WDR75

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)4.92487453
2nuclear pore complex assembly (GO:0051292)4.74717304
3DNA unwinding involved in DNA replication (GO:0006268)4.64378670
4mitotic metaphase plate congression (GO:0007080)4.59497518
5nucleobase biosynthetic process (GO:0046112)4.56191383
6maturation of SSU-rRNA (GO:0030490)4.55760110
7DNA replication initiation (GO:0006270)4.52705766
8protein localization to kinetochore (GO:0034501)4.47040932
9formation of translation preinitiation complex (GO:0001731)4.42163055
10mitotic nuclear envelope disassembly (GO:0007077)4.36747674
11purine nucleobase biosynthetic process (GO:0009113)4.31076573
12IMP biosynthetic process (GO:0006188)4.28866100
13ribosome assembly (GO:0042255)4.25476808
14DNA strand elongation involved in DNA replication (GO:0006271)4.22306776
15membrane disassembly (GO:0030397)4.09396819
16nuclear envelope disassembly (GO:0051081)4.09396819
17folic acid-containing compound biosynthetic process (GO:0009396)4.07292930
18metaphase plate congression (GO:0051310)4.06362406
19ribosome biogenesis (GO:0042254)4.05657189
20regulation of centriole replication (GO:0046599)4.03700239
21DNA strand elongation (GO:0022616)4.01587491
22DNA double-strand break processing (GO:0000729)3.99130356
23DNA replication checkpoint (GO:0000076)3.97650469
24DNA replication-dependent nucleosome assembly (GO:0006335)3.97048996
25DNA replication-dependent nucleosome organization (GO:0034723)3.97048996
26IMP metabolic process (GO:0046040)3.85166330
27chromatin remodeling at centromere (GO:0031055)3.82841295
28non-recombinational repair (GO:0000726)3.81518839
29double-strand break repair via nonhomologous end joining (GO:0006303)3.81518839
30ribosomal large subunit biogenesis (GO:0042273)3.79328977
31CENP-A containing nucleosome assembly (GO:0034080)3.78746586
32telomere maintenance via semi-conservative replication (GO:0032201)3.78131198
33ribonucleoprotein complex biogenesis (GO:0022613)3.77889561
34protein localization to chromosome, centromeric region (GO:0071459)3.75906093
35ribosomal small subunit assembly (GO:0000028)3.71250475
36proteasome assembly (GO:0043248)3.69338395
37regulation of spindle organization (GO:0090224)3.65387263
38establishment of chromosome localization (GO:0051303)3.63974754
39pore complex assembly (GO:0046931)3.63565512
40kinetochore organization (GO:0051383)3.62891940
41establishment of viral latency (GO:0019043)3.56835769
42attachment of spindle microtubules to kinetochore (GO:0008608)3.55040169
43mitotic sister chromatid segregation (GO:0000070)3.54297101
44DNA replication-independent nucleosome assembly (GO:0006336)3.52440595
45DNA replication-independent nucleosome organization (GO:0034724)3.52440595
46rRNA processing (GO:0006364)3.50119933
47mitotic chromosome condensation (GO:0007076)3.48746785
48tRNA aminoacylation for protein translation (GO:0006418)3.48532895
49DNA ligation (GO:0006266)3.48129856
50tRNA aminoacylation (GO:0043039)3.45160853
51amino acid activation (GO:0043038)3.45160853
52telomere maintenance via recombination (GO:0000722)3.44406811
53mitotic recombination (GO:0006312)3.42259471
54DNA duplex unwinding (GO:0032508)3.40788404
55rRNA metabolic process (GO:0016072)3.39550159
56DNA geometric change (GO:0032392)3.39435925
57spindle checkpoint (GO:0031577)3.37592298
58spliceosomal snRNP assembly (GO:0000387)3.37133493
59negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.36692288
60sister chromatid segregation (GO:0000819)3.35504811
61negative regulation of DNA-dependent DNA replication (GO:2000104)3.33702027
62negative regulation of chromosome segregation (GO:0051985)3.32989187
63regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.32633336
64regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.32328751
65translational termination (GO:0006415)3.32210211
66spindle assembly checkpoint (GO:0071173)3.31791128
67histone exchange (GO:0043486)3.31499279
68regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.31436430
69negative regulation of mitotic sister chromatid separation (GO:2000816)3.30728885
70negative regulation of mitotic sister chromatid segregation (GO:0033048)3.30728885
71negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.30728885
72negative regulation of sister chromatid segregation (GO:0033046)3.30728885
73rRNA methylation (GO:0031167)3.29282798
74translational initiation (GO:0006413)3.28522993
75mitotic spindle checkpoint (GO:0071174)3.27990735
76mitotic spindle assembly checkpoint (GO:0007094)3.27903503
77telomere maintenance via telomere lengthening (GO:0010833)3.25813448
78viral transcription (GO:0019083)3.25745826
79regulation of mitotic spindle organization (GO:0060236)3.25691483
80negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.21379946
81ribosomal small subunit biogenesis (GO:0042274)3.20781673
82rRNA modification (GO:0000154)3.20647816
83anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.20254376
84kinetochore assembly (GO:0051382)3.19673973
85somatic hypermutation of immunoglobulin genes (GO:0016446)3.19416680
86somatic diversification of immune receptors via somatic mutation (GO:0002566)3.19416680
87regulation of posttranscriptional gene silencing (GO:0060147)3.18710202
88regulation of gene silencing by miRNA (GO:0060964)3.18710202
89regulation of gene silencing by RNA (GO:0060966)3.18710202
90regulation of centrosome cycle (GO:0046605)3.18288336
91positive regulation of chromosome segregation (GO:0051984)3.18128216
92regulation of mitotic metaphase/anaphase transition (GO:0030071)3.17383344
93DNA topological change (GO:0006265)3.17180389
94regulation of chromosome segregation (GO:0051983)3.16805499
95regulation of translational fidelity (GO:0006450)3.14013527
96DNA catabolic process, exonucleolytic (GO:0000738)3.13590031
97regulation of helicase activity (GO:0051095)3.13350070
98nuclear envelope organization (GO:0006998)3.13129554
99histone mRNA metabolic process (GO:0008334)3.12327520
100negative regulation of DNA recombination (GO:0045910)3.12173725
101regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.10462471
102mitochondrial RNA metabolic process (GO:0000959)3.07359340
103negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.05366268
104negative regulation of ligase activity (GO:0051352)3.05366268
105positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.05264392
106somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.04945639
107somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.04945639
108isotype switching (GO:0045190)3.04945639
109translational elongation (GO:0006414)3.04773662
110synapsis (GO:0007129)3.04576542
111spliceosomal complex assembly (GO:0000245)3.04066458
112regulation of sister chromatid segregation (GO:0033045)3.03726859
113regulation of mitotic sister chromatid separation (GO:0010965)3.03726859
114regulation of mitotic sister chromatid segregation (GO:0033047)3.03726859
115nucleotide-excision repair, DNA gap filling (GO:0006297)3.02777946
116protein K6-linked ubiquitination (GO:0085020)3.02714863
117nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.02553077
118DNA damage response, detection of DNA damage (GO:0042769)3.02056886
119regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.01737734
120regulation of mitotic spindle checkpoint (GO:1903504)3.01737734
121regulation of translational termination (GO:0006449)3.01490705
122establishment of integrated proviral latency (GO:0075713)3.00621339
123mitotic sister chromatid cohesion (GO:0007064)3.00529218
124regulation of histone H3-K9 methylation (GO:0051570)3.00171718
125RNA splicing, via transesterification reactions (GO:0000375)2.98695175
126somatic recombination of immunoglobulin gene segments (GO:0016447)2.97672359
127chromatin assembly or disassembly (GO:0006333)2.96942627
128RNA-dependent DNA replication (GO:0006278)2.96785152
129maturation of 5.8S rRNA (GO:0000460)2.96424746
130transcription elongation from RNA polymerase I promoter (GO:0006362)2.96366128
131mRNA splicing, via spliceosome (GO:0000398)2.96016769
132RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.96016769
133folic acid metabolic process (GO:0046655)2.94089906
134pseudouridine synthesis (GO:0001522)2.94034008

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.14886335
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.64386542
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.12730484
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.93567706
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.40468847
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.27046110
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.16528562
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.02018106
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.00798606
10* EST1_17652178_ChIP-ChIP_JURKAT_Human2.97331579
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.80399111
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.78749230
13* ETS1_20019798_ChIP-Seq_JURKAT_Human2.71896186
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.61049883
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.59984678
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.57711315
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.37613870
18* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.35255037
19XRN2_22483619_ChIP-Seq_HELA_Human2.35126543
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.34342619
21AR_21909140_ChIP-Seq_LNCAP_Human2.29514862
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.25017226
23* VDR_23849224_ChIP-Seq_CD4+_Human2.22959473
24E2F1_21310950_ChIP-Seq_MCF-7_Human2.13322752
25EGR1_19374776_ChIP-ChIP_THP-1_Human2.10219038
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.09503732
