WEE2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1retinal cone cell development (GO:0046549)7.45550085
2regulation of acrosome reaction (GO:0060046)7.11319190
3positive regulation of histone H3-K4 methylation (GO:0051571)6.78701333
4regulation of histone H3-K9 methylation (GO:0051570)6.78104816
5mitotic metaphase plate congression (GO:0007080)6.54101267
6negative regulation of hormone biosynthetic process (GO:0032353)6.40303318
7negative regulation of hormone metabolic process (GO:0032351)6.40303318
8negative regulation of retinoic acid receptor signaling pathway (GO:0048387)6.34565053
9oocyte development (GO:0048599)6.33243962
10regulation of attachment of spindle microtubules to kinetochore (GO:0051988)6.29130619
11piRNA metabolic process (GO:0034587)6.08397547
12regulation of exit from mitosis (GO:0007096)5.83861309
13positive regulation of gastrulation (GO:2000543)5.83242148
14regulation of steroid hormone secretion (GO:2000831)5.82792977
15multicellular organism reproduction (GO:0032504)5.77752108
16female gamete generation (GO:0007292)5.73315404
17regulation of female gonad development (GO:2000194)5.58118977
18glycine transport (GO:0015816)5.56405643
19mitotic chromosome condensation (GO:0007076)5.32241671
20metaphase plate congression (GO:0051310)5.31964401
21DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla5.31441365
22DNA damage response, signal transduction resulting in transcription (GO:0042772)5.23512178
23primitive streak formation (GO:0090009)5.18652301
24oocyte maturation (GO:0001556)5.16947144
25negative regulation of meiosis (GO:0045835)5.16834820
26regulation of glucocorticoid metabolic process (GO:0031943)5.14129076
27regulation of RIG-I signaling pathway (GO:0039535)5.12274791
28regulation of histone H3-K27 methylation (GO:0061085)5.09682349
29monoubiquitinated protein deubiquitination (GO:0035520)5.07266676
30maturation of 5.8S rRNA (GO:0000460)5.01078701
31DNA damage induced protein phosphorylation (GO:0006975)5.00356608
32male meiosis (GO:0007140)4.95702705
33regulation of retinoic acid receptor signaling pathway (GO:0048385)4.94362869
34establishment of chromosome localization (GO:0051303)4.91854340
35glycerophospholipid catabolic process (GO:0046475)4.90634659
36* regulation of meiosis (GO:0040020)4.86561313
37mitotic sister chromatid segregation (GO:0000070)4.86343484
38meiotic chromosome segregation (GO:0045132)4.79652045
39positive regulation of megakaryocyte differentiation (GO:0045654)4.75973324
40synapsis (GO:0007129)4.72671797
41meiotic cell cycle (GO:0051321)4.70681570
42regulation of sister chromatid cohesion (GO:0007063)4.61074088
43type B pancreatic cell development (GO:0003323)4.56776698
44histone H2A monoubiquitination (GO:0035518)4.51073469
45positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.48180795
46protein kinase C signaling (GO:0070528)4.47154715
47chromosome organization involved in meiosis (GO:0070192)4.37123401
48regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)4.29881744
49positive regulation of histone methylation (GO:0031062)4.28333466
50female gonad development (GO:0008585)4.26774043
51regulation of transforming growth factor beta2 production (GO:0032909)4.23436172
52relaxation of smooth muscle (GO:0044557)4.21504107
53attachment of spindle microtubules to kinetochore (GO:0008608)4.20868281
54synaptonemal complex organization (GO:0070193)4.20681802
55oogenesis (GO:0048477)4.20643619
56protein K6-linked ubiquitination (GO:0085020)4.17097503
57positive regulation of humoral immune response (GO:0002922)4.04341327
58negative regulation of smooth muscle cell differentiation (GO:0051151)4.04330889
59neuron fate determination (GO:0048664)4.03904853
60positive regulation of DNA-dependent DNA replication (GO:2000105)3.97130838
61L-amino acid import (GO:0043092)3.96752331
62microtubule nucleation (GO:0007020)3.96560294
63myoblast migration (GO:0051451)3.95792311
64positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)3.92352233
65regulation of histone H3-K4 methylation (GO:0051569)3.92223937
66sister chromatid segregation (GO:0000819)3.91688712
67somite rostral/caudal axis specification (GO:0032525)3.91320208
68protein localization to chromosome, centromeric region (GO:0071459)3.90890614
69negative regulation of cAMP-mediated signaling (GO:0043951)3.90797957
70labyrinthine layer development (GO:0060711)3.88752805
71negative regulation of alcohol biosynthetic process (GO:1902931)3.88173264
72protein localization to chromosome (GO:0034502)3.85017165
73regulation of double-strand break repair via homologous recombination (GO:0010569)3.84174595
74protein localization to kinetochore (GO:0034501)3.83701375
75negative regulation of execution phase of apoptosis (GO:1900118)3.82967921
76centriole assembly (GO:0098534)3.82396856
77regulation of steroid hormone biosynthetic process (GO:0090030)3.81408718
78regulation of spindle organization (GO:0090224)3.80536662
79histone H2A ubiquitination (GO:0033522)3.80057096
80chromosome segregation (GO:0007059)3.79440236
81regulation of mononuclear cell migration (GO:0071675)3.77083385
82* regulation of meiotic cell cycle (GO:0051445)3.76624102
83DNA methylation involved in gamete generation (GO:0043046)3.75982434
84reproduction (GO:0000003)3.75018161
85phosphorelay signal transduction system (GO:0000160)3.74841760
86regulation of histone methylation (GO:0031060)3.70159507
87male meiosis I (GO:0007141)3.69557332
88meiosis I (GO:0007127)3.69493912
89regulation of spindle checkpoint (GO:0090231)3.65064282
90translesion synthesis (GO:0019985)3.63471364
