HELA_Human0.82605521
138ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.82235380
139GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82224942
140SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.80676073
141TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.80115664
142RACK7_27058665_Chip-Seq_MCF-7_Human0.78940471
143PHF8_20622854_ChIP-Seq_HELA_Human0.78426883
144TP53_20018659_ChIP-ChIP_R1E_Mouse0.78132538
145CTCF_20526341_ChIP-Seq_ESCs_Human0.77783526
146JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.77362652
147HTT_18923047_ChIP-ChIP_STHdh_Human0.77304857
148FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76567428
149SA1_27219007_Chip-Seq_Bcells_Human0.75114914
150UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.73378727

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003283_abnormal_digestive_organ3.71617383
2MP0002909_abnormal_adrenal_gland3.25840394
3MP0004859_abnormal_synaptic_plasticity3.22503679
4MP0004270_analgesia3.05961207
5MP0009780_abnormal_chondrocyte_physiolo3.04871791
6MP0005645_abnormal_hypothalamus_physiol2.99042806
7MP0000013_abnormal_adipose_tissue2.89093295
8MP0010386_abnormal_urinary_bladder2.79597609
9MP0004043_abnormal_pH_regulation2.76388672
10MP0002693_abnormal_pancreas_physiology2.76318162
11MP0005379_endocrine/exocrine_gland_phen2.64301713
12MP0003183_abnormal_peptide_metabolism2.55043787
13MP0002877_abnormal_melanocyte_morpholog2.53514373
14MP0001944_abnormal_pancreas_morphology2.51528017
15MP0003635_abnormal_synaptic_transmissio2.51068016
16MP0003880_abnormal_central_pattern2.49410484
17MP0003122_maternal_imprinting2.42086548
18MP0000678_abnormal_parathyroid_gland2.36776483
19MP0005646_abnormal_pituitary_gland2.34206518
20MP0003195_calcinosis2.26722859
21MP0003787_abnormal_imprinting2.22713941
22MP0002734_abnormal_mechanical_nocicepti2.20269446
23MP0006072_abnormal_retinal_apoptosis2.08055287
24MP0009745_abnormal_behavioral_response1.95366706
25MP0005423_abnormal_somatic_nervous1.92799059
26MP0002272_abnormal_nervous_system1.89676443
27MP0001986_abnormal_taste_sensitivity1.88437777
28MP0002063_abnormal_learning/memory/cond1.85159132
29MP0002638_abnormal_pupillary_reflex1.83714955
30MP0002733_abnormal_thermal_nociception1.82532377
31MP0002572_abnormal_emotion/affect_behav1.82080263
32MP0002064_seizures1.82036979
33MP0003123_paternal_imprinting1.80901358
34MP0002735_abnormal_chemical_nociception1.73156317
35MP0003329_amyloid_beta_deposits1.73140129
36MP0006276_abnormal_autonomic_nervous1.69171615
37MP0009046_muscle_twitch1.67448557
38MP0001970_abnormal_pain_threshold1.60903980
39MP0001188_hyperpigmentation1.59350701
40MP0002822_catalepsy1.56835371
41MP0001968_abnormal_touch/_nociception1.55583991
42MP0001502_abnormal_circadian_rhythm1.53658588
43MP0002837_dystrophic_cardiac_calcinosis1.52752033
44MP0001501_abnormal_sleep_pattern1.52751898
45MP0001486_abnormal_startle_reflex1.51290880
46MP0002078_abnormal_glucose_homeostasis1.48542541
47MP0006292_abnormal_olfactory_placode1.48348448
48MP0002557_abnormal_social/conspecific_i1.47884689
49MP0008004_abnormal_stomach_pH1.47439827
50MP0005220_abnormal_exocrine_pancreas1.45461995
51MP0002184_abnormal_innervation1.44226432
52MP0003879_abnormal_hair_cell1.39951513
53MP0000003_abnormal_adipose_tissue1.35529416
54MP0003690_abnormal_glial_cell1.35433623
55MP0005174_abnormal_tail_pigmentation1.35350085
56MP0000955_abnormal_spinal_cord1.34454092
