

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | thrombin receptor signaling pathway (GO:0070493) | 6.05206299 |
| 2 | protein neddylation (GO:0045116) | 5.75661854 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 4.64581641 |
| 4 | regulation of platelet aggregation (GO:0090330) | 4.21312134 |
| 5 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 4.00941420 |
| 6 | regulation of platelet activation (GO:0010543) | 3.96652260 |
| 7 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.83561679 |
| 8 | negative regulation of heart rate (GO:0010459) | 3.74705226 |
| 9 | regulation of memory T cell differentiation (GO:0043380) | 3.71672580 |
| 10 | blood coagulation, intrinsic pathway (GO:0007597) | 3.67540356 |
| 11 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.59510453 |
| 12 | cellular biogenic amine catabolic process (GO:0042402) | 3.57057899 |
| 13 | amine catabolic process (GO:0009310) | 3.57057899 |
| 14 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.56662874 |
| 15 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.54740954 |
| 16 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 3.51844000 |
| 17 | positive regulation of mast cell activation (GO:0033005) | 3.44972800 |
| 18 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.44317636 |
| 19 | dopamine transport (GO:0015872) | 3.40122229 |
| 20 | negative regulation of neurotransmitter transport (GO:0051589) | 3.39508644 |
| 21 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.35098854 |
| 22 | regulation of integrin-mediated signaling pathway (GO:2001044) | 3.34647998 |
| 23 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.34579490 |
| 24 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.33775791 |
| 25 | platelet dense granule organization (GO:0060155) | 3.32401935 |
| 26 | neutrophil activation (GO:0042119) | 3.29014373 |
| 27 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.25677831 |
| 28 | negative regulation of appetite (GO:0032099) | 3.25443646 |
| 29 | negative regulation of response to food (GO:0032096) | 3.25443646 |
| 30 | indolalkylamine metabolic process (GO:0006586) | 3.22278003 |
| 31 | negative regulation of protein localization to cell surface (GO:2000009) | 3.21879626 |
| 32 | positive regulation of granulocyte differentiation (GO:0030854) | 3.19710230 |
| 33 | negative regulation of norepinephrine secretion (GO:0010700) | 3.16886429 |
| 34 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.15078748 |
| 35 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 3.12682633 |
| 36 | tachykinin receptor signaling pathway (GO:0007217) | 3.03407501 |
| 37 | indole-containing compound catabolic process (GO:0042436) | 3.03231716 |
| 38 | indolalkylamine catabolic process (GO:0046218) | 3.03231716 |
| 39 | tryptophan catabolic process (GO:0006569) | 3.03231716 |
| 40 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.02329808 |
| 41 | negative regulation of platelet activation (GO:0010544) | 3.00811149 |
| 42 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.99352717 |
| 43 | adenosine metabolic process (GO:0046085) | 2.98225686 |
| 44 | regulation of lipoprotein metabolic process (GO:0050746) | 2.97455647 |
| 45 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.96669698 |
| 46 | termination of signal transduction (GO:0023021) | 2.89357027 |
| 47 | purinergic receptor signaling pathway (GO:0035587) | 2.82518455 |
| 48 | autophagic vacuole fusion (GO:0000046) | 2.82131680 |
| 49 | megakaryocyte development (GO:0035855) | 2.80055169 |
| 50 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.79848062 |
| 51 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.79848062 |
| 52 | regulation of female receptivity (GO:0045924) | 2.79818834 |
| 53 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.79584176 |
| 54 | phospholipid homeostasis (GO:0055091) | 2.78375218 |
| 55 | regulation of mast cell activation (GO:0033003) | 2.78008877 |
| 56 | low-density lipoprotein particle remodeling (GO:0034374) | 2.76583647 |
| 57 | platelet aggregation (GO:0070527) | 2.75298950 |
| 58 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 2.71044115 |
| 59 | granulocyte activation (GO:0036230) | 2.68928643 |
| 60 | negative regulation of mast cell activation (GO:0033004) | 2.66297179 |
| 61 | monoamine transport (GO:0015844) | 2.62835573 |
| 62 | neural tube formation (GO:0001841) | 2.62231161 |
