WDR93

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)9.22321796
2axonemal dynein complex assembly (GO:0070286)9.20193495
3regulation of cilium movement (GO:0003352)8.87453895
4sperm motility (GO:0030317)8.10009572
5acrosome assembly (GO:0001675)7.93496556
6multicellular organism reproduction (GO:0032504)7.64099284
7cilium movement (GO:0003341)7.52120139
8motile cilium assembly (GO:0044458)7.43582138
9sperm-egg recognition (GO:0035036)7.38547718
10epithelial cilium movement (GO:0003351)7.25021731
11ventricular system development (GO:0021591)7.02567817
12piRNA metabolic process (GO:0034587)7.00455021
13plasma membrane fusion (GO:0045026)6.81914587
14binding of sperm to zona pellucida (GO:0007339)6.74566301
15cell wall macromolecule metabolic process (GO:0044036)6.71915165
16cell wall macromolecule catabolic process (GO:0016998)6.71915165
17microtubule severing (GO:0051013)6.60143683
18cell-cell recognition (GO:0009988)6.51199168
19male meiosis (GO:0007140)6.48467025
20spermatid development (GO:0007286)6.32180576
21polyketide metabolic process (GO:0030638)6.30635505
22doxorubicin metabolic process (GO:0044598)6.30635505
23daunorubicin metabolic process (GO:0044597)6.30635505
24reproduction (GO:0000003)6.17911431
25acrosome reaction (GO:0007340)6.16787781
26epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.15504118
27synaptonemal complex organization (GO:0070193)5.93626840
28synaptonemal complex assembly (GO:0007130)5.77396893
29regulation of microtubule-based movement (GO:0060632)5.39507033
30single fertilization (GO:0007338)5.37259384
31regulation of response to osmotic stress (GO:0047484)5.28354617
32protein polyglutamylation (GO:0018095)5.01860184
33organic cation transport (GO:0015695)4.71504629
34fertilization (GO:0009566)4.59906124
35sperm capacitation (GO:0048240)4.56488298
36behavioral response to nicotine (GO:0035095)4.53636572
37DNA methylation involved in gamete generation (GO:0043046)4.35859040
38protein localization to cilium (GO:0061512)4.34420811
39response to pheromone (GO:0019236)4.23555116
40negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)4.18239137
41male meiosis I (GO:0007141)4.16186781
42protein localization to chromosome, centromeric region (GO:0071459)4.13401068
43spermatogenesis (GO:0007283)4.13236937
44male gamete generation (GO:0048232)4.11768238
45aminoglycoside antibiotic metabolic process (GO:0030647)4.07925394
46negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)4.04016677
47nuclear pore complex assembly (GO:0051292)4.01762558
48chromosome organization involved in meiosis (GO:0070192)3.99000942
49detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.98690131
50cilium morphogenesis (GO:0060271)3.98454936
51DNA replication-dependent nucleosome organization (GO:0034723)3.96900415
52DNA replication-dependent nucleosome assembly (GO:0006335)3.96900415
53meiotic nuclear division (GO:0007126)3.93839138
54protein localization to kinetochore (GO:0034501)3.93583471
55maintenance of protein location in nucleus (GO:0051457)3.92692707
56fucose catabolic process (GO:0019317)3.86264112
57L-fucose metabolic process (GO:0042354)3.86264112
58L-fucose catabolic process (GO:0042355)3.86264112
59muscle organ morphogenesis (GO:0048644)3.81428389
60seminiferous tubule development (GO:0072520)3.80828921
61negative regulation of epidermis development (GO:0045683)3.79973759
62gamete generation (GO:0007276)3.78841898
63negative regulation of inclusion body assembly (GO:0090084)3.74444366
64meiotic cell cycle (GO:0051321)3.73264196
65somite rostral/caudal axis specification (GO:0032525)3.73008348
66heterochromatin organization (GO:0070828)3.70720108
67nonmotile primary cilium assembly (GO:0035058)3.67060281
68negative regulation of cell cycle G2/M phase transition (GO:1902750)3.64897300
69germ cell development (GO:0007281)3.64106627
70chromosome condensation (GO:0030261)3.63344925
71cellular process involved in reproduction in multicellular organism (GO:0022412)3.57968306
72indole-containing compound catabolic process (GO:0042436)3.57924081
73indolalkylamine catabolic process (GO:0046218)3.57924081
74tryptophan catabolic process (GO:0006569)3.57924081
75mitotic sister chromatid segregation (GO:0000070)3.57152878
76neural tube formation (GO:0001841)3.56399969
77genitalia morphogenesis (GO:0035112)3.55841407
78meiosis I (GO:0007127)3.46852385
79cellular ketone body metabolic process (GO:0046950)3.45288683
80left/right axis specification (GO:0070986)3.42633261
81nuclear pore organization (GO:0006999)3.41684873
82water-soluble vitamin biosynthetic process (GO:0042364)3.40965024
83indolalkylamine metabolic process (GO:0006586)3.37831448
84hormone catabolic process (GO:0042447)3.37584278
85cornea development in camera-type eye (GO:0061303)3.36306286
86nucleoside diphosphate phosphorylation (GO:0006165)3.31813926
87photoreceptor cell maintenance (GO:0045494)3.30491815
88DNA packaging (GO:0006323)3.27746586
89intraciliary transport (GO:0042073)3.25585002
90axoneme assembly (GO:0035082)3.21501836
91ketone body metabolic process (GO:1902224)3.19669911
92microtubule depolymerization (GO:0007019)3.18872366
93cytidine metabolic process (GO:0046087)3.18245275
94cytidine catabolic process (GO:0006216)3.18245275
95cytidine deamination (GO:0009972)3.18245275
96C21-steroid hormone biosynthetic process (GO:0006700)3.17186223
97cellular component assembly involved in morphogenesis (GO:0010927)3.16775071
98rRNA transcription (GO:0009303)3.14484633
99retinal cone cell development (GO:0046549)3.14081545
100regulation of inclusion body assembly (GO:0090083)3.10770637
101histone H4-K5 acetylation (GO:0043981)3.10134847
102histone H4-K8 acetylation (GO:0043982)3.10134847
103regulation of mammary gland epithelial cell proliferation (GO:0033599)3.09292641
104kynurenine metabolic process (GO:0070189)3.09104225
105negative regulation of epidermal cell differentiation (GO:0045605)3.05572816
106regulation of telomere maintenance via telomerase (GO:0032210)3.05459754
107pore complex assembly (GO:0046931)3.03067183
108microtubule bundle formation (GO:0001578)2.99801513
109multicellular organismal reproductive process (GO:0048609)2.99784574
110glycolytic process (GO:0006096)2.98756996
111coenzyme catabolic process (GO:0009109)2.97111726