57MP0002067_abnormal_sensory_capabilities1.31046455
58MP0000631_abnormal_neuroendocrine_gland1.30179323
59MP0001984_abnormal_olfaction1.26278230
60MP0002876_abnormal_thyroid_physiology1.25661820
61MP0005409_darkened_coat_color1.18633053
62MP0003172_abnormal_lysosome_physiology1.18481102
63MP0003631_nervous_system_phenotype1.18092772
64MP0002163_abnormal_gland_morphology1.17475260
65MP0008569_lethality_at_weaning1.15527749
66MP0000462_abnormal_digestive_system1.15217233
67MP0004811_abnormal_neuron_physiology1.14561205
68MP0001765_abnormal_ion_homeostasis1.13011056
69MP0000920_abnormal_myelination1.09546179
70MP0008961_abnormal_basal_metabolism1.07807695
71MP0001440_abnormal_grooming_behavior1.07313515
72MP0005535_abnormal_body_temperature1.05564582
73MP0003953_abnormal_hormone_level1.05199762
74MP0003633_abnormal_nervous_system1.01743477
75MP0004858_abnormal_nervous_system1.01590235
76MP0002751_abnormal_autonomic_nervous1.01261406
77MP0005386_behavior/neurological_phenoty0.99929672
78MP0004924_abnormal_behavior0.99929672
79MP0002882_abnormal_neuron_morphology0.99888100
80MP0002234_abnormal_pharynx_morphology0.99766735
81MP0002736_abnormal_nociception_after0.98987767
82MP0004264_abnormal_extraembryonic_tissu0.95954582
83MP0004145_abnormal_muscle_electrophysio0.95783846
84MP0001756_abnormal_urination0.95740939
85MP0005253_abnormal_eye_physiology0.95261176
86MP0000778_abnormal_nervous_system0.93786183
87MP0002069_abnormal_eating/drinking_beha0.92356806
88MP0008877_abnormal_DNA_methylation0.92253011
89MP0003136_yellow_coat_color0.92241474
90MP0003634_abnormal_glial_cell0.92220333
91MP0002066_abnormal_motor_capabilities/c0.92002802
92MP0003632_abnormal_nervous_system0.91979777
93MP0002229_neurodegeneration0.90798847
94MP0002928_abnormal_bile_duct0.89682260
95MP0003121_genomic_imprinting0.88405263
96MP0001664_abnormal_digestion0.87901309
97MP0005448_abnormal_energy_balance0.86661611
98MP0001963_abnormal_hearing_physiology0.86574901
99MP0001485_abnormal_pinna_reflex0.86292352
100MP0000639_abnormal_adrenal_gland0.84106513
101MP0002152_abnormal_brain_morphology0.82449214
102MP0002896_abnormal_bone_mineralization0.82185223
103MP0001299_abnormal_eye_distance/0.81888761
104MP0005171_absent_coat_pigmentation0.81278446
105MP0000613_abnormal_salivary_gland0.80880063
106MP0005499_abnormal_olfactory_system0.79639264
107MP0005394_taste/olfaction_phenotype0.79639264
108MP0001529_abnormal_vocalization0.79586185
109MP0005310_abnormal_salivary_gland0.78757338
110MP0004885_abnormal_endolymph0.77983098
111MP0004142_abnormal_muscle_tone0.75875463
112MP0005551_abnormal_eye_electrophysiolog0.75742647
113MP0001905_abnormal_dopamine_level0.75239969
114MP0000566_synostosis0.74151571
115MP0003045_fibrosis0.74119042
116MP0003119_abnormal_digestive_system0.72955361
117MP0005257_abnormal_intraocular_pressure0.72880308
118MP0000538_abnormal_urinary_bladder0.70748362
119MP0003959_abnormal_lean_body0.69622383
120MP0003137_abnormal_impulse_conducting0.69562692
121MP0004510_myositis0.69410748
122MP0008874_decreased_physiological_sensi0.67708422
123MP0010329_abnormal_lipoprotein_level0.66042224
124MP0003075_altered_response_to0.65792341
125MP0004742_abnormal_vestibular_system0.64614004
126MP0004019_abnormal_vitamin_homeostasis0.63718004
127MP0001177_atelectasis0.62820129
128MP0008872_abnormal_physiological_respon0.62520693
129MP0005332_abnormal_amino_acid0.61280319