| 63 | adenosine receptor signaling pathway (GO:0001973) | 2.60281949 |
| 64 | regulation of endothelial cell differentiation (GO:0045601) | 2.59300002 |
| 65 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2.58915473 |
| 66 | negative regulation of G-protein coupled receptor protein signaling pathway (GO:0045744) | 2.57168295 |
| 67 | angiogenesis involved in wound healing (GO:0060055) | 2.55375608 |
| 68 | organelle membrane fusion (GO:0090174) | 2.53182350 |
| 69 | adaptation of signaling pathway (GO:0023058) | 2.52871115 |
| 70 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.52245636 |
| 71 | aromatic amino acid family catabolic process (GO:0009074) | 2.52124625 |
| 72 | cardiolipin metabolic process (GO:0032048) | 2.51726094 |
| 73 | tryptophan metabolic process (GO:0006568) | 2.49966112 |
| 74 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 2.48412129 |
| 75 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.46506771 |
| 76 | kynurenine metabolic process (GO:0070189) | 2.45036940 |
| 77 | reverse cholesterol transport (GO:0043691) | 2.44111689 |
| 78 | neuronal action potential propagation (GO:0019227) | 2.44009474 |
| 79 | high-density lipoprotein particle remodeling (GO:0034375) | 2.43208854 |
| 80 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.42591816 |
| 81 | cell wall macromolecule metabolic process (GO:0044036) | 2.40693334 |
| 82 | activated T cell proliferation (GO:0050798) | 2.39998163 |
| 83 | regulation of regulatory T cell differentiation (GO:0045589) | 2.39514692 |
| 84 | regulation of cilium movement (GO:0003352) | 2.39140982 |
| 85 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 2.39115643 |
| 86 | positive regulation of steroid hormone secretion (GO:2000833) | 2.38666122 |
| 87 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.35957028 |
| 88 | regulation of norepinephrine secretion (GO:0014061) | 2.35788623 |
| 89 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.35179576 |
| 90 | rhodopsin mediated signaling pathway (GO:0016056) | 2.33477120 |
| 91 | negative regulation of heart contraction (GO:0045822) | 2.32820759 |
| 92 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.32482498 |
| 93 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.32472828 |
| 94 | negative regulation of T cell apoptotic process (GO:0070233) | 2.31956017 |
| 95 | detection of light stimulus involved in visual perception (GO:0050908) | 2.30673578 |
| 96 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.30673578 |
| 97 | female mating behavior (GO:0060180) | 2.30672956 |
| 98 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.29565731 |
| 99 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2.28770954 |
| 100 | establishment of protein localization to Golgi (GO:0072600) | 2.28364756 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.17334032 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.00272583 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 2.72741605 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.72134589 |
| 5 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.53352705 |
| 6 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.46074685 |
| 7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.42412395 |
| 8 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.31839343 |
| 9 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.25138709 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.20650725 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.17288694 |
| 12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.15842537 |
| 13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.12864535 |
| 14 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.95582037 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.92498033 |
| 16 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.84142645 |
| 17 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.83168378 |
| 18 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.82514133 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 1.76698617 |
| 20 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.73047813 |
| 21 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.70716974 |
| 22 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.70241661 |
| 23 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68257457 |
| 24 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.67081350 |
