Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 4.60793760 |
2 | heterochromatin organization (GO:0070828) | 4.58390471 |
3 | nuclear pore complex assembly (GO:0051292) | 4.53461697 |
4 | nuclear pore organization (GO:0006999) | 4.46467427 |
5 | mitotic sister chromatid segregation (GO:0000070) | 4.42259147 |
6 | protein localization to kinetochore (GO:0034501) | 4.35187726 |
7 | protein localization to chromosome, centromeric region (GO:0071459) | 4.31589946 |
8 | establishment of integrated proviral latency (GO:0075713) | 4.15438136 |
9 | pre-miRNA processing (GO:0031054) | 4.14442196 |
10 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.10556146 |
11 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.10556146 |
12 | sister chromatid segregation (GO:0000819) | 4.06938310 |
13 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.03611579 |
14 | mitotic nuclear envelope disassembly (GO:0007077) | 3.99260436 |
15 | regulation of histone H3-K27 methylation (GO:0061085) | 3.96148186 |
16 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.91997530 |
17 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.89888467 |
18 | piRNA metabolic process (GO:0034587) | 3.82941806 |
19 | synaptonemal complex assembly (GO:0007130) | 3.78669928 |
20 | ribosome assembly (GO:0042255) | 3.77885401 |
21 | nuclear envelope disassembly (GO:0051081) | 3.76419546 |
22 | membrane disassembly (GO:0030397) | 3.76419546 |
23 | regulation of histone H3-K9 methylation (GO:0051570) | 3.76336643 |
24 | sperm-egg recognition (GO:0035036) | 3.75481196 |
25 | synaptonemal complex organization (GO:0070193) | 3.72412336 |
26 | binding of sperm to zona pellucida (GO:0007339) | 3.71314440 |
27 | mitotic sister chromatid cohesion (GO:0007064) | 3.67289742 |
28 | microtubule depolymerization (GO:0007019) | 3.64936288 |
29 | positive regulation of chromosome segregation (GO:0051984) | 3.64483060 |
30 | DNA replication initiation (GO:0006270) | 3.61457113 |
31 | DNA topological change (GO:0006265) | 3.60773000 |
32 | chromatin assembly (GO:0031497) | 3.60075749 |
33 | chromosome condensation (GO:0030261) | 3.51800988 |
34 | gene silencing by RNA (GO:0031047) | 3.49370856 |
35 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.48486922 |
36 | regulation of gene silencing by miRNA (GO:0060964) | 3.48486922 |
37 | regulation of gene silencing by RNA (GO:0060966) | 3.48486922 |
38 | ribosomal small subunit biogenesis (GO:0042274) | 3.45679399 |
39 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.45100491 |
40 | mitotic chromosome condensation (GO:0007076) | 3.44988279 |
41 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.44910271 |
42 | sperm motility (GO:0030317) | 3.43202081 |
43 | motile cilium assembly (GO:0044458) | 3.42618227 |
44 | cell-cell recognition (GO:0009988) | 3.40586272 |
45 | male meiosis (GO:0007140) | 3.38612127 |
46 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.36554995 |
47 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.36245827 |
48 | pore complex assembly (GO:0046931) | 3.35341936 |
49 | regulation of RNA export from nucleus (GO:0046831) | 3.33491218 |
50 | mRNA stabilization (GO:0048255) | 3.33020566 |
51 | RNA stabilization (GO:0043489) | 3.33020566 |
52 | telomere maintenance via recombination (GO:0000722) | 3.32521815 |
53 | DNA replication checkpoint (GO:0000076) | 3.30241938 |
54 | spermatid development (GO:0007286) | 3.27300372 |
55 | regulation of translational fidelity (GO:0006450) | 3.26892824 |
56 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.26363445 |
57 | DNA duplex unwinding (GO:0032508) | 3.25697835 |
58 | mRNA splicing, via spliceosome (GO:0000398) | 3.25077395 |
59 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.25077395 |
60 | DNA geometric change (GO:0032392) | 3.23972225 |
61 | negative regulation of histone methylation (GO:0031061) | 3.23836337 |
62 | acrosome assembly (GO:0001675) | 3.22668373 |
63 | gene silencing (GO:0016458) | 3.21078332 |
64 | RNA splicing, via transesterification reactions (GO:0000375) | 3.21035649 |
65 | protein localization to chromosome (GO:0034502) | 3.20993997 |
66 | DNA packaging (GO:0006323) | 3.20304638 |
67 | protein-DNA complex disassembly (GO:0032986) | 3.18773942 |
68 | nucleosome disassembly (GO:0006337) | 3.18773942 |
69 | axonemal dynein complex assembly (GO:0070286) | 3.17756665 |
70 | IMP biosynthetic process (GO:0006188) | 3.16849617 |
71 | DNA strand elongation (GO:0022616) | 3.16304970 |
72 | regulation of translational termination (GO:0006449) | 3.14975659 |
73 | ribosome biogenesis (GO:0042254) | 3.13447945 |
74 | mitotic recombination (GO:0006312) | 3.13107578 |
75 | mitotic metaphase plate congression (GO:0007080) | 3.12889055 |
76 | maturation of SSU-rRNA (GO:0030490) | 3.12740492 |
77 | dosage compensation (GO:0007549) | 3.12554860 |
78 | formation of translation preinitiation complex (GO:0001731) | 3.11978382 |
79 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.10532610 |
80 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.09097456 |
81 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.09097456 |
82 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.09097456 |
83 | regulation of chromosome segregation (GO:0051983) | 3.04909943 |
84 | IMP metabolic process (GO:0046040) | 3.04691567 |
85 | DNA conformation change (GO:0071103) | 3.04554638 |
86 | cellular protein complex localization (GO:0034629) | 3.04319709 |
87 | translesion synthesis (GO:0019985) | 3.03867110 |
88 | nuclear envelope organization (GO:0006998) | 3.01832925 |
89 | purine nucleobase biosynthetic process (GO:0009113) | 3.01421895 |
90 | negative regulation of mRNA processing (GO:0050686) | 3.00198177 |
91 | regulation of centrosome cycle (GO:0046605) | 2.99977277 |