130MP0000604_amyloidosis0.60548324

Predicted human phenotypes

RankGene SetZ-score
1Elevated circulating parathyroid hormone (PTH) level (HP:0003165)6.85425344
2Hyperinsulinemic hypoglycemia (HP:0000825)6.31532869
3Hypoglycemic seizures (HP:0002173)5.73418146
4Symptomatic seizures (HP:0011145)5.58737776
5Abnormality of calcium-phosphate metabolism (HP:0100530)5.15731743
6Hypoglycemic coma (HP:0001325)4.18646883
7Action tremor (HP:0002345)4.14596012
8Annular pancreas (HP:0001734)3.99079817
9Akinesia (HP:0002304)3.92440579
10Insulin-resistant diabetes mellitus (HP:0000831)3.86187545
11Visual hallucinations (HP:0002367)3.84394693
12Hyperglycemia (HP:0003074)3.82001785
13Pancreatic islet-cell hyperplasia (HP:0004510)3.74682947
14Abnormality of endocrine pancreas physiology (HP:0012093)3.73464424
15Abnormality of the pancreatic islet cells (HP:0006476)3.73464424
16Large for gestational age (HP:0001520)3.70833247
17Diplopia (HP:0000651)3.62620387
18Abnormality of binocular vision (HP:0011514)3.62620387
19Focal motor seizures (HP:0011153)3.60333265
20Agitation (HP:0000713)3.59939309
21Decreased circulating renin level (HP:0003351)3.59527893
22Hyperparathyroidism (HP:0000843)3.47091088
23Ketoacidosis (HP:0001993)3.37090442
24Late onset (HP:0003584)3.23519430
25Fetal akinesia sequence (HP:0001989)3.21138356
26Osteomalacia (HP:0002749)3.16717602
27Abnormal eating behavior (HP:0100738)3.14703761
28Spastic gait (HP:0002064)3.13415055
29EEG with generalized epileptiform discharges (HP:0011198)3.10571566
30Epileptiform EEG discharges (HP:0011182)3.06649539
31Hypsarrhythmia (HP:0002521)3.02804461
32Congenital malformation of the right heart (HP:0011723)3.02561256
33Double outlet right ventricle (HP:0001719)3.02561256
34Intention tremor (HP:0002080)2.96694012
35Abnormal pancreas size (HP:0012094)2.94993178
36Urinary bladder sphincter dysfunction (HP:0002839)2.88701784
37Hypokalemia (HP:0002900)2.87191989
38Torticollis (HP:0000473)2.85181449
39Epileptic encephalopathy (HP:0200134)2.84590301
40Pheochromocytoma (HP:0002666)2.77596945
41Supranuclear gaze palsy (HP:0000605)2.75910656
42Enlarged penis (HP:0000040)2.72365102
43Retinal atrophy (HP:0001105)2.71631211
44Atonic seizures (HP:0010819)2.71503037
45Obstructive sleep apnea (HP:0002870)2.70907110
46Amblyopia (HP:0000646)2.70714382
47Focal dystonia (HP:0004373)2.68910231
48Postural instability (HP:0002172)2.68127447
49Febrile seizures (HP:0002373)2.67184523
50Hyperthyroidism (HP:0000836)2.65109543
51Hypothermia (HP:0002045)2.63051254
52Poor eye contact (HP:0000817)2.62789812
53Cerebral hypomyelination (HP:0006808)2.62591044
54Diminished movement (HP:0002374)2.60950095
55Neurofibrillary tangles (HP:0002185)2.60114361
56Menstrual irregularities (HP:0000858)2.58576426
57Tetraplegia (HP:0002445)2.54917066
58Focal seizures (HP:0007359)2.54254083
59Impaired vibration sensation in the lower limbs (HP:0002166)2.53757055
60Clonus (HP:0002169)2.53225917
61Testicular atrophy (HP:0000029)2.51747460
62Status epilepticus (HP:0002133)2.51048313
63Neuroendocrine neoplasm (HP:0100634)2.48423883
64Abnormality of renin-angiotensin system (HP:0000847)2.44671045
65Dysmetria (HP:0001310)2.44458949
66Hyperphosphatemia (HP:0002905)2.44213188
67Ventricular fibrillation (HP:0001663)2.43081205
68Myokymia (HP:0002411)2.40934622
69Progressive cerebellar ataxia (HP:0002073)2.40428414
70Papilledema (HP:0001085)2.39032991
71Ankle clonus (HP:0011448)2.38867681
