WDYHV1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.75172020
2DNA deamination (GO:0045006)5.58972693
3telomere maintenance via semi-conservative replication (GO:0032201)4.21384948
4deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.19970179
5proteasome assembly (GO:0043248)4.13831813
6DNA strand elongation involved in DNA replication (GO:0006271)4.06976692
7DNA strand elongation (GO:0022616)3.97839251
8viral transcription (GO:0019083)3.96045245
9establishment of protein localization to mitochondrial membrane (GO:0090151)3.91535615
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.89054543
11SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.83058328
12translational termination (GO:0006415)3.82589462
13telomere maintenance via recombination (GO:0000722)3.78441698
14cotranslational protein targeting to membrane (GO:0006613)3.75837844
15protein targeting to ER (GO:0045047)3.71176070
16translational elongation (GO:0006414)3.63164047
17maturation of SSU-rRNA (GO:0030490)3.57159918
18mitotic recombination (GO:0006312)3.56638888
19protein localization to endoplasmic reticulum (GO:0070972)3.52252934
20establishment of protein localization to endoplasmic reticulum (GO:0072599)3.49668382
21establishment of integrated proviral latency (GO:0075713)3.47827713
22DNA double-strand break processing (GO:0000729)3.45017588
23ATP synthesis coupled proton transport (GO:0015986)3.42366805
24energy coupled proton transport, down electrochemical gradient (GO:0015985)3.42366805
25DNA damage response, detection of DNA damage (GO:0042769)3.32138178
26chaperone-mediated protein transport (GO:0072321)3.30854947
27regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.27913131
28replication fork processing (GO:0031297)3.25735782
29telomere maintenance via telomere lengthening (GO:0010833)3.25114901
30formation of translation preinitiation complex (GO:0001731)3.24734681
31pseudouridine synthesis (GO:0001522)3.19827470
32histone exchange (GO:0043486)3.19549973
33DNA replication initiation (GO:0006270)3.19403973
34respiratory chain complex IV assembly (GO:0008535)3.19346053
35ribosomal small subunit biogenesis (GO:0042274)3.17492764
36antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.16576022
37antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.16576022
38mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.16370224
39exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.14637531
40CENP-A containing nucleosome assembly (GO:0034080)3.13486946
41purine deoxyribonucleotide catabolic process (GO:0009155)3.12862318
42nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.12047616
43protein-cofactor linkage (GO:0018065)3.11725516
44regulation of nuclear cell cycle DNA replication (GO:0033262)3.11716322
45protein complex biogenesis (GO:0070271)3.09288466
46regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.08569570
47regulation of mitotic spindle checkpoint (GO:1903504)3.08569570
48mitochondrial respiratory chain complex assembly (GO:0033108)3.08144058
49positive regulation of gamma-delta T cell activation (GO:0046645)3.07821511
50viral life cycle (GO:0019058)3.05181586
51translational initiation (GO:0006413)3.02967123
52nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.02462219
53synapsis (GO:0007129)3.02170842
54cellular protein complex disassembly (GO:0043624)3.02023772
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.01333922
56DNA replication-dependent nucleosome assembly (GO:0006335)3.00879280
57DNA replication-dependent nucleosome organization (GO:0034723)3.00879280
58centriole replication (GO:0007099)3.00812548
59oxidative phosphorylation (GO:0006119)3.00114733
60positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.00094804
61translation (GO:0006412)2.96677024
62peptidyl-histidine modification (GO:0018202)2.94564490
63nucleotide-excision repair, DNA gap filling (GO:0006297)2.94400362
64mitotic metaphase plate congression (GO:0007080)2.93354650
65chromatin remodeling at centromere (GO:0031055)2.92739855
66antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.91508753
67L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.90250706
68antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.90121248
69establishment of viral latency (GO:0019043)2.89267931
70ribosome biogenesis (GO:0042254)2.88870902
71transcription-coupled nucleotide-excision repair (GO:0006283)2.88863961
72ribonucleoprotein complex biogenesis (GO:0022613)2.87331497
73protein K6-linked ubiquitination (GO:0085020)2.86139615
74metaphase plate congression (GO:0051310)2.86038886
75platelet dense granule organization (GO:0060155)2.85965581
76telomere organization (GO:0032200)2.84084507
77response to interferon-beta (GO:0035456)2.84007215
78telomere maintenance (GO:0000723)2.82428969
79DNA catabolic process, exonucleolytic (GO:0000738)2.82353232
80somatic hypermutation of immunoglobulin genes (GO:0016446)2.81535154
81somatic diversification of immune receptors via somatic mutation (GO:0002566)2.81535154
82DNA replication-independent nucleosome organization (GO:0034724)2.81034278
83DNA replication-independent nucleosome assembly (GO:0006336)2.81034278
84negative regulation of DNA-dependent DNA replication (GO:2000104)2.80086917
85respiratory electron transport chain (GO:0022904)2.79770832
86deoxyribonucleotide catabolic process (GO:0009264)2.78843233
87iron-sulfur cluster assembly (GO:0016226)2.78750215
88metallo-sulfur cluster assembly (GO:0031163)2.78750215
89mitochondrial respiratory chain complex I assembly (GO:0032981)2.78599588
90NADH dehydrogenase complex assembly (GO:0010257)2.78599588
91mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.78599588
92resolution of meiotic recombination intermediates (GO:0000712)2.78554629
93antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.78457261
94antigen processing and presentation via MHC class Ib (GO:0002475)2.78301328
95regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.77339620
96nucleobase biosynthetic process (GO:0046112)2.76121719
97electron transport chain (GO:0022900)2.76067762
98deoxyribose phosphate catabolic process (GO:0046386)2.75603464
99regulation of centriole replication (GO:0046599)2.72828246
100ribosomal large subunit biogenesis (GO:0042273)2.71866392
101positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.71865480
102protein complex disassembly (GO:0043241)2.71304247
103rRNA modification (GO:0000154)2.71187506
104RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.70773602
105tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.70773602
106protein neddylation (GO:0045116)2.70429715
107purine-containing compound salvage (GO:0043101)2.70289271
108DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.69986682
109cellular response to interferon-beta (GO:0035458)2.69960570
110negative regulation of ligase activity (GO:0051352)2.69534521
111negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.69534521
112somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.69020009
113isotype switching (GO:0045190)2.69020009
114somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.69020009
115anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.68526333
116purine nucleobase biosynthetic process (GO:0009113)2.68295515
117signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.68247210
118intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.68247210
119signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.67668963
120signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.67668963
121signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.67668963
122guanosine-containing compound biosynthetic process (GO:1901070)2.67587394
123transcription elongation from RNA polymerase III promoter (GO:0006385)2.67079622
124termination of RNA polymerase III transcription (GO:0006386)2.67079622
125positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.66857955
126protein deneddylation (GO:0000338)2.66808563
127IMP biosynthetic process (GO:0006188)2.66448583
128deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.65824615
129postreplication repair (GO:0006301)2.65532964
130maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.65414104
131DNA replication checkpoint (GO:0000076)2.65119817
132mast cell activation (GO:0045576)2.64507438
133antigen processing and presentation of endogenous antigen (GO:0019883)2.63496037
134signal peptide processing (GO:0006465)2.61184249
135cullin deneddylation (GO:0010388)2.60798354
136telomere maintenance via telomerase (GO:0007004)2.60538414
137macromolecular complex disassembly (GO:0032984)2.59779569
138regulation of helicase activity (GO:0051095)2.59641696
139recombinational repair (GO:0000725)2.59300112
140ubiquinone metabolic process (GO:0006743)2.58777660
141DNA unwinding involved in DNA replication (GO:0006268)2.57900967
142rRNA processing (GO:0006364)2.57713001
143nuclear-transcribed mRNA catabolic process (GO:0000956)2.57094400
144pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.57058587
145negative regulation of meiosis (GO:0045835)2.56033490
146polyketide metabolic process (GO:0030638)2.55937229
147doxorubicin metabolic process (GO:0044598)2.55937229
148daunorubicin metabolic process (GO:0044597)2.55937229
149cytochrome complex assembly (GO:0017004)2.55932422
150double-strand break repair via homologous recombination (GO:0000724)2.55299592
151regulation of mitochondrial translation (GO:0070129)2.55112816
152regulation of meiosis I (GO:0060631)2.54185991
153regulation of cellular amino acid metabolic process (GO:0006521)2.53634064
154signal transduction involved in DNA integrity checkpoint (GO:0072401)2.53312609
155positive regulation of ligase activity (GO:0051351)2.52555641
156inner mitochondrial membrane organization (GO:0007007)2.52178305
157signal transduction involved in cell cycle checkpoint (GO:0072395)2.51108631
158ubiquinone biosynthetic process (GO:0006744)2.50541796
159signal transduction involved in DNA damage checkpoint (GO:0072422)2.50165804
160protein K11-linked ubiquitination (GO:0070979)2.48331915
161DNA ligation (GO:0006266)2.47973086
162spliceosomal snRNP assembly (GO:0000387)2.47937054
163kinetochore organization (GO:0051383)2.47843201
164nonmotile primary cilium assembly (GO:0035058)2.47174583

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.94625052
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.73849828
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.47787960
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.47778587
5ELF1_17652178_ChIP-ChIP_JURKAT_Human3.33309857
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.20541982
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.07296091
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.03261200
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.90731866
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.76522433
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.71064116
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.63027118
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.60550753
14* VDR_23849224_ChIP-Seq_CD4+_Human2.59365436
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.52513356
16FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.50370526
17IRF8_22096565_ChIP-ChIP_GC-B_Human2.44710012
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.41395247
19ZNF274_21170338_ChIP-Seq_K562_Hela2.38736234
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.34345524
21VDR_22108803_ChIP-Seq_LS180_Human2.34188759
22IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.29213026
23MYC_19030024_ChIP-ChIP_MESCs_Mouse2.26238261
24* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.25214895
25FOXP3_21729870_ChIP-Seq_TREG_Human2.24850817
