WDR17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a WD repeat-containing protein. It is abundantly expressed in retina and testis, and is thought to be a candidate gene for retinal disease. Alternatively spliced transcript variants have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of rhodopsin mediated signaling pathway (GO:0022400)7.19425967
2rhodopsin mediated signaling pathway (GO:0016056)6.97688368
3retinal cone cell development (GO:0046549)6.09081040
4photoreceptor cell maintenance (GO:0045494)5.24638583
5photoreceptor cell development (GO:0042461)5.06902624
6eye photoreceptor cell development (GO:0042462)4.93251757
7detection of light stimulus involved in sensory perception (GO:0050962)4.79742960
8detection of light stimulus involved in visual perception (GO:0050908)4.79742960
9protein localization to synapse (GO:0035418)4.65873427
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.63820980
11gamma-aminobutyric acid transport (GO:0015812)4.60833111
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.56558864
13behavioral response to nicotine (GO:0035095)4.48493607
14pyrimidine nucleobase catabolic process (GO:0006208)4.44204890
15regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.29911492
16retinal rod cell development (GO:0046548)4.26390446
17auditory behavior (GO:0031223)4.05723760
18positive regulation of synaptic transmission, GABAergic (GO:0032230)3.97866053
19phototransduction (GO:0007602)3.95446937
20vocalization behavior (GO:0071625)3.87984017
21detection of light stimulus (GO:0009583)3.86402963
22positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.86010955
23neuron cell-cell adhesion (GO:0007158)3.84213753
24regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.81579399
25protein-chromophore linkage (GO:0018298)3.80228337
26detection of visible light (GO:0009584)3.79637436
27dendritic spine morphogenesis (GO:0060997)3.79070423
28nucleobase catabolic process (GO:0046113)3.76599390
29phototransduction, visible light (GO:0007603)3.74962274
30cilium or flagellum-dependent cell motility (GO:0001539)3.74617798
31positive regulation of guanylate cyclase activity (GO:0031284)3.71257922
32visual perception (GO:0007601)3.67479649
33epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.67200239
34synaptic vesicle docking involved in exocytosis (GO:0016081)3.66538752
35regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.65325786
36sensory perception of light stimulus (GO:0050953)3.65049075
37ionotropic glutamate receptor signaling pathway (GO:0035235)3.62230349
38neuron-neuron synaptic transmission (GO:0007270)3.59611364
39synaptic vesicle exocytosis (GO:0016079)3.59486487
40eye photoreceptor cell differentiation (GO:0001754)3.58190938
41photoreceptor cell differentiation (GO:0046530)3.58190938
42startle response (GO:0001964)3.57224273
43regulation of glutamate receptor signaling pathway (GO:1900449)3.55085197
44mechanosensory behavior (GO:0007638)3.53438942
45negative regulation of synaptic transmission, GABAergic (GO:0032229)3.53165467
46epithelial cilium movement (GO:0003351)3.53041079
47protein localization to cilium (GO:0061512)3.52835838
48glutamate receptor signaling pathway (GO:0007215)3.47127464
49long-term memory (GO:0007616)3.46246220
50synaptic transmission, glutamatergic (GO:0035249)3.45168748
51positive regulation of neurotransmitter transport (GO:0051590)3.44002383
52presynaptic membrane assembly (GO:0097105)3.43762191
53nonmotile primary cilium assembly (GO:0035058)3.40976414
54negative regulation of cytosolic calcium ion concentration (GO:0051481)3.39807571
55response to histamine (GO:0034776)3.39404145
56primary amino compound metabolic process (GO:1901160)3.37886257
57positive regulation of action potential (GO:0045760)3.34865340
58neuronal action potential (GO:0019228)3.34707420
59regulation of guanylate cyclase activity (GO:0031282)3.33528808
60regulation of synaptic vesicle exocytosis (GO:2000300)3.33504582
61membrane hyperpolarization (GO:0060081)3.31856562
62regulation of voltage-gated calcium channel activity (GO:1901385)3.31100421
63glutamate secretion (GO:0014047)3.29962914
64neurotransmitter-gated ion channel clustering (GO:0072578)3.28596255
65positive regulation of membrane potential (GO:0045838)3.26891374
66serotonin metabolic process (GO:0042428)3.24962896
67regulation of postsynaptic membrane potential (GO:0060078)3.24588352
68G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.21187785
69neuronal action potential propagation (GO:0019227)3.20569810
70regulation of excitatory postsynaptic membrane potential (GO:0060079)3.19405393
71membrane depolarization during action potential (GO:0086010)3.19398424
72axonal fasciculation (GO:0007413)3.18187991
73protein polyglutamylation (GO:0018095)3.16860528
74axoneme assembly (GO:0035082)3.15665254
75behavioral response to cocaine (GO:0048148)3.14736547
76synaptic vesicle maturation (GO:0016188)3.14558727
77postsynaptic membrane organization (GO:0001941)3.14057671
