WDHD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)5.18513755
2DNA unwinding involved in DNA replication (GO:0006268)5.14427551
3maturation of 5.8S rRNA (GO:0000460)5.08904021
4telomere maintenance via semi-conservative replication (GO:0032201)5.02226563
5establishment of integrated proviral latency (GO:0075713)5.01623919
6DNA replication initiation (GO:0006270)4.99579980
7nuclear pore organization (GO:0006999)4.96489950
8DNA strand elongation (GO:0022616)4.94511578
9protein localization to kinetochore (GO:0034501)4.73141719
10DNA replication-dependent nucleosome organization (GO:0034723)4.60723985
11DNA replication-dependent nucleosome assembly (GO:0006335)4.60723985
12nuclear pore complex assembly (GO:0051292)4.58946080
13kinetochore organization (GO:0051383)4.55470713
14telomere maintenance via recombination (GO:0000722)4.55202851
15ribosomal large subunit biogenesis (GO:0042273)4.54970584
16DNA replication checkpoint (GO:0000076)4.51931394
17mitotic recombination (GO:0006312)4.50123375
18negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.30660562
19alternative mRNA splicing, via spliceosome (GO:0000380)4.22537875
20chaperone-mediated protein transport (GO:0072321)4.16475914
21chromatin remodeling at centromere (GO:0031055)4.13519623
22kinetochore assembly (GO:0051382)4.13388922
23CENP-A containing nucleosome assembly (GO:0034080)4.09694122
24telomere maintenance via telomere lengthening (GO:0010833)3.99412078
25protein localization to chromosome, centromeric region (GO:0071459)3.99374275
26DNA replication-independent nucleosome organization (GO:0034724)3.97276072
27DNA replication-independent nucleosome assembly (GO:0006336)3.97276072
28non-recombinational repair (GO:0000726)3.96456854
29double-strand break repair via nonhomologous end joining (GO:0006303)3.96456854
30ribosomal small subunit assembly (GO:0000028)3.92936789
31regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.89913049
32negative regulation of RNA splicing (GO:0033119)3.89373020
33nucleotide-excision repair, DNA gap filling (GO:0006297)3.87090262
34negative regulation of mRNA processing (GO:0050686)3.85610630
35establishment of viral latency (GO:0019043)3.77089026
36meiotic chromosome segregation (GO:0045132)3.75965721
37attachment of spindle microtubules to kinetochore (GO:0008608)3.68946816
38mitotic metaphase plate congression (GO:0007080)3.68702921
39protein K6-linked ubiquitination (GO:0085020)3.65611235
40mitotic nuclear envelope disassembly (GO:0007077)3.65609176
41histone exchange (GO:0043486)3.62022096
42regulation of chromosome segregation (GO:0051983)3.60175007
43regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.59496611
44pore complex assembly (GO:0046931)3.58953430
45ribosome assembly (GO:0042255)3.58364144
46regulation of DNA endoreduplication (GO:0032875)3.58167800
47mitotic sister chromatid segregation (GO:0000070)3.56521627
48mitotic spindle checkpoint (GO:0071174)3.53892262
49regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.49825174
50IMP metabolic process (GO:0046040)3.49645516
51nucleobase biosynthetic process (GO:0046112)3.46705624
52DNA double-strand break processing (GO:0000729)3.46458536
53mitotic chromosome condensation (GO:0007076)3.46168200
54sister chromatid segregation (GO:0000819)3.43847044
55translesion synthesis (GO:0019985)3.43009718
56metaphase plate congression (GO:0051310)3.42780968
57regulation of helicase activity (GO:0051095)3.42246802
58regulation of centrosome cycle (GO:0046605)3.41673894
59regulation of nuclear cell cycle DNA replication (GO:0033262)3.41302351
60maturation of SSU-rRNA (GO:0030490)3.40818604
61IMP biosynthetic process (GO:0006188)3.40266310
62mitotic G2/M transition checkpoint (GO:0044818)3.39820190
63membrane disassembly (GO:0030397)3.38324998
64nuclear envelope disassembly (GO:0051081)3.38324998
65regulation of double-strand break repair via homologous recombination (GO:0010569)3.37535962
66replication fork processing (GO:0031297)3.37462611
67regulation of mitotic sister chromatid separation (GO:0010965)3.36868396
68regulation of mitotic sister chromatid segregation (GO:0033047)3.36868396
69regulation of sister chromatid segregation (GO:0033045)3.36868396
70positive regulation of chromosome segregation (GO:0051984)3.35419075
71DNA duplex unwinding (GO:0032508)3.31931446
72regulation of histone H3-K9 methylation (GO:0051570)3.31609127
73DNA geometric change (GO:0032392)3.31371007
74regulation of sister chromatid cohesion (GO:0007063)3.30602511
75DNA strand renaturation (GO:0000733)3.27615636
76L-serine metabolic process (GO:0006563)3.25151096
77negative regulation of mRNA metabolic process (GO:1903312)3.24626731
78chromatin assembly or disassembly (GO:0006333)3.24349774
79pre-miRNA processing (GO:0031054)3.22411011
80regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.21895627
81ATP-dependent chromatin remodeling (GO:0043044)3.19584001
82telomere maintenance (GO:0000723)3.19533626
83chromosome condensation (GO:0030261)3.18908250
