WDR26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytoplasmic mRNA processing body assembly (GO:0033962)5.05424410
2mitotic sister chromatid cohesion (GO:0007064)3.62841757
3detection of molecule of bacterial origin (GO:0032490)3.53421871
4protein localization to endosome (GO:0036010)3.52551263
5negative regulation of erythrocyte differentiation (GO:0045647)3.51708339
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.44601737
7negative regulation of cell killing (GO:0031342)3.44601737
8growth hormone receptor signaling pathway (GO:0060396)3.40875024
9phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.39238519
10NLS-bearing protein import into nucleus (GO:0006607)3.21453381
11cellular extravasation (GO:0045123)3.21353248
12regulation of necroptotic process (GO:0060544)3.18185160
13monoubiquitinated protein deubiquitination (GO:0035520)3.17994401
14positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.16041372
15regulation of RNA export from nucleus (GO:0046831)3.15534191
16embryonic process involved in female pregnancy (GO:0060136)3.08710594
17regulation of histone H3-K27 methylation (GO:0061085)3.08485169
18positive regulation of histone deacetylation (GO:0031065)3.02674377
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.02367734
20modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.02367734
21positive regulation by organism of defense response of other organism involved in symbiotic interact3.02367734
22modulation by symbiont of host immune response (GO:0052553)3.02367734
23positive regulation by symbiont of host defense response (GO:0052509)3.02367734
24modulation by symbiont of host defense response (GO:0052031)3.02367734
25regulation of interferon-beta biosynthetic process (GO:0045357)3.01001232
26hypotonic response (GO:0006971)2.98991345
27cellular response to growth hormone stimulus (GO:0071378)2.91035984
28detection of other organism (GO:0098543)2.87093364
29antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.86937471
30detection of external biotic stimulus (GO:0098581)2.86425719
31histone H3-K36 demethylation (GO:0070544)2.86268455
32regulation of nucleobase-containing compound transport (GO:0032239)2.85342941
33regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.84073345
34positive thymic T cell selection (GO:0045059)2.83342888
35cortical actin cytoskeleton organization (GO:0030866)2.80687157
36response to muramyl dipeptide (GO:0032495)2.79320288
37cell adhesion mediated by integrin (GO:0033627)2.78926960
38histone H3-K9 demethylation (GO:0033169)2.77804022
39positive regulation of receptor recycling (GO:0001921)2.76371542
40nuclear pore organization (GO:0006999)2.72340244
41definitive hemopoiesis (GO:0060216)2.70884370
42protein dealkylation (GO:0008214)2.70485863
43protein demethylation (GO:0006482)2.70485863
44regulation of clathrin-mediated endocytosis (GO:2000369)2.69669355
45regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.69227950
46positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.69227950
47regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.69150067
48positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.69150067
49positive regulation of gamma-delta T cell activation (GO:0046645)2.68068759
50positive regulation of granulocyte differentiation (GO:0030854)2.67911128
51erythrocyte development (GO:0048821)2.66341938
52negative regulation of necroptotic process (GO:0060546)2.64546366
53B cell receptor signaling pathway (GO:0050853)2.62810476
54RNA stabilization (GO:0043489)2.62608495
55mRNA stabilization (GO:0048255)2.62608495
56germ cell migration (GO:0008354)2.62242088
57cellular response to ethanol (GO:0071361)2.61063718
58response to peptidoglycan (GO:0032494)2.60691738
59regulation of gamma-delta T cell differentiation (GO:0045586)2.57846016
60embryonic retina morphogenesis in camera-type eye (GO:0060059)2.55733738
61regulation of NFAT protein import into nucleus (GO:0051532)2.55452798
62positive regulation of cellular amide metabolic process (GO:0034250)2.53590725
63hepatocyte apoptotic process (GO:0097284)2.52511606
64microglial cell activation (GO:0001774)2.52453286
65regulation of T cell tolerance induction (GO:0002664)2.49560728
66positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.49145855
67detection of bacterium (GO:0016045)2.48261412
68macrophage activation (GO:0042116)2.47754077
69neutrophil activation involved in immune response (GO:0002283)2.47582616
70histone H3-K4 trimethylation (GO:0080182)2.45899033
71insulin-like growth factor receptor signaling pathway (GO:0048009)2.45796657
72detection of biotic stimulus (GO:0009595)2.45194187
73hippo signaling (GO:0035329)2.44741284
74pre-miRNA processing (GO:0031054)2.43273717
75response to laminar fluid shear stress (GO:0034616)2.42404435
76positive regulation of mitotic sister chromatid separation (GO:1901970)2.41603413
77positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.41603413
78positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.41603413
79corticosteroid receptor signaling pathway (GO:0031958)2.41595904
80positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.41509412
81I-kappaB phosphorylation (GO:0007252)2.41438349
82pathway-restricted SMAD protein phosphorylation (GO:0060389)2.40061144
83negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.38827263
84germinal center formation (GO:0002467)2.38805210
85negative regulation of fatty acid transport (GO:2000192)2.38454357
86nuclear pore complex assembly (GO:0051292)2.37659534
87response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.37651578
88response to host (GO:0075136)2.37651578
89response to host defenses (GO:0052200)2.37651578
90platelet-derived growth factor receptor signaling pathway (GO:0048008)2.36956664
91glucocorticoid receptor signaling pathway (GO:0042921)2.36797324
92macrophage activation involved in immune response (GO:0002281)2.36541260
93regulation of protein polyubiquitination (GO:1902914)2.36191646
94mannose metabolic process (GO:0006013)2.34968284
95cortical cytoskeleton organization (GO:0030865)2.34473100
96myeloid cell development (GO:0061515)2.33944260
97negative regulation of interleukin-12 production (GO:0032695)2.33888055
983-UTR-mediated mRNA stabilization (GO:0070935)2.33825418
99interkinetic nuclear migration (GO:0022027)2.33507541
100negative regulation of T cell mediated immunity (GO:0002710)2.32777247
101positive regulation of mRNA catabolic process (GO:0061014)2.32430584
102negative regulation of protein localization to plasma membrane (GO:1903077)2.28993314
103regulation of interleukin-12 biosynthetic process (GO:0045075)2.28689599
104dosage compensation (GO:0007549)2.27842629
105regulation of gamma-delta T cell activation (GO:0046643)2.27578014
106JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.26684723
107antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.26411946
108positive regulation of p38MAPK cascade (GO:1900745)2.25807540
109regulation of sister chromatid cohesion (GO:0007063)2.24758048
110megakaryocyte development (GO:0035855)2.24274966
111nerve growth factor signaling pathway (GO:0038180)2.24256946
112negative regulation of lymphocyte mediated immunity (GO:0002707)2.24076739
113response to host immune response (GO:0052572)2.23018812
114response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.23018812
115positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.22966162
116negative thymic T cell selection (GO:0045060)2.22897984
117negative regulation of anoikis (GO:2000811)2.22565450
118macroautophagy (GO:0016236)2.22330525
119stress fiber assembly (GO:0043149)2.21443416
120regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.20849450
121leukocyte aggregation (GO:0070486)2.19798269
122histone lysine demethylation (GO:0070076)2.18803238
123pinocytosis (GO:0006907)2.17514541
124positive T cell selection (GO:0043368)2.16829287
125negative T cell selection (GO:0043383)2.16677686
126neutrophil mediated immunity (GO:0002446)2.16581285
127coronary vasculature morphogenesis (GO:0060977)2.16105374
128peptidyl-lysine trimethylation (GO:0018023)2.15338516
129thymic T cell selection (GO:0045061)2.15143124
130regulation of macrophage cytokine production (GO:0010935)2.15138871
131regulation of platelet aggregation (GO:0090330)2.14893568
132negative regulation of granulocyte differentiation (GO:0030853)2.14675075
133B cell homeostasis (GO:0001782)2.14564138
134regulation of establishment of cell polarity (GO:2000114)2.12110242
135iron ion import (GO:0097286)2.11086505
136positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.09635912
137negative regulation of B cell proliferation (GO:0030889)2.09567116
138peptidyl-threonine modification (GO:0018210)2.08486222
139response to fluid shear stress (GO:0034405)2.08014418
140apoptotic cell clearance (GO:0043277)2.07937901
141embryonic viscerocranium morphogenesis (GO:0048703)2.07715003
142regulation of transforming growth factor beta2 production (GO:0032909)2.07495427
143cytoskeletal anchoring at plasma membrane (GO:0007016)2.07491098
144regulation of B cell receptor signaling pathway (GO:0050855)2.06989013
145peptidyl-threonine phosphorylation (GO:0018107)2.06567395
146regulation of mRNA catabolic process (GO:0061013)2.06260863
147response to arsenic-containing substance (GO:0046685)2.05149338
148face morphogenesis (GO:0060325)2.04923953
149substrate-dependent cell migration (GO:0006929)2.04801736
150regulation of mRNA stability (GO:0043488)2.04761150
151negative regulation of translation, ncRNA-mediated (GO:0040033)2.04612225
152regulation of translation, ncRNA-mediated (GO:0045974)2.04612225
153negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.04612225
154positive regulation of cellular response to insulin stimulus (GO:1900078)2.04540221
155histone H2A monoubiquitination (GO:0035518)2.04511048
156tolerance induction (GO:0002507)2.03991338
