WDR70

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)4.57330356
2telomere maintenance via semi-conservative replication (GO:0032201)4.49638565
3replication fork processing (GO:0031297)4.39464785
4DNA strand elongation involved in DNA replication (GO:0006271)4.35930847
5nuclear pore complex assembly (GO:0051292)4.35643932
6CENP-A containing nucleosome assembly (GO:0034080)4.33128562
7maturation of SSU-rRNA (GO:0030490)4.26280839
8DNA strand elongation (GO:0022616)4.20776031
9telomere maintenance via recombination (GO:0000722)4.13058632
10nuclear pore organization (GO:0006999)4.12391927
11chromatin remodeling at centromere (GO:0031055)4.08434599
12ribosomal small subunit biogenesis (GO:0042274)4.06224422
13DNA replication initiation (GO:0006270)4.03691924
14DNA deamination (GO:0045006)3.98356001
15DNA replication checkpoint (GO:0000076)3.92161517
16pore complex assembly (GO:0046931)3.82218140
17kinetochore assembly (GO:0051382)3.78437833
18mitotic recombination (GO:0006312)3.78172835
19kinetochore organization (GO:0051383)3.70237496
20telomere maintenance via telomere lengthening (GO:0010833)3.64068071
21lactate metabolic process (GO:0006089)3.57847349
22establishment of protein localization to mitochondrial membrane (GO:0090151)3.57218135
23DNA replication-independent nucleosome organization (GO:0034724)3.55971261
24DNA replication-independent nucleosome assembly (GO:0006336)3.55971261
25adaptation of signaling pathway (GO:0023058)3.54873532
26viral transcription (GO:0019083)3.52487069
27translational termination (GO:0006415)3.43560392
28ribosome assembly (GO:0042255)3.43131726
29nucleotide-excision repair, DNA gap filling (GO:0006297)3.42736344
30ribosomal large subunit biogenesis (GO:0042273)3.40173014
31ribonucleoprotein complex biogenesis (GO:0022613)3.38838440
32histone exchange (GO:0043486)3.34991672
33termination of RNA polymerase III transcription (GO:0006386)3.31857957
34transcription elongation from RNA polymerase III promoter (GO:0006385)3.31857957
35mitotic metaphase plate congression (GO:0007080)3.29659871
36exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.29099700
37rRNA modification (GO:0000154)3.28282132
38spliceosomal snRNP assembly (GO:0000387)3.26441374
39mitotic nuclear envelope disassembly (GO:0007077)3.25868465
40pseudouridine synthesis (GO:0001522)3.25836749
41transcription-coupled nucleotide-excision repair (GO:0006283)3.24101633
42nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.23878993
43rRNA processing (GO:0006364)3.23047799
44SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.22057005
45DNA replication-dependent nucleosome organization (GO:0034723)3.21194735
46DNA replication-dependent nucleosome assembly (GO:0006335)3.21194735
47cotranslational protein targeting to membrane (GO:0006613)3.20762798
487-methylguanosine mRNA capping (GO:0006370)3.19644190
49RNA capping (GO:0036260)3.19411991
507-methylguanosine RNA capping (GO:0009452)3.19411991
51somatic diversification of immune receptors via somatic mutation (GO:0002566)3.15099259
52somatic hypermutation of immunoglobulin genes (GO:0016446)3.15099259
53proteasome assembly (GO:0043248)3.15090471
54protein targeting to ER (GO:0045047)3.14748977
55mitotic sister chromatid segregation (GO:0000070)3.13479854
56rRNA metabolic process (GO:0016072)3.13118922
57establishment of integrated proviral latency (GO:0075713)3.13001322
58ribosome biogenesis (GO:0042254)3.12566475
59DNA catabolic process, exonucleolytic (GO:0000738)3.11501452
60negative regulation of chromosome segregation (GO:0051985)3.08843776
61negative regulation of mitotic sister chromatid separation (GO:2000816)3.07698697
62negative regulation of sister chromatid segregation (GO:0033046)3.07698697
63negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.07698697
64negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.07698697
65negative regulation of mitotic sister chromatid segregation (GO:0033048)3.07698697
66regulation of mitochondrial translation (GO:0070129)3.07122407
67spindle checkpoint (GO:0031577)3.04726941
68negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.04053317
69regulation of centriole replication (GO:0046599)3.02290789
70RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.01789000
71regulation of mitotic sister chromatid separation (GO:0010965)3.00927183
72regulation of mitotic sister chromatid segregation (GO:0033047)3.00927183
73regulation of sister chromatid segregation (GO:0033045)3.00927183
74mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.00769291
75translational initiation (GO:0006413)3.00521631
76sister chromatid segregation (GO:0000819)3.00506046
77regulation of translational elongation (GO:0006448)2.99959515
78chaperone-mediated protein transport (GO:0072321)2.99775957
79formation of translation preinitiation complex (GO:0001731)2.99517507
80mitotic spindle checkpoint (GO:0071174)2.98318596
81double-strand break repair via nonhomologous end joining (GO:0006303)2.97859068
82non-recombinational repair (GO:0000726)2.97859068
83regulation of mitotic metaphase/anaphase transition (GO:0030071)2.97299503
84regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.97299503
85deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.96187935
86protein localization to endoplasmic reticulum (GO:0070972)2.95927599
87establishment of protein localization to endoplasmic reticulum (GO:0072599)2.95683494