27MYCN_18555785_ChIP-Seq_MESCs_Mouse2.04678906
28* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.98490698
29E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.95071805
30FOXP3_21729870_ChIP-Seq_TREG_Human1.94917042
31DCP1A_22483619_ChIP-Seq_HELA_Human1.93773375
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.89620608
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.89006299
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.87577062
35TTF2_22483619_ChIP-Seq_HELA_Human1.85572259
36GABP_19822575_ChIP-Seq_HepG2_Human1.81386860
37* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80394257
38* ELK1_19687146_ChIP-ChIP_HELA_Human1.79490989
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.75511675
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.73819619
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.71954426
42NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.71701926
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.67718731
44* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.61245953
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.58653793
46CIITA_25753668_ChIP-Seq_RAJI_Human1.57061535
47ELF1_17652178_ChIP-ChIP_JURKAT_Human1.56555157
48* FLI1_27457419_Chip-Seq_LIVER_Mouse1.55748903
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54731335
50EWS_26573619_Chip-Seq_HEK293_Human1.53919811
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52235567
52KDM5A_27292631_Chip-Seq_BREAST_Human1.50218207
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47021826
54* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45508146
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.43645581
56SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.43018637
57POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.41696978
58MYC_22102868_ChIP-Seq_BL_Human1.39296561
59DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.38981498
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38460141
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.37619320
62* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.36980769
63* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33176905
64STAT3_1855785_ChIP-Seq_MESCs_Mouse1.33167221
65FUS_26573619_Chip-Seq_HEK293_Human1.33136080
66* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31312569
67TP63_19390658_ChIP-ChIP_HaCaT_Human1.26440796
68TFEB_21752829_ChIP-Seq_HELA_Human1.23988312
69KLF4_18555785_ChIP-Seq_MESCs_Mouse1.22225178
70ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21091594
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.20376620
72* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18759298
73* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18736155
74SRF_21415370_ChIP-Seq_HL-1_Mouse1.16130502
75* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.14277375
76ZNF274_21170338_ChIP-Seq_K562_Hela1.13703079
77NANOG_16153702_ChIP-ChIP_HESCs_Human1.11533487
78SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.10710030
79KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10145587
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09893886
81* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09814857
82CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.08107742
83ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07638706
84KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.07361095
85KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.07361095
86KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.07361095
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.07244569
88HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04689891
89* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04021098
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03408587
91* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01953971
92MYC_18940864_ChIP-ChIP_HL60_Human1.01817561
93ESR1_15608294_ChIP-ChIP_MCF-7_Human1.00064188
94CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.99706883
95IRF1_19129219_ChIP-ChIP_H3396_Human0.99009610
96* SOX17_20123909_ChIP-Seq_XEN_Mouse0.98203172
97TCF3_18692474_ChIP-Seq_MEFs_Mouse0.97336034
98POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96557080
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.93028716
100SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.92772032
101CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.92644962
102POU5F1_16153702_ChIP-ChIP_HESCs_Human0.91692791
103SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.90947206
104NANOG_21062744_ChIP-ChIP_HESCs_Human0.90715101
105NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.90216564
106ELK1_22589737_ChIP-Seq_MCF10A_Human0.89882343
107KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.88737359
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.88289492
109CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87833515
110* PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87758180
111* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.87009646
112HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84713568
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.83831423
114TAF15_26573619_Chip-Seq_HEK293_Human0.83095484
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82718705
116NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.81785282
117IGF1R_20145208_ChIP-Seq_DFB_Human0.78818230
118TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.77569686
119* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77367128
120VDR_22108803_ChIP-Seq_LS180_Human0.75274340
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.71911039
122* SUZ12_27294783_Chip-Seq_NPCs_Mouse0.71197222
123* EZH2_27294783_Chip-Seq_NPCs_Mouse0.64918595

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.30899122
2MP0010094_abnormal_chromosome_stability4.91831654
3MP0004957_abnormal_blastocyst_morpholog4.77670941
4MP0003111_abnormal_nucleus_morphology4.53828569
5MP0008057_abnormal_DNA_replication4.21922072
6MP0003077_abnormal_cell_cycle4.16078554
7MP0008058_abnormal_DNA_repair3.53481501
8MP0003123_paternal_imprinting2.97885196
9MP0008007_abnormal_cellular_replicative2.86627769
10MP0009697_abnormal_copulation2.76906495
11MP0008932_abnormal_embryonic_tissue2.72183047
12MP0001730_embryonic_growth_arrest2.67278200
13MP0008877_abnormal_DNA_methylation2.61050730
14MP0010352_gastrointestinal_tract_polyps2.53700385
15MP0000350_abnormal_cell_proliferation2.44593631
16MP0010307_abnormal_tumor_latency2.25545411
17MP0002396_abnormal_hematopoietic_system2.17331454
18MP0003786_premature_aging2.16687605
19MP0001672_abnormal_embryogenesis/_devel2.00125719
20MP0005380_embryogenesis_phenotype2.00125719
21MP0001697_abnormal_embryo_size1.92158749
22MP0003984_embryonic_growth_retardation1.81414831
23MP0002088_abnormal_embryonic_growth/wei1.76875439
24MP0002080_prenatal_lethality1.72538241
25MP0002085_abnormal_embryonic_tissue1.71959859
26MP0002084_abnormal_developmental_patter1.71241841
27MP0002254_reproductive_system_inflammat1.68167173
28MP0003718_maternal_effect1.67807717
29MP0003121_genomic_imprinting1.66290511
30MP0004197_abnormal_fetal_growth/weight/1.62260617
31MP0003567_abnormal_fetal_cardiomyocyte1.61283803
32MP0002086_abnormal_extraembryonic_tissu1.60140579
33MP0006035_abnormal_mitochondrial_morpho1.60031166
34MP0003950_abnormal_plasma_membrane1.57500585
35MP0000490_abnormal_crypts_of1.52744303
36MP0008789_abnormal_olfactory_epithelium1.45366058
37MP0003890_abnormal_embryonic-extraembry1.42426550
38MP0004808_abnormal_hematopoietic_stem1.42377613
39MP0000313_abnormal_cell_death1.41643305
40MP0002210_abnormal_sex_determination1.39414193
41MP0001293_anophthalmia1.37809498
42MP0003806_abnormal_nucleotide_metabolis1.32692013
43MP0002019_abnormal_tumor_incidence1.30435147
44MP0006072_abnormal_retinal_apoptosis1.27965700
45MP0001145_abnormal_male_reproductive1.25145190
46MP0010030_abnormal_orbit_morphology1.22881829
47MP0005076_abnormal_cell_differentiation1.16702932
48MP0000537_abnormal_urethra_morphology1.14533322
49MP0002233_abnormal_nose_morphology1.11364454
50MP0008995_early_reproductive_senescence1.10585519
51MP0004147_increased_porphyrin_level1.09129736
52MP0010234_abnormal_vibrissa_follicle1.08702040
53MP0000653_abnormal_sex_gland1.07771595
54MP0003119_abnormal_digestive_system1.04989651
55MP0001929_abnormal_gametogenesis1.04190632
56MP0005499_abnormal_olfactory_system1.04057527
57MP0005394_taste/olfaction_phenotype1.04057527
58MP0002160_abnormal_reproductive_system0.99085629
59MP0003937_abnormal_limbs/digits/tail_de0.98182578
60MP0002102_abnormal_ear_morphology0.95882138
61MP0009672_abnormal_birth_weight0.95484188
62MP0003315_abnormal_perineum_morphology0.94127808
63MP0002009_preneoplasia0.91487459
64MP0003941_abnormal_skin_development0.91222016
65MP0009333_abnormal_splenocyte_physiolog0.90739387
66MP0004133_heterotaxia0.90467345
67MP0001545_abnormal_hematopoietic_system0.89827664
68MP0005397_hematopoietic_system_phenotyp0.89827664
69MP0000703_abnormal_thymus_morphology0.89212646
70MP0002751_abnormal_autonomic_nervous0.89067049
71MP0000358_abnormal_cell_content/0.88687193
72MP0005384_cellular_phenotype0.88096208
73MP0004264_abnormal_extraembryonic_tissu0.87339104
74MP0002111_abnormal_tail_morphology0.85980233
75MP0009703_decreased_birth_body0.85661466
76MP0003221_abnormal_cardiomyocyte_apopto0.84324854
77MP0009053_abnormal_anal_canal0.84290000
78MP0003705_abnormal_hypodermis_morpholog0.83346014
79MP0005621_abnormal_cell_physiology0.83295953
80MP0006054_spinal_hemorrhage0.80266426
81MP0001915_intracranial_hemorrhage0.79904248
82MP0005389_reproductive_system_phenotype0.79453700
83MP0001661_extended_life_span0.79396557
84MP0006292_abnormal_olfactory_placode0.79178265
85MP0002796_impaired_skin_barrier0.78979428