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.24265952
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.16851668
28MYC_19079543_ChIP-ChIP_MESCs_Mouse2.10962688
29SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.10713066
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.08934549
31HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.08260901
32HOXB4_20404135_ChIP-ChIP_EML_Mouse2.01986032
33* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.00280110
34SRF_21415370_ChIP-Seq_HL-1_Mouse1.98303895
35MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.95761326
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.94254854
37ERG_20887958_ChIP-Seq_HPC-7_Mouse1.93589867
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.93536543
39EWS_26573619_Chip-Seq_HEK293_Human1.92739699
40FUS_26573619_Chip-Seq_HEK293_Human1.91649097
41DCP1A_22483619_ChIP-Seq_HELA_Human1.89843123
42SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.88909969
43XRN2_22483619_ChIP-Seq_HELA_Human1.88440677
44CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.87951453
45GABP_19822575_ChIP-Seq_HepG2_Human1.85638458
46PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77473281
47NELFA_20434984_ChIP-Seq_ESCs_Mouse1.77250926
48CIITA_25753668_ChIP-Seq_RAJI_Human1.74004008
49SCL_19346495_ChIP-Seq_HPC-7_Human1.72337698
50SPI1_23547873_ChIP-Seq_NB4_Human1.71377576
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.63030972
52GATA1_22025678_ChIP-Seq_K562_Human1.62727579
53GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.62659697
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.60249940
55TAF15_26573619_Chip-Seq_HEK293_Human1.59626445
56ELK1_19687146_ChIP-ChIP_HELA_Human1.59236595
57IRF8_21731497_ChIP-ChIP_J774_Mouse1.58668282
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.58042250
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57729575
60FOXM1_23109430_ChIP-Seq_U2OS_Human1.57335169
61STAT4_19710469_ChIP-ChIP_TH1__Mouse1.54273558
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53097707
63IGF1R_20145208_ChIP-Seq_DFB_Human1.53012748
64LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52359598
65TTF2_22483619_ChIP-Seq_HELA_Human1.51617053
66MYC_22102868_ChIP-Seq_BL_Human1.51057199
67NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.47311924
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44142533
69KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.43554727
70ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43419587
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.42124410
72E2F1_21310950_ChIP-Seq_MCF-7_Human1.42035123
73IRF1_19129219_ChIP-ChIP_H3396_Human1.41827065
74ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.41048236
75POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.40044369
76HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.39495839
77MYB_21317192_ChIP-Seq_ERMYB_Mouse1.39168651
78MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.38796720
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.38122802
80EGR1_19374776_ChIP-ChIP_THP-1_Human1.37761885
81P300_19829295_ChIP-Seq_ESCs_Human1.35923722
82MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.34770361
83ZFX_18555785_ChIP-Seq_MESCs_Mouse1.34763862
84VDR_21846776_ChIP-Seq_THP-1_Human1.33899891
85MYCN_18555785_ChIP-Seq_MESCs_Mouse1.32547622
86AR_21909140_ChIP-Seq_LNCAP_Human1.32325953
87YY1_21170310_ChIP-Seq_MESCs_Mouse1.30380231
88CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.30306585
89STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.28567281
90SOX2_16153702_ChIP-ChIP_HESCs_Human1.28151191
91MYB_26560356_Chip-Seq_TH2_Human1.26884295
92PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25725368
93GBX2_23144817_ChIP-Seq_PC3_Human1.25593639
94CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25508286
95NANOG_16153702_ChIP-ChIP_HESCs_Human1.24992638
96POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.24985840
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.23360662
98YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.23044775
99CTBP2_25329375_ChIP-Seq_LNCAP_Human1.22521255
100* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.21040668
101MYB_26560356_Chip-Seq_TH1_Human1.18457148
102CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18442725
103NANOG_18555785_ChIP-Seq_MESCs_Mouse1.17730218
104MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.14563177
105RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13140486
106* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12966633
107GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12046523
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11230252
109MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09571283
110KDM5A_27292631_Chip-Seq_BREAST_Human1.04899023
111FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.04162512
112GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.03791412
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01361927
114* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.01347078
115PADI4_21655091_ChIP-ChIP_MCF-7_Human1.01107835
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.00890902
117E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.00361389
118* RUNX1_22412390_ChIP-Seq_EML_Mouse1.00304336
119TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99173828
120ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.97919513
121HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.97842961
122E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97689529
123* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96168534
124MYC_18940864_ChIP-ChIP_HL60_Human0.94281167
125TP53_22573176_ChIP-Seq_HFKS_Human0.92589060
126CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92555515
127MAF_26560356_Chip-Seq_TH1_Human0.92503148
128RBPJ_22232070_ChIP-Seq_NCS_Mouse0.92118966