157positive regulation of SMAD protein import into nucleus (GO:0060391)2.02265960
158heterotypic cell-cell adhesion (GO:0034113)2.00050149
159activation of JUN kinase activity (GO:0007257)1.99832576
160histone H3-K4 methylation (GO:0051568)1.98468883
161histone demethylation (GO:0016577)1.98007198

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.49255039
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.70716918
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.48057066
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.01433774
5FOXM1_23109430_ChIP-Seq_U2OS_Human2.84011145
6GATA1_22025678_ChIP-Seq_K562_Human2.51060489
7STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.45981295
8* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.36799359
9STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.24775012
10* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.20735342
11IRF8_27001747_Chip-Seq_BMDM_Mouse2.14808840
12FOXO3_23340844_ChIP-Seq_DLD1_Human2.13979206
13Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.09092732
14* TCF7_22412390_ChIP-Seq_EML_Mouse2.04109598
15* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.96161732
16TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.91991616
17MYC_22102868_ChIP-Seq_BL_Human1.91560887
18SMAD_19615063_ChIP-ChIP_OVARY_Human1.90793442
19MYB_21317192_ChIP-Seq_ERMYB_Mouse1.88672050
20KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.85019962
21KDM2B_26808549_Chip-Seq_DND41_Human1.83041415
22TP63_17297297_ChIP-ChIP_HaCaT_Human1.80969472
23RUNX_20019798_ChIP-Seq_JUKART_Human1.80463496
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.73654040
25TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.73352063
26VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.69947662
27* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.66998625
28CLOCK_20551151_ChIP-Seq_293T_Human1.66852050
29IRF8_22096565_ChIP-ChIP_GC-B_Human1.66042797
30* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.65962010
31MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.65499064
32ZNF217_24962896_ChIP-Seq_MCF-7_Human1.64630884
33BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.60453384
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.60040976
35* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.57783333
36BP1_19119308_ChIP-ChIP_Hs578T_Human1.56483974
37IRF8_21731497_ChIP-ChIP_J774_Mouse1.56040240
38VDR_24787735_ChIP-Seq_THP-1_Human1.52430968
39GATA1_19941826_ChIP-Seq_K562_Human1.51903404
40KDM2B_26808549_Chip-Seq_SUP-B15_Human1.50743231
41TP53_16413492_ChIP-PET_HCT116_Human1.49286905
42GATA1_19941827_ChIP-Seq_MEL_Mouse1.47192232
43RUNX1_22412390_ChIP-Seq_EML_Mouse1.46290497
44SCL_19346495_ChIP-Seq_HPC-7_Human1.44681164
45PPAR_26484153_Chip-Seq_NCI-H1993_Human1.43755503
46MAF_26560356_Chip-Seq_TH1_Human1.41939108
47MYB_26560356_Chip-Seq_TH2_Human1.41444852
48KDM2B_26808549_Chip-Seq_JURKAT_Human1.39557551
49* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.38394309
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.37152098
51* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.36984078
52* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.36461691
53TRIM28_21343339_ChIP-Seq_HEK293_Human1.36298960
54VDR_21846776_ChIP-Seq_THP-1_Human1.34776022
55CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.31944539
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.31916202
57* BRD4_25478319_ChIP-Seq_HGPS_Human1.30417694
58* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.30085269
59* VDR_24763502_ChIP-Seq_THP-1_Human1.29581887
60* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.29384742
61KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.28773933
62SPI1_23127762_ChIP-Seq_K562_Human1.28151010
63UTX_26944678_Chip-Seq_JUKART_Human1.27308845
64* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.25828497
65* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.25163291
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.24281466
67GATA2_19941826_ChIP-Seq_K562_Human1.24026219
68MYB_26560356_Chip-Seq_TH1_Human1.23772956
69FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.23531867
70GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.22691081
71SPI1_23547873_ChIP-Seq_NB4_Human1.22449091
72* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.21961044
73GATA2_21666600_ChIP-Seq_HMVEC_Human1.21363667
74SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.19693937
75SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.19693937
76* PU_27001747_Chip-Seq_BMDM_Mouse1.19349581
77RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.18635533
78CJUN_26792858_Chip-Seq_BT549_Human1.17788431
79SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.17323620
80RXR_22108803_ChIP-Seq_LS180_Human1.17166343
81SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16686379
82NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.16626169
83ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.16113760
84E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.15311968
85FOXA2_19822575_ChIP-Seq_HepG2_Human1.15245396
86STAT4_19710469_ChIP-ChIP_TH1__Mouse1.15230751
87* WT1_19549856_ChIP-ChIP_CCG9911_Human1.14917817
88SOX2_27498859_Chip-Seq_STOMACH_Mouse1.14619662
89* ELK3_25401928_ChIP-Seq_HUVEC_Human1.13936273
90E2F7_22180533_ChIP-Seq_HELA_Human1.12685934
91HIF1A_21447827_ChIP-Seq_MCF-7_Human1.11829624
92TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10765152
93SALL4_18804426_ChIP-ChIP_XEN_Mouse1.10668750
94* UBF1/2_26484160_Chip-Seq_HMECs_Human1.10319332
95ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10177309
96NCOR1_26117541_ChIP-Seq_K562_Human1.10121049
97FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09193816
98* GATA1_19941827_ChIP-Seq_MEL86_Mouse1.08792385
99ESR2_21235772_ChIP-Seq_MCF-7_Human1.08201705
100RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.08052752
101GATA6_25053715_ChIP-Seq_YYC3_Human1.07956195
102GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07297800
103GATA2_22383799_ChIP-Seq_G1ME_Mouse1.07133212
104* ESR1_20079471_ChIP-ChIP_T-47D_Human1.06351814
105KDM2B_26808549_Chip-Seq_K562_Human1.05666498
106IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.05303883
107GATA3_27048872_Chip-Seq_THYMUS_Human1.04378453
108ESR1_21235772_ChIP-Seq_MCF-7_Human1.03803030
109SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03560457
110SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.03341401
111CTNNB1_20460455_ChIP-Seq_HCT116_Human1.01783517
112PKCTHETA_26484144_Chip-Seq_BREAST_Human1.01352057
113STAT6_21828071_ChIP-Seq_BEAS2B_Human1.00248193
114TBX20_22080862_ChIP-Seq_HEART_Mouse1.00063698
115TBX20_22328084_ChIP-Seq_HEART_Mouse1.00063698
116TFEB_21752829_ChIP-Seq_HELA_Human0.97394273
117PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96206378
118IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.95476977
119TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95190834
120* CHD1_26751641_Chip-Seq_LNCaP_Human0.93998340
121* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.93785362

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.19033855
2MP0003300_gastrointestinal_ulcer3.37619607
3MP0003705_abnormal_hypodermis_morpholog3.28118826
4MP0003303_peritoneal_inflammation3.05710876
5MP0010234_abnormal_vibrissa_follicle3.01322701
6MP0005451_abnormal_body_composition2.87552069
7MP0008260_abnormal_autophagy2.78330337
8MP0005076_abnormal_cell_differentiation2.77950304
9MP0004185_abnormal_adipocyte_glucose2.65573822
10MP0008057_abnormal_DNA_replication2.44651018
11MP0010352_gastrointestinal_tract_polyps2.36399401
12MP0002166_altered_tumor_susceptibility2.17290972
13MP0005409_darkened_coat_color2.15839161
14MP0003566_abnormal_cell_adhesion2.05444706
15MP0003763_abnormal_thymus_physiology2.02518789
16MP0009278_abnormal_bone_marrow1.99119350
17MP0000733_abnormal_muscle_development1.99102290
18MP0010678_abnormal_skin_adnexa1.96636290
19MP0010307_abnormal_tumor_latency1.92200518
20MP0003724_increased_susceptibility_to1.91712098
21MP0008438_abnormal_cutaneous_collagen1.83195426
22MP0003091_abnormal_cell_migration1.67606581
23MP0004381_abnormal_hair_follicle1.63836328
24MP0000383_abnormal_hair_follicle1.63088345
25MP0002006_tumorigenesis1.62938944
26MP0005275_abnormal_skin_tensile1.62396190
27MP0003221_abnormal_cardiomyocyte_apopto1.58663886
28MP0003656_abnormal_erythrocyte_physiolo1.56336420
29MP0004947_skin_inflammation1.53673912
30MP0000015_abnormal_ear_pigmentation1.51412252
31MP0002009_preneoplasia1.49989593
32MP0003453_abnormal_keratinocyte_physiol1.49827723
33MP0002877_abnormal_melanocyte_morpholog1.46710103
34MP0004808_abnormal_hematopoietic_stem1.44848071
35MP0003828_pulmonary_edema1.38419120
36MP0002396_abnormal_hematopoietic_system1.35755632
37MP0005058_abnormal_lysosome_morphology1.32342253
38MP0001851_eye_inflammation1.31050728
39MP0003436_decreased_susceptibility_to1.30568796
40MP0000858_altered_metastatic_potential1.30000083
41MP0004510_myositis1.27108249
42MP0005666_abnormal_adipose_tissue1.26272110
43MP0003448_altered_tumor_morphology1.22855652
44MP0004130_abnormal_muscle_cell1.21931281
45MP0000465_gastrointestinal_hemorrhage1.21174692
46MP0004883_abnormal_blood_vessel1.20439922
47MP0005025_abnormal_response_to1.18825418
48MP0009053_abnormal_anal_canal1.18743815
49MP0001800_abnormal_humoral_immune1.18737930
50MP0005397_hematopoietic_system_phenotyp1.18707401
51MP0001545_abnormal_hematopoietic_system1.18707401
52MP0000767_abnormal_smooth_muscle1.17304977
53MP0002060_abnormal_skin_morphology1.16928938
54MP0004233_abnormal_muscle_weight1.16900984
55MP0003045_fibrosis1.13083480
56MP0000377_abnormal_hair_follicle1.12752148
57MP0003567_abnormal_fetal_cardiomyocyte1.11498136
58MP0010630_abnormal_cardiac_muscle1.11356791
59MP0001958_emphysema1.10828828
60MP0005621_abnormal_cell_physiology1.10506054