91negative regulation of DNA-templated transcription, elongation (GO:0032785)3.62966107
92negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.62966107
93mitotic sister chromatid cohesion (GO:0007064)3.62833899
94fertilization (GO:0009566)3.62440899
95regulation of chromosome segregation (GO:0051983)3.60680272
96gene silencing (GO:0016458)3.59294187
97negative regulation of meiotic cell cycle (GO:0051447)3.52934522
98spindle checkpoint (GO:0031577)3.48684419
99positive regulation of chromosome segregation (GO:0051984)3.48440107
100regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.47688850
101phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.46965506
102snRNA transcription (GO:0009301)3.46792003
103regulation of mitotic spindle organization (GO:0060236)3.45197467
104microtubule severing (GO:0051013)3.44690065
105cytoplasmic mRNA processing body assembly (GO:0033962)3.43744486
106CENP-A containing nucleosome assembly (GO:0034080)3.43445690
107* negative regulation of reproductive process (GO:2000242)3.40297756
108sister chromatid cohesion (GO:0007062)3.39658861
109positive regulation of reproductive process (GO:2000243)3.39453264
110chromatin remodeling at centromere (GO:0031055)3.36040495
111parturition (GO:0007567)3.35795323
112pyrimidine-containing compound transmembrane transport (GO:0072531)3.35645529
113genitalia morphogenesis (GO:0035112)3.34658709
114dopamine biosynthetic process (GO:0042416)3.33811204
115negative regulation of histone modification (GO:0031057)3.31907491
116regulation of corticosteroid hormone secretion (GO:2000846)3.31104001
117regulation of chromatin silencing (GO:0031935)3.30375047
118gene silencing by RNA (GO:0031047)3.28909605
119DNA replication-independent nucleosome organization (GO:0034724)3.28760248
120DNA replication-independent nucleosome assembly (GO:0006336)3.28760248
121centrosome duplication (GO:0051298)3.27414622
122histone exchange (GO:0043486)3.25850995
123positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.24027207
124DNA replication-dependent nucleosome assembly (GO:0006335)3.23455541
125DNA replication-dependent nucleosome organization (GO:0034723)3.23455541
126citrulline biosynthetic process (GO:0019240)3.19321021
127notochord development (GO:0030903)3.18111370
128meiotic cell cycle process (GO:1903046)3.14797151
129glandular epithelial cell development (GO:0002068)3.14130644
130histone H3-K9 demethylation (GO:0033169)3.13737474
131mitotic nuclear envelope disassembly (GO:0007077)3.10121306
132centriole replication (GO:0007099)3.08668412
133negative regulation of cardiac muscle hypertrophy (GO:0010614)3.08420893
134synaptonemal complex assembly (GO:0007130)3.06316899
135negative regulation of cell division (GO:0051782)3.05421372
136positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.04889458
137positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.04889458
138positive regulation of mitotic sister chromatid separation (GO:1901970)3.04889458
139negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.03207688
140positive regulation of granulocyte differentiation (GO:0030854)3.02746220
141binding of sperm to zona pellucida (GO:0007339)3.02075624
142positive regulation of uterine smooth muscle contraction (GO:0070474)3.01696599
143N-terminal protein amino acid acetylation (GO:0006474)2.99772948
144positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862)2.99384017
145nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.98907477
146protein monoubiquitination (GO:0006513)2.98200136
147mitotic spindle checkpoint (GO:0071174)2.97506395
148DNA replication checkpoint (GO:0000076)2.97369877
149negative regulation of circadian rhythm (GO:0042754)2.97231565
150negative regulation of nuclear division (GO:0051784)2.97173239
151DNA methylation (GO:0006306)2.97057915
152DNA alkylation (GO:0006305)2.97057915
153negative regulation of histone methylation (GO:0031061)2.95621731
154positive regulation of meiosis (GO:0045836)2.94823784
155histone-serine phosphorylation (GO:0035404)2.94366542
156negative regulation of chromatin modification (GO:1903309)2.93515045
157regulation of G2/M transition of mitotic cell cycle (GO:0010389)2.92710539
158regulation of DNA methylation (GO:0044030)11.2341616

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse6.01457785
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.66569735
3SMAD_19615063_ChIP-ChIP_OVARY_Human4.58184291
4KAP1_22055183_ChIP-Seq_ESCs_Mouse4.13031048
5E2F7_22180533_ChIP-Seq_HELA_Human3.82340433
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.75337478
7KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.32939625
8KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.32939625
9KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.32939625
10AR_21909140_ChIP-Seq_LNCAP_Human3.16188538
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.04856833
12TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.96123888
13NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.92516408
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.90273952
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.89145192
16GATA1_26923725_Chip-Seq_HPCs_Mouse2.59244862
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.56169712
18RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.25619381
19IGF1R_20145208_ChIP-Seq_DFB_Human2.14469166
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.10041128
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.07082517
22EZH2_22144423_ChIP-Seq_EOC_Human13.1060058
23FLI1_27457419_Chip-Seq_LIVER_Mouse1.95138089
24SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.95037586
25LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.94648767
26GBX2_23144817_ChIP-Seq_PC3_Human1.91458054
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.90044597
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.88279764
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.79295541
30POU3F2_20337985_ChIP-ChIP_501MEL_Human1.76751093
31RUNX1_26923725_Chip-Seq_HPCs_Mouse1.74751066
32AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.73284978
33MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.69891434
34TP63_19390658_ChIP-ChIP_HaCaT_Human1.69627834
35MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.68685449
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62128337
37SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.57100211
38FUS_26573619_Chip-Seq_HEK293_Human1.56403065
39ESR1_20079471_ChIP-ChIP_T-47D_Human1.56117651
40CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54958619
41E2F1_21310950_ChIP-Seq_MCF-7_Human1.52999654
42TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.46000845
43KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.45038065
44PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.43234251
45E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42958758
46IRF1_19129219_ChIP-ChIP_H3396_Human1.41413897
47CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40167884
48RNF2_27304074_Chip-Seq_NSC_Mouse1.39819231
49POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39628768
50TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39628768
51ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.38322543
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.37927011
53BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.37715328
54MYC_18940864_ChIP-ChIP_HL60_Human1.37070542
55BP1_19119308_ChIP-ChIP_Hs578T_Human1.33443568
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32950142
57STAT1_17558387_ChIP-Seq_HELA_Human1.30359743
58HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.30293214
59STAT3_23295773_ChIP-Seq_U87_Human1.29722463
60KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.28719164
61CDX2_22108803_ChIP-Seq_LS180_Human1.27909571
62FOXM1_26456572_ChIP-Seq_MCF-7_Human1.26425693
63UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25577236
64CBP_20019798_ChIP-Seq_JUKART_Human1.23203719
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23203719
66CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.20900853
67TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.20755571
68SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19713170
69AUTS2_25519132_ChIP-Seq_293T-REX_Human1.18014935
70ELK4_26923725_Chip-Seq_MESODERM_Mouse1.14640293
71* TCF4_23295773_ChIP-Seq_U87_Human1.12827474
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09407151
73SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.09048010
74ERG_20517297_ChIP-Seq_VCAP_Human1.08184057
75CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07811901
76SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07428673
77HTT_18923047_ChIP-ChIP_STHdh_Human1.06644349
78NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.05839556
79AR_25329375_ChIP-Seq_VCAP_Human1.04897159
80SMAD4_21799915_ChIP-Seq_A2780_Human1.03516762
81CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.03298683
82NFYA_21822215_ChIP-Seq_K562_Human1.01043772
83EP300_21415370_ChIP-Seq_HL-1_Mouse1.00534904
84TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.99964717
85TBL1_22424771_ChIP-Seq_293T_Human0.99699366
86KAP1_27257070_Chip-Seq_ESCs_Mouse0.99550040
87NFE2_27457419_Chip-Seq_LIVER_Mouse0.98960115
88CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98486667
89RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.98092834
90RBPJ_22232070_ChIP-Seq_NCS_Mouse0.97869265
91NANOG_18555785_ChIP-Seq_MESCs_Mouse0.97868568
92GATA3_21867929_ChIP-Seq_TH1_Mouse0.97745991
93CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97203742
94KDM2B_26808549_Chip-Seq_REH_Human0.96992327
95GF1_26923725_Chip-Seq_HPCs_Mouse0.95680000
96SMAD4_21741376_ChIP-Seq_EPCs_Human0.95026686
97PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94889687
98CBP_21632823_ChIP-Seq_H3396_Human0.94428131
99LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94267866
100TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.94135339
101NANOG_20526341_ChIP-Seq_ESCs_Human0.94100333
102EWS_26573619_Chip-Seq_HEK293_Human0.93968411
103RUNX2_22187159_ChIP-Seq_PCA_Human0.93637525
104PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93495853
105STAT3_18555785_Chip-Seq_ESCs_Mouse0.93428622
106EZH2_27294783_Chip-Seq_NPCs_Mouse0.93056654
107SOX2_18555785_Chip-Seq_ESCs_Mouse0.92483712
108SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.91593449
109KLF4_18555785_Chip-Seq_ESCs_Mouse0.90392371
110AR_21572438_ChIP-Seq_LNCaP_Human0.89902166
111P300_19829295_ChIP-Seq_ESCs_Human0.89075394
112TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.88994393
113TAL1_26923725_Chip-Seq_HPCs_Mouse0.88605209
114TP53_16413492_ChIP-PET_HCT116_Human0.88442865
115EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.88342216
116PIAS1_25552417_ChIP-Seq_VCAP_Human0.88019112
117AHR_22903824_ChIP-Seq_MCF-7_Human0.87867432
118SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.87739137
119ZFP57_27257070_Chip-Seq_ESCs_Mouse0.87542900
120NMYC_18555785_Chip-Seq_ESCs_Mouse0.86505258
121EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.85898464
122MYCN_18555785_ChIP-Seq_MESCs_Mouse0.85871237
123EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.84897427
