Rank | Gene Set | Z-score |
---|---|---|
1 | nucleobase biosynthetic process (GO:0046112) | 4.76953249 |
2 | purine nucleobase biosynthetic process (GO:0009113) | 4.67937158 |
3 | mitotic metaphase plate congression (GO:0007080) | 4.67779072 |
4 | protein localization to kinetochore (GO:0034501) | 4.61288955 |
5 | nuclear pore organization (GO:0006999) | 4.61122533 |
6 | nuclear pore complex assembly (GO:0051292) | 4.48234288 |
7 | ribosome assembly (GO:0042255) | 4.40523149 |
8 | DNA replication initiation (GO:0006270) | 4.24325506 |
9 | mitotic nuclear envelope disassembly (GO:0007077) | 4.20533119 |
10 | establishment of integrated proviral latency (GO:0075713) | 4.19300380 |
11 | maturation of SSU-rRNA (GO:0030490) | 4.18855623 |
12 | formation of translation preinitiation complex (GO:0001731) | 4.18632668 |
13 | DNA replication checkpoint (GO:0000076) | 4.15362446 |
14 | IMP biosynthetic process (GO:0006188) | 4.14679263 |
15 | ribosome biogenesis (GO:0042254) | 4.14116594 |
16 | DNA unwinding involved in DNA replication (GO:0006268) | 4.04668028 |
17 | metaphase plate congression (GO:0051310) | 4.02758470 |
18 | regulation of spindle organization (GO:0090224) | 4.01531941 |
19 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.01027140 |
20 | membrane disassembly (GO:0030397) | 3.90316650 |
21 | nuclear envelope disassembly (GO:0051081) | 3.90316650 |
22 | protein localization to chromosome, centromeric region (GO:0071459) | 3.87679592 |
23 | DNA strand elongation (GO:0022616) | 3.85129510 |
24 | proteasome assembly (GO:0043248) | 3.81168037 |
25 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.80533572 |
26 | non-recombinational repair (GO:0000726) | 3.79280831 |
27 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.79280831 |
28 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.73872370 |
29 | CENP-A containing nucleosome assembly (GO:0034080) | 3.72838671 |
30 | regulation of centriole replication (GO:0046599) | 3.72397495 |
31 | chromatin remodeling at centromere (GO:0031055) | 3.71003903 |
32 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.70911730 |
33 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.70911730 |
34 | ribosomal large subunit biogenesis (GO:0042273) | 3.67815696 |
35 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.66554027 |
36 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.65981919 |
37 | IMP metabolic process (GO:0046040) | 3.62959178 |
38 | pore complex assembly (GO:0046931) | 3.55026494 |
39 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.53167276 |
40 | DNA replication-independent nucleosome organization (GO:0034724) | 3.51183128 |
41 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.51183128 |
42 | ribosomal small subunit assembly (GO:0000028) | 3.50045157 |
43 | establishment of chromosome localization (GO:0051303) | 3.49474597 |
44 | kinetochore organization (GO:0051383) | 3.45269598 |
45 | rRNA processing (GO:0006364) | 3.45166934 |
46 | mitotic chromosome condensation (GO:0007076) | 3.44845786 |
47 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.42125117 |
48 | mitochondrial RNA metabolic process (GO:0000959) | 3.41746859 |
49 | mitotic sister chromatid segregation (GO:0000070) | 3.40083163 |
50 | transcription from mitochondrial promoter (GO:0006390) | 3.39470689 |
51 | regulation of mitotic spindle organization (GO:0060236) | 3.39195063 |
52 | telomere maintenance via recombination (GO:0000722) | 3.38957386 |
53 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.37698883 |
54 | rRNA metabolic process (GO:0016072) | 3.35306356 |
55 | positive regulation of chromosome segregation (GO:0051984) | 3.35210953 |
56 | DNA double-strand break processing (GO:0000729) | 3.34991351 |
57 | rRNA methylation (GO:0031167) | 3.33918275 |
58 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.33814754 |
59 | mitotic recombination (GO:0006312) | 3.32427360 |
60 | regulation of translational fidelity (GO:0006450) | 3.29053177 |
61 | spindle checkpoint (GO:0031577) | 3.26925501 |
62 | viral mRNA export from host cell nucleus (GO:0046784) | 3.26030962 |
63 | tRNA aminoacylation for protein translation (GO:0006418) | 3.25744104 |
64 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.24488357 |
65 | amino acid activation (GO:0043038) | 3.23999526 |
66 | tRNA aminoacylation (GO:0043039) | 3.23999526 |
67 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.22371585 |
68 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.21888643 |
69 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.21888643 |
70 | histone exchange (GO:0043486) | 3.20947339 |
71 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.20879121 |
72 | telomere maintenance via telomere lengthening (GO:0010833) | 3.19920090 |
73 | spliceosomal snRNP assembly (GO:0000387) | 3.19673788 |
74 | folic acid metabolic process (GO:0046655) | 3.19134916 |
75 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.17049433 |
76 | isotype switching (GO:0045190) | 3.17049433 |
77 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.17049433 |
78 | sister chromatid segregation (GO:0000819) | 3.15628200 |
79 | replication fork processing (GO:0031297) | 3.13249142 |
80 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.13210184 |
81 | negative regulation of mRNA processing (GO:0050686) | 3.12980914 |
82 | DNA duplex unwinding (GO:0032508) | 3.12323943 |
83 | DNA geometric change (GO:0032392) | 3.12254146 |
84 | mitotic spindle checkpoint (GO:0071174) | 3.11680604 |
85 | maturation of 5.8S rRNA (GO:0000460) | 3.11236780 |
