WDR78

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium movement (GO:0003341)9.96534481
2motile cilium assembly (GO:0044458)9.38244196
3epithelial cilium movement (GO:0003351)8.92657005
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.80749699
5axoneme assembly (GO:0035082)7.25540851
6retinal cone cell development (GO:0046549)6.61139752
7sperm motility (GO:0030317)6.40873103
8regulation of rhodopsin mediated signaling pathway (GO:0022400)6.29925719
9ventricular system development (GO:0021591)6.10849598
10rhodopsin mediated signaling pathway (GO:0016056)6.06684499
11fusion of sperm to egg plasma membrane (GO:0007342)5.96466170
12acrosome assembly (GO:0001675)5.63135110
13intra-S DNA damage checkpoint (GO:0031573)5.55200052
14regulation of cilium movement (GO:0003352)5.32820805
15photoreceptor cell development (GO:0042461)5.29190349
16intraciliary transport (GO:0042073)5.19925766
17acrosome reaction (GO:0007340)5.15961081
18eye photoreceptor cell development (GO:0042462)5.14018778
19multicellular organism reproduction (GO:0032504)5.08993405
20imidazole-containing compound metabolic process (GO:0052803)4.98558616
21centriole assembly (GO:0098534)4.97189057
22sperm-egg recognition (GO:0035036)4.90006744
23spermatid development (GO:0007286)4.81507624
24photoreceptor cell maintenance (GO:0045494)4.76733105
25cilium organization (GO:0044782)4.73557982
26piRNA metabolic process (GO:0034587)4.73329199
27plasma membrane fusion (GO:0045026)4.66835838
28male meiosis (GO:0007140)4.54579309
29cilium assembly (GO:0042384)4.54373387
30cell wall macromolecule metabolic process (GO:0044036)4.50538458
31cell wall macromolecule catabolic process (GO:0016998)4.50538458
32left/right axis specification (GO:0070986)4.50191417
33peptidyl-lysine dimethylation (GO:0018027)4.46125014
34binding of sperm to zona pellucida (GO:0007339)4.42779976
35negative regulation of inclusion body assembly (GO:0090084)4.40014461
36retinal rod cell development (GO:0046548)4.36335020
37cell-cell recognition (GO:0009988)4.36213991
38protein localization to cilium (GO:0061512)4.36085523
39gamma-aminobutyric acid transport (GO:0015812)4.22171721
40GTP biosynthetic process (GO:0006183)4.07446950
41male meiosis I (GO:0007141)4.05127519
42determination of left/right symmetry (GO:0007368)4.03144743
43reproduction (GO:0000003)3.96922648
44detection of light stimulus involved in sensory perception (GO:0050962)3.92072659
45detection of light stimulus involved in visual perception (GO:0050908)3.92072659
46negative regulation of cytosolic calcium ion concentration (GO:0051481)3.87787477
47photoreceptor cell differentiation (GO:0046530)3.85631471
48eye photoreceptor cell differentiation (GO:0001754)3.85631471
49determination of bilateral symmetry (GO:0009855)3.84702691
50synaptonemal complex organization (GO:0070193)3.83935819
51cilium morphogenesis (GO:0060271)3.82600494
52nucleoside diphosphate phosphorylation (GO:0006165)3.80643912
53cellular component assembly involved in morphogenesis (GO:0010927)3.79048796
54single fertilization (GO:0007338)3.78368889
55specification of symmetry (GO:0009799)3.75264584
56microtubule-based movement (GO:0007018)3.71348068
57centriole replication (GO:0007099)3.69103429
58smoothened signaling pathway (GO:0007224)3.68320737
59microtubule severing (GO:0051013)3.67637362
60phototransduction (GO:0007602)3.59888481
61one-carbon compound transport (GO:0019755)3.57332150
62negative regulation of JUN kinase activity (GO:0043508)3.53235711
63microtubule bundle formation (GO:0001578)3.51559434
64UTP biosynthetic process (GO:0006228)3.50771082
65detection of light stimulus (GO:0009583)3.46916249
66phototransduction, visible light (GO:0007603)3.44160956
67visual perception (GO:0007601)3.40426192
68detection of visible light (GO:0009584)3.39530609
69V(D)J recombination (GO:0033151)3.36867482
70sensory perception of light stimulus (GO:0050953)3.36005152
71neural tube formation (GO:0001841)3.33911835
72microtubule depolymerization (GO:0007019)3.33401765
73synaptonemal complex assembly (GO:0007130)3.33375338
74regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.31997954
75regulation of inclusion body assembly (GO:0090083)3.31611029
76nonmotile primary cilium assembly (GO:0035058)3.30148454
77left/right pattern formation (GO:0060972)3.27220488
78spermatogenesis (GO:0007283)3.22616881
79retina development in camera-type eye (GO:0060041)3.21982855
80fertilization (GO:0009566)3.21170195
81male gamete generation (GO:0048232)3.20957255
82sperm capacitation (GO:0048240)3.20110550
83protein polyglutamylation (GO:0018095)3.16851289
84genitalia morphogenesis (GO:0035112)3.15824617
85guanosine-containing compound biosynthetic process (GO:1901070)3.15815422
86positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)3.15249440
87meiosis I (GO:0007127)3.14927601
88UTP metabolic process (GO:0046051)3.13583564
89calcium ion-dependent exocytosis (GO:0017156)3.12260287
90DNA methylation involved in gamete generation (GO:0043046)3.08672124
91regulation of microtubule-based movement (GO:0060632)3.08281500
92regulation of short-term neuronal synaptic plasticity (GO:0048172)3.06712145
93regulation of ARF protein signal transduction (GO:0032012)3.04511104
94methionine biosynthetic process (GO:0009086)3.04203708