112left/right pattern formation (GO:0060972)2.96694421
113gene silencing by RNA (GO:0031047)2.95913301
114cilium organization (GO:0044782)2.94154454
115smoothened signaling pathway (GO:0007224)2.93872487
116pyrimidine nucleobase catabolic process (GO:0006208)2.93416226
117negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.93297759
118limb bud formation (GO:0060174)2.90908758
119cell recognition (GO:0008037)2.90510292
120sister chromatid segregation (GO:0000819)2.88421901
121tryptophan metabolic process (GO:0006568)2.86891301
122regulation of MHC class I biosynthetic process (GO:0045343)2.85911276
123GTP biosynthetic process (GO:0006183)2.82016274
124chromatin assembly (GO:0031497)2.81706168
125negative regulation of telomerase activity (GO:0051974)2.79891386
126progesterone metabolic process (GO:0042448)2.79470353
127cilium assembly (GO:0042384)2.78997196
128cellular biogenic amine catabolic process (GO:0042402)2.77889243
129amine catabolic process (GO:0009310)2.77889243
130transmission of nerve impulse (GO:0019226)2.76552145
131regulation of action potential (GO:0098900)2.76084028
132photoreceptor cell development (GO:0042461)2.75707709
133negative regulation of transcription regulatory region DNA binding (GO:2000678)2.73242801
134inner ear receptor stereocilium organization (GO:0060122)2.71454251
135platelet dense granule organization (GO:0060155)2.70034368
136indole-containing compound metabolic process (GO:0042430)2.68849701
137nucleobase catabolic process (GO:0046113)2.68493089
138determination of left/right symmetry (GO:0007368)2.67814895
139negative regulation of telomere maintenance (GO:0032205)2.67197932
140detection of light stimulus involved in sensory perception (GO:0050962)2.66300873
141detection of light stimulus involved in visual perception (GO:0050908)2.66300873
142G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.64289636
143neuronal action potential (GO:0019228)2.62476493
144gamma-aminobutyric acid transport (GO:0015812)2.61398012
145spinal cord motor neuron differentiation (GO:0021522)2.59678360
146preassembly of GPI anchor in ER membrane (GO:0016254)2.59147516
147negative regulation of cytosolic calcium ion concentration (GO:0051481)2.58663874
148regulation of collateral sprouting (GO:0048670)2.58581123
149centriole replication (GO:0007099)2.57608780
150behavioral response to ethanol (GO:0048149)2.56544222
151retinal rod cell development (GO:0046548)2.55916159
152benzene-containing compound metabolic process (GO:0042537)2.55864765
153respiratory chain complex IV assembly (GO:0008535)2.55368093
154reflex (GO:0060004)2.52781991
155exogenous drug catabolic process (GO:0042738)2.51744700
156cell projection assembly (GO:0030031)2.51448451
157determination of bilateral symmetry (GO:0009855)2.50407706
158synaptic transmission, cholinergic (GO:0007271)2.49452158
159protein complex biogenesis (GO:0070271)2.49161699
160adaptation of signaling pathway (GO:0023058)2.48624253
161sulfation (GO:0051923)2.47413084
162regulation of neurotransmitter uptake (GO:0051580)2.46789132
163eye photoreceptor cell development (GO:0042462)2.45801372
164nephron tubule morphogenesis (GO:0072078)2.44762093
165nephron epithelium morphogenesis (GO:0072088)2.44762093
166auditory receptor cell stereocilium organization (GO:0060088)2.44236791
167mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.43969543
168mitochondrial respiratory chain complex I assembly (GO:0032981)2.43969543
169NADH dehydrogenase complex assembly (GO:0010257)2.43969543
170positive regulation of oligodendrocyte differentiation (GO:0048714)2.42858864
171specification of symmetry (GO:0009799)2.42303266
172mannosylation (GO:0097502)2.39806254
173dopamine transport (GO:0015872)2.35370423
174embryonic epithelial tube formation (GO:0001838)2.33228975
175somite development (GO:0061053)2.32979448
176primary amino compound metabolic process (GO:1901160)2.32420029
177appendage development (GO:0048736)2.31312723
178limb development (GO:0060173)2.31312723
179GPI anchor metabolic process (GO:0006505)2.30694077
180cilium or flagellum-dependent cell motility (GO:0001539)10.6179210

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.40753027
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse4.26731624
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse4.26731624
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse4.26731624
5ZNF274_21170338_ChIP-Seq_K562_Hela3.83990020
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.78319617
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.35813288
8NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.92458577
9GBX2_23144817_ChIP-Seq_PC3_Human2.70088163
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.66141322
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.46134783
12TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.45216703
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.43225514
14SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.40384496
15IGF1R_20145208_ChIP-Seq_DFB_Human2.27538019
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.23737381
17HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.21175685
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.19980316
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.12261855
20FUS_26573619_Chip-Seq_HEK293_Human2.08937713
21RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.01134043
22P300_19829295_ChIP-Seq_ESCs_Human1.97708633
23TP63_19390658_ChIP-ChIP_HaCaT_Human1.95600672
24EWS_26573619_Chip-Seq_HEK293_Human1.93203669
25TAF15_26573619_Chip-Seq_HEK293_Human1.91392106
26GATA1_26923725_Chip-Seq_HPCs_Mouse1.90566298
27ELK4_26923725_Chip-Seq_MESODERM_Mouse1.85885679
28ER_23166858_ChIP-Seq_MCF-7_Human1.83546199
29FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.82109770
30PIAS1_25552417_ChIP-Seq_VCAP_Human1.79073136
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.71595300
32BCAT_22108803_ChIP-Seq_LS180_Human1.70081444
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68651932
34AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.68462618
35FOXM1_23109430_ChIP-Seq_U2OS_Human1.67933731
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.66581791
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.65873287
38EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.65406679
39* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.61995375
40STAT3_1855785_ChIP-Seq_MESCs_Mouse1.61972133
41E2F4_17652178_ChIP-ChIP_JURKAT_Human1.61872381
42TCF3_18692474_ChIP-Seq_MESCs_Mouse1.61546071
43SMAD4_21799915_ChIP-Seq_A2780_Human1.59657561
44SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.55728244
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.55216489
46CBP_20019798_ChIP-Seq_JUKART_Human1.55216489
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.53611989
48NR3C1_21868756_ChIP-Seq_MCF10A_Human1.53476490
49BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.53398385
50STAT3_23295773_ChIP-Seq_U87_Human1.53320481
51AR_25329375_ChIP-Seq_VCAP_Human1.52919195
52SALL1_21062744_ChIP-ChIP_HESCs_Human1.52395060
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50821255
54SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49807449
55FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.49076755
56E2F1_17053090_ChIP-ChIP_MCF-7_Human1.48788234
57MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.48301342
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.47244522
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.46075191
60KAP1_22055183_ChIP-Seq_ESCs_Mouse1.46017290
61TCF4_23295773_ChIP-Seq_U87_Human1.44971041
62NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.43430726
63CBX2_27304074_Chip-Seq_ESCs_Mouse1.43311931
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43178504
65YY1_22570637_ChIP-Seq_MALME-3M_Human1.42969890
66IRF1_19129219_ChIP-ChIP_H3396_Human1.41551100
67SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.41008868
68REST_21632747_ChIP-Seq_MESCs_Mouse1.40101563
69TP53_22573176_ChIP-Seq_HFKS_Human1.39623800
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39602500
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39602500
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.39523319
73PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.38864858
74E2F7_22180533_ChIP-Seq_HELA_Human1.38784009
75* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38525409
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.38424871
77SPI1_26923725_Chip-Seq_HPCs_Mouse1.36611456
78STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35832984
79RNF2_27304074_Chip-Seq_NSC_Mouse1.34465762
80NANOG_19829295_ChIP-Seq_ESCs_Human1.33864284
81SOX2_19829295_ChIP-Seq_ESCs_Human1.33864284
82TCF4_22108803_ChIP-Seq_LS180_Human1.33202040
83KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.32265975
84ESET_19884257_ChIP-Seq_ESCs_Mouse1.32031878
85FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31995521
86NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.31084042
87PCGF2_27294783_Chip-Seq_NPCs_Mouse1.30439253
88PCGF2_27294783_Chip-Seq_ESCs_Mouse1.30200325
89RUNX2_22187159_ChIP-Seq_PCA_Human1.30178533
90SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.29948852
91FOXA1_25329375_ChIP-Seq_VCAP_Human1.28929949
92FOXA1_27270436_Chip-Seq_PROSTATE_Human1.28929949
93SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.27990715
94SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.27990009
95CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25270369
96KLF5_20875108_ChIP-Seq_MESCs_Mouse1.24947114
97AR_21572438_ChIP-Seq_LNCaP_Human1.24655361
98POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.24607598
99SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22861184
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21341124
101KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.21087611
102PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.20771010
103SUZ12_27294783_Chip-Seq_NPCs_Mouse1.20267810
104NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.20266642
105AR_20517297_ChIP-Seq_VCAP_Human1.19260653
106SMAD4_21741376_ChIP-Seq_EPCs_Human1.18122939
107GATA3_21867929_ChIP-Seq_CD8_Mouse1.17766091
108RXRA_24833708_ChIP-Seq_LIVER_Mouse1.17678169
109NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.17551072
110ELF1_20517297_ChIP-Seq_JURKAT_Human1.17079385
111POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.17060698
112PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16898189
113NFE2_27457419_Chip-Seq_LIVER_Mouse1.15739136
114STAT3_18555785_ChIP-Seq_MESCs_Mouse1.15509559
115TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.14944169
116TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14375841
117TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.13817594
118EZH2_27294783_Chip-Seq_NPCs_Mouse1.12793156
119DROSHA_22980978_ChIP-Seq_HELA_Human1.12627675
120FOXA1_21572438_ChIP-Seq_LNCaP_Human1.12402678
121ETV2_25802403_ChIP-Seq_MESCs_Mouse1.12149495
122NCOR_22424771_ChIP-Seq_293T_Human1.12035527
123GABP_17652178_ChIP-ChIP_JURKAT_Human1.11992998
124SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11969846
125NANOG_18692474_ChIP-Seq_MESCs_Mouse1.11926726
126ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11430558
127GATA3_21878914_ChIP-Seq_MCF-7_Human1.11261665
128PRDM14_20953172_ChIP-Seq_ESCs_Human1.09746383
129NANOG_18555785_Chip-Seq_ESCs_Mouse1.09589636
130OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09243106
131MYC_18940864_ChIP-ChIP_HL60_Human1.08405801
132SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08277496
133EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06813213
134POU5F1_16518401_ChIP-PET_MESCs_Mouse1.06617194
135RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.06130055
136YY1_21170310_ChIP-Seq_MESCs_Mouse1.05269924
137CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05122425
138RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04967008
139HOXB7_26014856_ChIP-Seq_BT474_Human1.04715715
140E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.04196397
141POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.03020006
142PHF8_20622854_ChIP-Seq_HELA_Human1.02609871
143P53_22387025_ChIP-Seq_ESCs_Mouse1.02051077
144WDR5_24793694_ChIP-Seq_LNCAP_Human1.01829586
145MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.01335922
146FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00617863
147POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.00435153
148FLI1_21867929_ChIP-Seq_TH2_Mouse1.00202278
149* SOX2_22085726_ChIP-Seq_NPCs_Mouse0.99887155