86 | negative regulation of chromosome segregation (GO:0051985) | 3.11066623 |
87 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.10794088 |
88 | negative regulation of ligase activity (GO:0051352) | 3.10794088 |
89 | regulation of helicase activity (GO:0051095) | 3.09301221 |
90 | regulation of chromosome segregation (GO:0051983) | 3.08849908 |
91 | nuclear envelope organization (GO:0006998) | 3.08819972 |
92 | spindle assembly checkpoint (GO:0071173) | 3.08692188 |
93 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.08434828 |
94 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.08434828 |
95 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.08434828 |
96 | negative regulation of sister chromatid segregation (GO:0033046) | 3.08434828 |
97 | translational initiation (GO:0006413) | 3.08024426 |
98 | kinetochore assembly (GO:0051382) | 3.07476039 |
99 | establishment of viral latency (GO:0019043) | 3.06537248 |
100 | rRNA modification (GO:0000154) | 3.05840084 |
101 | mitotic spindle assembly checkpoint (GO:0007094) | 3.05593840 |
102 | regulation of centrosome cycle (GO:0046605) | 3.02745211 |
103 | protein K6-linked ubiquitination (GO:0085020) | 3.02226693 |
104 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.02207791 |
105 | protein localization to chromosome (GO:0034502) | 3.01950678 |
106 | translational termination (GO:0006415) | 2.99655400 |
107 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.99184643 |
108 | chromatin assembly or disassembly (GO:0006333) | 2.98659754 |
109 | pseudouridine synthesis (GO:0001522) | 2.98477266 |
110 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.97872348 |
111 | ribosomal small subunit biogenesis (GO:0042274) | 2.97443349 |
112 | termination of RNA polymerase I transcription (GO:0006363) | 2.96971407 |
113 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.95890380 |
114 | mitotic sister chromatid cohesion (GO:0007064) | 2.95600225 |
115 | meiotic chromosome segregation (GO:0045132) | 2.95214637 |
116 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.95201444 |
117 | viral transcription (GO:0019083) | 2.94671236 |
118 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.93331520 |
119 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.93331520 |
120 | regulation of translational termination (GO:0006449) | 2.91620979 |
121 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.90483691 |
122 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.87845462 |
123 | RNA splicing, via transesterification reactions (GO:0000375) | 2.85238007 |
124 | mRNA splicing, via spliceosome (GO:0000398) | 2.82942970 |
125 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.82942970 |
126 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.82583692 |
127 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.82583692 |
128 | regulation of sister chromatid segregation (GO:0033045) | 2.82583692 |
129 | DNA deamination (GO:0045006) | 2.79178312 |
130 | ATP-dependent chromatin remodeling (GO:0043044) | 2.78996542 |
131 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.78314250 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.87655996 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.34452183 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.24080964 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.80225916 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.27956009 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.13814525 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.11879556 |
8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.86872479 |
9 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.86469866 |
10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.78861742 |
11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.65762469 |
12 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.64297348 |
13 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.63870335 |
14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.63245426 |
15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.56082807 |
16 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.45198383 |
17 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.40787718 |
18 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.32844064 |
19 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.24818414 |
20 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.23881544 |
21 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.22408950 |
22 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.16025732 |
23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.14459243 |
24 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.13033811 |
25 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.05154803 |
26 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.98048038 |
27 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.97827669 |
28 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.97200685 |
29 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.92745163 |
30 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.87310064 |
31 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.84004091 |
32 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.83701215 |
33 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.76570707 |
34 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.74551062 |
35 | * PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.74117173 |
36 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.73475705 |
37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72480602 |