95biotin metabolic process (GO:0006768)3.03791365
96organelle assembly (GO:0070925)3.03301507
97activated T cell proliferation (GO:0050798)3.03214860
98positive regulation of guanylate cyclase activity (GO:0031284)3.02100054
99vocalization behavior (GO:0071625)3.01927825
100GMP metabolic process (GO:0046037)2.99187706
101positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.98057959
102cell projection assembly (GO:0030031)2.97968501
103gamete generation (GO:0007276)2.96993155
104folic acid-containing compound biosynthetic process (GO:0009396)2.94232022
105phosphorelay signal transduction system (GO:0000160)2.93729338
106retina layer formation (GO:0010842)2.93150152
107protein-chromophore linkage (GO:0018298)2.90523896
108spermatid nucleus differentiation (GO:0007289)2.89578997
109regulation of centrosome duplication (GO:0010824)2.86615245
110regulation of cilium assembly (GO:1902017)2.85313274
111protein localization to synapse (GO:0035418)2.81733123
112cell recognition (GO:0008037)2.81046621
113protein refolding (GO:0042026)2.78477459
114CTP biosynthetic process (GO:0006241)2.75178092
115CTP metabolic process (GO:0046036)2.75178092
116negative regulation of thymocyte apoptotic process (GO:0070244)2.74666886
117positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.74019570
118germ cell development (GO:0007281)2.73384062
119cytoplasmic microtubule organization (GO:0031122)2.73321762
120methionine metabolic process (GO:0006555)2.72766609
121positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.70876813
122limb development (GO:0060173)2.70472743
123appendage development (GO:0048736)2.70472743
124microtubule-based process (GO:0007017)2.68571945
125regulation of guanylate cyclase activity (GO:0031282)2.67154354
126myoblast fusion (GO:0007520)2.66920990
127spinal cord motor neuron differentiation (GO:0021522)2.60358828
128microtubule polymerization or depolymerization (GO:0031109)2.59924888
129calcium ion import (GO:0070509)2.52929070
130neuron fate determination (GO:0048664)2.51104968
131short-chain fatty acid metabolic process (GO:0046459)2.50041980
132peptidyl-lysine trimethylation (GO:0018023)2.45372838
133establishment of nucleus localization (GO:0040023)2.42298130
134lateral ventricle development (GO:0021670)2.42288156
135regulation of autophagic vacuole assembly (GO:2000785)2.40129938
136diterpenoid biosynthetic process (GO:0016102)2.39955461
137asymmetric protein localization (GO:0008105)2.38970383
138inner ear receptor stereocilium organization (GO:0060122)2.38199665
139positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.35288766
140ethanol metabolic process (GO:0006067)2.35268360
141carnitine metabolic process (GO:0009437)2.33940240
142negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.33578786
143primary alcohol catabolic process (GO:0034310)2.32801525
144positive regulation of smoothened signaling pathway (GO:0045880)2.32486122
145gas transport (GO:0015669)2.32371209
146regulation of smoothened signaling pathway (GO:0008589)2.31388781
147membrane depolarization during action potential (GO:0086010)2.27616991
148regulation of vacuole organization (GO:0044088)2.24618802
149establishment of tissue polarity (GO:0007164)2.21665140
150establishment of planar polarity (GO:0001736)2.21665140
151brain morphogenesis (GO:0048854)2.20315605
152cell differentiation in spinal cord (GO:0021515)2.19963528
153microtubule-based transport (GO:0010970)2.18810939
154nucleus localization (GO:0051647)2.18757875
155vitamin transmembrane transport (GO:0035461)2.18747531
156regulation of insulin-like growth factor receptor signaling pathway (GO:0043567)2.17940097
157syncytium formation by plasma membrane fusion (GO:0000768)2.16890186
158reproductive system development (GO:0061458)2.14263333
159lateral sprouting from an epithelium (GO:0060601)2.10896556
160aspartate family amino acid biosynthetic process (GO:0009067)2.10599397
161icosanoid secretion (GO:0032309)2.06326285
162arachidonic acid secretion (GO:0050482)2.06326285
163regulation of centrosome cycle (GO:0046605)2.05295121
164histone H3-K9 demethylation (GO:0033169)2.05260087
165cilium or flagellum-dependent cell motility (GO:0001539)12.9701441
166axonemal dynein complex assembly (GO:0070286)10.8981663

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.90218545
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.13055940
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.54082587
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.38295210
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.31002256
6GBX2_23144817_ChIP-Seq_PC3_Human2.34589573
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.18826838
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.10030330
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.05069590
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.03209874
11ZNF274_21170338_ChIP-Seq_K562_Hela2.00370093
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.93751140
13REST_21632747_ChIP-Seq_MESCs_Mouse1.93192429
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.91079931
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.90542710
16PIAS1_25552417_ChIP-Seq_VCAP_Human1.90376937
17CBX2_27304074_Chip-Seq_ESCs_Mouse1.86328845
18ZFP57_27257070_Chip-Seq_ESCs_Mouse1.81741289
19TAF15_26573619_Chip-Seq_HEK293_Human1.77985564