150ETV1_20927104_ChIP-Seq_GIST48_Human0.99768154
151NANOG_18692474_ChIP-Seq_MEFs_Mouse0.99607361
152AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99270276
153CDX2_22108803_ChIP-Seq_LS180_Human0.98988782
154PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.98492953
155TAL1_26923725_Chip-Seq_HPCs_Mouse0.98355175
156RARB_24833708_ChIP-Seq_LIVER_Mouse0.98283815
157NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.96951398
158TBL1_22424771_ChIP-Seq_293T_Human0.96512718
159RARA_24833708_ChIP-Seq_LIVER_Mouse0.96447512
160* CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95977153
161ERG_20517297_ChIP-Seq_VCAP_Human0.95797033
162CRX_20693478_ChIP-Seq_RETINA_Mouse0.95387657
163MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.95329070
164FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95265298
165CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.94628452
166STAT3_18555785_Chip-Seq_ESCs_Mouse0.93737384
167EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91780976
168BCOR_27268052_Chip-Seq_Bcells_Human0.91752992
169VDR_22108803_ChIP-Seq_LS180_Human0.91280452
170NANOG_16518401_ChIP-PET_MESCs_Mouse0.91208586
171SMC4_20622854_ChIP-Seq_HELA_Human0.91133088
172SOX2_18692474_ChIP-Seq_MESCs_Mouse0.91083137
173CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91040629
174TCF3_18692474_ChIP-Seq_MEFs_Mouse0.90817527
175HIF1A_21447827_ChIP-Seq_MCF-7_Human0.87513842
176TET1_21451524_ChIP-Seq_MESCs_Mouse0.86641193
177ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.86426819
178STAT1_20625510_ChIP-Seq_HELA_Human0.84997097
179SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84143081
180EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.83704371
181TP53_22127205_ChIP-Seq_IMR90_Human0.83479346
182EZH2_22144423_ChIP-Seq_EOC_Human0.83477371
183MYC_27129775_Chip-Seq_CORNEA_Mouse0.81304240
184NANOG_20526341_ChIP-Seq_ESCs_Human0.80117050
185TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.79851357
186MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.79781283

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization9.25183181
2MP0002653_abnormal_ependyma_morphology3.95738026
3MP0003698_abnormal_male_reproductive3.76615015
4MP0003011_delayed_dark_adaptation3.75282898
5MP0001929_abnormal_gametogenesis3.57132195
6MP0008877_abnormal_DNA_methylation3.07105635
7MP0008057_abnormal_DNA_replication3.03923970
8MP0004264_abnormal_extraembryonic_tissu2.87763641
9MP0002210_abnormal_sex_determination2.51837884
10MP0002254_reproductive_system_inflammat2.47246832
11MP0005499_abnormal_olfactory_system2.45433154
12MP0005394_taste/olfaction_phenotype2.45433154
13MP0006292_abnormal_olfactory_placode2.43192876
14MP0003890_abnormal_embryonic-extraembry2.42217294
15MP0002102_abnormal_ear_morphology2.36100946
16MP0005551_abnormal_eye_electrophysiolog2.34536256
17MP0001145_abnormal_male_reproductive2.31466253
18MP0005670_abnormal_white_adipose2.26309569
19MP0001984_abnormal_olfaction2.14683191
20MP0003880_abnormal_central_pattern2.12317926
21MP0002161_abnormal_fertility/fecundity2.07016020
22MP0005623_abnormal_meninges_morphology2.02548281
23MP0000372_irregular_coat_pigmentation1.98314828
24MP0006276_abnormal_autonomic_nervous1.96876337
25MP0002332_abnormal_exercise_endurance1.96238405
26MP0002638_abnormal_pupillary_reflex1.96143299
27MP0005075_abnormal_melanosome_morpholog1.95282269
28MP0001968_abnormal_touch/_nociception1.93915901
29MP0005646_abnormal_pituitary_gland1.89617777
30MP0002938_white_spotting1.87359005
31MP0000653_abnormal_sex_gland1.84825151
32MP0004957_abnormal_blastocyst_morpholog1.79899990
33MP0003195_calcinosis1.78332023
34MP0008872_abnormal_physiological_respon1.76965709
35MP0000631_abnormal_neuroendocrine_gland1.75813403
36MP0009046_muscle_twitch1.75810144
37MP0006035_abnormal_mitochondrial_morpho1.73999588
38MP0006072_abnormal_retinal_apoptosis1.73833985
39MP0002736_abnormal_nociception_after1.73175215
40MP0004142_abnormal_muscle_tone1.69565317
41MP0009745_abnormal_behavioral_response1.66666198
42MP0001529_abnormal_vocalization1.65864797
43MP0002876_abnormal_thyroid_physiology1.64402238
44MP0002160_abnormal_reproductive_system1.64213692
45MP0005645_abnormal_hypothalamus_physiol1.61473618
46MP0001485_abnormal_pinna_reflex1.60279538
47MP0003122_maternal_imprinting1.58361868
48MP0000383_abnormal_hair_follicle1.56417693
49MP0001293_anophthalmia1.54398425
50MP0002234_abnormal_pharynx_morphology1.54312845
51MP0002837_dystrophic_cardiac_calcinosis1.53491184
52MP0000427_abnormal_hair_cycle1.52725421
53MP0005084_abnormal_gallbladder_morpholo1.51792866
54MP0001986_abnormal_taste_sensitivity1.51594530
55MP0000569_abnormal_digit_pigmentation1.47047492
56MP0004885_abnormal_endolymph1.46401364
57MP0001486_abnormal_startle_reflex1.45858323
58MP0003121_genomic_imprinting1.44377817
59MP0000566_synostosis1.44108674
60MP0005257_abnormal_intraocular_pressure1.43760111
61MP0004147_increased_porphyrin_level1.43641790
62MP0005380_embryogenesis_phenotype1.41217622
63MP0001672_abnormal_embryogenesis/_devel1.41217622
64MP0002272_abnormal_nervous_system1.40718455
65MP0004133_heterotaxia1.40639935
66MP0004858_abnormal_nervous_system1.39064028
67MP0003787_abnormal_imprinting1.38476545
68MP0002735_abnormal_chemical_nociception1.38309536
69MP0008058_abnormal_DNA_repair1.36233491
70MP0005171_absent_coat_pigmentation1.34418092
71MP0010094_abnormal_chromosome_stability1.33525341
72MP0005647_abnormal_sex_gland1.32938500
73MP0003646_muscle_fatigue1.32577271
74MP0003705_abnormal_hypodermis_morpholog1.32279449
75MP0002088_abnormal_embryonic_growth/wei1.31382156
76MP0003984_embryonic_growth_retardation1.30795416
77MP0000678_abnormal_parathyroid_gland1.27253274
78MP0002127_abnormal_cardiovascular_syste1.26340724
79MP0008995_early_reproductive_senescence1.24592828
80MP0002557_abnormal_social/conspecific_i1.21145169
81MP0002132_abnormal_respiratory_system1.21104133
82MP0001970_abnormal_pain_threshold1.19306589
83MP0003718_maternal_effect1.18924273
84MP0003950_abnormal_plasma_membrane1.18315977
85MP0002092_abnormal_eye_morphology1.17660825
86MP0010386_abnormal_urinary_bladder1.17516164
87MP0002572_abnormal_emotion/affect_behav1.16636535
88MP0000026_abnormal_inner_ear1.16516932
89MP0001501_abnormal_sleep_pattern1.15405026