72Abnormality of potassium homeostasis (HP:0011042)2.37904534
73Craniofacial dystonia (HP:0012179)2.36402646
74Turricephaly (HP:0000262)2.32536519
75Bradykinesia (HP:0002067)2.31415330
76Delusions (HP:0000746)2.30159347
77Prominent metopic ridge (HP:0005487)2.30155544
78Generalized tonic-clonic seizures (HP:0002069)2.29076115
79Cortical visual impairment (HP:0100704)2.28904747
80Hypercortisolism (HP:0001578)2.28088709
81Anxiety (HP:0000739)2.24923932
82Depression (HP:0000716)2.24774262
83Neuronal loss in central nervous system (HP:0002529)2.23547943
84Gaze-evoked nystagmus (HP:0000640)2.23309988
85Unilateral renal agenesis (HP:0000122)2.23047362
86Urinary glycosaminoglycan excretion (HP:0003541)2.22029821
87Mucopolysacchariduria (HP:0008155)2.22029821
88Hemiparesis (HP:0001269)2.16608014
89Dysostosis multiplex (HP:0000943)2.15631792
90Abnormality of the fovea (HP:0000493)2.15400266
91Sleep apnea (HP:0010535)2.14539239
92Hyperkalemia (HP:0002153)2.13162969
93Abnormality of polysaccharide metabolism (HP:0011012)2.12535063
94Abnormality of glycosaminoglycan metabolism (HP:0004371)2.12535063
95Abnormality of mucopolysaccharide metabolism (HP:0011020)2.12535063
96Absence seizures (HP:0002121)2.12388225
97Polyphagia (HP:0002591)2.12323879
98Dysautonomia (HP:0002459)2.12073026
99Rigidity (HP:0002063)2.11808535
100Congenital glaucoma (HP:0001087)2.11326005
101Genetic anticipation (HP:0003743)2.10481987
102Hemiplegia (HP:0002301)2.09970543
103Failure to thrive in infancy (HP:0001531)2.09664430
104Adrenal overactivity (HP:0002717)2.07511554
105Choreoathetosis (HP:0001266)2.07261188
106Truncus arteriosus (HP:0001660)2.06765442
107Aplasia/Hypoplasia of the fovea (HP:0008060)2.06019555
108Hypoplasia of the fovea (HP:0007750)2.06019555
109Cerebral inclusion bodies (HP:0100314)2.02940320
110Impaired social interactions (HP:0000735)2.02723597
111Abnormal social behavior (HP:0012433)2.02723597
112Type II lissencephaly (HP:0007260)2.01908883
113Impaired vibratory sensation (HP:0002495)2.01677096
114Abnormality of the metopic suture (HP:0005556)2.01486616
115Congenital sensorineural hearing impairment (HP:0008527)1.99057361
116Blue irides (HP:0000635)1.98111412
117Mutism (HP:0002300)1.96899101
118Neonatal onset (HP:0003623)1.95277496
119Retinal dysplasia (HP:0007973)1.94201855
120Abnormality of ocular smooth pursuit (HP:0000617)1.93937240
121Dysdiadochokinesis (HP:0002075)1.93474682
122Restlessness (HP:0000711)1.91105395
123Limb dystonia (HP:0002451)1.90005234
124Absent speech (HP:0001344)1.89975869
125Increased circulating renin level (HP:0000848)1.89493868
126Intestinal atresia (HP:0011100)1.89223209
127Dialeptic seizures (HP:0011146)1.88801121
128Lower limb muscle weakness (HP:0007340)1.88582586
129Postural tremor (HP:0002174)1.87351771
130Testicular neoplasm (HP:0010788)1.87125971
131Hyperaldosteronism (HP:0000859)1.86934400
132Polydipsia (HP:0001959)1.86122811
133Abnormal drinking behavior (HP:0030082)1.86122811
134Insulin resistance (HP:0000855)1.85556426
135Truncal ataxia (HP:0002078)1.85002546
136Syncope (HP:0001279)1.82840204
137Urinary urgency (HP:0000012)1.82147591
138Prolonged QT interval (HP:0001657)1.80527571
139Hyperactive renin-angiotensin system (HP:0000841)1.79620140
140Growth hormone excess (HP:0000845)1.78965964
141Hypotension (HP:0002615)1.77384587
142Aplasia/hypoplasia of the uterus (HP:0008684)1.77267427