84DNA topological change (GO:0006265)3.18132062
85termination of RNA polymerase II transcription (GO:0006369)3.18079927
86DNA ligation (GO:0006266)3.17621466
87viral transcription (GO:0019083)3.17506962
88telomere organization (GO:0032200)3.17390723
89formation of translation preinitiation complex (GO:0001731)3.16727183
90translational termination (GO:0006415)3.12707015
91negative regulation of DNA recombination (GO:0045910)3.12185855
92DNA catabolic process, exonucleolytic (GO:0000738)3.11234626
93regulation of centrosome duplication (GO:0010824)3.10890600
94spindle checkpoint (GO:0031577)3.10549835
95spindle assembly checkpoint (GO:0071173)3.10063741
96mitotic sister chromatid cohesion (GO:0007064)3.09832720
97regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.08981792
98regulation of mitotic spindle checkpoint (GO:1903504)3.08981792
99DNA synthesis involved in DNA repair (GO:0000731)3.07947426
100postreplication repair (GO:0006301)3.07421332
101negative regulation of DNA-dependent DNA replication (GO:2000104)3.07264478
102regulation of centriole replication (GO:0046599)3.06725168
103establishment of chromosome localization (GO:0051303)3.06178953
104somatic diversification of immune receptors via somatic mutation (GO:0002566)3.04408188
105somatic hypermutation of immunoglobulin genes (GO:0016446)3.04408188
106protein localization to chromosome (GO:0034502)3.04084464
107protein complex localization (GO:0031503)3.02958728
108ribonucleoprotein complex biogenesis (GO:0022613)3.02295466
109DNA replication (GO:0006260)3.02063553
110regulation of double-strand break repair (GO:2000779)3.01469795
111maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.00914210
112mismatch repair (GO:0006298)3.00629115
113negative regulation of chromosome segregation (GO:0051985)2.99844042
114purine nucleobase biosynthetic process (GO:0009113)2.99526068
115negative regulation of mitotic sister chromatid separation (GO:2000816)2.98432914
116negative regulation of mitotic sister chromatid segregation (GO:0033048)2.98432914
117negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.98432914
118negative regulation of sister chromatid segregation (GO:0033046)2.98432914
119positive regulation of cell cycle checkpoint (GO:1901978)2.96844131
120DNA integration (GO:0015074)2.95869879
121transcription-coupled nucleotide-excision repair (GO:0006283)2.94167040
122mitotic spindle assembly checkpoint (GO:0007094)2.93838365
123spliceosomal snRNP assembly (GO:0000387)2.93776505
124negative regulation of epidermal cell differentiation (GO:0045605)2.93533000
125chromosome segregation (GO:0007059)2.93479021
126folic acid-containing compound biosynthetic process (GO:0009396)2.92568571
127RNA splicing, via transesterification reactions (GO:0000375)2.91270698
128mRNA splicing, via spliceosome (GO:0000398)2.90840818
129RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.90840818
130DNA conformation change (GO:0071103)2.90611591
131regulation of mitotic metaphase/anaphase transition (GO:0030071)2.90408339
132negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.89850944

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.99500715
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.63611569
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.92730311
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.69659262
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.90610680
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.68861906
7* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.67620420
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.65405047
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.61467677
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.52883656
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.45302423
12EGR1_19374776_ChIP-ChIP_THP-1_Human2.39305532
13E2F1_21310950_ChIP-Seq_MCF-7_Human2.35549168
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.28431232
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.27219751
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.26168574
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.23933124
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.19602802
19MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.19044446
20* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16810144
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14913815
22XRN2_22483619_ChIP-Seq_HELA_Human2.13880362
23AR_21909140_ChIP-Seq_LNCAP_Human2.10639010
24* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.07899428
25VDR_23849224_ChIP-Seq_CD4+_Human2.01467021
26E2F7_22180533_ChIP-Seq_HELA_Human12.0480294
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97642100
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.95175928
29FOXP3_21729870_ChIP-Seq_TREG_Human1.90208944
30NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.88026157
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.87076307
32* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.76788677
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.75430184
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.75262188
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.71825145
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.68467078
37* TTF2_22483619_ChIP-Seq_HELA_Human1.68085746
38DCP1A_22483619_ChIP-Seq_HELA_Human1.64032320
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.63473297
40* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61515163
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.60651998
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.60627012
43HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.57932978
44ELK1_19687146_ChIP-ChIP_HELA_Human1.55920930
45SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.52902189
46* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.52364693
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49903774
48GABP_19822575_ChIP-Seq_HepG2_Human1.48061174
49MYC_22102868_ChIP-Seq_BL_Human1.44212680
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43761731
51TP63_19390658_ChIP-ChIP_HaCaT_Human1.42474011
52CIITA_25753668_ChIP-Seq_RAJI_Human1.41891961
53KDM5A_27292631_Chip-Seq_BREAST_Human1.41192734
54PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.39728959
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36031157
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.34227969
57TFEB_21752829_ChIP-Seq_HELA_Human1.32434936
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.30366941
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.28878444
60E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.25268502
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22719356
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22671498
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.20189127
64* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19359697
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.19317254
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16093797
67YY1_21170310_ChIP-Seq_MESCs_Mouse1.14869127
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13918504
69SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.12514823
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.12287396
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.11936597
72NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.11587661
73EWS_26573619_Chip-Seq_HEK293_Human1.10812048
74KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.09826953
75CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.08883388
76SOX17_20123909_ChIP-Seq_XEN_Mouse1.05586390
77VDR_21846776_ChIP-Seq_THP-1_Human1.03256451
78MYC_18940864_ChIP-ChIP_HL60_Human0.99079312
79SPI1_23547873_ChIP-Seq_NB4_Human0.96469632
80SALL1_21062744_ChIP-ChIP_HESCs_Human0.95831108
81SRF_21415370_ChIP-Seq_HL-1_Mouse0.95635624
82HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95275020
83NOTCH1_21737748_ChIP-Seq_TLL_Human0.94952015
84* FUS_26573619_Chip-Seq_HEK293_Human0.94820082
85TCF3_18692474_ChIP-Seq_MEFs_Mouse0.94486789
86IRF1_19129219_ChIP-ChIP_H3396_Human0.92851386
87* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92223338
88RBPJ_22232070_ChIP-Seq_NCS_Mouse0.91993481
89IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.89554556
90* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.87393030
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.85963851
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85056967
93STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84852546
94NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.84624499
95KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.83169587
96KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.83169587
97KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.83169587
98KLF4_18555785_ChIP-Seq_MESCs_Mouse0.82060350
99SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.81053040
100DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80672388
101TCF3_18692474_ChIP-Seq_MESCs_Mouse0.76347384
102* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.76265260
103SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.75341225
104SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.74730044
105ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.74516427
106NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.73681233
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.72500954
108* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.72339588
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.71315843
110CHD1_26751641_Chip-Seq_LNCaP_Human0.71094212
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.70164294
112ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.69435692
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.69257736
114DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.69018571
115ESR1_15608294_ChIP-ChIP_MCF-7_Human0.68685319
116* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.68053454