124NANOG_21062744_ChIP-ChIP_HESCs_Human0.84703849
125STAT3_18555785_ChIP-Seq_MESCs_Mouse0.84248280
126PRDM14_20953172_ChIP-Seq_ESCs_Human0.83924929
127CMYC_18555785_Chip-Seq_ESCs_Mouse0.83286476
128CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.82580950
129FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.82210600
130CTCF_18555785_Chip-Seq_ESCs_Mouse0.82148302
131SALL4_22934838_ChIP-ChIP_CD34+_Human0.81885668
132CTBP2_25329375_ChIP-Seq_LNCAP_Human0.81748055
133GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.81630023
134FOXH1_21741376_ChIP-Seq_EPCs_Human0.81567563
135NR3C1_23031785_ChIP-Seq_PC12_Mouse0.79353665
136PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.78891804
137PKCTHETA_26484144_Chip-Seq_BREAST_Human0.77555711
138SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.77426500
139SMRT_27268052_Chip-Seq_Bcells_Human0.76846120
140KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.75029589
141GATA1_19941827_ChIP-Seq_MEL86_Mouse0.73694989
142SMAD3_21741376_ChIP-Seq_EPCs_Human0.72518712
143ZNF217_24962896_ChIP-Seq_MCF-7_Human0.70491166
144ESR1_15608294_ChIP-ChIP_MCF-7_Human0.69241958
145ARNT_22903824_ChIP-Seq_MCF-7_Human0.67671317
146STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.67414573
147PADI4_21655091_ChIP-ChIP_MCF-7_Human0.65234597
148FOXO3_23340844_ChIP-Seq_DLD1_Human0.64922851
149TP53_22573176_ChIP-Seq_HFKS_Human0.64495665
150CREB1_15753290_ChIP-ChIP_HEK293T_Human0.64286976
151OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.63315301
152SOX2_21211035_ChIP-Seq_LN229_Gbm0.61425186
153GATA3_26560356_Chip-Seq_TH1_Human0.61369407
154KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.61155040
155KLF4_19829295_ChIP-Seq_ESCs_Human0.60700935
156TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.60370496
157NANOG_19829295_ChIP-Seq_ESCs_Human0.58239108

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002102_abnormal_ear_morphology5.78798904
2MP0005451_abnormal_body_composition5.60913078
3MP0003646_muscle_fatigue5.49254026
4MP0008789_abnormal_olfactory_epithelium4.93409711
5MP0003718_maternal_effect4.90034017
6MP0005394_taste/olfaction_phenotype4.29149696
7MP0005499_abnormal_olfactory_system4.29149696
8MP0002653_abnormal_ependyma_morphology4.21618519
9MP0003693_abnormal_embryo_hatching3.85650800
10MP0003890_abnormal_embryonic-extraembry3.31407537
11MP0002139_abnormal_hepatobiliary_system3.23956705
12MP0008877_abnormal_DNA_methylation3.19487286
13MP0003123_paternal_imprinting2.93934152
14MP0010094_abnormal_chromosome_stability2.75830602
15MP0002234_abnormal_pharynx_morphology2.69300462
16MP0002138_abnormal_hepatobiliary_system2.68111347
17MP0006292_abnormal_olfactory_placode2.65934378
18MP0003111_abnormal_nucleus_morphology2.64191918
19MP0003077_abnormal_cell_cycle2.56198961
20MP0001119_abnormal_female_reproductive2.51998991
21MP0005360_urolithiasis2.50277272
22MP0005408_hypopigmentation2.49412822
23MP0002249_abnormal_larynx_morphology2.44303857
24MP0003699_abnormal_female_reproductive2.42094958
25MP0005395_other_phenotype2.38929846
26MP0003787_abnormal_imprinting2.30045802
27MP0004957_abnormal_blastocyst_morpholog2.30033219
28MP0003183_abnormal_peptide_metabolism2.22930357
29MP0003879_abnormal_hair_cell2.18425368
30MP0001929_abnormal_gametogenesis2.04122294
31MP0000653_abnormal_sex_gland2.00243083
32MP0003121_genomic_imprinting1.95082996
33MP0005410_abnormal_fertilization1.84273699
34MP0000462_abnormal_digestive_system1.83720628
35MP0000579_abnormal_nail_morphology1.82515348
36MP0002210_abnormal_sex_determination1.79418765
37MP0003937_abnormal_limbs/digits/tail_de1.78180691
38MP0004185_abnormal_adipocyte_glucose1.74548896
39MP0001529_abnormal_vocalization1.54269565
40MP0002160_abnormal_reproductive_system1.48249889
41MP0001984_abnormal_olfaction1.45596794
42MP0001293_anophthalmia1.44597741
43MP0005310_abnormal_salivary_gland1.39905747
44MP0010234_abnormal_vibrissa_follicle1.39792486
45MP0001145_abnormal_male_reproductive1.38074845
46MP0010368_abnormal_lymphatic_system1.38026254
47MP0001915_intracranial_hemorrhage1.36141298
48MP0008007_abnormal_cellular_replicative1.35188573
49MP0002085_abnormal_embryonic_tissue1.34860321
50MP0005646_abnormal_pituitary_gland1.34811982
51MP0002877_abnormal_melanocyte_morpholog1.33937405
52MP0008932_abnormal_embryonic_tissue1.33481212
53MP0000762_abnormal_tongue_morphology1.32552229
54MP0002161_abnormal_fertility/fecundity1.28358549
55MP0004264_abnormal_extraembryonic_tissu1.25862058
56MP0000639_abnormal_adrenal_gland1.24186698
57MP0001697_abnormal_embryo_size1.22957057
58MP0001730_embryonic_growth_arrest1.19921941
59MP0003252_abnormal_bile_duct1.18474231
60MP0001851_eye_inflammation1.17646414
61MP0000350_abnormal_cell_proliferation1.16228005
62MP0002084_abnormal_developmental_patter1.16070787
63MP0001905_abnormal_dopamine_level1.10573746
64MP0000566_synostosis1.07545454
65MP0001346_abnormal_lacrimal_gland1.04728062
66MP0009840_abnormal_foam_cell1.01240389
67MP0001672_abnormal_embryogenesis/_devel0.97488965
68MP0005380_embryogenesis_phenotype0.97488965
69MP0003315_abnormal_perineum_morphology0.96592734
70MP0009250_abnormal_appendicular_skeleto0.96456129
71MP0003656_abnormal_erythrocyte_physiolo0.94849692
72MP0003119_abnormal_digestive_system0.94473311
73MP0003755_abnormal_palate_morphology0.94270159
74MP0010678_abnormal_skin_adnexa0.90750182
75MP0003698_abnormal_male_reproductive0.84001566
76MP0005085_abnormal_gallbladder_physiolo0.83954752
77MP0010386_abnormal_urinary_bladder0.83582158
78MP0004270_analgesia0.82494119
79MP0004142_abnormal_muscle_tone0.82324666
80MP0002272_abnormal_nervous_system0.82277887