78positive regulation of neurotransmitter secretion (GO:0001956)3.13383449
79synaptic transmission, dopaminergic (GO:0001963)3.12013504
80regulation of synaptic vesicle transport (GO:1902803)3.09718445
81presynaptic membrane organization (GO:0097090)3.08750647
82righting reflex (GO:0060013)3.07702007
83behavioral fear response (GO:0001662)3.06376576
84behavioral defense response (GO:0002209)3.06376576
85response to auditory stimulus (GO:0010996)3.04006930
86striatum development (GO:0021756)3.03891313
87detection of abiotic stimulus (GO:0009582)3.03531098
88GMP metabolic process (GO:0046037)3.03387184
89gamma-aminobutyric acid signaling pathway (GO:0007214)3.01984194
90negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.00970622
91regulation of neurotransmitter secretion (GO:0046928)3.00416340
92locomotory exploration behavior (GO:0035641)2.98281509
93response to pheromone (GO:0019236)2.98255195
94detection of external stimulus (GO:0009581)2.97130486
95proline transport (GO:0015824)2.96830691
96positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.95244368
97synapse assembly (GO:0007416)2.95167025
98cAMP catabolic process (GO:0006198)2.94597002
99regulation of synaptic transmission, GABAergic (GO:0032228)2.94091630
100adult walking behavior (GO:0007628)2.93191020
101regulation of synaptic transmission, glutamatergic (GO:0051966)2.92723390
102behavioral response to ethanol (GO:0048149)2.91708704
103regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.91656620
104regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.91656620
105neuron recognition (GO:0008038)2.90398115
106fear response (GO:0042596)2.90103733
107central nervous system projection neuron axonogenesis (GO:0021952)2.90018579
108regulation of neuronal synaptic plasticity (GO:0048168)2.89696695
109regulation of long-term neuronal synaptic plasticity (GO:0048169)2.89045025
110C4-dicarboxylate transport (GO:0015740)2.88867758
111synaptic vesicle endocytosis (GO:0048488)2.88519834
112regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.88061389
113retinal ganglion cell axon guidance (GO:0031290)2.85703133
114axonemal dynein complex assembly (GO:0070286)2.85468220
115fucose catabolic process (GO:0019317)2.85347441
116L-fucose metabolic process (GO:0042354)2.85347441
117L-fucose catabolic process (GO:0042355)2.85347441
118cilium movement (GO:0003341)2.84585388
119central nervous system myelination (GO:0022010)2.84419295
120axon ensheathment in central nervous system (GO:0032291)2.84419295
121cilium organization (GO:0044782)2.83711903
122long-term synaptic potentiation (GO:0060291)2.83563252
123female mating behavior (GO:0060180)2.82059004
124reflex (GO:0060004)2.81950263
125detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.81776240
126membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80096929
127inner ear receptor stereocilium organization (GO:0060122)2.79980045
128cilium assembly (GO:0042384)2.79883792
129cell morphogenesis involved in neuron differentiation (GO:0048667)2.78327598
130cilium morphogenesis (GO:0060271)2.76995026
131regulation of neurotransmitter transport (GO:0051588)2.76253992
132regulation of G-protein coupled receptor protein signaling pathway (GO:0008277)2.76221642
133neural tube formation (GO:0001841)2.75981354
134central nervous system neuron axonogenesis (GO:0021955)2.75792088
135neurotransmitter transport (GO:0006836)2.75696302
136regulation of synapse maturation (GO:0090128)2.74834491
137transmission of nerve impulse (GO:0019226)2.74629141
138spinal cord development (GO:0021510)2.74376968
139neurotransmitter secretion (GO:0007269)2.74345219
140intraciliary transport (GO:0042073)2.73452756
141retina layer formation (GO:0010842)2.72572588
142glycosphingolipid biosynthetic process (GO:0006688)2.68868933
143positive regulation of synapse assembly (GO:0051965)2.68218919
144indole-containing compound metabolic process (GO:0042430)2.67733091
145adult behavior (GO:0030534)2.67376318
146neuromuscular synaptic transmission (GO:0007274)2.66828365
147indolalkylamine metabolic process (GO:0006586)2.65348388
148regulation of action potential (GO:0098900)2.58233547
149regulation of neurotransmitter levels (GO:0001505)2.57173586
150regulation of synapse structural plasticity (GO:0051823)2.56453225
151membrane depolarization (GO:0051899)2.56360333
152hindbrain development (GO:0030902)2.56289459
153synaptic transmission, cholinergic (GO:0007271)2.52729488
154positive regulation of oligodendrocyte differentiation (GO:0048714)2.52132450
155tryptophan catabolic process (GO:0006569)2.51833898
156indole-containing compound catabolic process (GO:0042436)2.51833898
157indolalkylamine catabolic process (GO:0046218)2.51833898
158regulation of respiratory system process (GO:0044065)2.51824847
159regulation of neurotransmitter uptake (GO:0051580)2.51358722

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.28813307
2GBX2_23144817_ChIP-Seq_PC3_Human4.27313511
3ZNF274_21170338_ChIP-Seq_K562_Hela2.70874070