38 | MYC_22102868_ChIP-Seq_BL_Human | 1.71498736 |
39 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.68416282 |
40 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.64115736 |
41 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.63508284 |
42 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.61519619 |
43 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.58180298 |
44 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.57937939 |
45 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.56971315 |
46 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.55288965 |
47 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.50885934 |
48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.50596360 |
49 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.46406368 |
50 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41856689 |
51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.41686409 |
52 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.41575770 |
53 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.35427675 |
54 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.32937527 |
55 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.32313369 |
56 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.29964856 |
57 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.29963551 |
58 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.29378199 |
59 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.29210662 |
60 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.28389567 |
61 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.28368472 |
62 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.28191213 |
63 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26555992 |
64 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.25794001 |
65 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.25256069 |
66 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.23237314 |
67 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.19990904 |
68 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.17221173 |
69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16578411 |
70 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.15558153 |
71 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.13636079 |
72 | EWS_26573619_Chip-Seq_HEK293_Human | 1.13230581 |
73 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.12987794 |
74 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10632186 |
75 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.10513463 |
76 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.08743377 |
77 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.08730959 |
78 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.08541143 |
79 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.08421998 |
80 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.07698260 |
81 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.04226242 |
82 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.03125597 |
83 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.01208697 |
84 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01028708 |
85 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.99429587 |
86 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.98900081 |
87 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.97656737 |
88 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.96995748 |
89 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.96750231 |
90 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95395987 |
91 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.94901845 |
92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93586692 |
93 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.91780625 |
94 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.91504787 |
95 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.91504787 |
96 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.91504787 |
97 | FUS_26573619_Chip-Seq_HEK293_Human | 0.91221695 |
98 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.89936584 |
99 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.89503950 |
100 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.88551228 |
101 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.87725487 |
102 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.87165221 |
103 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.87030851 |
104 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.86870533 |
105 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.86474985 |
106 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.84616569 |
107 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.83094682 |
108 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.81464821 |
109 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.81408695 |
110 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.79825701 |
111 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.78345370 |
112 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.77317712 |
113 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.76984271 |
114 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.75863785 |
115 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.75436887 |
116 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.72167643 |
117 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.69885767 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.48833658 |
2 | MP0010094_abnormal_chromosome_stability | 4.49050239 |
3 | MP0003111_abnormal_nucleus_morphology | 4.40799827 |
