WASF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vocalization behavior (GO:0071625)5.63183015
2regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.57579662
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.49354447
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.46572222
5ionotropic glutamate receptor signaling pathway (GO:0035235)5.45794757
6locomotory exploration behavior (GO:0035641)5.27680266
7neuron cell-cell adhesion (GO:0007158)5.24546269
8protein localization to synapse (GO:0035418)5.21899851
9regulation of glutamate receptor signaling pathway (GO:1900449)5.08910924
10synaptic vesicle exocytosis (GO:0016079)5.08063287
11glutamate receptor signaling pathway (GO:0007215)5.04073542
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.89955268
13glutamate secretion (GO:0014047)4.80795976
14synaptic vesicle maturation (GO:0016188)4.70894701
15exploration behavior (GO:0035640)4.67886178
16regulation of long-term neuronal synaptic plasticity (GO:0048169)4.64735773
17regulation of synaptic vesicle exocytosis (GO:2000300)4.61237669
18synaptic transmission, glutamatergic (GO:0035249)4.57798109
19neuron recognition (GO:0008038)4.54471511
20neuronal action potential propagation (GO:0019227)4.49870475
21regulation of neuronal synaptic plasticity (GO:0048168)4.49282128
22regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.42915503
23synaptic vesicle docking involved in exocytosis (GO:0016081)4.36471321
24neuron-neuron synaptic transmission (GO:0007270)4.35554619
25pyrimidine nucleobase catabolic process (GO:0006208)4.26359061
26regulation of synaptic vesicle transport (GO:1902803)4.23616303
27dendritic spine morphogenesis (GO:0060997)4.17910551
28regulation of dendritic spine morphogenesis (GO:0061001)4.17152855
29positive regulation of synapse maturation (GO:0090129)4.12920600
30axonal fasciculation (GO:0007413)4.12587909
31regulation of excitatory postsynaptic membrane potential (GO:0060079)4.12083609
32establishment of mitochondrion localization (GO:0051654)4.11774254
33gamma-aminobutyric acid signaling pathway (GO:0007214)4.04825044
34neurotransmitter-gated ion channel clustering (GO:0072578)4.04107502
35regulation of synaptic plasticity (GO:0048167)3.94005724
36long-term memory (GO:0007616)3.93700445
37long-term synaptic potentiation (GO:0060291)3.89227164
38regulation of postsynaptic membrane potential (GO:0060078)3.89122921
39presynaptic membrane assembly (GO:0097105)3.87389339
40layer formation in cerebral cortex (GO:0021819)3.85695929
41neurotransmitter secretion (GO:0007269)3.75712019
42postsynaptic membrane organization (GO:0001941)3.74302702
43regulation of synapse structural plasticity (GO:0051823)3.74256066
44behavioral fear response (GO:0001662)3.72772303
45behavioral defense response (GO:0002209)3.72772303
46positive regulation of membrane potential (GO:0045838)3.69864804
47dendritic spine organization (GO:0097061)3.69754812
48positive regulation of dendritic spine morphogenesis (GO:0061003)3.68487697
49transmission of nerve impulse (GO:0019226)3.68323644
50synaptic vesicle endocytosis (GO:0048488)3.67740797
51G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.65167215
52presynaptic membrane organization (GO:0097090)3.64959502
53negative regulation of synaptic transmission, GABAergic (GO:0032229)3.61765514
54G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.61730732
55regulation of dendritic spine development (GO:0060998)3.58462030
56positive regulation of dendritic spine development (GO:0060999)3.51061707
57positive regulation of neurotransmitter secretion (GO:0001956)3.49781683
58fear response (GO:0042596)3.48689090
59nucleobase catabolic process (GO:0046113)3.48051656
60innervation (GO:0060384)3.43708211
61response to histamine (GO:0034776)3.42035810
62regulation of glutamate secretion (GO:0014048)3.36706504
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.36623428
64learning (GO:0007612)3.34394306
65regulation of female receptivity (GO:0045924)3.33803167
66membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.32587504
67gamma-aminobutyric acid transport (GO:0015812)3.29059916
68cellular potassium ion homeostasis (GO:0030007)3.28626533
69regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.28417694
70regulation of vesicle fusion (GO:0031338)3.27723169
71positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.25048090
72regulation of neurotransmitter secretion (GO:0046928)3.21160568
73negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.21117310
74long term synaptic depression (GO:0060292)3.20200781
75regulation of synapse maturation (GO:0090128)3.18120863
76establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.17070533
77mitochondrion transport along microtubule (GO:0047497)3.17070533