92 | establishment of viral latency (GO:0019043) | 2.99975929 |
93 | regulation of cilium movement (GO:0003352) | 2.99562619 |
94 | negative regulation of mRNA metabolic process (GO:1903312) | 2.99015829 |
95 | ribosomal large subunit biogenesis (GO:0042273) | 2.99004972 |
96 | DNA synthesis involved in DNA repair (GO:0000731) | 2.98556336 |
97 | chromosome segregation (GO:0007059) | 2.98089783 |
98 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.98085552 |
99 | mRNA transport (GO:0051028) | 2.97483930 |
100 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.95674222 |
101 | regulation of mitotic spindle organization (GO:0060236) | 2.95522882 |
102 | chromatin silencing (GO:0006342) | 2.95126248 |
103 | chromosome organization involved in meiosis (GO:0070192) | 2.94311723 |
104 | chaperone-mediated protein complex assembly (GO:0051131) | 2.93951307 |
105 | histone H4-K12 acetylation (GO:0043983) | 2.93947988 |
106 | kinetochore organization (GO:0051383) | 2.92872502 |
107 | regulation of centriole replication (GO:0046599) | 2.92555578 |
108 | negative regulation of RNA splicing (GO:0033119) | 2.92098802 |
109 | DNA ligation (GO:0006266) | 2.91793721 |
110 | establishment of chromosome localization (GO:0051303) | 2.91413724 |
111 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.91133260 |
112 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.90702897 |
113 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.90702897 |
114 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.90221235 |
115 | regulation of sister chromatid cohesion (GO:0007063) | 2.89591213 |
116 | non-recombinational repair (GO:0000726) | 2.89401080 |
117 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.89401080 |
118 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.89214191 |
119 | meiotic nuclear division (GO:0007126) | 2.88876411 |
120 | regulation of spindle organization (GO:0090224) | 2.88567186 |
121 | nucleobase biosynthetic process (GO:0046112) | 2.88469375 |
122 | ribosomal small subunit assembly (GO:0000028) | 2.88367618 |
123 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.88346680 |
124 | histone arginine methylation (GO:0034969) | 2.87210988 |
125 | peptidyl-arginine N-methylation (GO:0035246) | 2.86687735 |
126 | peptidyl-arginine methylation (GO:0018216) | 2.86687735 |
127 | metaphase plate congression (GO:0051310) | 2.84337322 |
128 | rRNA transcription (GO:0009303) | 2.83827147 |
129 | ATP-dependent chromatin remodeling (GO:0043044) | 2.83821272 |
130 | protein complex localization (GO:0031503) | 2.83758770 |
131 | protein export from nucleus (GO:0006611) | 2.83419175 |
132 | multicellular organism reproduction (GO:0032504) | 2.83014306 |
133 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.82519317 |
134 | plasma membrane fusion (GO:0045026) | 2.82318268 |
135 | telomere maintenance via telomere lengthening (GO:0010833) | 2.81564208 |
136 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.81023611 |
137 | chromatin assembly or disassembly (GO:0006333) | 2.80420731 |
138 | RNA export from nucleus (GO:0006405) | 2.80209903 |
139 | epithelial cilium movement (GO:0003351) | 2.79111272 |
140 | mRNA export from nucleus (GO:0006406) | 2.78412330 |
141 | regulation of DNA endoreduplication (GO:0032875) | 2.78297078 |
142 | V(D)J recombination (GO:0033151) | 2.77815954 |
143 | regulation of meiosis I (GO:0060631) | 2.77764854 |
144 | translational initiation (GO:0006413) | 2.77067206 |
145 | regulation of mRNA stability (GO:0043488) | 2.76461277 |
146 | termination of RNA polymerase II transcription (GO:0006369) | 2.76367389 |
147 | DNA replication-independent nucleosome organization (GO:0034724) | 2.75904731 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.18095730 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.47666970 |
3 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 5.16948406 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.50534004 |
5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.20199914 |
6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.17282456 |
7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.02096181 |
8 | MYC_22102868_ChIP-Seq_BL_Human | 2.85485173 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.75092955 |
10 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.60501049 |
11 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.49735604 |
12 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.14707110 |
13 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.08471622 |
14 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.01006368 |
15 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.00097693 |
16 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.99505270 |
17 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.92094760 |
18 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.91345736 |
19 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.81690360 |
20 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.77729028 |
21 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.75182468 |
22 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.75043337 |
23 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.74177204 |
24 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.64592013 |
25 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.64592013 |
26 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.64592013 |
27 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.64497947 |
28 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.63578418 |
29 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.63261664 |
30 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61917549 |
31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59418714 |
32 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.59294027 |