86MP0000428_abnormal_craniofacial_morphol0.77863472
87MP0003566_abnormal_cell_adhesion0.77771960
88MP0005395_other_phenotype0.77730608
89MP0000647_abnormal_sebaceous_gland0.77536506
90MP0003385_abnormal_body_wall0.77111375
91MP0005501_abnormal_skin_physiology0.76772292
92MP0006036_abnormal_mitochondrial_physio0.76347499
93MP0001119_abnormal_female_reproductive0.76230510
94MP0002653_abnormal_ependyma_morphology0.75728898
95MP0000372_irregular_coat_pigmentation0.74656988
96MP0005023_abnormal_wound_healing0.72710186
97MP0001286_abnormal_eye_development0.71651080
98MP0000432_abnormal_head_morphology0.71277877
99MP0002092_abnormal_eye_morphology0.71156067
100MP0003699_abnormal_female_reproductive0.71039924
101MP0010678_abnormal_skin_adnexa0.70737821
102MP0003763_abnormal_thymus_physiology0.69957252
103MP0001299_abnormal_eye_distance/0.69336932
104MP0002006_tumorigenesis0.68010785
105MP0002398_abnormal_bone_marrow0.66298754
106MP0002722_abnormal_immune_system0.66189612
107MP0001529_abnormal_vocalization0.64898357
108MP0001188_hyperpigmentation0.63078068
109MP0001177_atelectasis0.63049766
110MP0002161_abnormal_fertility/fecundity0.62090978
111MP0001849_ear_inflammation0.61380304
112MP0005220_abnormal_exocrine_pancreas0.60839509
113MP0001881_abnormal_mammary_gland0.60739911
114MP0000858_altered_metastatic_potential0.60042754
115MP0000689_abnormal_spleen_morphology0.59639158
116MP0003186_abnormal_redox_activity0.59611196
117MP0005391_vision/eye_phenotype0.59466886
118MP0003936_abnormal_reproductive_system0.59319221
119MP0002938_white_spotting0.58929526
120MP0000566_synostosis0.56725096
121MP0000579_abnormal_nail_morphology0.55998206
122MP0002697_abnormal_eye_size0.55558972
123MP0002877_abnormal_melanocyte_morpholog0.55265318
124MP0004233_abnormal_muscle_weight0.54601970
125MP0000477_abnormal_intestine_morphology0.53283038
126MP0002114_abnormal_axial_skeleton0.52453914
127MP0001853_heart_inflammation0.52254614
128MP0003861_abnormal_nervous_system0.51468152
129MP0000733_abnormal_muscle_development0.51278556
130MP0003755_abnormal_palate_morphology0.50853232
131MP0000627_abnormal_mammary_gland0.50801133
132MP0001919_abnormal_reproductive_system0.50751175
133MP0003935_abnormal_craniofacial_develop0.50588277
134MP0002925_abnormal_cardiovascular_devel0.49828021
135MP0003698_abnormal_male_reproductive0.48226189
136MP0000516_abnormal_urinary_system0.48151537

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.33552394
2Breast hypoplasia (HP:0003187)3.94541539
3Colon cancer (HP:0003003)3.91581089
4Reticulocytopenia (HP:0001896)3.84870498
5Chromsome breakage (HP:0040012)3.75069002
6Selective tooth agenesis (HP:0001592)3.68212212
7Medulloblastoma (HP:0002885)3.63280958
8Ependymoma (HP:0002888)3.61401188
9Abnormality of cells of the erythroid lineage (HP:0012130)3.47709994
10Abnormality of the labia minora (HP:0012880)3.37464600
11Chromosomal breakage induced by crosslinking agents (HP:0003221)3.33598677
12Abnormality of the anterior horn cell (HP:0006802)3.31632551
13Degeneration of anterior horn cells (HP:0002398)3.31632551
14Carpal bone hypoplasia (HP:0001498)3.22604387
15Abnormal number of erythroid precursors (HP:0012131)3.21011405
16Patellar aplasia (HP:0006443)3.16628991
17Oral leukoplakia (HP:0002745)3.16526810
18Abnormality of chromosome stability (HP:0003220)3.09127501
19Aplasia/Hypoplasia of the patella (HP:0006498)2.95175386
20Agnosia (HP:0010524)2.92425927
21Rough bone trabeculation (HP:0100670)2.92164891
22Rhabdomyosarcoma (HP:0002859)2.88378016
23Impulsivity (HP:0100710)2.83966850
24Abnormality of the preputium (HP:0100587)2.81718646
25Absent radius (HP:0003974)2.79961260
26Meckel diverticulum (HP:0002245)2.75172801
27Cerebral hypomyelination (HP:0006808)2.73367427
28Abnormality of the pons (HP:0007361)2.64993385
29Absent thumb (HP:0009777)2.61778501
30Abnormality of the carotid arteries (HP:0005344)2.61185127
31Abnormality of the ileum (HP:0001549)2.59772111
32Absent forearm bone (HP:0003953)2.59492193
33Aplasia involving forearm bones (HP:0009822)2.59492193
3411 pairs of ribs (HP:0000878)2.58041508
35Myelodysplasia (HP:0002863)2.55583597
36Proximal placement of thumb (HP:0009623)2.55451712
37Increased serum pyruvate (HP:0003542)2.54870354
38Aplastic anemia (HP:0001915)2.54769444
39Progressive external ophthalmoplegia (HP:0000590)2.54401912
40Deviation of the thumb (HP:0009603)2.54002620
41Basal cell carcinoma (HP:0002671)2.52136393
42Premature graying of hair (HP:0002216)2.50143156
43Neoplasm of the pancreas (HP:0002894)2.49895799
44Abnormality of glycolysis (HP:0004366)2.48338789
45Abnormal number of incisors (HP:0011064)2.46890505
46Abnormality of methionine metabolism (HP:0010901)2.44386485
47Aplasia/Hypoplasia of the uvula (HP:0010293)2.44339211
48Supernumerary spleens (HP:0009799)2.43826008
49Trismus (HP:0000211)2.43032871
50Macrocytic anemia (HP:0001972)2.41564705