61MP0002452_abnormal_antigen_presenting1.09959196
62MP0005248_abnormal_Harderian_gland1.09164136
63MP0003183_abnormal_peptide_metabolism1.08567241
64MP0000427_abnormal_hair_cycle1.07729940
65MP0005464_abnormal_platelet_physiology1.07595743
66MP0005083_abnormal_biliary_tract1.07478988
67MP0003191_abnormal_cellular_cholesterol1.06593954
68MP0002925_abnormal_cardiovascular_devel1.05842321
69MP0001790_abnormal_immune_system1.05683146
70MP0005387_immune_system_phenotype1.05683146
71MP0002796_impaired_skin_barrier1.05524449
72MP0001915_intracranial_hemorrhage1.05330182
73MP0005023_abnormal_wound_healing1.04105447
74MP0005164_abnormal_response_to1.04083142
75MP0000371_diluted_coat_color1.02748982
76MP0010368_abnormal_lymphatic_system1.02679039
77MP0002086_abnormal_extraembryonic_tissu1.00551770
78MP0003172_abnormal_lysosome_physiology0.99760506
79MP0002419_abnormal_innate_immunity0.99594282
80MP0001835_abnormal_antigen_presentation0.99188463
81MP0001216_abnormal_epidermal_layer0.98559440
82MP0001849_ear_inflammation0.98366146
83MP0005375_adipose_tissue_phenotype0.96807405
84MP0002398_abnormal_bone_marrow0.96053633
85MP0004197_abnormal_fetal_growth/weight/0.95448580
86MP0005257_abnormal_intraocular_pressure0.94139535
87MP0000647_abnormal_sebaceous_gland0.92136785
88MP0001879_abnormal_lymphatic_vessel0.91813909
89MP0002088_abnormal_embryonic_growth/wei0.91332362
90MP0005000_abnormal_immune_tolerance0.90885764
91MP0005501_abnormal_skin_physiology0.90015349
92MP0003984_embryonic_growth_retardation0.89610690
93MP0002429_abnormal_blood_cell0.89145928
94MP0001784_abnormal_fluid_regulation0.89106471
95MP0002420_abnormal_adaptive_immunity0.88996916
96MP0010155_abnormal_intestine_physiology0.88657188
97MP0001533_abnormal_skeleton_physiology0.88080624
98MP0001819_abnormal_immune_cell0.87855133
99MP0002098_abnormal_vibrissa_morphology0.87527551
100MP0002998_abnormal_bone_remodeling0.87029886
101MP0009384_cardiac_valve_regurgitation0.86299570
102MP0002405_respiratory_system_inflammati0.85675164
103MP0009115_abnormal_fat_cell0.85022473
104MP0003690_abnormal_glial_cell0.83285815
105MP0004484_altered_response_of0.83111098
106MP0002723_abnormal_immune_serum0.83063626
107MP0009785_altered_susceptibility_to0.81027435
108MP0000703_abnormal_thymus_morphology0.79903000
109MP0008004_abnormal_stomach_pH0.79704340
110MP0001853_heart_inflammation0.79386169
111MP0002332_abnormal_exercise_endurance0.79296748
112MP0004087_abnormal_muscle_fiber0.79035549
113MP0009931_abnormal_skin_appearance0.78636084
114MP0006138_congestive_heart_failure0.78440904
115MP0006082_CNS_inflammation0.78352591
116MP0001672_abnormal_embryogenesis/_devel0.78133866
117MP0005380_embryogenesis_phenotype0.78133866
118MP0001614_abnormal_blood_vessel0.77959977
119MP0000685_abnormal_immune_system0.77916398
120MP0006054_spinal_hemorrhage0.77327510
121MP0000266_abnormal_heart_morphology0.77074945
122MP0002128_abnormal_blood_circulation0.76570435
123MP0005174_abnormal_tail_pigmentation0.76206138
124MP0002933_joint_inflammation0.75392247
125MP0004264_abnormal_extraembryonic_tissu0.74930283
126MP0005310_abnormal_salivary_gland0.74676205
127MP0009703_decreased_birth_body0.73860984
128MP0000689_abnormal_spleen_morphology0.73333418
129MP0000716_abnormal_immune_system0.73049589
130MP0002722_abnormal_immune_system0.72645319
131MP0004084_abnormal_cardiac_muscle0.71439305

Predicted human phenotypes

RankGene SetZ-score
1Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.70919188
2Hematochezia (HP:0002573)3.21441937
3Abnormality of the fingertips (HP:0001211)3.16400511
4Arterial tortuosity (HP:0005116)2.98833420
5Macroorchidism (HP:0000053)2.97720633
6Aortic aneurysm (HP:0004942)2.94289279
7Cerebral aneurysm (HP:0004944)2.92017010
8Mitral valve prolapse (HP:0001634)2.83178611
9Eczematoid dermatitis (HP:0000976)2.76000338
10Osteolytic defects of the hand bones (HP:0009699)2.73960470
11Osteolytic defects of the phalanges of the hand (HP:0009771)2.73960470
12Disinhibition (HP:0000734)2.73680996
13T lymphocytopenia (HP:0005403)2.62533139
14Asymmetry of the thorax (HP:0001555)2.62266336
15Myocardial infarction (HP:0001658)2.60287175
16Subacute progressive viral hepatitis (HP:0006572)2.59300528
17Vascular tortuosity (HP:0004948)2.58947294
18Slow saccadic eye movements (HP:0000514)2.57570606
19Aortic dissection (HP:0002647)2.55583162
20Hypochromic microcytic anemia (HP:0004840)2.54732663
21Gastrointestinal infarctions (HP:0005244)2.53431459
22Gingivitis (HP:0000230)2.48477066
23Spinal cord lesions (HP:0100561)2.42165261
24Syringomyelia (HP:0003396)2.42165261
25Absent frontal sinuses (HP:0002688)2.39495033
26Disproportionate tall stature (HP:0001519)2.37591986
27Transitional cell carcinoma of the bladder (HP:0006740)2.32059499
28Abnormality of T cell number (HP:0011839)2.31853339
29Volvulus (HP:0002580)2.31290054
30Narrow palate (HP:0000189)2.30453733
31Polycythemia (HP:0001901)2.28375853
32Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.27261759
33Short 4th metacarpal (HP:0010044)2.27261759
34Shallow orbits (HP:0000586)2.27048848
35Spondylolisthesis (HP:0003302)2.23328011
36Abnormality of macrophages (HP:0004311)2.22777290
37Bladder carcinoma (HP:0002862)2.21896533
38Bladder neoplasm (HP:0009725)2.21896533
39Prolonged bleeding time (HP:0003010)2.16328719
40Thick nail (HP:0001805)2.15725884
41Dysmetric saccades (HP:0000641)2.14732534
42Heterotopia (HP:0002282)2.13946370
43Genu recurvatum (HP:0002816)2.13931427
44Pustule (HP:0200039)2.10323035
45Rectal prolapse (HP:0002035)2.08925128
46Recurrent bacterial skin infections (HP:0005406)2.06826276
47Epistaxis (HP:0000421)2.06241390
48Persistence of primary teeth (HP:0006335)2.04980510
49Increased density of long bones (HP:0006392)1.99610658
50Recurrent skin infections (HP:0001581)1.98120200
51Recurrent abscess formation (HP:0002722)1.97974381
52Hypoplastic ischia (HP:0003175)1.96459769
53Enlarged penis (HP:0000040)1.95650467
54Conjunctival telangiectasia (HP:0000524)1.95634711
55Aneurysm (HP:0002617)1.95223887
56Truncal obesity (HP:0001956)1.94965016
57Microcytic anemia (HP:0001935)1.93435061
58Dislocated radial head (HP:0003083)1.91667408
59Hyporeflexia of lower limbs (HP:0002600)1.91608352
60Periodontitis (HP:0000704)1.90575453
61Dilatation of the ascending aorta (HP:0005111)1.89921269
62Poikilocytosis (HP:0004447)1.89425103
63Long eyelashes (HP:0000527)1.88860635
64Recurrent gram-negative bacterial infections (HP:0005420)1.88858158
65Premature rupture of membranes (HP:0001788)1.88602906
66Abnormality of the 4th metacarpal (HP:0010012)1.87977494
67Ankyloglossia (HP:0010296)1.87638773
68Germ cell neoplasia (HP:0100728)1.87500690
69Fatigue (HP:0012378)1.87218559
70Overgrowth (HP:0001548)1.86832887
71Abnormality of the vasculature of the conjunctiva (HP:0008054)1.86416844
72Orchitis (HP:0100796)1.83484737
73Leiomyosarcoma (HP:0100243)1.83028482
74Uterine leiomyosarcoma (HP:0002891)1.83028482
75Subaortic stenosis (HP:0001682)1.82313720
76Abnormality of the left ventricular outflow tract (HP:0011103)1.82313720
77Flat acetabular roof (HP:0003180)1.81930777
78Myositis (HP:0100614)1.81766067
79Urethral obstruction (HP:0000796)1.81137617
80Exostoses (HP:0100777)1.79703084
81Optic neuritis (HP:0100653)1.77301697
82Retrobulbar optic neuritis (HP:0100654)1.77301697
83Hyperkalemia (HP:0002153)1.77034101
84Bicuspid aortic valve (HP:0001647)1.76493674
85Malignant gastrointestinal tract tumors (HP:0006749)1.76397468
86Gastrointestinal carcinoma (HP:0002672)1.76397468
87Cellulitis (HP:0100658)1.76247301
88Vertebral arch anomaly (HP:0008438)1.75596470
89Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.74240154
90Ulnar bowing (HP:0003031)1.74094289
91Lip pit (HP:0100267)1.73730045
92Cerebral inclusion bodies (HP:0100314)1.73597296
93Recurrent fungal infections (HP:0002841)1.72926973
94Spontaneous hematomas (HP:0007420)1.72266993
95Abnormality of the radial head (HP:0003995)1.72236103
96Difficulty running (HP:0009046)1.71850475
97Increased cerebral lipofuscin (HP:0011813)1.71255092
98Acute myeloid leukemia (HP:0004808)1.71232327
99Papillary thyroid carcinoma (HP:0002895)1.71065418
100Curly hair (HP:0002212)1.70356955
101Viral hepatitis (HP:0006562)1.70115358
102Chest pain (HP:0100749)1.70051744
103Increased variability in muscle fiber diameter (HP:0003557)1.69426470
104Neonatal hypoglycemia (HP:0001998)1.69394280
105Inappropriate behavior (HP:0000719)1.69015399
106Striae distensae (HP:0001065)1.68057760
107Increased IgE level (HP:0003212)1.67554574
108Obstructive sleep apnea (HP:0002870)1.66310769
109Peritonitis (HP:0002586)1.66153736
110Coarse hair (HP:0002208)1.65734798
111Gingival bleeding (HP:0000225)1.65550649
112Deep philtrum (HP:0002002)1.64984246
113Abnormality of the ischium (HP:0003174)1.64408035
114Recurrent cutaneous fungal infections (HP:0011370)1.63141148
115Chronic mucocutaneous candidiasis (HP:0002728)1.63141148
116Recurrent viral infections (HP:0004429)1.62755355
117Abnormality of oral frenula (HP:0000190)1.62582647
118Abnormality of skeletal muscle fiber size (HP:0012084)1.61701278
119Scapular winging (HP:0003691)1.61674633
120Protrusio acetabuli (HP:0003179)1.61534605
121Abnormality of the nasal septum (HP:0000419)1.60267111
122Sparse lateral eyebrow (HP:0005338)1.59955487
123Frequent falls (HP:0002359)1.59640299
124Hypoplasia of the iris (HP:0007676)1.59408269
125Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.58330155
126Gastrointestinal inflammation (HP:0004386)1.58171567
127Resting tremor (HP:0002322)1.57770138
128Cortical dysplasia (HP:0002539)1.57459774
129Limited elbow extension (HP:0001377)1.56885003
130Inflammation of the large intestine (HP:0002037)1.56843339
131Decreased motor nerve conduction velocity (HP:0003431)1.56775443
132Arterial thrombosis (HP:0004420)1.56603756
133Type 1 muscle fiber predominance (HP:0003803)1.55829559
134Colitis (HP:0002583)1.54787696
135Large earlobe (HP:0009748)1.53451469