78proline transport (GO:0015824)3.16954226
79membrane depolarization (GO:0051899)3.16541214
80neuromuscular process controlling balance (GO:0050885)3.14554845
81neurotransmitter transport (GO:0006836)3.14410649
82auditory behavior (GO:0031223)3.11630411
83positive regulation of neurotransmitter transport (GO:0051590)3.10162971
84central nervous system projection neuron axonogenesis (GO:0021952)3.09641401
85regulation of synaptic transmission (GO:0050804)3.08137794
86chemosensory behavior (GO:0007635)3.05413629
87female mating behavior (GO:0060180)3.04666579
88regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.02797929
89sodium ion export (GO:0071436)3.02734862
90positive regulation of synaptic transmission, GABAergic (GO:0032230)3.01243368
91startle response (GO:0001964)2.99378176
92positive regulation of synaptic transmission (GO:0050806)2.99252915
93synapse assembly (GO:0007416)2.99095656
94vesicle transport along microtubule (GO:0047496)2.98586642
95positive regulation of mitochondrial fission (GO:0090141)2.97869157
96positive regulation of synapse assembly (GO:0051965)2.95470598
97dendrite morphogenesis (GO:0048813)2.95369603
98neuronal ion channel clustering (GO:0045161)2.94823804
99behavioral response to cocaine (GO:0048148)2.93847723
100synaptic transmission (GO:0007268)2.93791551
101cochlea development (GO:0090102)2.93489476
102positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.92551399
103social behavior (GO:0035176)2.91103059
104intraspecies interaction between organisms (GO:0051703)2.91103059
105cell migration in hindbrain (GO:0021535)2.91019363
106regulation of neurotransmitter transport (GO:0051588)2.91001894
107regulation of neurotransmitter levels (GO:0001505)2.89201127
108cerebellar granule cell differentiation (GO:0021707)2.88665101
109mechanosensory behavior (GO:0007638)2.84788059
110adult walking behavior (GO:0007628)2.81104106
111regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.79458493
112synaptic vesicle transport (GO:0048489)2.77709543
113establishment of synaptic vesicle localization (GO:0097480)2.77709543
114neuromuscular synaptic transmission (GO:0007274)2.74102313
115piRNA metabolic process (GO:0034587)2.73733134
116cerebellar Purkinje cell differentiation (GO:0021702)2.67777222
117response to auditory stimulus (GO:0010996)2.67055132
118regulation of voltage-gated calcium channel activity (GO:1901385)2.66224275
119hippocampus development (GO:0021766)2.58153494
120axon ensheathment in central nervous system (GO:0032291)2.57933163
121central nervous system myelination (GO:0022010)2.57933163
122establishment of vesicle localization (GO:0051650)2.55842702
123acidic amino acid transport (GO:0015800)2.55275820
124neurofilament cytoskeleton organization (GO:0060052)2.54731404
125synapse organization (GO:0050808)2.54565933
126regulation of synapse assembly (GO:0051963)2.53909279
127glycosphingolipid biosynthetic process (GO:0006688)2.52796265
128negative regulation of dendrite morphogenesis (GO:0050774)2.51380772

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.51782182
2GBX2_23144817_ChIP-Seq_PC3_Human4.08169137
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.23308274
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.20608903
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.09398084
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.74723216
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.74723216
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.74264017
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.70846429
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.66538342
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.63209065
12RARB_27405468_Chip-Seq_BRAIN_Mouse2.59711729
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.58284757
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50888061
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46155547
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.40605442
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.39512627
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.26381508
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.19581731
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18673808
21* REST_18959480_ChIP-ChIP_MESCs_Mouse2.14788696
22DROSHA_22980978_ChIP-Seq_HELA_Human2.13893800
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.07964020
24CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04468556
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.99785234
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98629082
27TAF15_26573619_Chip-Seq_HEK293_Human1.96038993
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.94241914
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.92128103