51Microvesicular hepatic steatosis (HP:0001414)2.39620041
52Astrocytoma (HP:0009592)2.38372922
53Abnormality of the astrocytes (HP:0100707)2.38372922
54Clubbing of toes (HP:0100760)2.38357895
55Duodenal stenosis (HP:0100867)2.37929668
56Small intestinal stenosis (HP:0012848)2.37929668
57Pallor (HP:0000980)2.35308539
58Neoplasm of the oral cavity (HP:0100649)2.34837796
59Missing ribs (HP:0000921)2.34295720
60Glossoptosis (HP:0000162)2.32946155
61Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.31016230
62Glioma (HP:0009733)2.29905347
63Urethral obstruction (HP:0000796)2.29642775
64Hypoplasia of the pons (HP:0012110)2.28782585
65Sloping forehead (HP:0000340)2.28696329
66Biliary tract neoplasm (HP:0100574)2.27206820
67Neoplasm of striated muscle (HP:0009728)2.25021442
68Abnormal lung lobation (HP:0002101)2.24685437
69Horseshoe kidney (HP:0000085)2.23441302
70Facial hemangioma (HP:0000329)2.22364644
71Cortical dysplasia (HP:0002539)2.17804909
72Atresia of the external auditory canal (HP:0000413)2.17738737
73Ectopic kidney (HP:0000086)2.15746764
74Increased hepatocellular lipid droplets (HP:0006565)2.13246583
75Squamous cell carcinoma (HP:0002860)2.11282458
76Bifid tongue (HP:0010297)2.07939899
77Abnormal trabecular bone morphology (HP:0100671)2.07241868
78Choanal atresia (HP:0000453)2.05234845
79Bone marrow hypocellularity (HP:0005528)2.04595973
80Volvulus (HP:0002580)2.03713111
81Premature ovarian failure (HP:0008209)2.02965988
82Abnormality of aspartate family amino acid metabolism (HP:0010899)2.00944935
83Methylmalonic acidemia (HP:0002912)2.00852442
84Atrophy/Degeneration involving motor neurons (HP:0007373)2.00682149
85Cellular immunodeficiency (HP:0005374)1.99506056
86Cafe-au-lait spot (HP:0000957)1.98307078
87Abnormality of the duodenum (HP:0002246)1.98094658
88Abnormality of serum amino acid levels (HP:0003112)1.97979369
89Neoplasm of the colon (HP:0100273)1.97542785
90Irregular epiphyses (HP:0010582)1.96272744
91Tracheoesophageal fistula (HP:0002575)1.95718360
92Secondary amenorrhea (HP:0000869)1.95710330
93Spinal muscular atrophy (HP:0007269)1.95060836
94Amaurosis fugax (HP:0100576)1.95038307
95Aplasia/Hypoplasia of the sternum (HP:0006714)1.94890438
96CNS hypomyelination (HP:0003429)1.94525656
97Short thumb (HP:0009778)1.94225855
98Multiple enchondromatosis (HP:0005701)1.93173897
99Aplasia/hypoplasia of the humerus (HP:0006507)1.92734145
100Increased nuchal translucency (HP:0010880)1.92409932
101Slender long bone (HP:0003100)1.90925686
102Abnormality of the renal collecting system (HP:0004742)1.90115213
103Prominent nose (HP:0000448)1.89957284
104Acute encephalopathy (HP:0006846)1.89368557
105Postnatal microcephaly (HP:0005484)1.88851107
106Facial cleft (HP:0002006)1.86445860
107Microretrognathia (HP:0000308)1.85263285
108Nephroblastoma (Wilms tumor) (HP:0002667)1.85141151
109Pelvic girdle muscle weakness (HP:0003749)1.82908906
110Duplicated collecting system (HP:0000081)1.82818301
111Thrombocytosis (HP:0001894)1.81986184
112Neoplasm of the adrenal cortex (HP:0100641)1.81977329
113Hyperglycinemia (HP:0002154)1.81507770
114Clitoromegaly (HP:0000057)1.81057712
115Abnormality of the calcaneus (HP:0008364)1.80931146
116Triphalangeal thumb (HP:0001199)1.80663387
117Spastic diplegia (HP:0001264)1.79955829
118Embryonal renal neoplasm (HP:0011794)1.79299137
119Type I transferrin isoform profile (HP:0003642)1.78603797
120Lipid accumulation in hepatocytes (HP:0006561)1.78373289
121Ovarian neoplasm (HP:0100615)1.77545211
122Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.77323264
123Short 4th metacarpal (HP:0010044)1.77323264
124Neuroblastic tumors (HP:0004376)1.75909464
125Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.75909464
126Neuroblastoma (HP:0003006)1.75909464
127Primitive neuroectodermal tumor (HP:0030065)1.75909464
128Abnormality of homocysteine metabolism (HP:0010919)1.74956630
129Homocystinuria (HP:0002156)1.74956630
130Median cleft lip (HP:0000161)1.74309245
131Pancreatic islet-cell hyperplasia (HP:0004510)1.74045579
132Neoplasm of the adrenal gland (HP:0100631)1.73841821
133IgM deficiency (HP:0002850)1.73718102
134Freckling (HP:0001480)1.73282434
135Neoplasm of the small intestine (HP:0100833)1.72781118
136Shoulder girdle muscle weakness (HP:0003547)1.72509880
137Esophageal atresia (HP:0002032)1.72327054
138Abnormal spermatogenesis (HP:0008669)1.72296125
139Stenosis of the external auditory canal (HP:0000402)1.71525885
140Lymphoma (HP:0002665)1.71458021
141Breast carcinoma (HP:0003002)1.70757462
142Arteriovenous malformation (HP:0100026)1.70507400
143Increased serum lactate (HP:0002151)1.69984138
144Reduced antithrombin III activity (HP:0001976)1.69887249
145Deep philtrum (HP:0002002)1.68579659
146Capillary hemangiomas (HP:0005306)1.67580147
147Acute myeloid leukemia (HP:0004808)1.66110757
148Uterine neoplasm (HP:0010784)1.64993393
149Abnormality of DNA repair (HP:0003254)1.64796457