81MP0001986_abnormal_taste_sensitivity0.81534035
82MP0004510_myositis0.80985129
83MP0002019_abnormal_tumor_incidence0.79620756
84MP0001849_ear_inflammation0.76913972
85MP0002177_abnormal_outer_ear0.75905303
86MP0000049_abnormal_middle_ear0.74626965
87MP0010030_abnormal_orbit_morphology0.74240376
88MP0001666_abnormal_nutrient_absorption0.74022650
89MP0005551_abnormal_eye_electrophysiolog0.73524386
90MP0002796_impaired_skin_barrier0.72814768
91MP0002233_abnormal_nose_morphology0.72633731
92MP0001324_abnormal_eye_pigmentation0.72575347
93MP0006276_abnormal_autonomic_nervous0.72144182
94MP0002116_abnormal_craniofacial_bone0.71342295
95MP0004145_abnormal_muscle_electrophysio0.69923882
96MP0003136_yellow_coat_color0.69755523
97MP0000490_abnormal_crypts_of0.69534690
98MP0003868_abnormal_feces_composition0.69240096
99MP0010307_abnormal_tumor_latency0.68935702
100MP0005248_abnormal_Harderian_gland0.68621997
101MP0003984_embryonic_growth_retardation0.68509666
102MP0001664_abnormal_digestion0.67318580
103MP0005187_abnormal_penis_morphology0.67179784
104MP0002168_other_aberrant_phenotype0.67157735
105MP0005647_abnormal_sex_gland0.66951767
106MP0000432_abnormal_head_morphology0.65847910
107MP0000427_abnormal_hair_cycle0.65602118
108MP0005621_abnormal_cell_physiology0.63830964
109MP0002088_abnormal_embryonic_growth/wei0.63498686
110MP0008058_abnormal_DNA_repair0.62909768
111MP0003861_abnormal_nervous_system0.62849442
112MP0000678_abnormal_parathyroid_gland0.61971331
113MP0002086_abnormal_extraembryonic_tissu0.61734265
114MP0000631_abnormal_neuroendocrine_gland0.61307532
115MP0003329_amyloid_beta_deposits0.59596836
116MP0003453_abnormal_keratinocyte_physiol0.58397777
117MP0003935_abnormal_craniofacial_develop0.57082437
118MP0000613_abnormal_salivary_gland0.56490188
119MP0001919_abnormal_reproductive_system0.56091875
120MP0008057_abnormal_DNA_replication0.55468097
121MP0005501_abnormal_skin_physiology0.55114298
122MP0002080_prenatal_lethality0.55000988
123MP0002396_abnormal_hematopoietic_system0.54657893
124MP0005197_abnormal_uvea_morphology0.54546115
125MP0003941_abnormal_skin_development0.54316437
126MP0001502_abnormal_circadian_rhythm0.54285842
127MP0002638_abnormal_pupillary_reflex0.53897406
128MP0003632_abnormal_nervous_system0.53552357
129MP0005389_reproductive_system_phenotype0.53389518
130MP0004043_abnormal_pH_regulation0.53070934
131MP0005075_abnormal_melanosome_morpholog0.52495483
132MP0003950_abnormal_plasma_membrane0.52402629
133MP0002109_abnormal_limb_morphology0.52380060
134MP0000534_abnormal_ureter_morphology0.51903681
135MP0002163_abnormal_gland_morphology0.49437128
136MP0005508_abnormal_skeleton_morphology0.48087473
137MP0002090_abnormal_vision0.47575243
138MP0003938_abnormal_ear_development0.47222452
139MP0001963_abnormal_hearing_physiology0.47121219
140MP0000428_abnormal_craniofacial_morphol0.45649412
141MP0002751_abnormal_autonomic_nervous0.45219805
142MP0002928_abnormal_bile_duct0.44512457
143MP0000015_abnormal_ear_pigmentation0.43736604
144MP0002127_abnormal_cardiovascular_syste0.42744319
145MP0002089_abnormal_postnatal_growth/wei0.40483173
146MP0000377_abnormal_hair_follicle0.39642550
147MP0005503_abnormal_tendon_morphology0.38354991
148MP0004381_abnormal_hair_follicle0.36650035
149MP0006138_congestive_heart_failure0.33269997
150MP0002873_normal_phenotype0.32791835
151MP0009379_abnormal_foot_pigmentation0.32604599
152MP0002169_no_abnormal_phenotype0.32280493
153MP0000026_abnormal_inner_ear0.31261167

Predicted human phenotypes

RankGene SetZ-score
1Male infertility (HP:0003251)6.83446670
2Abnormality of abdominal situs (HP:0011620)5.48186076
3Abdominal situs inversus (HP:0003363)5.48186076
4Papillary thyroid carcinoma (HP:0002895)5.42717161
5Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)5.19602233
6Facial hemangioma (HP:0000329)5.01391978
7Cholecystitis (HP:0001082)4.86031388
8Abnormal gallbladder physiology (HP:0012438)4.86031388
9Septo-optic dysplasia (HP:0100842)4.72666393
10Osteomalacia (HP:0002749)4.67877206
11Shawl scrotum (HP:0000049)4.58504996
12Birth length less than 3rd percentile (HP:0003561)4.44639058
13Chromsome breakage (HP:0040012)4.40677823
14Adrenal hypoplasia (HP:0000835)4.30340362
15Impulsivity (HP:0100710)4.28880075
16Capillary hemangiomas (HP:0005306)4.13134177
17Breast hypoplasia (HP:0003187)4.12902203
18Patellar aplasia (HP:0006443)4.12761272
19Chromosomal breakage induced by crosslinking agents (HP:0003221)4.06927757
20Flat capital femoral epiphysis (HP:0003370)4.06723840
21Hypophosphatemic rickets (HP:0004912)4.05804630
22Azoospermia (HP:0000027)3.91026263
23Absent septum pellucidum (HP:0001331)3.90445562
24Abnormality of the labia minora (HP:0012880)3.89138479
25Median cleft lip (HP:0000161)3.88329049
26Abnormality of the fingertips (HP:0001211)3.81450740
27Aplasia/Hypoplasia of the patella (HP:0006498)3.81180988
28Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.64852252
29Short tibia (HP:0005736)3.56518154
30Gonadotropin excess (HP:0000837)3.50545603
31Acute myeloid leukemia (HP:0004808)3.37287290
32Malnutrition (HP:0004395)3.36622767
33Arterial tortuosity (HP:0005116)3.34284012
34Abnormality of the septum pellucidum (HP:0007375)3.33983190
35Secondary amenorrhea (HP:0000869)3.27120713
36Breast aplasia (HP:0100783)3.26487456
37Abnormality of lateral ventricle (HP:0030047)3.23363481
38Lip pit (HP:0100267)3.22321788
39Aplasia/Hypoplasia of the breasts (HP:0010311)3.21408743
40Aplasia/Hypoplasia of the tibia (HP:0005772)3.16818355
41Cortical dysplasia (HP:0002539)3.16561053
42Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.08195449