143Impaired smooth pursuit (HP:0007772)1.76768452
144Abnormality of magnesium homeostasis (HP:0004921)1.76622161
145Hypocalcemia (HP:0002901)1.73051478
146Labial hypoplasia (HP:0000066)1.71431249
147Hypophosphatemia (HP:0002148)1.71132605
148Drooling (HP:0002307)1.70941358
149Excessive salivation (HP:0003781)1.70941358
150Abnormal EKG (HP:0003115)1.69959815
151Gait imbalance (HP:0002141)1.69612302
152Psychosis (HP:0000709)1.69457810
153Conjugated hyperbilirubinemia (HP:0002908)1.66794428
154Generalized aminoaciduria (HP:0002909)1.66625715
155Macroorchidism (HP:0000053)1.64187255
156Atelectasis (HP:0100750)1.63629688
157Absent eyebrow (HP:0002223)1.63331340
158Muscular hypotonia of the trunk (HP:0008936)1.63166210

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR5.21381244
2MAPK154.94279330
3NTRK33.85991318
4PASK3.23243529
5WNK33.19963765
6PRKD32.43361400
7TAOK32.37428642
8HIPK22.23956889
9MAP3K22.19283904
10UHMK12.12623198
11NTRK12.03345361
12CASK1.96966228
13MAP2K71.92584565
14WNK41.91877640
15MARK11.79122984
16MAP3K91.70070659
17DAPK21.69989765
18PIK3CG1.56875264
19MAPK131.56384006
20CAMKK21.56153548
21MAP3K41.55211170
22TNIK1.52552446
23EPHA41.50706500
24MAP3K11.48425643
25NTRK21.46180619
26FRK1.44058971
27MAP2K61.28628683
28MINK11.26778156
29FGFR21.26754903
30SIK21.24452408
31CDC42BPA1.17865626
32GRK51.17667333
33TNK21.15480935
34PAK61.13528073
35PRKCH1.12416393
36WNK11.08997369
37CAMKK11.08173226
38PDPK11.04913160
39CDK51.04634117
40EEF2K1.03782487
41EPHA30.99282379
42MAP3K120.96779505
43BRD40.96737703
44DAPK10.95074421
45SGK2230.93956333
46SGK4940.93956333
47RIPK10.91294115
48PDK10.90056171
49LATS20.89496662
50PRKCE0.88460959
51PAK30.88319341
52AKT30.87543789
53PRKCG0.87275312
54KSR20.87003123
55PNCK0.86833165
56CDK150.85403904
57MAPK120.84067147
58SGK20.82173993
59MAP2K40.81526009
60CDK180.80514212
61MARK20.80062220
62PRKD20.79298614
63BMPR20.77841340
64CAMK2D0.77032988
65CAMK2B0.74509183
66CDK11A0.74397393
67DAPK30.74368365
68NEK60.74218846
69OXSR10.73149642
70DYRK1A0.72612789
71CDK140.72495467
72BRAF0.69949618
73RIPK40.69356918
74FER0.68336044
75BMPR1B0.66763088
76TYRO30.65747832
77SCYL20.65510745
78CAMK1D0.63746742
79RET0.63251381
80CAMK2A0.63239426
81CAMK2G0.62922589
82IRAK10.62790535
83PTK20.59577006
84ARAF0.58087035
85PINK10.58068008
86LMTK20.56869741
87RPS6KA20.56638518
88GRK70.56613874
89PRKCZ0.55433798
90SGK10.54758625
91ADRBK20.54746275
92MAPKAPK50.54211342
93CAMK10.52585304
94PRPF4B0.52266793
95MUSK0.52236321
96PRKG20.50129808
97CSNK1G20.49099069
98SIK10.49003642
99PRKAA10.47334672
100FGFR30.46646267
101SGK30.46454457
102MAP3K110.45590956
103CAMK40.45489650
104IRAK20.44271791
105CAMK1G0.44061786
106PDGFRA0.43656758
107STK380.42540273
108BRSK10.42185302
109BCR0.41556473
110MAPKAPK30.40191157
111TESK10.39891643
112CSNK1A10.39868786
113ALK0.39616927
114PLK20.38924531
115PRKACA0.38100974
116MAPK80.38077412
117DYRK1B0.37979538
118KSR10.37615789
119RPS6KB10.36542287
120IRAK30.36445046
121TAOK10.36293280
122RPS6KA30.34714519
123ADRBK10.34390916
124PRKCI0.31181511
125STK110.30687564
126CSNK1A1L0.30410201
127PHKG20.30254384
128PHKG10.30254384
129CDK30.29930392
130MAPK100.29617139

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049506.36992212
2Insulin secretion_Homo sapiens_hsa049113.62549396
3Protein export_Homo sapiens_hsa030602.77746896
4Synaptic vesicle cycle_Homo sapiens_hsa047212.67316174
5Vitamin B6 metabolism_Homo sapiens_hsa007502.52404649