4 | MP0004957_abnormal_blastocyst_morpholog | 4.28266647 |
5 | MP0008057_abnormal_DNA_replication | 4.18581794 |
6 | MP0003077_abnormal_cell_cycle | 4.00859313 |
7 | MP0008058_abnormal_DNA_repair | 3.15505341 |
8 | MP0008007_abnormal_cellular_replicative | 2.99963160 |
9 | MP0002396_abnormal_hematopoietic_system | 2.73073351 |
10 | MP0003123_paternal_imprinting | 2.48058252 |
11 | MP0008932_abnormal_embryonic_tissue | 2.47440530 |
12 | MP0001730_embryonic_growth_arrest | 2.43372625 |
13 | MP0009697_abnormal_copulation | 2.36521979 |
14 | MP0000350_abnormal_cell_proliferation | 2.35164049 |
15 | MP0010352_gastrointestinal_tract_polyps | 2.33162426 |
16 | MP0010307_abnormal_tumor_latency | 2.24961454 |
17 | MP0003786_premature_aging | 2.09562977 |
18 | MP0001672_abnormal_embryogenesis/_devel | 1.90816450 |
19 | MP0005380_embryogenesis_phenotype | 1.90816450 |
20 | MP0008877_abnormal_DNA_methylation | 1.88491268 |
21 | MP0003718_maternal_effect | 1.85256169 |
22 | MP0001697_abnormal_embryo_size | 1.75654895 |
23 | MP0003984_embryonic_growth_retardation | 1.73348021 |
24 | MP0002088_abnormal_embryonic_growth/wei | 1.69324411 |
25 | MP0002080_prenatal_lethality | 1.61690663 |
26 | MP0000490_abnormal_crypts_of | 1.60303702 |
27 | MP0004808_abnormal_hematopoietic_stem | 1.60218412 |
28 | MP0009333_abnormal_splenocyte_physiolog | 1.58783344 |
29 | MP0002085_abnormal_embryonic_tissue | 1.54211285 |
30 | MP0002084_abnormal_developmental_patter | 1.52136594 |
31 | MP0002086_abnormal_extraembryonic_tissu | 1.50503279 |
32 | MP0004197_abnormal_fetal_growth/weight/ | 1.45342096 |
33 | MP0006035_abnormal_mitochondrial_morpho | 1.43005142 |
34 | MP0000313_abnormal_cell_death | 1.39874823 |
35 | MP0002019_abnormal_tumor_incidence | 1.38077456 |
36 | MP0003567_abnormal_fetal_cardiomyocyte | 1.36135532 |
37 | MP0003763_abnormal_thymus_physiology | 1.29901645 |
38 | MP0005076_abnormal_cell_differentiation | 1.26246138 |
39 | MP0000372_irregular_coat_pigmentation | 1.26076390 |
40 | MP0001293_anophthalmia | 1.23694495 |
41 | MP0003121_genomic_imprinting | 1.22276313 |
42 | MP0005397_hematopoietic_system_phenotyp | 1.18736292 |
43 | MP0001545_abnormal_hematopoietic_system | 1.18736292 |
44 | MP0002210_abnormal_sex_determination | 1.10792413 |
45 | MP0001661_extended_life_span | 1.10102160 |
46 | MP0000703_abnormal_thymus_morphology | 1.09467218 |
47 | MP0002398_abnormal_bone_marrow | 1.07538590 |
48 | MP0003941_abnormal_skin_development | 1.06218329 |
49 | MP0003806_abnormal_nucleotide_metabolis | 1.05567566 |
50 | MP0010234_abnormal_vibrissa_follicle | 1.05202580 |
51 | MP0003890_abnormal_embryonic-extraembry | 1.04402002 |
52 | MP0006036_abnormal_mitochondrial_physio | 1.03745640 |
53 | MP0002877_abnormal_melanocyte_morpholog | 1.02886007 |
54 | MP0002697_abnormal_eye_size | 1.02748252 |
55 | MP0002009_preneoplasia | 1.02099720 |
56 | MP0010030_abnormal_orbit_morphology | 1.00816643 |
57 | MP0002722_abnormal_immune_system | 1.00391406 |
58 | MP0001145_abnormal_male_reproductive | 0.98292614 |
59 | MP0000689_abnormal_spleen_morphology | 0.97763671 |
60 | MP0004185_abnormal_adipocyte_glucose | 0.96259065 |
61 | MP0009672_abnormal_birth_weight | 0.94369851 |
62 | MP0003950_abnormal_plasma_membrane | 0.87570760 |
63 | MP0005621_abnormal_cell_physiology | 0.85925643 |
64 | MP0006072_abnormal_retinal_apoptosis | 0.85052461 |
65 | MP0003937_abnormal_limbs/digits/tail_de | 0.84583174 |
66 | MP0003221_abnormal_cardiomyocyte_apopto | 0.84356472 |
67 | MP0005384_cellular_phenotype | 0.84206517 |
68 | MP0000653_abnormal_sex_gland | 0.84087881 |
69 | MP0000647_abnormal_sebaceous_gland | 0.83927858 |
70 | MP0003943_abnormal_hepatobiliary_system | 0.83644742 |
71 | MP0005023_abnormal_wound_healing | 0.82601074 |
72 | MP0005501_abnormal_skin_physiology | 0.81934869 |
73 | MP0005408_hypopigmentation | 0.81682439 |
74 | MP0001929_abnormal_gametogenesis | 0.81390055 |
75 | MP0002429_abnormal_blood_cell | 0.80847331 |
76 | MP0002166_altered_tumor_susceptibility | 0.80166302 |
77 | MP0004233_abnormal_muscle_weight | 0.80057331 |
78 | MP0009053_abnormal_anal_canal | 0.79633084 |
79 | MP0000428_abnormal_craniofacial_morphol | 0.78889547 |
80 | MP0002254_reproductive_system_inflammat | 0.78635274 |
81 | MP0002102_abnormal_ear_morphology | 0.77959427 |
82 | MP0001915_intracranial_hemorrhage | 0.77219576 |
83 | MP0002111_abnormal_tail_morphology | 0.76972670 |
84 | MP0001119_abnormal_female_reproductive | 0.76361205 |
85 | MP0002796_impaired_skin_barrier | 0.76259746 |
86 | MP0000358_abnormal_cell_content/ | 0.75569636 |
87 | MP0005395_other_phenotype | 0.74887888 |
88 | MP0000858_altered_metastatic_potential | 0.74868245 |
89 | MP0003315_abnormal_perineum_morphology | 0.74867028 |
90 | MP0002233_abnormal_nose_morphology | 0.74598339 |
91 | MP0009703_decreased_birth_body | 0.73965674 |
92 | MP0008995_early_reproductive_senescence | 0.73908476 |
93 | MP0002160_abnormal_reproductive_system | 0.73169535 |
94 | MP0010678_abnormal_skin_adnexa | 0.72030759 |
95 | MP0002092_abnormal_eye_morphology | 0.71878004 |
96 | MP0002163_abnormal_gland_morphology | 0.71669931 |
97 | MP0000716_abnormal_immune_system | 0.71579853 |
98 | MP0005220_abnormal_exocrine_pancreas | 0.70168144 |
99 | MP0005389_reproductive_system_phenotype | 0.69612566 |
100 | MP0005075_abnormal_melanosome_morpholog | 0.68841602 |
101 | MP0003119_abnormal_digestive_system | 0.68624329 |
102 | MP0004264_abnormal_extraembryonic_tissu | 0.68266676 |
103 | MP0003699_abnormal_female_reproductive | 0.67989406 |
104 | MP0001881_abnormal_mammary_gland | 0.67708440 |