20VDR_22108803_ChIP-Seq_LS180_Human1.77294600
21DROSHA_22980978_ChIP-Seq_HELA_Human1.77049577
22RNF2_27304074_Chip-Seq_NSC_Mouse1.75830455
23IGF1R_20145208_ChIP-Seq_DFB_Human1.73714309
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.70804675
25POU3F2_20337985_ChIP-ChIP_501MEL_Human1.70691357
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65641108
27SMAD4_21799915_ChIP-Seq_A2780_Human1.62035075
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.59259316
29SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58776043
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.56226563
31SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.55373094
32EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.53522561
33BCAT_22108803_ChIP-Seq_LS180_Human1.52357256
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.50055398
35EZH2_27294783_Chip-Seq_ESCs_Mouse1.49240925
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.46120669
37SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.44301575
38P300_19829295_ChIP-Seq_ESCs_Human1.43376737
39ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43209871
40TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.43119607
41FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.41968972
42TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39148997
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39148997
44AHR_22903824_ChIP-Seq_MCF-7_Human1.38997350
45RNF2_27304074_Chip-Seq_ESCs_Mouse1.38947599
46MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.38126881
47FUS_26573619_Chip-Seq_HEK293_Human1.37894744
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37439099
49LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37311327
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36990965
51JARID2_20064375_ChIP-Seq_MESCs_Mouse1.35551898
52FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.34945836
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.34669048
54MTF2_20144788_ChIP-Seq_MESCs_Mouse1.34590934
55TCF4_22108803_ChIP-Seq_LS180_Human1.34430598
56ER_23166858_ChIP-Seq_MCF-7_Human1.34259932
57TP53_16413492_ChIP-PET_HCT116_Human1.34242352
58RUNX2_22187159_ChIP-Seq_PCA_Human1.33721808
59ELK4_26923725_Chip-Seq_MESODERM_Mouse1.33462729
60TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.33058141
61GATA1_26923725_Chip-Seq_HPCs_Mouse1.32612206
62SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.31334925
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.29925505
64WDR5_24793694_ChIP-Seq_LNCAP_Human1.29169482
65EZH2_27304074_Chip-Seq_ESCs_Mouse1.28871935
66TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.28739805
67FLI1_27457419_Chip-Seq_LIVER_Mouse1.27722485
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.27407393
69* STAT3_23295773_ChIP-Seq_U87_Human1.27161102
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27127464
71SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.26687106
72TCF4_23295773_ChIP-Seq_U87_Human1.26484009
73RNF2_18974828_ChIP-Seq_MESCs_Mouse1.26264530
74EZH2_18974828_ChIP-Seq_MESCs_Mouse1.26264530
75MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25589348
76* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.24709487
77FOXM1_26456572_ChIP-Seq_MCF-7_Human1.24640460
78CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24220124
79NANOG_18555785_Chip-Seq_ESCs_Mouse1.23536683
80RARB_27405468_Chip-Seq_BRAIN_Mouse1.23490202
81CTNNB1_20460455_ChIP-Seq_HCT116_Human1.22637790
82CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.22174608
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21644118
84SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.20572557
85IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20170520
86CBP_20019798_ChIP-Seq_JUKART_Human1.20170520
87ESR1_20079471_ChIP-ChIP_T-47D_Human1.19516873
88FLI1_21867929_ChIP-Seq_TH2_Mouse1.18860833
89REST_18959480_ChIP-ChIP_MESCs_Mouse1.18661066
90* SOX2_21211035_ChIP-Seq_LN229_Gbm1.18074991
91PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18026912
92JARID2_20075857_ChIP-Seq_MESCs_Mouse1.17565104
93TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17231816
94TAL1_26923725_Chip-Seq_HPCs_Mouse1.16329982
95KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15465737
96EGR1_23403033_ChIP-Seq_LIVER_Mouse1.13586366
97AR_25329375_ChIP-Seq_VCAP_Human1.13514343
98RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.12593991
99UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12000739
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.11645313
101AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11440875
102SUZ12_27294783_Chip-Seq_NPCs_Mouse1.10766923
103P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09840419
104ARNT_22903824_ChIP-Seq_MCF-7_Human1.09306233
105* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07886947
106EWS_26573619_Chip-Seq_HEK293_Human1.07616062
107KDM2B_26808549_Chip-Seq_REH_Human1.07432882
108SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.07192298
109KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06462575
110TP53_18474530_ChIP-ChIP_U2OS_Human1.06140502
111E2F1_18555785_Chip-Seq_ESCs_Mouse1.06063930
112* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05683150
113* TBL1_22424771_ChIP-Seq_293T_Human1.05627242