117MYB_26560356_Chip-Seq_TH1_Human0.66730220
118PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.65389815
119CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.64768388
120* NANOG_16153702_ChIP-ChIP_HESCs_Human0.63913361

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.02175705
2MP0003693_abnormal_embryo_hatching4.98697108
3MP0003111_abnormal_nucleus_morphology4.55509471
4MP0008057_abnormal_DNA_replication4.45086796
5MP0003077_abnormal_cell_cycle3.91142028
6MP0004957_abnormal_blastocyst_morpholog3.65407305
7MP0008058_abnormal_DNA_repair3.53531153
8MP0008877_abnormal_DNA_methylation2.92346328
9MP0008932_abnormal_embryonic_tissue2.74899612
10MP0003123_paternal_imprinting2.61425445
11MP0008007_abnormal_cellular_replicative2.54619224
12MP0002396_abnormal_hematopoietic_system2.45553472
13MP0009697_abnormal_copulation2.37493747
14MP0001730_embryonic_growth_arrest2.29846524
15MP0003786_premature_aging2.16191732
16MP0000350_abnormal_cell_proliferation2.07330081
17MP0003121_genomic_imprinting1.86321860
18MP0010307_abnormal_tumor_latency1.86202657
19MP0004808_abnormal_hematopoietic_stem1.76058069
20MP0003890_abnormal_embryonic-extraembry1.72551713
21MP0000490_abnormal_crypts_of1.68394806
22MP0010352_gastrointestinal_tract_polyps1.56565598
23MP0006292_abnormal_olfactory_placode1.53407171
24MP0002210_abnormal_sex_determination1.51846333
25MP0001672_abnormal_embryogenesis/_devel1.46590908
26MP0005380_embryogenesis_phenotype1.46590908
27MP0001697_abnormal_embryo_size1.44999614
28MP0000313_abnormal_cell_death1.42719537
29MP0002019_abnormal_tumor_incidence1.40045120
30MP0005076_abnormal_cell_differentiation1.39445142
31MP0002697_abnormal_eye_size1.38489561
32MP0002085_abnormal_embryonic_tissue1.35387570
33MP0004197_abnormal_fetal_growth/weight/1.35199027
34MP0003763_abnormal_thymus_physiology1.34717775
35MP0002080_prenatal_lethality1.31981881
36MP0001145_abnormal_male_reproductive1.31956664
37MP0000537_abnormal_urethra_morphology1.31404474
38MP0010030_abnormal_orbit_morphology1.30847102
39MP0003984_embryonic_growth_retardation1.27695207
40MP0005397_hematopoietic_system_phenotyp1.26106494
41MP0001545_abnormal_hematopoietic_system1.26106494
42MP0002398_abnormal_bone_marrow1.24285904
43MP0002088_abnormal_embryonic_growth/wei1.23699226
44MP0001293_anophthalmia1.21974255
45MP0000703_abnormal_thymus_morphology1.21664068
46MP0002086_abnormal_extraembryonic_tissu1.20532388
47MP0005174_abnormal_tail_pigmentation1.20231003
48MP0000569_abnormal_digit_pigmentation1.19428236
49MP0000383_abnormal_hair_follicle1.17172645
50MP0003315_abnormal_perineum_morphology1.16734647
51MP0003567_abnormal_fetal_cardiomyocyte1.15449677
52MP0003136_yellow_coat_color1.15334885
53MP0002084_abnormal_developmental_patter1.15210416
54MP0000653_abnormal_sex_gland1.13612290
55MP0003718_maternal_effect1.13108538
56MP0001929_abnormal_gametogenesis1.12988605
57MP0002233_abnormal_nose_morphology1.10872231
58MP0005409_darkened_coat_color1.09429272
59MP0002722_abnormal_immune_system1.09319230
60MP0000689_abnormal_spleen_morphology1.08615291
61MP0000428_abnormal_craniofacial_morphol1.08579733
62MP0001346_abnormal_lacrimal_gland1.03640164
63MP0006035_abnormal_mitochondrial_morpho1.03538169
64MP0002095_abnormal_skin_pigmentation1.01549019
65MP0000566_synostosis0.99068559
66MP0001529_abnormal_vocalization0.96560302
67MP0000358_abnormal_cell_content/0.95980350
68MP0001119_abnormal_female_reproductive0.95579210
69MP0005389_reproductive_system_phenotype0.94800360
70MP0000858_altered_metastatic_potential0.92225249
71MP0002429_abnormal_blood_cell0.91227492
72MP0001919_abnormal_reproductive_system0.90723041
73MP0002160_abnormal_reproductive_system0.89844112
74MP0003937_abnormal_limbs/digits/tail_de0.89420751
75MP0000465_gastrointestinal_hemorrhage0.89087908
76MP0003861_abnormal_nervous_system0.88924352
77MP0008995_early_reproductive_senescence0.88383995
78MP0009333_abnormal_splenocyte_physiolog0.88032127
79MP0002075_abnormal_coat/hair_pigmentati0.87803580
80MP0002092_abnormal_eye_morphology0.87053133
81MP0000579_abnormal_nail_morphology0.86622359
82MP0005075_abnormal_melanosome_morpholog0.85425807
83MP0000015_abnormal_ear_pigmentation0.85244921
84MP0006072_abnormal_retinal_apoptosis0.85024994
85MP0003806_abnormal_nucleotide_metabolis0.84388055
86MP0001299_abnormal_eye_distance/0.81481007
87MP0001186_pigmentation_phenotype0.80594638
88MP0003119_abnormal_digestive_system0.79972073
89MP0000716_abnormal_immune_system0.79437317
90MP0003705_abnormal_hypodermis_morpholog0.79325659
91MP0001800_abnormal_humoral_immune0.79220554
92MP0003755_abnormal_palate_morphology0.79143430
93MP0000647_abnormal_sebaceous_gland0.78021636
94MP0003787_abnormal_imprinting0.77807163
95MP0001835_abnormal_antigen_presentation0.77500817
96MP0009672_abnormal_birth_weight0.76307080
97MP0001188_hyperpigmentation0.75902525
98MP0002102_abnormal_ear_morphology0.75869441
99MP0002254_reproductive_system_inflammat0.75149072
100MP0001177_atelectasis0.74926318