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.90381275
31AR_21572438_ChIP-Seq_LNCaP_Human1.82869458
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.76185069
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.72956888
34SMAD4_21799915_ChIP-Seq_A2780_Human1.71450579
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.68124807
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.64504858
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.62899958
38ZNF274_21170338_ChIP-Seq_K562_Hela1.62170278
39P300_19829295_ChIP-Seq_ESCs_Human1.60649051
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54351131
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.54239978
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.50919262
43EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49968190
44VDR_22108803_ChIP-Seq_LS180_Human1.49630301
45GATA1_26923725_Chip-Seq_HPCs_Mouse1.48137217
46FUS_26573619_Chip-Seq_HEK293_Human1.47820083
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.45347061
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.42876037
49ERG_21242973_ChIP-ChIP_JURKAT_Human1.41538175
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40785277
51* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.40703648
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39900061
53HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38415096
54* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36320336
55TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36072205
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35552351
57GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34075565
58SALL1_21062744_ChIP-ChIP_HESCs_Human1.32180840
59AR_25329375_ChIP-Seq_VCAP_Human1.31912172
60SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31711825
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.31429137
62* RING1B_27294783_Chip-Seq_ESCs_Mouse1.30681735
63* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.28957544
64SOX2_21211035_ChIP-Seq_LN229_Gbm1.27371754
65RNF2_27304074_Chip-Seq_NSC_Mouse1.25784046
66E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.23575593
67STAT3_23295773_ChIP-Seq_U87_Human1.22114688
68MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.22054930
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.20771994
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.19873406
71TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18950367
72IGF1R_20145208_ChIP-Seq_DFB_Human1.17295430
73* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.16889454
74UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15752840
75AR_19668381_ChIP-Seq_PC3_Human1.14624957
76TP53_16413492_ChIP-PET_HCT116_Human1.14490563
77* PRDM14_20953172_ChIP-Seq_ESCs_Human1.10519484
78TCF4_23295773_ChIP-Seq_U87_Human1.10003001
79WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09920871
80CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.09867562
81EWS_26573619_Chip-Seq_HEK293_Human1.09766550
82ARNT_22903824_ChIP-Seq_MCF-7_Human1.09086150
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08676934
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06558447
85YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06036210
86* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05706464
87JUN_21703547_ChIP-Seq_K562_Human1.05642034
88RUNX2_22187159_ChIP-Seq_PCA_Human1.03689758
89MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03417531
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01730161
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01730161
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01658518
93MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01632070
94MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00933584
95ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00742302
96TP53_18474530_ChIP-ChIP_U2OS_Human0.99463801
97* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99221592
98* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98886167
99AHR_22903824_ChIP-Seq_MCF-7_Human0.98744207
100REST_19997604_ChIP-ChIP_NEURONS_Mouse0.98612775
101NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97769571
102TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96216248
103OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.95705226
104CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95596378
105POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95173831
106ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.93401047
107NANOG_18555785_Chip-Seq_ESCs_Mouse0.93183205
108CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.93165532
109KLF5_20875108_ChIP-Seq_MESCs_Mouse0.91884352
110SMAD3_21741376_ChIP-Seq_ESCs_Human0.91842766
111TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91450368
112CDX2_19796622_ChIP-Seq_MESCs_Mouse0.91188327
113KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.90952436
114RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90821793
115TET1_21490601_ChIP-Seq_MESCs_Mouse0.90795737
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.90732911
117* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90556425
118SMAD_19615063_ChIP-ChIP_OVARY_Human0.89970138
119RUNX1_26923725_Chip-Seq_HPCs_Mouse0.89393940
120* SOX9_26525672_Chip-Seq_HEART_Mouse0.89304245
121DNAJC2_21179169_ChIP-ChIP_NT2_Human0.89247356
122ER_23166858_ChIP-Seq_MCF-7_Human0.88069993
123* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87622122
124* THAP11_20581084_ChIP-Seq_MESCs_Mouse0.87181342
125SOX2_16153702_ChIP-ChIP_HESCs_Human0.86555936
126CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.85881269
127CBP_20019798_ChIP-Seq_JUKART_Human0.85494434
128IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.85494434

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.68917534
2MP0003880_abnormal_central_pattern6.04243880
3* MP0003635_abnormal_synaptic_transmissio4.16078120
4MP0004270_analgesia3.85116227
5* MP0002063_abnormal_learning/memory/cond3.48037680
6MP0009745_abnormal_behavioral_response3.47582935
7MP0002064_seizures3.09404454
8MP0001968_abnormal_touch/_nociception3.01989102
9* MP0002572_abnormal_emotion/affect_behav2.83208059
10MP0002736_abnormal_nociception_after2.59658480
11MP0002272_abnormal_nervous_system2.57797835
12MP0009046_muscle_twitch2.53234502
13MP0001486_abnormal_startle_reflex2.48907897
14MP0002734_abnormal_mechanical_nocicepti2.42254963
15MP0001440_abnormal_grooming_behavior2.36981808
16MP0002735_abnormal_chemical_nociception2.35944311
17MP0005423_abnormal_somatic_nervous2.31591185
18MP0001501_abnormal_sleep_pattern2.26922304
19MP0002822_catalepsy2.16190961
20MP0003329_amyloid_beta_deposits2.12082232
21* MP0000778_abnormal_nervous_system2.09903070
22MP0002733_abnormal_thermal_nociception1.91685830
23MP0002067_abnormal_sensory_capabilities1.90223544
24MP0002184_abnormal_innervation1.86278485
25MP0001529_abnormal_vocalization1.85038076
26MP0006276_abnormal_autonomic_nervous1.84034646
27MP0001970_abnormal_pain_threshold1.82020795
28MP0009780_abnormal_chondrocyte_physiolo1.79625288
29MP0002557_abnormal_social/conspecific_i1.67584264
30MP0005386_behavior/neurological_phenoty1.64538654
31MP0004924_abnormal_behavior1.64538654
32MP0003121_genomic_imprinting1.59835598
33* MP0004811_abnormal_neuron_physiology1.59828886
34MP0004858_abnormal_nervous_system1.59288567
35MP0000955_abnormal_spinal_cord1.57854843
36MP0003787_abnormal_imprinting1.51460758
37MP0008569_lethality_at_weaning1.50955965
38MP0008789_abnormal_olfactory_epithelium1.50766145
39* MP0002882_abnormal_neuron_morphology1.43284709
40MP0001188_hyperpigmentation1.42975221
41MP0004885_abnormal_endolymph1.41284134
42MP0003879_abnormal_hair_cell1.40766582
43* MP0002066_abnormal_motor_capabilities/c1.38252989
44MP0001984_abnormal_olfaction1.38060693
45MP0002909_abnormal_adrenal_gland1.37589741
46MP0001905_abnormal_dopamine_level1.36327686
47MP0005646_abnormal_pituitary_gland1.34297817
48MP0002837_dystrophic_cardiac_calcinosis1.22799465
49* MP0002152_abnormal_brain_morphology1.19573256
50MP0001502_abnormal_circadian_rhythm1.15116561
51MP0004145_abnormal_muscle_electrophysio1.13565868
52MP0002653_abnormal_ependyma_morphology1.12379734
53MP0003633_abnormal_nervous_system1.10509143
54MP0005645_abnormal_hypothalamus_physiol1.07452983
55MP0004142_abnormal_muscle_tone1.07221445
56MP0003698_abnormal_male_reproductive1.05071941
57MP0003631_nervous_system_phenotype1.04330925
58MP0004742_abnormal_vestibular_system1.04110320
59MP0003122_maternal_imprinting1.03221088
60MP0002638_abnormal_pupillary_reflex1.03209964
61MP0000049_abnormal_middle_ear1.01983690
62MP0006292_abnormal_olfactory_placode0.98814136
63MP0005409_darkened_coat_color0.98142577
64MP0001963_abnormal_hearing_physiology0.93670644
65MP0002210_abnormal_sex_determination0.92610840
66MP0005394_taste/olfaction_phenotype0.92586680
67MP0005499_abnormal_olfactory_system0.92586680
68MP0002160_abnormal_reproductive_system0.90625450
69MP0000604_amyloidosis0.89672404
70MP0000751_myopathy0.89661688
71MP0001485_abnormal_pinna_reflex0.88785990
72MP0002229_neurodegeneration0.88179951
73* MP0002069_abnormal_eating/drinking_beha0.87465042
74MP0004147_increased_porphyrin_level0.85161405
75MP0000631_abnormal_neuroendocrine_gland0.84643493
76MP0005551_abnormal_eye_electrophysiolog0.83794408
77MP0003632_abnormal_nervous_system0.83739434
78MP0004484_altered_response_of0.83653081
79MP0002751_abnormal_autonomic_nervous0.83509018
80MP0001929_abnormal_gametogenesis0.83056472
81MP0002752_abnormal_somatic_nervous0.82962396