90MP0000778_abnormal_nervous_system1.13215379
91MP0008007_abnormal_cellular_replicative1.12814160
92MP0002909_abnormal_adrenal_gland1.12129062
93MP0002064_seizures1.10687427
94MP0005266_abnormal_metabolism1.10588488
95MP0002734_abnormal_mechanical_nocicepti1.10393327
96MP0005195_abnormal_posterior_eye1.08679175
97MP0004043_abnormal_pH_regulation1.07745909
98MP0002970_abnormal_white_adipose1.05478397
99MP0002733_abnormal_thermal_nociception1.04911050
100MP0003077_abnormal_cell_cycle1.04861264
101MP0005408_hypopigmentation1.04528529
102MP0008961_abnormal_basal_metabolism1.04503036
103MP0003111_abnormal_nucleus_morphology1.04493505
104MP0003136_yellow_coat_color1.03472901
105MP0009780_abnormal_chondrocyte_physiolo1.02585912
106MP0004742_abnormal_vestibular_system1.02539020
107MP0006036_abnormal_mitochondrial_physio1.01857526
108MP0008789_abnormal_olfactory_epithelium1.00258476
109MP0002163_abnormal_gland_morphology0.98109069
110MP0001324_abnormal_eye_pigmentation0.97979724
111MP0000749_muscle_degeneration0.97298444
112MP0004924_abnormal_behavior0.97060948
113MP0005386_behavior/neurological_phenoty0.97060948
114MP0002095_abnormal_skin_pigmentation0.96423093
115MP0010030_abnormal_orbit_morphology0.95854568
116MP0002269_muscular_atrophy0.95713733
117MP0010352_gastrointestinal_tract_polyps0.95346644
118MP0004145_abnormal_muscle_electrophysio0.94724368
119MP0005174_abnormal_tail_pigmentation0.94666984
120MP0002067_abnormal_sensory_capabilities0.94613674
121MP0002233_abnormal_nose_morphology0.94268231
122MP0000358_abnormal_cell_content/0.93901800
123MP0002085_abnormal_embryonic_tissue0.93487442
124MP0001849_ear_inflammation0.92965800
125MP0002752_abnormal_somatic_nervous0.92499461
126MP0003878_abnormal_ear_physiology0.92141845
127MP0005377_hearing/vestibular/ear_phenot0.92141845
128MP0001963_abnormal_hearing_physiology0.91260359
129MP0005379_endocrine/exocrine_gland_phen0.91046985
130MP0002277_abnormal_respiratory_mucosa0.89920056
131MP0001730_embryonic_growth_arrest0.89880974
132MP0000647_abnormal_sebaceous_gland0.89582866
133MP0002084_abnormal_developmental_patter0.89547348
134MP0003123_paternal_imprinting0.88773879
135MP0003938_abnormal_ear_development0.88759486
136MP0003635_abnormal_synaptic_transmissio0.88064664
137MP0003183_abnormal_peptide_metabolism0.87216080
138MP0005391_vision/eye_phenotype0.86688923
139MP0002063_abnormal_learning/memory/cond0.86318533
140MP0002184_abnormal_innervation0.85903993
141MP0002932_abnormal_joint_morphology0.85545348
142MP0003786_premature_aging0.84041778
143MP0009115_abnormal_fat_cell0.83605020
144MP0003137_abnormal_impulse_conducting0.82284839
145MP0001919_abnormal_reproductive_system0.81241944
146MP0005389_reproductive_system_phenotype0.80662184
147MP0004381_abnormal_hair_follicle0.80480854
148MP0000762_abnormal_tongue_morphology0.80247476
149MP0003283_abnormal_digestive_organ0.79570055
150MP0000049_abnormal_middle_ear0.78484260
151MP0000350_abnormal_cell_proliferation0.78073356
152MP0005666_abnormal_adipose_tissue0.77998309
153MP0002928_abnormal_bile_duct0.77660641
154MP0002086_abnormal_extraembryonic_tissu0.77039527
155MP0002114_abnormal_axial_skeleton0.76880183
156MP0005319_abnormal_enzyme/_coenzyme0.76323290
157MP0000432_abnormal_head_morphology0.75703978
158MP0002139_abnormal_hepatobiliary_system0.70966585
159MP0000313_abnormal_cell_death0.70747419
160MP0001348_abnormal_lacrimal_gland0.67928911
161MP0003937_abnormal_limbs/digits/tail_de0.66805982
162MP0005365_abnormal_bile_salt0.65656736
163MP0001697_abnormal_embryo_size0.63946012
164MP0003315_abnormal_perineum_morphology0.62167012
165MP0002080_prenatal_lethality0.62083133
166MP0006082_CNS_inflammation0.61924740
167MP0002282_abnormal_trachea_morphology0.58973241
168MP0003935_abnormal_craniofacial_develop0.57890712
169MP0000428_abnormal_craniofacial_morphol0.57835547
170MP0004197_abnormal_fetal_growth/weight/0.57791782
171MP0008875_abnormal_xenobiotic_pharmacok0.57097780
172MP0005253_abnormal_eye_physiology0.56427058
173MP0003755_abnormal_palate_morphology0.56297290
174MP0008932_abnormal_embryonic_tissue0.56214707
175MP0003119_abnormal_digestive_system0.55108273

Predicted human phenotypes

RankGene SetZ-score
1Absent/shortened dynein arms (HP:0200106)8.66965683
2Dynein arm defect of respiratory motile cilia (HP:0012255)8.66965683
3Abnormal respiratory motile cilium physiology (HP:0012261)8.44470981
4Abnormal ciliary motility (HP:0012262)7.34060257
5Rhinitis (HP:0012384)6.92904995
6Abnormal respiratory motile cilium morphology (HP:0005938)6.72492117
7Abnormal respiratory epithelium morphology (HP:0012253)6.72492117
8Chronic bronchitis (HP:0004469)6.49176987
9Nasal polyposis (HP:0100582)6.36622860
10Abnormality of the lower motor neuron (HP:0002366)5.50243348
11Abnormality of the nasal mucosa (HP:0000433)5.17595520
12Pancreatic cysts (HP:0001737)4.82027198
13True hermaphroditism (HP:0010459)4.68931936
14Infertility (HP:0000789)4.56751162
15Bilateral microphthalmos (HP:0007633)4.11550632
16Bronchiectasis (HP:0002110)3.94251745
17Male infertility (HP:0003251)3.84944651
18Chronic hepatic failure (HP:0100626)3.68434196
19Bronchitis (HP:0012387)3.50178882
20Amyotrophic lateral sclerosis (HP:0007354)3.35104470
21Bile duct proliferation (HP:0001408)3.33292891
22Abnormal biliary tract physiology (HP:0012439)3.33292891
23Supernumerary spleens (HP:0009799)3.29631691
24Congenital stationary night blindness (HP:0007642)3.02167870
25Abnormality of the renal cortex (HP:0011035)2.98024668
26Bifid tongue (HP:0010297)2.94257251
27Abnormality of midbrain morphology (HP:0002418)2.92982273
28Molar tooth sign on MRI (HP:0002419)2.92982273
29Nephronophthisis (HP:0000090)2.86722717
30Aplasia/Hypoplasia of the tongue (HP:0010295)2.84435295
31Impulsivity (HP:0100710)2.83640944
32Hypochromic microcytic anemia (HP:0004840)2.78779066
33Gait imbalance (HP:0002141)2.77434502
34Multiple enchondromatosis (HP:0005701)2.73273366
35Sclerocornea (HP:0000647)2.73214714
36Congenital primary aphakia (HP:0007707)2.71282492
37Upper motor neuron abnormality (HP:0002127)2.69538732
38Facial cleft (HP:0002006)2.67013226
39Nephroblastoma (Wilms tumor) (HP:0002667)2.66782320
40Abnormal rod and cone electroretinograms (HP:0008323)2.63254757
41Type II lissencephaly (HP:0007260)2.60743718
42Hepatoblastoma (HP:0002884)2.60097423