129ER_23166858_ChIP-Seq_MCF-7_Human0.90961651
130VDR_24763502_ChIP-Seq_THP-1_Human0.90453708
131TFEB_21752829_ChIP-Seq_HELA_Human0.90432603
132ELK1_22589737_ChIP-Seq_MCF10A_Human0.89148125
133NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.88890094
134SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88443310
135SUZ12_27294783_Chip-Seq_NPCs_Mouse0.88231127
136* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.87887970
137* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87250608
138* CBP_20019798_ChIP-Seq_JUKART_Human0.87250608
139FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.86425142
140SOX17_20123909_ChIP-Seq_XEN_Mouse0.84846164
141NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.84028018
142PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.83876748
143SOX2_18555785_ChIP-Seq_MESCs_Mouse0.83804709
144CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.83797100
145SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.83028049

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system4.19256109
2MP0002938_white_spotting3.13208379
3MP0003763_abnormal_thymus_physiology3.12444107
4MP0003693_abnormal_embryo_hatching2.93328329
5MP0002102_abnormal_ear_morphology2.92306401
6MP0001835_abnormal_antigen_presentation2.91987265
7MP0005671_abnormal_response_to2.86256582
8MP0008057_abnormal_DNA_replication2.67388773
9MP0010094_abnormal_chromosome_stability2.66751391
10MP0009785_altered_susceptibility_to2.61069868
11MP0000685_abnormal_immune_system2.61023098
12MP0004957_abnormal_blastocyst_morpholog2.53283562
13MP0008007_abnormal_cellular_replicative2.46110379
14MP0008058_abnormal_DNA_repair2.43071888
15MP0001529_abnormal_vocalization2.38603194
16MP0003111_abnormal_nucleus_morphology2.23918300
17MP0004808_abnormal_hematopoietic_stem2.21863088
18MP0003077_abnormal_cell_cycle2.19557540
19MP0002398_abnormal_bone_marrow2.18933324
20MP0003880_abnormal_central_pattern2.13709350
21MP0006072_abnormal_retinal_apoptosis2.07921072
22MP0005174_abnormal_tail_pigmentation2.06763700
23MP0001188_hyperpigmentation2.05679084
24MP0009379_abnormal_foot_pigmentation2.04585765
25MP0009333_abnormal_splenocyte_physiolog2.03326120
26MP0002420_abnormal_adaptive_immunity2.01139268
27MP0004147_increased_porphyrin_level2.00450943
28MP0005025_abnormal_response_to2.00359589
29MP0001800_abnormal_humoral_immune1.99092135
30MP0008789_abnormal_olfactory_epithelium1.97459161
31MP0001819_abnormal_immune_cell1.97086483
32MP0000689_abnormal_spleen_morphology1.95700978
33MP0002723_abnormal_immune_serum1.94487677
34MP0005075_abnormal_melanosome_morpholog1.94230635
35MP0005000_abnormal_immune_tolerance1.87073152
36MP0003436_decreased_susceptibility_to1.84371060
37MP0002452_abnormal_antigen_presenting1.83554727
38MP0002148_abnormal_hypersensitivity_rea1.83115954
39MP0003121_genomic_imprinting1.82931912
40MP0006036_abnormal_mitochondrial_physio1.82237619
41MP0005397_hematopoietic_system_phenotyp1.82095287
42MP0001545_abnormal_hematopoietic_system1.82095287
43MP0002722_abnormal_immune_system1.81502182
44MP0000490_abnormal_crypts_of1.80160500
45MP0000716_abnormal_immune_system1.80101904
46MP0002405_respiratory_system_inflammati1.77093676
47MP0002166_altered_tumor_susceptibility1.76555382
48MP0003718_maternal_effect1.73132378
49MP0003890_abnormal_embryonic-extraembry1.73097432
50MP0005464_abnormal_platelet_physiology1.72815872
51MP0001873_stomach_inflammation1.70967631
52MP0003724_increased_susceptibility_to1.70916990
53MP0001986_abnormal_taste_sensitivity1.69075963
54MP0002429_abnormal_blood_cell1.68257448
55MP0003787_abnormal_imprinting1.68023234
56MP0002638_abnormal_pupillary_reflex1.64971380
57MP0001853_heart_inflammation1.63230170
58MP0001293_anophthalmia1.61714497
59MP0002419_abnormal_innate_immunity1.60160872
60MP0002736_abnormal_nociception_after1.58495054
61MP0005499_abnormal_olfactory_system1.56530889
62MP0005394_taste/olfaction_phenotype1.56530889
63MP0005387_immune_system_phenotype1.55011222
64MP0001790_abnormal_immune_system1.55011222
65MP0003866_abnormal_defecation1.54644448
66MP0000703_abnormal_thymus_morphology1.54238418
67MP0003136_yellow_coat_color1.52339385
68MP0003786_premature_aging1.51968341
69MP0002006_tumorigenesis1.49968335
70MP0000465_gastrointestinal_hemorrhage1.49522926
71MP0002019_abnormal_tumor_incidence1.48969945
72MP0010155_abnormal_intestine_physiology1.46800433
73MP0002160_abnormal_reproductive_system1.46590186
74MP0003937_abnormal_limbs/digits/tail_de1.46221957
75MP0005084_abnormal_gallbladder_morpholo1.45823853
76MP0002751_abnormal_autonomic_nervous1.45425774
77MP0003186_abnormal_redox_activity1.45278124
78MP0006054_spinal_hemorrhage1.38009914
79MP0002837_dystrophic_cardiac_calcinosis1.37669006
80MP0000647_abnormal_sebaceous_gland1.37640115
81MP0002234_abnormal_pharynx_morphology1.37176666
82MP0001845_abnormal_inflammatory_respons1.36118945
83MP0005253_abnormal_eye_physiology1.35441299
84MP0002095_abnormal_skin_pigmentation1.32028334
85MP0002132_abnormal_respiratory_system1.31223789
86MP0009697_abnormal_copulation1.29628967
87MP0000427_abnormal_hair_cycle1.29492709
88MP0001984_abnormal_olfaction1.23018642
89MP0000015_abnormal_ear_pigmentation1.21720122
90MP0000858_altered_metastatic_potential1.20681188
91MP0008877_abnormal_DNA_methylation1.19527688
92MP0004133_heterotaxia1.18143567
93MP0003122_maternal_imprinting1.16520892
94MP0010030_abnormal_orbit_morphology1.15820730
95MP0006276_abnormal_autonomic_nervous1.15588187
96MP0002233_abnormal_nose_morphology1.15382596
97MP0003195_calcinosis1.13377827
98MP0005551_abnormal_eye_electrophysiolog1.13219874
99MP0005360_urolithiasis1.11618546
100MP0008469_abnormal_protein_level1.11410798
101MP0003567_abnormal_fetal_cardiomyocyte1.10673309
102MP0008932_abnormal_embryonic_tissue1.10113241
103MP0002210_abnormal_sex_determination1.10111921
104MP0001968_abnormal_touch/_nociception1.08304691