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.66720720
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.64307884
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.60910106
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55018481
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.32068983
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.31455502
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.30131020
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.29957372
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.28687759
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.18506584
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.16448940
15* REST_21632747_ChIP-Seq_MESCs_Mouse2.16271840
16BMI1_23680149_ChIP-Seq_NPCS_Mouse2.15167551
17RNF2_18974828_ChIP-Seq_MESCs_Mouse2.15001526
18EZH2_18974828_ChIP-Seq_MESCs_Mouse2.15001526
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.09733011
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.06317890
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.04721373
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.04304633
23DROSHA_22980978_ChIP-Seq_HELA_Human2.01917380
24MTF2_20144788_ChIP-Seq_MESCs_Mouse1.98659576
25* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.97274004
26AR_21572438_ChIP-Seq_LNCaP_Human1.95065582
27SALL1_21062744_ChIP-ChIP_HESCs_Human1.93962096
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.89685147
29IGF1R_20145208_ChIP-Seq_DFB_Human1.89590848
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.89542678
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.84881952
32EWS_26573619_Chip-Seq_HEK293_Human1.83935769
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83739381
34P300_19829295_ChIP-Seq_ESCs_Human1.80717198
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.78699078
36POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78190788
37SMAD4_21799915_ChIP-Seq_A2780_Human1.76634215
38TAF15_26573619_Chip-Seq_HEK293_Human1.74469916
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.74300427
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69696343
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69089922
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.64695688
43FLI1_27457419_Chip-Seq_LIVER_Mouse1.62880719
44RNF2_27304074_Chip-Seq_NSC_Mouse1.60699418
45VDR_22108803_ChIP-Seq_LS180_Human1.55630887
46REST_18959480_ChIP-ChIP_MESCs_Mouse1.55204935
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.53460583
48TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.52261782
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.49796564
50NANOG_18555785_Chip-Seq_ESCs_Mouse1.49655749
51RARB_27405468_Chip-Seq_BRAIN_Mouse1.49013311
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.48573457
53TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47789995
54SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47095176
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.45308987
56CBP_20019798_ChIP-Seq_JUKART_Human1.45278165
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45278165
58FUS_26573619_Chip-Seq_HEK293_Human1.44880204
59E2F1_18555785_Chip-Seq_ESCs_Mouse1.44680808
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.40548107
61EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.40503420
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.39692985
63P53_22387025_ChIP-Seq_ESCs_Mouse1.38435903
64* STAT3_23295773_ChIP-Seq_U87_Human1.38269445
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.38268204
66CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36456922
67SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36125090
68ER_23166858_ChIP-Seq_MCF-7_Human1.32614873
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.32238388
70MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.31465849
71NR3C1_21868756_ChIP-Seq_MCF10A_Human1.30725258
72EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.28532722
73CMYC_18555785_Chip-Seq_ESCs_Mouse1.27931156
74BCAT_22108803_ChIP-Seq_LS180_Human1.27640562
75SUZ12_18555785_Chip-Seq_ESCs_Mouse1.27483369
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25564053
77SMAD_19615063_ChIP-ChIP_OVARY_Human1.24739573
78TCF4_23295773_ChIP-Seq_U87_Human1.24547617
79PCGF2_27294783_Chip-Seq_NPCs_Mouse1.23343745
80STAT3_18555785_Chip-Seq_ESCs_Mouse1.23020102
81P300_18555785_Chip-Seq_ESCs_Mouse1.22143192
82RUNX2_22187159_ChIP-Seq_PCA_Human1.20842226
83EZH2_27294783_Chip-Seq_NPCs_Mouse1.20624118
84AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20615714
85SOX2_21211035_ChIP-Seq_LN229_Gbm1.20503580
86IRF1_19129219_ChIP-ChIP_H3396_Human1.20444269
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20263235
88MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20081127
89AR_25329375_ChIP-Seq_VCAP_Human1.20080613
90P53_22127205_ChIP-Seq_FIBROBLAST_Human1.19219203
91SOX2_18555785_Chip-Seq_ESCs_Mouse1.18809699
92NMYC_18555785_Chip-Seq_ESCs_Mouse1.18646456
93TP53_22573176_ChIP-Seq_HFKS_Human1.18088002