101MP0008789_abnormal_olfactory_epithelium0.74009498
102MP0000432_abnormal_head_morphology0.74009238
103MP0003221_abnormal_cardiomyocyte_apopto0.73972421
104MP0003935_abnormal_craniofacial_develop0.73182627
105MP0001286_abnormal_eye_development0.72894374
106MP0002877_abnormal_melanocyte_morpholog0.72768224
107MP0002938_white_spotting0.72133644
108MP0001853_heart_inflammation0.70311758
109MP0005501_abnormal_skin_physiology0.70265085
110MP0000049_abnormal_middle_ear0.69484258
111MP0002420_abnormal_adaptive_immunity0.68570103
112MP0004185_abnormal_adipocyte_glucose0.68547991
113MP0005671_abnormal_response_to0.68237748
114MP0001873_stomach_inflammation0.67745805
115MP0006054_spinal_hemorrhage0.67559402
116MP0001819_abnormal_immune_cell0.66891099
117MP0003385_abnormal_body_wall0.66735794
118MP0002452_abnormal_antigen_presenting0.66016882
119MP0009703_decreased_birth_body0.64946244
120MP0002751_abnormal_autonomic_nervous0.64388998
121MP0002111_abnormal_tail_morphology0.64287909
122MP0005384_cellular_phenotype0.63530651
123MP0003943_abnormal_hepatobiliary_system0.63529234
124MP0002405_respiratory_system_inflammati0.63490783
125MP0005621_abnormal_cell_physiology0.63321282
126MP0004233_abnormal_muscle_weight0.62283426
127MP0003698_abnormal_male_reproductive0.61893781
128MP0004147_increased_porphyrin_level0.61694412
129MP0002009_preneoplasia0.61678597
130MP0005499_abnormal_olfactory_system0.61405318
131MP0005394_taste/olfaction_phenotype0.61405318
132MP0001915_intracranial_hemorrhage0.61352544
133MP0005391_vision/eye_phenotype0.61042414
134MP0000427_abnormal_hair_cycle0.60822659
135MP0001727_abnormal_embryo_implantation0.60678384
136MP0003941_abnormal_skin_development0.59094612
137MP0003699_abnormal_female_reproductive0.58526968
138MP0003186_abnormal_redox_activity0.58518851
139MP0000372_irregular_coat_pigmentation0.57367342
140MP0002234_abnormal_pharynx_morphology0.55305827

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.72846257
2Chromosomal breakage induced by crosslinking agents (HP:0003221)5.65402535
3Abnormality of chromosome stability (HP:0003220)4.59999908
4Birth length less than 3rd percentile (HP:0003561)4.41369053
5Reticulocytopenia (HP:0001896)4.31121595
6Ependymoma (HP:0002888)4.28897449
7Medulloblastoma (HP:0002885)4.20869346
8Meckel diverticulum (HP:0002245)3.57805371
9Patellar aplasia (HP:0006443)3.47373676
10Abnormality of the preputium (HP:0100587)3.42821449
11Abnormality of the ileum (HP:0001549)3.40825289
12Aplasia/Hypoplasia of the uvula (HP:0010293)3.40000276
13Breast hypoplasia (HP:0003187)3.35596866
14Impulsivity (HP:0100710)3.28488174
15Aplastic anemia (HP:0001915)3.27507194
16Aplasia/Hypoplasia of the patella (HP:0006498)3.21801004
17Duplicated collecting system (HP:0000081)3.19237911
18Gonadotropin excess (HP:0000837)2.98574520
19Ectopic kidney (HP:0000086)2.92087888
20Abnormality of the renal collecting system (HP:0004742)2.91536102
21Duodenal stenosis (HP:0100867)2.90355879
22Small intestinal stenosis (HP:0012848)2.90355879
23Cortical dysplasia (HP:0002539)2.83182377
24Myelodysplasia (HP:0002863)2.81872188
25Agnosia (HP:0010524)2.80483171
26Astrocytoma (HP:0009592)2.74738062
27Abnormality of the astrocytes (HP:0100707)2.74738062
2811 pairs of ribs (HP:0000878)2.74555894
29Glioma (HP:0009733)2.71156791
30Nephroblastoma (Wilms tumor) (HP:0002667)2.70108989
31Abnormality of cells of the erythroid lineage (HP:0012130)2.60179441
32Abnormal number of erythroid precursors (HP:0012131)2.57009629
33Neoplasm of striated muscle (HP:0009728)2.56381208
34Clubbing of toes (HP:0100760)2.55902629
35Selective tooth agenesis (HP:0001592)2.55419431
36Rhabdomyosarcoma (HP:0002859)2.53241903
37Embryonal renal neoplasm (HP:0011794)2.52282583
38Multiple enchondromatosis (HP:0005701)2.45865143
39Abnormality of the carotid arteries (HP:0005344)2.45345317
40Absent thumb (HP:0009777)2.43249262
41Bone marrow hypocellularity (HP:0005528)2.42336054
42Colon cancer (HP:0003003)2.36952079
43Pallor (HP:0000980)2.35630872
44Abnormal lung lobation (HP:0002101)2.35223565
45Abnormality of the duodenum (HP:0002246)2.35007696
46Abnormality of the labia minora (HP:0012880)2.29441719
47Absent radius (HP:0003974)2.28339604
48Short thumb (HP:0009778)2.27071390
49Oral leukoplakia (HP:0002745)2.26585933
50Neoplasm of the colon (HP:0100273)2.24993307
51Premature graying of hair (HP:0002216)2.23823907
52Premature ovarian failure (HP:0008209)2.21669313
53Triphalangeal thumb (HP:0001199)2.21448677
54Volvulus (HP:0002580)2.20635715
55Abnormality of chromosome segregation (HP:0002916)2.19660660
56Sloping forehead (HP:0000340)2.19107310
57Choanal atresia (HP:0000453)2.18781005
58Duplication of thumb phalanx (HP:0009942)2.17580864
59Embryonal neoplasm (HP:0002898)2.14430421
60Horseshoe kidney (HP:0000085)2.14377874
61Supernumerary spleens (HP:0009799)2.12414188
62Abnormal number of incisors (HP:0011064)2.12083949
63Absent forearm bone (HP:0003953)2.11137918
64Aplasia involving forearm bones (HP:0009822)2.11137918