82MP0004085_abnormal_heartbeat0.80195164
83MP0002233_abnormal_nose_morphology0.78586579
84MP0008872_abnormal_physiological_respon0.77701235
85MP0008874_decreased_physiological_sensi0.77440855
86MP0003634_abnormal_glial_cell0.77276367
87MP0001299_abnormal_eye_distance/0.77101059
88* MP0003861_abnormal_nervous_system0.76770189
89MP0004133_heterotaxia0.76295397
90MP0010386_abnormal_urinary_bladder0.76287483
91MP0005253_abnormal_eye_physiology0.74423055
92MP0002249_abnormal_larynx_morphology0.72503172
93MP0000920_abnormal_myelination0.72233116
94MP0004215_abnormal_myocardial_fiber0.72122422
95MP0001177_atelectasis0.72087861
96MP0001145_abnormal_male_reproductive0.71908311
97MP0005171_absent_coat_pigmentation0.71530509
98MP0000653_abnormal_sex_gland0.71244765
99MP0003385_abnormal_body_wall0.70929856
100MP0003890_abnormal_embryonic-extraembry0.70359365
101MP0005535_abnormal_body_temperature0.69636626
102MP0002161_abnormal_fertility/fecundity0.68931081
103MP0002081_perinatal_lethality0.68896871
104MP0008058_abnormal_DNA_repair0.68816447
105MP0000026_abnormal_inner_ear0.68796429
106MP0002876_abnormal_thyroid_physiology0.68788082
107MP0000566_synostosis0.68634795
108MP0003937_abnormal_limbs/digits/tail_de0.67411773
109MP0002234_abnormal_pharynx_morphology0.67377308
110MP0004233_abnormal_muscle_weight0.67146203
111MP0003938_abnormal_ear_development0.67074710
112MP0001664_abnormal_digestion0.65938713
113MP0001293_anophthalmia0.65336515
114MP0008995_early_reproductive_senescence0.65119030
115MP0006072_abnormal_retinal_apoptosis0.64580338
116MP0005187_abnormal_penis_morphology0.63492214
117MP0005623_abnormal_meninges_morphology0.63447766
118MP0003075_altered_response_to0.62474599
119MP0003137_abnormal_impulse_conducting0.61295476
120MP0004510_myositis0.59074324
121MP0003283_abnormal_digestive_organ0.57331813
122MP0001943_abnormal_respiration0.55326829
123MP0000013_abnormal_adipose_tissue0.54394902
124MP0002102_abnormal_ear_morphology0.54358110
125MP0008877_abnormal_DNA_methylation0.54187447
126MP0003123_paternal_imprinting0.50077076
127* MP0010769_abnormal_survival0.49762797
128MP0003119_abnormal_digestive_system0.49298440

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.08700633
2Myokymia (HP:0002411)6.25272323
3Focal seizures (HP:0007359)5.77587591
4Epileptic encephalopathy (HP:0200134)5.19193647
5Visual hallucinations (HP:0002367)5.00298136
6Atonic seizures (HP:0010819)4.81002776
7Hyperventilation (HP:0002883)4.49161102
8Absence seizures (HP:0002121)4.35285239
9Febrile seizures (HP:0002373)4.33928836
10Dialeptic seizures (HP:0011146)4.06791975
11Progressive cerebellar ataxia (HP:0002073)3.88360100
12Broad-based gait (HP:0002136)3.78670211
13Cerebral inclusion bodies (HP:0100314)3.73360228
14Generalized tonic-clonic seizures (HP:0002069)3.73325029
15Amblyopia (HP:0000646)3.70546210
16Supranuclear gaze palsy (HP:0000605)3.65508696
17Neurofibrillary tangles (HP:0002185)3.33237566
18Poor eye contact (HP:0000817)3.32216873
19Drooling (HP:0002307)3.23466276
20Excessive salivation (HP:0003781)3.23466276
21Action tremor (HP:0002345)3.19653966
22Impaired vibration sensation in the lower limbs (HP:0002166)3.18776824
23Dysmetria (HP:0001310)3.09559844
24Gaze-evoked nystagmus (HP:0000640)2.98589567
25Dysdiadochokinesis (HP:0002075)2.96753226
26Impaired social interactions (HP:0000735)2.92431048
27Abnormal social behavior (HP:0012433)2.92431048
28Absent speech (HP:0001344)2.88151836
29Abnormality of the lower motor neuron (HP:0002366)2.87571712
30Truncal ataxia (HP:0002078)2.87201606
31Anxiety (HP:0000739)2.82471173
32Epileptiform EEG discharges (HP:0011182)2.81486892
33Depression (HP:0000716)2.77447082
34Termporal pattern (HP:0011008)2.71525649
35Insidious onset (HP:0003587)2.71525649
36Hemiparesis (HP:0001269)2.69347479
37Abnormality of the labia minora (HP:0012880)2.65493850
38Urinary bladder sphincter dysfunction (HP:0002839)2.61842533
39Abnormality of the corticospinal tract (HP:0002492)2.60499171
40Ankle clonus (HP:0011448)2.56681001
41EEG with generalized epileptiform discharges (HP:0011198)2.55572095
42Cerebral hypomyelination (HP:0006808)2.54185977
43Delusions (HP:0000746)2.53036021
44Diplopia (HP:0000651)2.52839278
45Abnormality of binocular vision (HP:0011514)2.52839278
46Abnormal eating behavior (HP:0100738)2.51477090
47Impaired smooth pursuit (HP:0007772)2.48140006
48Congenital primary aphakia (HP:0007707)2.43810472
49Stereotypic behavior (HP:0000733)2.43529602
50Urinary urgency (HP:0000012)2.40809975
51Nephrogenic diabetes insipidus (HP:0009806)2.38647403
52Mutism (HP:0002300)2.38146997
53Amyotrophic lateral sclerosis (HP:0007354)2.38049518
54Atrophy/Degeneration involving motor neurons (HP:0007373)2.35878861
55Hypsarrhythmia (HP:0002521)2.35449606