43Fair hair (HP:0002286)3.07039053
44Hypokinesia (HP:0002375)2.98578902
45Abnormal spermatogenesis (HP:0008669)2.98330184
46Abnormality of chromosome segregation (HP:0002916)2.98006142
47Apathy (HP:0000741)2.97319607
48Spondylolisthesis (HP:0003302)2.95611873
49Thyroid carcinoma (HP:0002890)2.94374148
50Diminished motivation (HP:0000745)2.89070860
51Vascular tortuosity (HP:0004948)2.87312197
52Stillbirth (HP:0003826)2.85887308
53Oligodactyly (hands) (HP:0001180)2.83873797
54Sandal gap (HP:0001852)2.82068959
55Oligodactyly (HP:0012165)2.80161969
56Premature ovarian failure (HP:0008209)2.77442517
57Pulmonary fibrosis (HP:0002206)2.76308651
58Ankle contracture (HP:0006466)2.68953701
59Chronic bronchitis (HP:0004469)2.65976238
60Hypergonadotropic hypogonadism (HP:0000815)2.65367553
61Aplasia/Hypoplasia of the macula (HP:0008059)2.64016146
62Abnormality of chromosome stability (HP:0003220)2.62686427
63Maternal diabetes (HP:0009800)2.60236391
64Infertility (HP:0000789)2.58200969
65Abnormality of the fovea (HP:0000493)2.57630355
66Prostate neoplasm (HP:0100787)2.57101152
67Urethral obstruction (HP:0000796)2.53872244
68Conjunctival telangiectasia (HP:0000524)2.53567572
69Rib fusion (HP:0000902)2.50066721
70Microglossia (HP:0000171)2.49345690
71Abnormality of the phalanges of the hallux (HP:0010057)2.49255506
72Cystic hygroma (HP:0000476)2.47837538
73Lower limb hyperreflexia (HP:0002395)2.47828563
74Truncal obesity (HP:0001956)2.47369193
75Sparse lateral eyebrow (HP:0005338)2.46896784
76Spinal cord compression (HP:0002176)2.46355238
77Aplasia/Hypoplasia of the fovea (HP:0008060)2.46294713
78Hypoplasia of the fovea (HP:0007750)2.46294713
79Metaphyseal irregularity (HP:0003025)2.43945638
80Supernumerary spleens (HP:0009799)2.43524251
81Aplasia/Hypoplasia of the uvula (HP:0010293)2.42344884
82Aplasia/Hypoplasia affecting the retina (HP:0008061)2.40908282
83Intrahepatic cholestasis (HP:0001406)2.38484419
84Overlapping toe (HP:0001845)2.37653247
85Primary amenorrhea (HP:0000786)2.35840121
86Abnormal ciliary motility (HP:0012262)2.33318078
87Anterior segment dysgenesis (HP:0007700)2.33144441
88Muscle stiffness (HP:0003552)2.28293606
89Abnormality of the preputium (HP:0100587)2.28263964
90Pancreatic fibrosis (HP:0100732)2.27897809
91Insulin-resistant diabetes mellitus (HP:0000831)2.27233520
92Posterior subcapsular cataract (HP:0007787)2.26056931
93Sensory axonal neuropathy (HP:0003390)2.23954897
94Ectopic kidney (HP:0000086)2.23952721
95Proximal tubulopathy (HP:0000114)2.23119631
96Wrist flexion contracture (HP:0001239)2.22878800
97Carpal bone hypoplasia (HP:0001498)2.22619538
98Skin pits (HP:0100276)2.20928693
99Dysdiadochokinesis (HP:0002075)2.20710901
100Abnormal biliary tract physiology (HP:0012439)2.20703253
101Bile duct proliferation (HP:0001408)2.20703253
102Abnormality of the epiphysis of the femoral head (HP:0010574)2.20461868
103Meckel diverticulum (HP:0002245)2.20178978
104Generalized hypopigmentation of hair (HP:0011358)2.19771181
105Nonprogressive disorder (HP:0003680)2.19728790
106Heterotopia (HP:0002282)2.19681783
107Nephroblastoma (Wilms tumor) (HP:0002667)2.17574351
108Hip contracture (HP:0003273)2.16906912
109Striae distensae (HP:0001065)2.16055377
110Midline defect of the nose (HP:0004122)2.13913875
111Congenital sensorineural hearing impairment (HP:0008527)2.13306009
112Abnormal lung lobation (HP:0002101)2.13232694
113Aplasia of the musculature (HP:0100854)2.12587648
114Aplasia/Hypoplasia of the sternum (HP:0006714)2.11628680
115Aplasia/Hypoplasia affecting the fundus (HP:0008057)2.11359477
116Hypoplastic iliac wings (HP:0002866)2.10092982
117Camptodactyly of toe (HP:0001836)2.09981783
118Shallow orbits (HP:0000586)2.09686606
119Bicornuate uterus (HP:0000813)2.07338602
120Embryonal renal neoplasm (HP:0011794)2.05063508
121Anhidrosis (HP:0000970)2.05024044
122Absent radius (HP:0003974)2.04852819
123Abnormality of the ileum (HP:0001549)2.03854167
124Bundle branch block (HP:0011710)2.03599174
125Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.03361894
126Abnormality of the femoral head (HP:0003368)2.03142998
127Myelodysplasia (HP:0002863)2.02839911
128Generalized aminoaciduria (HP:0002909)2.01783632
129Hyperglycemia (HP:0003074)2.01425037
130Type 2 muscle fiber atrophy (HP:0003554)2.00130188
131Clubbing of toes (HP:0100760)1.98956943
132Loss of speech (HP:0002371)1.98700383
133Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.98311522
134Abnormality of femoral epiphyses (HP:0006499)1.98311522
135Abnormality of the vasculature of the conjunctiva (HP:0008054)1.95931984
136Aplasia involving forearm bones (HP:0009822)1.95926989
137Absent forearm bone (HP:0003953)1.95926989
138Limb hypertonia (HP:0002509)1.95872895
139Abnormality of aromatic amino acid family metabolism (HP:0004338)1.95338407
140Optic nerve hypoplasia (HP:0000609)1.95216258
141Muscle fiber atrophy (HP:0100295)1.90762700
142Myokymia (HP:0002411)1.90148467
143Duodenal stenosis (HP:0100867)1.89830394
144Small intestinal stenosis (HP:0012848)1.89830394
145Short thumb (HP:0009778)1.87409416
146Spontaneous abortion (HP:0005268)1.86843004
147Optic neuritis (HP:0100653)1.85791521
148Retrobulbar optic neuritis (HP:0100654)1.85791521
149Sloping forehead (HP:0000340)1.84417368
150Aplastic anemia (HP:0001915)1.82152556
151Pancreatic cysts (HP:0001737)1.81676028
152Fibular aplasia (HP:0002990)1.80503005
153Cafe-au-lait spot (HP:0000957)1.80169943
154Hypohidrosis (HP:0000966)1.79620977
155Aplasia/Hypoplasia involving the musculature (HP:0001460)1.78635753
156Abnormality of the labia (HP:0000058)1.78484778
157Abnormal respiratory motile cilium physiology (HP:0012261)1.76751016
158Tetany (HP:0001281)1.76633020
159Abnormality of the proximal phalanges of the hand (HP:0009834)1.75904216
160Fetal akinesia sequence (HP:0001989)1.75292467
161Pendular nystagmus (HP:0012043)1.74330940
162Enlarged penis (HP:0000040)1.72949066
163Aplasia/Hypoplasia of the tongue (HP:0010295)1.71140244
164Chin dimple (HP:0010751)1.69090265
165Decreased muscle mass (HP:0003199)1.66733703
166Erectile abnormalities (HP:0100639)1.65712530
167Abnormality of small intestinal villus morphology (HP:0011472)1.65411148

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS13.93830197
2KSR23.82902231
3MUSK3.77897258
4MAP3K63.73321929
5LATS23.69443601
6EEF2K3.51369367
7PLK43.46838928
8ERBB43.40177258
9NEK63.20958722
10MAP3K93.13726231
11BRAF3.03354833
12STK38L2.84649078
13TAOK12.81497867
14TAOK32.81258979
15MAP3K132.73693634
16RAF12.69406289
17TTK2.56127300
18ARAF2.39620451
19MET2.33072450
20MAPKAPK32.31782267
21CDC72.22066837
22MOS1.93662880
23KSR11.75523875
24EIF2AK31.73897268
25PAK61.69027165
26CDK81.61588280
27STK31.56421696
28CDK91.48154419
29MELK1.45941870
30NEK21.33381035
31CHEK21.32794202
32PRKD31.32674544
33MAPKAPK51.32247592
34MAPK131.25346349
35TNIK1.25230717
36DYRK21.20510957
37TRIM281.10563485
38PRKD21.02265269
39PLK11.01670008
40DMPK1.01519531
41MST40.99399013
42MAP3K40.99076868
43TRPM70.96685663
44ZAK0.95359366
45TIE10.95158942
46ABL20.94646647
47PIM10.92186038
48MARK20.91288717
49BMPR20.85132782
50STK390.82505311
51PRKAA20.82051134
52TYRO30.81905279
53NUAK10.80791258
54STK380.78571177
55RPS6KB20.76084811
56STK100.75693142
57ACVR1B0.75552504
58MARK30.75448311
59MAP3K80.74868677
60TNK20.67738343
61MAP2K70.64076525
62AURKB0.63061109
63WNK10.59941108
64PRKAA10.59650818
65MAP2K40.57710313
66CSNK1D0.56832867
67MAP3K50.56337216
68RET0.55888033
69PRKG10.55657129
70PLK30.54920078
71TGFBR10.53949522
72CDK30.53221792
73STK240.52666858
74NTRK20.51790054
75BRSK10.51758898
76CSNK1G10.49626517
77PTK20.49434565
78AURKA0.48782112
79MAP3K10.47865010
80MAPK110.47582578
81EPHA30.45355536
82NTRK30.44562468
83CDK190.43873424
84ATR0.43494967
85CHEK10.42164648
86ATM0.41174334
87CHUK0.40468238
88CSNK1G20.40007093
89NEK90.39978279
90JAK30.39907206
91PRKCZ0.39671645
92NLK0.39194837
93SGK20.37651905
94PKN10.37068068
95MTOR0.36788753
96CSNK1E0.35482150
97BRSK20.33012412
98LRRK20.31775257
99CSNK1G30.31585711
100CDK120.31394771
101CDK50.31354102
102BUB10.30659604
103HIPK20.30560235
104MAP2K10.29251641
105PRKACB0.28708483
106PINK10.26963630
107VRK10.26458043
108RPS6KA40.25566473
109MAPK10.25546761
110PAK30.25113599
111CDK70.24423027
112ABL10.24413608
113OXSR10.23900912
114JAK20.23516651
115SRPK10.23497754
116FGR0.23425056
117PDK10.23109826
118CDK10.22506852
119CDK150.21961886
120CDK20.21582838
121GSK3B0.21467900
122SGK2230.20419748
123SGK4940.20419748
124MAP3K120.20003750
125BMPR1B0.19357182
126CDK180.19332241
127CDK40.18446858
128CSNK1A1L0.17973653
129* PRKACA0.17284564
130PBK0.17195630
131MAPK100.16125485
132CDK11A0.16095817
133LMTK20.15796667
134PAK10.15140071
135EGFR0.15088521
136AKT20.13255475
137PRKCI0.12477774
138EIF2AK20.10320072
139TLK10.07260404
140PDPK10.07225772
141BRD40.06704872

Predicted pathways (KEGG)

RankGene SetZ-score
1* Cell cycle_Homo sapiens_hsa041103.83476962
2RNA degradation_Homo sapiens_hsa030183.65676828
3Ovarian steroidogenesis_Homo sapiens_hsa049133.54423300
4Caffeine metabolism_Homo sapiens_hsa002323.48073672
5Circadian rhythm_Homo sapiens_hsa047103.15338632
6Basal transcription factors_Homo sapiens_hsa030223.07210114
7Vitamin B6 metabolism_Homo sapiens_hsa007503.00053199
8Pancreatic cancer_Homo sapiens_hsa052122.54728222
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.46496622
10Linoleic acid metabolism_Homo sapiens_hsa005912.41094196
11Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.32298585
12TGF-beta signaling pathway_Homo sapiens_hsa043502.31223926
13Ether lipid metabolism_Homo sapiens_hsa005652.15286545
14Oocyte meiosis_Homo sapiens_hsa041142.11092241
15Olfactory transduction_Homo sapiens_hsa047402.06137236
16Homologous recombination_Homo sapiens_hsa034401.95415009
17p53 signaling pathway_Homo sapiens_hsa041151.90358005
18Folate biosynthesis_Homo sapiens_hsa007901.75273441
19GnRH signaling pathway_Homo sapiens_hsa049121.75059068
20Prolactin signaling pathway_Homo sapiens_hsa049171.72933339
21Fanconi anemia pathway_Homo sapiens_hsa034601.70143047
22Choline metabolism in cancer_Homo sapiens_hsa052311.67347940
23Dorso-ventral axis formation_Homo sapiens_hsa043201.64798033
24RNA polymerase_Homo sapiens_hsa030201.63593196
25Colorectal cancer_Homo sapiens_hsa052101.60849459
26Gap junction_Homo sapiens_hsa045401.51180038
27Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.49895495
28MicroRNAs in cancer_Homo sapiens_hsa052061.39210668
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.38678362
30Renal cell carcinoma_Homo sapiens_hsa052111.38449387
31RNA transport_Homo sapiens_hsa030131.30936416
32Phototransduction_Homo sapiens_hsa047441.29685240
33VEGF signaling pathway_Homo sapiens_hsa043701.28046678
34Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.24533933
35Base excision repair_Homo sapiens_hsa034101.13633216
36Endometrial cancer_Homo sapiens_hsa052131.11771446
37Adherens junction_Homo sapiens_hsa045201.08220042
38Mismatch repair_Homo sapiens_hsa034301.05348668
39SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03148239
40Nicotine addiction_Homo sapiens_hsa050331.01745011
41FoxO signaling pathway_Homo sapiens_hsa040681.01667113
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00776264
