WDR61

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: WDR61 is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (Zhu et al., 2005 [PubMed 16024656]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.06019302
2proteasome assembly (GO:0043248)4.97795756
3DNA deamination (GO:0045006)4.85042243
4respiratory electron transport chain (GO:0022904)4.57707943
5maturation of SSU-rRNA (GO:0030490)4.50003661
6electron transport chain (GO:0022900)4.49400488
7mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.27566700
8ribosomal large subunit biogenesis (GO:0042273)4.26031481
9negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.24587673
10cullin deneddylation (GO:0010388)4.09396278
11nucleobase biosynthetic process (GO:0046112)4.08701662
12ribosomal small subunit biogenesis (GO:0042274)4.05626161
13regulation of cellular amino acid metabolic process (GO:0006521)4.04013014
14positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.01281901
15protein deneddylation (GO:0000338)3.95826454
16purine nucleobase biosynthetic process (GO:0009113)3.94969327
17transcription elongation from RNA polymerase III promoter (GO:0006385)3.93898721
18termination of RNA polymerase III transcription (GO:0006386)3.93898721
19regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.93591456
20energy coupled proton transport, down electrochemical gradient (GO:0015985)3.92012571
21ATP synthesis coupled proton transport (GO:0015986)3.92012571
22negative regulation of ligase activity (GO:0051352)3.89324708
23negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.89324708
247-methylguanosine mRNA capping (GO:0006370)3.87061085
25cytochrome complex assembly (GO:0017004)3.86785109
26anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.83952796
27formation of translation preinitiation complex (GO:0001731)3.82535397
28rRNA modification (GO:0000154)3.82211719
297-methylguanosine RNA capping (GO:0009452)3.82051514
30RNA capping (GO:0036260)3.82051514
31ribonucleoprotein complex biogenesis (GO:0022613)3.80489042
32telomere maintenance via semi-conservative replication (GO:0032201)3.80160958
33SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.76114535
34GTP biosynthetic process (GO:0006183)3.74836663
35DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.73664617
36cotranslational protein targeting to membrane (GO:0006613)3.71867360
37antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.70364553
38viral transcription (GO:0019083)3.68055876
39DNA strand elongation involved in DNA replication (GO:0006271)3.67885484
40intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.67567865
41signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.67567865
42signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.67392966
43signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.67392966
44signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.67392966
45translational termination (GO:0006415)3.67236075
46L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.66384084
47regulation of mitochondrial translation (GO:0070129)3.66191618
48protein targeting to ER (GO:0045047)3.65676568
49pseudouridine synthesis (GO:0001522)3.63944831
50mitochondrial respiratory chain complex I assembly (GO:0032981)3.62541182
51NADH dehydrogenase complex assembly (GO:0010257)3.62541182
52mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.62541182
53guanosine-containing compound biosynthetic process (GO:1901070)3.60958911
54CENP-A containing nucleosome assembly (GO:0034080)3.59840952
55DNA strand elongation (GO:0022616)3.57399444
56ribosome biogenesis (GO:0042254)3.57152389
57translation (GO:0006412)3.56737700
58signal transduction involved in DNA damage checkpoint (GO:0072422)3.55436306
59signal transduction involved in DNA integrity checkpoint (GO:0072401)3.55436306
60deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.53548607
61protein localization to endoplasmic reticulum (GO:0070972)3.53527168
62cellular component biogenesis (GO:0044085)3.52569003
63chaperone-mediated protein transport (GO:0072321)3.51519859
64signal transduction involved in cell cycle checkpoint (GO:0072395)3.51222563
65chromatin remodeling at centromere (GO:0031055)3.50175010
66protein complex biogenesis (GO:0070271)3.48863213
67telomere maintenance via recombination (GO:0000722)3.48633207
68DNA replication initiation (GO:0006270)3.47642552
69positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.47425537
70antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.44924523
71UTP biosynthetic process (GO:0006228)3.44810019
72rRNA processing (GO:0006364)3.43654125
73establishment of protein localization to endoplasmic reticulum (GO:0072599)3.43563437
74DNA replication checkpoint (GO:0000076)3.41346504
75spliceosomal snRNP assembly (GO:0000387)3.40563882
76translational elongation (GO:0006414)3.36366277
77positive regulation of ligase activity (GO:0051351)3.35856974
78mitochondrial respiratory chain complex assembly (GO:0033108)3.33941781
79protein neddylation (GO:0045116)3.33641151
80DNA double-strand break processing (GO:0000729)3.29062282
81rRNA metabolic process (GO:0016072)3.28158395
82transcription-coupled nucleotide-excision repair (GO:0006283)3.27495645
83protein targeting to mitochondrion (GO:0006626)3.27181937
84peptidyl-histidine modification (GO:0018202)3.25610598
85translational initiation (GO:0006413)3.21179506
86mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.21063127
87termination of RNA polymerase I transcription (GO:0006363)3.20662875
88amino acid salvage (GO:0043102)3.19687846
89L-methionine salvage (GO:0071267)3.19687846
90L-methionine biosynthetic process (GO:0071265)3.19687846
91maturation of 5.8S rRNA (GO:0000460)3.19211405
92protein localization to mitochondrion (GO:0070585)3.15422762
93mitotic recombination (GO:0006312)3.14632093
94establishment of protein localization to mitochondrial membrane (GO:0090151)3.14232410
95ribosome assembly (GO:0042255)3.13795937
96transcription elongation from RNA polymerase I promoter (GO:0006362)3.13675032
97oxidative phosphorylation (GO:0006119)3.13249192
98establishment of integrated proviral latency (GO:0075713)3.13013189
99rRNA methylation (GO:0031167)3.11634244
100mitotic metaphase plate congression (GO:0007080)3.10646228
101nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.10359142
102respiratory chain complex IV assembly (GO:0008535)3.08691839
103tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.07289881
104RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.07289881
105UTP metabolic process (GO:0046051)3.06866273
106regulation of ubiquitin-protein transferase activity (GO:0051438)3.06082067
107exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.05600668
108telomere maintenance via telomere lengthening (GO:0010833)3.05597294
109DNA catabolic process, exonucleolytic (GO:0000738)3.04088841
110establishment of protein localization to mitochondrion (GO:0072655)3.03205744
111deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.02743855
112G1/S transition of mitotic cell cycle (GO:0000082)3.02552387
113aldehyde catabolic process (GO:0046185)3.02168064
114protein-cofactor linkage (GO:0018065)3.01479029
115regulation of ligase activity (GO:0051340)2.99281560
116ATP biosynthetic process (GO:0006754)2.99161229
117regulation of mitotic spindle checkpoint (GO:1903504)2.98352071
118regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.98352071
119purine nucleoside triphosphate biosynthetic process (GO:0009145)2.96045593
120pteridine-containing compound biosynthetic process (GO:0042559)2.95263941
121IMP biosynthetic process (GO:0006188)2.94867750
122histone exchange (GO:0043486)2.94281777
123regulation of cellular amine metabolic process (GO:0033238)2.93407713
124protein K6-linked ubiquitination (GO:0085020)2.91911119
125hydrogen ion transmembrane transport (GO:1902600)2.91823283
126DNA ligation (GO:0006266)2.91621351
127purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.89829245
128nucleotide-excision repair, DNA gap filling (GO:0006297)2.88592453
129water-soluble vitamin biosynthetic process (GO:0042364)2.86461453
130lactate metabolic process (GO:0006089)2.85880930
131histone H2A acetylation (GO:0043968)2.83544973
132mitochondrial transport (GO:0006839)2.81752093
133transcription from mitochondrial promoter (GO:0006390)2.81162834
134aerobic respiration (GO:0009060)2.80061077
135replication fork processing (GO:0031297)2.77368097
136purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.75703606
137purine nucleoside monophosphate biosynthetic process (GO:0009127)2.75703606
138non-recombinational repair (GO:0000726)2.75659077

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.10945133
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.85272106
3* MYC_18555785_ChIP-Seq_MESCs_Mouse4.31798858
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.30459510
5EST1_17652178_ChIP-ChIP_JURKAT_Human4.17921786
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.95437300
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.72980175
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.51505505
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.44834746
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.31294921
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.22020136
12MYC_18358816_ChIP-ChIP_MESCs_Mouse3.06445382
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.98751985
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.91659863
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.89506803
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.85790191
17* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.85439405
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.84255783
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.79184849
20VDR_23849224_ChIP-Seq_CD4+_Human2.72257550
21* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.64344144
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.49263384
23* SRF_21415370_ChIP-Seq_HL-1_Mouse2.46418228
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.43573922
25DCP1A_22483619_ChIP-Seq_HELA_Human2.38213366
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.38122699
27PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.35097024
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34596785
29FOXP3_21729870_ChIP-Seq_TREG_Human2.31681388
30THAP11_20581084_ChIP-Seq_MESCs_Mouse2.26340819
31ELK1_19687146_ChIP-ChIP_HELA_Human2.23338675
32XRN2_22483619_ChIP-Seq_HELA_Human2.22545189
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.13270921
34GABP_19822575_ChIP-Seq_HepG2_Human2.11518574
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.09686838
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.94462980
37HOXB4_20404135_ChIP-ChIP_EML_Mouse1.91612291
38TTF2_22483619_ChIP-Seq_HELA_Human1.89641387
39SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89443760
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82985637
41ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.78741911
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.72257354
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71482976
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.70709558
45EWS_26573619_Chip-Seq_HEK293_Human1.62822807
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62166193
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.59996276
48AR_21909140_ChIP-Seq_LNCAP_Human1.55792945
49PADI4_21655091_ChIP-ChIP_MCF-7_Human1.55345969
50ERG_20887958_ChIP-Seq_HPC-7_Mouse1.54585669
51VDR_22108803_ChIP-Seq_LS180_Human1.54006573
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.52452766
53CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.50272872
54ZNF274_21170338_ChIP-Seq_K562_Hela1.48141110
55* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.45313191
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.45257036
57CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.44435243
58NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41933456
59ELK1_22589737_ChIP-Seq_MCF10A_Human1.40081445
60FOXM1_23109430_ChIP-Seq_U2OS_Human1.38807094
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.36503819
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33965521
63FUS_26573619_Chip-Seq_HEK293_Human1.33423372
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.30635969
65CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.27438482
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.24112811
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.23875159
68IGF1R_20145208_ChIP-Seq_DFB_Human1.21880438
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20011665
70* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18184985
71* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.16792164
72MYC_18940864_ChIP-ChIP_HL60_Human1.16037638
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15827540
74FLI1_27457419_Chip-Seq_LIVER_Mouse1.15661588
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13497365
76TAF15_26573619_Chip-Seq_HEK293_Human1.12546914
77CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12233523
78HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.11984962
79KDM5A_27292631_Chip-Seq_BREAST_Human1.11644522
80CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.10647385
81TFEB_21752829_ChIP-Seq_HELA_Human1.07331203
82CIITA_25753668_ChIP-Seq_RAJI_Human1.07103796
83IRF1_19129219_ChIP-ChIP_H3396_Human1.05110288
84SALL1_21062744_ChIP-ChIP_HESCs_Human1.02846150
85HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.99894374
86POU5F1_16153702_ChIP-ChIP_HESCs_Human0.98203336
87SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97465215
88TP53_22573176_ChIP-Seq_HFKS_Human0.96554701
89DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96032290
90* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.95636962
91NANOG_16153702_ChIP-ChIP_HESCs_Human0.95024112
92E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.94738925
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92193492
94* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.91893066
95CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.91792609
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.90706373
97SOX2_18555785_ChIP-Seq_MESCs_Mouse0.89935067
98STAT3_1855785_ChIP-Seq_MESCs_Mouse0.86265278
99SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.84001072
100ZFP57_27257070_Chip-Seq_ESCs_Mouse0.82986054
101SOX2_16153702_ChIP-ChIP_HESCs_Human0.82980180
102KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.82693204
103ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82535796
104P300_19829295_ChIP-Seq_ESCs_Human0.80791637
105PCGF2_27294783_Chip-Seq_ESCs_Mouse0.80582845
106HTT_18923047_ChIP-ChIP_STHdh_Human0.79733095
107SALL4_22934838_ChIP-ChIP_CD34+_Human0.78682132
108MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.78524542
109* SPI1_23547873_ChIP-Seq_NB4_Human0.78301506
110ELF5_23300383_ChIP-Seq_T47D_Human0.77024137
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.76081042
112PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75672611
113CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.75229701
114* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75115774
115IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.74963696
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.74807702
117GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.72700308
118FOXA1_25329375_ChIP-Seq_VCAP_Human0.72147223
119FOXA1_27270436_Chip-Seq_PROSTATE_Human0.72147223
120POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.70523858
121EGR1_23403033_ChIP-Seq_LIVER_Mouse0.69493149
122* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.66604299
123* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.64705149
124CTCF_18555785_ChIP-Seq_MESCs_Mouse0.63980845
125NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.63603496
126SOX2_18692474_ChIP-Seq_MEFs_Mouse0.60308666
127FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.59915441
128* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.58071196

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.09766147
2MP0004957_abnormal_blastocyst_morpholog4.16098364
3MP0003806_abnormal_nucleotide_metabolis3.86082501
4MP0009379_abnormal_foot_pigmentation3.82946092
5MP0010094_abnormal_chromosome_stability3.55791503
6MP0008058_abnormal_DNA_repair3.40298160
7MP0008057_abnormal_DNA_replication3.30592533
8MP0003111_abnormal_nucleus_morphology3.20016838
9MP0003186_abnormal_redox_activity3.14574376
10MP0003077_abnormal_cell_cycle3.07676775
11MP0002102_abnormal_ear_morphology2.84774437
12MP0008007_abnormal_cellular_replicative2.71125193
13MP0009697_abnormal_copulation2.67633876
14MP0003786_premature_aging2.50580700
15MP0008932_abnormal_embryonic_tissue2.47303027
16MP0006072_abnormal_retinal_apoptosis2.42827010
17MP0002837_dystrophic_cardiac_calcinosis2.30811630
18MP0006036_abnormal_mitochondrial_physio2.25981868
19MP0002132_abnormal_respiratory_system2.16417331
20MP0008877_abnormal_DNA_methylation2.12389180
21MP0003123_paternal_imprinting2.03795022
22MP0003718_maternal_effect2.02875493
23MP0006035_abnormal_mitochondrial_morpho1.97014864
24MP0001764_abnormal_homeostasis1.93932656
25MP0006292_abnormal_olfactory_placode1.86147699
26MP0003011_delayed_dark_adaptation1.81671472
27MP0001984_abnormal_olfaction1.81215033
28MP0004147_increased_porphyrin_level1.79572626
29MP0005253_abnormal_eye_physiology1.64938617
30MP0009046_muscle_twitch1.62112715
31MP0001529_abnormal_vocalization1.58665424
32MP0000566_synostosis1.54520611
33MP0001188_hyperpigmentation1.51525591
34MP0003880_abnormal_central_pattern1.50087595
35MP0002396_abnormal_hematopoietic_system1.49788565
36MP0001986_abnormal_taste_sensitivity1.46621377
37MP0002938_white_spotting1.46328211
38MP0002876_abnormal_thyroid_physiology1.44425326
39MP0005408_hypopigmentation1.43232246
40MP0003136_yellow_coat_color1.41875216
41MP0000372_irregular_coat_pigmentation1.40503357
42MP0000490_abnormal_crypts_of1.34400800
43MP0003195_calcinosis1.33471611
44MP0002090_abnormal_vision1.31599304
45MP0002638_abnormal_pupillary_reflex1.27038474
46MP0002163_abnormal_gland_morphology1.26925654
47MP0005551_abnormal_eye_electrophysiolog1.25448706
48MP0005389_reproductive_system_phenotype1.23565101
49MP0005075_abnormal_melanosome_morpholog1.23087709
50MP0001730_embryonic_growth_arrest1.21810567
51MP0009333_abnormal_splenocyte_physiolog1.21170152
52MP0004215_abnormal_myocardial_fiber1.17690593
53MP0002160_abnormal_reproductive_system1.16847997
54MP0003315_abnormal_perineum_morphology1.16627371
55MP0000350_abnormal_cell_proliferation1.16068650
56MP0006054_spinal_hemorrhage1.16065990
57MP0005646_abnormal_pituitary_gland1.15759466
58MP0001919_abnormal_reproductive_system1.14556669
59MP0000313_abnormal_cell_death1.12537468
60MP0002736_abnormal_nociception_after1.12411014
61MP0005379_endocrine/exocrine_gland_phen1.11698413
62MP0001853_heart_inflammation1.10052580
63MP0008872_abnormal_physiological_respon1.09140750
64MP0010386_abnormal_urinary_bladder1.08470257
65MP0005266_abnormal_metabolism1.07486381
66MP0000358_abnormal_cell_content/1.06246184
67MP0001905_abnormal_dopamine_level1.04772632
68MP0002277_abnormal_respiratory_mucosa1.01598208
69MP0001968_abnormal_touch/_nociception1.00274867
70MP0002234_abnormal_pharynx_morphology0.99273029
71MP0001542_abnormal_bone_strength0.99121179
72MP0001661_extended_life_span0.98390531
73MP0005636_abnormal_mineral_homeostasis0.95842120
74MP0002210_abnormal_sex_determination0.95735820
75MP0008875_abnormal_xenobiotic_pharmacok0.95708476
76MP0003656_abnormal_erythrocyte_physiolo0.95456980
77MP0005645_abnormal_hypothalamus_physiol0.94528198
78MP0002019_abnormal_tumor_incidence0.93413298
79MP0004142_abnormal_muscle_tone0.90948520
80MP0005084_abnormal_gallbladder_morpholo0.89243186
81MP0001293_anophthalmia0.88287732
82MP0003941_abnormal_skin_development0.87904775
83MP0000631_abnormal_neuroendocrine_gland0.86327935
84MP0003283_abnormal_digestive_organ0.85878810
85MP0002095_abnormal_skin_pigmentation0.85869604
86MP0002080_prenatal_lethality0.84844531
87MP0002272_abnormal_nervous_system0.84788551
88MP0001697_abnormal_embryo_size0.84388173
89MP0005171_absent_coat_pigmentation0.84209664
90MP0004133_heterotaxia0.83447091
91MP0001119_abnormal_female_reproductive0.83437273
92MP0003724_increased_susceptibility_to0.83375474
93MP0000015_abnormal_ear_pigmentation0.83265984
94MP0005376_homeostasis/metabolism_phenot0.81576319
95MP0001145_abnormal_male_reproductive0.81351923
96MP0005332_abnormal_amino_acid0.80926695
97MP0002139_abnormal_hepatobiliary_system0.80063763
98MP0000516_abnormal_urinary_system0.80049435
99MP0005367_renal/urinary_system_phenotyp0.80049435
100MP0001324_abnormal_eye_pigmentation0.78242005
101MP0001545_abnormal_hematopoietic_system0.77024743
102MP0005397_hematopoietic_system_phenotyp0.77024743
103MP0005174_abnormal_tail_pigmentation0.76542175
104MP0009785_altered_susceptibility_to0.76211816
105MP0003698_abnormal_male_reproductive0.75569812
106MP0002751_abnormal_autonomic_nervous0.75340146
107MP0000678_abnormal_parathyroid_gland0.75322423
108MP0002148_abnormal_hypersensitivity_rea0.75317644
109MP0000653_abnormal_sex_gland0.75032973
110MP0008260_abnormal_autophagy0.74716886
111MP0005220_abnormal_exocrine_pancreas0.74286948
112MP0005391_vision/eye_phenotype0.74101563
113MP0005410_abnormal_fertilization0.72661355
114MP0001929_abnormal_gametogenesis0.72327075
115MP0002909_abnormal_adrenal_gland0.71348452
116MP0003121_genomic_imprinting0.70278513
117MP0000647_abnormal_sebaceous_gland0.67663785
118MP0000689_abnormal_spleen_morphology0.67212422
119MP0004782_abnormal_surfactant_physiolog0.66238226
120MP0003763_abnormal_thymus_physiology0.65627188
121MP0008789_abnormal_olfactory_epithelium0.65330776
122MP0003567_abnormal_fetal_cardiomyocyte0.65032531
123MP0008873_increased_physiological_sensi0.63820094
124MP0002722_abnormal_immune_system0.63634393
125MP0000681_abnormal_thyroid_gland0.62331212
126MP0001672_abnormal_embryogenesis/_devel0.61796415
127MP0005380_embryogenesis_phenotype0.61796415
128MP0003890_abnormal_embryonic-extraembry0.61620991
129MP0008995_early_reproductive_senescence0.60880184
130MP0000427_abnormal_hair_cycle0.59257465
131MP0002282_abnormal_trachea_morphology0.58795580
132MP0000858_altered_metastatic_potential0.58216142
133MP0001727_abnormal_embryo_implantation0.58186033
134MP0003646_muscle_fatigue0.58014457
135MP0001485_abnormal_pinna_reflex0.57803605
136MP0005319_abnormal_enzyme/_coenzyme0.56095381
137MP0005671_abnormal_response_to0.56049632
138MP0003937_abnormal_limbs/digits/tail_de0.55939018
139MP0001835_abnormal_antigen_presentation0.54006976
140MP0002429_abnormal_blood_cell0.53691906
141MP0001756_abnormal_urination0.53575645

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.83364127
2Mitochondrial inheritance (HP:0001427)4.52525025
3Abnormal mitochondria in muscle tissue (HP:0008316)4.51209023
4Hepatocellular necrosis (HP:0001404)4.36871292
5Increased CSF lactate (HP:0002490)4.21587523
6Hepatic necrosis (HP:0002605)4.19355478
7Abnormality of cells of the erythroid lineage (HP:0012130)4.10730140
8Acute encephalopathy (HP:0006846)4.03354990
9Abnormal number of erythroid precursors (HP:0012131)3.95356725
103-Methylglutaconic aciduria (HP:0003535)3.92911135
11Progressive macrocephaly (HP:0004481)3.84391292
12Decreased activity of mitochondrial respiratory chain (HP:0008972)3.68678011
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.68678011
14Birth length less than 3rd percentile (HP:0003561)3.67343335
15Increased serum lactate (HP:0002151)3.57337247
16Increased hepatocellular lipid droplets (HP:0006565)3.53955736
17Reticulocytopenia (HP:0001896)3.42983685
18Lipid accumulation in hepatocytes (HP:0006561)3.28933247
19Increased serum pyruvate (HP:0003542)3.23685933
20Abnormality of glycolysis (HP:0004366)3.23685933
21Type I transferrin isoform profile (HP:0003642)3.19952922
22Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.04855632
23Lactic acidosis (HP:0003128)3.03901000
24Renal Fanconi syndrome (HP:0001994)2.98138470
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.96626712
26Oral leukoplakia (HP:0002745)2.96039888
27Cerebral edema (HP:0002181)2.93892459
28Exercise intolerance (HP:0003546)2.92936864
29Microvesicular hepatic steatosis (HP:0001414)2.91863209
30Macrocytic anemia (HP:0001972)2.90643711
31Abnormality of methionine metabolism (HP:0010901)2.85849986
32Aplastic anemia (HP:0001915)2.85522695
33Respiratory failure (HP:0002878)2.81614556
34Breast hypoplasia (HP:0003187)2.80345918
35Increased intramyocellular lipid droplets (HP:0012240)2.77593572
36Methylmalonic acidemia (HP:0002912)2.76756160
3711 pairs of ribs (HP:0000878)2.70576384
38Exertional dyspnea (HP:0002875)2.69801488
39Rough bone trabeculation (HP:0100670)2.65469150
40Carpal bone hypoplasia (HP:0001498)2.64461685
41Abnormality of the heme biosynthetic pathway (HP:0010472)2.63656246
42Aplasia/hypoplasia of the uterus (HP:0008684)2.59250555
43Pancreatic fibrosis (HP:0100732)2.56955787
44Reduced antithrombin III activity (HP:0001976)2.50661325
45True hermaphroditism (HP:0010459)2.49104907
46Abnormality of aspartate family amino acid metabolism (HP:0010899)2.46625967
47Pancreatic cysts (HP:0001737)2.42619521
48Abnormality of serum amino acid levels (HP:0003112)2.42096022
49Degeneration of anterior horn cells (HP:0002398)2.41641309
50Abnormality of the anterior horn cell (HP:0006802)2.41641309
51CNS demyelination (HP:0007305)2.35713293
52Congenital, generalized hypertrichosis (HP:0004540)2.34851486
53Cerebral hypomyelination (HP:0006808)2.34703039
54Respiratory difficulties (HP:0002880)2.33172522
55Increased muscle lipid content (HP:0009058)2.31838380
56Methylmalonic aciduria (HP:0012120)2.28936455
57Microretrognathia (HP:0000308)2.28505900
58Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28068742
59Pallor (HP:0000980)2.27215099
60Neoplasm of the adrenal gland (HP:0100631)2.26346783
61Abnormal protein glycosylation (HP:0012346)2.25684125
62Abnormal glycosylation (HP:0012345)2.25684125
63Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.25684125
64Abnormal protein N-linked glycosylation (HP:0012347)2.25684125
65Irregular epiphyses (HP:0010582)2.20934105
66Abnormality of the labia minora (HP:0012880)2.20826622
67Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.19592663
68Abnormality of alanine metabolism (HP:0010916)2.19592663
69Hyperalaninemia (HP:0003348)2.19592663
70Nausea (HP:0002018)2.19012745
71Glycosuria (HP:0003076)2.16011518
72Abnormality of urine glucose concentration (HP:0011016)2.16011518
73Medial flaring of the eyebrow (HP:0010747)2.15335900
74Abnormality of midbrain morphology (HP:0002418)2.14712489
75Molar tooth sign on MRI (HP:0002419)2.14712489
76Secondary amenorrhea (HP:0000869)2.14066575
77Optic disc pallor (HP:0000543)2.09771906
78Leukodystrophy (HP:0002415)2.09608706
79Generalized aminoaciduria (HP:0002909)2.08574573
80Hypoglycemic coma (HP:0001325)2.07671580
81Pancytopenia (HP:0001876)2.05901636
82Abnormality of pyrimidine metabolism (HP:0004353)2.04939681
83Premature graying of hair (HP:0002216)2.02368973
84Lethargy (HP:0001254)2.02368957
85Emotional lability (HP:0000712)2.00782713
86Hypothermia (HP:0002045)2.00742804
87Abnormality of chromosome stability (HP:0003220)2.00696917
88Megaloblastic anemia (HP:0001889)2.00687481
89Hypoplasia of the uterus (HP:0000013)1.98055272
90Poor head control (HP:0002421)1.97997152
91Hypobetalipoproteinemia (HP:0003563)1.97884931
92Testicular atrophy (HP:0000029)1.97525015
93Aplasia/Hypoplasia of the uvula (HP:0010293)1.97410878
94Hyperglycinemia (HP:0002154)1.95938558
95Abnormality of renal resorption (HP:0011038)1.95016277
96Abnormal trabecular bone morphology (HP:0100671)1.93424229
97Hyperglycinuria (HP:0003108)1.89816884
98Abnormality of the preputium (HP:0100587)1.89440443
99Chromosomal breakage induced by crosslinking agents (HP:0003221)1.88297543
100Abnormality of aromatic amino acid family metabolism (HP:0004338)1.87796952
101Renal cortical cysts (HP:0000803)1.86024627
102Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.84276838
103Patellar aplasia (HP:0006443)1.81735453
104Hyperinsulinemic hypoglycemia (HP:0000825)1.81124491
105Meckel diverticulum (HP:0002245)1.81049587
106Absent thumb (HP:0009777)1.80687713
107Congenital primary aphakia (HP:0007707)1.80456238
108Abnormality of vitamin B metabolism (HP:0004340)1.78655686
109Conjunctival hamartoma (HP:0100780)1.78298598
110Abnormality of the ileum (HP:0001549)1.78175767
111Bone marrow hypocellularity (HP:0005528)1.77103703
112Spastic paraparesis (HP:0002313)1.76899021
113Hyperphosphaturia (HP:0003109)1.76547896
114X-linked dominant inheritance (HP:0001423)1.76451798
115Sparse eyelashes (HP:0000653)1.76310270
116Type 2 muscle fiber atrophy (HP:0003554)1.75212945
117Abnormality of dicarboxylic acid metabolism (HP:0010995)1.74460269
118Aplasia/Hypoplasia of the patella (HP:0006498)1.74147161
119Cerebral palsy (HP:0100021)1.73676516
120Aplasia/Hypoplasia of the tongue (HP:0010295)1.72811772
121Horseshoe kidney (HP:0000085)1.72737618
122Thrombocytosis (HP:0001894)1.72701217
123Cellular immunodeficiency (HP:0005374)1.72652234
124Nephronophthisis (HP:0000090)1.71698918
125Nephrogenic diabetes insipidus (HP:0009806)1.70118858
126Abnormal spermatogenesis (HP:0008669)1.69789767
127Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.68840647
128Sclerocornea (HP:0000647)1.68676664
129Abnormality of serine family amino acid metabolism (HP:0010894)1.68305120
130Abnormality of glycine metabolism (HP:0010895)1.68305120
131Palpitations (HP:0001962)1.67512829
132Chromsome breakage (HP:0040012)1.66652536
133Unsteady gait (HP:0002317)1.66453077
134CNS hypomyelination (HP:0003429)1.63503758
135Gliosis (HP:0002171)1.63145856
136Dicarboxylic aciduria (HP:0003215)1.60854073

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.45047737
2STK164.10005128
3WEE13.53890529
4VRK23.44769154
5EIF2AK13.36095377
6EIF2AK32.92622112
7SRPK12.82514951
8NME22.70327226
9TSSK62.45415259
10ACVR1B2.33356674
11VRK12.31711543
12TRIM282.03567243
13PBK2.02216563
14BRSK22.01254749
15MST41.95664475
16PIM21.87175639
17CDC71.85809257
18MKNK11.85407915
19PLK41.82724702
20NME11.82412434
21MKNK21.67366245
22PASK1.57129346
23ZAK1.50618509
24ERBB31.45078965
25CCNB11.44671156
26BRAF1.44488203
27ARAF1.43866852
28TLK11.43048434
29PLK31.41933659
30CDK81.40819740
31SCYL21.38166043
32BCKDK1.37057644
33PLK11.36405639
34TTK1.29553009
35BMPR1B1.28503788
36TESK21.23000784
37TAF11.20807035
38MUSK1.19602311
39MAP3K121.15573307
40MAP4K21.13718237
41TGFBR11.10504155
42AURKB1.09869098
43STK38L1.09543109
44EIF2AK21.09516343
45AURKA1.05545672
46CSNK1G11.04383021
47BRSK10.98392566
48ATR0.98181394
49CSNK1G20.97988511
50DYRK30.93266568
51NEK10.91769365
52AKT30.91650469
53MYLK0.90517055
54MAPKAPK50.89177322
55GRK10.87410851
56ABL20.84235689
57CDK70.84079258
58CSNK1A1L0.82692516
59MAP3K30.82025924
60TEC0.79714242
61TESK10.79696899
62CSNK2A10.79455288
63TAOK20.78007426
64EPHA20.77856836
65INSRR0.73223363
66CSNK2A20.72137825
67LIMK10.71337832
68RPS6KB20.71146209
69SIK30.69103877
70CHEK20.69014682
71IRAK30.67289779
72CASK0.65386859
73BMPR20.64772466
74PIK3CG0.63216562
75MAP3K140.62742843
76PINK10.62554815
77KDR0.62440492
78WNK30.62219370
79DAPK10.60954486
80ADRBK20.59196453
81RPS6KA40.58229195
82MINK10.57865437
83IRAK40.56703696
84FRK0.55077977
85FLT30.54792153
86PNCK0.54633454
87MAP3K40.54445774
88PIM10.54387872
89PRKCI0.54038714
90BRD40.53182273
91BCR0.52999449
92STK30.51978015
93STK240.50379900
94ILK0.50183879
95STK40.49136630
96PRKCG0.48552393
97NEK90.47356761
98PRKCE0.46551557
99MAP3K110.46451893
100YES10.45900909
101NEK20.45224812
102TNIK0.44879245
103OXSR10.44872576
104CHEK10.44844801
105FGFR20.42980103
106MAP3K80.41834452
107PLK20.41695826
108PAK40.40762638
109RPS6KA50.39959870
110CDK190.38294209
111FER0.37473072
112CSNK1G30.37233225
113NUAK10.36598476
114PDK20.36016862
115PAK10.35674712
116PDK30.35637794
117PDK40.35637794
118ATM0.35547749
119CLK10.35257450
120TIE10.35093248
121CSNK1A10.34930757
122STK390.34904612
123NEK60.34597755
124DYRK20.34359646
125MAP2K70.33687514
126CAMK2D0.33319702
127IKBKB0.31662576
128TXK0.31624483
129LYN0.31439885
130CSNK1E0.31272845
131MARK30.29962570
132DAPK30.29825654
133PHKG10.29270011
134PHKG20.29270011

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.57998340
2Ribosome_Homo sapiens_hsa030103.95298908
3RNA polymerase_Homo sapiens_hsa030203.55901554
4DNA replication_Homo sapiens_hsa030303.45585836
5Protein export_Homo sapiens_hsa030603.20659778
6Mismatch repair_Homo sapiens_hsa034303.04879301
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.85306082
8Oxidative phosphorylation_Homo sapiens_hsa001902.83044237
9Pyrimidine metabolism_Homo sapiens_hsa002402.66610593
10Homologous recombination_Homo sapiens_hsa034402.46917238
11Spliceosome_Homo sapiens_hsa030402.45462951
12Parkinsons disease_Homo sapiens_hsa050122.44870777
13Nucleotide excision repair_Homo sapiens_hsa034202.29249937
14RNA transport_Homo sapiens_hsa030132.06125191
15Base excision repair_Homo sapiens_hsa034101.98384009
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.98187494
17Huntingtons disease_Homo sapiens_hsa050161.96248198
18One carbon pool by folate_Homo sapiens_hsa006701.80184604
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.79542941
20Basal transcription factors_Homo sapiens_hsa030221.74903035
21* RNA degradation_Homo sapiens_hsa030181.53374359
22Alzheimers disease_Homo sapiens_hsa050101.52360640
23Purine metabolism_Homo sapiens_hsa002301.51581883
24Folate biosynthesis_Homo sapiens_hsa007901.50162722
25Fanconi anemia pathway_Homo sapiens_hsa034601.49377966
26Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.47101230
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.46053510
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.44590623
29Non-homologous end-joining_Homo sapiens_hsa034501.42946836
30Cell cycle_Homo sapiens_hsa041101.41128301
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.30516730
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.20932142
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.18808386
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.16811976
35Butanoate metabolism_Homo sapiens_hsa006501.11936439
36Glutathione metabolism_Homo sapiens_hsa004801.11873481
37Sulfur relay system_Homo sapiens_hsa041221.08503707
38Selenocompound metabolism_Homo sapiens_hsa004500.92478590
39Pentose phosphate pathway_Homo sapiens_hsa000300.89708844
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89140181
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86803205
42Maturity onset diabetes of the young_Homo sapiens_hsa049500.85330078
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.85188392
44Fatty acid metabolism_Homo sapiens_hsa012120.82180274
45Sulfur metabolism_Homo sapiens_hsa009200.81438326
46p53 signaling pathway_Homo sapiens_hsa041150.81080656
47Vitamin B6 metabolism_Homo sapiens_hsa007500.80200502
48Metabolic pathways_Homo sapiens_hsa011000.78928270
49Epstein-Barr virus infection_Homo sapiens_hsa051690.78184613
50Nitrogen metabolism_Homo sapiens_hsa009100.75744493
51Fatty acid elongation_Homo sapiens_hsa000620.74460083
52Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.74308188
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.73529885
54Fatty acid degradation_Homo sapiens_hsa000710.71979716
55Carbon metabolism_Homo sapiens_hsa012000.71489913
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70890843
57Tryptophan metabolism_Homo sapiens_hsa003800.69771567
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.68903162
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.68820220
60Phototransduction_Homo sapiens_hsa047440.66732990
61Pyruvate metabolism_Homo sapiens_hsa006200.66725955
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65701270
63Biosynthesis of amino acids_Homo sapiens_hsa012300.64769543
64Arachidonic acid metabolism_Homo sapiens_hsa005900.63408127
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61844594
66Systemic lupus erythematosus_Homo sapiens_hsa053220.60015317
67N-Glycan biosynthesis_Homo sapiens_hsa005100.59018754
68Peroxisome_Homo sapiens_hsa041460.58787639
69Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.57864758
70mRNA surveillance pathway_Homo sapiens_hsa030150.57695498
71Legionellosis_Homo sapiens_hsa051340.57674735
72Vibrio cholerae infection_Homo sapiens_hsa051100.55380356
73Regulation of autophagy_Homo sapiens_hsa041400.54933009
74Chemical carcinogenesis_Homo sapiens_hsa052040.53847041
75Fructose and mannose metabolism_Homo sapiens_hsa000510.52177324
76Galactose metabolism_Homo sapiens_hsa000520.50968782
77Antigen processing and presentation_Homo sapiens_hsa046120.49584273
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.49201216
79Collecting duct acid secretion_Homo sapiens_hsa049660.48971201
80Primary bile acid biosynthesis_Homo sapiens_hsa001200.47772625
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.46122669
82Asthma_Homo sapiens_hsa053100.46083416
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45921190
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44942490
85Phenylalanine metabolism_Homo sapiens_hsa003600.44505624
86Tyrosine metabolism_Homo sapiens_hsa003500.42052311
87Arginine and proline metabolism_Homo sapiens_hsa003300.40949618
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40022007
89Cyanoamino acid metabolism_Homo sapiens_hsa004600.38167626
90Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38102556
91Histidine metabolism_Homo sapiens_hsa003400.37722744
92Retinol metabolism_Homo sapiens_hsa008300.37336984
93Other glycan degradation_Homo sapiens_hsa005110.36316755
94Propanoate metabolism_Homo sapiens_hsa006400.35676424
95Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.34086337
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34010536
97Herpes simplex infection_Homo sapiens_hsa051680.33406547
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.31700992
99Steroid hormone biosynthesis_Homo sapiens_hsa001400.30956805
100Linoleic acid metabolism_Homo sapiens_hsa005910.30257869
101beta-Alanine metabolism_Homo sapiens_hsa004100.27250570
102Rheumatoid arthritis_Homo sapiens_hsa053230.25652657
103Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.25312680
104Olfactory transduction_Homo sapiens_hsa047400.21007371
105Cardiac muscle contraction_Homo sapiens_hsa042600.20818141
106Steroid biosynthesis_Homo sapiens_hsa001000.20530505
107Type I diabetes mellitus_Homo sapiens_hsa049400.20485920
108Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.19016149
109alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18645878
110Phagosome_Homo sapiens_hsa041450.18297980
111Sphingolipid metabolism_Homo sapiens_hsa006000.17261847
112Oocyte meiosis_Homo sapiens_hsa041140.16614336
113Ether lipid metabolism_Homo sapiens_hsa005650.15713584
114Viral carcinogenesis_Homo sapiens_hsa052030.15275368
115Caffeine metabolism_Homo sapiens_hsa002320.12038995

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