43Rib fusion (HP:0000902)2.58190677
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.56133537
45Recurrent sinusitis (HP:0011108)2.52248244
46Nephrogenic diabetes insipidus (HP:0009806)2.50972809
47Attenuation of retinal blood vessels (HP:0007843)2.50044128
48Embryonal renal neoplasm (HP:0011794)2.45644574
49Progressive cerebellar ataxia (HP:0002073)2.42957924
50Male pseudohermaphroditism (HP:0000037)2.41043881
51Abnormality of the labia minora (HP:0012880)2.38786976
52Abolished electroretinogram (ERG) (HP:0000550)2.38611545
53Furrowed tongue (HP:0000221)2.37089925
54Hyperinsulinemic hypoglycemia (HP:0000825)2.33738812
55Genital tract atresia (HP:0001827)2.32221476
56Recurrent otitis media (HP:0000403)2.29867766
57Large for gestational age (HP:0001520)2.24595541
58Polydipsia (HP:0001959)2.24586636
59Abnormal drinking behavior (HP:0030082)2.24586636
60Postaxial foot polydactyly (HP:0001830)2.22715990
61Vaginal atresia (HP:0000148)2.20632993
62Short humerus (HP:0005792)2.19411124
63Medial flaring of the eyebrow (HP:0010747)2.16601557
64Aplasia/hypoplasia of the humerus (HP:0006507)2.16076871
65Decreased central vision (HP:0007663)2.09202628
66Poor coordination (HP:0002370)2.05101341
67Abnormality of the renal medulla (HP:0100957)2.03364786
68Partial duplication of thumb phalanx (HP:0009944)2.03080823
69Bony spicule pigmentary retinopathy (HP:0007737)2.02915592
70Congenital hepatic fibrosis (HP:0002612)2.00122009
71Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.4869980
72Tubulointerstitial nephritis (HP:0001970)1.99792243
73Chromosomal breakage induced by crosslinking agents (HP:0003221)1.99134277
74Spastic tetraparesis (HP:0001285)1.98322084
75Cerebellar dysplasia (HP:0007033)1.97156919
76Neoplasm of striated muscle (HP:0009728)1.96986063
77Gaze-evoked nystagmus (HP:0000640)1.96875881
78Abnormality of the phalanges of the hallux (HP:0010057)1.94306565
79Preaxial hand polydactyly (HP:0001177)1.93372011
80Ependymoma (HP:0002888)1.93322896
81Impaired proprioception (HP:0010831)1.92902280
82Methylmalonic acidemia (HP:0002912)1.92614569
83Lissencephaly (HP:0001339)1.91490522
84Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.91210342
85Abnormality of alanine metabolism (HP:0010916)1.91210342
86Hyperalaninemia (HP:0003348)1.91210342
87Increased corneal curvature (HP:0100692)1.90789906
88Keratoconus (HP:0000563)1.90789906
89Congenital, generalized hypertrichosis (HP:0004540)1.90233602
90Gastrointestinal atresia (HP:0002589)1.88335701
91Intestinal atresia (HP:0011100)1.88041157
92Tongue fasciculations (HP:0001308)1.87669896
93Acute necrotizing encephalopathy (HP:0006965)1.86603238
94Rhabdomyosarcoma (HP:0002859)1.86431957
95Inability to walk (HP:0002540)1.86010664
96Chronic sinusitis (HP:0011109)1.83488397
97Rectovaginal fistula (HP:0000143)1.83154799
98Rectal fistula (HP:0100590)1.83154799
99Broad-based gait (HP:0002136)1.81927169
100Genetic anticipation (HP:0003743)1.81914746
101Abnormal lung lobation (HP:0002101)1.80809560
102Oculomotor apraxia (HP:0000657)1.80792599
103Hemiparesis (HP:0001269)1.79923323
104Aplasia/Hypoplasia of the spleen (HP:0010451)1.79654668
105Progressive inability to walk (HP:0002505)1.78004007
106Polyuria (HP:0000103)1.77900115
107Oligodactyly (hands) (HP:0001180)1.76686567
108Absent speech (HP:0001344)1.76248609
109Sloping forehead (HP:0000340)1.76240466
110Acute encephalopathy (HP:0006846)1.75630084
111Ragged-red muscle fibers (HP:0003200)1.75199452
112Retinitis pigmentosa (HP:0000510)1.74868176
113Chorioretinal atrophy (HP:0000533)1.74843797
114Partial duplication of the phalanx of hand (HP:0009999)1.72990359
115Optic nerve hypoplasia (HP:0000609)1.72287830
116Atrophy/Degeneration involving motor neurons (HP:0007373)1.71229173
117Renal cortical cysts (HP:0000803)1.71206384
118Asplenia (HP:0001746)1.71128497
119Decreased circulating renin level (HP:0003351)1.70652150
120Concave nail (HP:0001598)1.70540948
121Testicular atrophy (HP:0000029)1.70224578
122Mitochondrial inheritance (HP:0001427)1.70205353
123Abnormality of dentin (HP:0010299)1.69505797
124Hyperglycinuria (HP:0003108)1.68781175
125Abnormality of the corticospinal tract (HP:0002492)1.68759599
126Pancreatic fibrosis (HP:0100732)1.67991927
127Muscle fibrillation (HP:0010546)1.67828905
128Occipital encephalocele (HP:0002085)1.67807484
129Fibular hypoplasia (HP:0003038)1.66447145
130Aplasia/Hypoplasia of the tibia (HP:0005772)1.65900141
131Progressive macrocephaly (HP:0004481)1.64973294
132Optic disc pallor (HP:0000543)1.64898787
133Increased CSF lactate (HP:0002490)1.64382323
134Aganglionic megacolon (HP:0002251)1.64259079
135Postaxial hand polydactyly (HP:0001162)1.63902581
136Pachygyria (HP:0001302)1.62526595
137Hypopigmentation of the fundus (HP:0007894)1.61961979
138Vaginal fistula (HP:0004320)1.61695671
139Cystic liver disease (HP:0006706)1.61441483
140Missing ribs (HP:0000921)1.61102465
141Narrow forehead (HP:0000341)1.61067918
142Chromsome breakage (HP:0040012)1.59799260
143Dandy-Walker malformation (HP:0001305)1.59540577
144Aplasia/Hypoplasia of the uvula (HP:0010293)1.59245622
145Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.58840265
146Abnormal spermatogenesis (HP:0008669)1.58136036
147Tubular atrophy (HP:0000092)1.58033871
148Hypoplasia of the fovea (HP:0007750)1.56701548
149Aplasia/Hypoplasia of the fovea (HP:0008060)1.56701548
150EMG: neuropathic changes (HP:0003445)1.56691686
151Anomalous pulmonary venous return (HP:0010772)1.56582131
152Progressive external ophthalmoplegia (HP:0000590)1.56349462
153Difficulty walking (HP:0002355)1.55917875
154Abnormality of the anterior horn cell (HP:0006802)1.54967053
155Degeneration of anterior horn cells (HP:0002398)1.54967053
156Hand muscle atrophy (HP:0009130)1.53861229
157Anencephaly (HP:0002323)1.53059631
158Meckel diverticulum (HP:0002245)1.52831684
159Dyschromatopsia (HP:0007641)1.52357808
160Intestinal fistula (HP:0100819)1.51187281
161Recurrent bronchitis (HP:0002837)1.50846812
162Sensory axonal neuropathy (HP:0003390)1.49464001
163Tubulointerstitial abnormality (HP:0001969)1.49174384
164Abnormality of the musculature of the hand (HP:0001421)1.48472530
165Microretrognathia (HP:0000308)1.47371341
166Pendular nystagmus (HP:0012043)1.45697374