56Spastic gait (HP:0002064)2.33468334
57Scanning speech (HP:0002168)2.33366341
58Inability to walk (HP:0002540)2.32709352
59Oligodactyly (hands) (HP:0001180)2.31846001
60Postural instability (HP:0002172)2.31499859
61Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.29199780
62Degeneration of the lateral corticospinal tracts (HP:0002314)2.29199780
63Cortical dysplasia (HP:0002539)2.28913465
64Genetic anticipation (HP:0003743)2.27542889
65Progressive inability to walk (HP:0002505)2.26287239
66Split foot (HP:0001839)2.25482426
67Medial flaring of the eyebrow (HP:0010747)2.25434455
68Protruding tongue (HP:0010808)2.24862694
69Bradykinesia (HP:0002067)2.22113886
70Fetal akinesia sequence (HP:0001989)2.21398901
71Generalized myoclonic seizures (HP:0002123)2.19268029
72Thickened helices (HP:0000391)2.16472123
73Abnormality of salivation (HP:0100755)2.15642372
74Morphological abnormality of the pyramidal tract (HP:0002062)2.14567610
75Megalencephaly (HP:0001355)2.10097247
76Spastic tetraplegia (HP:0002510)2.09665587
77Lower limb muscle weakness (HP:0007340)2.05529669
78Lissencephaly (HP:0001339)2.05526195
79Abnormality of ocular smooth pursuit (HP:0000617)2.05265680
80Peripheral hypomyelination (HP:0007182)2.04140214
81Failure to thrive in infancy (HP:0001531)2.03892325
82Impaired vibratory sensation (HP:0002495)2.03851803
83Genital tract atresia (HP:0001827)2.03011540
84Hydroureter (HP:0000072)2.02642565
85Vaginal atresia (HP:0000148)1.99823684
86Focal dystonia (HP:0004373)1.98509253
87Torticollis (HP:0000473)1.98475417
88CNS hypomyelination (HP:0003429)1.97510487
89Status epilepticus (HP:0002133)1.96582533
90Oligodactyly (HP:0012165)1.96260616
91Blue irides (HP:0000635)1.92689016
92Intention tremor (HP:0002080)1.92619261
93Incomplete penetrance (HP:0003829)1.92243005
94Hypoplasia of the brainstem (HP:0002365)1.91761209
95Aplasia/Hypoplasia of the brainstem (HP:0007362)1.91761209
96Polyphagia (HP:0002591)1.91200899
97Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.89787684
98Retinal dysplasia (HP:0007973)1.88562190
99Papilledema (HP:0001085)1.86814249
100Gait imbalance (HP:0002141)1.85638363
101Poor suck (HP:0002033)1.85543645
102Gait ataxia (HP:0002066)1.85311299
103Inappropriate behavior (HP:0000719)1.82524176
104Deep palmar crease (HP:0006191)1.81603309
105Shoulder girdle muscle weakness (HP:0003547)1.80395212
106Obstructive sleep apnea (HP:0002870)1.80142810
107Gastroesophageal reflux (HP:0002020)1.79540068
108Poor coordination (HP:0002370)1.78898357
109Psychosis (HP:0000709)1.77572671
110Rapidly progressive (HP:0003678)1.76870331
111Widely spaced teeth (HP:0000687)1.76284954
112Autism (HP:0000717)1.76085762
113Lower limb asymmetry (HP:0100559)1.75779169
114Hypoplasia of the corpus callosum (HP:0002079)1.73419268
115Esotropia (HP:0000565)1.71541591
116Annular pancreas (HP:0001734)1.70894290
117Sleep apnea (HP:0010535)1.70840615
118Paraplegia (HP:0010550)1.70554030
119Apathy (HP:0000741)1.69626199
120Volvulus (HP:0002580)1.69247536
121Dyskinesia (HP:0100660)1.68964746
122Limb dystonia (HP:0002451)1.68740911
123Hand muscle atrophy (HP:0009130)1.67736727
124Clonus (HP:0002169)1.67413754
125Pointed chin (HP:0000307)1.67024724
126Akinesia (HP:0002304)1.66684393
127Pheochromocytoma (HP:0002666)1.66232648
128Specific learning disability (HP:0001328)1.66173753
129Craniofacial dystonia (HP:0012179)1.65989281
130Insomnia (HP:0100785)1.65066730
131Spastic paraplegia (HP:0001258)1.64415009
132Lower limb amyotrophy (HP:0007210)1.63428188
133Pachygyria (HP:0001302)1.62246357
134Hepatoblastoma (HP:0002884)1.62061144
135Broad foot (HP:0001769)1.60652138
136Nephronophthisis (HP:0000090)1.59125606
137Rimmed vacuoles (HP:0003805)1.58251250
138Supernumerary spleens (HP:0009799)1.55374874
139Muscular hypotonia of the trunk (HP:0008936)1.54213978
140Tubulointerstitial nephritis (HP:0001970)1.53928709
141Abnormality of the motor neurons (HP:0002450)1.52496188
142Abnormal neuron morphology (HP:0012757)1.52496188

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.63189612
2NTRK34.58925362
3MAP3K93.37479907
4RIPK43.26247098
5MAP3K42.78238601
6MARK12.68832568
7CASK2.58920809
8MINK12.57665581
9MAP2K72.34262665
10DAPK22.17064692
11PNCK2.16052449
12KSR12.12687462
13PLK22.11991049
14KSR22.11976840
15MAP3K122.00060580
16TRIM281.97764428
17PAK61.92210081
18DAPK11.75351814
19MAP2K41.66533177
20ARAF1.65643515
21BMPR21.63468845
22NTRK21.62571320
23SIK21.60650895
24PRPF4B1.59812001
25NTRK11.55559463
26SRPK11.50998552
27PRKD31.47325429
28GRK51.45491517
29TNIK1.43488919
30CSNK1G31.43448268
31MAP4K21.39622856
32PTK2B1.37719361
33* CDK51.37268935
34CSNK1A1L1.34837311
35MAP3K131.29872295
36FES1.28982955
37CDK191.27217780
38PRKCG1.24363504
39TYRO31.22443542
40MAPK131.19938359
41RAF11.18271693
