WDR7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.91607087
2synaptic vesicle maturation (GO:0016188)5.61284681
3locomotory exploration behavior (GO:0035641)5.22222016
4synaptic vesicle exocytosis (GO:0016079)5.18778563
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.16021746
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.98853934
7glutamate secretion (GO:0014047)4.94735531
8vocalization behavior (GO:0071625)4.85861496
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.78296820
10regulation of synaptic vesicle exocytosis (GO:2000300)4.72554921
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.48490180
12regulation of glutamate receptor signaling pathway (GO:1900449)4.47716653
13protein localization to synapse (GO:0035418)4.42852539
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.33476117
15neuron cell-cell adhesion (GO:0007158)4.29917456
16regulation of synaptic vesicle transport (GO:1902803)4.24071310
17exploration behavior (GO:0035640)4.19918953
18neurotransmitter secretion (GO:0007269)4.12363217
19layer formation in cerebral cortex (GO:0021819)4.06208599
20regulation of neuronal synaptic plasticity (GO:0048168)4.02811279
21regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.00067050
22regulation of long-term neuronal synaptic plasticity (GO:0048169)3.98952337
23regulation of synapse structural plasticity (GO:0051823)3.96931144
24neuronal action potential propagation (GO:0019227)3.95870596
25cellular potassium ion homeostasis (GO:0030007)3.93417439
26glutamate receptor signaling pathway (GO:0007215)3.85682267
27neuron recognition (GO:0008038)3.82449769
28proline transport (GO:0015824)3.80107641
29synaptic transmission, glutamatergic (GO:0035249)3.78288017
30membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.66630887
31neuron-neuron synaptic transmission (GO:0007270)3.64562818
32synaptic vesicle endocytosis (GO:0048488)3.61499995
33dendritic spine morphogenesis (GO:0060997)3.61077909
34gamma-aminobutyric acid transport (GO:0015812)3.60007128
35neurotransmitter-gated ion channel clustering (GO:0072578)3.56976031
36activation of protein kinase A activity (GO:0034199)3.54710857
37cerebellar Purkinje cell differentiation (GO:0021702)3.53477567
38regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.50678040
39regulation of excitatory postsynaptic membrane potential (GO:0060079)3.49660953
40sodium ion export (GO:0071436)3.49140169
41positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.41022635
42regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.41022635
43long-term memory (GO:0007616)3.38856909
44regulation of interleukin-12 biosynthetic process (GO:0045075)3.38072819
45vesicle transport along microtubule (GO:0047496)3.37853074
46regulation of postsynaptic membrane potential (GO:0060078)3.37586003
47neurotransmitter transport (GO:0006836)3.37315092
48axonal fasciculation (GO:0007413)3.36973483
49positive regulation of synapse maturation (GO:0090129)3.36264249
50dendrite morphogenesis (GO:0048813)3.31982255
51regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.30080462
52positive regulation of membrane potential (GO:0045838)3.29171299
53regulation of synaptic plasticity (GO:0048167)3.28182128
54response to pheromone (GO:0019236)3.24601060
55cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.23506867
56regulation of ARF protein signal transduction (GO:0032012)3.20824258
57regulation of neurotransmitter secretion (GO:0046928)3.20450389
58neuromuscular process controlling balance (GO:0050885)3.20123830
59membrane depolarization during action potential (GO:0086010)3.19702265
60negative regulation of interleukin-17 production (GO:0032700)3.18835792
61long-term synaptic potentiation (GO:0060291)3.17374779
62innervation (GO:0060384)3.17078432
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.15938229
64neuromuscular process controlling posture (GO:0050884)3.15466562
65regulation of dendritic spine morphogenesis (GO:0061001)3.14357584
66positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.14130460
67gamma-aminobutyric acid signaling pathway (GO:0007214)3.11916053
68positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.11529261
69regulation of neurotransmitter levels (GO:0001505)3.09719157
70transmission of nerve impulse (GO:0019226)3.05721033
71cell communication by electrical coupling (GO:0010644)3.05423012
72organelle transport along microtubule (GO:0072384)3.05323266
73negative regulation of neurotransmitter transport (GO:0051589)3.04466172
74regulation of isotype switching to IgG isotypes (GO:0048302)3.04102307
75nerve growth factor signaling pathway (GO:0038180)3.03969649
76positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.02402375
77regulation of vesicle fusion (GO:0031338)3.00965020
78response to auditory stimulus (GO:0010996)3.00113235