88regulation of nuclear cell cycle DNA replication (GO:0033262)2.95540884
89resolution of meiotic recombination intermediates (GO:0000712)2.94231171
90DNA double-strand break processing (GO:0000729)2.94027691
91mitotic spindle assembly checkpoint (GO:0007094)2.93043223
92metaphase plate congression (GO:0051310)2.92365328
93spindle assembly checkpoint (GO:0071173)2.91083697
94translational elongation (GO:0006414)2.90949283
95purine nucleobase biosynthetic process (GO:0009113)2.90622259
96nuclear envelope disassembly (GO:0051081)2.90023530
97membrane disassembly (GO:0030397)2.90023530
98regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.89366529
99regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.88503319
100synapsis (GO:0007129)2.87404196
101termination of RNA polymerase II transcription (GO:0006369)2.86880504
102rRNA methylation (GO:0031167)2.86760344
103amino acid activation (GO:0043038)2.85830842
104tRNA aminoacylation (GO:0043039)2.85830842
105regulation of chromosome segregation (GO:0051983)2.85496531
106transcription elongation from RNA polymerase I promoter (GO:0006362)2.84421246
107anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.82904724
108respiratory chain complex IV assembly (GO:0008535)2.82813328
109nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.81753111
110negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.81721274
111negative regulation of ligase activity (GO:0051352)2.81721274
112tRNA aminoacylation for protein translation (GO:0006418)2.80931093
113positive regulation of mitotic sister chromatid separation (GO:1901970)2.80453510
114positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.80453510
115positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.80453510
116positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.80349535
117histone mRNA metabolic process (GO:0008334)2.80035069
118regulation of double-strand break repair via homologous recombination (GO:0010569)2.77996081
119protein localization to chromosome, centromeric region (GO:0071459)2.77711932
120nucleobase biosynthetic process (GO:0046112)2.77505405
121translation (GO:0006412)2.77117032
122viral mRNA export from host cell nucleus (GO:0046784)2.75868920
123negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.75787610
124centriole replication (GO:0007099)2.75470730
125DNA ligation (GO:0006266)2.74395301
126negative regulation of DNA-dependent DNA replication (GO:2000104)2.74361745
127tRNA methylation (GO:0030488)2.74240516
128mismatch repair (GO:0006298)2.73952635
129protein complex biogenesis (GO:0070271)2.73215662
130nucleotide-excision repair (GO:0006289)2.73139763
131mitochondrial respiratory chain complex assembly (GO:0033108)2.72678858
132attachment of spindle microtubules to kinetochore (GO:0008608)2.71824603
133cellular component biogenesis (GO:0044085)2.71646796
134establishment of viral latency (GO:0019043)2.71445533
135cellular protein complex disassembly (GO:0043624)2.70461937
136telomere maintenance (GO:0000723)2.69246166
137DNA damage response, detection of DNA damage (GO:0042769)2.69113496
138transcription from RNA polymerase I promoter (GO:0006360)2.68563808
139termination of RNA polymerase I transcription (GO:0006363)2.68474049
140meiotic chromosome segregation (GO:0045132)2.68461751
141microtubule depolymerization (GO:0007019)2.68453801
142cell cycle G1/S phase transition (GO:0044843)2.68267707
143G1/S transition of mitotic cell cycle (GO:0000082)2.68267707
144telomere organization (GO:0032200)2.67904982
145viral life cycle (GO:0019058)2.67065943
146maturation of 5.8S rRNA (GO:0000460)2.66107983
147maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.65997014
148GTP biosynthetic process (GO:0006183)2.65708723
149DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.64779880
150RNA-dependent DNA replication (GO:0006278)2.63982914
151spliceosomal complex assembly (GO:0000245)2.62818469
152protein localization to kinetochore (GO:0034501)2.62221146
153signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.60544954
154signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.60544954
155signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.60544954
156intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.59132209
157signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.59132209
158DNA unwinding involved in DNA replication (GO:0006268)2.58393659
159ncRNA processing (GO:0034470)2.58160830
160IMP biosynthetic process (GO:0006188)2.56883726

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.63329960
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.14477772
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.84221712
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.82070816
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.59702906
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.50542982
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.36533600
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.23181473
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.18614728
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.03795528
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.98120294
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.87168777
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.83682317
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.82203107