136Abnormality of the peritoneum (HP:0002585)1.52767701
137Lymphangioma (HP:0100764)1.52674594
138Ankle contracture (HP:0006466)1.50125227
139Cutaneous melanoma (HP:0012056)1.49350382
140Ulnar deviation of the wrist (HP:0003049)1.49148334
141Thick eyebrow (HP:0000574)1.48029782
142Low anterior hairline (HP:0000294)1.47996217
143Abnormality of the frontal sinuses (HP:0002687)1.47638593
144Verrucae (HP:0200043)1.47602036
145Papilloma (HP:0012740)1.47602036
146Abnormal platelet volume (HP:0011876)1.47311965
147Increased mean platelet volume (HP:0011877)1.47237185
148Increased connective tissue (HP:0009025)1.46949448
149Osteomyelitis (HP:0002754)1.46127468

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS13.51866589
2CDK123.27487739
3TRIB33.00527862
4PRPF4B2.83477155
5PKN22.65557004
6CAMK1D2.59189627
7CAMK1G2.55498389
8TTN2.17510903
9EEF2K2.07372919
10STK32.01634059
11DMPK1.90602030
12CDK61.90379834
13STK101.84051915
14TAOK31.78945381
15TGFBR21.77058186
16FGFR31.76865746
17BLK1.72450318
18FRK1.71366887
19EPHB11.70489912
20MAP3K101.69549432
21MAP4K11.54761782
22FGFR21.51055603
23CDK91.49241092
24PTK61.43696220
25SGK21.42524537
26PDGFRB1.40309766
27AKT31.38634423
28TRPM71.38004327
29YES11.37242477
30RIPK11.36482303
31IKBKE1.30104536
32GRK61.26196247
33JAK11.24770138
34BRD41.24487194
35MAP3K11.23829924
36MARK21.22975960
37PIK3CG1.20243062
38KSR11.19349478
39IRAK41.18564741
40MELK1.15572546
41SIK11.14455412
42TAOK11.14218569
43FGFR41.09913866
44ITK1.08130516
45TYK21.07006410
46NEK91.03979349
47EPHA31.03281487
48SIK21.03232438
49BMPR21.02817238
50NUAK11.02614673
51MTOR1.02281262
52ERN11.01078038
53PNCK1.00951344
54RET1.00700278
55PTK2B0.98901122
56JAK30.98863461
57MARK30.98706154
58STK40.98213484
59PDGFRA0.97742222
60LRRK20.94538912
61HCK0.93960928
62SCYL20.90968771
63BMX0.90441186
64STK380.89981153
65NLK0.89295445
66RPS6KA40.89287550
67BTK0.88272482
68MAP3K20.87433301
69NEK20.87017575
70FES0.85852297
71CSK0.83889304
72JAK20.83602130
73MAP3K60.83437443
74CSNK1A1L0.82094922
75SGK30.81519839
76WNK10.78745172
77CDK40.78604880
78CSF1R0.77836261
79ALK0.76785635
80IRAK10.76770478
81KSR20.76278047
82MAP3K90.75864230
83MAP2K30.75366345
84SYK0.74321276
85CDC42BPA0.73286834
86MAP3K70.73267072
87PTK20.72110482
88SGK2230.71747628
89SGK4940.71747628
90LATS20.71650018
91TAOK20.71370865
92FGFR10.70020786
93SIK30.69815074
94EIF2AK10.67648239
95TYRO30.67286792
96CHUK0.66533310
97PIK3CA0.66333960
98RAF10.64870513
99NEK60.64085247
100SMG10.62583982
101MAP3K30.62201111
102HIPK20.61859290
103STK240.60710504
104ABL10.60631538
105EGFR0.60511382
106MAP3K130.59812388
107MAP3K80.59424153
108LCK0.59225445
109FGR0.58245948
110ICK0.57003363
111PRKAA20.56984463
112MAPK70.56018114
113PIM10.55966518
114ZAP700.55632375
115IRAK20.55015211
116CSNK1D0.54708006
117TEC0.54707175
118PAK20.54017263
119PRKD20.51801843
120SGK10.51036058
121PDK10.50819772
122TBK10.50776429
123MAPK120.50631285
124MAPK110.47320446
125DYRK1B0.46803034
126STK110.46659134
127PRKCQ0.46545745
128PRKD10.44213855
129RIPK40.43396142
130MAP3K50.43108162
131CSNK1G10.41925239
132MOS0.40994250
133ERBB20.40307475
134CDC70.40154314
135GSK3A0.39813712
136MAP3K140.39503562
137PDPK10.39182675
138PRKCH0.39156383

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052202.02772560
2Pancreatic cancer_Homo sapiens_hsa052121.84248210
3B cell receptor signaling pathway_Homo sapiens_hsa046621.84190281
4Dorso-ventral axis formation_Homo sapiens_hsa043201.82334616
5Osteoclast differentiation_Homo sapiens_hsa043801.81664970
6Adherens junction_Homo sapiens_hsa045201.68592176
7Renal cell carcinoma_Homo sapiens_hsa052111.62162099
8MicroRNAs in cancer_Homo sapiens_hsa052061.58688060
9Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.55609039
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.53504848
11Small cell lung cancer_Homo sapiens_hsa052221.52627104
12Leishmaniasis_Homo sapiens_hsa051401.52045296
13mTOR signaling pathway_Homo sapiens_hsa041501.50141863
14Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.48114365
15Non-small cell lung cancer_Homo sapiens_hsa052231.45516183
16Toxoplasmosis_Homo sapiens_hsa051451.44837941
17Proteoglycans in cancer_Homo sapiens_hsa052051.43908813
18T cell receptor signaling pathway_Homo sapiens_hsa046601.40958760
19Leukocyte transendothelial migration_Homo sapiens_hsa046701.37240708
20Staphylococcus aureus infection_Homo sapiens_hsa051501.36335997
21Focal adhesion_Homo sapiens_hsa045101.34748513
22Viral myocarditis_Homo sapiens_hsa054161.34730260
23Prostate cancer_Homo sapiens_hsa052151.34511560
24Lysine degradation_Homo sapiens_hsa003101.33642544
25Thyroid cancer_Homo sapiens_hsa052161.33125603
26Glioma_Homo sapiens_hsa052141.30206350
27Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.29596221
28AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.29533693
29Endometrial cancer_Homo sapiens_hsa052131.27589001
30Hepatitis B_Homo sapiens_hsa051611.20721062
31Platelet activation_Homo sapiens_hsa046111.20511124
32Inositol phosphate metabolism_Homo sapiens_hsa005621.19588087
33Insulin resistance_Homo sapiens_hsa049311.18196855
34FoxO signaling pathway_Homo sapiens_hsa040681.17359371
35NF-kappa B signaling pathway_Homo sapiens_hsa040641.17165498
36Toll-like receptor signaling pathway_Homo sapiens_hsa046201.16348653
37Acute myeloid leukemia_Homo sapiens_hsa052211.14856221
38Colorectal cancer_Homo sapiens_hsa052101.14566084
39TGF-beta signaling pathway_Homo sapiens_hsa043501.13728343
40Regulation of actin cytoskeleton_Homo sapiens_hsa048101.10672797
41VEGF signaling pathway_Homo sapiens_hsa043701.09644791
42Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.06786419
43Prolactin signaling pathway_Homo sapiens_hsa049171.06210437
44ECM-receptor interaction_Homo sapiens_hsa045121.05683354
45Neurotrophin signaling pathway_Homo sapiens_hsa047221.05316990
46Amoebiasis_Homo sapiens_hsa051461.02333050
47Thyroid hormone signaling pathway_Homo sapiens_hsa049191.00766044
48Measles_Homo sapiens_hsa051621.00599936
49Chemokine signaling pathway_Homo sapiens_hsa040620.99329255
50Tuberculosis_Homo sapiens_hsa051520.99184186
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99052511
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96159741
53Malaria_Homo sapiens_hsa051440.95658287
54NOD-like receptor signaling pathway_Homo sapiens_hsa046210.95613583
55RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.94982112
56Caffeine metabolism_Homo sapiens_hsa002320.93204468
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.92997678
58Longevity regulating pathway - mammal_Homo sapiens_hsa042110.91620806
59TNF signaling pathway_Homo sapiens_hsa046680.91430274
60Other glycan degradation_Homo sapiens_hsa005110.89872020
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.89253287
62Choline metabolism in cancer_Homo sapiens_hsa052310.88165244
63Type II diabetes mellitus_Homo sapiens_hsa049300.87530175
64Apoptosis_Homo sapiens_hsa042100.86212446
65Jak-STAT signaling pathway_Homo sapiens_hsa046300.84757773
66Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.83247349
67Long-term potentiation_Homo sapiens_hsa047200.83076125
68Endocytosis_Homo sapiens_hsa041440.82961772
69Hematopoietic cell lineage_Homo sapiens_hsa046400.82770084
70Influenza A_Homo sapiens_hsa051640.82264477
71Notch signaling pathway_Homo sapiens_hsa043300.82037769
72ErbB signaling pathway_Homo sapiens_hsa040120.81847326
73AMPK signaling pathway_Homo sapiens_hsa041520.81289023
74Nitrogen metabolism_Homo sapiens_hsa009100.81056959
75HTLV-I infection_Homo sapiens_hsa051660.80962505
76Shigellosis_Homo sapiens_hsa051310.80714604
77Legionellosis_Homo sapiens_hsa051340.79367072
78Glycosaminoglycan degradation_Homo sapiens_hsa005310.78722139
79Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78543158
80Bladder cancer_Homo sapiens_hsa052190.78417956
81Hepatitis C_Homo sapiens_hsa051600.78357252
82Herpes simplex infection_Homo sapiens_hsa051680.75882191
83Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.75834042
84Adipocytokine signaling pathway_Homo sapiens_hsa049200.75718823
85Melanoma_Homo sapiens_hsa052180.75297353
86MAPK signaling pathway_Homo sapiens_hsa040100.74876976
87Viral carcinogenesis_Homo sapiens_hsa052030.74840171
88Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.74156957
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.72181113
90Estrogen signaling pathway_Homo sapiens_hsa049150.72051484
91Salmonella infection_Homo sapiens_hsa051320.71570489
92Hippo signaling pathway_Homo sapiens_hsa043900.70781729
93Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.70732288
94Pathways in cancer_Homo sapiens_hsa052000.70083505
95Pertussis_Homo sapiens_hsa051330.69871160
96Rap1 signaling pathway_Homo sapiens_hsa040150.69845105
97Insulin signaling pathway_Homo sapiens_hsa049100.69404092
98Phosphatidylinositol signaling system_Homo sapiens_hsa040700.69146393
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68426869
100Lysosome_Homo sapiens_hsa041420.68367127
101Antigen processing and presentation_Homo sapiens_hsa046120.67724241
102Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.67433282
103Primary immunodeficiency_Homo sapiens_hsa053400.66422791
104Dilated cardiomyopathy_Homo sapiens_hsa054140.65999417
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.65021385
106HIF-1 signaling pathway_Homo sapiens_hsa040660.64598145
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.63459373
108Circadian rhythm_Homo sapiens_hsa047100.60204208
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59193430
110GnRH signaling pathway_Homo sapiens_hsa049120.57114213
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56449995
112Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52044839
113Ras signaling pathway_Homo sapiens_hsa040140.48917884
114Phagosome_Homo sapiens_hsa041450.48434676

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