79potassium ion import (GO:0010107)2.98795265
80membrane depolarization (GO:0051899)2.98683017
81negative regulation of cytosolic calcium ion concentration (GO:0051481)2.95761062
82membrane hyperpolarization (GO:0060081)2.95461601
83retinal cone cell development (GO:0046549)2.95040425
84negative regulation of synaptic transmission, GABAergic (GO:0032229)2.93357614
85positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.92746372
86glycine transport (GO:0015816)2.91929302
87regulation of neurotransmitter transport (GO:0051588)2.91553898
88mating behavior (GO:0007617)2.91485687
89behavioral fear response (GO:0001662)2.90512178
90behavioral defense response (GO:0002209)2.90512178
91neurotransmitter uptake (GO:0001504)2.88762486
92G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.87635643
93negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.86889000
94L-amino acid import (GO:0043092)2.85966402
95prepulse inhibition (GO:0060134)2.85151805
96synapse assembly (GO:0007416)2.85108354
97cell migration in hindbrain (GO:0021535)2.84702286
98response to histamine (GO:0034776)2.84459361
99positive regulation of synaptic transmission, GABAergic (GO:0032230)2.84162547
100auditory behavior (GO:0031223)2.82485069
101neuromuscular process (GO:0050905)2.81813839
102positive regulation of neurotransmitter secretion (GO:0001956)2.81762031
103detection of calcium ion (GO:0005513)2.81131516
104learning (GO:0007612)2.80369250
105positive regulation of neurotransmitter transport (GO:0051590)2.79760884
106cellular response to ethanol (GO:0071361)2.79679140
107regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.78542887
108regulation of dendritic spine development (GO:0060998)2.77806013
109positive regulation of synaptic transmission (GO:0050806)2.77267235
110postsynaptic membrane organization (GO:0001941)2.77135359
111G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.77135132
112intraspecies interaction between organisms (GO:0051703)2.76468257
113social behavior (GO:0035176)2.76468257
114Golgi to endosome transport (GO:0006895)2.76142242
115fear response (GO:0042596)2.75108426
116regulation of synaptic transmission (GO:0050804)2.75084958
117positive regulation of phosphatase activity (GO:0010922)2.74439984
118regulation of voltage-gated calcium channel activity (GO:1901385)2.74436614
119neuronal ion channel clustering (GO:0045161)2.70696729
120regulation of calcium ion-dependent exocytosis (GO:0017158)2.69653674
121negative regulation of neurotransmitter secretion (GO:0046929)2.68594763
122cerebellar granule cell differentiation (GO:0021707)2.67346959
123positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.65156419
124regulation of MHC class II biosynthetic process (GO:0045346)2.64938868
125adult walking behavior (GO:0007628)2.61627922
126regulation of cell communication by electrical coupling (GO:0010649)2.61394292
127cell differentiation in hindbrain (GO:0021533)2.59500412
128startle response (GO:0001964)2.58353575
129presynaptic membrane assembly (GO:0097105)2.58334123
130amino acid import (GO:0043090)2.57979246
131presynaptic membrane organization (GO:0097090)2.57483143
132central nervous system myelination (GO:0022010)2.56157590
133axon ensheathment in central nervous system (GO:0032291)2.56157590
134glycosphingolipid biosynthetic process (GO:0006688)2.55594474
135phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.50452232
136regulation of clathrin-mediated endocytosis (GO:2000369)2.47539390
137positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.45983605
138regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.41446722
139synaptic transmission (GO:0007268)2.41275844
140establishment of protein localization to Golgi (GO:0072600)2.40866287
141regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.40228042
142central nervous system projection neuron axonogenesis (GO:0021952)2.39947673
143potassium ion homeostasis (GO:0055075)2.39402840
144calcium ion-dependent exocytosis (GO:0017156)2.38583034
145vesicle docking involved in exocytosis (GO:0006904)2.36548830
146regulation of exocytosis (GO:0017157)2.34645862

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.66654457
2GBX2_23144817_ChIP-Seq_PC3_Human3.63521766
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.89602145
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.84244609
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75148174
6* REST_21632747_ChIP-Seq_MESCs_Mouse2.67537948
7DROSHA_22980978_ChIP-Seq_HELA_Human2.48869306
8* RARB_27405468_Chip-Seq_BRAIN_Mouse2.47040536
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.46807473
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.46807473
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38371958
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.37262662