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.81773086
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.81292539
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78860650
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.78675646
19MYC_19079543_ChIP-ChIP_MESCs_Mouse2.76233076
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.56775263
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.52809636
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.52417523
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.46861924
24VDR_23849224_ChIP-Seq_CD4+_Human2.41580093
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.31429296
26* ELK1_19687146_ChIP-ChIP_HELA_Human2.22902484
27FOXP3_21729870_ChIP-Seq_TREG_Human2.21314699
28* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.14358509
29NELFA_20434984_ChIP-Seq_ESCs_Mouse2.11197657
30IGF1R_20145208_ChIP-Seq_DFB_Human2.09252500
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.09179730
32XRN2_22483619_ChIP-Seq_HELA_Human2.07006913
33YY1_21170310_ChIP-Seq_MESCs_Mouse2.05031642
34SRF_21415370_ChIP-Seq_HL-1_Mouse2.03163642
35* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.98845192
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.97303068
37SALL1_21062744_ChIP-ChIP_HESCs_Human1.95072111
38TTF2_22483619_ChIP-Seq_HELA_Human1.94660636
39DCP1A_22483619_ChIP-Seq_HELA_Human1.94248820
40E2F1_18555785_ChIP-Seq_MESCs_Mouse1.90152529
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.88335028
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.88184247
43FUS_26573619_Chip-Seq_HEK293_Human1.88172233
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.83245130
45* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.80444209
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.75744918
47GABP_19822575_ChIP-Seq_HepG2_Human1.70183088
48SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.68644756
49FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.64917395
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63043724
51* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62950251
52E2F1_21310950_ChIP-Seq_MCF-7_Human1.62582180
53BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.61365976
54* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61001801
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.60128931
56ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.55414159
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.52567677
58HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.49566345
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.48688124
60GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45568571
61GBX2_23144817_ChIP-Seq_PC3_Human1.41892804
62SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39606260
63IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.39293581
64ZNF274_21170338_ChIP-Seq_K562_Hela1.35683230
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.30924433
66MYC_18940864_ChIP-ChIP_HL60_Human1.30094387
67NANOG_18555785_ChIP-Seq_MESCs_Mouse1.28075334
68ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.27166127
69* SPI1_23547873_ChIP-Seq_NB4_Human1.25208305
70KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.24483071
71IRF8_21731497_ChIP-ChIP_J774_Mouse1.16769116
72POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16598646
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.15357375
74VDR_22108803_ChIP-Seq_LS180_Human1.15286868
75PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13865571
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.12405751
77AR_21909140_ChIP-Seq_LNCAP_Human1.11648960
78CIITA_25753668_ChIP-Seq_RAJI_Human1.11294480
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11009189
80PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10200155
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06963318
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06583712
83CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.04376025
84E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01800535
85HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.99135149
86CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.98767269
87KDM5A_27292631_Chip-Seq_BREAST_Human0.98586366
88TAF15_26573619_Chip-Seq_HEK293_Human0.98186950
89GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97905132
90SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97286957
91PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.96847211
92MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.96159945
93RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94241819
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.93060731
95* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92415001
96TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90285883
97TFEB_21752829_ChIP-Seq_HELA_Human0.90257185
98POU5F1_16153702_ChIP-ChIP_HESCs_Human0.90188443
99IRF1_19129219_ChIP-ChIP_H3396_Human0.89164853
100SOX2_16153702_ChIP-ChIP_HESCs_Human0.87135193
101P300_19829295_ChIP-Seq_ESCs_Human0.85227607
102CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.84944831
103ZFP57_27257070_Chip-Seq_ESCs_Mouse0.83735160
104BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.83691252
105EWS_26573619_Chip-Seq_HEK293_Human0.83612854
106CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.83607073
107RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.83564873