| 25 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.63841396 |
| 26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.63403666 |
| 27 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.63078210 |
| 28 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.61688378 |
| 29 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.57418944 |
| 30 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.56801448 |
| 31 | STAT3_23295773_ChIP-Seq_U87_Human | 1.56164735 |
| 32 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.53414913 |
| 33 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.51856088 |
| 34 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.50602158 |
| 35 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.49875992 |
| 36 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.48138854 |
| 37 | AR_25329375_ChIP-Seq_VCAP_Human | 1.45557683 |
| 38 | TCF4_23295773_ChIP-Seq_U87_Human | 1.43823389 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42943739 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.41074421 |
| 41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.36373135 |
| 42 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.35738678 |
| 43 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.34432695 |
| 44 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.33628444 |
| 45 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.33541250 |
| 46 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.33222206 |
| 47 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.29385076 |
| 48 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.27967323 |
| 49 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.27758024 |
| 50 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27079290 |
| 51 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27079290 |
| 52 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.27035562 |
| 53 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25973901 |
| 54 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24490696 |
| 55 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.23724104 |
| 56 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.23250722 |
| 57 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.22328816 |
| 58 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.21927627 |
| 59 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.21183293 |
| 60 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.21163722 |
| 61 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20805184 |
| 62 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.20805184 |
| 63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.20014180 |
| 64 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.20014180 |
| 65 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.19059190 |
| 66 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.18915948 |
| 67 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.16632811 |
| 68 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.16005049 |
| 69 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.15914749 |
| 70 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.15818386 |
| 71 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.15559076 |
| 72 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.15179535 |
| 73 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.15179535 |
| 74 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.14751727 |
| 75 | GATA3_26560356_Chip-Seq_TH2_Human | 1.12332812 |
| 76 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.11808894 |
| 77 | GATA2_19941826_ChIP-Seq_K562_Human | 1.11685388 |
| 78 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.10744298 |
| 79 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.10406398 |
| 80 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.10343613 |
| 81 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.10029795 |
| 82 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.09565069 |
| 83 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.09117097 |
| 84 | GATA1_19941826_ChIP-Seq_K562_Human | 1.09023721 |
| 85 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.08532285 |
| 86 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08506620 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08506620 |
| 88 | TP53_16413492_ChIP-PET_HCT116_Human | 1.07876401 |
| 89 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07567342 |
| 90 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07453312 |
| 91 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03800494 |
| 92 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03021606 |
| 93 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.03002539 |
| 94 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.02841775 |
| 95 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.02783711 |
| 96 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.02094577 |
| 97 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.00636793 |
| 98 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.99846537 |
| 99 | GATA1_22025678_ChIP-Seq_K562_Human | 0.99654750 |
| 100 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.99093249 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 6.33851987 |
| 2 | MP0003724_increased_susceptibility_to | 2.95490949 |
| 3 | MP0000569_abnormal_digit_pigmentation | 2.88772226 |
| 4 | MP0008004_abnormal_stomach_pH | 2.82070772 |
| 5 | MP0002736_abnormal_nociception_after | 2.39440584 |
| 6 | MP0008872_abnormal_physiological_respon | 2.26430053 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.23125919 |
| 8 | MP0005167_abnormal_blood-brain_barrier | 2.13389167 |
| 9 | MP0001968_abnormal_touch/_nociception | 2.13165973 |
| 10 | MP0000230_abnormal_systemic_arterial | 2.10092437 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.08479646 |
| 12 | MP0000465_gastrointestinal_hemorrhage | 1.98672408 |
| 13 | MP0008877_abnormal_DNA_methylation | 1.85464980 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 1.80523575 |
| 15 | MP0004130_abnormal_muscle_cell | 1.78138859 |
| 16 | MP0004084_abnormal_cardiac_muscle | 1.77307633 |
| 17 | MP0008775_abnormal_heart_ventricle | 1.75565392 |
| 18 | MP0003195_calcinosis | 1.73889260 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.66579158 |
| 20 | MP0003646_muscle_fatigue | 1.65956498 |
| 21 | MP0005410_abnormal_fertilization | 1.63898200 |
| 22 | MP0005671_abnormal_response_to | 1.63292784 |
| 23 | MP0005083_abnormal_biliary_tract | 1.59348243 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.58169980 |
| 25 | MP0001501_abnormal_sleep_pattern | 1.57439459 |
| 26 | MP0004142_abnormal_muscle_tone | 1.55723402 |
| 27 | MP0004510_myositis | 1.50648947 |
| 28 | MP0002102_abnormal_ear_morphology | 1.45839912 |
| 29 | MP0005174_abnormal_tail_pigmentation | 1.44972824 |
| 30 | MP0010329_abnormal_lipoprotein_level | 1.43082358 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.41155606 |
| 32 | MP0003638_abnormal_response/metabolism_ | 1.35578681 |
| 33 | MP0009046_muscle_twitch | 1.31693321 |
| 34 | MP0002733_abnormal_thermal_nociception | 1.30512024 |
| 35 | MP0009764_decreased_sensitivity_to | 1.27386742 |
| 36 | MP0004036_abnormal_muscle_relaxation | 1.23130009 |
| 37 | MP0004147_increased_porphyrin_level | 1.22730907 |
| 38 | MP0006054_spinal_hemorrhage | 1.21022160 |
| 39 | MP0003011_delayed_dark_adaptation | 1.19805638 |
| 40 | MP0001800_abnormal_humoral_immune | 1.19409851 |
| 41 | MP0002876_abnormal_thyroid_physiology | 1.18783976 |
| 42 | MP0004043_abnormal_pH_regulation | 1.18441266 |
| 43 | MP0001970_abnormal_pain_threshold | 1.18057920 |
| 44 | MP0000372_irregular_coat_pigmentation | 1.14998157 |
| 45 | MP0004215_abnormal_myocardial_fiber | 1.14961704 |
| 46 | MP0001879_abnormal_lymphatic_vessel | 1.14107565 |
| 47 | MP0004484_altered_response_of | 1.13675713 |
| 48 | MP0010386_abnormal_urinary_bladder | 1.12919582 |
| 49 | MP0005000_abnormal_immune_tolerance | 1.12599886 |
| 50 | MP0000383_abnormal_hair_follicle | 1.10792576 |
| 51 | MP0009745_abnormal_behavioral_response | 1.10189337 |
| 52 | MP0002723_abnormal_immune_serum | 1.10090987 |
| 53 | MP0003828_pulmonary_edema | 1.09718176 |
| 54 | MP0003787_abnormal_imprinting | 1.09522079 |
| 55 | MP0000015_abnormal_ear_pigmentation | 1.08063608 |
| 56 | MP0002398_abnormal_bone_marrow | 1.05547890 |
| 57 | MP0003656_abnormal_erythrocyte_physiolo | 1.04478477 |
| 58 | MP0003879_abnormal_hair_cell | 1.04462183 |
| 59 | MP0002638_abnormal_pupillary_reflex | 1.04017487 |
| 60 | MP0001664_abnormal_digestion | 1.02533030 |
| 61 | MP0003866_abnormal_defecation | 1.01829381 |
| 62 | MP0005253_abnormal_eye_physiology | 1.01748583 |
| 63 | MP0003045_fibrosis | 1.01580556 |
| 64 | MP0002148_abnormal_hypersensitivity_rea | 1.01361198 |