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.36986596
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.33325089
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.27415359
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23430208
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.21782073
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.19317728
19REST_18959480_ChIP-ChIP_MESCs_Mouse2.14013581
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.04312413
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.02524538
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.98893395
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.96304693
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.96232484
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94545985
26FLI1_27457419_Chip-Seq_LIVER_Mouse1.94220050
27FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.89934370
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.83652436
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.83222168
30AR_21572438_ChIP-Seq_LNCaP_Human1.81888122
31TAF15_26573619_Chip-Seq_HEK293_Human1.81773416
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.78608116
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.76515227
34* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.73167467
35SMAD4_21799915_ChIP-Seq_A2780_Human1.70071399
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.66943604
37IKZF1_21737484_ChIP-ChIP_HCT116_Human1.66874348
38PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60486836
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.57945882
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.53851902
41MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.51892996
42TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48526059
43NANOG_18555785_Chip-Seq_ESCs_Mouse1.44955833
44NR3C1_23031785_ChIP-Seq_PC12_Mouse1.44174431
45SOX2_21211035_ChIP-Seq_LN229_Gbm1.44062956
46TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39680160
47POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39680160
48SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39324179
49ERG_21242973_ChIP-ChIP_JURKAT_Human1.38488759
50ZFP57_27257070_Chip-Seq_ESCs_Mouse1.38180205
51ZNF274_21170338_ChIP-Seq_K562_Hela1.37435964
52* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37002210
53* P300_19829295_ChIP-Seq_ESCs_Human1.36778951
54STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.35710357
55STAT3_23295773_ChIP-Seq_U87_Human1.33579856
56* SMAD3_21741376_ChIP-Seq_EPCs_Human1.29905240
57* AR_25329375_ChIP-Seq_VCAP_Human1.28575042
58FLI1_21867929_ChIP-Seq_TH2_Mouse1.27528664
59ZNF217_24962896_ChIP-Seq_MCF-7_Human1.27384997
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26984685
61CBP_20019798_ChIP-Seq_JUKART_Human1.26984685
62IGF1R_20145208_ChIP-Seq_DFB_Human1.26873787
63E2F1_18555785_Chip-Seq_ESCs_Mouse1.26823082
64* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26442905
65AR_19668381_ChIP-Seq_PC3_Human1.26287834
66FUS_26573619_Chip-Seq_HEK293_Human1.25920882
67P53_22387025_ChIP-Seq_ESCs_Mouse1.25785303
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.24714339
69* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24207685
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.24071038
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.23190510
72SMAD_19615063_ChIP-ChIP_OVARY_Human1.22042676
73WT1_25993318_ChIP-Seq_PODOCYTE_Human1.21187916
74TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21052546
75PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20596849
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20423542
77CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20020814
78ARNT_22903824_ChIP-Seq_MCF-7_Human1.19278347
79CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19072140
80LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19065803
81RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.18325595
82RING1B_27294783_Chip-Seq_ESCs_Mouse1.17869117
83* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.17531801
84CMYC_18555785_Chip-Seq_ESCs_Mouse1.17238027
85NFE2_27457419_Chip-Seq_LIVER_Mouse1.17113361
86AHR_22903824_ChIP-Seq_MCF-7_Human1.17048630
87VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16778190
88TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.16272421
89VDR_22108803_ChIP-Seq_LS180_Human1.15487195
90CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14974228
91SUZ12_18555785_Chip-Seq_ESCs_Mouse1.14553939
92* TCF4_23295773_ChIP-Seq_U87_Human1.13959956
93P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13203770
94KDM2B_26808549_Chip-Seq_REH_Human1.12573702
95TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11609590
96EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10456466
97PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.10349254
98SALL1_21062744_ChIP-ChIP_HESCs_Human1.10104596
99BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.09084288
100DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08683000
101SMAD3_21741376_ChIP-Seq_HESCs_Human1.08574820
102YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07876813
103TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07529735
104TAL1_26923725_Chip-Seq_HPCs_Mouse1.07119291
105KDM2B_26808549_Chip-Seq_K562_Human1.05520590
106POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05286270
107SMAD4_21741376_ChIP-Seq_EPCs_Human1.05266667
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.05196469
109EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04113726
110SMAD3_21741376_ChIP-Seq_ESCs_Human1.04092759
111TCF4_22108803_ChIP-Seq_LS180_Human1.03609617
112EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.02876115
113BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.02193517
114OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01925141
115TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01276743
116RING1B_27294783_Chip-Seq_NPCs_Mouse1.00810934
117SMAD4_21741376_ChIP-Seq_HESCs_Human0.98820563
118TP53_16413492_ChIP-PET_HCT116_Human0.98267758
119CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.97974010
120CBX2_27304074_Chip-Seq_ESCs_Mouse0.97633242
121GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97181729
122NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97136340
123* RUNX2_22187159_ChIP-Seq_PCA_Human0.97040232
124* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97015202
125* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96877526
126GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95817722
127TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93713455
128* PRDM14_20953172_ChIP-Seq_ESCs_Human0.93684625
129BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93621511
130ZFP281_18757296_ChIP-ChIP_E14_Mouse0.93596236
131UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91821541
132BCAT_22108803_ChIP-Seq_LS180_Human0.91256057
133RXR_22108803_ChIP-Seq_LS180_Human0.90887976
134ER_23166858_ChIP-Seq_MCF-7_Human0.90839331
135PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.90792885
136TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90201989
137RNF2_27304074_Chip-Seq_NSC_Mouse0.89539314
138ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.88141623

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.27836484
2MP0003880_abnormal_central_pattern4.76271669
3MP0003635_abnormal_synaptic_transmissio4.02125186
4MP0004270_analgesia3.82673033
5MP0002063_abnormal_learning/memory/cond3.26350559
6MP0009745_abnormal_behavioral_response3.19101068
7MP0002064_seizures3.08743466
8MP0009046_muscle_twitch3.06986973
9MP0001968_abnormal_touch/_nociception2.87046725
10MP0005423_abnormal_somatic_nervous2.68204589
11MP0002572_abnormal_emotion/affect_behav2.67410494
12MP0002734_abnormal_mechanical_nocicepti2.60204101
13MP0002272_abnormal_nervous_system2.47418874
14MP0001486_abnormal_startle_reflex2.37873571
15MP0002735_abnormal_chemical_nociception2.34266329
16MP0009780_abnormal_chondrocyte_physiolo2.26858200
17MP0000569_abnormal_digit_pigmentation2.22949595
18MP0002822_catalepsy2.20945555
19MP0002736_abnormal_nociception_after2.11483023
20MP0002733_abnormal_thermal_nociception2.07745938
21MP0000778_abnormal_nervous_system2.06573051
22MP0002909_abnormal_adrenal_gland2.04657400
23MP0003329_amyloid_beta_deposits2.04333788
24MP0001501_abnormal_sleep_pattern2.02712941
25MP0001440_abnormal_grooming_behavior2.02634755
26MP0008057_abnormal_DNA_replication1.95985718
27MP0004811_abnormal_neuron_physiology1.95977885
28MP0004858_abnormal_nervous_system1.94119817
29MP0002067_abnormal_sensory_capabilities1.93297134
30MP0001970_abnormal_pain_threshold1.93174240
31MP0006276_abnormal_autonomic_nervous1.92552276
32MP0002184_abnormal_innervation1.89466245
33MP0001984_abnormal_olfaction1.81959103
34MP0001835_abnormal_antigen_presentation1.79197916
35MP0005646_abnormal_pituitary_gland1.79085621
36MP0008877_abnormal_DNA_methylation1.77200144
37MP0008569_lethality_at_weaning1.74123660
38MP0004924_abnormal_behavior1.71136127
39MP0005386_behavior/neurological_phenoty1.71136127
40MP0002557_abnormal_social/conspecific_i1.70920720
41MP0000955_abnormal_spinal_cord1.67321193
42MP0003879_abnormal_hair_cell1.50597995
43MP0002638_abnormal_pupillary_reflex1.50532266
44MP0002882_abnormal_neuron_morphology1.49154241
45MP0005645_abnormal_hypothalamus_physiol1.47640757
46MP0003633_abnormal_nervous_system1.43862271
47MP0003122_maternal_imprinting1.41324087
48MP0002066_abnormal_motor_capabilities/c1.40737469
49MP0003172_abnormal_lysosome_physiology1.30905256
50MP0001502_abnormal_circadian_rhythm1.30329904