105MP0001485_abnormal_pinna_reflex1.06203847
106MP0003119_abnormal_digestive_system1.05480103
107MP0000049_abnormal_middle_ear1.05261043
108MP0001929_abnormal_gametogenesis1.04757522
109MP0000313_abnormal_cell_death1.03847061
110MP0002653_abnormal_ependyma_morphology1.00879385
111MP0005257_abnormal_intraocular_pressure1.00829927
112MP0002282_abnormal_trachea_morphology1.00611564
113MP0001286_abnormal_eye_development0.99566227
114MP0001324_abnormal_eye_pigmentation0.98824109
115MP0001764_abnormal_homeostasis0.98564033
116MP0000631_abnormal_neuroendocrine_gland0.97191335
117MP0006035_abnormal_mitochondrial_morpho0.96577226
118MP0003123_paternal_imprinting0.96575165
119MP0005389_reproductive_system_phenotype0.95125508
120MP0004782_abnormal_surfactant_physiolog0.95067423
121MP0003656_abnormal_erythrocyte_physiolo0.95010294
122MP0000538_abnormal_urinary_bladder0.94866384
123MP0003755_abnormal_palate_morphology0.94493400
124MP0003941_abnormal_skin_development0.94171980
125MP0000778_abnormal_nervous_system0.93957320
126MP0001697_abnormal_embryo_size0.92811552
127MP0000653_abnormal_sex_gland0.91772484
128MP0002933_joint_inflammation0.91616972
129MP0005391_vision/eye_phenotype0.91536142
130MP0002272_abnormal_nervous_system0.90790540
131MP0001145_abnormal_male_reproductive0.90369186
132MP0002697_abnormal_eye_size0.89796539
133MP0004215_abnormal_myocardial_fiber0.89500903
134MP0005220_abnormal_exocrine_pancreas0.85736984
135MP0003183_abnormal_peptide_metabolism0.84816499
136MP0000350_abnormal_cell_proliferation0.84751040
137MP0009046_muscle_twitch0.83961801
138MP0008995_early_reproductive_senescence0.83521971
139MP0000343_altered_response_to0.80986823
140MP0000566_synostosis0.80617741
141MP0002693_abnormal_pancreas_physiology0.80431952
142MP0001299_abnormal_eye_distance/0.79657901
143MP0009764_decreased_sensitivity_to0.78938165
144MP0008004_abnormal_stomach_pH0.78739995
145MP0002084_abnormal_developmental_patter0.78275078
146MP0003878_abnormal_ear_physiology0.77639676
147MP0005377_hearing/vestibular/ear_phenot0.77639676
148MP0002734_abnormal_mechanical_nocicepti0.76191508
149MP0002085_abnormal_embryonic_tissue0.76164320
150MP0000358_abnormal_cell_content/0.76000258
151MP0002184_abnormal_innervation0.75572115
152MP0003861_abnormal_nervous_system0.75450220
153MP0001919_abnormal_reproductive_system0.75442380
154MP0004142_abnormal_muscle_tone0.74086122
155MP0003938_abnormal_ear_development0.73823521
156MP0002735_abnormal_chemical_nociception0.72611624
157MP0005380_embryogenesis_phenotype0.71734531
158MP0001672_abnormal_embryogenesis/_devel0.71734531
159MP0005646_abnormal_pituitary_gland0.71103963
160MP0003806_abnormal_nucleotide_metabolis0.70250115
161MP0001533_abnormal_skeleton_physiology0.69869659
162MP0003943_abnormal_hepatobiliary_system0.69179296
163MP0003221_abnormal_cardiomyocyte_apopto0.69002548
164MP0004264_abnormal_extraembryonic_tissu0.67688740
165MP0008873_increased_physiological_sensi0.64082576
166MP0006292_abnormal_olfactory_placode0.64066156
167MP0001663_abnormal_digestive_system0.63741427
168MP0000372_irregular_coat_pigmentation0.63185023
169MP0004947_skin_inflammation0.61728454
170MP0009278_abnormal_bone_marrow0.60813967
171MP0009765_abnormal_xenobiotic_induced0.59955397
172MP0001119_abnormal_female_reproductive0.59589882
173MP0005165_increased_susceptibility_to0.57927489
174MP0002876_abnormal_thyroid_physiology0.57772772
175MP0005379_endocrine/exocrine_gland_phen0.57641001

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)4.71738449
2Abnormal number of erythroid precursors (HP:0012131)4.46388657
3Abnormality of cells of the erythroid lineage (HP:0012130)4.30606790
4IgM deficiency (HP:0002850)3.85027658
5Type I transferrin isoform profile (HP:0003642)3.56299708
6Elevated erythrocyte sedimentation rate (HP:0003565)3.50149788
7Thrombocytosis (HP:0001894)3.49946772
8B lymphocytopenia (HP:0010976)3.47993693
9Abnormality of B cell number (HP:0010975)3.47993693
10Muscle fiber atrophy (HP:0100295)3.46511481
11Type 2 muscle fiber atrophy (HP:0003554)3.43245437
12Abnormality of the labia minora (HP:0012880)3.37941844
13Reticulocytopenia (HP:0001896)3.33486691
14Reduced antithrombin III activity (HP:0001976)3.20636191
15Colon cancer (HP:0003003)3.16564907
16Petechiae (HP:0000967)3.10442871
17Progressive macrocephaly (HP:0004481)2.97497934
18Recurrent bronchitis (HP:0002837)2.94275914
19Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.91930094
20Abnormal protein N-linked glycosylation (HP:0012347)2.91930094
21Abnormal protein glycosylation (HP:0012346)2.91930094
22Abnormal glycosylation (HP:0012345)2.91930094
23Chronic otitis media (HP:0000389)2.91345216
24Hepatocellular necrosis (HP:0001404)2.87267089
25Decreased activity of mitochondrial respiratory chain (HP:0008972)2.86072232
26Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.86072232
27Myositis (HP:0100614)2.83932788
28IgG deficiency (HP:0004315)2.78839815
29Panhypogammaglobulinemia (HP:0003139)2.77133005
30Chromosomal breakage induced by crosslinking agents (HP:0003221)2.77018867
31Hepatic necrosis (HP:0002605)2.75384574
32Lymphoma (HP:0002665)2.71369053
33Meckel diverticulum (HP:0002245)2.71111326
34Methylmalonic acidemia (HP:0002912)2.67066272
35Increased hepatocellular lipid droplets (HP:0006565)2.66801384
36Abnormality of T cell physiology (HP:0011840)2.65835775
37Recurrent abscess formation (HP:0002722)2.61900603
38Abnormality of the ileum (HP:0001549)2.59631771
39Oral leukoplakia (HP:0002745)2.59541577
40Abnormality of T cells (HP:0002843)2.59235426
41Birth length less than 3rd percentile (HP:0003561)2.56599737
42Aplasia/Hypoplasia of the uvula (HP:0010293)2.56179908
43Poor head control (HP:0002421)2.55838228
44Microretrognathia (HP:0000308)2.55241352
45Severe combined immunodeficiency (HP:0004430)2.53125649
46Medial flaring of the eyebrow (HP:0010747)2.51985177