42CAMK2A1.16572067
43CSNK1G11.12453726
44CAMKK11.11657816
45WNK31.11174899
46CAMK2B1.11082973
47NME11.08905484
48FGR1.05772289
49UHMK10.99579617
50LATS20.93875034
51PLK40.92557834
52ERBB30.90925879
53MAP3K20.90534707
54CDK180.89732570
55CDK140.87990736
56OXSR10.86590892
57DYRK1A0.85357441
58CDK150.85079498
59STK380.83065325
60BCKDK0.82879568
61BCR0.75801993
62CDK11A0.74419133
63BRSK10.70957830
64SGK4940.70753272
65SGK2230.70753272
66LIMK10.68643083
67SGK10.68390792
68DYRK30.68120126
69CAMK10.67587066
70TESK10.67388097
71PAK30.67145458
72BRD40.67000717
73DYRK1B0.66002169
74SIK30.65088291
75MET0.64235222
76MKNK10.63756575
77STK110.59440287
78BRAF0.57513212
79PRKCE0.55908128
80CAMK2D0.55854010
81AKT30.55699158
82FER0.55293859
83PHKG20.55110552
84PHKG10.55110552
85CSNK1G20.54151547
86RET0.53965102
87ROCK20.53619532
88MARK20.53524860
89CCNB10.52080153
90CAMK40.49864776
91PRKCZ0.49205900
92PLK30.49089337
93MAP3K60.47840407
94DMPK0.47328198
95STK390.46811248
96GRK60.46771372
97RPS6KA40.46754801
98SGK20.46154769
99CAMKK20.46112294
100PINK10.46087754
101PLK10.45277029
102MKNK20.44957323
103MAP2K10.43510136
104CAMK2G0.42950537
105PDPK10.42810704
106CDC70.42486652
107PDK10.41771466
108MAPK100.41506923
109CDK30.41420397
110FYN0.39570995
111CSNK1D0.37529377
112MAP3K10.37515397
113RPS6KA30.37349611
114TSSK60.36708770
115MAP3K50.36616635
116DAPK30.33452556
117EPHB20.32956620
118PRKCH0.32706035
119AURKA0.32215605
120NEK10.31586159
121NEK60.31310727
122TNK20.31228721
123MOS0.28987731
124CSNK1E0.28901368
125MAPK120.27363133
126DYRK20.27263024
127CAMK1G0.27048475
128PRKACA0.26864133
129PKN10.26561522
130MAP3K70.26127443
131PRKCB0.25940025

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.11968864
2Long-term potentiation_Homo sapiens_hsa047203.24091276
3Synaptic vesicle cycle_Homo sapiens_hsa047212.89393762
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.88060883
5Circadian entrainment_Homo sapiens_hsa047132.80942027
6Glutamatergic synapse_Homo sapiens_hsa047242.80693124
7Amphetamine addiction_Homo sapiens_hsa050312.78717490
8GABAergic synapse_Homo sapiens_hsa047272.55035540
9Olfactory transduction_Homo sapiens_hsa047402.53333943
10Morphine addiction_Homo sapiens_hsa050322.47556586
11Dopaminergic synapse_Homo sapiens_hsa047282.31986214
12Salivary secretion_Homo sapiens_hsa049702.31337091
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.15031578
14Long-term depression_Homo sapiens_hsa047301.96497946
15Renin secretion_Homo sapiens_hsa049241.91644201
16Gastric acid secretion_Homo sapiens_hsa049711.87538385
17Taste transduction_Homo sapiens_hsa047421.86886988
18Serotonergic synapse_Homo sapiens_hsa047261.83943804
19Cholinergic synapse_Homo sapiens_hsa047251.81312999
20Insulin secretion_Homo sapiens_hsa049111.80082906
21Oxytocin signaling pathway_Homo sapiens_hsa049211.79475074
22Calcium signaling pathway_Homo sapiens_hsa040201.76862520
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.75746651
24Collecting duct acid secretion_Homo sapiens_hsa049661.67618436
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60577760
26GnRH signaling pathway_Homo sapiens_hsa049121.50498891
27Cocaine addiction_Homo sapiens_hsa050301.48835865
28Axon guidance_Homo sapiens_hsa043601.48298203
29Gap junction_Homo sapiens_hsa045401.43492130
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33461380
31Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.29425371
32cAMP signaling pathway_Homo sapiens_hsa040241.27708148
33Steroid biosynthesis_Homo sapiens_hsa001001.27372172
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.26371742
35Melanogenesis_Homo sapiens_hsa049161.21782496
36Glioma_Homo sapiens_hsa052141.20646334
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17715623
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15893537
39Cardiac muscle contraction_Homo sapiens_hsa042601.14747275
40Estrogen signaling pathway_Homo sapiens_hsa049151.12522501
41cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11520402
42Oocyte meiosis_Homo sapiens_hsa041141.11431660
43Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.08729948
44Phototransduction_Homo sapiens_hsa047441.07334497
45Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.06486452
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05411891
47mRNA surveillance pathway_Homo sapiens_hsa030151.04663875
48ErbB signaling pathway_Homo sapiens_hsa040121.04050828
49Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.03438132
50Vibrio cholerae infection_Homo sapiens_hsa051101.02282854
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.99389276
52Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.95265971
53Alzheimers disease_Homo sapiens_hsa050100.94165373
54Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.92703032