51MP0003787_abnormal_imprinting1.26854508
52MP0003631_nervous_system_phenotype1.22633423
53MP0004885_abnormal_endolymph1.19129897
54MP0001529_abnormal_vocalization1.17571310
55MP0010386_abnormal_urinary_bladder1.17307082
56MP0000604_amyloidosis1.16982355
57MP0001986_abnormal_taste_sensitivity1.14926600
58MP0001873_stomach_inflammation1.14597970
59MP0002229_neurodegeneration1.14524353
60MP0005551_abnormal_eye_electrophysiolog1.14295580
61MP0002152_abnormal_brain_morphology1.13623557
62MP0005671_abnormal_response_to1.11072002
63MP0005310_abnormal_salivary_gland1.10150594
64MP0004147_increased_porphyrin_level1.07916987
65MP0004145_abnormal_muscle_electrophysio1.07586104
66MP0004142_abnormal_muscle_tone1.06608586
67MP0003634_abnormal_glial_cell1.05886497
68MP0005174_abnormal_tail_pigmentation1.04703363
69MP0003690_abnormal_glial_cell1.04601361
70MP0001905_abnormal_dopamine_level1.03183977
71MP0000751_myopathy1.01834071
72MP0005499_abnormal_olfactory_system1.00431748
73MP0005394_taste/olfaction_phenotype1.00431748
74MP0002837_dystrophic_cardiac_calcinosis1.00012902
75MP0008961_abnormal_basal_metabolism0.99663652
76MP0000427_abnormal_hair_cycle0.98890480
77MP0000013_abnormal_adipose_tissue0.98851189
78MP0004043_abnormal_pH_regulation0.97461206
79MP0002069_abnormal_eating/drinking_beha0.97343732
80MP0005167_abnormal_blood-brain_barrier0.96618361
81MP0001485_abnormal_pinna_reflex0.95552285
82MP0003045_fibrosis0.94265734
83MP0003121_genomic_imprinting0.94180854
84MP0003632_abnormal_nervous_system0.93450887
85MP0002090_abnormal_vision0.90976886
86MP0003283_abnormal_digestive_organ0.90788434
87MP0003890_abnormal_embryonic-extraembry0.90579137
88MP0004484_altered_response_of0.90277201
89MP0000920_abnormal_myelination0.88641816
90MP0003183_abnormal_peptide_metabolism0.87673545
91MP0005535_abnormal_body_temperature0.86655533
92MP0000015_abnormal_ear_pigmentation0.85376902
93MP0001958_emphysema0.85274701
94MP0005253_abnormal_eye_physiology0.84344581
95MP0004742_abnormal_vestibular_system0.83006008
96MP0008874_decreased_physiological_sensi0.82884908
97MP0004085_abnormal_heartbeat0.81758577
98MP0003195_calcinosis0.81166581
99MP0004233_abnormal_muscle_weight0.80405584
100MP0010307_abnormal_tumor_latency0.80273631
101MP0002752_abnormal_somatic_nervous0.77014542
102MP0004130_abnormal_muscle_cell0.76658374
103MP0001177_atelectasis0.74945713
104MP0004134_abnormal_chest_morphology0.73221783
105MP0002693_abnormal_pancreas_physiology0.72497792
106MP0008872_abnormal_physiological_respon0.70715726
107MP0001963_abnormal_hearing_physiology0.70082352
108MP0004510_myositis0.69561308
109MP0000631_abnormal_neuroendocrine_gland0.68554205
110MP0001299_abnormal_eye_distance/0.66205400
111MP0005187_abnormal_penis_morphology0.64729738
112MP0002102_abnormal_ear_morphology0.64534132
113MP0003075_altered_response_to0.64265021
114MP0002332_abnormal_exercise_endurance0.62123110
115MP0004215_abnormal_myocardial_fiber0.61626226
116MP0003868_abnormal_feces_composition0.59747843
117MP0006072_abnormal_retinal_apoptosis0.58768711
118MP0001188_hyperpigmentation0.58410734
119MP0001943_abnormal_respiration0.57853220
120MP0003861_abnormal_nervous_system0.56905799
121MP0000747_muscle_weakness0.55865854
122MP0001664_abnormal_digestion0.52374443
123MP0010769_abnormal_survival0.51517483
124MP0005409_darkened_coat_color0.51298740
125MP0010770_preweaning_lethality0.50796072
126MP0002082_postnatal_lethality0.50796072
127MP0002876_abnormal_thyroid_physiology0.50465768
128MP0003956_abnormal_body_size0.49933091

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.54822088
2Myokymia (HP:0002411)5.85381134
3Focal seizures (HP:0007359)5.45988624
4Visual hallucinations (HP:0002367)4.99898928
5Epileptic encephalopathy (HP:0200134)4.42739488
6Supranuclear gaze palsy (HP:0000605)4.17914226
7Progressive cerebellar ataxia (HP:0002073)4.12449531
8Atonic seizures (HP:0010819)4.10240706
9Absence seizures (HP:0002121)4.04969776
10Febrile seizures (HP:0002373)3.99231820
11Action tremor (HP:0002345)3.89018616
12Dialeptic seizures (HP:0011146)3.76252390
13Generalized tonic-clonic seizures (HP:0002069)3.70424855
14Ankle clonus (HP:0011448)3.57749748
15Truncal ataxia (HP:0002078)3.38672833
16Impaired vibration sensation in the lower limbs (HP:0002166)3.34384535
17Urinary bladder sphincter dysfunction (HP:0002839)3.28098393
18Depression (HP:0000716)3.17490245
19Mutism (HP:0002300)3.17082099
20Postural instability (HP:0002172)3.13055243
21Drooling (HP:0002307)3.10839376
22Excessive salivation (HP:0003781)3.10839376
23Poor eye contact (HP:0000817)3.10557569
24Hyperventilation (HP:0002883)3.05863475
25Broad-based gait (HP:0002136)3.03296639
26Gaze-evoked nystagmus (HP:0000640)3.03286705
27Dysdiadochokinesis (HP:0002075)2.99664789
28Cerebral inclusion bodies (HP:0100314)2.96123763