167Abnormal cartilage morphology (HP:0002763)1.45677791
168Broad foot (HP:0001769)1.45540103
169Hyperventilation (HP:0002883)1.44927504

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.33770313
2PDK36.33770313
3CDK125.52005602
4FRK5.08042969
5PDK24.02609025
6GRK53.89247986
7GRK13.18115223
8GRK62.96521679
9WNK32.83386577
10MAP4K22.63218520
11ERN12.61605072
12INSRR2.61064662
13ADRBK22.52457656
14BMPR1B2.46114219
15TTK2.44159331
16TESK12.38101321
17PRKD32.31009961
18CASK2.16763396
19TYRO32.13304032
20ICK2.06378787
21MAPK132.02614844
22WNK12.00012654
23ZAK1.91648191
24TNIK1.90577216
25TRIM281.89222167
26NUAK11.88759692
27MAP3K41.85724356
28OXSR11.85319458
29TLK11.78325085
30ACVR1B1.77523661
31CSF1R1.74924589
32TGFBR21.69280542
33STK101.58657823
34MST41.56270829
35NEK21.53266251
36TAOK31.52364212
37WNK41.43027631
38MAP2K71.39691354
39PTK2B1.37011342
40PAK31.34585841
41MARK11.34237383
42GRK71.30907463
43MAPK71.27958582
44FGFR21.24928526
45STK391.23985487
46WEE11.21158986
47CHEK21.20219645
48DYRK21.15910970
49DAPK21.14055441
50CAMKK21.12823527
51MOS1.11774935
52MAPK151.06569548
53STK381.05289520
54PLK11.03732648
55PRKG21.02246905
56BCR1.01161153
57STK38L1.00795203
58ERBB30.99813641
59MATK0.99615955
60CDK190.99542017
61PNCK0.98399903
62PRKCE0.92756810
63OBSCN0.89298914
64TGFBR10.88108485
65CDK70.87452549
66BRSK20.87142499
67MAP3K100.83978779
68CHEK10.81520819
69NME10.79982858
70PLK20.79973471
71CSNK1G20.77570175
72STK30.77378107
73MUSK0.74777092
74MAP2K60.73085250
75EPHA40.71930358
76CSNK1G10.71501609
77DYRK1B0.70983843
78CDC70.70865634
79FER0.70562988
80MKNK20.70160202
81CAMK40.69871181
82PAK40.69582511
83MARK20.69335926
84CAMK1G0.68688280
85NTRK20.68469138
86CSNK1G30.68160076
87DYRK30.66470796
88PHKG20.66081270
89PHKG10.66081270
90TIE10.64535462
91PKN10.62741108
92NTRK30.62398880
93NTRK10.60277961
94CAMK10.60221266
95NLK0.59551043
96CSNK1A1L0.59054433
97VRK10.58133223
98CAMK2A0.58107718
99MAP2K40.57758870
100STK110.56940593
101ADRBK10.56257928
102EPHA20.55191736
103MTOR0.52662150
104MAPKAPK30.52326085
105EPHA30.52259818
106RPS6KA50.51169657
107IRAK10.50741818
108PRKACA0.50573065
109PDK10.50462488
110CSNK1A10.49959063
111PRKAA20.48856878
112PINK10.47869135
113CAMK1D0.47539422
114STK160.47311395
115SGK20.46805483
116AURKA0.44912961
117PRKAA10.44121337
118ATM0.43800155
119EPHB20.43747593
120BCKDK0.42877913
121ERBB20.41424982
122PRKCG0.41423983
123BUB10.40951711
124AKT20.40579001
125TNK20.40421926
126PRKCZ0.39913811
127AKT30.39688968
128PRKCQ0.39117750
129PAK10.38579042
130PLK40.38269061
131IKBKB0.37515308
132FGFR30.37477843
133PRKCA0.37200518
134CDK40.36649436
135SGK2230.36421751
136SGK4940.36421751
137DYRK1A0.36091875
138LATS20.36069108
139CHUK0.35954118
140EIF2AK20.35491020
141PLK30.34823751
142MAPKAPK50.34153542
143PAK60.32316400
144EIF2AK30.32034506
145CSK0.31730841
146PASK0.31211892
147HIPK20.30919678
148CDK20.29982980
149IGF1R0.26940446
150ATR0.26915902
151BRSK10.24569426
152AURKB0.22787769
153ALK0.22633562
154CDK10.22171877
155MAPK120.21535265
156PRKACG0.20311429
157PRKCI0.19750700
158EEF2K0.19593962
159CSNK1E0.14676813
160PTK20.13344110
161SRPK10.12535600
162CDC42BPA0.11887751
163MAPK100.11670713
164LATS10.11664127
165CCNB10.11381644
166GSK3B0.11103398
167PAK20.10741436
168LMTK20.10091854
169GSK3A0.09664423
170RIPK10.09134478
171MAPK10.08536046
172PRKACB0.07737550
173RPS6KB20.06601450
174MAP3K70.06575831
175PRKCD0.06554151

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007507.60525432
2Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.26463457
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.05279878
4Fructose and mannose metabolism_Homo sapiens_hsa000513.01972728
5Linoleic acid metabolism_Homo sapiens_hsa005912.78268462
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.73579984
7Pyruvate metabolism_Homo sapiens_hsa006202.67140826
8Phototransduction_Homo sapiens_hsa047442.64052514
9Propanoate metabolism_Homo sapiens_hsa006402.56622386
10Butanoate metabolism_Homo sapiens_hsa006502.54310000
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.53261875
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.49385544
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.49144277
14Nitrogen metabolism_Homo sapiens_hsa009102.48141690
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.35100785
16Protein export_Homo sapiens_hsa030602.33443640
17Fanconi anemia pathway_Homo sapiens_hsa034602.30849327
18Oxidative phosphorylation_Homo sapiens_hsa001902.30108020
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.27435433
20Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.12547477
21Maturity onset diabetes of the young_Homo sapiens_hsa049502.11938924
22Pentose phosphate pathway_Homo sapiens_hsa000302.01126239
23Arachidonic acid metabolism_Homo sapiens_hsa005902.01009299
24Nicotine addiction_Homo sapiens_hsa050331.92547488
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.88119921
26Fatty acid biosynthesis_Homo sapiens_hsa000611.82341050
27Carbon metabolism_Homo sapiens_hsa012001.81466446
28Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.75097851
29Parkinsons disease_Homo sapiens_hsa050121.74456699
30Selenocompound metabolism_Homo sapiens_hsa004501.74329987
31Basal transcription factors_Homo sapiens_hsa030221.72148242
32Glycerolipid metabolism_Homo sapiens_hsa005611.68777740
33Pentose and glucuronate interconversions_Homo sapiens_hsa000401.68544788
34PPAR signaling pathway_Homo sapiens_hsa033201.66199502
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.65939100
36Caffeine metabolism_Homo sapiens_hsa002321.65640561
37RNA transport_Homo sapiens_hsa030131.61704694
38Olfactory transduction_Homo sapiens_hsa047401.47644127
39Galactose metabolism_Homo sapiens_hsa000521.47027273
40Histidine metabolism_Homo sapiens_hsa003401.45543885
41Glycerophospholipid metabolism_Homo sapiens_hsa005641.42625313
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.38645199
43beta-Alanine metabolism_Homo sapiens_hsa004101.37322934
44mRNA surveillance pathway_Homo sapiens_hsa030151.33383662
45Chemical carcinogenesis_Homo sapiens_hsa052041.29359104
46Glucagon signaling pathway_Homo sapiens_hsa049221.29286305
47Taste transduction_Homo sapiens_hsa047421.29131480
48Biosynthesis of amino acids_Homo sapiens_hsa012301.27570003
49RNA polymerase_Homo sapiens_hsa030201.24305124