105 | MP0003705_abnormal_hypodermis_morpholog | 0.65845488 |
106 | MP0006292_abnormal_olfactory_placode | 0.65838175 |
107 | MP0000733_abnormal_muscle_development | 0.65666425 |
108 | MP0001849_ear_inflammation | 0.64990322 |
109 | MP0002132_abnormal_respiratory_system | 0.64740405 |
110 | MP0001727_abnormal_embryo_implantation | 0.64305620 |
111 | MP0003566_abnormal_cell_adhesion | 0.64105645 |
112 | MP0000537_abnormal_urethra_morphology | 0.63621833 |
113 | MP0001800_abnormal_humoral_immune | 0.63036736 |
114 | MP0001286_abnormal_eye_development | 0.62101722 |
115 | MP0000432_abnormal_head_morphology | 0.61980679 |
116 | MP0009278_abnormal_bone_marrow | 0.61534451 |
117 | MP0000477_abnormal_intestine_morphology | 0.59568990 |
118 | MP0000750_abnormal_muscle_regeneration | 0.59434844 |
119 | MP0000627_abnormal_mammary_gland | 0.58326236 |
120 | MP0003448_altered_tumor_morphology | 0.58126505 |
121 | MP0001853_heart_inflammation | 0.57595260 |
122 | MP0005671_abnormal_response_to | 0.55377219 |
123 | MP0008789_abnormal_olfactory_epithelium | 0.54212124 |
124 | MP0002006_tumorigenesis | 0.53972654 |
125 | MP0003755_abnormal_palate_morphology | 0.53262082 |
126 | MP0005379_endocrine/exocrine_gland_phen | 0.53097573 |
127 | MP0003136_yellow_coat_color | 0.53023925 |
128 | MP0002452_abnormal_antigen_presenting | 0.52903857 |
129 | MP0002095_abnormal_skin_pigmentation | 0.52643233 |
130 | MP0002938_white_spotting | 0.52606269 |
131 | MP0002420_abnormal_adaptive_immunity | 0.52324137 |
132 | MP0003186_abnormal_redox_activity | 0.51634350 |
133 | MP0001819_abnormal_immune_cell | 0.51136539 |
134 | MP0000465_gastrointestinal_hemorrhage | 0.51017365 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.23636670 |
2 | Breast hypoplasia (HP:0003187) | 3.98229377 |
3 | Chromsome breakage (HP:0040012) | 3.68298184 |
4 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.44156940 |
5 | Reticulocytopenia (HP:0001896) | 3.40086272 |
6 | Patellar aplasia (HP:0006443) | 3.38829619 |
7 | Carpal bone hypoplasia (HP:0001498) | 3.27419597 |
8 | Impulsivity (HP:0100710) | 3.26312234 |
9 | Aplasia/Hypoplasia of the patella (HP:0006498) | 3.23507249 |
10 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.15648044 |
11 | Rough bone trabeculation (HP:0100670) | 3.14787323 |
12 | Microvesicular hepatic steatosis (HP:0001414) | 3.13341860 |
13 | Ependymoma (HP:0002888) | 3.13253920 |
14 | Abnormality of chromosome stability (HP:0003220) | 3.11136713 |
15 | Colon cancer (HP:0003003) | 3.10947777 |
16 | Selective tooth agenesis (HP:0001592) | 3.07655026 |
17 | Oral leukoplakia (HP:0002745) | 3.03971610 |
18 | Medulloblastoma (HP:0002885) | 3.03800027 |
19 | Embryonal renal neoplasm (HP:0011794) | 3.01852981 |
20 | Degeneration of anterior horn cells (HP:0002398) | 3.01758424 |
21 | Abnormality of the anterior horn cell (HP:0006802) | 3.01758424 |
22 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.92675389 |
23 | Abnormality of the preputium (HP:0100587) | 2.90462740 |
24 | Abnormality of the labia minora (HP:0012880) | 2.88465994 |
25 | Meckel diverticulum (HP:0002245) | 2.83975304 |
26 | Abnormal number of erythroid precursors (HP:0012131) | 2.73916739 |
27 | Myelodysplasia (HP:0002863) | 2.69162655 |
28 | Abnormality of the ileum (HP:0001549) | 2.65864480 |
29 | Absent radius (HP:0003974) | 2.64535124 |
30 | Cerebral hypomyelination (HP:0006808) | 2.61323934 |
31 | Agnosia (HP:0010524) | 2.59527191 |
32 | Neoplasm of the adrenal cortex (HP:0100641) | 2.56883018 |
33 | Premature graying of hair (HP:0002216) | 2.55726210 |
34 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.53440868 |
35 | Abnormality of methionine metabolism (HP:0010901) | 2.53252617 |
36 | Absent thumb (HP:0009777) | 2.51249842 |
37 | Aplastic anemia (HP:0001915) | 2.49296023 |
38 | Neoplasm of the pancreas (HP:0002894) | 2.45035769 |
39 | Entropion (HP:0000621) | 2.45010122 |
40 | Aplasia involving forearm bones (HP:0009822) | 2.44325973 |
41 | Absent forearm bone (HP:0003953) | 2.44325973 |
42 | Increased hepatocellular lipid droplets (HP:0006565) | 2.42787614 |
43 | Rhabdomyosarcoma (HP:0002859) | 2.42276283 |
44 | Facial hemangioma (HP:0000329) | 2.39689247 |
45 | Small intestinal stenosis (HP:0012848) | 2.38765350 |
46 | Duodenal stenosis (HP:0100867) | 2.38765350 |
47 | Abnormal trabecular bone morphology (HP:0100671) | 2.35449694 |
48 | Deviation of the thumb (HP:0009603) | 2.34465794 |
49 | Ectopic kidney (HP:0000086) | 2.33514063 |
50 | Proximal placement of thumb (HP:0009623) | 2.33268574 |
51 | Progressive muscle weakness (HP:0003323) | 2.31399314 |
52 | Abnormality of glycolysis (HP:0004366) | 2.28519586 |
53 | Bone marrow hypocellularity (HP:0005528) | 2.27944251 |
54 | Basal cell carcinoma (HP:0002671) | 2.27157836 |
55 | 11 pairs of ribs (HP:0000878) | 2.22059714 |
56 | Trismus (HP:0000211) | 2.21986571 |
57 | Increased serum pyruvate (HP:0003542) | 2.21492036 |
58 | Atresia of the external auditory canal (HP:0000413) | 2.21104274 |
59 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.21025486 |
60 | Neoplasm of the colon (HP:0100273) | 2.20574239 |
61 | Macrocytic anemia (HP:0001972) | 2.20142203 |
62 | Type I transferrin isoform profile (HP:0003642) | 2.20000294 |
63 | Abnormality of alanine metabolism (HP:0010916) | 2.19235613 |
64 | Hyperalaninemia (HP:0003348) | 2.19235613 |
65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.19235613 |
66 | Squamous cell carcinoma (HP:0002860) | 2.18780506 |
67 | Increased serum lactate (HP:0002151) | 2.16581795 |
68 | Reduced antithrombin III activity (HP:0001976) | 2.15498291 |