47Pallor (HP:0000980)2.50402192
48Chromsome breakage (HP:0040012)2.49451666
49Abnormality of glycolysis (HP:0004366)2.46813070
503-Methylglutaconic aciduria (HP:0003535)2.43672645
51Mitochondrial inheritance (HP:0001427)2.42258984
52Aplasia/Hypoplasia of the sacrum (HP:0008517)2.40838929
53Hypoplastic pelvis (HP:0008839)2.40376933
54Recurrent viral infections (HP:0004429)2.39997556
55Abnormal mitochondria in muscle tissue (HP:0008316)2.39594558
56Abnormality of chromosome stability (HP:0003220)2.39470903
57Abnormality of the heme biosynthetic pathway (HP:0010472)2.39176678
58Abnormality of midbrain morphology (HP:0002418)2.36092175
59Molar tooth sign on MRI (HP:0002419)2.36092175
60Cerebral edema (HP:0002181)2.35740478
61Increased serum pyruvate (HP:0003542)2.35065149
62Acute necrotizing encephalopathy (HP:0006965)2.32390922
6311 pairs of ribs (HP:0000878)2.31326342
64Short tibia (HP:0005736)2.31158659
65Macrocytic anemia (HP:0001972)2.29996247
66Horseshoe kidney (HP:0000085)2.27796976
67Increased CSF lactate (HP:0002490)2.27215897
68Lipid accumulation in hepatocytes (HP:0006561)2.26526812
69Neuroendocrine neoplasm (HP:0100634)2.26052473
70Lymphopenia (HP:0001888)2.25342888
71T lymphocytopenia (HP:0005403)2.25225363
72Myelodysplasia (HP:0002863)2.24945171
73Bronchitis (HP:0012387)2.24801549
74Self-mutilation (HP:0000742)2.23939325
75Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.23708722
76Abnormality of alanine metabolism (HP:0010916)2.23708722
77Hyperalaninemia (HP:0003348)2.23708722
78Intestinal atresia (HP:0011100)2.23175916
79Renal Fanconi syndrome (HP:0001994)2.22002065
80Abnormality of methionine metabolism (HP:0010901)2.21082509
81Severe visual impairment (HP:0001141)2.21018721
82Increased serum lactate (HP:0002151)2.20849583
83Combined immunodeficiency (HP:0005387)2.18107860
84Hypoplasia of the thymus (HP:0000778)2.17803707
85Pancytopenia (HP:0001876)2.14742880
86Pustule (HP:0200039)2.13795485
87Acute lymphatic leukemia (HP:0006721)2.13375962
88Gait imbalance (HP:0002141)2.13361017
89Pendular nystagmus (HP:0012043)2.13115126
90Agnosia (HP:0010524)2.12561928
91Prolonged bleeding time (HP:0003010)2.12257184
92Abnormality of cells of the lymphoid lineage (HP:0012140)2.12218219
93Nephronophthisis (HP:0000090)2.12093819
94Microvesicular hepatic steatosis (HP:0001414)2.11566415
95Thyroiditis (HP:0100646)2.10996891
96Aplasia/Hypoplasia of the tibia (HP:0005772)2.10568974
97Recurrent bacterial skin infections (HP:0005406)2.10466006
98Pancreatic fibrosis (HP:0100732)2.10022134
99Abnormal lung lobation (HP:0002101)2.08767434
100Granulocytopenia (HP:0001913)2.06900084
101Amaurosis fugax (HP:0100576)2.06899545
102Septo-optic dysplasia (HP:0100842)2.05742403
103Abnormality of T cell number (HP:0011839)2.04978144
104Lactic acidosis (HP:0003128)2.04589154
105Aplasia/Hypoplasia of the fovea (HP:0008060)2.03602271
106Hypoplasia of the fovea (HP:0007750)2.03602271
107Congenital primary aphakia (HP:0007707)2.02726395
108Recurrent fungal infections (HP:0002841)2.02589862
109Optic nerve coloboma (HP:0000588)2.02587266
110Abnormality of aspartate family amino acid metabolism (HP:0010899)2.01754814
111Methylmalonic aciduria (HP:0012120)2.01500867
112Hypothermia (HP:0002045)2.01164966
113Ependymoma (HP:0002888)2.01162033
114Pancreatic cysts (HP:0001737)1.99066373
115Optic nerve hypoplasia (HP:0000609)1.97610301
116True hermaphroditism (HP:0010459)1.96563541
117Medulloblastoma (HP:0002885)1.96474194
118Basal cell carcinoma (HP:0002671)1.96223932
119Adrenal hypoplasia (HP:0000835)1.95599725
120Nephrogenic diabetes insipidus (HP:0009806)1.95578071
121Abnormality of the anterior horn cell (HP:0006802)1.94993096
122Degeneration of anterior horn cells (HP:0002398)1.94993096
123Hyperglycinemia (HP:0002154)1.94269515
124Erythema (HP:0010783)1.94044251
125Anophthalmia (HP:0000528)1.93374032
126Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.92180937
127Exercise intolerance (HP:0003546)1.91282405
128Oligodactyly (hands) (HP:0001180)1.90964778
129Small intestinal stenosis (HP:0012848)1.90726086
130Duodenal stenosis (HP:0100867)1.90726086
131Abnormality of the duodenum (HP:0002246)1.90369229
132Tongue fasciculations (HP:0001308)1.90142014
133Abnormality of the preputium (HP:0100587)1.89601107
134Nasal polyposis (HP:0100582)1.88670332
135Bone marrow hypocellularity (HP:0005528)1.86413263
136Aplasia/Hypoplasia of the tongue (HP:0010295)1.85071738
137Abnormality of eosinophils (HP:0001879)1.84835451
138Vaginal atresia (HP:0000148)1.84575940
139Broad face (HP:0000283)1.84303654
140Large eyes (HP:0001090)1.84003748
141Abnormality of the fovea (HP:0000493)1.83626894
142Lissencephaly (HP:0001339)1.82606748
143Genital tract atresia (HP:0001827)1.82493212
144Meningitis (HP:0001287)1.81629969
145Abnormality of serum amino acid levels (HP:0003112)1.81618141
146Aplasia/hypoplasia of the uterus (HP:0008684)1.81572319
147Premature graying of hair (HP:0002216)1.80316426
148Hypoglycemic coma (HP:0001325)1.80145656
149Pheochromocytoma (HP:0002666)1.79974918
150Abnormality of the nasal mucosa (HP:0000433)1.79196789
151Neutropenia (HP:0001875)1.79007796
152Gastrointestinal stroma tumor (HP:0100723)1.78649150
153Generalized aminoaciduria (HP:0002909)1.78406404
154Acute encephalopathy (HP:0006846)1.77597433
155Optic disc pallor (HP:0000543)1.77356921
156Respiratory difficulties (HP:0002880)1.76772023
157Poor suck (HP:0002033)1.76742704
158Sloping forehead (HP:0000340)1.75674437
159Sclerocornea (HP:0000647)1.74724543
160Rhabdomyosarcoma (HP:0002859)1.74066502
161Neoplasm of the peripheral nervous system (HP:0100007)1.73816619
162Stenosis of the external auditory canal (HP:0000402)1.73188137
163Supernumerary spleens (HP:0009799)1.71469991
164Absent thumb (HP:0009777)1.70434185
165Triphalangeal thumb (HP:0001199)1.69204631
166Respiratory failure (HP:0002878)1.67802754
167Volvulus (HP:0002580)1.66439896