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16368040
95CDX2_19796622_ChIP-Seq_MESCs_Mouse1.16091286
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14972084
97POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14972084
98HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14031697
99RUNX1_27457419_Chip-Seq_LIVER_Mouse1.13783252
100NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.13000243
101EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12979263
102TCF4_22108803_ChIP-Seq_LS180_Human1.12217249
103KDM2B_26808549_Chip-Seq_REH_Human1.12057540
104FLI1_21867929_ChIP-Seq_TH2_Mouse1.11312846
105PRDM14_20953172_ChIP-Seq_ESCs_Human1.10794455
106OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10774216
107RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10419676
108TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09744622
109* TAL1_26923725_Chip-Seq_HPCs_Mouse1.09669705
110OCT4_18555785_Chip-Seq_ESCs_Mouse1.08285002
111ARNT_22903824_ChIP-Seq_MCF-7_Human1.08256150
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07950133
113AHR_22903824_ChIP-Seq_MCF-7_Human1.07915790
114ZFX_18555785_Chip-Seq_ESCs_Mouse1.07502909
115TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05764155
116KLF4_18555785_Chip-Seq_ESCs_Mouse1.05239198
117CTCF_18555785_Chip-Seq_ESCs_Mouse1.05119836
118CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.04947759
119PU1_27457419_Chip-Seq_LIVER_Mouse1.04169592
120SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03565129
121KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03039082
122E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02435535
123SOX2_19829295_ChIP-Seq_ESCs_Human1.01295633
124NANOG_19829295_ChIP-Seq_ESCs_Human1.01295633
125JUN_21703547_ChIP-Seq_K562_Human1.01271870

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005551_abnormal_eye_electrophysiolog4.76940264
2MP0003880_abnormal_central_pattern4.19912258
3MP0003011_delayed_dark_adaptation3.83195421
4MP0004859_abnormal_synaptic_plasticity3.61211138
5MP0005423_abnormal_somatic_nervous3.16975672
6MP0005253_abnormal_eye_physiology3.13892317
7MP0006072_abnormal_retinal_apoptosis3.07769757
8MP0001188_hyperpigmentation2.93379014
9MP0003635_abnormal_synaptic_transmissio2.80479438
10MP0001968_abnormal_touch/_nociception2.71193409
11MP0009745_abnormal_behavioral_response2.67437556
12MP0004270_analgesia2.57349352
13MP0001486_abnormal_startle_reflex2.52758363
14MP0002063_abnormal_learning/memory/cond2.39257520
15MP0000569_abnormal_digit_pigmentation2.36028922
16MP0002822_catalepsy2.32303100
17MP0002572_abnormal_emotion/affect_behav2.29989149
18MP0001984_abnormal_olfaction2.29327688
19MP0009046_muscle_twitch2.23914437
20MP0002064_seizures2.22498679
21MP0002272_abnormal_nervous_system2.20335533
22MP0002734_abnormal_mechanical_nocicepti2.19920460
23MP0002735_abnormal_chemical_nociception2.17512776
24MP0010386_abnormal_urinary_bladder2.17496330
25MP0001986_abnormal_taste_sensitivity2.14889782
26MP0006276_abnormal_autonomic_nervous2.04772343
27MP0002736_abnormal_nociception_after2.01617873
28MP0002638_abnormal_pupillary_reflex2.00817763
29MP0006292_abnormal_olfactory_placode2.00121387
30MP0005646_abnormal_pituitary_gland1.81583800
31MP0005195_abnormal_posterior_eye1.80677504
32MP0001501_abnormal_sleep_pattern1.72799586
33MP0002067_abnormal_sensory_capabilities1.72349194
34MP0002557_abnormal_social/conspecific_i1.66499645
35MP0003121_genomic_imprinting1.65289863
36MP0003787_abnormal_imprinting1.64396263
37MP0002229_neurodegeneration1.62368466
38MP0002752_abnormal_somatic_nervous1.62023783
39MP0001502_abnormal_circadian_rhythm1.60467409
40MP0002102_abnormal_ear_morphology1.57701689
41MP0002882_abnormal_neuron_morphology1.55536959
42MP0001529_abnormal_vocalization1.55361899
43MP0001970_abnormal_pain_threshold1.55329682
44MP0005499_abnormal_olfactory_system1.52844828
45MP0005394_taste/olfaction_phenotype1.52844828
46MP0001440_abnormal_grooming_behavior1.52627308
47MP0005645_abnormal_hypothalamus_physiol1.51865645
48MP0004133_heterotaxia1.48989531
49MP0002184_abnormal_innervation1.48386477
50MP0008004_abnormal_stomach_pH1.43969249
51MP0004924_abnormal_behavior1.41681739
52MP0005386_behavior/neurological_phenoty1.41681739
53MP0000778_abnormal_nervous_system1.41411290
54MP0002733_abnormal_thermal_nociception1.39854718
55MP0002234_abnormal_pharynx_morphology1.37329384
56MP0005409_darkened_coat_color1.36502545
57MP0003283_abnormal_digestive_organ1.32626458
58MP0003136_yellow_coat_color1.31350592
59MP0001905_abnormal_dopamine_level1.30435793
60MP0001324_abnormal_eye_pigmentation1.27021807
61MP0004742_abnormal_vestibular_system1.26119272
62MP0005391_vision/eye_phenotype1.25864770
63MP0000427_abnormal_hair_cycle1.21663034
64MP0001963_abnormal_hearing_physiology1.20653573
65MP0008789_abnormal_olfactory_epithelium1.20314330
66MP0002090_abnormal_vision1.19422064
67MP0004142_abnormal_muscle_tone1.13943253
68MP0003879_abnormal_hair_cell1.13543052
69MP0004043_abnormal_pH_regulation1.13026199