69 | Sloping forehead (HP:0000340) | 2.15381133 |
70 | Clubbing of toes (HP:0100760) | 2.13561276 |
71 | Glossoptosis (HP:0000162) | 2.11880289 |
72 | Multiple enchondromatosis (HP:0005701) | 2.11446226 |
73 | Pancytopenia (HP:0001876) | 2.10765509 |
74 | Neoplasm of the adrenal gland (HP:0100631) | 2.10523600 |
75 | Lipid accumulation in hepatocytes (HP:0006561) | 2.09643022 |
76 | Microretrognathia (HP:0000308) | 2.09627602 |
77 | Increased CSF lactate (HP:0002490) | 2.08862881 |
78 | Prominent nose (HP:0000448) | 2.08428328 |
79 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.08340681 |
80 | Amaurosis fugax (HP:0100576) | 2.08063643 |
81 | Abnormal lung lobation (HP:0002101) | 2.07987302 |
82 | Premature ovarian failure (HP:0008209) | 2.07478536 |
83 | Progressive external ophthalmoplegia (HP:0000590) | 2.06879816 |
84 | Volvulus (HP:0002580) | 2.06588371 |
85 | Irregular epiphyses (HP:0010582) | 2.06300074 |
86 | Sparse lateral eyebrow (HP:0005338) | 2.05976844 |
87 | Horseshoe kidney (HP:0000085) | 2.05668350 |
88 | Cellular immunodeficiency (HP:0005374) | 2.04240604 |
89 | Lymphoma (HP:0002665) | 2.03314421 |
90 | Thrombocytosis (HP:0001894) | 2.02052525 |
91 | Acute encephalopathy (HP:0006846) | 2.01535855 |
92 | Abnormality of the pons (HP:0007361) | 2.00351350 |
93 | Facial cleft (HP:0002006) | 2.00341011 |
94 | Sensory axonal neuropathy (HP:0003390) | 1.99681042 |
95 | Abnormal number of incisors (HP:0011064) | 1.99288113 |
96 | Ureteral duplication (HP:0000073) | 1.98947615 |
97 | Glioma (HP:0009733) | 1.97528673 |
98 | Tracheoesophageal fistula (HP:0002575) | 1.97176576 |
99 | Acute necrotizing encephalopathy (HP:0006965) | 1.96935824 |
100 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.96501307 |
101 | Choanal atresia (HP:0000453) | 1.95381329 |
102 | Pallor (HP:0000980) | 1.95161616 |
103 | Abnormality of the duodenum (HP:0002246) | 1.95082538 |
104 | Supernumerary spleens (HP:0009799) | 1.94582796 |
105 | Abnormality of serum amino acid levels (HP:0003112) | 1.93574778 |
106 | Cutaneous melanoma (HP:0012056) | 1.93431527 |
107 | Secondary amenorrhea (HP:0000869) | 1.93418471 |
108 | Short thumb (HP:0009778) | 1.92946888 |
109 | Astrocytoma (HP:0009592) | 1.92776564 |
110 | Abnormality of the astrocytes (HP:0100707) | 1.92776564 |
111 | Cafe-au-lait spot (HP:0000957) | 1.92671934 |
112 | Sparse eyelashes (HP:0000653) | 1.92607683 |
113 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.91847777 |
114 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.90912409 |
115 | Increased nuchal translucency (HP:0010880) | 1.89770799 |
116 | Hypoplasia of the pons (HP:0012110) | 1.89468916 |
117 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.88051388 |
118 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.88051388 |
119 | Abnormal protein glycosylation (HP:0012346) | 1.88051388 |
120 | Abnormal glycosylation (HP:0012345) | 1.88051388 |
121 | Cerebral edema (HP:0002181) | 1.86978686 |
122 | Cleft eyelid (HP:0000625) | 1.86821879 |
123 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.86367818 |
124 | Breast carcinoma (HP:0003002) | 1.85122387 |
125 | Methylmalonic acidemia (HP:0002912) | 1.84935916 |
126 | Abnormality of the calcaneus (HP:0008364) | 1.84690131 |
127 | Stillbirth (HP:0003826) | 1.84604300 |
128 | Slender long bone (HP:0003100) | 1.84535713 |
129 | Abnormality of DNA repair (HP:0003254) | 1.84472811 |
130 | Pelvic girdle muscle weakness (HP:0003749) | 1.84428961 |
131 | Stenosis of the external auditory canal (HP:0000402) | 1.83795014 |
132 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.83533068 |
133 | Overlapping toe (HP:0001845) | 1.83249098 |
134 | Duplicated collecting system (HP:0000081) | 1.81863170 |
135 | Small epiphyses (HP:0010585) | 1.79950889 |
136 | Spinal muscular atrophy (HP:0007269) | 1.79301346 |
137 | Acute myeloid leukemia (HP:0004808) | 1.79043811 |
138 | Biliary tract neoplasm (HP:0100574) | 1.78197786 |
139 | Neoplasm of the oral cavity (HP:0100649) | 1.78173521 |
140 | Triphalangeal thumb (HP:0001199) | 1.75851572 |
141 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.74881352 |
142 | Abnormality of the carotid arteries (HP:0005344) | 1.74633646 |
143 | Missing ribs (HP:0000921) | 1.72547903 |
144 | Homocystinuria (HP:0002156) | 1.71535983 |
145 | Abnormality of homocysteine metabolism (HP:0010919) | 1.71535983 |
146 | Capillary hemangiomas (HP:0005306) | 1.71070968 |
147 | Abnormality of the renal collecting system (HP:0004742) | 1.69653936 |
148 | Megaloblastic anemia (HP:0001889) | 1.69005961 |
149 | Deep philtrum (HP:0002002) | 1.67548025 |
150 | Ovarian neoplasm (HP:0100615) | 1.64754319 |
151 | Progressive macrocephaly (HP:0004481) | 1.62230580 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.51910020 |
2 | WEE1 | 4.05169231 |
3 | CDC7 | 3.83042792 |
4 | EIF2AK1 | 2.96641774 |
5 | TSSK6 | 2.83160447 |
6 | NEK2 | 2.82224318 |
7 | SRPK1 | 2.75035989 |
8 | ACVR1B | 2.72762744 |
9 | PLK4 | 2.40028851 |
10 | TTK | 2.31085997 |
11 | BRSK2 | 2.18975174 |
12 | MKNK1 | 2.16617189 |
13 | VRK2 | 2.13038515 |
14 | PLK1 | 2.01063423 |
15 | NME2 | 1.94533229 |
16 | MKNK2 | 1.94244533 |
17 | EIF2AK3 | 1.90652331 |
18 | CDK12 | 1.88203012 |
19 | PLK3 | 1.87708411 |
20 | TRIM28 | 1.81403649 |
21 | NEK1 | 1.80067351 |
22 | RPS6KA4 | 1.76836836 |
23 | AURKB | 1.70198291 |
24 | NUAK1 | 1.66780757 |
25 | ATR | 1.64773112 |
26 | PASK | 1.64215424 |
27 | CDK7 | 1.61170474 |
28 | RPS6KB2 | 1.60322714 |
29 | STK10 | 1.55006910 |
30 | EEF2K | 1.52213296 |
31 | EPHA2 | 1.48690775 |
32 | DYRK3 | 1.47329763 |
33 | CDK4 | 1.43468489 |
34 | TAF1 | 1.42813703 |
35 | CHEK2 | 1.41821770 |
36 | TLK1 | 1.41616979 |
37 | CHEK1 | 1.36280584 |
38 | MAP3K8 | 1.32621328 |
39 | VRK1 | 1.29843409 |
40 | TESK2 | 1.22965365 |
41 | ZAK | 1.20696573 |
42 | ALK | 1.12510464 |
43 | PIM1 | 1.11785024 |
44 | BRSK1 | 1.10993197 |
45 | PDK2 | 1.08768741 |
46 | AURKA | 1.08667029 |
47 | TGFBR1 | 1.08013389 |
48 | MST1R | 1.05641063 |
49 | ERBB3 | 1.04377977 |
50 | NME1 | 1.04074579 |
51 | PIM2 | 1.03489352 |
52 | ERBB4 | 1.02379845 |
53 | STK16 | 1.00170098 |
54 | ATM | 0.98987047 |
55 | STK4 | 0.97989532 |
56 | STK3 | 0.96488194 |
57 | MAP4K1 | 0.93617200 |
58 | FLT3 | 0.93576930 |
59 | CCNB1 | 0.93307670 |
60 | CDK2 | 0.92761224 |
61 | BRD4 | 0.87640334 |
62 | SCYL2 | 0.86724822 |
63 | MELK | 0.84040193 |
64 | MAP2K3 | 0.80686881 |
65 | MAP3K10 | 0.80577092 |
66 | AKT3 | 0.80459124 |
67 | BMPR1B | 0.79916328 |
68 | STK39 | 0.79418972 |
69 | TNIK | 0.78766119 |
70 | CSNK1G1 | 0.77173617 |
71 | CDK8 | 0.75020665 |
72 | CSNK2A2 | 0.74454648 |
73 | BCR | 0.73253798 |
74 | EIF2AK2 | 0.72374619 |
75 | STK38L | 0.71413052 |
76 | PAK4 | 0.71051794 |
77 | SMG1 | 0.70374979 |
78 | CDK6 | 0.67754869 |
79 | CDK1 | 0.67211292 |
80 | RPS6KA5 | 0.64056805 |
81 | PKN2 | 0.60136065 |
82 | CSNK2A1 | 0.59987379 |
83 | PLK2 | 0.57937282 |
84 | PAK1 | 0.56337188 |
85 | MAP3K12 | 0.56301098 |
86 | PNCK | 0.54731316 |
87 | MTOR | 0.53563615 |
88 | LRRK2 | 0.52480807 |
89 | LATS1 | 0.51615363 |
90 | CSNK1A1L | 0.51470644 |
91 | LATS2 | 0.51441094 |
92 | PRKCI | 0.49984955 |
93 | DAPK1 | 0.47445245 |
94 | CSNK1G3 | 0.46573127 |
95 | CSNK1E | 0.46263695 |
96 | MAP3K3 | 0.46126674 |
97 | BRAF | 0.44293077 |
98 | JAK3 | 0.44107142 |
99 | CHUK | 0.43547600 |
100 | TEC | 0.43469290 |
101 | PAK2 | 0.42732472 |
102 | MARK3 | 0.41794798 |
103 | ZAP70 | 0.37916352 |
104 | WNK4 | 0.37904922 |
105 | IKBKB | 0.37412801 |
106 | PRKDC | 0.36182935 |
107 | TXK | 0.35693706 |
108 | CDK9 | 0.34651833 |
109 | AKT2 | 0.33682569 |
110 | WNK3 | 0.33171376 |
111 | FRK | 0.31658708 |
112 | MET | 0.31126882 |
113 | BTK | 0.30075629 |
114 | MAPK14 | 0.29975738 |
115 | RPS6KB1 | 0.29527940 |
116 | MST4 | 0.28765696 |
117 | CSNK1G2 | 0.27651063 |
118 | NEK6 | 0.27328916 |
119 | TAOK2 | 0.27229738 |
120 | NEK9 | 0.26826660 |
121 | CSNK1D | 0.26661040 |
122 | MAPKAPK3 | 0.26270343 |
123 | CLK1 | 0.26139350 |
124 | FGFR1 | 0.25393114 |
125 | RAF1 | 0.25305770 |
126 | STK24 | 0.24123852 |
127 | MAP3K5 | 0.23283695 |
128 | PBK | 0.23219094 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.28933693 |
2 | * Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.22302136 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.72439636 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.44359728 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.42753755 |
6 | Spliceosome_Homo sapiens_hsa03040 | 3.26886670 |
7 | Cell cycle_Homo sapiens_hsa04110 | 2.83095862 |
8 | Ribosome_Homo sapiens_hsa03010 | 2.79517666 |
9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.76879236 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.75460218 |
11 | Base excision repair_Homo sapiens_hsa03410 | 2.72333483 |
12 | Proteasome_Homo sapiens_hsa03050 | 2.67714841 |
13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.66784730 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.50813131 |
15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.30084667 |
16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.15039197 |
17 | Basal transcription factors_Homo sapiens_hsa03022 | 2.12973350 |
18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.04759856 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.99631485 |
20 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.88830119 |
21 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.79846718 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.75168662 |
23 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.47053829 |
24 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.36041083 |
25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.26121670 |
26 | Purine metabolism_Homo sapiens_hsa00230 | 1.25520351 |
27 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.20988213 |
28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.19141215 |
29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.16782710 |
30 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.15812570 |
31 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.15096774 |
32 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.12252408 |
33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.11817819 |
34 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.10589251 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.09127961 |
36 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.06690681 |
37 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.02200185 |
38 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.92589252 |
39 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.89821234 |
40 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.88881992 |
41 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.84740898 |
42 | HTLV-I infection_Homo sapiens_hsa05166 | 0.83724655 |
43 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.82923605 |
44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.81542191 |
45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.79841831 |
46 | Parkinsons disease_Homo sapiens_hsa05012 | 0.79000091 |
47 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.77091772 |