| 65 | MP0000343_altered_response_to | 1.00444893 |
| 66 | MP0002693_abnormal_pancreas_physiology | 0.99620364 |
| 67 | MP0002735_abnormal_chemical_nociception | 0.98722411 |
| 68 | MP0008875_abnormal_xenobiotic_pharmacok | 0.98006442 |
| 69 | MP0000689_abnormal_spleen_morphology | 0.97882717 |
| 70 | MP0004883_abnormal_blood_vessel | 0.95948673 |
| 71 | MP0005535_abnormal_body_temperature | 0.94074180 |
| 72 | MP0001986_abnormal_taste_sensitivity | 0.92318681 |
| 73 | MP0001851_eye_inflammation | 0.92312747 |
| 74 | MP0005397_hematopoietic_system_phenotyp | 0.91022452 |
| 75 | MP0001545_abnormal_hematopoietic_system | 0.91022452 |
| 76 | MP0002452_abnormal_antigen_presenting | 0.90863782 |
| 77 | MP0008961_abnormal_basal_metabolism | 0.89621212 |
| 78 | MP0004085_abnormal_heartbeat | 0.88646448 |
| 79 | MP0001663_abnormal_digestive_system | 0.88008416 |
| 80 | MP0010155_abnormal_intestine_physiology | 0.87277972 |
| 81 | MP0009780_abnormal_chondrocyte_physiolo | 0.84238713 |
| 82 | MP0000249_abnormal_blood_vessel | 0.84138506 |
| 83 | MP0001765_abnormal_ion_homeostasis | 0.83963221 |
| 84 | MP0002272_abnormal_nervous_system | 0.83747032 |
| 85 | MP0002420_abnormal_adaptive_immunity | 0.83746222 |
| 86 | MP0003763_abnormal_thymus_physiology | 0.81826393 |
| 87 | MP0001819_abnormal_immune_cell | 0.81728188 |
| 88 | MP0003718_maternal_effect | 0.80969668 |
| 89 | MP0001756_abnormal_urination | 0.80841528 |
| 90 | MP0002132_abnormal_respiratory_system | 0.79467101 |
| 91 | MP0003252_abnormal_bile_duct | 0.78113761 |
| 92 | MP0002837_dystrophic_cardiac_calcinosis | 0.77421334 |
| 93 | MP0000685_abnormal_immune_system | 0.75959197 |
| 94 | MP0009765_abnormal_xenobiotic_induced | 0.75908794 |
| 95 | MP0009642_abnormal_blood_homeostasis | 0.75370861 |
| 96 | MP0002118_abnormal_lipid_homeostasis | 0.75198744 |
| 97 | MP0002067_abnormal_sensory_capabilities | 0.75090525 |
| 98 | MP0005448_abnormal_energy_balance | 0.73895164 |
| 99 | MP0000716_abnormal_immune_system | 0.72223083 |
| 100 | MP0005670_abnormal_white_adipose | 0.72137060 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Prolonged bleeding time (HP:0003010) | 8.17929253 |
| 2 | Menorrhagia (HP:0000132) | 7.07324535 |
| 3 | Increased mean platelet volume (HP:0011877) | 6.63509543 |
| 4 | Abnormal platelet volume (HP:0011876) | 6.24857119 |
| 5 | Petechiae (HP:0000967) | 6.18069571 |
| 6 | Epistaxis (HP:0000421) | 5.34850573 |
| 7 | Purpura (HP:0000979) | 5.33423611 |
| 8 | Gingival bleeding (HP:0000225) | 4.66834605 |
| 9 | Hyperlipoproteinemia (HP:0010980) | 4.61626479 |
| 10 | Abnormal platelet function (HP:0011869) | 3.45984690 |
| 11 | Impaired platelet aggregation (HP:0003540) | 3.45984690 |
| 12 | Pancreatic cysts (HP:0001737) | 3.32000639 |
| 13 | Poikilocytosis (HP:0004447) | 3.30653806 |
| 14 | Dyschromatopsia (HP:0007641) | 3.20540992 |
| 15 | Abnormality of the renal cortex (HP:0011035) | 3.11339237 |
| 16 | Acanthocytosis (HP:0001927) | 2.96527289 |
| 17 | Decreased central vision (HP:0007663) | 2.94275797 |
| 18 | Spontaneous hematomas (HP:0007420) | 2.92021998 |
| 19 | Stomatitis (HP:0010280) | 2.89050149 |
| 20 | Congenital stationary night blindness (HP:0007642) | 2.82103163 |
| 21 | Febrile seizures (HP:0002373) | 2.79512590 |
| 22 | Renal cortical cysts (HP:0000803) | 2.67714077 |
| 23 | Hyperventilation (HP:0002883) | 2.66324949 |
| 24 | Increased density of long bones (HP:0006392) | 2.64915697 |
| 25 | Thyroid-stimulating hormone excess (HP:0002925) | 2.58779365 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.56643964 |
| 27 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.56601995 |
| 28 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.55489778 |
| 29 | Abnormality of alanine metabolism (HP:0010916) | 2.55489778 |
| 30 | Hyperalaninemia (HP:0003348) | 2.55489778 |
| 31 | Attenuation of retinal blood vessels (HP:0007843) | 2.55014026 |
| 32 | Abnormal pupillary function (HP:0007686) | 2.47311172 |
| 33 | Gaze-evoked nystagmus (HP:0000640) | 2.34696582 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.33687416 |
| 35 | True hermaphroditism (HP:0010459) | 2.33546955 |
| 36 | Conjunctival telangiectasia (HP:0000524) | 2.32995113 |
| 37 | Clumsiness (HP:0002312) | 2.27425050 |
| 38 | Medial flaring of the eyebrow (HP:0010747) | 2.25992253 |
| 39 | Abnormal ciliary motility (HP:0012262) | 2.25878867 |