114NFE2_27457419_Chip-Seq_LIVER_Mouse1.05068499
115EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04695831
116SALL1_21062744_ChIP-ChIP_HESCs_Human1.04364924
117TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03674696
118AR_21572438_ChIP-Seq_LNCaP_Human1.03226056
119SMAD4_21741376_ChIP-Seq_EPCs_Human1.03167794
120CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03006142
121NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02740257
122* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02429181
123RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01961240
124AR_19668381_ChIP-Seq_PC3_Human1.01941553
125* PHF8_20622853_ChIP-Seq_HELA_Human1.00678797
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.99824105
127P53_22387025_ChIP-Seq_ESCs_Mouse0.99730703
128TP53_22573176_ChIP-Seq_HFKS_Human0.99107120
129FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98971208
130PRDM14_20953172_ChIP-Seq_ESCs_Human0.96754454
131SMRT_27268052_Chip-Seq_Bcells_Human0.96403216
132* ETV1_20927104_ChIP-Seq_GIST48_Human0.96345146
133* NFYB_21822215_ChIP-Seq_K562_Human0.94633412
134STAT3_18555785_Chip-Seq_ESCs_Mouse0.93852625
135NR3C1_23031785_ChIP-Seq_PC12_Mouse0.93307910
136* CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.91750484

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.50553836
2MP0005551_abnormal_eye_electrophysiolog5.36017785
3MP0003011_delayed_dark_adaptation4.70088225
4MP0005253_abnormal_eye_physiology3.71066029
5MP0006072_abnormal_retinal_apoptosis3.40722735
6MP0001485_abnormal_pinna_reflex3.30607090
7MP0002653_abnormal_ependyma_morphology3.19716090
8MP0003698_abnormal_male_reproductive2.80162177
9MP0000383_abnormal_hair_follicle2.78674369
10MP0008877_abnormal_DNA_methylation2.64347720
11MP0005423_abnormal_somatic_nervous2.37519985
12MP0001929_abnormal_gametogenesis2.34346458
13MP0008875_abnormal_xenobiotic_pharmacok2.33680208
14MP0004859_abnormal_synaptic_plasticity2.32301579
15MP0002638_abnormal_pupillary_reflex2.28887291
16MP0001984_abnormal_olfaction2.26521616
17MP0005195_abnormal_posterior_eye2.23923689
18MP0003880_abnormal_central_pattern2.15475087
19MP0004043_abnormal_pH_regulation2.09130220
20MP0005391_vision/eye_phenotype2.08462946
21MP0002160_abnormal_reproductive_system2.07618785
22MP0009046_muscle_twitch2.05400676
23MP0003635_abnormal_synaptic_transmissio1.96864489
24MP0005409_darkened_coat_color1.96291490
25MP0010678_abnormal_skin_adnexa1.90736568
26MP0001324_abnormal_eye_pigmentation1.86684703
27MP0000569_abnormal_digit_pigmentation1.81745247
28MP0009745_abnormal_behavioral_response1.79565940
29MP0003787_abnormal_imprinting1.67632909
30MP0002063_abnormal_learning/memory/cond1.65155789
31MP0002210_abnormal_sex_determination1.63793660
32MP0002064_seizures1.61246982
33MP0003890_abnormal_embryonic-extraembry1.60424065
34MP0004270_analgesia1.59234624
35MP0003878_abnormal_ear_physiology1.56858810
36MP0005377_hearing/vestibular/ear_phenot1.56858810
37MP0001486_abnormal_startle_reflex1.55111094
38MP0002572_abnormal_emotion/affect_behav1.54805936
39MP0005171_absent_coat_pigmentation1.54503669
40MP0001440_abnormal_grooming_behavior1.53529913
41MP0001986_abnormal_taste_sensitivity1.52363232
42MP0005646_abnormal_pituitary_gland1.48919572
43MP0002229_neurodegeneration1.48439648
44MP0008004_abnormal_stomach_pH1.45684791
45MP0005623_abnormal_meninges_morphology1.45574517
46MP0002161_abnormal_fertility/fecundity1.45554445
47MP0003950_abnormal_plasma_membrane1.41252494
48MP0002752_abnormal_somatic_nervous1.41043105
49MP0001502_abnormal_circadian_rhythm1.39633302
50MP0001501_abnormal_sleep_pattern1.39585051
51MP0003122_maternal_imprinting1.38908000
52MP0002882_abnormal_neuron_morphology1.35881344
53MP0000778_abnormal_nervous_system1.34173211
54MP0002272_abnormal_nervous_system1.33726083
55MP0002557_abnormal_social/conspecific_i1.29775430
56MP0001145_abnormal_male_reproductive1.27702247
57MP0002876_abnormal_thyroid_physiology1.26348026
58MP0010386_abnormal_urinary_bladder1.24913841
59MP0002132_abnormal_respiratory_system1.23948283
60MP0004142_abnormal_muscle_tone1.23703084
61MP0001968_abnormal_touch/_nociception1.23658655
62MP0003937_abnormal_limbs/digits/tail_de1.23626153
63MP0002734_abnormal_mechanical_nocicepti1.22329703
64MP0000566_synostosis1.21072441
65MP0004233_abnormal_muscle_weight1.19492003
66MP0000427_abnormal_hair_cycle1.17399424
67MP0000653_abnormal_sex_gland1.14752116
68MP0002067_abnormal_sensory_capabilities1.13454132
69MP0002909_abnormal_adrenal_gland1.12312864
70MP0000049_abnormal_middle_ear1.11351148
71MP0002090_abnormal_vision1.10262266
72MP0002249_abnormal_larynx_morphology1.06523066
73MP0003121_genomic_imprinting1.06452612
74MP0001293_anophthalmia1.05355113
75MP0001177_atelectasis1.04384158
76MP0008569_lethality_at_weaning1.04383370
77MP0004742_abnormal_vestibular_system1.01691570
78MP0004811_abnormal_neuron_physiology0.98032429
79MP0005389_reproductive_system_phenotype0.97942688
80MP0003283_abnormal_digestive_organ0.94886579
81MP0002277_abnormal_respiratory_mucosa0.93471869
82MP0002233_abnormal_nose_morphology0.93166301
83MP0002822_catalepsy0.93064717
84MP0002152_abnormal_brain_morphology0.92670848
85MP0000631_abnormal_neuroendocrine_gland0.91559708
86MP0002184_abnormal_innervation0.91449615
87MP0005499_abnormal_olfactory_system0.91040111