168Absent radius (HP:0003974)1.65960904
169Preaxial hand polydactyly (HP:0001177)1.65621357

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE13.83971202
2STK163.35509218
3VRK23.11266992
4BRSK23.07613624
5FLT33.00614354
6KIT2.77973637
7NME22.60271190
8BMPR1B2.48129239
9ZAP702.43026932
10TEC2.40645337
11BUB12.40476150
12WNK32.35939584
13TXK2.29591053
14TRIM282.26912369
15BCKDK2.23028028
16VRK12.15885601
17MAP3K122.15757349
18EIF2AK32.15437375
19MAP4K12.10465172
20EIF2AK12.08722989
21BTK1.93045698
22PBK1.83338710
23FRK1.81239262
24CDK191.74781002
25GRK11.65685828
26PNCK1.62896485
27CCNB11.61128644
28MAP3K61.53599945
29CDC71.51262559
30TIE11.50457124
31STK391.48581502
32ACVR1B1.46878808
33MAP2K31.45006065
34MAP4K21.44676488
35CASK1.41020103
36BCR1.38802770
37SCYL21.38385935
38BRSK11.36566094
39TAF11.36414727
40DYRK31.35702587
41LIMK11.30403202
42WNK41.30356996
43NUAK11.28624452
44CSF1R1.26958401
45TYK21.26206288
46NEK21.25562158
47SYK1.24536042
48STK101.19936899
49IRAK41.19374950
50TSSK61.19368536
51MAP3K41.17587284
52TNIK1.16586058
53PASK1.15434551
54DYRK21.10540431
55KDR1.08461842
56IRAK31.07874543
57MAPK131.07691598
58TNK21.06703134
59SIK31.06677079
60PIM21.06505351
61SRPK11.06238141
62MKNK11.06005377
63JAK31.01809560
64ITK1.01565668
65TGFBR11.00083393
66STK38L0.99212852
67PAK30.98488723
68ATR0.97008239
69TBK10.96241773
70OXSR10.95166395
71AURKB0.91573508
72TGFBR20.91248614
73NME10.90922612
74EPHA40.90160543
75PLK20.89720494
76ADRBK20.89579341
77LRRK20.89370407
78CSNK1G10.88359730
79IKBKE0.87874102
80CSNK1G20.87527835
81PLK10.87474135
82CSNK1G30.86890434
83MARK30.86861322
84RPS6KA40.84521545
85NLK0.81681189
86ZAK0.81617672
87RPS6KB20.81064554
88PKN20.77378130
89DAPK10.75421242
90CDK70.74947327
91MKNK20.74203010
92TLK10.73598324
93LCK0.72598603
94PLK40.72561479
95EPHB20.72529513
96TESK20.72222036
97LYN0.72180558
98MARK10.72087966
99MAPKAPK30.70550450
100CSNK1A1L0.69620114
101NEK10.69416230
102CDK80.69211717
103CLK10.68960162
104MAP3K140.68299101
105MAP2K60.65489174
106PIM10.65485814
107MAP3K110.65410157
108CAMKK20.65308277
109PRKCG0.64216023
110CDK40.62710866
111INSRR0.62240716
112PDK20.61495555
113EIF2AK20.59499467
114PRKCE0.59130979
115BLK0.58702797
116TAOK30.58467141
117PHKG20.57143873
118PHKG10.57143873
119TESK10.56889768
120MATK0.56848203
121MAP3K50.56577147
122STK40.55114703
123GRK60.54059749
124ILK0.53247874
125MUSK0.51150222
126FGFR10.51021900
127PRKCI0.50998257
128MST40.49636725
129ATM0.49618430
130TAOK20.49130142
131CSNK2A10.48502085
132PINK10.47858163
133TTK0.45996142
134FGFR20.45445692
135IKBKB0.45237111
136MYLK0.44774098
137FER0.43310786
138CHEK10.41818268
139ERBB40.41457207
140PLK30.41117879
141MET0.39976567
142CSNK2A20.39047781
143PKN10.38966582
144MAP2K70.37833178
145ERN10.37718543
146STK30.36416481
147CHEK20.36345623
148AURKA0.36309613
149PAK40.35815477
150ERBB30.35160598

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.62842281
2Ribosome_Homo sapiens_hsa030103.99246157
3Mismatch repair_Homo sapiens_hsa034303.73005359
4Proteasome_Homo sapiens_hsa030503.33590496
5RNA polymerase_Homo sapiens_hsa030203.01088136
6Homologous recombination_Homo sapiens_hsa034402.86516510
7Protein export_Homo sapiens_hsa030602.86451642
8Base excision repair_Homo sapiens_hsa034102.76518681
9Nucleotide excision repair_Homo sapiens_hsa034202.60825999
10Pyrimidine metabolism_Homo sapiens_hsa002402.52019017
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.42305109
12Primary immunodeficiency_Homo sapiens_hsa053402.39392523
13Spliceosome_Homo sapiens_hsa030402.33790173
14Steroid biosynthesis_Homo sapiens_hsa001002.17855828
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.08493440
16Propanoate metabolism_Homo sapiens_hsa006401.94935039
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.88578922
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.74228744
19Cell cycle_Homo sapiens_hsa041101.68888417
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.68753600
21Fatty acid elongation_Homo sapiens_hsa000621.68359273
22RNA transport_Homo sapiens_hsa030131.67352030
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.65854168
24Non-homologous end-joining_Homo sapiens_hsa034501.57709620
25Fanconi anemia pathway_Homo sapiens_hsa034601.56781788
26RNA degradation_Homo sapiens_hsa030181.56102689
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.54814432
28Basal transcription factors_Homo sapiens_hsa030221.54548904
29Purine metabolism_Homo sapiens_hsa002301.47373152
30Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46052701
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.40309360
32Selenocompound metabolism_Homo sapiens_hsa004501.34766480
33Antigen processing and presentation_Homo sapiens_hsa046121.33797892
34Parkinsons disease_Homo sapiens_hsa050121.31484608
35One carbon pool by folate_Homo sapiens_hsa006701.30477981
36Butanoate metabolism_Homo sapiens_hsa006501.29837701
37Hematopoietic cell lineage_Homo sapiens_hsa046401.28714598
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.24964056
39Herpes simplex infection_Homo sapiens_hsa051681.24178731
40Folate biosynthesis_Homo sapiens_hsa007901.23910887
41Pyruvate metabolism_Homo sapiens_hsa006201.23070036
42Legionellosis_Homo sapiens_hsa051341.16065094
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.13885686
44Oxidative phosphorylation_Homo sapiens_hsa001901.12633485
45Epstein-Barr virus infection_Homo sapiens_hsa051691.09956015
46RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.08616853
47N-Glycan biosynthesis_Homo sapiens_hsa005101.08524640
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08512594
49SNARE interactions in vesicular transport_Homo sapiens_hsa041301.06150611
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04715797
51Cardiac muscle contraction_Homo sapiens_hsa042601.03333611
52Phototransduction_Homo sapiens_hsa047441.01702637
53Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.01430881
54Measles_Homo sapiens_hsa051621.01232362
55NF-kappa B signaling pathway_Homo sapiens_hsa040641.00043616
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.96608853
57p53 signaling pathway_Homo sapiens_hsa041150.96372424
58Peroxisome_Homo sapiens_hsa041460.93896275
59Fatty acid metabolism_Homo sapiens_hsa012120.92943745
60Sulfur metabolism_Homo sapiens_hsa009200.90665842
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.90267837
62Oocyte meiosis_Homo sapiens_hsa041140.89603459
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.88726791
64Intestinal immune network for IgA production_Homo sapiens_hsa046720.85575139
65Glutathione metabolism_Homo sapiens_hsa004800.85319439
66Huntingtons disease_Homo sapiens_hsa050160.83024664
67Pentose phosphate pathway_Homo sapiens_hsa000300.82794147
68Leishmaniasis_Homo sapiens_hsa051400.82425455
69Tryptophan metabolism_Homo sapiens_hsa003800.77470793
70Other glycan degradation_Homo sapiens_hsa005110.76132645
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75659961
72Nitrogen metabolism_Homo sapiens_hsa009100.74014114
73Biosynthesis of amino acids_Homo sapiens_hsa012300.73193597
74Shigellosis_Homo sapiens_hsa051310.72905821
75Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71566261
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.69914402
77Nicotine addiction_Homo sapiens_hsa050330.69667573
78Influenza A_Homo sapiens_hsa051640.61439818
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.61032985
80beta-Alanine metabolism_Homo sapiens_hsa004100.60530068
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60517426
82Sulfur relay system_Homo sapiens_hsa041220.59482135
83Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59371248
84Fatty acid degradation_Homo sapiens_hsa000710.59149906
85Galactose metabolism_Homo sapiens_hsa000520.58288756
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.58262152
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58138050
88Hepatitis B_Homo sapiens_hsa051610.57380959
89Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57140653
90Regulation of autophagy_Homo sapiens_hsa041400.56767777
91Jak-STAT signaling pathway_Homo sapiens_hsa046300.54752636
92Alzheimers disease_Homo sapiens_hsa050100.54709638
93Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.54698220
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54433602
95Allograft rejection_Homo sapiens_hsa053300.54022531
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53181612
97HTLV-I infection_Homo sapiens_hsa051660.52237829
98Thyroid cancer_Homo sapiens_hsa052160.51653223
99Hedgehog signaling pathway_Homo sapiens_hsa043400.51261108
100Fructose and mannose metabolism_Homo sapiens_hsa000510.50104260
101B cell receptor signaling pathway_Homo sapiens_hsa046620.49495905
102Systemic lupus erythematosus_Homo sapiens_hsa053220.49174784
103Type I diabetes mellitus_Homo sapiens_hsa049400.48354637
104Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.48198350
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47933680
106Viral carcinogenesis_Homo sapiens_hsa052030.46983628
107mRNA surveillance pathway_Homo sapiens_hsa030150.46936310
108Apoptosis_Homo sapiens_hsa042100.46383878
109Asthma_Homo sapiens_hsa053100.46365043
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45816901
1112-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45608441
112Hippo signaling pathway_Homo sapiens_hsa043900.44968125
113TGF-beta signaling pathway_Homo sapiens_hsa043500.44900930
114Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43839093
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.43738444
116Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43291040
117T cell receptor signaling pathway_Homo sapiens_hsa046600.43144989
118Circadian rhythm_Homo sapiens_hsa047100.41873945
119Collecting duct acid secretion_Homo sapiens_hsa049660.41721408
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40391258
121Carbon metabolism_Homo sapiens_hsa012000.40307182
122Acute myeloid leukemia_Homo sapiens_hsa052210.39633288
123Caffeine metabolism_Homo sapiens_hsa002320.39516644
124Basal cell carcinoma_Homo sapiens_hsa052170.38948317
125Glycosaminoglycan degradation_Homo sapiens_hsa005310.38938937
126Arginine and proline metabolism_Homo sapiens_hsa003300.38553040
127Metabolic pathways_Homo sapiens_hsa011000.36848219
128Malaria_Homo sapiens_hsa051440.36823365
129Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.34758520
130Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32963977
131Pertussis_Homo sapiens_hsa051330.32585218
132Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32213809
133Olfactory transduction_Homo sapiens_hsa047400.31335275
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30817597
135Alcoholism_Homo sapiens_hsa050340.29822806
136Taste transduction_Homo sapiens_hsa047420.29328074
137Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28296013
138GABAergic synapse_Homo sapiens_hsa047270.27057447
139Tight junction_Homo sapiens_hsa045300.26794136
140Primary bile acid biosynthesis_Homo sapiens_hsa001200.26683909
141Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.26610515
142Tuberculosis_Homo sapiens_hsa051520.24956428
143Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.24550123
144Arachidonic acid metabolism_Homo sapiens_hsa005900.24254391
145Osteoclast differentiation_Homo sapiens_hsa043800.23622600
146Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.23475626
147Hepatitis C_Homo sapiens_hsa051600.23409804
148Drug metabolism - other enzymes_Homo sapiens_hsa009830.23329687
149Vitamin digestion and absorption_Homo sapiens_hsa049770.22659582
150Vitamin B6 metabolism_Homo sapiens_hsa007500.22402790
151Chemical carcinogenesis_Homo sapiens_hsa052040.21603032

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