| 40 | Abnormality of midbrain morphology (HP:0002418) | 2.25837947 |
| 41 | Molar tooth sign on MRI (HP:0002419) | 2.25837947 |
| 42 | 3-Methylglutaconic aciduria (HP:0003535) | 2.25565036 |
| 43 | Bruising susceptibility (HP:0000978) | 2.24363718 |
| 44 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.21968332 |
| 45 | Absent/shortened dynein arms (HP:0200106) | 2.21968332 |
| 46 | Congenital sensorineural hearing impairment (HP:0008527) | 2.19390601 |
| 47 | Tinnitus (HP:0000360) | 2.16406330 |
| 48 | Abnormality of the common coagulation pathway (HP:0010990) | 2.10125639 |
| 49 | Polydipsia (HP:0001959) | 2.07081246 |
| 50 | Abnormal drinking behavior (HP:0030082) | 2.07081246 |
| 51 | Joint swelling (HP:0001386) | 2.04212786 |
| 52 | Progressive cerebellar ataxia (HP:0002073) | 2.01242350 |
| 53 | Genetic anticipation (HP:0003743) | 2.01014799 |
| 54 | Nephronophthisis (HP:0000090) | 2.00860464 |
| 55 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.00466339 |
| 56 | Abnormality of the renal medulla (HP:0100957) | 1.99654871 |
| 57 | Central scotoma (HP:0000603) | 1.96233935 |
| 58 | Paralysis (HP:0003470) | 1.94238272 |
| 59 | Abnormality of the prostate (HP:0008775) | 1.94102736 |
| 60 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.92120973 |
| 61 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.92120973 |
| 62 | Atonic seizures (HP:0010819) | 1.90886505 |
| 63 | Widely spaced teeth (HP:0000687) | 1.90872289 |
| 64 | Spontaneous abortion (HP:0005268) | 1.82026243 |
| 65 | Cystic liver disease (HP:0006706) | 1.81209092 |
| 66 | Abnormality of lateral ventricle (HP:0030047) | 1.81088143 |
| 67 | Generalized aminoaciduria (HP:0002909) | 1.80795685 |
| 68 | Encephalitis (HP:0002383) | 1.80583744 |
| 69 | Polyphagia (HP:0002591) | 1.79545553 |
| 70 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.74604950 |
| 71 | Abnormal auditory evoked potentials (HP:0006958) | 1.74248246 |
| 72 | Xanthomatosis (HP:0000991) | 1.72028638 |
| 73 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.71677485 |
| 74 | Chronic hepatic failure (HP:0100626) | 1.71309942 |
| 75 | Hypothermia (HP:0002045) | 1.68453542 |
| 76 | Absent speech (HP:0001344) | 1.67806359 |
| 77 | Enlarged kidneys (HP:0000105) | 1.65310756 |
| 78 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.64041916 |
| 79 | Arthropathy (HP:0003040) | 1.63926371 |
| 80 | Protruding tongue (HP:0010808) | 1.62400074 |
| 81 | Dialeptic seizures (HP:0011146) | 1.62174585 |
| 82 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.61744217 |
| 83 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.59979747 |
| 84 | Tongue fasciculations (HP:0001308) | 1.59708790 |
| 85 | Tubular atrophy (HP:0000092) | 1.59389925 |
| 86 | Congenital hepatic fibrosis (HP:0002612) | 1.57751222 |
| 87 | Biliary tract neoplasm (HP:0100574) | 1.57308153 |
| 88 | Polyuria (HP:0000103) | 1.57171622 |
| 89 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 1.57104350 |
| 90 | Autoimmune thrombocytopenia (HP:0001973) | 1.56704932 |
| 91 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.55853803 |
| 92 | Arterial thrombosis (HP:0004420) | 1.54907661 |
| 93 | Inability to walk (HP:0002540) | 1.54901373 |
| 94 | Fair hair (HP:0002286) | 1.54755883 |
| 95 | Episodic fever (HP:0001954) | 1.54642508 |
| 96 | Diplopia (HP:0000651) | 1.54622283 |
| 97 | Abnormality of binocular vision (HP:0011514) | 1.54622283 |
| 98 | Hypoplastic iliac wings (HP:0002866) | 1.52719848 |
| 99 | Lissencephaly (HP:0001339) | 1.52154119 |
| 100 | IgG deficiency (HP:0004315) | 1.51899082 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.51789100 |
| 2 | ACVR1B | 3.29116394 |
| 3 | RIPK4 | 2.99053644 |
| 4 | TAOK3 | 2.96921465 |
| 5 | MST4 | 2.88447095 |
| 6 | TEC | 2.72250060 |
| 7 | ADRBK2 | 2.41065065 |
| 8 | BMPR1B | 2.35504834 |
| 9 | TXK | 2.23938674 |
| 10 | PIK3CG | 2.14650821 |
| 11 | PTK2B | 1.98635805 |
| 12 | BTK | 1.90761024 |
| 13 | NUAK1 | 1.89800813 |
| 14 | BMX | 1.78555948 |
| 15 | MYLK | 1.77857254 |
| 16 | MAP4K2 | 1.71677101 |
| 17 | SYK | 1.66595810 |
| 18 | GRK5 | 1.62676898 |
| 19 | GRK1 | 1.61999863 |
| 20 | MAPK13 | 1.57933261 |
| 21 | CAMKK2 | 1.55370287 |
| 22 | BMPR2 | 1.52227679 |
| 23 | EIF2AK1 | 1.45319159 |
| 24 | CSF1R | 1.38537517 |
| 25 | TNK2 | 1.36533399 |
| 26 | DAPK2 | 1.34466270 |
| 27 | ADRBK1 | 1.27234198 |
| 28 | ITK | 1.24679587 |