88MP0005394_taste/olfaction_phenotype0.91040111
89MP0006276_abnormal_autonomic_nervous0.90135426
90MP0004885_abnormal_endolymph0.89882078
91MP0002234_abnormal_pharynx_morphology0.88544570
92MP0002282_abnormal_trachea_morphology0.85561747
93MP0002332_abnormal_exercise_endurance0.83465288
94MP0005647_abnormal_sex_gland0.83049101
95MP0003633_abnormal_nervous_system0.83012722
96MP0004019_abnormal_vitamin_homeostasis0.82578072
97MP0004808_abnormal_hematopoietic_stem0.82530323
98MP0008057_abnormal_DNA_replication0.82415258
99MP0003195_calcinosis0.80986617
100MP0001756_abnormal_urination0.80305564
101MP0001849_ear_inflammation0.80171659
102MP0003136_yellow_coat_color0.79547540
103MP0001905_abnormal_dopamine_level0.79391787
104MP0005386_behavior/neurological_phenoty0.79237451
105MP0004924_abnormal_behavior0.79237451
106MP0001963_abnormal_hearing_physiology0.79181895
107MP0008995_early_reproductive_senescence0.77799256
108MP0002928_abnormal_bile_duct0.77766150
109MP0003879_abnormal_hair_cell0.77654116
110MP0002735_abnormal_chemical_nociception0.76349346
111MP0004215_abnormal_myocardial_fiber0.76318501
112MP0006292_abnormal_olfactory_placode0.76012785
113MP0002736_abnormal_nociception_after0.75388878
114MP0005645_abnormal_hypothalamus_physiol0.74580731
115MP0003861_abnormal_nervous_system0.74158713
116MP0002733_abnormal_thermal_nociception0.73834290
117MP0003634_abnormal_glial_cell0.72817906
118MP0002102_abnormal_ear_morphology0.71286724
119MP0001545_abnormal_hematopoietic_system0.70600323
120MP0005397_hematopoietic_system_phenotyp0.70600323
121MP0000647_abnormal_sebaceous_gland0.69332061
122MP0005167_abnormal_blood-brain_barrier0.68364076
123MP0002116_abnormal_craniofacial_bone0.67765917
124MP0000955_abnormal_spinal_cord0.67089186
125MP0003252_abnormal_bile_duct0.66692649
126MP0010030_abnormal_orbit_morphology0.66663841
127MP0000026_abnormal_inner_ear0.65297353
128MP0008789_abnormal_olfactory_epithelium0.64884453
129MP0001970_abnormal_pain_threshold0.64794503
130MP0004133_heterotaxia0.64701345
131MP0002066_abnormal_motor_capabilities/c0.62055266
132MP0001879_abnormal_lymphatic_vessel0.60945415
133MP0001919_abnormal_reproductive_system0.60345454
134MP0008961_abnormal_basal_metabolism0.59243301
135MP0009780_abnormal_chondrocyte_physiolo0.57832743

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.59928742
2Abnormal respiratory motile cilium physiology (HP:0012261)8.99858036
3Absent/shortened dynein arms (HP:0200106)8.71404943
4Dynein arm defect of respiratory motile cilia (HP:0012255)8.71404943
5Abnormal ciliary motility (HP:0012262)8.71094017
6Abnormal respiratory epithelium morphology (HP:0012253)7.71700643
7Abnormal respiratory motile cilium morphology (HP:0005938)7.71700643
8Rhinitis (HP:0012384)7.22137333
9Congenital stationary night blindness (HP:0007642)5.96018728
10Bony spicule pigmentary retinopathy (HP:0007737)5.64183145
11Chronic bronchitis (HP:0004469)5.19475625
12Bronchiectasis (HP:0002110)4.70353251
13Abnormal rod and cone electroretinograms (HP:0008323)4.11788308
14Absent rod-and cone-mediated responses on ERG (HP:0007688)3.96018858
15Nasal polyposis (HP:0100582)3.94949743
16Bile duct proliferation (HP:0001408)3.78194155
17Abnormal biliary tract physiology (HP:0012439)3.78194155
18Nephronophthisis (HP:0000090)3.74137681
19Infertility (HP:0000789)3.67997652
20Abnormality of macular pigmentation (HP:0008002)3.67255366
21Medial flaring of the eyebrow (HP:0010747)3.51379536
22Decreased central vision (HP:0007663)3.46569346
23Central scotoma (HP:0000603)3.37327860
24Dyschromatopsia (HP:0007641)3.30702091
25Pancreatic fibrosis (HP:0100732)3.29906513
26True hermaphroditism (HP:0010459)3.29721133
27Attenuation of retinal blood vessels (HP:0007843)3.29042874
28Congenital primary aphakia (HP:0007707)3.26473060
29Gait imbalance (HP:0002141)3.26158333
30Pigmentary retinal degeneration (HP:0001146)3.19372234
31Abnormality of the nasal mucosa (HP:0000433)3.18672024
32Polydipsia (HP:0001959)3.17953625
33Abnormal drinking behavior (HP:0030082)3.17953625
34Chronic sinusitis (HP:0011109)3.11298418
35Chorioretinal atrophy (HP:0000533)3.05764004
36Abnormality of midbrain morphology (HP:0002418)3.04041048
37Molar tooth sign on MRI (HP:0002419)3.04041048
38Recurrent sinusitis (HP:0011108)3.01386224
39Abnormality of the renal medulla (HP:0100957)3.00179887
40Abnormality of the renal cortex (HP:0011035)2.96546668
41Scotoma (HP:0000575)2.93471509
42Bell-shaped thorax (HP:0001591)2.89256571
43Bronchitis (HP:0012387)2.88131533
44Tubulointerstitial nephritis (HP:0001970)2.85879782
45Nephrogenic diabetes insipidus (HP:0009806)2.83806894
46Pendular nystagmus (HP:0012043)2.69875652
47Type II diabetes mellitus (HP:0005978)2.68688877
48Retinitis pigmentosa (HP:0000510)2.61590607
49Recurrent otitis media (HP:0000403)2.52427078
50Abolished electroretinogram (ERG) (HP:0000550)2.50621365
51Photophobia (HP:0000613)2.48432915
52Genital tract atresia (HP:0001827)2.41722408
53Constricted visual fields (HP:0001133)2.41265563
54Pancreatic cysts (HP:0001737)2.39319954
55Vaginal atresia (HP:0000148)2.37586245
56Cystic liver disease (HP:0006706)2.35940036
57Cone-rod dystrophy (HP:0000548)2.35545043
58Postaxial foot polydactyly (HP:0001830)2.33106753
59Furrowed tongue (HP:0000221)2.32572820
60Poor coordination (HP:0002370)2.31394363