29Abnormal social behavior (HP:0012433)2.95969956
30Impaired social interactions (HP:0000735)2.95969956
31Neurofibrillary tangles (HP:0002185)2.94275835
32Abnormal eating behavior (HP:0100738)2.93032351
33Fair hair (HP:0002286)2.92282509
34Dysmetria (HP:0001310)2.87804179
35Urinary urgency (HP:0000012)2.87593003
36Insidious onset (HP:0003587)2.85151402
37Termporal pattern (HP:0011008)2.85151402
38Papilledema (HP:0001085)2.81409209
39Spastic gait (HP:0002064)2.80990016
40Anxiety (HP:0000739)2.76778402
41Amblyopia (HP:0000646)2.74580142
42Epileptiform EEG discharges (HP:0011182)2.73253334
43Abnormality of the lower motor neuron (HP:0002366)2.72261896
44Abnormality of the corticospinal tract (HP:0002492)2.68267628
45Impaired smooth pursuit (HP:0007772)2.65694354
46EEG with generalized epileptiform discharges (HP:0011198)2.65485887
47Papillary thyroid carcinoma (HP:0002895)2.63626966
48Genetic anticipation (HP:0003743)2.62531446
49Pheochromocytoma (HP:0002666)2.59662550
50Polyphagia (HP:0002591)2.57204715
51Generalized hypopigmentation of hair (HP:0011358)2.56907646
52Agitation (HP:0000713)2.53930648
53Hemiparesis (HP:0001269)2.52014242
54Widely spaced teeth (HP:0000687)2.51130904
55Progressive inability to walk (HP:0002505)2.51053328
56Torticollis (HP:0000473)2.49647916
57Hypsarrhythmia (HP:0002521)2.48826140
58Bradykinesia (HP:0002067)2.47169794
59Absent speech (HP:0001344)2.43263404
60Scanning speech (HP:0002168)2.42285772
61Lower limb muscle weakness (HP:0007340)2.41873501
62Abnormality of ocular smooth pursuit (HP:0000617)2.38926137
63Intention tremor (HP:0002080)2.29133465
64Dysmetric saccades (HP:0000641)2.29105487
65Impaired vibratory sensation (HP:0002495)2.28961265
66Amyotrophic lateral sclerosis (HP:0007354)2.28386358
67Diplopia (HP:0000651)2.26931816
68Abnormality of binocular vision (HP:0011514)2.26931816
69Focal dystonia (HP:0004373)2.25949024
70Abnormal hair whorl (HP:0010721)2.23152420
71Hemiplegia (HP:0002301)2.21469123
72Neuronal loss in central nervous system (HP:0002529)2.21379095
73Neuroendocrine neoplasm (HP:0100634)2.17710803
74Blue irides (HP:0000635)2.15864358
75Stereotypic behavior (HP:0000733)2.15817305
76Limb dystonia (HP:0002451)2.15452228
77Morphological abnormality of the pyramidal tract (HP:0002062)2.14913983
78Status epilepticus (HP:0002133)2.13363239
79Failure to thrive in infancy (HP:0001531)2.13117473
80Inappropriate behavior (HP:0000719)2.11945225
81T lymphocytopenia (HP:0005403)2.10021673
82Inability to walk (HP:0002540)2.09760154
83Generalized myoclonic seizures (HP:0002123)2.09407708
84Clonus (HP:0002169)2.02727331
85Craniofacial dystonia (HP:0012179)2.01564070
86Megalencephaly (HP:0001355)2.01544813
87Abnormality of salivation (HP:0100755)2.01437740
88Prolonged QT interval (HP:0001657)2.01151604
89Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.99487548
90Bundle branch block (HP:0011710)1.96513279
91Increased circulating renin level (HP:0000848)1.95769465
92Gait ataxia (HP:0002066)1.95262191
93Degeneration of the lateral corticospinal tracts (HP:0002314)1.93316021
94Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.93316021
95Insomnia (HP:0100785)1.92112979
96Exotropia (HP:0000577)1.91641535
97Specific learning disability (HP:0001328)1.91616865
98Stomatitis (HP:0010280)1.88947812
99Ventricular fibrillation (HP:0001663)1.88782575
100Abnormality of saccadic eye movements (HP:0000570)1.88446370
101Rapidly progressive (HP:0003678)1.87465638
102Truncal obesity (HP:0001956)1.86114836
103Rigidity (HP:0002063)1.85592045
104Apathy (HP:0000741)1.83533380
105Psychosis (HP:0000709)1.83202324
106Central scotoma (HP:0000603)1.82957417
107Protruding tongue (HP:0010808)1.82414952
108Aplasia/Hypoplasia of the brainstem (HP:0007362)1.81307337
109Hypoplasia of the brainstem (HP:0002365)1.81307337
110Akinesia (HP:0002304)1.81019017
111Thyroid carcinoma (HP:0002890)1.80607539
112Frequent falls (HP:0002359)1.78379576
113Abnormality of T cell number (HP:0011839)1.77931450
114Lower limb amyotrophy (HP:0007210)1.77066325
115Clumsiness (HP:0002312)1.76969142
116Incomplete penetrance (HP:0003829)1.76887667
117Paraplegia (HP:0010550)1.75133282
118Menstrual irregularities (HP:0000858)1.72141580
119Renal cortical cysts (HP:0000803)1.70827659
120Spastic paraplegia (HP:0001258)1.67578243
121Limb ataxia (HP:0002070)1.66711885
122Abnormality of the renal cortex (HP:0011035)1.65507156
123Short chin (HP:0000331)1.64655547
124Abnormality of the periventricular white matter (HP:0002518)1.64429561
125Syncope (HP:0001279)1.63464528
126Chronic hepatic failure (HP:0100626)1.62316577
127Gait imbalance (HP:0002141)1.62128076
128Abnormal EKG (HP:0003115)1.61811485
129Hypothermia (HP:0002045)1.60623178

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.26869279
2MAP3K93.99924851
3EPHA43.66110564
4FRK3.63922430
5MARK13.33073975
6MAP3K43.22442770
7MINK12.80127521
8DAPK22.40541085
9MAP2K72.34105085
10PAK62.33555357
11NTRK22.06922875
12MAP2K42.04537604
13NTRK12.00861139
14KSR21.97554494
15RIPK41.97390964
16PRKD31.86299644
17MAP4K21.81452044
18CAMKK11.78408840
19AKT31.74360667
20TXK1.67118953
21MAP3K121.67114400
22KSR11.61378948
23CDK51.57178692
24ACVR1B1.45554510
25CASK1.44896599
26PLK21.40297794
27DAPK11.37690061
28PNCK1.33437034
29MAP3K21.32198800
30MAP3K131.30725504
31UHMK11.25062078
32SIK21.24317966
33GRK51.21652008
34STK381.19610592
35FES1.18613365
36MAPK131.18008454
37WNK31.17629009
38PHKG11.17286431
39PHKG21.17286431
40ARAF1.15872752
41PRKCG1.14924276
42CAMK1D1.14302032
43SGK4941.12131837
44SGK2231.12131837
45CAMKK21.11636666
46TYRO31.09665991
47CDK191.05732548
48RET1.03702615
49ICK1.01482526
50SGK20.97722508
51CAMK1G0.94219781
52ERBB30.94048460
53TNIK0.93587062
54PRKCH0.92970597
55SGK30.92364607
56CAMK2A0.89852744
57OBSCN0.88688588
58PAK30.86498175
59LATS20.85799877
60PRPF4B0.85735599
61BMPR20.83300404
62LMTK20.82494178
63SCYL20.81347917
64CDK140.80974233
65BMPR1B0.80878369
66CDK180.80432432
67JAK10.79466468
68STK110.79044495
69CSNK1G20.78624757
70SGK10.77672539
71CDK150.77360231
72PTK2B0.77285833
73TAOK30.74908958
74NEK60.74461463
75PINK10.73843215
76CAMK10.73748376
77NLK0.70605506
78CAMK2B0.69620796
79WNK10.68558447
80CDK30.68249061
81PIK3CG0.68241259
82BRD40.67937475
83MARK20.66436691
84PDK10.64816357
85RAF10.63548785
86TRIM280.63499042
87BLK0.63482641
88CDK11A0.63084645
89FER0.62791820
90PDPK10.62616733
91TEC0.60895831
92TAOK10.59890314
93OXSR10.58802121
94MAP3K10.58711581
95PRKG10.58494854
96SYK0.58018844
97PRKCZ0.57814226
98JAK20.55570577
99FGFR20.55234852
100DYRK1A0.54968802
101RPS6KA30.53736686
102MAPK100.52310226
103STK390.51609947
104FYN0.51278455
105ALK0.50882037
106MAP2K60.50722654
107CSNK1G10.50563511
108MAPK120.50358071
109PRKCE0.50262844
110INSRR0.49518260
111FGFR30.47082578
112BCR0.46751887
113MAP3K70.46202122
114MAP2K10.45586926
115RPS6KA20.45516759
116TRPM70.44517450
117CSNK1D0.44489117
118CDC42BPA0.42734423
119FGR0.42727528
120CAMK2D0.41609297
121IRAK20.39467111
122CSNK1A1L0.38944725
123MAP3K60.38481141
124EIF2AK30.37874628
125ITK0.37662229
126DMPK0.37623337
127PKN10.37432914
128PRKAA10.36865410
129CAMK40.36749036
130TNK20.36426532
131NEK10.35649159
132PRKCB0.34773470
133CAMK2G0.34641889
134ROCK20.33187537

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.32353793
2Synaptic vesicle cycle_Homo sapiens_hsa047213.28160694
3GABAergic synapse_Homo sapiens_hsa047272.51703922
4Circadian entrainment_Homo sapiens_hsa047132.48993138
5Olfactory transduction_Homo sapiens_hsa047402.46765768
6Long-term potentiation_Homo sapiens_hsa047202.46713877
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.44333670
8Glutamatergic synapse_Homo sapiens_hsa047242.35387649
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.27793547
10Morphine addiction_Homo sapiens_hsa050322.26602849
11Amphetamine addiction_Homo sapiens_hsa050312.22595964
12Insulin secretion_Homo sapiens_hsa049112.13009093
13Dopaminergic synapse_Homo sapiens_hsa047282.06622269
14Salivary secretion_Homo sapiens_hsa049702.03828687
15Cholinergic synapse_Homo sapiens_hsa047251.83529534
16Gastric acid secretion_Homo sapiens_hsa049711.75481045
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.73870402
18Renin secretion_Homo sapiens_hsa049241.69368268
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.62485970
20Taste transduction_Homo sapiens_hsa047421.62226909
21Oxytocin signaling pathway_Homo sapiens_hsa049211.54565832
22Cocaine addiction_Homo sapiens_hsa050301.54007480
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.53593945
24Regulation of autophagy_Homo sapiens_hsa041401.53384708
25Collecting duct acid secretion_Homo sapiens_hsa049661.53367140
26Type II diabetes mellitus_Homo sapiens_hsa049301.49690196
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.48889583
28Long-term depression_Homo sapiens_hsa047301.48625199
29Serotonergic synapse_Homo sapiens_hsa047261.48218142
30Calcium signaling pathway_Homo sapiens_hsa040201.43201022
31GnRH signaling pathway_Homo sapiens_hsa049121.40209020
32Gap junction_Homo sapiens_hsa045401.34874933
33Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26479090
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.23850469
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.19806945
36Nitrogen metabolism_Homo sapiens_hsa009101.19001193
37cAMP signaling pathway_Homo sapiens_hsa040241.15842474
38Glioma_Homo sapiens_hsa052141.15640571
39Estrogen signaling pathway_Homo sapiens_hsa049151.15453173
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14424098
41Axon guidance_Homo sapiens_hsa043601.13798504
42Dorso-ventral axis formation_Homo sapiens_hsa043201.12346443
43Vibrio cholerae infection_Homo sapiens_hsa051101.03415171
44ErbB signaling pathway_Homo sapiens_hsa040121.03168791
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.02521373
46T cell receptor signaling pathway_Homo sapiens_hsa046600.99133718
47Phototransduction_Homo sapiens_hsa047440.95444842
48Melanogenesis_Homo sapiens_hsa049160.90233495
49Vascular smooth muscle contraction_Homo sapiens_hsa042700.87178029
50Phospholipase D signaling pathway_Homo sapiens_hsa040720.86298084
51Carbohydrate digestion and absorption_Homo sapiens_hsa049730.85833337
52Pancreatic secretion_Homo sapiens_hsa049720.85160817
53Rheumatoid arthritis_Homo sapiens_hsa053230.83326030
54Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.83291703
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.80180978
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79209926
57Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79121932
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.78825344
59Thyroid hormone synthesis_Homo sapiens_hsa049180.77573489
60Oocyte meiosis_Homo sapiens_hsa041140.75883695
61African trypanosomiasis_Homo sapiens_hsa051430.75746416
62Butanoate metabolism_Homo sapiens_hsa006500.75720614
63Choline metabolism in cancer_Homo sapiens_hsa052310.75379977
64Neurotrophin signaling pathway_Homo sapiens_hsa047220.74555489
65Cardiac muscle contraction_Homo sapiens_hsa042600.74470223
66Dilated cardiomyopathy_Homo sapiens_hsa054140.71080007
67mTOR signaling pathway_Homo sapiens_hsa041500.70881326
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69367729
69Glucagon signaling pathway_Homo sapiens_hsa049220.68879676
70MAPK signaling pathway_Homo sapiens_hsa040100.67575069
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65941072
72VEGF signaling pathway_Homo sapiens_hsa043700.63892210
73Platelet activation_Homo sapiens_hsa046110.63431497
74Bile secretion_Homo sapiens_hsa049760.63335579
75ABC transporters_Homo sapiens_hsa020100.62447963
76Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62088969
77Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61453934
78Inositol phosphate metabolism_Homo sapiens_hsa005620.61403444
79Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60043078
80Fatty acid biosynthesis_Homo sapiens_hsa000610.58306724
81Endometrial cancer_Homo sapiens_hsa052130.57940566
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.57268655
83Allograft rejection_Homo sapiens_hsa053300.56695799
84Insulin signaling pathway_Homo sapiens_hsa049100.56639806
85Endocytosis_Homo sapiens_hsa041440.56499788
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.56462823
87Ras signaling pathway_Homo sapiens_hsa040140.52638606
88Prion diseases_Homo sapiens_hsa050200.50636362
89Renal cell carcinoma_Homo sapiens_hsa052110.49938422
90Graft-versus-host disease_Homo sapiens_hsa053320.49492410
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49485343
92Alcoholism_Homo sapiens_hsa050340.49181704
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48718066
94Ether lipid metabolism_Homo sapiens_hsa005650.48372774
95Non-small cell lung cancer_Homo sapiens_hsa052230.48287585
96Rap1 signaling pathway_Homo sapiens_hsa040150.48210221
97Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48039912
98Osteoclast differentiation_Homo sapiens_hsa043800.47093767
99FoxO signaling pathway_Homo sapiens_hsa040680.45143017
100Tuberculosis_Homo sapiens_hsa051520.44627358
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41296288
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41172378
103Circadian rhythm_Homo sapiens_hsa047100.39913202
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38377072
105Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38322524
106Type I diabetes mellitus_Homo sapiens_hsa049400.37613373
107Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37426726
108Primary bile acid biosynthesis_Homo sapiens_hsa001200.36686358
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.36559754
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.35393480
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34919328
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34701195
113Amoebiasis_Homo sapiens_hsa051460.34310720
114beta-Alanine metabolism_Homo sapiens_hsa004100.33688970
115Chemokine signaling pathway_Homo sapiens_hsa040620.33100360
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.32708534
117Wnt signaling pathway_Homo sapiens_hsa043100.32118367
118Ovarian steroidogenesis_Homo sapiens_hsa049130.30997313
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30974558
120Prolactin signaling pathway_Homo sapiens_hsa049170.30426809
121Colorectal cancer_Homo sapiens_hsa052100.29634973
122AMPK signaling pathway_Homo sapiens_hsa041520.28687102
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.28323871

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