| 29 | INSRR | 1.18666446 |
| 30 | STK3 | 1.18279095 |
| 31 | MAPKAPK3 | 1.15419965 |
| 32 | PINK1 | 1.13922391 |
| 33 | TNIK | 1.10893208 |
| 34 | STK24 | 1.10475602 |
| 35 | IKBKB | 1.08744202 |
| 36 | ZAK | 1.07508401 |
| 37 | STK39 | 1.03579273 |
| 38 | HCK | 0.98254470 |
| 39 | IRAK1 | 0.97859098 |
| 40 | GRK6 | 0.96890164 |
| 41 | PAK3 | 0.93969411 |
| 42 | PLK2 | 0.92138793 |
| 43 | WNK4 | 0.89989759 |
| 44 | LYN | 0.89580467 |
| 45 | ZAP70 | 0.87900208 |
| 46 | WNK3 | 0.82553932 |
| 47 | FES | 0.80069517 |
| 48 | TRIM28 | 0.76396356 |
| 49 | BLK | 0.75172354 |
| 50 | ILK | 0.72088368 |
| 51 | FER | 0.71843784 |
| 52 | NTRK3 | 0.71543765 |
| 53 | PNCK | 0.70773059 |
| 54 | PRKCE | 0.70604945 |
| 55 | TRPM7 | 0.69911148 |
| 56 | NLK | 0.69631643 |
| 57 | FGR | 0.69386541 |
| 58 | AKT3 | 0.68923933 |
| 59 | PRKCQ | 0.67877166 |
| 60 | EPHA3 | 0.66213532 |
| 61 | PDK1 | 0.65983744 |
| 62 | OXSR1 | 0.63929188 |
| 63 | MAP3K4 | 0.63574995 |
| 64 | KIT | 0.62781803 |
| 65 | ERBB2 | 0.62707070 |
| 66 | BRSK2 | 0.60878937 |
| 67 | PKN1 | 0.60352582 |
| 68 | JAK3 | 0.58887557 |
| 69 | CAMK1 | 0.58656924 |
| 70 | MARK3 | 0.53020135 |
| 71 | PHKG2 | 0.52943433 |
| 72 | PHKG1 | 0.52943433 |
| 73 | LCK | 0.51670972 |
| 74 | GRK7 | 0.51592756 |
| 75 | PRKG1 | 0.50644026 |
| 76 | JAK1 | 0.50195966 |
| 77 | FLT3 | 0.49639279 |
| 78 | MAP2K1 | 0.49101795 |
| 79 | SGK2 | 0.48512873 |
| 80 | TGFBR1 | 0.45414244 |
| 81 | PRKCG | 0.43813735 |
| 82 | PRKACG | 0.42147271 |
| 83 | DYRK1A | 0.41577809 |
| 84 | PIK3CA | 0.41427928 |
| 85 | MAP4K1 | 0.40356712 |
| 86 | MATK | 0.39279041 |
| 87 | CAMK2A | 0.38766257 |
| 88 | ERBB3 | 0.38139033 |
| 89 | JAK2 | 0.36884581 |
| 90 | MKNK2 | 0.35451038 |
| 91 | PRKD1 | 0.34982913 |
| 92 | CAMK1G | 0.34337737 |
| 93 | ABL1 | 0.34138688 |
| 94 | PRKAA2 | 0.34056794 |
| 95 | IGF1R | 0.33156630 |
| 96 | PRKACA | 0.32749596 |
| 97 | MAP3K2 | 0.32357266 |
| 98 | TLK1 | 0.32211568 |
| 99 | CCNB1 | 0.31384360 |
| 100 | PRKCA | 0.30473858 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 3.70125963 |
| 2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.69575618 |
| 3 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.54824279 |
| 4 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.39757949 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 2.33439092 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.33316137 |
| 7 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.18427356 |
| 8 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.93897392 |
| 9 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.83187831 |
| 10 | Olfactory transduction_Homo sapiens_hsa04740 | 1.74117642 |
| 11 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.68723777 |
| 12 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.65168707 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.64896222 |
| 14 | Morphine addiction_Homo sapiens_hsa05032 | 1.55922191 |
| 15 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.54557023 |
| 16 | Circadian entrainment_Homo sapiens_hsa04713 | 1.50808776 |
| 17 | ABC transporters_Homo sapiens_hsa02010 | 1.46595205 |
| 18 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.37828495 |
| 19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.37811863 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.35716479 |
| 21 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.27513954 |
| 22 | Long-term depression_Homo sapiens_hsa04730 | 1.27200355 |
| 23 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.26676213 |
| 24 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.22205284 |
| 25 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.21904485 |
| 26 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.17515801 |
| 27 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.16201185 |
| 28 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.15842148 |
| 29 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.14916590 |
| 30 | GABAergic synapse_Homo sapiens_hsa04727 | 1.14512075 |
| 31 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.13921994 |
| 32 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.13472325 |
| 33 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.12988699 |
| 34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.08096885 |
| 35 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.04544339 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.03394843 |