70MP0000026_abnormal_inner_ear1.11772997
71MP0003950_abnormal_plasma_membrane1.10911878
72MP0005187_abnormal_penis_morphology1.10732240
73MP0002837_dystrophic_cardiac_calcinosis1.10585475
74MP0008569_lethality_at_weaning1.10387923
75MP0003195_calcinosis1.09748557
76MP0004147_increased_porphyrin_level1.07911750
77MP0002751_abnormal_autonomic_nervous1.03422771
78MP0000631_abnormal_neuroendocrine_gland1.00523756
79MP0002066_abnormal_motor_capabilities/c1.00225544
80MP0000955_abnormal_spinal_cord0.98289770
81MP0004885_abnormal_endolymph0.97625354
82MP0002938_white_spotting0.96303127
83MP0004811_abnormal_neuron_physiology0.93001290
84MP0003890_abnormal_embryonic-extraembry0.91664207
85MP0001485_abnormal_pinna_reflex0.89346517
86MP0002160_abnormal_reproductive_system0.85808560
87MP0003119_abnormal_digestive_system0.83896089
88MP0002876_abnormal_thyroid_physiology0.82027810
89MP0008875_abnormal_xenobiotic_pharmacok0.79757275
90MP0008872_abnormal_physiological_respon0.77758840
91MP0002653_abnormal_ependyma_morphology0.77167321
92MP0002152_abnormal_brain_morphology0.76977968
93MP0004145_abnormal_muscle_electrophysio0.76796936
94MP0005174_abnormal_tail_pigmentation0.76382965
95MP0003861_abnormal_nervous_system0.76374073
96MP0000566_synostosis0.75350074
97MP0005389_reproductive_system_phenotype0.75311192
98MP0008995_early_reproductive_senescence0.74802103
99MP0005410_abnormal_fertilization0.74353456
100MP0005379_endocrine/exocrine_gland_phen0.70149736
101MP0000647_abnormal_sebaceous_gland0.69599685
102MP0003633_abnormal_nervous_system0.67809059
103MP0005171_absent_coat_pigmentation0.67792852
104MP0009379_abnormal_foot_pigmentation0.66231414
105MP0002909_abnormal_adrenal_gland0.64928871
106MP0009780_abnormal_chondrocyte_physiolo0.64217655
107MP0002069_abnormal_eating/drinking_beha0.63535045
108MP0001664_abnormal_digestion0.62809680
109MP0000015_abnormal_ear_pigmentation0.62424347
110MP0001177_atelectasis0.60717787
111MP0003634_abnormal_glial_cell0.59232885
112MP0003122_maternal_imprinting0.57130845
113MP0002928_abnormal_bile_duct0.56963208
114MP0003137_abnormal_impulse_conducting0.56871140
115MP0003045_fibrosis0.56593768
116MP0004215_abnormal_myocardial_fiber0.55708015
117MP0003698_abnormal_male_reproductive0.54976681
118MP0003631_nervous_system_phenotype0.53837461
119MP0004484_altered_response_of0.52324175
120MP0002277_abnormal_respiratory_mucosa0.51247024
121MP0008877_abnormal_DNA_methylation0.50594179
122MP0003938_abnormal_ear_development0.50128460

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)8.51872206
2Bony spicule pigmentary retinopathy (HP:0007737)6.73428796
3Absent rod-and cone-mediated responses on ERG (HP:0007688)6.23061406
4Abnormal rod and cone electroretinograms (HP:0008323)6.14125188
5Abnormality of macular pigmentation (HP:0008002)5.07786166
6Dyschromatopsia (HP:0007641)5.00731299
7Attenuation of retinal blood vessels (HP:0007843)4.88012706
8Central scotoma (HP:0000603)4.75339838
9Decreased central vision (HP:0007663)4.74904074
10Focal motor seizures (HP:0011153)4.73716393
11Chorioretinal atrophy (HP:0000533)4.44010217
12Pendular nystagmus (HP:0012043)4.42197081
13Pigmentary retinal degeneration (HP:0001146)4.26567314
14Febrile seizures (HP:0002373)4.13934250
15Scotoma (HP:0000575)4.05982898
16Abolished electroretinogram (ERG) (HP:0000550)4.01024841
17Gait imbalance (HP:0002141)3.85435588
18Severe visual impairment (HP:0001141)3.77866602
19Medial flaring of the eyebrow (HP:0010747)3.77523988
20Congenital primary aphakia (HP:0007707)3.70910212
21Abnormal ciliary motility (HP:0012262)3.65993366
22Epileptic encephalopathy (HP:0200134)3.59670826
23Photophobia (HP:0000613)3.52816594
24Dynein arm defect of respiratory motile cilia (HP:0012255)3.47109881
25Absent/shortened dynein arms (HP:0200106)3.47109881
26Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.46285191
27Nephrogenic diabetes insipidus (HP:0009806)3.44843834
28Increased corneal curvature (HP:0100692)3.43619992
29Keratoconus (HP:0000563)3.43619992
30Abnormal respiratory motile cilium physiology (HP:0012261)3.42707179
31Retinitis pigmentosa (HP:0000510)3.28914737
32Type II diabetes mellitus (HP:0005978)3.20293853
33Myokymia (HP:0002411)3.18281542
34Focal seizures (HP:0007359)3.04336843
35True hermaphroditism (HP:0010459)2.98027678
36Abnormal respiratory motile cilium morphology (HP:0005938)2.96663102
37Abnormal respiratory epithelium morphology (HP:0012253)2.96663102
38Type II lissencephaly (HP:0007260)2.95144105
39Congenital sensorineural hearing impairment (HP:0008527)2.94278170
40Choroideremia (HP:0001139)2.89662237
41Hemiparesis (HP:0001269)2.83870080
42Limb dystonia (HP:0002451)2.79439162
43Poor coordination (HP:0002370)2.76175783
44Vaginal atresia (HP:0000148)2.71870316
45Pancreatic fibrosis (HP:0100732)2.69651616
46Genital tract atresia (HP:0001827)2.67112147
47Drooling (HP:0002307)2.63904780
48Lissencephaly (HP:0001339)2.62571178
49Macular degeneration (HP:0000608)2.61162605
50Cone-rod dystrophy (HP:0000548)2.59479846