33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.58716659 |
34 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54773641 |
35 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.54237033 |
36 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.53792473 |
37 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.50880918 |
38 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.50429254 |
39 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.49601779 |
40 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.49502589 |
41 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.47576650 |
42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.44775467 |
43 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.42480214 |
44 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.41360174 |
45 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.39478158 |
46 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.37915777 |
47 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.37078265 |
48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.36465461 |
49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.35665790 |
50 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.34914499 |
51 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.34417927 |
52 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.34071849 |
53 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.33063565 |
54 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.32950567 |
55 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.32286560 |
56 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.32126257 |
57 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.30634364 |
58 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.30133691 |
59 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.28961729 |
60 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.27525479 |
61 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.25908103 |
62 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.25320507 |
63 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.25172541 |
64 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.24722936 |
65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.24253653 |
66 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.23628468 |
67 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.22984382 |
68 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.22638281 |
69 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22507936 |
70 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.21139317 |
71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19838669 |
72 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.16379490 |
73 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15571904 |
74 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.15455110 |
75 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.13450820 |
76 | UTX_26944678_Chip-Seq_JUKART_Human | 1.13275818 |
77 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.11897510 |
78 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.11651110 |
79 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.11500884 |
80 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.11451982 |
81 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.10645307 |
82 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09797180 |
83 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.09042316 |
84 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07929181 |
85 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07179498 |
86 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07018250 |
87 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.04748185 |
88 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.01492897 |
89 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.01291386 |
90 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.00969364 |
91 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.00959024 |
92 | MAF_26560356_Chip-Seq_TH1_Human | 1.00513191 |
93 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.00403314 |
94 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.99821157 |
95 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.99362142 |
96 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.98013775 |
97 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.97988343 |
98 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.96588689 |
99 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.94444644 |
100 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93884820 |
101 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.92269541 |
102 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92052317 |
103 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91403136 |
104 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.91142307 |
105 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.90577780 |
106 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.90544025 |
107 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.90473757 |
108 | MAF_26560356_Chip-Seq_TH2_Human | 0.89466346 |
109 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.88088692 |
110 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.88057457 |
111 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.87971469 |
112 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.87020993 |
113 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.86758514 |
114 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.86616387 |
115 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.86534699 |
116 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.85458415 |
117 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.84879952 |