| 37 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.03305085 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.00863595 |
| 39 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.99948994 |
| 40 | Renin secretion_Homo sapiens_hsa04924 | 0.98756644 |
| 41 | Salivary secretion_Homo sapiens_hsa04970 | 0.97648616 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.96510819 |
| 43 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.96264837 |
| 44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.92945314 |
| 45 | Nicotine addiction_Homo sapiens_hsa05033 | 0.92674498 |
| 46 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.92511943 |
| 47 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.92291628 |
| 48 | Asthma_Homo sapiens_hsa05310 | 0.91920248 |
| 49 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.90527276 |
| 50 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.88186465 |
| 51 | Taste transduction_Homo sapiens_hsa04742 | 0.87775473 |
| 52 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.87134670 |
| 53 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.86760338 |
| 54 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85161601 |
| 55 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.81840560 |
| 56 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.81782153 |
| 57 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.80802795 |
| 58 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.80586031 |
| 59 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.80577864 |
| 60 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.77528985 |
| 61 | Allograft rejection_Homo sapiens_hsa05330 | 0.77044516 |
| 62 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.76158520 |
| 63 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.74299846 |
| 64 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.73328977 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.73240093 |
| 66 | Gap junction_Homo sapiens_hsa04540 | 0.73024454 |
| 67 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.72813042 |
| 68 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.71149656 |
| 69 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.68577728 |
| 70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66258552 |
| 71 | Circadian rhythm_Homo sapiens_hsa04710 | 0.65053751 |
| 72 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.65027175 |
| 73 | Alcoholism_Homo sapiens_hsa05034 | 0.64667192 |
| 74 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.64137192 |
| 75 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.63139755 |
| 76 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.62476519 |
| 77 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.61987369 |
| 78 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.60523575 |
| 79 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.59608593 |
| 80 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.57989234 |
| 81 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.56884718 |
| 82 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.56373745 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55821478 |
| 84 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.55440855 |
| 85 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.53752101 |
| 86 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.53701636 |
| 87 | Insulin secretion_Homo sapiens_hsa04911 | 0.53469935 |
| 88 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.51503354 |
| 89 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.46335735 |
| 90 | Homologous recombination_Homo sapiens_hsa03440 | 0.45879675 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.45678299 |
| 92 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.45560881 |
| 93 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44559393 |
| 94 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.43730179 |
| 95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.43521631 |
| 96 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.39566190 |
| 97 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39499050 |
| 98 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.39073101 |
| 99 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.38813206 |
| 100 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.38234083 |