51Abnormality of the renal cortex (HP:0011035)2.55418661
52Progressive cerebellar ataxia (HP:0002073)2.54797929
53Constricted visual fields (HP:0001133)2.53340171
54Abnormal drinking behavior (HP:0030082)2.49195546
55Polydipsia (HP:0001959)2.49195546
56Pancreatic cysts (HP:0001737)2.38935996
57Broad-based gait (HP:0002136)2.38146207
58Excessive salivation (HP:0003781)2.37863295
59Decreased electroretinogram (ERG) amplitude (HP:0000654)2.36422706
60Optic disc pallor (HP:0000543)2.35646944
61Tubular atrophy (HP:0000092)2.33888082
62Gaze-evoked nystagmus (HP:0000640)2.33257702
63Aplasia/Hypoplasia of the lens (HP:0008063)2.31886442
64Polyphagia (HP:0002591)2.30455628
65Hypothermia (HP:0002045)2.25709397
66Hyperventilation (HP:0002883)2.21822774
67Epileptiform EEG discharges (HP:0011182)2.21347441
68Sclerocornea (HP:0000647)2.16834374
69Pachygyria (HP:0001302)2.14797272
70Cerebellar dysplasia (HP:0007033)2.13986322
71EEG with generalized epileptiform discharges (HP:0011198)2.13628152
72Atonic seizures (HP:0010819)2.12630994
73Nephronophthisis (HP:0000090)2.11897621
74Vitreoretinal degeneration (HP:0000655)2.11645140
75Hypsarrhythmia (HP:0002521)2.11587682
76Dysdiadochokinesis (HP:0002075)2.10586212
77Molar tooth sign on MRI (HP:0002419)2.10496519
78Abnormality of midbrain morphology (HP:0002418)2.10496519
79Bile duct proliferation (HP:0001408)2.09883229
80Abnormal biliary tract physiology (HP:0012439)2.09883229
81Visual hallucinations (HP:0002367)2.09505767
82Anencephaly (HP:0002323)2.08666294
83Action tremor (HP:0002345)2.08099844
84Occipital encephalocele (HP:0002085)2.07667250
85Tubulointerstitial nephritis (HP:0001970)2.06956089
86Optic nerve hypoplasia (HP:0000609)2.04766156
87Rhinitis (HP:0012384)2.04103282
88Generalized tonic-clonic seizures (HP:0002069)2.02781595
89Agitation (HP:0000713)2.00875373
90Specific learning disability (HP:0001328)1.99522853
91Cystic liver disease (HP:0006706)1.99464389
92Absence seizures (HP:0002121)1.99111568
93Progressive inability to walk (HP:0002505)1.96183098
94Abnormality of the labia minora (HP:0012880)1.95180226
95Dialeptic seizures (HP:0011146)1.93196262
96Fetal akinesia sequence (HP:0001989)1.92376851
97Status epilepticus (HP:0002133)1.90914124
98Intestinal atresia (HP:0011100)1.89390548
99Male pseudohermaphroditism (HP:0000037)1.89229878
100Posterior subcapsular cataract (HP:0007787)1.87675314
101Aplasia/Hypoplasia of the tibia (HP:0005772)1.86905534
102Genetic anticipation (HP:0003743)1.86470273
103Polyuria (HP:0000103)1.86414866
104Truncal ataxia (HP:0002078)1.84432159
105Large for gestational age (HP:0001520)1.84370973
106Furrowed tongue (HP:0000221)1.82539106
107Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.80790213
108Chronic hepatic failure (HP:0100626)1.79155135
109Narrow forehead (HP:0000341)1.77718419
110Abnormal eating behavior (HP:0100738)1.77640530
111Morphological abnormality of the pyramidal tract (HP:0002062)1.76310073
112Astigmatism (HP:0000483)1.73701147
113Abnormal EKG (HP:0003115)1.72870238
114Renal cortical cysts (HP:0000803)1.72835072
115Hemiplegia (HP:0002301)1.71755733
116Protruding tongue (HP:0010808)1.71325656
117Postaxial hand polydactyly (HP:0001162)1.70893646
118Congenital hepatic fibrosis (HP:0002612)1.70152799
119Postaxial foot polydactyly (HP:0001830)1.70139898
120Abnormality of the renal medulla (HP:0100957)1.69445623
121Abnormal hair whorl (HP:0010721)1.68888890
122Amblyopia (HP:0000646)1.68370198
123Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.66761999
124Degeneration of the lateral corticospinal tracts (HP:0002314)1.66761999
125Dyskinesia (HP:0100660)1.66345148
126Aplasia/Hypoplasia of the tongue (HP:0010295)1.65724205
127Absent speech (HP:0001344)1.64262728
128Hypoplasia of the fovea (HP:0007750)1.61898900
129Aplasia/Hypoplasia of the fovea (HP:0008060)1.61898900
130Inability to walk (HP:0002540)1.61078171
131Chromosomal breakage induced by crosslinking agents (HP:0003221)1.60830655
132Urinary bladder sphincter dysfunction (HP:0002839)1.59963279
133Prolonged QT interval (HP:0001657)1.59425324
134Chorioretinal coloboma (HP:0000567)1.56438998
135Abnormality of the corticospinal tract (HP:0002492)1.56010059
136Anxiety (HP:0000739)1.55923297
137Septo-optic dysplasia (HP:0100842)1.55709791
138Retinal dysplasia (HP:0007973)1.55409366
139Ventricular fibrillation (HP:0001663)1.54637419
140Fair hair (HP:0002286)1.54350699
141Poor eye contact (HP:0000817)1.53995405

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.33626470
2EPHA43.95512328
3CASK3.87787642
4NTRK33.77457067
5GRK13.49303008
6TNIK3.25245257
7MAP2K72.89377088
8MARK12.46508942
9STK162.42216674
10MAP4K22.35790817
11RIPK42.15595299
12MAP3K42.11466244
13BMPR21.99941451
14MAP3K121.96721897
15MAPK131.80324757
16ADRBK21.72774728
17PBK1.70036682
18NTRK21.65220903
19DAPK21.63162652
20PINK11.52321240
21MINK11.44008115
22WNK41.43631876
23DYRK21.39280791
24TRIM281.36680342
25CSNK1G21.35030628
26PRPF4B1.34352902
27STK381.31894037