118 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.84864642 |
119 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.83734722 |
120 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.83440740 |
121 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.79933213 |
122 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.79428005 |
123 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76943367 |
124 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.76886263 |
125 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.75524154 |
126 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.74849530 |
127 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.74842320 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005410_abnormal_fertilization | 4.30205186 |
2 | MP0003111_abnormal_nucleus_morphology | 3.98396927 |
3 | MP0010094_abnormal_chromosome_stability | 3.69516146 |
4 | MP0008057_abnormal_DNA_replication | 3.65023334 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.57727810 |
6 | MP0003693_abnormal_embryo_hatching | 3.53842571 |
7 | MP0008877_abnormal_DNA_methylation | 3.46080234 |
8 | MP0003077_abnormal_cell_cycle | 3.17133891 |
9 | MP0001730_embryonic_growth_arrest | 2.63809123 |
10 | MP0003123_paternal_imprinting | 2.58743701 |
11 | MP0002653_abnormal_ependyma_morphology | 2.52051312 |
12 | MP0005076_abnormal_cell_differentiation | 2.42754555 |
13 | MP0001929_abnormal_gametogenesis | 2.28826360 |
14 | MP0010352_gastrointestinal_tract_polyps | 2.25255903 |
15 | MP0000350_abnormal_cell_proliferation | 2.23806879 |
16 | MP0003698_abnormal_male_reproductive | 2.14416595 |
17 | MP0008932_abnormal_embryonic_tissue | 2.05030476 |
18 | MP0010307_abnormal_tumor_latency | 2.01848284 |
19 | MP0008058_abnormal_DNA_repair | 2.01123358 |
20 | MP0005380_embryogenesis_phenotype | 2.00146271 |
21 | MP0001672_abnormal_embryogenesis/_devel | 2.00146271 |
22 | MP0008007_abnormal_cellular_replicative | 1.99057473 |
23 | MP0001697_abnormal_embryo_size | 1.98953920 |
24 | MP0002084_abnormal_developmental_patter | 1.97223605 |
25 | MP0002877_abnormal_melanocyte_morpholog | 1.96233472 |
26 | MP0002085_abnormal_embryonic_tissue | 1.95341950 |
27 | MP0002210_abnormal_sex_determination | 1.94624206 |
28 | MP0004197_abnormal_fetal_growth/weight/ | 1.86792212 |
29 | MP0002009_preneoplasia | 1.85294556 |
30 | MP0003984_embryonic_growth_retardation | 1.81908746 |
31 | MP0002088_abnormal_embryonic_growth/wei | 1.77836503 |
32 | MP0001145_abnormal_male_reproductive | 1.75512528 |
33 | MP0003121_genomic_imprinting | 1.72866959 |
34 | MP0002080_prenatal_lethality | 1.70343872 |
35 | MP0009278_abnormal_bone_marrow | 1.67696284 |
36 | MP0002086_abnormal_extraembryonic_tissu | 1.66840901 |
37 | MP0005623_abnormal_meninges_morphology | 1.59708858 |
38 | MP0000537_abnormal_urethra_morphology | 1.56469160 |
39 | MP0004233_abnormal_muscle_weight | 1.45843893 |
40 | MP0001849_ear_inflammation | 1.44347590 |
41 | MP0002396_abnormal_hematopoietic_system | 1.44287218 |
42 | MP0003119_abnormal_digestive_system | 1.42602028 |
43 | MP0003718_maternal_effect | 1.42087516 |
44 | MP0000653_abnormal_sex_gland | 1.41172895 |
45 | MP0004133_heterotaxia | 1.35597948 |
46 | MP0002161_abnormal_fertility/fecundity | 1.35304861 |
47 | MP0000313_abnormal_cell_death | 1.31410455 |
48 | MP0003786_premature_aging | 1.29094313 |
49 | MP0004808_abnormal_hematopoietic_stem | 1.25758012 |
50 | MP0003890_abnormal_embryonic-extraembry | 1.24093299 |
51 | MP0000490_abnormal_crypts_of | 1.20852750 |
52 | MP0000703_abnormal_thymus_morphology | 1.19238058 |
53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.17795529 |
54 | MP0002019_abnormal_tumor_incidence | 1.15777070 |
55 | MP0010030_abnormal_orbit_morphology | 1.10557597 |
56 | MP0005377_hearing/vestibular/ear_phenot | 1.09885273 |
57 | MP0003878_abnormal_ear_physiology | 1.09885273 |
58 | MP0005397_hematopoietic_system_phenotyp | 1.09124435 |
59 | MP0001545_abnormal_hematopoietic_system | 1.09124435 |
60 | MP0002163_abnormal_gland_morphology | 1.09117322 |
61 | MP0006035_abnormal_mitochondrial_morpho | 1.07938906 |
62 | MP0009672_abnormal_birth_weight | 1.07077602 |
63 | MP0003861_abnormal_nervous_system | 1.06096629 |
64 | MP0010234_abnormal_vibrissa_follicle | 1.05866220 |
65 | MP0003787_abnormal_imprinting | 1.04744342 |
66 | MP0009703_decreased_birth_body | 1.03345734 |
67 | MP0001293_anophthalmia | 1.01509688 |
68 | MP0001346_abnormal_lacrimal_gland | 1.01217157 |
69 | MP0009333_abnormal_splenocyte_physiolog | 0.98638357 |
70 | MP0002160_abnormal_reproductive_system | 0.98612073 |
71 | MP0009053_abnormal_anal_canal | 0.98497691 |
72 | MP0003705_abnormal_hypodermis_morpholog | 0.98443794 |
73 | MP0003115_abnormal_respiratory_system | 0.96545185 |
74 | MP0001727_abnormal_embryo_implantation | 0.96532540 |
75 | MP0003122_maternal_imprinting | 0.94995064 |
76 | MP0003221_abnormal_cardiomyocyte_apopto | 0.94804546 |
77 | MP0000733_abnormal_muscle_development | 0.94387147 |
78 | MP0003943_abnormal_hepatobiliary_system | 0.92456638 |
79 | MP0001348_abnormal_lacrimal_gland | 0.91274157 |
80 | MP0008770_decreased_survivor_rate | 0.89373183 |
81 | MP0002796_impaired_skin_barrier | 0.89355148 |
82 | MP0002925_abnormal_cardiovascular_devel | 0.88583759 |
83 | MP0002398_abnormal_bone_marrow | 0.88415393 |
84 | MP0005501_abnormal_skin_physiology | 0.86833709 |
85 | MP0005451_abnormal_body_composition | 0.86371782 |
86 | MP0009697_abnormal_copulation | 0.85220285 |
87 | MP0004264_abnormal_extraembryonic_tissu | 0.85141112 |
88 | MP0003656_abnormal_erythrocyte_physiolo | 0.84882961 |
89 | MP0001853_heart_inflammation | 0.83820887 |
90 | MP0006036_abnormal_mitochondrial_physio | 0.81213243 |
91 | MP0002166_altered_tumor_susceptibility | 0.81028272 |
92 | MP0000358_abnormal_cell_content/ | 0.79710633 |