150Abnormality of the septum pellucidum (HP:0007375)1.62816430

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.52849838
2BUB14.52677572
3WEE14.23673058
4EIF2AK13.32952463
5TSSK63.04305654
6SRPK12.89032181
7NEK22.61294059
8ACVR1B2.58403563
9TTK2.53448507
10NEK12.28833938
11MKNK12.24230863
12BRSK22.15063172
13PLK12.12927559
14CDK122.10494198
15PASK2.06210914
16PLK32.05777751
17EIF2AK32.04739470
18TRIM281.91377997
19NME21.88950060
20PLK41.87126847
21MKNK21.83574809
22ATR1.80406877
23TAF11.80271694
24AURKB1.78291475
25SCYL21.63806907
26CDK71.63296613
27NUAK11.58838275
28PNCK1.58376675
29VRK11.56648380
30VRK21.56228341
31RPS6KB21.47468820
32CHEK21.47191125
33CHEK11.41682647
34TLK11.40817900
35RPS6KA41.36852218
36EPHA21.34142611
37MAP3K81.31920585
38DYRK31.27563897
39TESK21.25347426
40CDK41.22275289
41AURKA1.21887613
42STK161.14507267
43STK101.13747322
44TGFBR11.12435436
45CCNB11.12254386
46BRSK11.12051423
47ZAK1.06181316
48ATM1.05745980
49WNK31.04771258
50BRD41.01395699
51ALK1.00841843
52BCR1.00430010
53EEF2K0.99004846
54CDK20.95925575
55ERBB30.95388220
56PLK20.90734481
57BMPR1B0.88512165
58STK38L0.86915565
59TNIK0.86731474
60PIM10.86696364
61PAK40.85691238
62STK30.85373366
63STK40.81995290
64CSNK2A20.81258575
65CDK60.76689970
66FLT30.76524061
67CDK10.74866033
68EIF2AK20.70398902
69MELK0.69311279
70PDK30.65163094
71PDK40.65163094
72CSNK2A10.63824214
73ERBB40.63339735
74CSNK1G10.61646459
75BRAF0.60526428
76PAK10.59407472
77SIK30.57946518
78LATS20.57781539
79CSNK1E0.56576289
80MAP4K20.56091621
81PRKCI0.55886320
82MAP2K30.54517390
83RPS6KA50.53957651
84AKT30.52938330
85MST40.51363882
86CDK30.50206580
87NLK0.50155829
88NME10.49197329
89PBK0.48712017
90MAP3K100.47695693
91NEK60.47328491
92FGFR10.46991184
93LRRK20.46097545
94MTOR0.45326313
95PRKDC0.44272193
96TESK10.41634090
97PKN20.40568069
98MAP3K120.39960842
99CDK80.39738693
100AKT20.39167995
101CSNK1A1L0.37664596
102PIM20.36362222
103RPS6KB10.36045434
104LATS10.35413247
105MAP3K40.34994478
106CSNK1G20.34636420
107CSNK1D0.34480872
108PAK20.33418362
109DAPK10.33098243
110MAP3K90.32066123
111STK390.30221857
112MAPK140.29928921
113YES10.29540870
114MAPKAPK50.28329364
115MARK30.28257346
116PDK20.27983576
117STK240.26265968
118CDK90.25115950
119CSNK1G30.22666496
120KSR10.21503800
121MET0.20164029
122AKT10.20128371
123GSK3B0.20039788
124MAPK10.20035789
125NEK90.19737913
126PRKACB0.18806505
127CHUK0.18418474
128DYRK20.18336020
129CLK10.16793769
130MAPKAPK30.15785953

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.59946271
2* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.37973252
3Mismatch repair_Homo sapiens_hsa034304.13253923
4RNA transport_Homo sapiens_hsa030133.62293933
5RNA polymerase_Homo sapiens_hsa030203.56892640
6Spliceosome_Homo sapiens_hsa030403.46801119
7Ribosome_Homo sapiens_hsa030103.20070050
8Proteasome_Homo sapiens_hsa030503.05605977
9Homologous recombination_Homo sapiens_hsa034402.91140797
10Nucleotide excision repair_Homo sapiens_hsa034202.90502721
11One carbon pool by folate_Homo sapiens_hsa006702.90142583
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.89496986
13Cell cycle_Homo sapiens_hsa041102.88627107
14Base excision repair_Homo sapiens_hsa034102.70500220
15Non-homologous end-joining_Homo sapiens_hsa034502.33708344
16Pyrimidine metabolism_Homo sapiens_hsa002402.33697763
17Fanconi anemia pathway_Homo sapiens_hsa034602.17363254
18Basal transcription factors_Homo sapiens_hsa030222.15805703
19RNA degradation_Homo sapiens_hsa030182.13234350
20mRNA surveillance pathway_Homo sapiens_hsa030152.03348291
21Propanoate metabolism_Homo sapiens_hsa006401.87988437
22p53 signaling pathway_Homo sapiens_hsa041151.61870588
23Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.47956158
24Systemic lupus erythematosus_Homo sapiens_hsa053221.42846171
25Purine metabolism_Homo sapiens_hsa002301.31326196
26Pyruvate metabolism_Homo sapiens_hsa006201.30170493
27Epstein-Barr virus infection_Homo sapiens_hsa051691.29679005
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.25265756
29Steroid biosynthesis_Homo sapiens_hsa001001.22914360
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.15200860
31Oocyte meiosis_Homo sapiens_hsa041141.14967870
32Viral carcinogenesis_Homo sapiens_hsa052031.07803531
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.07358764
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.06500475
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.98188126
36Antigen processing and presentation_Homo sapiens_hsa046120.90717291
37Cysteine and methionine metabolism_Homo sapiens_hsa002700.87338246
38Herpes simplex infection_Homo sapiens_hsa051680.85049778
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83701449
40Biosynthesis of amino acids_Homo sapiens_hsa012300.80031115
41Cyanoamino acid metabolism_Homo sapiens_hsa004600.79311908
42Vitamin B6 metabolism_Homo sapiens_hsa007500.79027159