28CDK191.29050866
29PLK21.28577899
30NUAK11.28256358
31MUSK1.27921235
32IRAK21.23407456
33SIK21.23392784
34PNCK1.22239983
35ACVR1B1.15632928
36CAMK2A1.15422928
37MAP3K91.12953251
38OXSR11.11868162
39SGK21.11149588
40MAP2K41.11120151
41PRKCG1.10995124
42PAK31.10657692
43FES1.08984866
44GRK51.07498058
45CDK51.06916615
46NEK61.06910181
47FGFR21.06864863
48CSNK1G31.05485667
49SGK4941.03891914
50SGK2231.03891914
51TNK21.02447648
52AKT31.02043481
53MKNK21.01639802
54CDK30.99033692
55MAPK150.97478419
56PAK60.97369767
57CSNK1G10.96805276
58CCNB10.93537397
59CAMK2B0.92212425
60BCR0.90248348
61CSNK1A1L0.89376615
62PRKCE0.87596988
63PIK3CG0.86424044
64DYRK1A0.83685587
65CAMK10.83166690
66INSRR0.82759618
67CAMK2D0.79746321
68CAMKK10.79742668
69DAPK10.79351403
70SIK30.78658820
71WNK30.77514166
72SGK10.76547062
73NTRK10.76213380
74ZAK0.75697757
75PKN10.74534569
76TLK10.74156029
77NME10.73822719
78DYRK30.70380464
79TXK0.68820503
80CDC42BPA0.68034988
81EPHB20.66701706
82IRAK30.63615449
83STK38L0.62533749
84PHKG20.61872103
85PHKG10.61872103
86KSR10.61699260
87ADRBK10.61302531
88STK110.61048761
89MAP3K130.60658794
90BCKDK0.60285145
91LMTK20.59693334
92CAMK40.55486421
93PIK3CA0.55167356
94PRKD30.54105708
95TGFBR10.53599194
96CAMK2G0.53131690
97TAOK30.51172240
98ERBB30.51033884
99PRKACA0.50878941
100EIF2AK20.50170710
101SGK30.49786607
102PRKCH0.48830857
103MAPKAPK50.48750019
104STK390.48737547
105UHMK10.46817456
106ERBB20.45949475
107MARK20.45903564
108PLK40.45785230
109MAPK70.45513477
110CSNK1A10.44712176
111GRK70.44532605
112VRK10.44444111
113PRKCB0.43374280
114PRKCZ0.43313038
115IRAK10.41881006
116RPS6KA50.41857548
117EPHA30.41765237
118CDK180.41720093
119MKNK10.41520717
120BRD40.40948842
121ARAF0.40948532
122CSNK1D0.40654292
123CAMKK20.40650710
124PTK2B0.40327927
125PRKCA0.40073813
126PRKD20.38788354
127BMPR1B0.38667148
128TIE10.38633691
129MAPK120.38593164
130BRAF0.38447756
131PRKG10.37328788
132PRKAA10.36764464
133FGR0.36563734
134TSSK60.34616732
135RPS6KA40.32803716
136RPS6KA30.31281436

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047448.68880356
2Nicotine addiction_Homo sapiens_hsa050333.50889553
3Olfactory transduction_Homo sapiens_hsa047403.19078485
4Synaptic vesicle cycle_Homo sapiens_hsa047212.73608567
5Morphine addiction_Homo sapiens_hsa050322.70780486
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.69041022
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.56487846
8GABAergic synapse_Homo sapiens_hsa047272.48179468
9Butanoate metabolism_Homo sapiens_hsa006502.34798733
10Circadian entrainment_Homo sapiens_hsa047132.34421216
11Glutamatergic synapse_Homo sapiens_hsa047242.32612584
12Maturity onset diabetes of the young_Homo sapiens_hsa049502.08943495
13Taste transduction_Homo sapiens_hsa047421.95360875
14Serotonergic synapse_Homo sapiens_hsa047261.90352308
15Amphetamine addiction_Homo sapiens_hsa050311.86998635
16Insulin secretion_Homo sapiens_hsa049111.81445944
17Dopaminergic synapse_Homo sapiens_hsa047281.81318827
18Cholinergic synapse_Homo sapiens_hsa047251.80032621
19Salivary secretion_Homo sapiens_hsa049701.78351494
20Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69819682
21Long-term potentiation_Homo sapiens_hsa047201.68436918
22Nitrogen metabolism_Homo sapiens_hsa009101.51031954
23Calcium signaling pathway_Homo sapiens_hsa040201.50444444
24Protein export_Homo sapiens_hsa030601.47850086
25Renin secretion_Homo sapiens_hsa049241.47657723
26Collecting duct acid secretion_Homo sapiens_hsa049661.47272901
27Gastric acid secretion_Homo sapiens_hsa049711.40996525
28Cocaine addiction_Homo sapiens_hsa050301.40426469
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36302481
30Linoleic acid metabolism_Homo sapiens_hsa005911.35756150
31Aldosterone synthesis and secretion_Homo sapiens_hsa049251.33516567
32Oxytocin signaling pathway_Homo sapiens_hsa049211.29580665
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26972246
34Long-term depression_Homo sapiens_hsa047301.21826390
35Tryptophan metabolism_Homo sapiens_hsa003801.18413937
36alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17981737
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16785336
38cAMP signaling pathway_Homo sapiens_hsa040241.16766131
39Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.08899336
40Peroxisome_Homo sapiens_hsa041461.06884296
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.05054973
42Selenocompound metabolism_Homo sapiens_hsa004501.04769498
43GnRH signaling pathway_Homo sapiens_hsa049121.03314372
44Propanoate metabolism_Homo sapiens_hsa006401.02328996
45Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.02226845
46Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.99334033
47Circadian rhythm_Homo sapiens_hsa047100.98543835
48Cardiac muscle contraction_Homo sapiens_hsa042600.98344881
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.98143090
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97179995
51Primary bile acid biosynthesis_Homo sapiens_hsa001200.95098738