43Long-term depression_Homo sapiens_hsa047301.00767753
44ABC transporters_Homo sapiens_hsa020101.00616398
45Thyroid cancer_Homo sapiens_hsa052160.99237919
46Hippo signaling pathway_Homo sapiens_hsa043900.98378403
47Other glycan degradation_Homo sapiens_hsa005110.98065969
48Nucleotide excision repair_Homo sapiens_hsa034200.96707490
49Non-homologous end-joining_Homo sapiens_hsa034500.95992454
50Non-small cell lung cancer_Homo sapiens_hsa052230.93447526
51Glycerophospholipid metabolism_Homo sapiens_hsa005640.90600906
52Small cell lung cancer_Homo sapiens_hsa052220.90571411
53Synaptic vesicle cycle_Homo sapiens_hsa047210.88420890
54DNA replication_Homo sapiens_hsa030300.87967337
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.86446008
56Hepatitis B_Homo sapiens_hsa051610.85750058
57Phospholipase D signaling pathway_Homo sapiens_hsa040720.85525588
58Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84923743
59Bile secretion_Homo sapiens_hsa049760.84524658
60Morphine addiction_Homo sapiens_hsa050320.83970543
61Ras signaling pathway_Homo sapiens_hsa040140.83909402
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.83366915
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81756101
64Chronic myeloid leukemia_Homo sapiens_hsa052200.81493779
65Bladder cancer_Homo sapiens_hsa052190.80951917
66Prostate cancer_Homo sapiens_hsa052150.79645125
67GABAergic synapse_Homo sapiens_hsa047270.75214158
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.74007788
69mRNA surveillance pathway_Homo sapiens_hsa030150.73685402
70mTOR signaling pathway_Homo sapiens_hsa041500.72691907
71Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.72320771
72Estrogen signaling pathway_Homo sapiens_hsa049150.70733604
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69716330
74ErbB signaling pathway_Homo sapiens_hsa040120.69300196
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68594976
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68199325
77Vitamin digestion and absorption_Homo sapiens_hsa049770.65590905
78Notch signaling pathway_Homo sapiens_hsa043300.65287713
79Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.62656297
80Fatty acid elongation_Homo sapiens_hsa000620.62603957
81Arachidonic acid metabolism_Homo sapiens_hsa005900.61300336
82Glioma_Homo sapiens_hsa052140.59095262
83Inositol phosphate metabolism_Homo sapiens_hsa005620.58672717
84Herpes simplex infection_Homo sapiens_hsa051680.56553770
85Serotonergic synapse_Homo sapiens_hsa047260.53490447
86MAPK signaling pathway_Homo sapiens_hsa040100.53241611
87Taste transduction_Homo sapiens_hsa047420.49928291
88Pyrimidine metabolism_Homo sapiens_hsa002400.48690063
89Purine metabolism_Homo sapiens_hsa002300.48488970
90Melanoma_Homo sapiens_hsa052180.47465588
91HTLV-I infection_Homo sapiens_hsa051660.46716068
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.43956795
93TNF signaling pathway_Homo sapiens_hsa046680.43899261
94Vascular smooth muscle contraction_Homo sapiens_hsa042700.42926228
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.42865349
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.42551504
97cAMP signaling pathway_Homo sapiens_hsa040240.41849682
98Shigellosis_Homo sapiens_hsa051310.36952573
99AMPK signaling pathway_Homo sapiens_hsa041520.35931442
100Glutamatergic synapse_Homo sapiens_hsa047240.34839381
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34025509
102Wnt signaling pathway_Homo sapiens_hsa043100.33275234
103Pathways in cancer_Homo sapiens_hsa052000.32514092
104cGMP-PKG signaling pathway_Homo sapiens_hsa040220.32243243
105Jak-STAT signaling pathway_Homo sapiens_hsa046300.32005783
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.31460644
107Lysine degradation_Homo sapiens_hsa003100.31173656
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29894779
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.27568879
110Aldosterone synthesis and secretion_Homo sapiens_hsa049250.26327160
111Cocaine addiction_Homo sapiens_hsa050300.25890055
112Hedgehog signaling pathway_Homo sapiens_hsa043400.25009686
113Epstein-Barr virus infection_Homo sapiens_hsa051690.24624298
114Sphingolipid metabolism_Homo sapiens_hsa006000.24423529
115Arginine and proline metabolism_Homo sapiens_hsa003300.24418792
116Regulation of autophagy_Homo sapiens_hsa041400.24238687
117Glycosaminoglycan degradation_Homo sapiens_hsa005310.23958162
118Oxytocin signaling pathway_Homo sapiens_hsa049210.23698628
119Viral carcinogenesis_Homo sapiens_hsa052030.23201235
120Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.21885806
121Rap1 signaling pathway_Homo sapiens_hsa040150.21081401
122Phagosome_Homo sapiens_hsa041450.20620442
123Maturity onset diabetes of the young_Homo sapiens_hsa049500.20540232
124Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.20402998
125Tight junction_Homo sapiens_hsa045300.19663444
126Protein digestion and absorption_Homo sapiens_hsa049740.14389479
127Cholinergic synapse_Homo sapiens_hsa047250.13248328
128Propanoate metabolism_Homo sapiens_hsa006400.12606118
129Long-term potentiation_Homo sapiens_hsa047200.11926613
130Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.10665624
131Spliceosome_Homo sapiens_hsa030400.07894147
132Circadian entrainment_Homo sapiens_hsa047130.07444255
133Neurotrophin signaling pathway_Homo sapiens_hsa047220.06772708
134Arginine biosynthesis_Homo sapiens_hsa002200.05526964
135PI3K-Akt signaling pathway_Homo sapiens_hsa041510.05043413
136Drug metabolism - other enzymes_Homo sapiens_hsa009830.04875111

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »