WDR64

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.66116514
2spermatid development (GO:0007286)9.61064450
3motile cilium assembly (GO:0044458)9.23052293
4regulation of cilium movement (GO:0003352)8.83253820
5cilium movement (GO:0003341)8.48917685
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.63180936
7single fertilization (GO:0007338)7.61790523
8male meiosis (GO:0007140)7.20235121
9sperm capacitation (GO:0048240)7.19756716
10piRNA metabolic process (GO:0034587)7.06413705
11synaptonemal complex organization (GO:0070193)7.03769446
12synaptonemal complex assembly (GO:0007130)6.82017371
13negative regulation of inclusion body assembly (GO:0090084)6.64866557
14response to pheromone (GO:0019236)6.60330719
15microtubule depolymerization (GO:0007019)6.50517966
16spermatogenesis (GO:0007283)6.48615211
17male gamete generation (GO:0048232)6.46337979
18fertilization (GO:0009566)6.40253639
19organic cation transport (GO:0015695)6.19299757
20gamete generation (GO:0007276)5.95159720
21establishment of protein localization to Golgi (GO:0072600)5.91431664
22protein targeting to Golgi (GO:0000042)5.66559424
23regulation of inclusion body assembly (GO:0090083)5.63792126
24cellular ketone body metabolic process (GO:0046950)5.51074405
25calcium ion-dependent exocytosis (GO:0017156)5.42643256
26ventricular system development (GO:0021591)5.41777708
27germ cell development (GO:0007281)5.37723051
28cellular process involved in reproduction in multicellular organism (GO:0022412)5.35924384
29retrograde transport, vesicle recycling within Golgi (GO:0000301)5.20492996
30spermatid nucleus differentiation (GO:0007289)5.18992908
31regulation of microtubule-based movement (GO:0060632)5.18473023
32coenzyme catabolic process (GO:0009109)5.14293144
33phosphatidylethanolamine biosynthetic process (GO:0006646)5.13629602
34rRNA methylation (GO:0031167)5.13343670
35cell recognition (GO:0008037)5.00587853
36male meiosis I (GO:0007141)4.96960329
37glycerol ether metabolic process (GO:0006662)4.82133623
38ketone body metabolic process (GO:1902224)4.81147520
39phosphatidylethanolamine metabolic process (GO:0046337)4.79035987
40chromosome organization involved in meiosis (GO:0070192)4.71759476
41glomerular visceral epithelial cell development (GO:0072015)4.70596971
42multicellular organismal reproductive process (GO:0048609)4.69608032
43DNA methylation involved in gamete generation (GO:0043046)4.60735199
44microtubule severing (GO:0051013)4.60572621
45chromosome condensation (GO:0030261)4.57996715
46regulation of Rab GTPase activity (GO:0032313)4.50985930
47positive regulation of Rab GTPase activity (GO:0032851)4.50985930
48ether metabolic process (GO:0018904)4.46327360
49DNA packaging (GO:0006323)4.36802388
50meiotic nuclear division (GO:0007126)4.34989829
51seminiferous tubule development (GO:0072520)4.31866660
52glomerular epithelial cell development (GO:0072310)4.29360513
53protein localization to Golgi apparatus (GO:0034067)4.27515227
54left/right pattern formation (GO:0060972)4.26594449
55rRNA modification (GO:0000154)4.23826525
56gonadal mesoderm development (GO:0007506)4.20348277
57single strand break repair (GO:0000012)4.16365403
58meiosis I (GO:0007127)3.97672391
59chaperone-mediated protein complex assembly (GO:0051131)3.95222940
60sexual reproduction (GO:0019953)3.94359549
61regulation of establishment of cell polarity (GO:2000114)3.76159870
62multicellular organismal development (GO:0007275)3.74778616
63protein polyglutamylation (GO:0018095)3.67911257
64monoubiquitinated protein deubiquitination (GO:0035520)3.62144376
65genitalia morphogenesis (GO:0035112)3.60273643
66sex differentiation (GO:0007548)3.54589719
67detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.52988866
68microtubule polymerization or depolymerization (GO:0031109)3.39056913
69meiotic cell cycle (GO:0051321)3.35605135
70protein K11-linked deubiquitination (GO:0035871)3.35407427
71regulation of interleukin-13 production (GO:0032656)3.35368413
72musculoskeletal movement (GO:0050881)3.30366944
73multicellular organismal movement (GO:0050879)3.30366944
74regulation of spindle checkpoint (GO:0090231)3.29819687
75NAD biosynthetic process (GO:0009435)3.29105938
76tyrosine phosphorylation of STAT protein (GO:0007260)3.26666583
77protein refolding (GO:0042026)3.25811096
78nucleus organization (GO:0006997)3.18396351
79positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)3.17700295
80glycolytic process (GO:0006096)3.16827593
81opioid receptor signaling pathway (GO:0038003)3.16793379
82protein localization to cilium (GO:0061512)3.16535740
83negative regulation of cytosolic calcium ion concentration (GO:0051481)3.13293812
84axoneme assembly (GO:0035082)3.10540402
85cofactor catabolic process (GO:0051187)3.10044553
86left/right axis specification (GO:0070986)3.08263846
87sequestering of actin monomers (GO:0042989)3.08139924
88behavioral response to ethanol (GO:0048149)3.07963768
89centrosome duplication (GO:0051298)3.06756582
90antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.06729024
91chromatin silencing (GO:0006342)3.06417680
92regulation of transcription involved in cell fate commitment (GO:0060850)3.03616976
93regulation of establishment or maintenance of cell polarity (GO:0032878)3.03250879
94mitotic sister chromatid cohesion (GO:0007064)3.02880134
95nucleoside diphosphate phosphorylation (GO:0006165)3.00338599
96cilium organization (GO:0044782)2.99117939
97amino-acid betaine transport (GO:0015838)2.98103298
98carnitine transport (GO:0015879)2.98103298
99one-carbon compound transport (GO:0019755)2.97383015
100microtubule-based movement (GO:0007018)2.91280366
101intraciliary transport (GO:0042073)2.89557591
102meiotic cell cycle process (GO:1903046)2.89159198
103cilium assembly (GO:0042384)2.86884391
104pyridine nucleotide biosynthetic process (GO:0019363)2.86851545
105nicotinamide nucleotide biosynthetic process (GO:0019359)2.86851545
106polyol catabolic process (GO:0046174)2.84074019
107synapsis (GO:0007129)2.82682277
108carnitine transmembrane transport (GO:1902603)2.82274913
109interferon-gamma secretion (GO:0072643)2.80457620
110cellular component assembly involved in morphogenesis (GO:0010927)2.80086168
111centriole assembly (GO:0098534)2.80065402
112GTP biosynthetic process (GO:0006183)2.79260079
113RNA localization (GO:0006403)2.78365030
114alditol metabolic process (GO:0019400)2.78162727
115cilium morphogenesis (GO:0060271)2.75946311
116negative regulation of organelle assembly (GO:1902116)2.73042335
117positive regulation of macrophage activation (GO:0043032)2.68754009
118nuclear pore complex assembly (GO:0051292)2.67767079
119RNA destabilization (GO:0050779)2.67312276
120gene silencing by RNA (GO:0031047)2.60022933
121lactate metabolic process (GO:0006089)2.58603558
122regulation of centriole replication (GO:0046599)2.54871015
123UTP biosynthetic process (GO:0006228)2.52293172
124centriole replication (GO:0007099)2.51203243
125polyamine biosynthetic process (GO:0006596)2.51173088
126fusion of sperm to egg plasma membrane (GO:0007342)13.8289089
127sperm motility (GO:0030317)13.7831347
128cell wall macromolecule catabolic process (GO:0016998)12.8639530
129cell wall macromolecule metabolic process (GO:0044036)12.8639530
130acrosome reaction (GO:0007340)11.8620790
131sperm-egg recognition (GO:0035036)11.5104419
132acrosome assembly (GO:0001675)11.5015741
133multicellular organism reproduction (GO:0032504)11.2947564
134plasma membrane fusion (GO:0045026)10.5299797
135binding of sperm to zona pellucida (GO:0007339)10.3657772
136cell-cell recognition (GO:0009988)10.3007997
137cilium or flagellum-dependent cell motility (GO:0001539)10.1784365
138axonemal dynein complex assembly (GO:0070286)10.0958755
139epithelial cilium movement (GO:0003351)10.0842748

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.49586627
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.28909245
3EZH2_22144423_ChIP-Seq_EOC_Human3.60381854
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.40807791
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.03028511
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.91228411
7MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.82407243
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.62505443
9STAT6_21828071_ChIP-Seq_BEAS2B_Human2.60134520
10VDR_22108803_ChIP-Seq_LS180_Human2.54368466
11ER_23166858_ChIP-Seq_MCF-7_Human2.47609022
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.33704379
13CTBP1_25329375_ChIP-Seq_LNCAP_Human2.30722166
14GBX2_23144817_ChIP-Seq_PC3_Human2.29301122
15CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.25109633
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.14775381
17GATA1_26923725_Chip-Seq_HPCs_Mouse2.08253699
18UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human2.00115016
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.99739628
20ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.98197373
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.97645258
22PCGF2_27294783_Chip-Seq_ESCs_Mouse1.95301026
23SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.94496253
24KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.93488609
25DROSHA_22980978_ChIP-Seq_HELA_Human1.85646074
26P300_19829295_ChIP-Seq_ESCs_Human1.85163200
27ZNF274_21170338_ChIP-Seq_K562_Hela1.80561894
28TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.77807094
29STAT1_17558387_ChIP-Seq_HELA_Human1.75782472
30AR_25329375_ChIP-Seq_VCAP_Human1.73960035
31KAP1_22055183_ChIP-Seq_ESCs_Mouse1.71118043
32ELK4_26923725_Chip-Seq_MESODERM_Mouse1.67156675
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.66495322
34MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.66262726
35GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.62385646
36FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62141217
37STAT3_23295773_ChIP-Seq_U87_Human1.61721345
38WDR5_24793694_ChIP-Seq_LNCAP_Human1.61342744
39RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.60653515
40SMAD4_21741376_ChIP-Seq_EPCs_Human1.60247152
41SMAD3_21741376_ChIP-Seq_EPCs_Human1.58445228
42KDM2B_26808549_Chip-Seq_REH_Human1.54450796
43PCGF2_27294783_Chip-Seq_NPCs_Mouse1.53879654
44VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.53768217
45TAL1_26923725_Chip-Seq_HPCs_Mouse1.53591291
46GATA3_21867929_ChIP-Seq_CD8_Mouse1.51869499
47* SOX2_22085726_ChIP-Seq_NPCs_Mouse1.51734062
48ERA_21632823_ChIP-Seq_H3396_Human1.50906291
49* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49187477
50AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.47889990
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47453247
52RUNX2_22187159_ChIP-Seq_PCA_Human1.44377979
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.43386323
54AUTS2_25519132_ChIP-Seq_293T-REX_Human1.43382534
55TP53_18474530_ChIP-ChIP_U2OS_Human1.42782328
56CBP_20019798_ChIP-Seq_JUKART_Human1.42379786
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42379786
58SOX2_19829295_ChIP-Seq_ESCs_Human1.39656599
59NANOG_19829295_ChIP-Seq_ESCs_Human1.39656599
60KLF5_20875108_ChIP-Seq_MESCs_Mouse1.38193264
61* RBPJ_21746931_ChIP-Seq_IB4_Human1.37399700
62NANOG_20526341_ChIP-Seq_ESCs_Human1.37274881
63* ETV1_20927104_ChIP-Seq_GIST48_Human1.36174930
64* NFE2_27457419_Chip-Seq_LIVER_Mouse1.35317419
65LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.34930906
66TCF4_23295773_ChIP-Seq_U87_Human1.34338673
67* SMAD4_21799915_ChIP-Seq_A2780_Human1.33957150
68ARNT_22903824_ChIP-Seq_MCF-7_Human1.33326251
69* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.33221400
70GATA3_21867929_ChIP-Seq_TH1_Mouse1.32723983
71OCT4_20526341_ChIP-Seq_ESCs_Human1.31943063
72REST_21632747_ChIP-Seq_MESCs_Mouse1.31871737
73RAC3_21632823_ChIP-Seq_H3396_Human1.31169874
74* NFYB_21822215_ChIP-Seq_K562_Human1.30713501
75SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.30189744
76SALL1_21062744_ChIP-ChIP_HESCs_Human1.30126155
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29881834
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.29842443
79* CBX2_22325352_ChIP-Seq_293T-Rex_Human1.29699759
80FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.29039762
81FLI1_21867929_ChIP-Seq_TH2_Mouse1.28895643
82CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28336033
83PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.27295856
84P53_21459846_ChIP-Seq_SAOS-2_Human1.27085461
85ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.26846681
86TDRD3_21172665_ChIP-Seq_MCF-7_Human1.26712569
87* PHF8_20622853_ChIP-Seq_HELA_Human1.26555060
88SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25340601
89CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.25212159
90* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25059312
91FOXA1_21572438_ChIP-Seq_LNCaP_Human1.24065633
92* HNFA_21074721_ChIP-Seq_CACO-2_Human1.24019601
93* GATA3_21878914_ChIP-Seq_MCF-7_Human1.23544833
94* TBL1_22424771_ChIP-Seq_293T_Human1.22757553
95MYC_19829295_ChIP-Seq_ESCs_Human1.22425858
96TAF2_19829295_ChIP-Seq_ESCs_Human1.21888944
97SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.21750274
98FOXA1_27270436_Chip-Seq_PROSTATE_Human1.21740591
99FOXA1_25329375_ChIP-Seq_VCAP_Human1.21740591
100OCT1_27270436_Chip-Seq_PROSTATE_Human1.20251875
101ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20187194
102NR3C1_21868756_ChIP-Seq_MCF10A_Human1.19643797
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19503089
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19503089
105TCF4_18268006_ChIP-ChIP_LS174T_Human1.19207294
106EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.19146152
107TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.18404848
108NCOR_22424771_ChIP-Seq_293T_Human1.18302333
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17554733
110* NFYA_21822215_ChIP-Seq_K562_Human1.16780187
111GF1_26923725_Chip-Seq_HPCs_Mouse1.16677086
112ETV2_25802403_ChIP-Seq_MESCs_Mouse1.16214825
113PRDM14_20953172_ChIP-Seq_ESCs_Human1.15860487
114* PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.15495301
115CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15138231
116EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.14743601
117* NANOG_18555785_Chip-Seq_ESCs_Mouse1.13999363
118CEBPB_22108803_ChIP-Seq_LS180_Human1.13964095
119* CRX_20693478_ChIP-Seq_RETINA_Mouse1.13926416
120SPI1_26923725_Chip-Seq_HPCs_Mouse1.13531124
121TAF15_26573619_Chip-Seq_HEK293_Human1.13065718
122RAD21_21589869_ChIP-Seq_MESCs_Mouse1.12912086
123RNF2_27304074_Chip-Seq_NSC_Mouse1.12747955
124SMRT_27268052_Chip-Seq_Bcells_Human1.10983939
125RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.10843402
126HOXB7_26014856_ChIP-Seq_BT474_Human1.10412473
127FOXH1_21741376_ChIP-Seq_EPCs_Human1.10215447
128TCF4_22108803_ChIP-Seq_LS180_Human1.09979486
129CDX2_22108803_ChIP-Seq_LS180_Human1.08810102
130JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08355596
131* CJUN_26792858_Chip-Seq_BT549_Human1.08237258
132RUNX1_26923725_Chip-Seq_HPCs_Mouse1.07987464
133AR_21572438_ChIP-Seq_LNCaP_Human1.07663538
134PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07104622
135* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06495535
136FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.06213731
137PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06138595
138TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.05881331
139SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04935921
140* OCT4_18555785_Chip-Seq_ESCs_Mouse1.04617614
141EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.03479465
142ESET_19884257_ChIP-Seq_ESCs_Mouse1.03149809
143* P53_22387025_ChIP-Seq_ESCs_Mouse1.02670721
144FUS_26573619_Chip-Seq_HEK293_Human1.02655076
145RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.02636537
146* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02551523
147ERG_20517297_ChIP-Seq_VCAP_Human1.01721816
148* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.01637792
149* CMYC_18555785_Chip-Seq_ESCs_Mouse1.01565951
150STAT3_18555785_ChIP-Seq_MESCs_Mouse0.99821649
151YY1_22570637_ChIP-Seq_MALME-3M_Human0.98477530
152MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98308100
153* OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97819189
154RXRA_24833708_ChIP-Seq_LIVER_Mouse0.97785972
155* P300_18555785_Chip-Seq_ESCs_Mouse0.96555685
156RARA_24833708_ChIP-Seq_LIVER_Mouse0.96458748
157SOX9_26525672_Chip-Seq_HEART_Mouse0.95768557
158PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.95652953
159MYC_27129775_Chip-Seq_CORNEA_Mouse0.95606944
160* KLF4_18555785_Chip-Seq_ESCs_Mouse0.95565255
161* EZH2_27294783_Chip-Seq_NPCs_Mouse0.94882875
162LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.93368829
163GATA1_19941827_ChIP-Seq_MEL86_Mouse0.92428392
164CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.92400536
165* ESRRB_18555785_Chip-Seq_ESCs_Mouse0.91652403
166FLI1_21867929_ChIP-Seq_CD8_Mouse0.89853518
167SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.89766109
168GF1B_26923725_Chip-Seq_HPCs_Mouse0.89343349
169SOX11_22085726_ChIP-Seq_ESNs_Mouse0.89227562
170NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89157208
171* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88875928

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.07924665
2MP0001929_abnormal_gametogenesis5.50272765
3MP0008877_abnormal_DNA_methylation4.20156367
4MP0002210_abnormal_sex_determination3.46249886
5MP0002161_abnormal_fertility/fecundity3.33095260
6MP0001145_abnormal_male_reproductive2.95674484
7MP0005670_abnormal_white_adipose2.92326859
8MP0002653_abnormal_ependyma_morphology2.91005793
9MP0001968_abnormal_touch/_nociception2.67859888
10MP0001348_abnormal_lacrimal_gland2.58946506
11MP0000653_abnormal_sex_gland2.55190896
12MP0000678_abnormal_parathyroid_gland2.25268051
13MP0001485_abnormal_pinna_reflex2.13558135
14MP0001501_abnormal_sleep_pattern2.10005864
15MP0005410_abnormal_fertilization16.1088609
16MP0005623_abnormal_meninges_morphology1.93805002
17MP0003136_yellow_coat_color1.87482975
18MP0001486_abnormal_startle_reflex1.84223947
19MP0002132_abnormal_respiratory_system1.78295389
20MP0005310_abnormal_salivary_gland1.71241917
21MP0002160_abnormal_reproductive_system1.62261850
22MP0003646_muscle_fatigue1.57718420
23MP0009053_abnormal_anal_canal1.57129047
24MP0003718_maternal_effect1.56104519
25MP0002249_abnormal_larynx_morphology1.52643610
26MP0002282_abnormal_trachea_morphology1.43354249
27MP0001963_abnormal_hearing_physiology1.42725432
28MP0004233_abnormal_muscle_weight1.41899290
29MP0000230_abnormal_systemic_arterial1.27838993
30MP0003880_abnormal_central_pattern1.26188086
31MP0009745_abnormal_behavioral_response1.24491556
32MP0003252_abnormal_bile_duct1.20088016
33MP0008058_abnormal_DNA_repair1.20050539
34MP0005379_endocrine/exocrine_gland_phen1.18521733
35MP0002876_abnormal_thyroid_physiology1.13578881
36MP0000026_abnormal_inner_ear1.13458376
37MP0001765_abnormal_ion_homeostasis1.12364901
38MP0002138_abnormal_hepatobiliary_system1.12266334
39MP0006276_abnormal_autonomic_nervous1.12023696
40MP0000681_abnormal_thyroid_gland1.07269551
41MP0005248_abnormal_Harderian_gland1.06824875
42MP0009780_abnormal_chondrocyte_physiolo1.02153090
43MP0002733_abnormal_thermal_nociception1.01414194
44MP0009046_muscle_twitch1.01065977
45MP0001666_abnormal_nutrient_absorption1.00868249
46MP0008961_abnormal_basal_metabolism1.00120028
47MP0009384_cardiac_valve_regurgitation0.96292982
48MP0002127_abnormal_cardiovascular_syste0.94252808
49MP0003959_abnormal_lean_body0.93746027
50MP0008995_early_reproductive_senescence0.93379831
51MP0005085_abnormal_gallbladder_physiolo0.93272755
52MP0005647_abnormal_sex_gland0.92454269
53MP0001984_abnormal_olfaction0.92433878
54MP0004085_abnormal_heartbeat0.91537925
55MP0005395_other_phenotype0.85999033
56MP0010386_abnormal_urinary_bladder0.83847389
57MP0001970_abnormal_pain_threshold0.83842086
58MP0005266_abnormal_metabolism0.83197760
59MP0002067_abnormal_sensory_capabilities0.82593450
60MP0010094_abnormal_chromosome_stability0.81612340
61MP0005389_reproductive_system_phenotype0.80885167
62MP0003878_abnormal_ear_physiology0.76501027
63MP0005377_hearing/vestibular/ear_phenot0.76501027
64MP0005083_abnormal_biliary_tract0.75381474
65MP0002272_abnormal_nervous_system0.74460074
66MP0005332_abnormal_amino_acid0.74192113
67MP0003115_abnormal_respiratory_system0.73338917
68MP0003183_abnormal_peptide_metabolism0.72611087
69MP0008057_abnormal_DNA_replication0.69627626
70MP0002557_abnormal_social/conspecific_i0.69614246
71MP0002234_abnormal_pharynx_morphology0.69323171
72MP0005646_abnormal_pituitary_gland0.69044651
73MP0002735_abnormal_chemical_nociception0.67109939
74MP0005171_absent_coat_pigmentation0.66555925
75MP0001293_anophthalmia0.66529118
76MP0008872_abnormal_physiological_respon0.65572077
77MP0001664_abnormal_digestion0.64742300
78MP0003111_abnormal_nucleus_morphology0.64244197
79MP0002139_abnormal_hepatobiliary_system0.62939257
80MP0003011_delayed_dark_adaptation0.61539253
81MP0010329_abnormal_lipoprotein_level0.60930749
82MP0005666_abnormal_adipose_tissue0.60011661
83MP0002102_abnormal_ear_morphology0.58901193
84MP0005503_abnormal_tendon_morphology0.57714339
85MP0005595_abnormal_vascular_smooth0.56721211
86MP0005360_urolithiasis0.55887923
87MP0003638_abnormal_response/metabolism_0.55883219
88MP0003137_abnormal_impulse_conducting0.55797942
89MP0002108_abnormal_muscle_morphology0.55699176
90MP0001905_abnormal_dopamine_level0.55187690
91MP0003699_abnormal_female_reproductive0.53510269
92MP0009764_decreased_sensitivity_to0.53436412
93MP0000427_abnormal_hair_cycle0.53376034
94MP0005636_abnormal_mineral_homeostasis0.53110213
95MP0005551_abnormal_eye_electrophysiolog0.51245466
96MP0000358_abnormal_cell_content/0.48301403
97MP0002928_abnormal_bile_duct0.48142376
98MP0003950_abnormal_plasma_membrane0.48041419
99MP0002269_muscular_atrophy0.47943850
100MP0001324_abnormal_eye_pigmentation0.47673031
101MP0004036_abnormal_muscle_relaxation0.47428816
102MP0005253_abnormal_eye_physiology0.46249959
103MP0004133_heterotaxia0.44053603
104MP0003786_premature_aging0.42505529
105MP0003329_amyloid_beta_deposits0.40862292
106MP0001764_abnormal_homeostasis0.39800642
107MP0005391_vision/eye_phenotype0.38362879
108MP0000534_abnormal_ureter_morphology0.37867657
109MP0009115_abnormal_fat_cell0.36814291
110MP0001119_abnormal_female_reproductive0.36730524
111MP0001730_embryonic_growth_arrest0.34649210
112MP0003283_abnormal_digestive_organ0.34306472
113MP0003861_abnormal_nervous_system0.34275104
114MP0004019_abnormal_vitamin_homeostasis0.32296679
115MP0006036_abnormal_mitochondrial_physio0.32124290
116MP0002971_abnormal_brown_adipose0.31092724
117MP0001545_abnormal_hematopoietic_system0.30244470
118MP0005397_hematopoietic_system_phenotyp0.30244470
119MP0009278_abnormal_bone_marrow0.29767204
120MP0001727_abnormal_embryo_implantation0.28669737
121MP0002084_abnormal_developmental_patter0.28556363
122MP0008007_abnormal_cellular_replicative0.27934765
123MP0002152_abnormal_brain_morphology0.27452504
124MP0002736_abnormal_nociception_after0.27256668
125MP0010307_abnormal_tumor_latency0.26656756
126MP0003633_abnormal_nervous_system0.25719003
127MP0003948_abnormal_gas_homeostasis0.25058307
128MP0003787_abnormal_imprinting0.23913990
129MP0006035_abnormal_mitochondrial_morpho0.23786753
130MP0002092_abnormal_eye_morphology0.23544894
131MP0006072_abnormal_retinal_apoptosis0.23383831
132MP0003077_abnormal_cell_cycle0.22983898
133MP0003942_abnormal_urinary_system0.22918358
134MP0001661_extended_life_span0.21757602
135MP0001986_abnormal_taste_sensitivity0.21575744
136MP0000569_abnormal_digit_pigmentation0.21211638
137MP0002169_no_abnormal_phenotype0.20977230
138MP0002873_normal_phenotype0.20633457
139MP0005380_embryogenesis_phenotype0.20320565
140MP0001672_abnormal_embryogenesis/_devel0.20320565
141MP0003879_abnormal_hair_cell0.20267650
142MP0000313_abnormal_cell_death0.20235006
143MP0002295_abnormal_pulmonary_circulatio0.20097830
144MP0004811_abnormal_neuron_physiology0.20080376
145MP0003631_nervous_system_phenotype0.19567888
146MP0004270_analgesia0.19320032
147MP0004742_abnormal_vestibular_system0.19039939
148MP0002085_abnormal_embryonic_tissue0.18290497
149MP0001440_abnormal_grooming_behavior0.17747028
150MP0001697_abnormal_embryo_size0.17652014
151MP0005195_abnormal_posterior_eye0.17551246
152MP0005423_abnormal_somatic_nervous0.17175475
153MP0003936_abnormal_reproductive_system0.16850361
154MP0000462_abnormal_digestive_system0.15888416
155MP0000432_abnormal_head_morphology0.15467255
156MP0004145_abnormal_muscle_electrophysio0.15400464
157MP0000604_amyloidosis0.15164760
158MP0002229_neurodegeneration0.14940639
159MP0000751_myopathy0.14748429

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.50731658
2Abnormal respiratory motile cilium morphology (HP:0005938)9.37684578
3Abnormal respiratory epithelium morphology (HP:0012253)9.37684578
4Severe visual impairment (HP:0001141)8.32113936
5Abnormal ciliary motility (HP:0012262)7.80979503
6Rhinitis (HP:0012384)7.58411195
7Chronic bronchitis (HP:0004469)7.04560233
8Infertility (HP:0000789)6.55395857
9Nasal polyposis (HP:0100582)6.12337933
10Abnormality of the nasal mucosa (HP:0000433)5.00283956
11Attenuation of retinal blood vessels (HP:0007843)4.91755400
12Male infertility (HP:0003251)4.79634935
13Bony spicule pigmentary retinopathy (HP:0007737)4.63036780
14Genetic anticipation (HP:0003743)4.49962913
15Bronchiectasis (HP:0002110)4.48792184
16Bronchitis (HP:0012387)4.48600714
17Progressive cerebellar ataxia (HP:0002073)4.42966594
18Nephronophthisis (HP:0000090)4.41151921
19Chronic hepatic failure (HP:0100626)4.12699786
20Abnormality of macular pigmentation (HP:0008002)4.01937425
21Abnormal spermatogenesis (HP:0008669)3.71709068
22Recurrent sinusitis (HP:0011108)3.51176380
23Hypoplastic ischia (HP:0003175)3.33517244
24Abnormality of the renal medulla (HP:0100957)3.30797501
25Recurrent otitis media (HP:0000403)3.23852074
26Gaze-evoked nystagmus (HP:0000640)3.14751721
27Congenital sensorineural hearing impairment (HP:0008527)3.02979313
28Postural instability (HP:0002172)3.00542297
29Hyperkalemia (HP:0002153)2.99727494
30Abnormality of the ischium (HP:0003174)2.97832232
31Tubulointerstitial nephritis (HP:0001970)2.97690269
32Abnormal rod and cone electroretinograms (HP:0008323)2.95767773
33Prostate neoplasm (HP:0100787)2.87235103
34Potter facies (HP:0002009)2.82620650
35Facial shape deformation (HP:0011334)2.82620650
36Enlarged epiphyses (HP:0010580)2.81893639
37Impulsivity (HP:0100710)2.81374812
38Pendular nystagmus (HP:0012043)2.80958488
39Recurrent bronchitis (HP:0002837)2.77961035
40Molar tooth sign on MRI (HP:0002419)2.70522232
41Abnormality of midbrain morphology (HP:0002418)2.70522232
42Cone-rod dystrophy (HP:0000548)2.67632291
43Aplasia/Hypoplasia of the earlobes (HP:0009906)2.66510368
44Polyuria (HP:0000103)2.61106025
45Pancreatic cysts (HP:0001737)2.60883849
46Slow saccadic eye movements (HP:0000514)2.59980785
47Thyroid-stimulating hormone excess (HP:0002925)2.56122193
48Tubular atrophy (HP:0000092)2.53725740
49Abnormality of the hepatic vasculature (HP:0006707)2.47454244
50Abnormality of dental color (HP:0011073)2.43516648
51Keratoconus (HP:0000563)2.42577048
52Increased corneal curvature (HP:0100692)2.42577048
53Medial flaring of the eyebrow (HP:0010747)2.41737717
54Recurrent corneal erosions (HP:0000495)2.41653521
55Tubulointerstitial abnormality (HP:0001969)2.40378512
56Azoospermia (HP:0000027)2.38447893
57Gonadotropin excess (HP:0000837)2.29658935
58Abnormality of the aortic arch (HP:0012303)2.28459358
59Osteomalacia (HP:0002749)2.25691611
60Amblyopia (HP:0000646)2.22444130
61Abolished electroretinogram (ERG) (HP:0000550)2.18587188
62Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.16283813
63Amelogenesis imperfecta (HP:0000705)2.15400152
64Abnormal gallbladder physiology (HP:0012438)2.14556611
65Cholecystitis (HP:0001082)2.14556611
66Resting tremor (HP:0002322)2.10395288
67Action tremor (HP:0002345)2.10229967
68Menstrual irregularities (HP:0000858)2.06850332
69Unilateral renal agenesis (HP:0000122)2.05864393
70Abnormality of potassium homeostasis (HP:0011042)2.04601538
71Generalized aminoaciduria (HP:0002909)2.03366403
72Sclerocornea (HP:0000647)2.01062503
73Dyschromatopsia (HP:0007641)2.00936441
74Spastic paraparesis (HP:0002313)2.00869041
75Dynein arm defect of respiratory motile cilia (HP:0012255)13.2251395
76Absent/shortened dynein arms (HP:0200106)13.2251395
77Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1145238
78Abnormal albumin level (HP:0012116)1.99420359
79Hypoalbuminemia (HP:0003073)1.99420359
80Postaxial foot polydactyly (HP:0001830)1.96804069
81Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.93716081
82Portal hypertension (HP:0001409)1.91295720
83Scotoma (HP:0000575)1.90763098
84Decreased central vision (HP:0007663)1.87826079
85Photophobia (HP:0000613)1.86037804
86Macular degeneration (HP:0000608)1.84876682
87Spastic tetraparesis (HP:0001285)1.84280071
88Stage 5 chronic kidney disease (HP:0003774)1.83431508
89Large for gestational age (HP:0001520)1.83326545
90Retinitis pigmentosa (HP:0000510)1.82129903
91Tubulointerstitial fibrosis (HP:0005576)1.81697856
92Abnormality of dentin (HP:0010299)1.81450112
93Cerebellar dysplasia (HP:0007033)1.81108791
94Congenital hepatic fibrosis (HP:0002612)1.80852051
95Dysmetric saccades (HP:0000641)1.80396794
96Heterotopia (HP:0002282)1.79814196
97Spontaneous abortion (HP:0005268)1.78464697
98Choroideremia (HP:0001139)1.77916285
99Type II lissencephaly (HP:0007260)1.74985596
100Short ribs (HP:0000773)1.74854569
101Pigmentary retinal degeneration (HP:0001146)1.74446567
102Hypoplasia of the thymus (HP:0000778)1.73626366
103Abnormality of the ileum (HP:0001549)1.73109778
104Hypophosphatemic rickets (HP:0004912)1.72682666
105Abnormality of the lower motor neuron (HP:0002366)1.68380840
106Polydipsia (HP:0001959)1.68057684
107Abnormal drinking behavior (HP:0030082)1.68057684
108Bile duct proliferation (HP:0001408)1.65937977
109Abnormal biliary tract physiology (HP:0012439)1.65937977
110Abnormality of the dental pulp (HP:0006479)1.65315962
111Abnormality of the renal cortex (HP:0011035)1.64632795
112Abnormality of permanent molar morphology (HP:0011071)1.64424190
113Abnormality of the dental root (HP:0006486)1.64424190
114Taurodontia (HP:0000679)1.64424190
115Abnormality of renal excretion (HP:0011036)1.59502978
116Bell-shaped thorax (HP:0001591)1.58879081
117Oculomotor apraxia (HP:0000657)1.57976042
118Abnormality of molar (HP:0011077)1.54179959
119Abnormality of molar morphology (HP:0011070)1.54179959
120Hypoplasia of the capital femoral epiphysis (HP:0003090)1.52126933
121Postaxial hand polydactyly (HP:0001162)1.50834816
122Pancreatic fibrosis (HP:0100732)1.50745140
123Facial cleft (HP:0002006)1.50328486
124Hemiparesis (HP:0001269)1.46797827
125Renal dysplasia (HP:0000110)1.43574253
126Aplasia/Hypoplasia of the lens (HP:0008063)1.43331729
127Fibular hypoplasia (HP:0003038)1.42228525
128Cystic liver disease (HP:0006706)1.41806961
129Microglossia (HP:0000171)1.41620292
130Hemorrhage of the eye (HP:0011885)1.40209676
131Asymmetric septal hypertrophy (HP:0001670)1.39652309
132Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.39539183
133Median cleft lip (HP:0000161)1.37301199
134Supernumerary spleens (HP:0009799)1.34797557
135Chronic sinusitis (HP:0011109)1.34220994
136Congenital primary aphakia (HP:0007707)1.33547643
137Gait imbalance (HP:0002141)1.32826476
138Abnormal urine output (HP:0012590)1.31167023
139Congenital malformation of the right heart (HP:0011723)1.29822044
140Double outlet right ventricle (HP:0001719)1.29822044
141Aplasia/Hypoplasia of the tongue (HP:0010295)1.29565030
142Bundle branch block (HP:0011710)1.29477192
143Amyotrophic lateral sclerosis (HP:0007354)1.25996774
144Decreased electroretinogram (ERG) amplitude (HP:0000654)1.25241300
145Absent frontal sinuses (HP:0002688)1.24850787
146True hermaphroditism (HP:0010459)1.24634071
147Deformed sella turcica (HP:0002681)1.23127895
148Neurofibrillary tangles (HP:0002185)1.21139449
149Short thorax (HP:0010306)1.20875636
150Optic nerve hypoplasia (HP:0000609)1.20868817
151Nephropathy (HP:0000112)1.20183530
152Abnormality of abdominal situs (HP:0011620)1.18405985
153Abdominal situs inversus (HP:0003363)1.18405985
154Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.17143647
155Absent epiphyses (HP:0010577)1.17143647
156Truncal obesity (HP:0001956)1.16446049
157Broad distal phalanx of finger (HP:0009836)1.15595988
158Abnormality of ocular smooth pursuit (HP:0000617)1.15381525
159Sensory axonal neuropathy (HP:0003390)1.15151307
160Easy fatigability (HP:0003388)1.13251821
161J-shaped sella turcica (HP:0002680)1.13207883

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.43977911
2PDK48.43977911
3TESK15.70483368
4PDK25.47070302
5FRK5.33251223
6PRKD35.00682351
7ICK4.25556978
8INSRR4.17285259
9DDR23.40661892
10MAP4K23.20457004
11ADRBK23.12729771
12BMPR1B3.05493875
13CDK192.91057293
14PLK22.82972036
15ACVR1B2.57316686
16PNCK2.23296599
17PTK2B2.16031087
18WNK42.04140390
19PIK3CG1.97839277
20STK391.92805201
21LATS11.76542198
22EIF2AK31.73545898
23STK381.68119107
24OXSR11.64327932
25BRD41.58033959
26NEK21.55819316
27DYRK1B1.40495671
28MAP3K41.25329543
29DYRK31.08168201
30PDK11.07056608
31NUAK11.02957420
32MST1R1.02906910
33TGFBR10.97973935
34TYRO30.94188902
35TTK0.90764878
36GRK10.86953764
37MAPK150.83694535
38BCKDK0.81127773
39WNK10.78866436
40CHEK20.76567823
41MAP3K60.75533584
42ADRBK10.74654513
43MYLK0.73285486
44MAP3K70.72694896
45TNK20.72512008
46PASK0.71244840
47IRAK10.65652775
48CDK70.63126805
49WEE10.62301981
50PRKCE0.62158462
51PRKAA20.61954359
52MAP3K120.61210855
53MAP2K60.59623266
54STK30.58289186
55PINK10.57791420
56TXK0.57433906
57KSR20.56968828
58TESK20.56623849
59PDPK10.56100295
60CAMK1G0.55537553
61CCNB10.54265090
62LMTK20.53396164
63PLK40.52014432
64CDK80.52013754
65TIE10.51335035
66NEK90.49505673
67CHEK10.46623434
68MAPK110.45931496
69EEF2K0.45302781
70PAK10.45070465
71RIPK40.44837771
72STK38L0.44735946
73MUSK0.42777591
74CDK120.42578813
75CDC70.42012311
76CAMK10.38767035
77FER0.37960984
78LIMK10.36610185
79EPHA30.36202806
80ATR0.35968767
81NTRK20.35875654
82MAP2K10.34790873
83PAK20.34623840
84ATM0.34465087
85IRAK20.34353242
86MAPK130.34022359
87PRKCG0.32781547
88PLK10.31391393
89NEK60.30586161
90MTOR0.30250326
91ZAK0.29733430
92CAMKK20.29151387
93ROCK10.29139861
94BMX0.28472997
95MAPK10.28361119
96MKNK20.27654820
97MAP2K20.25632419
98GRK70.24770713
99SIK20.23210555
100PRKAA10.23207535
101MAP3K20.23019605
102IGF1R0.22094820
103PRKACB0.21216072
104CDK40.18636900
105DAPK10.18210856
106PAK40.17724887
107MAPKAPK30.17560389
108BRSK20.17028335
109OBSCN0.16228210
110MAP3K100.16176105
111KDR0.15977429
112PAK30.15599307
113NTRK30.15029162
114MARK20.14883202
115PRKCZ0.13028017
116RPS6KB10.12753863
117CDK60.12087598
118GSK3B0.11933856
119BRSK10.11731217
120CDK20.10911674
121CSNK2A10.10640817
122CDK150.09244802
123CDK10.08862898
124CSNK1D0.08755761
125CAMKK10.08455951
126CSNK2A20.07554008
127AURKA0.07530706
128WNK30.07512247
129PRKCQ0.06863451
130CDK11A0.06660124
131CDK180.06635535
132PRKG20.06327845
133MAPKAPK50.06253362
134CDK30.04409508
135PRKG10.04328830
136STK100.04217555
137MARK30.04142185
138RPS6KA10.04085757
139STK110.04063341
140BRAF0.03122688
141MARK10.02841987
142PAK60.02824472
143MAPK80.02666072
144PRKACG0.02650551
145CAMK2A0.02617697
146CDK140.02487088
147PRKDC0.02264534
148STK160.02077290
149PRKCB0.01816037
150MAPK100.01774863
151PKN10.01464778
152CSNK1E0.01090402
153ZAP700.00624993
154PIM10.00557735
155AKT3-0.0100979
156RIPK1-0.0089248
157PRKCA-0.0083046
158YES1-0.0062428
159PRKACA-0.0041046

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.66364335
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.43130628
3Fatty acid biosynthesis_Homo sapiens_hsa000614.21340302
4Primary bile acid biosynthesis_Homo sapiens_hsa001203.77915084
5Vitamin B6 metabolism_Homo sapiens_hsa007503.75909539
6Olfactory transduction_Homo sapiens_hsa047403.67361303
7Butanoate metabolism_Homo sapiens_hsa006503.37401514
8Pyruvate metabolism_Homo sapiens_hsa006203.23773286
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.06730658
10Linoleic acid metabolism_Homo sapiens_hsa005913.00223173
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.63260201
12Propanoate metabolism_Homo sapiens_hsa006402.55546083
13Glucagon signaling pathway_Homo sapiens_hsa049222.44297206
14Basal transcription factors_Homo sapiens_hsa030222.43673537
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.39848964
16Carbohydrate digestion and absorption_Homo sapiens_hsa049732.20169160
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.04756839
18Steroid hormone biosynthesis_Homo sapiens_hsa001401.98718329
19Selenocompound metabolism_Homo sapiens_hsa004501.97842034
20Fanconi anemia pathway_Homo sapiens_hsa034601.96534332
21Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.90861669
22Glycerolipid metabolism_Homo sapiens_hsa005611.89960522
23Oocyte meiosis_Homo sapiens_hsa041141.87690275
24Pentose phosphate pathway_Homo sapiens_hsa000301.85151468
25Tryptophan metabolism_Homo sapiens_hsa003801.81604753
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.78064480
27Caffeine metabolism_Homo sapiens_hsa002321.77646020
28Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.77253140
29PPAR signaling pathway_Homo sapiens_hsa033201.76333453
30Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.72790638
31Phototransduction_Homo sapiens_hsa047441.71470473
32Glycerophospholipid metabolism_Homo sapiens_hsa005641.70811650
33Retinol metabolism_Homo sapiens_hsa008301.69906767
34Dorso-ventral axis formation_Homo sapiens_hsa043201.67949961
35Fructose and mannose metabolism_Homo sapiens_hsa000511.63592210
36Mineral absorption_Homo sapiens_hsa049781.63259130
37Glycosaminoglycan degradation_Homo sapiens_hsa005311.61259536
38Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.49559331
39Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.48463866
40Carbon metabolism_Homo sapiens_hsa012001.44362041
41Ether lipid metabolism_Homo sapiens_hsa005651.40885723
42Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.37801281
43Amphetamine addiction_Homo sapiens_hsa050311.35821213
44Cardiac muscle contraction_Homo sapiens_hsa042601.33181875
45Fat digestion and absorption_Homo sapiens_hsa049751.29312042
46Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.29001709
47mRNA surveillance pathway_Homo sapiens_hsa030151.28223267
48RNA transport_Homo sapiens_hsa030131.26557969
49Morphine addiction_Homo sapiens_hsa050321.20350315
50Huntingtons disease_Homo sapiens_hsa050161.20237559
51Cysteine and methionine metabolism_Homo sapiens_hsa002701.15335772
52Purine metabolism_Homo sapiens_hsa002301.14002967
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.12103293
54Antigen processing and presentation_Homo sapiens_hsa046121.11900083
55Fatty acid metabolism_Homo sapiens_hsa012121.10248306
56Fatty acid degradation_Homo sapiens_hsa000711.10044337
57Renin secretion_Homo sapiens_hsa049241.07531690
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05528370
59Biosynthesis of amino acids_Homo sapiens_hsa012301.03687018
60Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00861006
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.99371946
62Graft-versus-host disease_Homo sapiens_hsa053320.96169527
63Glutathione metabolism_Homo sapiens_hsa004800.95914966
64Nicotine addiction_Homo sapiens_hsa050330.94919072
65Hedgehog signaling pathway_Homo sapiens_hsa043400.90735258
66Sulfur relay system_Homo sapiens_hsa041220.90465254
67Arachidonic acid metabolism_Homo sapiens_hsa005900.87796661
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.82674144
69Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81570284
70beta-Alanine metabolism_Homo sapiens_hsa004100.80597749
71Nitrogen metabolism_Homo sapiens_hsa009100.80284928
72Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79737426
73Glutamatergic synapse_Homo sapiens_hsa047240.79343725
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.79017186
75Histidine metabolism_Homo sapiens_hsa003400.76329186
76Insulin secretion_Homo sapiens_hsa049110.76317077
77Arginine and proline metabolism_Homo sapiens_hsa003300.72279807
78Renin-angiotensin system_Homo sapiens_hsa046140.72127301
79Bile secretion_Homo sapiens_hsa049760.71918143
80Thyroid hormone synthesis_Homo sapiens_hsa049180.71809688
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71805866
82Autoimmune thyroid disease_Homo sapiens_hsa053200.71692482
83Peroxisome_Homo sapiens_hsa041460.70523854
84Estrogen signaling pathway_Homo sapiens_hsa049150.68335852
85Collecting duct acid secretion_Homo sapiens_hsa049660.67058925
86Circadian rhythm_Homo sapiens_hsa047100.66134564
87cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64292767
88Chemical carcinogenesis_Homo sapiens_hsa052040.62452425
89Serotonergic synapse_Homo sapiens_hsa047260.61921904
90Calcium signaling pathway_Homo sapiens_hsa040200.61651359
91Allograft rejection_Homo sapiens_hsa053300.61532932
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.59671525
93Long-term potentiation_Homo sapiens_hsa047200.59106676
94Salivary secretion_Homo sapiens_hsa049700.57516211
95Protein digestion and absorption_Homo sapiens_hsa049740.56736064
96Systemic lupus erythematosus_Homo sapiens_hsa053220.55774594
97Taste transduction_Homo sapiens_hsa047420.55217505
98Pancreatic secretion_Homo sapiens_hsa049720.54418618
99Central carbon metabolism in cancer_Homo sapiens_hsa052300.53839540
100Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52447753
101Inositol phosphate metabolism_Homo sapiens_hsa005620.51652483
102Legionellosis_Homo sapiens_hsa051340.50758542
103Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.50252484
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47958852
105Pyrimidine metabolism_Homo sapiens_hsa002400.47761433
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47555268
107Starch and sucrose metabolism_Homo sapiens_hsa005000.46076769
108Sphingolipid metabolism_Homo sapiens_hsa006000.44785921
109ABC transporters_Homo sapiens_hsa020100.44473767
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43439099
111Metabolic pathways_Homo sapiens_hsa011000.42656086
112Ovarian steroidogenesis_Homo sapiens_hsa049130.40822445
113Vascular smooth muscle contraction_Homo sapiens_hsa042700.39817067
114Melanoma_Homo sapiens_hsa052180.39657540
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39320323
116Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.38779331
117AMPK signaling pathway_Homo sapiens_hsa041520.37104973
118Endocytosis_Homo sapiens_hsa041440.36707893
119cAMP signaling pathway_Homo sapiens_hsa040240.35598704
120Type I diabetes mellitus_Homo sapiens_hsa049400.35501321
121Gastric acid secretion_Homo sapiens_hsa049710.34566634
122Type II diabetes mellitus_Homo sapiens_hsa049300.34410692
123Non-homologous end-joining_Homo sapiens_hsa034500.34343282
124MAPK signaling pathway_Homo sapiens_hsa040100.33299438
125Cell cycle_Homo sapiens_hsa041100.33183477
126ECM-receptor interaction_Homo sapiens_hsa045120.32869756
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31989694
128Circadian entrainment_Homo sapiens_hsa047130.31573303
129Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31328551
130Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.30926293
131Oxytocin signaling pathway_Homo sapiens_hsa049210.30349214
132Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.30159661
133RNA degradation_Homo sapiens_hsa030180.29327550
134Synaptic vesicle cycle_Homo sapiens_hsa047210.29280027
135Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.29244531
136DNA replication_Homo sapiens_hsa030300.26271644
137Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26207375
138Drug metabolism - other enzymes_Homo sapiens_hsa009830.26167086
139Tyrosine metabolism_Homo sapiens_hsa003500.25920222
140Homologous recombination_Homo sapiens_hsa034400.21926447
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.20472978
142Alcoholism_Homo sapiens_hsa050340.18680438
143Basal cell carcinoma_Homo sapiens_hsa052170.16820814
144Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.15348599
145Wnt signaling pathway_Homo sapiens_hsa043100.14461809
146VEGF signaling pathway_Homo sapiens_hsa043700.13175539
147Cocaine addiction_Homo sapiens_hsa050300.10432671
148Sulfur metabolism_Homo sapiens_hsa009200.08434548
149Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.08207966
150Viral carcinogenesis_Homo sapiens_hsa052030.05720525

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