43Fatty acid elongation_Homo sapiens_hsa000620.76213098
44MicroRNAs in cancer_Homo sapiens_hsa052060.75745200
45Selenocompound metabolism_Homo sapiens_hsa004500.75450316
46HTLV-I infection_Homo sapiens_hsa051660.74741172
47Folate biosynthesis_Homo sapiens_hsa007900.70871345
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69311780
49Thyroid cancer_Homo sapiens_hsa052160.64105584
50Alcoholism_Homo sapiens_hsa050340.61340828
51Protein export_Homo sapiens_hsa030600.58869327
52Legionellosis_Homo sapiens_hsa051340.58572766
53TGF-beta signaling pathway_Homo sapiens_hsa043500.58499617
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56300994
55Fatty acid metabolism_Homo sapiens_hsa012120.56194112
56Small cell lung cancer_Homo sapiens_hsa052220.55134210
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.54460547
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52483560
59Lysine degradation_Homo sapiens_hsa003100.52232915
60Parkinsons disease_Homo sapiens_hsa050120.52167868
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50992971
62Pentose phosphate pathway_Homo sapiens_hsa000300.50931582
63Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50104394
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49288545
65Hippo signaling pathway_Homo sapiens_hsa043900.48834078
66Drug metabolism - other enzymes_Homo sapiens_hsa009830.44663323
67Basal cell carcinoma_Homo sapiens_hsa052170.41761003
68Oxidative phosphorylation_Homo sapiens_hsa001900.37205182
69Colorectal cancer_Homo sapiens_hsa052100.36052578
70Apoptosis_Homo sapiens_hsa042100.35825359
71N-Glycan biosynthesis_Homo sapiens_hsa005100.35442812
72Huntingtons disease_Homo sapiens_hsa050160.34540525
73Carbon metabolism_Homo sapiens_hsa012000.32841743
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32824314
75HIF-1 signaling pathway_Homo sapiens_hsa040660.31830848
76mTOR signaling pathway_Homo sapiens_hsa041500.30855860
77Regulation of autophagy_Homo sapiens_hsa041400.29270360
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.29009531
79Hedgehog signaling pathway_Homo sapiens_hsa043400.28467001
80Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.28232534
81Central carbon metabolism in cancer_Homo sapiens_hsa052300.27945508
82Fatty acid degradation_Homo sapiens_hsa000710.27074413
83Glutathione metabolism_Homo sapiens_hsa004800.26280502
84Hepatitis B_Homo sapiens_hsa051610.26186220
85Butanoate metabolism_Homo sapiens_hsa006500.26060357
86Bladder cancer_Homo sapiens_hsa052190.25207676
87Chronic myeloid leukemia_Homo sapiens_hsa052200.25167870
88Pathways in cancer_Homo sapiens_hsa052000.24969894
89Notch signaling pathway_Homo sapiens_hsa043300.23876881
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.23574900
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.22654866
92Arginine and proline metabolism_Homo sapiens_hsa003300.22594868
93Shigellosis_Homo sapiens_hsa051310.22121856
942-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.21595349
95Prostate cancer_Homo sapiens_hsa052150.20966582
96Sulfur metabolism_Homo sapiens_hsa009200.20800529
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.20501650
98Adherens junction_Homo sapiens_hsa045200.20122607
99Measles_Homo sapiens_hsa051620.19801221
100Viral myocarditis_Homo sapiens_hsa054160.19458503
101NF-kappa B signaling pathway_Homo sapiens_hsa040640.18344836
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.18156081
103Peroxisome_Homo sapiens_hsa041460.17582655
104Influenza A_Homo sapiens_hsa051640.17146496
105beta-Alanine metabolism_Homo sapiens_hsa004100.15881204
106PI3K-Akt signaling pathway_Homo sapiens_hsa041510.13181450
107Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.13167428
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.12714583
109Primary immunodeficiency_Homo sapiens_hsa053400.12529213
110Type I diabetes mellitus_Homo sapiens_hsa049400.12279809
111Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.12129838
112Renin-angiotensin system_Homo sapiens_hsa046140.12009775
113Fructose and mannose metabolism_Homo sapiens_hsa000510.11519342
114Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.10822050
115Melanoma_Homo sapiens_hsa052180.10459239
116Tight junction_Homo sapiens_hsa045300.10426143
117Proteoglycans in cancer_Homo sapiens_hsa052050.09344163
118Wnt signaling pathway_Homo sapiens_hsa043100.09188993
119Metabolic pathways_Homo sapiens_hsa011000.08700971
120Allograft rejection_Homo sapiens_hsa053300.07388616
121Sulfur relay system_Homo sapiens_hsa041220.07019884
122FoxO signaling pathway_Homo sapiens_hsa040680.06115798
123Alzheimers disease_Homo sapiens_hsa050100.05173418
124Vitamin digestion and absorption_Homo sapiens_hsa049770.02970388
125Tryptophan metabolism_Homo sapiens_hsa003800.02471931
126Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.02089266

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