65Heterotopia (HP:0002282)2.10821251
66Aplasia/Hypoplasia of the sacrum (HP:0008517)2.09294757
67Spastic diplegia (HP:0001264)2.08977231
68Long eyelashes (HP:0000527)2.08054847
69Tracheoesophageal fistula (HP:0002575)2.07086010
70Carpal bone hypoplasia (HP:0001498)2.04465128
71Secondary amenorrhea (HP:0000869)2.03578956
72Cafe-au-lait spot (HP:0000957)2.02021151
73Abnormality of DNA repair (HP:0003254)2.01965916
74Macrocytic anemia (HP:0001972)2.01034060
75Abnormality of cochlea (HP:0000375)2.00680631
76Aplasia/Hypoplasia of the sternum (HP:0006714)2.00325295
77Amaurosis fugax (HP:0100576)2.00142447
78Increased nuchal translucency (HP:0010880)2.00128203
79Basal cell carcinoma (HP:0002671)1.99815809
80Microvesicular hepatic steatosis (HP:0001414)1.99411001
81Degeneration of anterior horn cells (HP:0002398)1.97648113
82Abnormality of the anterior horn cell (HP:0006802)1.97648113
83Abnormal spermatogenesis (HP:0008669)1.97463920
84Arteriovenous malformation (HP:0100026)1.96875296
85Deviation of the thumb (HP:0009603)1.96478003
86Lymphoma (HP:0002665)1.94691797
87Acute lymphatic leukemia (HP:0006721)1.93489161
88Aplasia/Hypoplasia of the earlobes (HP:0009906)1.92792052
89Stenosis of the external auditory canal (HP:0000402)1.92446522
90High anterior hairline (HP:0009890)1.91770162
91IgM deficiency (HP:0002850)1.89928967
92Thrombocytosis (HP:0001894)1.89852019
93Facial cleft (HP:0002006)1.89681685
94Esophageal atresia (HP:0002032)1.88231377
95Neoplasm of the pancreas (HP:0002894)1.83273026
96Abnormality of glycolysis (HP:0004366)1.82995762
97Microglossia (HP:0000171)1.82919591
98Biliary tract neoplasm (HP:0100574)1.81574778
99Increased serum pyruvate (HP:0003542)1.80599006
100Gastrointestinal carcinoma (HP:0002672)1.80017863
101Malignant gastrointestinal tract tumors (HP:0006749)1.80017863
102Rough bone trabeculation (HP:0100670)1.79371476
103Asplenia (HP:0001746)1.79053867
104Septo-optic dysplasia (HP:0100842)1.78316800
105Abnormality of the fingertips (HP:0001211)1.77319705
106Missing ribs (HP:0000921)1.77315346
107Abnormality of the septum pellucidum (HP:0007375)1.77084414
108Abnormality of methionine metabolism (HP:0010901)1.75660891
109Bifid tongue (HP:0010297)1.75117092
110Ovarian neoplasm (HP:0100615)1.74506066
111Atresia of the external auditory canal (HP:0000413)1.73745774
112Prominent nose (HP:0000448)1.72845092
113Irregular epiphyses (HP:0010582)1.71903949
114Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.70630943
115Short 4th metacarpal (HP:0010044)1.70630943
116Disinhibition (HP:0000734)1.70330564
117Pancreatic islet-cell hyperplasia (HP:0004510)1.69717282
118Neoplasm of the small intestine (HP:0100833)1.68775457
119Truncal obesity (HP:0001956)1.68577431
120Breast carcinoma (HP:0003002)1.66698637
121Pancytopenia (HP:0001876)1.66626015
122Abnormality of the prostate (HP:0008775)1.66295941
123Abnormality of the heme biosynthetic pathway (HP:0010472)1.66073491
124Hypoplastic pelvis (HP:0008839)1.65109302
125Cutis marmorata (HP:0000965)1.64958901
126Abnormality of reticulocytes (HP:0004312)1.64284656
127Absent septum pellucidum (HP:0001331)1.64259201
128Aplasia/Hypoplasia of the spleen (HP:0010451)1.63623703
129Cleft eyelid (HP:0000625)1.63581825
130Gastrointestinal atresia (HP:0002589)1.62632313
131Uterine neoplasm (HP:0010784)1.62334208
132Supernumerary bones of the axial skeleton (HP:0009144)1.62317900
133Proximal placement of thumb (HP:0009623)1.62018966
134Cellular immunodeficiency (HP:0005374)1.61532681
135Intestinal atresia (HP:0011100)1.61497156
136Slender long bone (HP:0003100)1.60130857
137Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.59508446
138Prostate neoplasm (HP:0100787)1.58500344
139Single umbilical artery (HP:0001195)1.58114385
140Abnormality of the fetal cardiovascular system (HP:0010948)1.58114385
141Abnormal umbilical cord blood vessels (HP:0011403)1.58114385
142Abnormality of serum amino acid levels (HP:0003112)1.57484754
143Neoplasm of the oral cavity (HP:0100649)1.57044441
144Short middle phalanx of the 5th finger (HP:0004220)1.56422661
145Progressive external ophthalmoplegia (HP:0000590)1.54685103
146Overlapping toe (HP:0001845)1.53977133
147Capillary hemangiomas (HP:0005306)1.49503935

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK15.23889968
2CDC74.21795748
3ACVR1B4.02450347
4WEE13.87197115
5EIF2AK33.55420981
6SRPK12.59844078
7BUB12.58735333
8PBK2.50962113
9VRK22.39410538
10BRSK12.37137518
11TAF12.33913106
12MKNK12.17114067
13PLK42.15707672
14NEK22.13520889
15MKNK22.11232799
16RPS6KA42.04175788
17ATR2.00007359
18TTK1.99742380
19CDK121.99389797
20BRSK21.86651518
21ZAK1.83262730
22STK161.75821845
23TGFBR11.75094490
24MST41.75071713
25TLK11.72452404
26PLK11.70416626
27TSSK61.59644999
28VRK11.57307671
29BRD41.56733033
30CDK41.56326177
31MAP3K111.54438994
32EIF2AK21.51488758
33CDK71.49892074
34NME21.44212464
35AURKB1.44123623
36STK41.33132607
37TRIM281.32626149
38CHEK21.29225721
39PASK1.29141920
40CHEK11.25474330
41NUAK11.20819211