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.21994492
51Morphine addiction_Homo sapiens_hsa050321.17679967
52Ether lipid metabolism_Homo sapiens_hsa005651.12823689
53Huntingtons disease_Homo sapiens_hsa050161.11070735
54Alzheimers disease_Homo sapiens_hsa050101.09097690
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.08306613
56Insulin secretion_Homo sapiens_hsa049111.08056202
57Glycosaminoglycan degradation_Homo sapiens_hsa005311.07908080
58Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00592233
59Ovarian steroidogenesis_Homo sapiens_hsa049130.99381225
60Serotonergic synapse_Homo sapiens_hsa047260.98365952
61Collecting duct acid secretion_Homo sapiens_hsa049660.97427109
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97161577
63Homologous recombination_Homo sapiens_hsa034400.94392025
64Fatty acid degradation_Homo sapiens_hsa000710.92702815
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90797207
66Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.90196949
67Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.89933334
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.88676421
69Steroid biosynthesis_Homo sapiens_hsa001000.87867189
70GABAergic synapse_Homo sapiens_hsa047270.87020290
71Fat digestion and absorption_Homo sapiens_hsa049750.85776014
72Fatty acid metabolism_Homo sapiens_hsa012120.85405088
73Tryptophan metabolism_Homo sapiens_hsa003800.85350064
74Oocyte meiosis_Homo sapiens_hsa041140.84935870
75Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84718162
76Cell cycle_Homo sapiens_hsa041100.83449319
77Circadian entrainment_Homo sapiens_hsa047130.82609402
78Glutamatergic synapse_Homo sapiens_hsa047240.80874333
79Salivary secretion_Homo sapiens_hsa049700.78782190
80RNA degradation_Homo sapiens_hsa030180.76224099
81Regulation of autophagy_Homo sapiens_hsa041400.76191248
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.75523688
83Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.73945009
84Cardiac muscle contraction_Homo sapiens_hsa042600.72756609
85Dorso-ventral axis formation_Homo sapiens_hsa043200.70597380
86Central carbon metabolism in cancer_Homo sapiens_hsa052300.69857143
87Glutathione metabolism_Homo sapiens_hsa004800.68699355
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66465921
89Retinol metabolism_Homo sapiens_hsa008300.65284758
90AMPK signaling pathway_Homo sapiens_hsa041520.65195331
91Circadian rhythm_Homo sapiens_hsa047100.63628374
92Purine metabolism_Homo sapiens_hsa002300.62284234
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.61124005
94Hedgehog signaling pathway_Homo sapiens_hsa043400.61017540
95Complement and coagulation cascades_Homo sapiens_hsa046100.60900736
96Metabolic pathways_Homo sapiens_hsa011000.60762034
97Pyrimidine metabolism_Homo sapiens_hsa002400.55822969
98Cocaine addiction_Homo sapiens_hsa050300.55127646
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.54275095
100Calcium signaling pathway_Homo sapiens_hsa040200.53891773
101Sulfur metabolism_Homo sapiens_hsa009200.53761364
102Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52585078
103Mineral absorption_Homo sapiens_hsa049780.52128253
104ABC transporters_Homo sapiens_hsa020100.51602883
105Inositol phosphate metabolism_Homo sapiens_hsa005620.50060316
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49834875
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.49457223
108Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.48824025
109Sulfur relay system_Homo sapiens_hsa041220.48449682
110Intestinal immune network for IgA production_Homo sapiens_hsa046720.47470309
111Dopaminergic synapse_Homo sapiens_hsa047280.45124230
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.44973402
113Basal cell carcinoma_Homo sapiens_hsa052170.44748023
114mTOR signaling pathway_Homo sapiens_hsa041500.43965954
115Sphingolipid metabolism_Homo sapiens_hsa006000.43087102
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39645306
117Renin-angiotensin system_Homo sapiens_hsa046140.39386988
1182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.39350258
119Arginine and proline metabolism_Homo sapiens_hsa003300.38819687
120cAMP signaling pathway_Homo sapiens_hsa040240.37759997
121Amphetamine addiction_Homo sapiens_hsa050310.35815964
122Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.34249916
123Base excision repair_Homo sapiens_hsa034100.33805894
124Peroxisome_Homo sapiens_hsa041460.33111306
125DNA replication_Homo sapiens_hsa030300.32768332
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31201835
127Vitamin digestion and absorption_Homo sapiens_hsa049770.31023148
128Long-term depression_Homo sapiens_hsa047300.30431177
129Bile secretion_Homo sapiens_hsa049760.29264072
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28848911
131Vascular smooth muscle contraction_Homo sapiens_hsa042700.28438523
132Tight junction_Homo sapiens_hsa045300.28301583
133SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27562343
134Pancreatic secretion_Homo sapiens_hsa049720.26679210
135Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26542880
136p53 signaling pathway_Homo sapiens_hsa041150.26186395
137Antigen processing and presentation_Homo sapiens_hsa046120.25695937
138Protein digestion and absorption_Homo sapiens_hsa049740.24995918
139Steroid hormone biosynthesis_Homo sapiens_hsa001400.23930364
140Tyrosine metabolism_Homo sapiens_hsa003500.21357313
141Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.21233921
142Folate biosynthesis_Homo sapiens_hsa007900.20673667
143One carbon pool by folate_Homo sapiens_hsa006700.19890854
144Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.19827414
145Lysine degradation_Homo sapiens_hsa003100.19101364
146Nucleotide excision repair_Homo sapiens_hsa034200.18982283
147Phosphatidylinositol signaling system_Homo sapiens_hsa040700.18951555
148Spliceosome_Homo sapiens_hsa030400.18007412
149Mismatch repair_Homo sapiens_hsa034300.16966045
150Hippo signaling pathway_Homo sapiens_hsa043900.16910927
151Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.16607354
152Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.14799794

Most similar genes based on co-expression Upload to Enrichr

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