48 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.76747729 |
49 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.76100444 |
50 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.75563337 |
51 | Huntingtons disease_Homo sapiens_hsa05016 | 0.73821697 |
52 | Thyroid cancer_Homo sapiens_hsa05216 | 0.73611633 |
53 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.72962948 |
54 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.71747386 |
55 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.71741689 |
56 | Legionellosis_Homo sapiens_hsa05134 | 0.70468019 |
57 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.68537514 |
58 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.67897186 |
59 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.67423458 |
60 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.65315114 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.62836872 |
62 | Measles_Homo sapiens_hsa05162 | 0.61465082 |
63 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59028445 |
64 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.58265760 |
65 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.57030136 |
66 | Apoptosis_Homo sapiens_hsa04210 | 0.54039139 |
67 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52901107 |
68 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.52253393 |
69 | Lysine degradation_Homo sapiens_hsa00310 | 0.51605168 |
70 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.49994289 |
71 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.49918706 |
72 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.49639015 |
73 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.49471881 |
74 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.48032783 |
75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47126992 |
76 | Hepatitis B_Homo sapiens_hsa05161 | 0.46985408 |
77 | Sulfur relay system_Homo sapiens_hsa04122 | 0.45150496 |
78 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.44857734 |
79 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.44158438 |
80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42830631 |
81 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.40840265 |
82 | Protein export_Homo sapiens_hsa03060 | 0.40634718 |
83 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.40378327 |
84 | Influenza A_Homo sapiens_hsa05164 | 0.39914746 |
85 | Colorectal cancer_Homo sapiens_hsa05210 | 0.39289961 |
86 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.37287310 |
87 | Allograft rejection_Homo sapiens_hsa05330 | 0.34801833 |
88 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.33907511 |
89 | Shigellosis_Homo sapiens_hsa05131 | 0.33804802 |
90 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.33757168 |
91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.33623986 |
92 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.33201352 |
93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.32675779 |
94 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.32618261 |
95 | Prostate cancer_Homo sapiens_hsa05215 | 0.32020732 |
96 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.29948139 |
97 | Alzheimers disease_Homo sapiens_hsa05010 | 0.28888281 |
98 | Alcoholism_Homo sapiens_hsa05034 | 0.28058496 |
99 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.28053531 |
100 | Viral myocarditis_Homo sapiens_hsa05416 | 0.27793697 |
101 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.27327283 |
102 | Pathways in cancer_Homo sapiens_hsa05200 | 0.25744162 |
103 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.25472358 |
104 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.24696807 |
105 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.24545208 |
106 | Bladder cancer_Homo sapiens_hsa05219 | 0.23280583 |
107 | Adherens junction_Homo sapiens_hsa04520 | 0.23204327 |
108 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.22933639 |
109 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.22788872 |
110 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.22360375 |
111 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.21663456 |
112 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.21615960 |
113 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.21559761 |
114 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.21051825 |
115 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.20121470 |
116 | Carbon metabolism_Homo sapiens_hsa01200 | 0.19802293 |
117 | Leishmaniasis_Homo sapiens_hsa05140 | 0.19716283 |
118 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.18309586 |
119 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.17598304 |
120 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.16300348 |
121 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.15799906 |
122 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.15527655 |
123 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.15147733 |
124 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.15037814 |
125 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.14889705 |
126 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.14754312 |
127 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.14286562 |
128 | Peroxisome_Homo sapiens_hsa04146 | 0.13792074 |
129 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.12820054 |
130 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.12632739 |
131 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.12009860 |
132 | Melanoma_Homo sapiens_hsa05218 | 0.05353001 |
133 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.04729101 |