108TP53_22573176_ChIP-Seq_HFKS_Human0.83470760
109SCL_19346495_ChIP-Seq_HPC-7_Human0.83253357
110CTBP2_25329375_ChIP-Seq_LNCAP_Human0.80237749
111DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.78566033
112NANOG_16153702_ChIP-ChIP_HESCs_Human0.78528366
113FLI1_27457419_Chip-Seq_LIVER_Mouse0.78364638
114CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.78198026
115EGR1_19374776_ChIP-ChIP_THP-1_Human0.77759440
116BP1_19119308_ChIP-ChIP_Hs578T_Human0.77228333
117* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77203909
118* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.75538821
119* CBP_20019798_ChIP-Seq_JUKART_Human0.75538821
120KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.74520504
121KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.74520504
122KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.74520504
123RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.74503559
124SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.74125036
125STAT4_19710469_ChIP-ChIP_TH1__Mouse0.73491234
126CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73147840
127NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.72689866
128HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.70173359

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.15644835
2MP0008058_abnormal_DNA_repair3.83349984
3MP0010094_abnormal_chromosome_stability3.81613733
4MP0003693_abnormal_embryo_hatching3.67364220
5MP0003111_abnormal_nucleus_morphology3.20527305
6MP0003077_abnormal_cell_cycle3.16134646
7MP0004957_abnormal_blastocyst_morpholog2.98792655
8MP0002396_abnormal_hematopoietic_system2.70624407
9MP0008007_abnormal_cellular_replicative2.64105019
10MP0008932_abnormal_embryonic_tissue2.51857844
11MP0000569_abnormal_digit_pigmentation2.40883640
12MP0009697_abnormal_copulation2.40090409
13MP0006292_abnormal_olfactory_placode2.29525380
14MP0008877_abnormal_DNA_methylation2.24342569
15MP0003786_premature_aging2.12645850
16MP0000490_abnormal_crypts_of2.07182294
17MP0003806_abnormal_nucleotide_metabolis1.93685708
18MP0001188_hyperpigmentation1.91335359
19MP0003718_maternal_effect1.83597977
20MP0006072_abnormal_retinal_apoptosis1.83371917
21MP0005174_abnormal_tail_pigmentation1.80634417
22MP0003787_abnormal_imprinting1.78744968
23MP0009333_abnormal_splenocyte_physiolog1.73262945
24MP0000015_abnormal_ear_pigmentation1.71952522
25MP0008789_abnormal_olfactory_epithelium1.69312112
26MP0003136_yellow_coat_color1.68045753
27MP0005499_abnormal_olfactory_system1.61214970
28MP0005394_taste/olfaction_phenotype1.61214970
29MP0009785_altered_susceptibility_to1.60184798
30MP0005671_abnormal_response_to1.59878108
31MP0005075_abnormal_melanosome_morpholog1.50047070
32MP0001835_abnormal_antigen_presentation1.49425627
33MP0002095_abnormal_skin_pigmentation1.48874948
34MP0000372_irregular_coat_pigmentation1.46916254
35MP0002102_abnormal_ear_morphology1.44181914
36MP0003724_increased_susceptibility_to1.43036722
37MP0004808_abnormal_hematopoietic_stem1.41618224
38MP0009379_abnormal_foot_pigmentation1.39101509
39MP0003763_abnormal_thymus_physiology1.38990895
40MP0002398_abnormal_bone_marrow1.37740979
41MP0002148_abnormal_hypersensitivity_rea1.36311981
42MP0005410_abnormal_fertilization1.32738835
43MP0006035_abnormal_mitochondrial_morpho1.32088351
44MP0000350_abnormal_cell_proliferation1.26527178
45MP0004133_heterotaxia1.23189041
46MP0002938_white_spotting1.21414899
47MP0000049_abnormal_middle_ear1.21094547
48MP0000689_abnormal_spleen_morphology1.20701358
49MP0005187_abnormal_penis_morphology1.20365526
50MP0002019_abnormal_tumor_incidence1.19068589
51MP0006036_abnormal_mitochondrial_physio1.19058689
52MP0002722_abnormal_immune_system1.18462068
53MP0000313_abnormal_cell_death1.18177815
54MP0000358_abnormal_cell_content/1.15416357
55MP0005000_abnormal_immune_tolerance1.13446233
56MP0003123_paternal_imprinting1.13171965
57MP0002420_abnormal_adaptive_immunity1.12130511
58MP0001545_abnormal_hematopoietic_system1.11972277
59MP0005397_hematopoietic_system_phenotyp1.11972277
60MP0005389_reproductive_system_phenotype1.11576727
61MP0001819_abnormal_immune_cell1.10819946
62MP0002452_abnormal_antigen_presenting1.10378236
63MP0002723_abnormal_immune_serum1.10265432
64MP0002210_abnormal_sex_determination1.10098614
65MP0000703_abnormal_thymus_morphology1.09780369
66MP0005409_darkened_coat_color1.09622008
67MP0001800_abnormal_humoral_immune1.08463526
68MP0000716_abnormal_immune_system1.07752882
69MP0005253_abnormal_eye_physiology1.05806380
70MP0005025_abnormal_response_to1.05633104
71MP0001730_embryonic_growth_arrest1.05388566
72MP0002429_abnormal_blood_cell1.05267861
73MP0003698_abnormal_male_reproductive1.02483566
74MP0003567_abnormal_fetal_cardiomyocyte1.01789664
75MP0002751_abnormal_autonomic_nervous1.00571253
76MP0001905_abnormal_dopamine_level0.99479415
77MP0002638_abnormal_pupillary_reflex0.98265427
78MP0010307_abnormal_tumor_latency0.98254364
79MP0004134_abnormal_chest_morphology0.96983407
80MP0002837_dystrophic_cardiac_calcinosis0.96034471
81MP0005391_vision/eye_phenotype0.95929472
82MP0001929_abnormal_gametogenesis0.95517272
83MP0003315_abnormal_perineum_morphology0.94920718
84MP0004145_abnormal_muscle_electrophysio0.94444856
85MP0002088_abnormal_embryonic_growth/wei0.93164186
86MP0000566_synostosis0.92474221
87MP0001145_abnormal_male_reproductive0.92220024
88MP0002234_abnormal_pharynx_morphology0.91696568
89MP0001764_abnormal_homeostasis0.91383159
90MP0002405_respiratory_system_inflammati0.90968196
91MP0001529_abnormal_vocalization0.90841867
92MP0003121_genomic_imprinting0.90627441
93MP0002132_abnormal_respiratory_system0.90567001
94MP0003984_embryonic_growth_retardation0.90139456
95MP0003186_abnormal_redox_activity0.89684545
96MP0002163_abnormal_gland_morphology0.87797275
97MP0003937_abnormal_limbs/digits/tail_de0.87241524
98MP0002160_abnormal_reproductive_system0.86708170
99MP0001697_abnormal_embryo_size0.86306966
100MP0001186_pigmentation_phenotype0.84303600
101MP0008260_abnormal_autophagy0.84122164
102MP0008995_early_reproductive_senescence0.83638576
103MP0001286_abnormal_eye_development0.82681246
104MP0000647_abnormal_sebaceous_gland0.81893003
105MP0002933_joint_inflammation0.81481328
106MP0000858_altered_metastatic_potential0.81095120
107MP0002092_abnormal_eye_morphology0.80787937
108MP0005395_other_phenotype0.80475680
109MP0002419_abnormal_innate_immunity0.80289219
110MP0001853_heart_inflammation0.80094028
111MP0003890_abnormal_embryonic-extraembry0.80053468
112MP0001661_extended_life_span0.79425093
113MP0001672_abnormal_embryogenesis/_devel0.79195682
114MP0005380_embryogenesis_phenotype0.79195682
115MP0000653_abnormal_sex_gland0.78823227
116MP0000428_abnormal_craniofacial_morphol0.78706636
117MP0003943_abnormal_hepatobiliary_system0.78699819
118MP0002085_abnormal_embryonic_tissue0.78533472
119MP0003385_abnormal_body_wall0.78117574
120MP0003941_abnormal_skin_development0.77336506
121MP0001119_abnormal_female_reproductive0.77125124
122MP0002177_abnormal_outer_ear0.76912050
123MP0002269_muscular_atrophy0.76875745
124MP0003938_abnormal_ear_development0.76431617
125MP0002697_abnormal_eye_size0.76117443
126MP0003699_abnormal_female_reproductive0.75907916
127MP0010030_abnormal_orbit_morphology0.75642906
128MP0002111_abnormal_tail_morphology0.75640155
129MP0002233_abnormal_nose_morphology0.75339884
130MP0000631_abnormal_neuroendocrine_gland0.75338233
131MP0002080_prenatal_lethality0.75115417
132MP0003646_muscle_fatigue0.74982106
133MP0000383_abnormal_hair_follicle0.74763922
134MP0000685_abnormal_immune_system0.74188773
135MP0005171_absent_coat_pigmentation0.72247038
136MP0004197_abnormal_fetal_growth/weight/0.71886709
137MP0002161_abnormal_fertility/fecundity0.71543810
138MP0002075_abnormal_coat/hair_pigmentati0.70987471
139MP0005647_abnormal_sex_gland0.70584203
140MP0003436_decreased_susceptibility_to0.68940900
141MP0004142_abnormal_muscle_tone0.68039392
142MP0001324_abnormal_eye_pigmentation0.67536578
143MP0009250_abnormal_appendicular_skeleto0.67395532
144MP0002084_abnormal_developmental_patter0.64844642
145MP0001727_abnormal_embryo_implantation0.64718151
146MP0001293_anophthalmia0.64249525
147MP0002249_abnormal_larynx_morphology0.62522150
148MP0009703_decreased_birth_body0.62152141
149MP0005257_abnormal_intraocular_pressure0.61504424
150MP0000750_abnormal_muscle_regeneration0.61083021

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.58486546
2Chromsome breakage (HP:0040012)4.53230178
3Reticulocytopenia (HP:0001896)3.90825774
4Birth length less than 3rd percentile (HP:0003561)3.84750347
5Abnormality of cells of the erythroid lineage (HP:0012130)3.81743999
6Volvulus (HP:0002580)3.79926623
7Aplastic anemia (HP:0001915)3.65411573
8Abnormal number of erythroid precursors (HP:0012131)3.56432373
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.34138539
10Meckel diverticulum (HP:0002245)3.28027345
11Abnormality of the preputium (HP:0100587)3.25986630
12Abnormal mitochondria in muscle tissue (HP:0008316)3.23919443
13Abnormality of the ileum (HP:0001549)3.11329427
14Type I transferrin isoform profile (HP:0003642)3.10117632
15Renal cortical cysts (HP:0000803)3.09822441
16Abnormality of the renal collecting system (HP:0004742)3.06066126
17Acute encephalopathy (HP:0006846)3.01406504
18Abnormality of chromosome stability (HP:0003220)2.98153896
19Duplicated collecting system (HP:0000081)2.92361350
20Bone marrow hypocellularity (HP:0005528)2.78541290
21Cerebral edema (HP:0002181)2.78030270
22Aplasia/Hypoplasia of the fovea (HP:0008060)2.71452482
23Hypoplasia of the fovea (HP:0007750)2.71452482
24Pallor (HP:0000980)2.68690724
25Severe visual impairment (HP:0001141)2.66599117
26Small intestinal stenosis (HP:0012848)2.59330247
27Duodenal stenosis (HP:0100867)2.59330247
28Hepatocellular necrosis (HP:0001404)2.57695130
29Clubbing of toes (HP:0100760)2.57471890
30Muscle fiber atrophy (HP:0100295)2.57208907
31Macrocytic anemia (HP:0001972)2.56373050
32Abnormality of DNA repair (HP:0003254)2.51644636
33Myelodysplasia (HP:0002863)2.51158256
34Colon cancer (HP:0003003)2.50372827
35Decreased activity of mitochondrial respiratory chain (HP:0008972)2.47611873
36Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.47611873
37Cerebral hypomyelination (HP:0006808)2.45586327
38Type 2 muscle fiber atrophy (HP:0003554)2.45335407
39Supernumerary spleens (HP:0009799)2.44868667
40Patellar aplasia (HP:0006443)2.44118723
41Progressive macrocephaly (HP:0004481)2.42481424
42Abnormality of the fovea (HP:0000493)2.39011557
43Intestinal atresia (HP:0011100)2.37530739
44Ectopic kidney (HP:0000086)2.36667654
45Increased hepatocellular lipid droplets (HP:0006565)2.36655643
46Premature graying of hair (HP:0002216)2.36339019
47Breast hypoplasia (HP:0003187)2.33221343
48Absent thumb (HP:0009777)2.32262220
49Asplenia (HP:0001746)2.32178555
50Exertional dyspnea (HP:0002875)2.29699233
51Rough bone trabeculation (HP:0100670)2.27592499
52Abnormal lung lobation (HP:0002101)2.27240500
53Triphalangeal thumb (HP:0001199)2.26278590
54Aplasia/Hypoplasia of the patella (HP:0006498)2.24195526
55Nephroblastoma (Wilms tumor) (HP:0002667)2.22634830
56Lactic acidosis (HP:0003128)2.22295019
57Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.20997059
58Mitochondrial inheritance (HP:0001427)2.16264463
59Short tibia (HP:0005736)2.16021120
60Aplasia/Hypoplasia of the tibia (HP:0005772)2.15552250
61Embryonal renal neoplasm (HP:0011794)2.14931769
62Pancreatic cysts (HP:0001737)2.14254983
63Short middle phalanx of the 5th finger (HP:0004220)2.13186791
64Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.12937077
65Abnormality of midbrain morphology (HP:0002418)2.12677085
66Molar tooth sign on MRI (HP:0002419)2.12677085
67Abnormality of the duodenum (HP:0002246)2.12429596
68Absent radius (HP:0003974)2.12272607
69Aplasia/Hypoplasia of the spleen (HP:0010451)2.12257109
70Microvesicular hepatic steatosis (HP:0001414)2.11522086
71Aplasia/Hypoplasia of the sacrum (HP:0008517)2.11396153
72Lymphoma (HP:0002665)2.11276212
73IgM deficiency (HP:0002850)2.08672382
74Glioma (HP:0009733)2.08280559
75Increased intramyocellular lipid droplets (HP:0012240)2.06488519
76Stenosis of the external auditory canal (HP:0000402)2.05542518
77Pancytopenia (HP:0001876)2.00176637
78Poikiloderma (HP:0001029)1.99647772
79Agnosia (HP:0010524)1.98844192
80Abnormality of the pons (HP:0007361)1.98831495
81Aplasia involving forearm bones (HP:0009822)1.96563337
82Absent forearm bone (HP:0003953)1.96563337
83Sloping forehead (HP:0000340)1.96236275
84Oral leukoplakia (HP:0002745)1.95996358
85Severe combined immunodeficiency (HP:0004430)1.93662674
86Horseshoe kidney (HP:0000085)1.93387655
87Cutaneous melanoma (HP:0012056)1.91654699
88Capillary hemangiomas (HP:0005306)1.91368598
89Squamous cell carcinoma (HP:0002860)1.89635945
90Abnormality of methionine metabolism (HP:0010901)1.89130642
91Abnormality of alanine metabolism (HP:0010916)1.88905917
92Hyperalaninemia (HP:0003348)1.88905917
93Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.88905917
94Astrocytoma (HP:0009592)1.88556121
95Abnormality of the astrocytes (HP:0100707)1.88556121
96Abnormal number of incisors (HP:0011064)1.88551816
97IgG deficiency (HP:0004315)1.88541445
98Combined immunodeficiency (HP:0005387)1.87836210
99Short thumb (HP:0009778)1.87759981
100Bifid tongue (HP:0010297)1.87605069
101Acute necrotizing encephalopathy (HP:0006965)1.87529971
102Tracheoesophageal fistula (HP:0002575)1.87394308
103Leukopenia (HP:0001882)1.87008295
104Abnormal protein glycosylation (HP:0012346)1.86719265
105Abnormal glycosylation (HP:0012345)1.86719265
106Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.86719265
107Abnormal protein N-linked glycosylation (HP:0012347)1.86719265
108Increased CSF lactate (HP:0002490)1.86211969
109Hypoplasia of the pons (HP:0012110)1.85810908
110Hepatic necrosis (HP:0002605)1.85626315
111Elevated erythrocyte sedimentation rate (HP:0003565)1.85054068
112Sensory axonal neuropathy (HP:0003390)1.83596240
113Rhabdomyosarcoma (HP:0002859)1.83343937
114Petechiae (HP:0000967)1.82629169
115Tubulointerstitial nephritis (HP:0001970)1.81299606
116Oligodactyly (hands) (HP:0001180)1.80311449
117Prostate neoplasm (HP:0100787)1.79067207
118Abnormality of the renal cortex (HP:0011035)1.78777915
119Reduced antithrombin III activity (HP:0001976)1.78138129
120Increased serum lactate (HP:0002151)1.77396235
121Cellular immunodeficiency (HP:0005374)1.77198974
122Septo-optic dysplasia (HP:0100842)1.76237080
123Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.75867190
124Abnormality of the carotid arteries (HP:0005344)1.75603254
125Entropion (HP:0000621)1.75492328
126Acute lymphatic leukemia (HP:0006721)1.75375407
127Methylmalonic acidemia (HP:0002912)1.74187885
128Absent rod-and cone-mediated responses on ERG (HP:0007688)1.73303969
129Abnormal trabecular bone morphology (HP:0100671)1.73233214
1303-Methylglutaconic aciduria (HP:0003535)1.72728775
13111 pairs of ribs (HP:0000878)1.72614260
132Gastrointestinal atresia (HP:0002589)1.72596460
133Abnormality of the heme biosynthetic pathway (HP:0010472)1.72287057
134Optic nerve coloboma (HP:0000588)1.72159928
135Rib fusion (HP:0000902)1.71699202
136Retrobulbar optic neuritis (HP:0100654)1.71310243
137Optic neuritis (HP:0100653)1.71310243
138Aplasia/Hypoplasia of the macula (HP:0008059)1.69784699
139Medulloblastoma (HP:0002885)1.69282508
140Carpal bone hypoplasia (HP:0001498)1.68957804
141Neoplasm of the colon (HP:0100273)1.68858247
142Dry hair (HP:0011359)1.68844611
143Nephronophthisis (HP:0000090)1.68543751
144Selective tooth agenesis (HP:0001592)1.68185130
145Lipid accumulation in hepatocytes (HP:0006561)1.67880097
146Degeneration of anterior horn cells (HP:0002398)1.67834017
147Abnormality of the anterior horn cell (HP:0006802)1.67834017
148Chronic hepatic failure (HP:0100626)1.67090024
149Acute myeloid leukemia (HP:0004808)1.66456095
150Ependymoma (HP:0002888)1.66212458
151Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.65857098

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.37711352
2WEE13.32301124
3NME23.08865967
4SRPK12.98697198
5STK162.95586754
6PLK42.91974698
7EIF2AK12.86494735
8MKNK12.83721642
9CDC72.68312722
10PIM22.64243958
11VRK12.52940569
12MKNK22.43597399
13VRK22.39900147
14ACVR1B2.02135632
15TNIK2.00175675
16SCYL21.98981576
17NME11.98144295
18CASK1.97090543
19EIF2AK31.92875471
20BRSK21.89047964
21NUAK11.78361575
22PLK11.69368316
23MAPK131.55958644
24PDK21.53941162
25TLK11.48869211
26ARAF1.47971025
27ERBB31.46626105
28KIT1.43702104
29CDK71.42840557
30ZAK1.35672012
31PBK1.35594747
32CSNK1G11.33515988
33CLK11.32590767
34MAP3K41.31304806
35DYRK31.30452124
36BLK1.29267042
37NEK11.28629542
38ATR1.27044816
39PLK31.26105845
40BCKDK1.24586306
41CSNK1A1L1.23240965
42TSSK61.23073751
43PIK3CG1.22957541
44BRAF1.21893908
45TXK1.20850960
46EIF2AK21.19278526
47WNK31.18327437
48CHEK21.17653572
49TTK1.17234762
50AURKB1.17042074
51NEK21.16931763
52CSNK1G21.16922392
53PNCK1.15651634
54TAF11.15013410
55IRAK41.11686036
56CCNB11.10105683
57MUSK1.09572099
58MARK31.05831698
59PLK21.05351745
60TESK21.02758660
61TGFBR10.99893036
62MAP4K20.99778509
63TIE10.96559529
64YES10.96444788
65BMPR1B0.94640451
66AURKA0.94540494
67RPS6KA40.92860718
68PASK0.91613718
69MAP3K140.89825865
70TEC0.87886136
71PIM10.85684488
72FRK0.81683946
73ADRBK20.80511594
74MAP2K30.80323142
75MAP2K70.80291711
76TAOK20.80011908
77STK40.78715973
78BRSK10.78422369
79STK38L0.78413506
80CHEK10.78151974
81RIPK40.77953347
82RPS6KB20.76740509
83CSNK2A10.71835029
84LYN0.70399799
85LATS10.70329824
86BTK0.70158391
87IKBKB0.69929591
88CDK80.69247118
89ATM0.68204935
90CDK40.67878795
91CDK190.67164226
92KDR0.65352364
93PTK2B0.65100608
94BMPR20.64623474
95OBSCN0.64413324
96NLK0.64387416
97CSNK2A20.63372456
98CDK30.61609686
99DYRK20.61362021
100RPS6KA50.60720352
101MAPKAPK50.59422532
102MATK0.58804822
103FLT30.58351751
104MAPKAPK30.55884552
105MAP4K10.55466281
106BCR0.52841568
107HIPK20.52226665
108TAOK30.51851081
109PRKCQ0.51572930
110STK30.51330971
111MAP3K80.51230842
112MAP3K120.50638436
113IRAK30.49450586
114SIK30.49165351
115CSNK1G30.48860688
116PAK10.48776950
117SYK0.48731159
118MST40.44537057
119CSF1R0.43394911
120NEK60.43358315
121PRKCI0.42718884
122LCK0.42365096
123STK240.42260553
124CDK20.40478984
125CDK10.40424800
126GRK70.40345208
127RPS6KA60.39538376
128RPS6KL10.38107290
129RPS6KC10.38107290
130RAF10.37374445
131MAP3K110.36449921
132STK100.35936211
133CDK120.35864736
134CSNK1E0.35448283
135ZAP700.34355418
136CDK60.34138506
137BRD40.33871562
138PRKACB0.33807412
139INSRR0.33763496
140MAP3K60.33129416
141MAP3K100.32999038
142PRKCE0.32997008
143GRK10.32013352

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.36622405
2Ribosome_Homo sapiens_hsa030103.65230692
3Mismatch repair_Homo sapiens_hsa034303.62481699
4RNA polymerase_Homo sapiens_hsa030203.39389341
5Proteasome_Homo sapiens_hsa030503.28722884
6Homologous recombination_Homo sapiens_hsa034403.16041744
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.10346582
8Base excision repair_Homo sapiens_hsa034102.81818860
9Nucleotide excision repair_Homo sapiens_hsa034202.78924478
10Spliceosome_Homo sapiens_hsa030402.78336368
11Fanconi anemia pathway_Homo sapiens_hsa034602.60157099
12Pyrimidine metabolism_Homo sapiens_hsa002402.36358409
13Non-homologous end-joining_Homo sapiens_hsa034502.30536527
14Protein export_Homo sapiens_hsa030602.25622024
15RNA transport_Homo sapiens_hsa030132.24823827
16Cell cycle_Homo sapiens_hsa041102.12519755
17Basal transcription factors_Homo sapiens_hsa030222.04178423
18Cysteine and methionine metabolism_Homo sapiens_hsa002701.97407951
19RNA degradation_Homo sapiens_hsa030181.91966902
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.83686370
21Selenocompound metabolism_Homo sapiens_hsa004501.57695483
22One carbon pool by folate_Homo sapiens_hsa006701.51315585
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.46859691
24Propanoate metabolism_Homo sapiens_hsa006401.41341992
25Purine metabolism_Homo sapiens_hsa002301.39865802
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.30180452
27p53 signaling pathway_Homo sapiens_hsa041151.24571179
28Oxidative phosphorylation_Homo sapiens_hsa001901.21962386
29Epstein-Barr virus infection_Homo sapiens_hsa051691.16469444
30Parkinsons disease_Homo sapiens_hsa050121.16244649
31Huntingtons disease_Homo sapiens_hsa050161.16117895
32mRNA surveillance pathway_Homo sapiens_hsa030151.15049206
33Pyruvate metabolism_Homo sapiens_hsa006201.06613287
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.06141815
35Primary immunodeficiency_Homo sapiens_hsa053401.03639612
36Herpes simplex infection_Homo sapiens_hsa051680.96857709
37Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96169765
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90973275
39Fatty acid elongation_Homo sapiens_hsa000620.88629989
40Allograft rejection_Homo sapiens_hsa053300.80606935
41Hematopoietic cell lineage_Homo sapiens_hsa046400.79724140
42NF-kappa B signaling pathway_Homo sapiens_hsa040640.76800847
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.76686161
44Measles_Homo sapiens_hsa051620.75068915
45Vitamin B6 metabolism_Homo sapiens_hsa007500.75036595
46Sulfur relay system_Homo sapiens_hsa041220.73287276
47Graft-versus-host disease_Homo sapiens_hsa053320.72727031
48Intestinal immune network for IgA production_Homo sapiens_hsa046720.71718231
49Malaria_Homo sapiens_hsa051440.71220533
50Arachidonic acid metabolism_Homo sapiens_hsa005900.66868556
51Antigen processing and presentation_Homo sapiens_hsa046120.66854050
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.66594431
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66228488
54Asthma_Homo sapiens_hsa053100.65760156
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65720260
56Biosynthesis of amino acids_Homo sapiens_hsa012300.65681547
57Alzheimers disease_Homo sapiens_hsa050100.64696161
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64267697
59Systemic lupus erythematosus_Homo sapiens_hsa053220.63524359
60Folate biosynthesis_Homo sapiens_hsa007900.63063847
61Cardiac muscle contraction_Homo sapiens_hsa042600.62750546
62Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.62581171
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.62495752
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61296760
65Viral carcinogenesis_Homo sapiens_hsa052030.60586422
66Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60025102
67Autoimmune thyroid disease_Homo sapiens_hsa053200.59665347
68N-Glycan biosynthesis_Homo sapiens_hsa005100.55995895
69HTLV-I infection_Homo sapiens_hsa051660.55095280
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55054733
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54428183
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.53703422
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52611867
74Legionellosis_Homo sapiens_hsa051340.51724630
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51617355
76Peroxisome_Homo sapiens_hsa041460.51306668
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50073790
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.48618779
79Rheumatoid arthritis_Homo sapiens_hsa053230.46515311
80Oocyte meiosis_Homo sapiens_hsa041140.44194980
81Nitrogen metabolism_Homo sapiens_hsa009100.42662323
82Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.42489613
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42475784
84Leishmaniasis_Homo sapiens_hsa051400.41851211
85Apoptosis_Homo sapiens_hsa042100.41493277
86Olfactory transduction_Homo sapiens_hsa047400.41431876
87Carbon metabolism_Homo sapiens_hsa012000.41411057
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.40773675
89RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.39602502
90Hepatitis B_Homo sapiens_hsa051610.38933123
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38841038
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38293492
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38179701
94Influenza A_Homo sapiens_hsa051640.37805382
95Steroid biosynthesis_Homo sapiens_hsa001000.37604159
96Sphingolipid metabolism_Homo sapiens_hsa006000.36954039
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.36753634
98Fatty acid metabolism_Homo sapiens_hsa012120.36359960
99Butanoate metabolism_Homo sapiens_hsa006500.35813827
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.34408993
101Ether lipid metabolism_Homo sapiens_hsa005650.33727154
102Jak-STAT signaling pathway_Homo sapiens_hsa046300.32635451
103Glutathione metabolism_Homo sapiens_hsa004800.31847329
104Alcoholism_Homo sapiens_hsa050340.30623239
105MicroRNAs in cancer_Homo sapiens_hsa052060.28215498
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.27903469
107Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27748369
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27520703
109Small cell lung cancer_Homo sapiens_hsa052220.27434360
110Shigellosis_Homo sapiens_hsa051310.26908622
111Lysine degradation_Homo sapiens_hsa003100.26267646
112Basal cell carcinoma_Homo sapiens_hsa052170.26125083
113Thyroid cancer_Homo sapiens_hsa052160.25659155
114Taste transduction_Homo sapiens_hsa047420.25602888
115Phototransduction_Homo sapiens_hsa047440.25509827
116Type I diabetes mellitus_Homo sapiens_hsa049400.25329450
117B cell receptor signaling pathway_Homo sapiens_hsa046620.25107874
118Pathways in cancer_Homo sapiens_hsa052000.24000733
119Linoleic acid metabolism_Homo sapiens_hsa005910.23540525
120Melanoma_Homo sapiens_hsa052180.22297215
121Metabolic pathways_Homo sapiens_hsa011000.22243558
122Viral myocarditis_Homo sapiens_hsa054160.22068425
123Colorectal cancer_Homo sapiens_hsa052100.21218150
124Tryptophan metabolism_Homo sapiens_hsa003800.21018152
125Regulation of autophagy_Homo sapiens_hsa041400.20273248
126Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.19997493
127Phagosome_Homo sapiens_hsa041450.19921477
128Pertussis_Homo sapiens_hsa051330.19819937
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.19585049
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.18785881
131TGF-beta signaling pathway_Homo sapiens_hsa043500.17352986
1322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.17332357
133Steroid hormone biosynthesis_Homo sapiens_hsa001400.16264073
134Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.15186496
135Arginine and proline metabolism_Homo sapiens_hsa003300.15068599
136alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.14092763
137Pentose phosphate pathway_Homo sapiens_hsa000300.12322223
138Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.10238547
139Pentose and glucuronate interconversions_Homo sapiens_hsa000400.05624363
140Chemical carcinogenesis_Homo sapiens_hsa052040.05105112
141Vitamin digestion and absorption_Homo sapiens_hsa049770.04235361
142Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.01522310

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