61Aplasia/Hypoplasia of the tongue (HP:0010295)2.28901864
62Median cleft lip (HP:0000161)2.28852106
63Fibular hypoplasia (HP:0003038)2.28088430
64Recurrent bronchitis (HP:0002837)2.24753706
65Occipital encephalocele (HP:0002085)2.21209320
66Choroideremia (HP:0001139)2.17700134
67Congenital hepatic fibrosis (HP:0002612)2.17097112
68Aplasia/Hypoplasia of the lens (HP:0008063)2.15633377
69Male pseudohermaphroditism (HP:0000037)2.14869354
70Macular degeneration (HP:0000608)2.12933468
71Severe visual impairment (HP:0001141)2.12163222
72Polyuria (HP:0000103)2.11573344
73Postaxial hand polydactyly (HP:0001162)2.06286110
74Intellectual disability, moderate (HP:0002342)2.05753473
75Supernumerary spleens (HP:0009799)2.04150302
76Anophthalmia (HP:0000528)2.00235665
77Abnormality of B cell number (HP:0010975)1.99702053
78B lymphocytopenia (HP:0010976)1.99702053
79Chronic hepatic failure (HP:0100626)1.91627993
80Optic nerve coloboma (HP:0000588)1.86037004
81Abnormal urine output (HP:0012590)1.83796759
82Narrow forehead (HP:0000341)1.80383897
83Sclerocornea (HP:0000647)1.77676893
84Keratoconus (HP:0000563)1.77303885
85Increased corneal curvature (HP:0100692)1.77303885
86Focal motor seizures (HP:0011153)1.74914223
87Chronic otitis media (HP:0000389)1.72560639
88Abnormality of renal excretion (HP:0011036)1.72399982
89Abnormality of the dental root (HP:0006486)1.71504794
90Taurodontia (HP:0000679)1.71504794
91Abnormality of permanent molar morphology (HP:0011071)1.71504794
92Tubulointerstitial abnormality (HP:0001969)1.71071493
93Specific learning disability (HP:0001328)1.69228355
94Genetic anticipation (HP:0003743)1.67265078
95Facial cleft (HP:0002006)1.61121228
96Febrile seizures (HP:0002373)1.60901914
97Abnormality of molar (HP:0011077)1.60707728
98Abnormality of molar morphology (HP:0011070)1.60707728
99Preaxial hand polydactyly (HP:0001177)1.60017035
100Progressive cerebellar ataxia (HP:0002073)1.59962161
101Abnormality of the lower motor neuron (HP:0002366)1.59450369
102Stage 5 chronic kidney disease (HP:0003774)1.58999896
103Oculomotor apraxia (HP:0000657)1.58910437
104Hypoplasia of the thymus (HP:0000778)1.58560543
105Portal hypertension (HP:0001409)1.57227710
106Anencephaly (HP:0002323)1.57002887
107Atelectasis (HP:0100750)1.57001296
108Prominent nasal bridge (HP:0000426)1.55522376
109T lymphocytopenia (HP:0005403)1.53518376
110Abnormality of dentin (HP:0010299)1.53173664
111Thyroiditis (HP:0100646)1.52490596
112Nephropathy (HP:0000112)1.52056486
113Epileptic encephalopathy (HP:0200134)1.50832229
114Abnormality of the dental pulp (HP:0006479)1.49919116
115Bifid tongue (HP:0010297)1.49814528
116Highly arched eyebrow (HP:0002553)1.49601161
117Amyotrophic lateral sclerosis (HP:0007354)1.48690226
118Hyperglycinemia (HP:0002154)1.45930781
119Abnormality of the hepatic vasculature (HP:0006707)1.44436830
120Gaze-evoked nystagmus (HP:0000640)1.44089579
121Aganglionic megacolon (HP:0002251)1.43744480
122Male infertility (HP:0003251)1.43159628
123Broad foot (HP:0001769)1.42714757
124Abnormality of T cell number (HP:0011839)1.41806780
125Tubular atrophy (HP:0000092)1.40700955
126Aplasia/Hypoplasia of the fibula (HP:0006492)1.39246610
127Dental crowding (HP:0000678)1.37462973
128Type II lissencephaly (HP:0007260)1.29462129
129Hyperactive renin-angiotensin system (HP:0000841)1.24333583
130Hyperglycinuria (HP:0003108)1.21206705
131Chorioretinal coloboma (HP:0000567)1.20663333
132Multicystic kidney dysplasia (HP:0000003)1.19539354
133Abnormal number of erythroid precursors (HP:0012131)1.17714982
134Autoimmune hemolytic anemia (HP:0001890)1.15803067
135Renal dysplasia (HP:0000110)1.14154576
136Decreased circulating renin level (HP:0003351)1.13519022
137Long face (HP:0000276)1.12865715
138Poor eye contact (HP:0000817)1.12122950
139Metaphyseal dysplasia (HP:0100255)1.08924060
140Hyperventilation (HP:0002883)1.08118705
141Oligohydramnios (HP:0001562)1.06927887
142Abnormality of the fingertips (HP:0001211)1.06352667
143Iris coloboma (HP:0000612)1.05181760
144Hypoplastic labia majora (HP:0000059)1.04979715
145Asthma (HP:0002099)1.03829269
146Dandy-Walker malformation (HP:0001305)1.03752700

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK5.09278677
2PDK34.58524759
3PDK44.58524759
4FRK3.60672632
5GRK13.56747241
6MAP4K22.73216233
7TLK12.69604125
8PDK22.64534684
9NTRK22.51020337
10MST42.27716079
11MAPK152.26298157
12MET2.24077913
13WNK32.20246107
14PRKD32.11930523
15ICK2.07188619
16SIK31.99640421
17NTRK31.83058237
18STK391.78294626
19CAMK1G1.73921124
20ZAK1.73666804
21MAP3K41.70585343
22SIK21.69252950
23TNIK1.63872451
24PTK2B1.63184370
25TXK1.56493791
26YES11.48143979
27ADRBK21.45563058
28WNK41.45403873
29MINK11.41301924
30CASK1.40705783
31MUSK1.40336527
32TESK11.40297650
33EPHA41.38436557
34CDK31.37146080
35PLK21.34973758
36STK38L1.26655998
37WNK11.23492799
38MARK11.21218272
39NEK21.19444819
40STK31.19069457
41IRAK21.18783760
42CAMKK11.17484419
43STK381.07449044
44IRAK11.03987076
45FGR1.02073024
46FGFR21.00517934
47PBK0.98500029
48CAMK40.97957725
49MAP2K70.95175993
50RPS6KA50.94909731
51BMX0.94213884
52CAMKK20.91810024
53LATS10.91511264
54PDGFRB0.89192703
55PRKCG0.88671694
56ERBB30.87117552
57TAOK30.86993715
58CSNK1G20.86334106
59DAPK20.84734108
60MKNK20.84242894
61ACVR1B0.83568890
62CSF1R0.81676559
63SGK20.80318067