93 | MP0008995_early_reproductive_senescence | 0.79457884 |
94 | MP0003303_peritoneal_inflammation | 0.79041049 |
95 | MP0002722_abnormal_immune_system | 0.77366801 |
96 | MP0003385_abnormal_body_wall | 0.75822653 |
97 | MP0001915_intracranial_hemorrhage | 0.75550220 |
98 | MP0010630_abnormal_cardiac_muscle | 0.74325488 |
99 | MP0004185_abnormal_adipocyte_glucose | 0.74183653 |
100 | MP0002111_abnormal_tail_morphology | 0.73235647 |
101 | MP0001784_abnormal_fluid_regulation | 0.73157769 |
102 | MP0003935_abnormal_craniofacial_develop | 0.72063312 |
103 | MP0000428_abnormal_craniofacial_morphol | 0.72044116 |
104 | MP0005384_cellular_phenotype | 0.71300720 |
105 | MP0002006_tumorigenesis | 0.69803620 |
106 | MP0003937_abnormal_limbs/digits/tail_de | 0.69532436 |
107 | MP0004381_abnormal_hair_follicle | 0.69441357 |
108 | MP0000003_abnormal_adipose_tissue | 0.68869101 |
109 | MP0000432_abnormal_head_morphology | 0.68758491 |
110 | MP0002089_abnormal_postnatal_growth/wei | 0.68571593 |
111 | MP0002429_abnormal_blood_cell | 0.68490955 |
112 | MP0000266_abnormal_heart_morphology | 0.67898212 |
113 | MP0005257_abnormal_intraocular_pressure | 0.66528648 |
114 | MP0005621_abnormal_cell_physiology | 0.65954194 |
115 | MP0003315_abnormal_perineum_morphology | 0.65701562 |
116 | MP0003699_abnormal_female_reproductive | 0.65292585 |
117 | MP0002092_abnormal_eye_morphology | 0.65082587 |
118 | MP0000689_abnormal_spleen_morphology | 0.65078568 |
119 | MP0002970_abnormal_white_adipose | 0.64665807 |
120 | MP0000678_abnormal_parathyroid_gland | 0.63668680 |
121 | MP0002697_abnormal_eye_size | 0.63063510 |
122 | MP0002114_abnormal_axial_skeleton | 0.62968723 |
123 | MP0002282_abnormal_trachea_morphology | 0.62554471 |
124 | MP0001286_abnormal_eye_development | 0.62133380 |
125 | MP0003763_abnormal_thymus_physiology | 0.60830518 |
126 | MP0003566_abnormal_cell_adhesion | 0.60211499 |
127 | MP0008961_abnormal_basal_metabolism | 0.60130371 |
128 | MP0005670_abnormal_white_adipose | 0.58833181 |
129 | MP0005666_abnormal_adipose_tissue | 0.56934844 |
130 | MP0005075_abnormal_melanosome_morpholog | 0.56837804 |
131 | MP0001881_abnormal_mammary_gland | 0.55549260 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.90403911 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.60072710 |
3 | Absent/shortened dynein arms (HP:0200106) | 4.60072710 |
4 | Ependymoma (HP:0002888) | 3.88219962 |
5 | Progressive muscle weakness (HP:0003323) | 3.67641455 |
6 | Nasal polyposis (HP:0100582) | 3.40394567 |
7 | Microvesicular hepatic steatosis (HP:0001414) | 3.26432580 |
8 | Selective tooth agenesis (HP:0001592) | 3.23751214 |
9 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.21976430 |
10 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.21976430 |
11 | Medulloblastoma (HP:0002885) | 3.10755682 |
12 | Septate vagina (HP:0001153) | 3.08058463 |
13 | Abnormality of the lower motor neuron (HP:0002366) | 3.04992199 |
14 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.01948403 |
15 | Progressive external ophthalmoplegia (HP:0000590) | 2.99065018 |
16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.90626741 |
17 | Rhinitis (HP:0012384) | 2.89248101 |
18 | Abnormality of the astrocytes (HP:0100707) | 2.86690027 |
19 | Astrocytoma (HP:0009592) | 2.86690027 |
20 | Multiple enchondromatosis (HP:0005701) | 2.86386883 |
21 | Reticulocytopenia (HP:0001896) | 2.85474884 |
22 | Abnormality of glycolysis (HP:0004366) | 2.84820145 |
23 | Urethral obstruction (HP:0000796) | 2.84529772 |
24 | Supernumerary spleens (HP:0009799) | 2.76390668 |
25 | Increased nuchal translucency (HP:0010880) | 2.73390239 |
26 | Impulsivity (HP:0100710) | 2.70138282 |
27 | Infertility (HP:0000789) | 2.67943985 |
28 | Abnormality of the nasal mucosa (HP:0000433) | 2.66302164 |
29 | Basal cell carcinoma (HP:0002671) | 2.59292658 |
30 | Rib fusion (HP:0000902) | 2.57890152 |
31 | Amyotrophic lateral sclerosis (HP:0007354) | 2.53697529 |
32 | Abnormal number of erythroid precursors (HP:0012131) | 2.50933230 |
33 | Abnormal gallbladder physiology (HP:0012438) | 2.49083786 |
34 | Cholecystitis (HP:0001082) | 2.49083786 |
35 | Male infertility (HP:0003251) | 2.43882170 |
36 | Abnormality of the labia minora (HP:0012880) | 2.43185404 |
37 | Neoplasm of striated muscle (HP:0009728) | 2.41952106 |
38 | Volvulus (HP:0002580) | 2.40563883 |
39 | Rhabdomyosarcoma (HP:0002859) | 2.39472850 |
40 | Chronic bronchitis (HP:0004469) | 2.39409542 |
41 | Proximal placement of thumb (HP:0009623) | 2.39142819 |
42 | Trismus (HP:0000211) | 2.36636052 |
43 | Ectopic kidney (HP:0000086) | 2.35409409 |
44 | Degeneration of anterior horn cells (HP:0002398) | 2.32690360 |
45 | Abnormality of the anterior horn cell (HP:0006802) | 2.32690360 |
46 | Increased serum pyruvate (HP:0003542) | 2.31083372 |
47 | Neoplasm of the oral cavity (HP:0100649) | 2.28594780 |
48 | Heterotopia (HP:0002282) | 2.27974837 |
49 | Secondary amenorrhea (HP:0000869) | 2.27665169 |
50 | Cortical dysplasia (HP:0002539) | 2.26649543 |
51 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.26276045 |
52 | Patellar aplasia (HP:0006443) | 2.25483050 |
53 | Deviation of the thumb (HP:0009603) | 2.24126953 |
54 | Abnormal ciliary motility (HP:0012262) | 2.23837989 |
55 | Abnormality of chromosome segregation (HP:0002916) | 2.23355565 |
56 | Short humerus (HP:0005792) | 2.22995004 |
57 | Premature ovarian failure (HP:0008209) | 2.21981194 |
58 | High pitched voice (HP:0001620) | 2.21724821 |
59 | Missing ribs (HP:0000921) | 2.21608807 |
60 | Hyperacusis (HP:0010780) | 2.20788378 |
61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.20301612 |
62 | Supernumerary ribs (HP:0005815) | 2.19486900 |
63 | Unilateral renal agenesis (HP:0000122) | 2.18777789 |
64 | Absent radius (HP:0003974) | 2.18685851 |
65 | Short 4th metacarpal (HP:0010044) | 2.18108355 |
66 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.18108355 |
67 | Absent thumb (HP:0009777) | 2.17913095 |
68 | Macrocytic anemia (HP:0001972) | 2.17347091 |
69 | Renal duplication (HP:0000075) | 2.15491514 |
70 | Agnosia (HP:0010524) | 2.14730606 |
71 | Squamous cell carcinoma (HP:0002860) | 2.12176715 |
72 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.12090778 |
73 | Glioma (HP:0009733) | 2.11477708 |
74 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.09744101 |
75 | Chromsome breakage (HP:0040012) | 2.09627824 |
76 | Facial cleft (HP:0002006) | 2.09451425 |
77 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.08669145 |
78 | Facial hemangioma (HP:0000329) | 2.08516522 |
79 | Deep philtrum (HP:0002002) | 2.07894411 |
80 | Abnormality of the ileum (HP:0001549) | 2.06907960 |
81 | Meckel diverticulum (HP:0002245) | 2.05734062 |
82 | Absent forearm bone (HP:0003953) | 2.04611205 |
83 | Aplasia involving forearm bones (HP:0009822) | 2.04611205 |
84 | Ragged-red muscle fibers (HP:0003200) | 2.04585360 |
85 | Cafe-au-lait spot (HP:0000957) | 2.03538490 |
86 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.03402573 |
87 | Upper limb muscle weakness (HP:0003484) | 2.03128203 |
88 | Glossoptosis (HP:0000162) | 2.02542360 |
89 | Obsessive-compulsive behavior (HP:0000722) | 2.01619325 |
90 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.01554735 |
91 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.01384185 |
92 | Abnormality of chromosome stability (HP:0003220) | 1.98640224 |
93 | Carpal bone hypoplasia (HP:0001498) | 1.97208509 |
94 | Abdominal situs inversus (HP:0003363) | 1.97033462 |
95 | Abnormality of abdominal situs (HP:0011620) | 1.97033462 |
96 | High anterior hairline (HP:0009890) | 1.93651464 |
97 | Small intestinal stenosis (HP:0012848) | 1.93645073 |
98 | Duodenal stenosis (HP:0100867) | 1.93645073 |
99 | Overlapping toe (HP:0001845) | 1.91923219 |
100 | Prominent nose (HP:0000448) | 1.91652000 |
101 | Embryonal renal neoplasm (HP:0011794) | 1.90748671 |
102 | Breast hypoplasia (HP:0003187) | 1.90246816 |
103 | Choanal atresia (HP:0000453) | 1.89981482 |
104 | Abnormality of cochlea (HP:0000375) | 1.89499986 |
105 | Long palpebral fissure (HP:0000637) | 1.89022361 |
106 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.88907693 |
107 | Bronchitis (HP:0012387) | 1.88796260 |
108 | Colon cancer (HP:0003003) | 1.87668140 |
109 | Atresia of the external auditory canal (HP:0000413) | 1.87497946 |
110 | Bronchiectasis (HP:0002110) | 1.87462400 |
111 | Trigonocephaly (HP:0000243) | 1.87225486 |
112 | Dysmetric saccades (HP:0000641) | 1.87107048 |
113 | Pseudobulbar signs (HP:0002200) | 1.87081079 |
114 | Abnormality of the salivary glands (HP:0010286) | 1.86558529 |
115 | Horseshoe kidney (HP:0000085) | 1.86070844 |
116 | Esophageal atresia (HP:0002032) | 1.84290398 |
117 | Abnormal number of incisors (HP:0011064) | 1.84253702 |
118 | Deep palmar crease (HP:0006191) | 1.84191511 |
119 | Broad distal phalanx of finger (HP:0009836) | 1.83839033 |
120 | Asplenia (HP:0001746) | 1.83183851 |
121 | Short middle phalanx of the 5th finger (HP:0004220) | 1.83056253 |
122 | Dysphonia (HP:0001618) | 1.82510573 |
123 | Abnormal lung lobation (HP:0002101) | 1.82488302 |
124 | Broad palm (HP:0001169) | 1.81264914 |
125 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.81110837 |
126 | Insomnia (HP:0100785) | 1.80790208 |
127 | Abnormality of the carotid arteries (HP:0005344) | 1.80756053 |
128 | Insidious onset (HP:0003587) | 1.80440028 |
129 | Termporal pattern (HP:0011008) | 1.80440028 |
130 | Acute myeloid leukemia (HP:0004808) | 1.79719685 |
131 | Neuroblastic tumors (HP:0004376) | 1.79434208 |
132 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.79434208 |
133 | Neuroblastoma (HP:0003006) | 1.79434208 |
134 | Primitive neuroectodermal tumor (HP:0030065) | 1.79434208 |
135 | Abnormality of the preputium (HP:0100587) | 1.78809479 |
136 | Abnormality of the fingertips (HP:0001211) | 1.77642214 |
137 | Embryonal neoplasm (HP:0002898) | 1.77631879 |
138 | Hypergonadotropic hypogonadism (HP:0000815) | 1.76187405 |
139 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.75851989 |
140 | Gout (HP:0001997) | 1.75576743 |
141 | Myelodysplasia (HP:0002863) | 1.74416161 |
142 | Abnormality of reticulocytes (HP:0004312) | 1.74077535 |
143 | Truncus arteriosus (HP:0001660) | 1.73217281 |
144 | Pelvic girdle muscle weakness (HP:0003749) | 1.72630536 |
145 | Acute lymphatic leukemia (HP:0006721) | 1.71719275 |
146 | Cleft eyelid (HP:0000625) | 1.71643524 |
147 | Birth length less than 3rd percentile (HP:0003561) | 1.71143792 |
148 | Short ribs (HP:0000773) | 1.70584621 |
149 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.69805974 |
150 | Skin tags (HP:0010609) | 1.69628210 |
151 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.69233967 |
152 | Single umbilical artery (HP:0001195) | 1.69233967 |
153 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.69233967 |
154 | Neoplasm of the adrenal cortex (HP:0100641) | 1.68719935 |
155 | Overriding aorta (HP:0002623) | 1.68638130 |
156 | Long eyelashes (HP:0000527) | 1.68563749 |
157 | Shoulder girdle muscle weakness (HP:0003547) | 1.68473405 |
158 | Neoplasm of the pancreas (HP:0002894) | 1.68353594 |
159 | Annular pancreas (HP:0001734) | 1.68243415 |
160 | Personality changes (HP:0000751) | 1.67604225 |
161 | Pallor (HP:0000980) | 1.67418472 |
162 | Elfin facies (HP:0004428) | 1.64210289 |
163 | Impaired proprioception (HP:0010831) | 1.64150118 |
164 | Orthostatic hypotension (HP:0001278) | 1.61270331 |
165 | Preauricular skin tag (HP:0000384) | 1.58537850 |
166 | Progressive hearing impairment (HP:0001730) | 1.58277990 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 4.22535378 |
2 | CDC7 | 3.92190878 |
3 | SMG1 | 3.68513429 |
4 | ICK | 3.50111233 |
5 | NEK2 | 3.32652492 |
6 | EEF2K | 3.30092661 |
7 | MAP3K10 | 3.02668821 |
8 | BUB1 | 2.87848743 |
9 | VRK2 | 2.75423623 |
10 | TTK | 2.41669129 |
11 | PNCK | 2.40895101 |
12 | WEE1 | 2.36510807 |
13 | PDK4 | 2.34563257 |
14 | PDK3 | 2.34563257 |
15 | TESK1 | 2.20941678 |
16 | TAF1 | 2.11197851 |
17 | PRKD3 | 2.07928443 |
18 | NME2 | 2.05145510 |
19 | PRPF4B | 2.04606006 |
20 | STK10 | 1.76615524 |
21 | ALK | 1.68285829 |
22 | MAP3K9 | 1.63738224 |
23 | PASK | 1.59002949 |
24 | MAP3K8 | 1.55388024 |
25 | TESK2 | 1.54704426 |
26 | CDK4 | 1.52373310 |
27 | CDK7 | 1.51444244 |
28 | NEK1 | 1.49377960 |
29 | KSR2 | 1.46882913 |
30 | SIK3 | 1.46227143 |
31 | TYRO3 | 1.42904090 |
32 | RPS6KB2 | 1.42277384 |
33 | CHEK1 | 1.41663127 |
34 | TSSK6 | 1.38175365 |
35 | PLK1 | 1.36728891 |
36 | PKN2 | 1.36636570 |
37 | TRIB3 | 1.34385277 |
38 | ATR | 1.30232288 |
39 | BRD4 | 1.28189637 |
40 | CHEK2 | 1.26400246 |
41 | MAP4K1 | 1.21142466 |
42 | EIF2AK3 | 1.20891341 |
43 | GRK6 | 1.17649261 |
44 | MTOR | 1.17592027 |
45 | PBK | 1.13419155 |
46 | LATS2 | 1.09551017 |
47 | PAK4 | 1.07993605 |
48 | MAP3K14 | 1.00986754 |
49 | CDK8 | 0.97048189 |
50 | BMX | 0.96733879 |
51 | PDK2 | 0.96509751 |
52 | EIF2AK2 | 0.96267469 |
53 | AURKA | 0.95535958 |
54 | VRK1 | 0.94916543 |
55 | NME1 | 0.94504112 |
56 | MET | 0.94161707 |
57 | CDK2 | 0.94140441 |
58 | STK3 | 0.94039602 |
59 | ATM | 0.93710167 |
60 | MST1R | 0.91062280 |
61 | AURKB | 0.89024403 |
62 | MST4 | 0.85407430 |
63 | PAK1 | 0.84778127 |
64 | DYRK3 | 0.84139016 |
65 | PTK2B | 0.83663283 |
66 | DAPK1 | 0.80588278 |
67 | EPHA2 | 0.80487855 |
68 | SIK1 | 0.79916658 |
69 | CDK6 | 0.78130065 |
70 | TRIM28 | 0.77547506 |
71 | CDK19 | 0.76802186 |
72 | IRAK3 | 0.76497362 |
73 | MKNK1 | 0.75744203 |
74 | CLK1 | 0.75658054 |
75 | FGFR4 | 0.75533490 |
76 | PLK3 | 0.75173210 |
77 | MAP3K13 | 0.74713738 |
78 | TAOK1 | 0.72225950 |
79 | PIM1 | 0.66715158 |
80 | CDK1 | 0.66084653 |
81 | MAP2K2 | 0.65589761 |
82 | SRPK1 | 0.64514546 |
83 | MELK | 0.63759070 |
84 | STK16 | 0.63523436 |
85 | BRSK1 | 0.63202744 |
86 | PAK2 | 0.61274915 |
87 | STK4 | 0.59659248 |
88 | ACVR1B | 0.59365242 |
89 | IRAK2 | 0.59289840 |
90 | SIK2 | 0.58753634 |
91 | BRAF | 0.57437806 |
92 | CAMK1D | 0.55856962 |
93 | CSNK1E | 0.55433555 |
94 | UHMK1 | 0.54923916 |
95 | MKNK2 | 0.53172557 |
96 | ARAF | 0.52513811 |
97 | DMPK | 0.52465432 |
98 | BRSK2 | 0.51558314 |
99 | SCYL2 | 0.51337833 |
100 | MAP3K11 | 0.50861333 |
101 | TGFBR1 | 0.49014207 |
102 | PTK6 | 0.48558987 |
103 | CDK11A | 0.47963221 |
104 | CDK9 | 0.47614398 |
105 | WNK1 | 0.47561920 |
106 | MAP3K2 | 0.47417030 |
107 | PAK6 | 0.47401796 |
108 | EIF2AK1 | 0.46876909 |
109 | LRRK2 | 0.45520161 |
110 | RPS6KA1 | 0.44909503 |
111 | CSNK1D | 0.44899349 |
112 | FGR | 0.44700152 |
113 | CDK14 | 0.44299711 |
114 | CDK15 | 0.44156050 |
115 | CSNK2A2 | 0.43056624 |
116 | CDK3 | 0.39270600 |
117 | PRKDC | 0.38716579 |
118 | MAPK14 | 0.38315028 |
119 | CDK18 | 0.37975290 |
120 | RPS6KA4 | 0.37826630 |
121 | GSK3B | 0.36943984 |
122 | MAPK11 | 0.34792362 |
123 | PLK4 | 0.33502065 |
124 | CSNK1G1 | 0.33331526 |
125 | DYRK1B | 0.33046477 |
126 | TAOK2 | 0.33020426 |
127 | AKT2 | 0.32921996 |
128 | MAPK10 | 0.32305414 |
129 | STK38 | 0.32073228 |
130 | MAPK1 | 0.30773403 |
131 | CAMK1G | 0.29422125 |
132 | RAF1 | 0.29186975 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.93038313 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.46229084 |
3 | RNA transport_Homo sapiens_hsa03013 | 3.36954983 |
4 | * Spliceosome_Homo sapiens_hsa03040 | 3.20769156 |
5 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.78766563 |
6 | Cell cycle_Homo sapiens_hsa04110 | 2.75733391 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.65908499 |
8 | Base excision repair_Homo sapiens_hsa03410 | 2.60010972 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.18586511 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.07420683 |
11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.06181525 |
12 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.97786904 |
13 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.92707346 |
14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.75132105 |
15 | RNA degradation_Homo sapiens_hsa03018 | 1.67967681 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.60066627 |
17 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.56540054 |
18 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.46721841 |
19 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.45300313 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.32422687 |
21 | RNA polymerase_Homo sapiens_hsa03020 | 1.31282707 |
22 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.31215692 |
23 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.30376782 |
24 | Ribosome_Homo sapiens_hsa03010 | 1.29649000 |
25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.20346532 |
26 | Thyroid cancer_Homo sapiens_hsa05216 | 1.19926816 |
27 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.14381654 |
28 | Carbon metabolism_Homo sapiens_hsa01200 | 1.14072514 |
29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.11841991 |
30 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.09996688 |
31 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.09942202 |
32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.09581760 |
33 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.08623972 |
34 | HTLV-I infection_Homo sapiens_hsa05166 | 1.08123713 |
35 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.06313574 |
36 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.04512004 |
37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.04176465 |
38 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.03250287 |
39 | Colorectal cancer_Homo sapiens_hsa05210 | 1.02188406 |
40 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.00388041 |
41 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.99487824 |
42 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.98967123 |
43 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.98196831 |
44 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.97181263 |
45 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.95349268 |
46 | Proteasome_Homo sapiens_hsa03050 | 0.94687217 |
47 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.93910025 |
48 | Bladder cancer_Homo sapiens_hsa05219 | 0.92014953 |
49 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.92000929 |
50 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.90208045 |
51 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.89189895 |
52 | Shigellosis_Homo sapiens_hsa05131 | 0.86687421 |
53 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.85727313 |
54 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.85041652 |
55 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.84448609 |
56 | Adherens junction_Homo sapiens_hsa04520 | 0.80857745 |
57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.80232567 |
58 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.79619830 |
59 | Protein export_Homo sapiens_hsa03060 | 0.75995635 |
60 | Circadian rhythm_Homo sapiens_hsa04710 | 0.74397974 |
61 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.73168066 |
62 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.72668158 |
63 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.72518373 |
64 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.72260776 |
65 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.72166418 |
66 | Long-term potentiation_Homo sapiens_hsa04720 | 0.71152909 |
67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.70181995 |
68 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.68319088 |
69 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.66770526 |
70 | Endometrial cancer_Homo sapiens_hsa05213 | 0.66700041 |
71 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66468603 |
72 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.64888832 |
73 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.63971688 |
74 | Glioma_Homo sapiens_hsa05214 | 0.63647083 |
75 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.63529389 |
76 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.63114711 |
77 | Prostate cancer_Homo sapiens_hsa05215 | 0.62499507 |
78 | Tight junction_Homo sapiens_hsa04530 | 0.62365927 |
79 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.62000773 |
80 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60999876 |
81 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.60757590 |
82 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.58130468 |
83 | Pathways in cancer_Homo sapiens_hsa05200 | 0.56741196 |
84 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56537764 |
85 | Measles_Homo sapiens_hsa05162 | 0.55325678 |
86 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.55180449 |
87 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.54558594 |
88 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.54375768 |
89 | Purine metabolism_Homo sapiens_hsa00230 | 0.51947822 |
90 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.51725569 |
91 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51632177 |
92 | Endocytosis_Homo sapiens_hsa04144 | 0.51273659 |
93 | Sulfur relay system_Homo sapiens_hsa04122 | 0.51059418 |
94 | Lysine degradation_Homo sapiens_hsa00310 | 0.50910543 |
95 | Hepatitis B_Homo sapiens_hsa05161 | 0.50590188 |
96 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48744525 |
97 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.47395307 |
98 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.46974359 |
99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43409898 |
100 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.43183455 |
101 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.43001009 |
102 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42370653 |
103 | Legionellosis_Homo sapiens_hsa05134 | 0.41704757 |
104 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.41669334 |
105 | Apoptosis_Homo sapiens_hsa04210 | 0.40664477 |
106 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.40599120 |
107 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.39184264 |
108 | Salmonella infection_Homo sapiens_hsa05132 | 0.38535586 |
109 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.36965123 |
110 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.36804269 |
111 | Gap junction_Homo sapiens_hsa04540 | 0.36721005 |
112 | Huntingtons disease_Homo sapiens_hsa05016 | 0.35281499 |
113 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.34541488 |
114 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.32495063 |
115 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.31865888 |
116 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.31727444 |
117 | Influenza A_Homo sapiens_hsa05164 | 0.31045979 |
118 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.30736715 |
119 | Melanogenesis_Homo sapiens_hsa04916 | 0.30386282 |
120 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.27096354 |
121 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.23028221 |
122 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.23015969 |
123 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.21939973 |
124 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.20436181 |
125 | Prion diseases_Homo sapiens_hsa05020 | 0.19618818 |