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.91033232
56VEGF signaling pathway_Homo sapiens_hsa043700.86549032
57Type II diabetes mellitus_Homo sapiens_hsa049300.85753325
58Pancreatic secretion_Homo sapiens_hsa049720.84566567
59Hippo signaling pathway_Homo sapiens_hsa043900.81678039
60Regulation of autophagy_Homo sapiens_hsa041400.80810206
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.78998158
62Dorso-ventral axis formation_Homo sapiens_hsa043200.78622274
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.78361660
642-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77056871
65Butanoate metabolism_Homo sapiens_hsa006500.75752193
66Oxidative phosphorylation_Homo sapiens_hsa001900.72752242
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72734998
68* Choline metabolism in cancer_Homo sapiens_hsa052310.72640104
69RNA transport_Homo sapiens_hsa030130.70695942
70Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69635262
71Thyroid hormone synthesis_Homo sapiens_hsa049180.69427421
72MAPK signaling pathway_Homo sapiens_hsa040100.67493851
73African trypanosomiasis_Homo sapiens_hsa051430.65417127
74Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.65210622
75Glucagon signaling pathway_Homo sapiens_hsa049220.63588988
76Wnt signaling pathway_Homo sapiens_hsa043100.62644511
77Ras signaling pathway_Homo sapiens_hsa040140.62067680
78Dilated cardiomyopathy_Homo sapiens_hsa054140.60891352
79Rap1 signaling pathway_Homo sapiens_hsa040150.59506090
80Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.59486898
81Fanconi anemia pathway_Homo sapiens_hsa034600.58784247
82Base excision repair_Homo sapiens_hsa034100.57271509
83Vitamin B6 metabolism_Homo sapiens_hsa007500.57255190
84Arginine and proline metabolism_Homo sapiens_hsa003300.56919659
85RNA degradation_Homo sapiens_hsa030180.56417496
86Basal transcription factors_Homo sapiens_hsa030220.54878969
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.54022931
88Cell cycle_Homo sapiens_hsa041100.53760473
89Protein export_Homo sapiens_hsa030600.53631424
90Spliceosome_Homo sapiens_hsa030400.51629453
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.51306272
92Biosynthesis of amino acids_Homo sapiens_hsa012300.50699053
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49843419
94Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.49220306
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48380689
96Alcoholism_Homo sapiens_hsa050340.48139847
97Parkinsons disease_Homo sapiens_hsa050120.46229376
98Prion diseases_Homo sapiens_hsa050200.45909705
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45002479
100Fatty acid biosynthesis_Homo sapiens_hsa000610.44732524
101Renal cell carcinoma_Homo sapiens_hsa052110.44722805
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44477604
103Inositol phosphate metabolism_Homo sapiens_hsa005620.44034376
104Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.43828075
105AMPK signaling pathway_Homo sapiens_hsa041520.43286062
106Non-small cell lung cancer_Homo sapiens_hsa052230.43066769
107Huntingtons disease_Homo sapiens_hsa050160.41878932
108Propanoate metabolism_Homo sapiens_hsa006400.40932459
109Sulfur relay system_Homo sapiens_hsa041220.40641166
110Cysteine and methionine metabolism_Homo sapiens_hsa002700.40194686
111mTOR signaling pathway_Homo sapiens_hsa041500.40148883
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39269534
113Carbohydrate digestion and absorption_Homo sapiens_hsa049730.38858809
114Basal cell carcinoma_Homo sapiens_hsa052170.38748748
115Fatty acid elongation_Homo sapiens_hsa000620.38617646
116Ether lipid metabolism_Homo sapiens_hsa005650.37647214
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36365510
118Endocytosis_Homo sapiens_hsa041440.34198356
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32837484
120Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.32605471
121Endometrial cancer_Homo sapiens_hsa052130.31391588
122Circadian rhythm_Homo sapiens_hsa047100.31335620
123Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28327682
124Type I diabetes mellitus_Homo sapiens_hsa049400.25735200
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.25277007
126Colorectal cancer_Homo sapiens_hsa052100.25136795
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.24892504
128Hedgehog signaling pathway_Homo sapiens_hsa043400.24589162
129Tight junction_Homo sapiens_hsa045300.24191028
130Insulin signaling pathway_Homo sapiens_hsa049100.23710106
131Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.23436908
132* Regulation of actin cytoskeleton_Homo sapiens_hsa048100.22520891
133* Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.22425030

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