6Type II diabetes mellitus_Homo sapiens_hsa049302.35512721
7Amphetamine addiction_Homo sapiens_hsa050312.19603869
8GABAergic synapse_Homo sapiens_hsa047272.12483582
9Taste transduction_Homo sapiens_hsa047422.09088778
10Circadian entrainment_Homo sapiens_hsa047132.08036221
11Cocaine addiction_Homo sapiens_hsa050302.07767884
12Type I diabetes mellitus_Homo sapiens_hsa049402.06100099
13Nicotine addiction_Homo sapiens_hsa050332.03052457
14Vibrio cholerae infection_Homo sapiens_hsa051101.96436735
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.88409523
16Morphine addiction_Homo sapiens_hsa050321.85876667
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.82110025
18Dopaminergic synapse_Homo sapiens_hsa047281.78138551
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.77342930
20Long-term potentiation_Homo sapiens_hsa047201.75366586
21Serotonergic synapse_Homo sapiens_hsa047261.68627730
22Glutamatergic synapse_Homo sapiens_hsa047241.68423946
23Olfactory transduction_Homo sapiens_hsa047401.68342629
24Cholinergic synapse_Homo sapiens_hsa047251.61599866
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51689695
26Sulfur metabolism_Homo sapiens_hsa009201.51682360
27Collecting duct acid secretion_Homo sapiens_hsa049661.50968199
28Carbohydrate digestion and absorption_Homo sapiens_hsa049731.44140787
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43680660
30Pancreatic secretion_Homo sapiens_hsa049721.28114192
31Renin secretion_Homo sapiens_hsa049241.25138623
32Salivary secretion_Homo sapiens_hsa049701.23144575
33Gastric acid secretion_Homo sapiens_hsa049711.19654483
34Long-term depression_Homo sapiens_hsa047301.14746178
35SNARE interactions in vesicular transport_Homo sapiens_hsa041301.14560825
36Circadian rhythm_Homo sapiens_hsa047101.04965355
37Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.02372944
38Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.98117404
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97858874
40cAMP signaling pathway_Homo sapiens_hsa040240.97763816
41Calcium signaling pathway_Homo sapiens_hsa040200.96587544
42Thyroid hormone synthesis_Homo sapiens_hsa049180.95601867
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94249441
44Estrogen signaling pathway_Homo sapiens_hsa049150.93196717
45Regulation of autophagy_Homo sapiens_hsa041400.92481082
46Glucagon signaling pathway_Homo sapiens_hsa049220.92235977
47Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91506786
48Prion diseases_Homo sapiens_hsa050200.88139978
49N-Glycan biosynthesis_Homo sapiens_hsa005100.87709348
50Oxytocin signaling pathway_Homo sapiens_hsa049210.87538293
51Bile secretion_Homo sapiens_hsa049760.86179374
52GnRH signaling pathway_Homo sapiens_hsa049120.85876822
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.85702235
54Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.85646436
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83239307
56Lysosome_Homo sapiens_hsa041420.81599305
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79318359
58Gap junction_Homo sapiens_hsa045400.75506243
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71489594
60Glycosaminoglycan degradation_Homo sapiens_hsa005310.69858622
61Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68875076
62Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68051947
63Alcoholism_Homo sapiens_hsa050340.67380707
64Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.67348868
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66622043
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64920389
67Prolactin signaling pathway_Homo sapiens_hsa049170.64489933
68Melanogenesis_Homo sapiens_hsa049160.63997107
69Oocyte meiosis_Homo sapiens_hsa041140.63742021
70Sphingolipid metabolism_Homo sapiens_hsa006000.61781489
71Dorso-ventral axis formation_Homo sapiens_hsa043200.60530818
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59341772
73Phototransduction_Homo sapiens_hsa047440.57298767
74Arginine biosynthesis_Homo sapiens_hsa002200.55401841
75Inositol phosphate metabolism_Homo sapiens_hsa005620.55358952
76ABC transporters_Homo sapiens_hsa020100.54968018
77VEGF signaling pathway_Homo sapiens_hsa043700.53465688
78Other glycan degradation_Homo sapiens_hsa005110.52594366
79Sulfur relay system_Homo sapiens_hsa041220.52445517
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.51628661
81Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.50323405
82Alzheimers disease_Homo sapiens_hsa050100.50319660
83ErbB signaling pathway_Homo sapiens_hsa040120.48506775
84mTOR signaling pathway_Homo sapiens_hsa041500.48196968
85beta-Alanine metabolism_Homo sapiens_hsa004100.47191942
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.46733066
87Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46587573
88Cardiac muscle contraction_Homo sapiens_hsa042600.45538491
89Insulin signaling pathway_Homo sapiens_hsa049100.43242813
90Endocytosis_Homo sapiens_hsa041440.42329862
91Oxidative phosphorylation_Homo sapiens_hsa001900.41950541
92Glioma_Homo sapiens_hsa052140.40540127
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.40457881
94Ovarian steroidogenesis_Homo sapiens_hsa049130.40411015
95Mineral absorption_Homo sapiens_hsa049780.40367974
96Axon guidance_Homo sapiens_hsa043600.40099642
97MAPK signaling pathway_Homo sapiens_hsa040100.39849107
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.39654298
99Ether lipid metabolism_Homo sapiens_hsa005650.38943794
100Rheumatoid arthritis_Homo sapiens_hsa053230.36972018
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36946371
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.35642462
103Ras signaling pathway_Homo sapiens_hsa040140.35116343
104Insulin resistance_Homo sapiens_hsa049310.34731556
105Rap1 signaling pathway_Homo sapiens_hsa040150.34531347
106Histidine metabolism_Homo sapiens_hsa003400.33331112
107Arginine and proline metabolism_Homo sapiens_hsa003300.33310967
108AMPK signaling pathway_Homo sapiens_hsa041520.32682658
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.31822579
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.30301394
111Linoleic acid metabolism_Homo sapiens_hsa005910.30127832
112Dilated cardiomyopathy_Homo sapiens_hsa054140.28611729
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27639043
114Fatty acid biosynthesis_Homo sapiens_hsa000610.27603553
115Wnt signaling pathway_Homo sapiens_hsa043100.26416617
116Butanoate metabolism_Homo sapiens_hsa006500.25397340
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.25210088
118Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.24934794
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.23443403
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23146700
121Phagosome_Homo sapiens_hsa041450.22557251

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