64BCR0.80062069
65MAPK70.79760322
66MARK20.79534157
67LMTK20.78717958
68OXSR10.78442512
69EPHA20.78413261
70MAPK130.77508658
71CCNB10.76541851
72NEK60.76348385
73DYRK1B0.75169903
74PRKCH0.74004436
75VRK10.73220649
76NUAK10.72837977
77DYRK1A0.72693462
78ZAP700.71639755
79CAMK10.70858675
80PLK40.69897146
81AKT30.68939068
82CSNK1A1L0.68773615
83CDK50.68591025
84MAP3K120.66393967
85STK160.66293689
86RET0.64205773
87CDC70.64032757
88PHKG10.63203113
89PHKG20.63203113
90MAP3K20.62812486
91PINK10.61434917
92TRPM70.60924429
93PRKCI0.60442750
94PRKCE0.59679434
95EPHA30.59154136
96BMPR1B0.58776259
97ERBB20.58396196
98GRK50.56467506
99MAPKAPK30.56369477
100PRKAA10.55545033
101KSR10.55294552
102TNK20.55151231
103CSNK1G10.54444294
104BLK0.54377059
105CAMK2A0.54104505
106FER0.53984212
107ADRBK10.53219139
108BRSK20.53173868
109PRKCQ0.51728233
110MAP2K40.51562909
111MAP3K70.51245749
112FYN0.50776204
113FES0.49869689
114MAP3K90.49008133
115PAK60.48941885
116CSNK1G30.46059809
117PAK30.45158725
118DYRK30.44625084
119UHMK10.44377199
120MAPK100.43516368
121RPS6KA30.43411805
122SGK10.43026401
123PDK10.42746439
124CSNK1D0.42523704
125ROCK10.41478586
126MAP2K60.40882977
127HIPK20.39870594
128TYRO30.39803789
129PRKCB0.38753563
130CAMK2B0.38457611
131GSK3B0.38372930
132CHEK20.37694869
133PRKACA0.36702335
134PRKG10.36566748
135GRK70.36551916
136PRKD20.36538571
137STK110.36283531
138CSNK1E0.36085807
139INSRR0.35816904
140SGK4940.34997446
141SGK2230.34997446
142WEE10.34441334
143PRKCZ0.34009745
144NLK0.30452096
145PRKCA0.30089109
146PKN10.29644537
147TIE10.28247754

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047449.40925069
2Systemic lupus erythematosus_Homo sapiens_hsa053223.23725113
3Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.77457503
4Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.69098572
5Olfactory transduction_Homo sapiens_hsa047402.64240200
6Nicotine addiction_Homo sapiens_hsa050332.59299331
7Chemical carcinogenesis_Homo sapiens_hsa052042.42798247
8One carbon pool by folate_Homo sapiens_hsa006702.42204196
9Propanoate metabolism_Homo sapiens_hsa006402.17351066
10Histidine metabolism_Homo sapiens_hsa003402.15172762
11Synaptic vesicle cycle_Homo sapiens_hsa047212.07836937
12Amphetamine addiction_Homo sapiens_hsa050311.90066752
13GABAergic synapse_Homo sapiens_hsa047271.85327976
14Primary bile acid biosynthesis_Homo sapiens_hsa001201.83867681
15Circadian entrainment_Homo sapiens_hsa047131.82092485
16Linoleic acid metabolism_Homo sapiens_hsa005911.77602327
17Oxidative phosphorylation_Homo sapiens_hsa001901.74915490
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.73262902
19Long-term potentiation_Homo sapiens_hsa047201.70445080
20Morphine addiction_Homo sapiens_hsa050321.68867205
21Glutamatergic synapse_Homo sapiens_hsa047241.66261162
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.63862104
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.60948814
24Dopaminergic synapse_Homo sapiens_hsa047281.60684837
25Renin secretion_Homo sapiens_hsa049241.60469892
26Caffeine metabolism_Homo sapiens_hsa002321.57707030
27beta-Alanine metabolism_Homo sapiens_hsa004101.56895724
28Peroxisome_Homo sapiens_hsa041461.53861070
29Circadian rhythm_Homo sapiens_hsa047101.50861616
30Gastric acid secretion_Homo sapiens_hsa049711.46663587
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.45158909
32Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.43077428
33Nitrogen metabolism_Homo sapiens_hsa009101.39252577
34Primary immunodeficiency_Homo sapiens_hsa053401.38881519
35Salivary secretion_Homo sapiens_hsa049701.37675660
36Retinol metabolism_Homo sapiens_hsa008301.36834322
37Tyrosine metabolism_Homo sapiens_hsa003501.34429120
38Insulin secretion_Homo sapiens_hsa049111.32900489
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.30640903
40Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.27865110
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.27325410
42Calcium signaling pathway_Homo sapiens_hsa040201.26248441
43Phenylalanine metabolism_Homo sapiens_hsa003601.25979310
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.24545284
45Dorso-ventral axis formation_Homo sapiens_hsa043201.24531787
46Taste transduction_Homo sapiens_hsa047421.24443058
47Steroid hormone biosynthesis_Homo sapiens_hsa001401.23195667
48Butanoate metabolism_Homo sapiens_hsa006501.22666372
49Cholinergic synapse_Homo sapiens_hsa047251.20496336
50Cocaine addiction_Homo sapiens_hsa050301.19388605
51Glucagon signaling pathway_Homo sapiens_hsa049221.19066261
52Serotonergic synapse_Homo sapiens_hsa047261.18076327
53Tryptophan metabolism_Homo sapiens_hsa003801.14487901
54Selenocompound metabolism_Homo sapiens_hsa004501.12597921
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.10748156
56Glutathione metabolism_Homo sapiens_hsa004801.08103610
57Oxytocin signaling pathway_Homo sapiens_hsa049211.07491476
58Alzheimers disease_Homo sapiens_hsa050101.07460943
59Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06291602
60Parkinsons disease_Homo sapiens_hsa050121.05171951
61alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.02664766
62cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01742622
63T cell receptor signaling pathway_Homo sapiens_hsa046601.00622838
64Oocyte meiosis_Homo sapiens_hsa041141.00280180