42PLK31.20764343
43DYRK31.19333866
44BMPR1B1.18388088
45SMG11.09582687
46RPS6KB21.07781137
47ERBB41.06220768
48NEK11.05313496
49IRAK31.03448938
50IRAK41.02803669
51AURKA1.02457339
52TNIK0.97053335
53WNK30.96636049
54PAK40.95198058
55STK100.93779792
56MAP4K10.91337910
57MAP3K80.90446709
58* ATM0.90115993
59CCNB10.83426092
60EEF2K0.81095005
61CLK10.81013733
62LATS10.79724854
63CDK20.78626126
64RPS6KA50.77782217
65PLK20.76960028
66BCR0.76702372
67PIM10.74510840
68FGFR10.72947426
69TXK0.72230294
70MELK0.72025244
71TEC0.71481340
72BTK0.71276233
73NME10.63991964
74TESK20.62142328
75SCYL20.62023877
76BRAF0.61102942
77CDK60.59927445
78STK30.59546598
79CAMK1G0.59057622
80EPHA20.58508399
81CDK10.57486334
82MAP3K100.57064566
83CSNK2A10.55445115
84FLT30.53997985
85CSNK1G10.52456999
86CDK80.49538457
87CSNK2A20.49420445
88ERBB20.48216209
89CSNK1E0.47714566
90PDK20.46873009
91RPS6KC10.45784303
92RPS6KL10.45784303
93YES10.45127291
94NEK90.43967667
95MET0.43132513
96CDK90.42812635
97RPS6KB10.42179044
98LATS20.40497130
99CDK30.40408355
100RPS6KA60.39575908
101DAPK10.38051016
102CDK190.37219963
103ALK0.36452797
104FGFR20.35374831
105CDK180.34680842
106STK38L0.32127367
107ERBB30.31725236
108CDK150.31626918
109STK240.31072557
110MAPK70.31041475
111PRKDC0.30817226
112CDK11A0.30570661
113CAMK1D0.30121078
114MAPK140.29761825
115DYRK20.29253257
116KIT0.28723155
117MST1R0.28615591
118CSNK1G30.28298959
119EPHA40.27713740
120MAP3K40.27391253
121LYN0.23988116
122AKT10.23606592
123PKN20.22884408
124PNCK0.22731478
125PAK10.22466397
126ADRBK10.22447019
127RPS6KA10.21246114
128RPS6KA20.21188048
129PRKCI0.20685846
130MAPKAPK20.20640756
131CSNK1D0.19418997
132BLK0.19396871
133CSF1R0.19235055
134AKT30.17723591
135KDR0.15327532
136ZAP700.15294666
137GSK3B0.14929719

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.44483126
2Mismatch repair_Homo sapiens_hsa034304.65032576
3Spliceosome_Homo sapiens_hsa030403.49926948
4Homologous recombination_Homo sapiens_hsa034403.32894749
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.18811573
6Base excision repair_Homo sapiens_hsa034103.11902407
7Cell cycle_Homo sapiens_hsa041103.07286752
8Ribosome_Homo sapiens_hsa030103.07171138
9Fanconi anemia pathway_Homo sapiens_hsa034602.95952484
10RNA transport_Homo sapiens_hsa030132.86706052
11Nucleotide excision repair_Homo sapiens_hsa034202.77206362
12One carbon pool by folate_Homo sapiens_hsa006702.57632132
13RNA polymerase_Homo sapiens_hsa030202.54166324
14Proteasome_Homo sapiens_hsa030502.37654713
15Non-homologous end-joining_Homo sapiens_hsa034502.20840117
16Pyrimidine metabolism_Homo sapiens_hsa002402.19326385
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.17231378
18Systemic lupus erythematosus_Homo sapiens_hsa053221.94849990
19p53 signaling pathway_Homo sapiens_hsa041151.89317803
20RNA degradation_Homo sapiens_hsa030181.87758513
21Basal transcription factors_Homo sapiens_hsa030221.73082968
22mRNA surveillance pathway_Homo sapiens_hsa030151.72465167
23Herpes simplex infection_Homo sapiens_hsa051681.41273070
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.39032164
25Biosynthesis of amino acids_Homo sapiens_hsa012301.38461592
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36567692
27Pyruvate metabolism_Homo sapiens_hsa006201.31827350
28Propanoate metabolism_Homo sapiens_hsa006401.20420328
29Purine metabolism_Homo sapiens_hsa002301.19957127
30Viral carcinogenesis_Homo sapiens_hsa052031.18244886
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.16061100
32Epstein-Barr virus infection_Homo sapiens_hsa051691.15838376
33Steroid biosynthesis_Homo sapiens_hsa001001.15684999
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.14617731
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.09094948
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.07846167
37Carbon metabolism_Homo sapiens_hsa012001.07497284
38Vitamin B6 metabolism_Homo sapiens_hsa007501.03324976
39Primary immunodeficiency_Homo sapiens_hsa053401.01791851
40Antigen processing and presentation_Homo sapiens_hsa046120.97053670
41Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90681245
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89657080
43Fatty acid elongation_Homo sapiens_hsa000620.88470157
44Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.87910461
45Oocyte meiosis_Homo sapiens_hsa041140.87700880
46HTLV-I infection_Homo sapiens_hsa051660.87227325
47Alcoholism_Homo sapiens_hsa050340.85452981
48NF-kappa B signaling pathway_Homo sapiens_hsa040640.83048480
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82332766
50Measles_Homo sapiens_hsa051620.80460000
51MicroRNAs in cancer_Homo sapiens_hsa052060.74909389
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.74745939
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.70183636
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68305394
55Hematopoietic cell lineage_Homo sapiens_hsa046400.65426190
56Small cell lung cancer_Homo sapiens_hsa052220.64516368