52Steroid biosynthesis_Homo sapiens_hsa001000.92711319
53Oxidative phosphorylation_Homo sapiens_hsa001900.90429347
54cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88419436
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.86994278
56Axon guidance_Homo sapiens_hsa043600.86856304
57Caffeine metabolism_Homo sapiens_hsa002320.84301487
58Melanogenesis_Homo sapiens_hsa049160.83836889
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81592181
60Basal transcription factors_Homo sapiens_hsa030220.79507312
61Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.76838211
62Vascular smooth muscle contraction_Homo sapiens_hsa042700.76462855
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.73451739
64Ovarian steroidogenesis_Homo sapiens_hsa049130.73127365
65RNA polymerase_Homo sapiens_hsa030200.71406493
66Pancreatic secretion_Homo sapiens_hsa049720.71213506
67Gap junction_Homo sapiens_hsa045400.70749463
68Alzheimers disease_Homo sapiens_hsa050100.70665078
69Vibrio cholerae infection_Homo sapiens_hsa051100.69835141
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64141173
71Ras signaling pathway_Homo sapiens_hsa040140.64107234
72ErbB signaling pathway_Homo sapiens_hsa040120.64084506
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63391925
74beta-Alanine metabolism_Homo sapiens_hsa004100.63335498
75Homologous recombination_Homo sapiens_hsa034400.62907261
76RNA degradation_Homo sapiens_hsa030180.62370874
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62333009
78Huntingtons disease_Homo sapiens_hsa050160.62300409
79Inositol phosphate metabolism_Homo sapiens_hsa005620.61629234
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61252220
81Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61179957
82Parkinsons disease_Homo sapiens_hsa050120.57367845
83Alcoholism_Homo sapiens_hsa050340.55109243
84Choline metabolism in cancer_Homo sapiens_hsa052310.54181693
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.52765594
86Estrogen signaling pathway_Homo sapiens_hsa049150.52153977
87Sphingolipid metabolism_Homo sapiens_hsa006000.51827667
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.51661458
89Type II diabetes mellitus_Homo sapiens_hsa049300.50991729
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50629473
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48760842
92Purine metabolism_Homo sapiens_hsa002300.48740694
93Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48528651
94Dilated cardiomyopathy_Homo sapiens_hsa054140.48119942
95Histidine metabolism_Homo sapiens_hsa003400.47546990
96MAPK signaling pathway_Homo sapiens_hsa040100.47154368
97Ether lipid metabolism_Homo sapiens_hsa005650.45825167
98Glioma_Homo sapiens_hsa052140.43859178
99Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43645771
100Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42006832
101Wnt signaling pathway_Homo sapiens_hsa043100.40005158
102Fanconi anemia pathway_Homo sapiens_hsa034600.39840223
103Chemical carcinogenesis_Homo sapiens_hsa052040.39710830
104Fatty acid metabolism_Homo sapiens_hsa012120.39358270
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.38399136
106Glycerolipid metabolism_Homo sapiens_hsa005610.38385895
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37994630
108Type I diabetes mellitus_Homo sapiens_hsa049400.36313171
109Rheumatoid arthritis_Homo sapiens_hsa053230.36062059
110Fatty acid elongation_Homo sapiens_hsa000620.36053225
111Glycerophospholipid metabolism_Homo sapiens_hsa005640.34776440
112Metabolic pathways_Homo sapiens_hsa011000.33938186
113Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.33814061
114Oocyte meiosis_Homo sapiens_hsa041140.33486014
115Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33439094
116Bile secretion_Homo sapiens_hsa049760.33115274
117Rap1 signaling pathway_Homo sapiens_hsa040150.32846061
118African trypanosomiasis_Homo sapiens_hsa051430.31815101
119Thyroid hormone synthesis_Homo sapiens_hsa049180.31002575
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.30096606
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.29667849
122Dorso-ventral axis formation_Homo sapiens_hsa043200.29512346
123Chemokine signaling pathway_Homo sapiens_hsa040620.29478694
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28020777
125Melanoma_Homo sapiens_hsa052180.27342872
126Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26626144
127Glucagon signaling pathway_Homo sapiens_hsa049220.24266301
128Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.24210171
129Autoimmune thyroid disease_Homo sapiens_hsa053200.21757561
130Mineral absorption_Homo sapiens_hsa049780.21667185
131Hedgehog signaling pathway_Homo sapiens_hsa043400.18983464
132ABC transporters_Homo sapiens_hsa020100.17951336
133Regulation of autophagy_Homo sapiens_hsa041400.16255552
134Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.16047495
135Thyroid hormone signaling pathway_Homo sapiens_hsa049190.15617721

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