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.99223420
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.98980527
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.98848138
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98726397
69cAMP signaling pathway_Homo sapiens_hsa040240.98670151
70Wnt signaling pathway_Homo sapiens_hsa043100.97915068
71Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.97111409
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94892423
73Regulation of autophagy_Homo sapiens_hsa041400.94450598
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.94114531
75Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.91503931
76Vitamin B6 metabolism_Homo sapiens_hsa007500.90618392
77Huntingtons disease_Homo sapiens_hsa050160.88573339
78Axon guidance_Homo sapiens_hsa043600.85935157
79Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.82975500
80Basal cell carcinoma_Homo sapiens_hsa052170.82463478
81Estrogen signaling pathway_Homo sapiens_hsa049150.80017650
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79849475
83Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.79092213
84Cardiac muscle contraction_Homo sapiens_hsa042600.77415115
85Melanogenesis_Homo sapiens_hsa049160.76039297
86Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.74110716
87Collecting duct acid secretion_Homo sapiens_hsa049660.73966747
88Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73704755
89mRNA surveillance pathway_Homo sapiens_hsa030150.71067592
90Fatty acid degradation_Homo sapiens_hsa000710.69632714
91Inositol phosphate metabolism_Homo sapiens_hsa005620.68569483
92Thyroid hormone synthesis_Homo sapiens_hsa049180.68129680
93Non-homologous end-joining_Homo sapiens_hsa034500.67847564
94Arachidonic acid metabolism_Homo sapiens_hsa005900.67792842
95Mineral absorption_Homo sapiens_hsa049780.66780564
96Ether lipid metabolism_Homo sapiens_hsa005650.65669793
97Alcoholism_Homo sapiens_hsa050340.64548116
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63898437
99Basal transcription factors_Homo sapiens_hsa030220.62719464
100Hedgehog signaling pathway_Homo sapiens_hsa043400.61854554
101Bile secretion_Homo sapiens_hsa049760.61592409
102Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61054129
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59989333
104Sphingolipid metabolism_Homo sapiens_hsa006000.59480755
105Viral carcinogenesis_Homo sapiens_hsa052030.59384058
106GnRH signaling pathway_Homo sapiens_hsa049120.58719487
107Pyruvate metabolism_Homo sapiens_hsa006200.57173192
108Metabolic pathways_Homo sapiens_hsa011000.56636683
109Glycerolipid metabolism_Homo sapiens_hsa005610.56427943
110Gap junction_Homo sapiens_hsa045400.54728846
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53787120
112Purine metabolism_Homo sapiens_hsa002300.52832931
113MAPK signaling pathway_Homo sapiens_hsa040100.52823357
114Pancreatic secretion_Homo sapiens_hsa049720.52759270
115ErbB signaling pathway_Homo sapiens_hsa040120.52408839
116Vascular smooth muscle contraction_Homo sapiens_hsa042700.51779351
117Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51662796
118Hippo signaling pathway_Homo sapiens_hsa043900.51282948
119Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.51076466
120Long-term depression_Homo sapiens_hsa047300.51073570
121Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50196673
122Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47578612
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46324699
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46048530
125Ovarian steroidogenesis_Homo sapiens_hsa049130.45045604
126Tight junction_Homo sapiens_hsa045300.43983300
127Fatty acid biosynthesis_Homo sapiens_hsa000610.43007073
128Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42746469
129Antigen processing and presentation_Homo sapiens_hsa046120.41865941
130Glycerophospholipid metabolism_Homo sapiens_hsa005640.39705195
131Phospholipase D signaling pathway_Homo sapiens_hsa040720.39464941
132N-Glycan biosynthesis_Homo sapiens_hsa005100.37837485
133Type II diabetes mellitus_Homo sapiens_hsa049300.37494976
134SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35907614
135Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35355465
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35098761
137Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34703535
138Choline metabolism in cancer_Homo sapiens_hsa052310.33907818
139Endocytosis_Homo sapiens_hsa041440.33723004
140Arginine and proline metabolism_Homo sapiens_hsa003300.33510821
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.33257499
142Fanconi anemia pathway_Homo sapiens_hsa034600.31160319
143ABC transporters_Homo sapiens_hsa020100.30155483
144AMPK signaling pathway_Homo sapiens_hsa041520.29928348
145Endometrial cancer_Homo sapiens_hsa052130.29744361
146mTOR signaling pathway_Homo sapiens_hsa041500.29016536
147Ras signaling pathway_Homo sapiens_hsa040140.28729996
148Colorectal cancer_Homo sapiens_hsa052100.27817707
149Dilated cardiomyopathy_Homo sapiens_hsa054140.27114599
150Notch signaling pathway_Homo sapiens_hsa043300.26717802
151Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.25760766
152Glioma_Homo sapiens_hsa052140.25352532

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