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.64423806
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.61601370
59Thyroid cancer_Homo sapiens_hsa052160.60743108
60Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60432409
61RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.56890088
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56321091
63Apoptosis_Homo sapiens_hsa042100.55538154
64Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.53255705
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.52926662
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52725533
67Shigellosis_Homo sapiens_hsa051310.52154156
68Notch signaling pathway_Homo sapiens_hsa043300.50667740
69NOD-like receptor signaling pathway_Homo sapiens_hsa046210.50639092
70Parkinsons disease_Homo sapiens_hsa050120.48707540
71Hepatitis B_Homo sapiens_hsa051610.48187668
72Influenza A_Homo sapiens_hsa051640.47447234
73Cyanoamino acid metabolism_Homo sapiens_hsa004600.46253054
74Legionellosis_Homo sapiens_hsa051340.44682034
75Central carbon metabolism in cancer_Homo sapiens_hsa052300.44035165
76Basal cell carcinoma_Homo sapiens_hsa052170.43751249
77Allograft rejection_Homo sapiens_hsa053300.42301997
78Fatty acid metabolism_Homo sapiens_hsa012120.40999453
79TGF-beta signaling pathway_Homo sapiens_hsa043500.40464508
80Asthma_Homo sapiens_hsa053100.39889715
81Colorectal cancer_Homo sapiens_hsa052100.38427564
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37827188
83Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36826907
84Metabolic pathways_Homo sapiens_hsa011000.36419784
85Leishmaniasis_Homo sapiens_hsa051400.36277874
86Selenocompound metabolism_Homo sapiens_hsa004500.35993848
87Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35939151
88N-Glycan biosynthesis_Homo sapiens_hsa005100.35020493
89Drug metabolism - other enzymes_Homo sapiens_hsa009830.34944189
90Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.34242773
91Pathways in cancer_Homo sapiens_hsa052000.31867334
92Graft-versus-host disease_Homo sapiens_hsa053320.31450432
93Tight junction_Homo sapiens_hsa045300.30877768
94Autoimmune thyroid disease_Homo sapiens_hsa053200.30645830
95Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30631343
96Pentose phosphate pathway_Homo sapiens_hsa000300.29697380
97Oxidative phosphorylation_Homo sapiens_hsa001900.29211647
98Chronic myeloid leukemia_Homo sapiens_hsa052200.27753409
99Prostate cancer_Homo sapiens_hsa052150.27403744
100B cell receptor signaling pathway_Homo sapiens_hsa046620.27244513
101Cysteine and methionine metabolism_Homo sapiens_hsa002700.26557958
102Renin-angiotensin system_Homo sapiens_hsa046140.25913567
103Hippo signaling pathway_Homo sapiens_hsa043900.25128761
104Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.24923665
105Viral myocarditis_Homo sapiens_hsa054160.24748740
106Jak-STAT signaling pathway_Homo sapiens_hsa046300.24555013
107Melanoma_Homo sapiens_hsa052180.22453250
108Folate biosynthesis_Homo sapiens_hsa007900.22149238
109Lysine degradation_Homo sapiens_hsa003100.21374273
110Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.21305748
111Arachidonic acid metabolism_Homo sapiens_hsa005900.19999816
112Hedgehog signaling pathway_Homo sapiens_hsa043400.19448818
113Glutathione metabolism_Homo sapiens_hsa004800.19366877
114Pancreatic cancer_Homo sapiens_hsa052120.19045635
115Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.18365689
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.17714121
117Protein export_Homo sapiens_hsa030600.17207597
118Acute myeloid leukemia_Homo sapiens_hsa052210.16842500
119T cell receptor signaling pathway_Homo sapiens_hsa046600.16310547
120Bladder cancer_Homo sapiens_hsa052190.15679444
121Adherens junction_Homo sapiens_hsa045200.15613189
122Pentose and glucuronate interconversions_Homo sapiens_hsa000400.15490096
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.14637815
124Non-small cell lung cancer_Homo sapiens_hsa052230.14422603
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.14106164
126Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.13814260
127Arginine and proline metabolism_Homo sapiens_hsa003300.13062861
128Wnt signaling pathway_Homo sapiens_hsa043100.12953234
129Huntingtons disease_Homo sapiens_hsa050160.12228645
130Type I diabetes mellitus_Homo sapiens_hsa049400.11832999
131Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.11562523
132Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.11119243
133Galactose metabolism_Homo sapiens_hsa000520.10768493
134HIF-1 signaling pathway_Homo sapiens_hsa040660.10251016
135Alzheimers disease_Homo sapiens_hsa050100.08529560
136beta-Alanine metabolism_Homo sapiens_hsa004100.08367490
137Fatty acid degradation_Homo sapiens_hsa000710.08221782
138Sulfur relay system_Homo sapiens_hsa041220.06602782
139Proteoglycans in cancer_Homo sapiens_hsa052050.05516059
140Butanoate metabolism_Homo sapiens_hsa006500.03496096

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »