WNK2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.38792763
2synaptic vesicle maturation (GO:0016188)5.13548794
3vocalization behavior (GO:0071625)5.09449324
4locomotory exploration behavior (GO:0035641)4.97348458
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.80225632
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.78198781
7synaptic vesicle docking involved in exocytosis (GO:0016081)4.72520850
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.62072929
9synaptic vesicle exocytosis (GO:0016079)4.50939608
10glutamate secretion (GO:0014047)4.42656633
11layer formation in cerebral cortex (GO:0021819)4.28158853
12regulation of synaptic vesicle exocytosis (GO:2000300)4.26153840
13regulation of synapse structural plasticity (GO:0051823)4.23984972
14membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.23027005
15regulation of glutamate receptor signaling pathway (GO:1900449)4.22143949
16cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.16610926
17cell communication by electrical coupling (GO:0010644)4.06606574
18protein localization to synapse (GO:0035418)3.92489284
19dendritic spine morphogenesis (GO:0060997)3.89684485
20ionotropic glutamate receptor signaling pathway (GO:0035235)3.89601228
21regulation of synaptic vesicle transport (GO:1902803)3.85602731
22neuronal action potential propagation (GO:0019227)3.84296199
23neuron cell-cell adhesion (GO:0007158)3.82900608
24neurotransmitter secretion (GO:0007269)3.82605830
25sodium ion export (GO:0071436)3.77340233
26exploration behavior (GO:0035640)3.76582442
27cardiac myofibril assembly (GO:0055003)3.75430137
28cellular potassium ion homeostasis (GO:0030007)3.75008500
29sarcoplasmic reticulum calcium ion transport (GO:0070296)3.72521805
30gamma-aminobutyric acid transport (GO:0015812)3.60077085
31regulation of neuronal synaptic plasticity (GO:0048168)3.59433359
32synaptic transmission, glutamatergic (GO:0035249)3.58599973
33neurotransmitter-gated ion channel clustering (GO:0072578)3.56758274
34positive regulation of synapse maturation (GO:0090129)3.54363071
35glutamate receptor signaling pathway (GO:0007215)3.54119938
36regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.52800801
37regulation of long-term neuronal synaptic plasticity (GO:0048169)3.52447709
38cell communication involved in cardiac conduction (GO:0086065)3.50721186
39cerebellar Purkinje cell differentiation (GO:0021702)3.46325053
40positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.44949079
41myofibril assembly (GO:0030239)3.42663646
42positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.41586341
43long-term memory (GO:0007616)3.39518388
44regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.38613834
45regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.35124473
46regulation of membrane repolarization (GO:0060306)3.33415959
47neuron recognition (GO:0008038)3.32800584
48regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.32054883
49membrane depolarization during action potential (GO:0086010)3.31844195
50activation of protein kinase A activity (GO:0034199)3.31425342
51cerebellar granule cell differentiation (GO:0021707)3.30929037
52regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.28094825
53regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.27486913
54cell migration in hindbrain (GO:0021535)3.26795004
55axonal fasciculation (GO:0007413)3.26757991
56dendrite morphogenesis (GO:0048813)3.26317733
57neuron-neuron synaptic transmission (GO:0007270)3.25774344
58regulation of actin filament-based movement (GO:1903115)3.23958313
59auditory behavior (GO:0031223)3.20025864
60sarcomere organization (GO:0045214)3.20006097
61muscle filament sliding (GO:0030049)3.19249102
62actin-myosin filament sliding (GO:0033275)3.19249102
63regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.19138881
64proline transport (GO:0015824)3.18149273
65regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.16686229
66ventricular cardiac muscle cell action potential (GO:0086005)3.16559975
67regulation of excitatory postsynaptic membrane potential (GO:0060079)3.14959113
68positive regulation of potassium ion transmembrane transport (GO:1901381)3.14296515
69positive regulation of membrane potential (GO:0045838)3.11700133
70postsynaptic membrane organization (GO:0001941)3.10683330
71synaptic vesicle endocytosis (GO:0048488)3.10307460
72striated muscle contraction (GO:0006941)3.10190349
73potassium ion import (GO:0010107)3.09338335
74G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.09004400
75neuronal ion channel clustering (GO:0045161)3.08717342
76neuromuscular process controlling balance (GO:0050885)3.07622013
77regulation of dendritic spine morphogenesis (GO:0061001)3.07020404
78regulation of postsynaptic membrane potential (GO:0060078)3.05564819
79neurotransmitter transport (GO:0006836)3.02610102
80cellular sodium ion homeostasis (GO:0006883)2.99028997
81positive regulation of dendritic spine morphogenesis (GO:0061003)2.98428057
82plasma membrane repair (GO:0001778)2.95966988
83negative regulation of cytosolic calcium ion concentration (GO:0051481)2.95154838
84establishment of nucleus localization (GO:0040023)2.94671541
85response to auditory stimulus (GO:0010996)2.94456021
86negative regulation of potassium ion transmembrane transport (GO:1901380)2.91190720
87neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.90810801
88regulation of neurotransmitter secretion (GO:0046928)2.88723476
89response to pheromone (GO:0019236)2.87636658
90potassium ion homeostasis (GO:0055075)2.86954294
91regulation of synaptic plasticity (GO:0048167)2.86377467
92membrane hyperpolarization (GO:0060081)2.84667905
93cardiac muscle hypertrophy (GO:0003300)2.84405495
94membrane depolarization (GO:0051899)2.84163203
95negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.83861394
96detection of calcium ion (GO:0005513)2.83319586
97response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.82974472
98cardiac conduction (GO:0061337)2.82163044
99central nervous system projection neuron axonogenesis (GO:0021952)2.81444107
100regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.81353348
101positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.81318885
102regulation of calcium ion transmembrane transport (GO:1903169)2.81179700
103regulation of calcium ion transmembrane transporter activity (GO:1901019)2.81179700
104positive regulation of dendritic spine development (GO:0060999)2.81152615
105cardiac muscle contraction (GO:0060048)2.80660004
106innervation (GO:0060384)2.80172852
107membrane repolarization (GO:0086009)2.79640308
108establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.79545115
109mitochondrion transport along microtubule (GO:0047497)2.79545115
110establishment of mitochondrion localization (GO:0051654)2.78781132
111positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.77908876
112regulation of voltage-gated calcium channel activity (GO:1901385)2.77898580
113regulation of neurotransmitter levels (GO:0001505)2.77649318
114transmission of nerve impulse (GO:0019226)2.76757829
115regulation of cell communication by electrical coupling (GO:0010649)2.76483122
116dendritic spine organization (GO:0097061)2.75959086
117positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.75809265
118synapse assembly (GO:0007416)2.75774562
119regulation of synapse maturation (GO:0090128)2.74669418
120creatine metabolic process (GO:0006600)2.73110416
121negative regulation of catenin import into nucleus (GO:0035414)2.72179384
122neuromuscular synaptic transmission (GO:0007274)2.70917232
123cytoskeletal anchoring at plasma membrane (GO:0007016)2.69682851
124striated muscle hypertrophy (GO:0014897)2.68613763
125regulation of heart rate by cardiac conduction (GO:0086091)2.68192225
126cardiac muscle cell action potential (GO:0086001)2.67552774
127cell junction maintenance (GO:0034331)2.67078180
128cardiac muscle cell action potential involved in contraction (GO:0086002)2.66630293
129cell-cell junction maintenance (GO:0045217)2.61317388
130response to inactivity (GO:0014854)2.60475752
131actin-mediated cell contraction (GO:0070252)2.58073454
132axon ensheathment in central nervous system (GO:0032291)2.56249061
133central nervous system myelination (GO:0022010)2.56249061
134positive regulation of dendrite development (GO:1900006)2.55115040
135embryonic retina morphogenesis in camera-type eye (GO:0060059)2.53229563
136actomyosin structure organization (GO:0031032)2.52386843
137multicellular organismal signaling (GO:0035637)2.49012275
138presynaptic membrane organization (GO:0097090)2.47269069
139regulation of cardiac muscle cell contraction (GO:0086004)2.46472207

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.85987681
2SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.82467863
3* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.80339732
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.77643185
5DROSHA_22980978_ChIP-Seq_HELA_Human2.76677125
6GBX2_23144817_ChIP-Seq_PC3_Human2.65995547
7* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.63508086
8* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.63508086
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.50058315
10* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.50048135
11REST_21632747_ChIP-Seq_MESCs_Mouse2.48757130
12RARB_27405468_Chip-Seq_BRAIN_Mouse2.42665221
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.36015293
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.35922480
15* EZH2_27294783_Chip-Seq_ESCs_Mouse2.35045127
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.32355068
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.28881818
18* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.23887968
19* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.23865589
20* RNF2_27304074_Chip-Seq_ESCs_Mouse2.20841841
21* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.19444492
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.08935955
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.08774410
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.04050047
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.98291600
26IKZF1_21737484_ChIP-ChIP_HCT116_Human1.80644315
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.79329265
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.74700066
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.67040690
30AR_21572438_ChIP-Seq_LNCaP_Human1.60838455
31* ERG_21242973_ChIP-ChIP_JURKAT_Human1.55970723
32ESR2_21235772_ChIP-Seq_MCF-7_Human1.54972913
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.53678959
34LXR_22292898_ChIP-Seq_THP-1_Human1.48990406
35RING1B_27294783_Chip-Seq_ESCs_Mouse1.43204342
36KDM2B_26808549_Chip-Seq_K562_Human1.40679167
37ZFP281_18757296_ChIP-ChIP_E14_Mouse1.39231721
38* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39053620
39* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37146909
40DNAJC2_21179169_ChIP-ChIP_NT2_Human1.36747376
41ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.36603529
42SMAD4_21799915_ChIP-Seq_A2780_Human1.34904263
43ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.31886967
44RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.30335379
45* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.29768580
46ISL1_27105846_Chip-Seq_CPCs_Mouse1.29462262
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.29452695
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27449422
49* AR_19668381_ChIP-Seq_PC3_Human1.27370769
50SOX2_21211035_ChIP-Seq_LN229_Gbm1.26931321
51ZNF274_21170338_ChIP-Seq_K562_Hela1.26814984
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.23178452
53CREB1_26743006_Chip-Seq_LNCaP_Human1.22989807
54* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.22945500
55PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21729786
56WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.21649468
57SMC4_20622854_ChIP-Seq_HELA_Human1.21384297
58CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.21374628
59SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.19970532
60* RING1B_27294783_Chip-Seq_NPCs_Mouse1.19550995
61CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17595151
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.17259996
63CBX2_27304074_Chip-Seq_ESCs_Mouse1.16309490
64SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15861444
65EP300_21415370_ChIP-Seq_HL-1_Mouse1.15386118
66* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14865041
67NR3C1_23031785_ChIP-Seq_PC12_Mouse1.13945577
68AHR_22903824_ChIP-Seq_MCF-7_Human1.12367439
69RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.10134017
70ARNT_22903824_ChIP-Seq_MCF-7_Human1.09934093
71RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09592444
72PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.09230814
73GATA1_26923725_Chip-Seq_HPCs_Mouse1.08773663
74EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.08520911
75* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.06626834
76SMAD3_21741376_ChIP-Seq_EPCs_Human1.06243279
77CTCF_27219007_Chip-Seq_Bcells_Human1.06196990
78ESR1_20079471_ChIP-ChIP_T-47D_Human1.06062277
79NFIB_24661679_ChIP-Seq_LUNG_Mouse1.05202525
80OCT4_19829295_ChIP-Seq_ESCs_Human1.03738857
81SMAD4_21741376_ChIP-Seq_HESCs_Human1.03405736
82ZFP281_27345836_Chip-Seq_ESCs_Mouse1.02642511
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02546962
84AR_25329375_ChIP-Seq_VCAP_Human1.01828912
85* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01321779
86* STAT3_23295773_ChIP-Seq_U87_Human1.00501222
87SMAD3_21741376_ChIP-Seq_HESCs_Human0.99861800
88TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99284941
89RNF2_27304074_Chip-Seq_NSC_Mouse0.98752865
90OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98495130
91TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.98238076
92P68_20966046_ChIP-Seq_HELA_Human0.97761927
93* RACK7_27058665_Chip-Seq_MCF-7_Human0.97088168
94DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.96392554
95MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95991653
96KDM2B_26808549_Chip-Seq_DND41_Human0.95925979
97TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95822529
98* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94875801
99CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.93354989
100SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.93098723
101PIAS1_25552417_ChIP-Seq_VCAP_Human0.92583864
102TET1_21490601_ChIP-Seq_MESCs_Mouse0.92194408
103TP53_20018659_ChIP-ChIP_R1E_Mouse0.91897515
104TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91726360
105SMAD3_21741376_ChIP-Seq_ESCs_Human0.91646569
106KDM2B_26808549_Chip-Seq_SUP-B15_Human0.90922452
107MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.89962156
108TCF4_23295773_ChIP-Seq_U87_Human0.89855304
109SMAD_19615063_ChIP-ChIP_OVARY_Human0.89666118
110MYC_27129775_Chip-Seq_CORNEA_Mouse0.89476138
111TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89411209
112POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89411209
113THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.88486458
114TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87401534
115PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.86703066
116NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.86667071
117* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.86027998
118FOXA2_19822575_ChIP-Seq_HepG2_Human0.85785251
119CTNNB1_20460455_ChIP-Seq_HCT116_Human0.84158866
120CDX2_20551321_ChIP-Seq_CACO-2_Human0.83367848
121BMI1_23680149_ChIP-Seq_NPCS_Mouse0.83261832
122VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.82431857
123POU5F1_16518401_ChIP-PET_MESCs_Mouse0.81783631
124UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.81375433
125P300_19829295_ChIP-Seq_ESCs_Human0.81343257
126GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81265748
127KDM2B_26808549_Chip-Seq_JURKAT_Human0.81175437
128STAT6_21828071_ChIP-Seq_BEAS2B_Human0.81076572
129TBX20_22080862_ChIP-Seq_HEART_Mouse0.80734428
130TBX20_22328084_ChIP-Seq_HEART_Mouse0.80734428
131TP53_23651856_ChIP-Seq_MEFs_Mouse0.79821247
132RUNX1_27514584_Chip-Seq_MCF-7_Human0.79394672

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.56175417
2MP0003880_abnormal_central_pattern3.61925859
3MP0003635_abnormal_synaptic_transmissio3.51173571
4MP0004270_analgesia3.37985867
5MP0000566_synostosis2.86116219
6MP0000751_myopathy2.81279223
7MP0002063_abnormal_learning/memory/cond2.79387627
8MP0009745_abnormal_behavioral_response2.67145959
9MP0002837_dystrophic_cardiac_calcinosis2.66714292
10MP0009046_muscle_twitch2.65334879
11MP0005423_abnormal_somatic_nervous2.62824088
12MP0003646_muscle_fatigue2.60846943
13MP0002064_seizures2.50595119
14MP0002734_abnormal_mechanical_nocicepti2.29326876
15MP0002572_abnormal_emotion/affect_behav2.27556513
16MP0001486_abnormal_startle_reflex2.17949695
17MP0004215_abnormal_myocardial_fiber2.15632610
18MP0004145_abnormal_muscle_electrophysio2.15166490
19MP0001968_abnormal_touch/_nociception2.14204197
20MP0002272_abnormal_nervous_system2.11473208
21MP0009780_abnormal_chondrocyte_physiolo2.09238810
22MP0002822_catalepsy1.95518955
23MP0008569_lethality_at_weaning1.92949717
24MP0000778_abnormal_nervous_system1.89200224
25MP0002909_abnormal_adrenal_gland1.87557604
26MP0005670_abnormal_white_adipose1.86666926
27MP0004858_abnormal_nervous_system1.85740326
28MP0002249_abnormal_larynx_morphology1.81665406
29MP0001440_abnormal_grooming_behavior1.77191875
30MP0002184_abnormal_innervation1.76820088
31MP0002067_abnormal_sensory_capabilities1.76307361
32MP0002735_abnormal_chemical_nociception1.69786658
33MP0003123_paternal_imprinting1.67402576
34MP0003137_abnormal_impulse_conducting1.65683278
35MP0001501_abnormal_sleep_pattern1.64492764
36MP0003879_abnormal_hair_cell1.63038924
37MP0004084_abnormal_cardiac_muscle1.61302508
38MP0002557_abnormal_social/conspecific_i1.60904890
39MP0004811_abnormal_neuron_physiology1.59213756
40MP0004924_abnormal_behavior1.58456641
41MP0005386_behavior/neurological_phenoty1.58456641
42MP0002733_abnormal_thermal_nociception1.55445304
43MP0004036_abnormal_muscle_relaxation1.53974610
44MP0004885_abnormal_endolymph1.51961984
45MP0001970_abnormal_pain_threshold1.49169676
46MP0003787_abnormal_imprinting1.48239171
47MP0002736_abnormal_nociception_after1.46848461
48MP0005409_darkened_coat_color1.46398451
49MP0000749_muscle_degeneration1.45136090
50MP0000955_abnormal_spinal_cord1.41592237
51MP0003329_amyloid_beta_deposits1.37490648
52MP0004085_abnormal_heartbeat1.37091165
53MP0000537_abnormal_urethra_morphology1.36436916
54MP0001984_abnormal_olfaction1.35227617
55MP0002882_abnormal_neuron_morphology1.34329614
56MP0006276_abnormal_autonomic_nervous1.33622267
57MP0004233_abnormal_muscle_weight1.32316596
58MP0005646_abnormal_pituitary_gland1.31621854
59MP0002066_abnormal_motor_capabilities/c1.27013879
60MP0005620_abnormal_muscle_contractility1.24765829
61MP0001502_abnormal_circadian_rhythm1.23761288
62MP0004484_altered_response_of1.19691895
63MP0001346_abnormal_lacrimal_gland1.19677768
64MP0001188_hyperpigmentation1.19052472
65MP0010630_abnormal_cardiac_muscle1.18241365
66MP0004130_abnormal_muscle_cell1.17408825
67MP0004087_abnormal_muscle_fiber1.15817827
68MP0000569_abnormal_digit_pigmentation1.13277060
69MP0000013_abnormal_adipose_tissue1.11685217
70MP0002972_abnormal_cardiac_muscle1.10953753
71MP0005645_abnormal_hypothalamus_physiol1.10792073
72MP0002234_abnormal_pharynx_morphology1.09350912
73MP0002152_abnormal_brain_morphology1.09086695
74MP0005394_taste/olfaction_phenotype1.08544300
75MP0005499_abnormal_olfactory_system1.08544300
76MP0003633_abnormal_nervous_system1.06833511
77MP0000747_muscle_weakness1.06459298
78MP0002106_abnormal_muscle_physiology1.06075373
79MP0002638_abnormal_pupillary_reflex1.06035135
80MP0003878_abnormal_ear_physiology1.01152652
81MP0005377_hearing/vestibular/ear_phenot1.01152652
82MP0000579_abnormal_nail_morphology1.00868141
83MP0005330_cardiomyopathy1.00585258
84MP0003122_maternal_imprinting0.99268902
85MP0001485_abnormal_pinna_reflex0.98487324
86MP0002653_abnormal_ependyma_morphology0.96450151
87MP0008961_abnormal_basal_metabolism0.95595942
88MP0005187_abnormal_penis_morphology0.94423223
89MP0002269_muscular_atrophy0.94356128
90MP0004142_abnormal_muscle_tone0.93896227
91MP0000759_abnormal_skeletal_muscle0.90946106
92MP0003283_abnormal_digestive_organ0.90169548
93MP0003631_nervous_system_phenotype0.89349761
94MP0005369_muscle_phenotype0.89132949
95MP0005551_abnormal_eye_electrophysiolog0.87561833
96MP0002229_neurodegeneration0.84397637
97MP0000026_abnormal_inner_ear0.84076995
98MP0004510_myositis0.84005457
99MP0004742_abnormal_vestibular_system0.82718811
100MP0003938_abnormal_ear_development0.81985111
101MP0002069_abnormal_eating/drinking_beha0.80381821
102MP0005666_abnormal_adipose_tissue0.78184452
103MP0008775_abnormal_heart_ventricle0.78119912
104MP0003121_genomic_imprinting0.77382756
105MP0002089_abnormal_postnatal_growth/wei0.77080292
106MP0002752_abnormal_somatic_nervous0.76350336
107MP0001529_abnormal_vocalization0.74519589
108MP0000631_abnormal_neuroendocrine_gland0.74228254
109MP0003119_abnormal_digestive_system0.74095685
110MP0010030_abnormal_orbit_morphology0.73710129
111MP0005385_cardiovascular_system_phenoty0.73012494
112MP0005623_abnormal_meninges_morphology0.73011604
113MP0006072_abnormal_retinal_apoptosis0.71906398
114MP0006138_congestive_heart_failure0.71072312
115MP0001299_abnormal_eye_distance/0.70321766
116MP0001905_abnormal_dopamine_level0.69169786
117MP0003861_abnormal_nervous_system0.68896464
118MP0003634_abnormal_glial_cell0.68597319
119MP0001963_abnormal_hearing_physiology0.65397510
120MP0000750_abnormal_muscle_regeneration0.65152160
121MP0001544_abnormal_cardiovascular_syste0.64315294

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.51265347
2Myokymia (HP:0002411)5.06280587
3Focal seizures (HP:0007359)4.45483503
4Visual hallucinations (HP:0002367)4.26055167
5Sudden death (HP:0001699)4.00355982
6Exercise-induced myalgia (HP:0003738)3.81996830
7Epileptic encephalopathy (HP:0200134)3.73825331
8Progressive cerebellar ataxia (HP:0002073)3.70664261
9Ventricular fibrillation (HP:0001663)3.67193229
10Febrile seizures (HP:0002373)3.57131348
11Bundle branch block (HP:0011710)3.43938237
12Action tremor (HP:0002345)3.34203106
13Poor eye contact (HP:0000817)3.23079326
14Broad-based gait (HP:0002136)3.22546649
15Atonic seizures (HP:0010819)3.15471091
16Genetic anticipation (HP:0003743)3.10523091
17Prolonged QT interval (HP:0001657)3.09093642
18Absence seizures (HP:0002121)3.03109567
19Calf muscle hypertrophy (HP:0008981)3.03049637
20Impaired social interactions (HP:0000735)3.00900877
21Abnormal social behavior (HP:0012433)3.00900877
22Ankle clonus (HP:0011448)3.00605494
23Muscle hypertrophy of the lower extremities (HP:0008968)2.97179307
24Dysmetric saccades (HP:0000641)2.96467777
25Generalized tonic-clonic seizures (HP:0002069)2.95972034
26Atrial fibrillation (HP:0005110)2.92258294
27Primary atrial arrhythmia (HP:0001692)2.87566621
28Syncope (HP:0001279)2.87471155
29Depression (HP:0000716)2.81255886
30Supranuclear gaze palsy (HP:0000605)2.78054621
31Dysdiadochokinesis (HP:0002075)2.73971103
32Gaze-evoked nystagmus (HP:0000640)2.73895913
33Supraventricular tachycardia (HP:0004755)2.70252991
34Abnormal EKG (HP:0003115)2.70192454
35Urinary bladder sphincter dysfunction (HP:0002839)2.68323335
36Dialeptic seizures (HP:0011146)2.68231265
37Exercise-induced muscle cramps (HP:0003710)2.67116161
38Bronchomalacia (HP:0002780)2.63530474
39Abnormality of the calf musculature (HP:0001430)2.63384345
40Impaired vibration sensation in the lower limbs (HP:0002166)2.63341667
41Supraventricular arrhythmia (HP:0005115)2.62440345
42Hepatoblastoma (HP:0002884)2.59584354
43Muscle fiber inclusion bodies (HP:0100299)2.58622975
44Difficulty running (HP:0009046)2.57720758
45EMG: neuropathic changes (HP:0003445)2.57663320
46Type 1 muscle fiber predominance (HP:0003803)2.53760528
47Myotonia (HP:0002486)2.51129585
48Anxiety (HP:0000739)2.49349500
49Abnormality of the aortic arch (HP:0012303)2.48600471
50Hyperventilation (HP:0002883)2.43874037
51Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.41549637
52Abnormality of the lower motor neuron (HP:0002366)2.41326946
53Ventricular arrhythmia (HP:0004308)2.41081423
54Postural instability (HP:0002172)2.39296558
55Amblyopia (HP:0000646)2.39158458
56Megalencephaly (HP:0001355)2.35953701
57Dysmetria (HP:0001310)2.34012550
58Hemiplegia (HP:0002301)2.29555254
59Hemiparesis (HP:0001269)2.28027751
60Truncal ataxia (HP:0002078)2.27133543
61Urinary urgency (HP:0000012)2.26674985
62Nemaline bodies (HP:0003798)2.26621653
63Sleep apnea (HP:0010535)2.26009241
64Ventricular tachycardia (HP:0004756)2.24719060
65Drooling (HP:0002307)2.24183284
66Excessive salivation (HP:0003781)2.24183284
67Stereotypic behavior (HP:0000733)2.23125871
68Myopathic facies (HP:0002058)2.22079596
69Mutism (HP:0002300)2.21670815
70Heart block (HP:0012722)2.20987726
71Pheochromocytoma (HP:0002666)2.19224724
72Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.18265314
73Abnormal eating behavior (HP:0100738)2.16896651
74Mildly elevated creatine phosphokinase (HP:0008180)2.16570540
75Hyporeflexia of lower limbs (HP:0002600)2.16490769
76Impaired smooth pursuit (HP:0007772)2.12133820
77Alacrima (HP:0000522)2.07228073
78Subaortic stenosis (HP:0001682)2.04466041
79Abnormality of the left ventricular outflow tract (HP:0011103)2.04466041
80Lower limb amyotrophy (HP:0007210)2.04238811
81Central scotoma (HP:0000603)2.02960573
82Turricephaly (HP:0000262)2.01444782
83Muscle fiber splitting (HP:0003555)2.00927310
84Epileptiform EEG discharges (HP:0011182)2.00392861
85EMG: myopathic abnormalities (HP:0003458)1.99867621
86Abnormal atrioventricular conduction (HP:0005150)1.99630210
87Centrally nucleated skeletal muscle fibers (HP:0003687)1.99482487
88Obstructive sleep apnea (HP:0002870)1.98958774
89Partial duplication of thumb phalanx (HP:0009944)1.98529165
90EEG with generalized epileptiform discharges (HP:0011198)1.97942254
91Insomnia (HP:0100785)1.97711918
92Abnormality of the foot musculature (HP:0001436)1.96584952
93Torticollis (HP:0000473)1.96410757
94Fetal akinesia sequence (HP:0001989)1.95618628
95Lower limb muscle weakness (HP:0007340)1.91654539
96Insidious onset (HP:0003587)1.91479481
97Termporal pattern (HP:0011008)1.91479481
98Congenital malformation of the right heart (HP:0011723)1.90906059
99Double outlet right ventricle (HP:0001719)1.90906059
100Hyperkalemia (HP:0002153)1.90899376
101Dilated cardiomyopathy (HP:0001644)1.90347808
102Spastic gait (HP:0002064)1.90130356
103Hypsarrhythmia (HP:0002521)1.89796824
104Pointed chin (HP:0000307)1.87864803
105Intention tremor (HP:0002080)1.86240879
106Progressive inability to walk (HP:0002505)1.84325035
107Abnormality of ocular smooth pursuit (HP:0000617)1.83540908
108Papilledema (HP:0001085)1.82363141
109Agitation (HP:0000713)1.82072662
110Foot dorsiflexor weakness (HP:0009027)1.82046559
111Aplasia involving bones of the extremities (HP:0009825)1.81697212
112Aplasia involving bones of the upper limbs (HP:0009823)1.81697212
113Aplasia of the phalanges of the hand (HP:0009802)1.81697212
114Shallow orbits (HP:0000586)1.81671447
115Scanning speech (HP:0002168)1.81153237
116Choanal stenosis (HP:0000452)1.80662923
117Hyperacusis (HP:0010780)1.80187139
118Atrioventricular block (HP:0001678)1.79278560
119Trigonocephaly (HP:0000243)1.78280752
120Right ventricular cardiomyopathy (HP:0011663)1.77347227
121Rapidly progressive (HP:0003678)1.77111527
122Lipoatrophy (HP:0100578)1.76722159
123Diplopia (HP:0000651)1.76428610
124Abnormality of binocular vision (HP:0011514)1.76428610
125Frequent falls (HP:0002359)1.75702619
126Focal dystonia (HP:0004373)1.75660513
127Bradykinesia (HP:0002067)1.75596104
128Left ventricular hypertrophy (HP:0001712)1.75577289
129Difficulty climbing stairs (HP:0003551)1.66464811
130Rimmed vacuoles (HP:0003805)1.62533248
131Status epilepticus (HP:0002133)1.59565981
132Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.59288274
133Abnormality of the fingertips (HP:0001211)1.58763891
134Tracheomalacia (HP:0002779)1.57971805

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.81031791
2NTRK33.40786985
3MAP3K93.25238396
4EPHA43.24101702
5MAP3K42.77045529
6PHKG12.74291458
7PHKG22.74291458
8CAMK1D2.56705858
9DAPK22.42705090
10PAK62.29870435
11NTRK22.24842788
12EEF2K2.22266835
13MINK12.20839110
14PRKD32.20705723
15MAP2K71.99576030
16LMTK21.93643470
17CAMKK11.70977186
18MAP2K41.69153643
19STK381.58703982
20FGFR21.55160306
21CDK121.53724696
22KSR11.48308000
23KSR21.48167341
24PINK11.47707783
25TAOK11.44644687
26DMPK1.40081316
27MAPK131.39765355
28RIPK11.38195155
29CDK51.36738777
30TNIK1.34752911
31TYRO31.32164070
32PRPF4B1.25700284
33SIK21.25577382
34NTRK11.20700804
35CASK1.18097817
36LATS21.14871727
37TTN1.09761138
38CDK191.09181480
39SGK4941.08623855
40SGK2231.08623855
41UHMK11.07843062
42DAPK11.07431933
43SIK11.06411736
44PAK31.06068698
45SGK21.05706722
46STK111.02203385
47SGK31.01475112
48NEK11.01405439
49PLK20.98226544
50MAPK150.97738134
51PRKCG0.96650366
52EPHA20.96548738
53CDC42BPA0.95845354
54CAMKK20.94540986
55CAMK10.94476357
56FGFR40.93591742
57TNK20.91827302
58GRK50.90105061
59PRKCH0.89121293
60DYRK1B0.88927736
61MAP3K100.88920181
62MAP3K70.87960398
63MTOR0.87402803
64CAMK2A0.86802147
65TRIB30.83671401
66OBSCN0.83596508
67MAP3K120.83492633
68CAMK1G0.81183233
69ERBB20.81044726
70MARK20.79297252
71PNCK0.77542888
72PKN20.77540129
73CAMK40.76953835
74RET0.76499583
75ERBB30.75978621
76MUSK0.75468501
77SGK10.71900908
78SMG10.71416469
79CDK180.70068122
80CDK150.69420200
81DYRK1A0.67163329
82PRKAA20.66641974
83MAPK100.65520629
84MAP3K20.64176086
85CAMK2D0.63006320
86ALK0.62707030
87PIK3CA0.61651811
88NME10.61028517
89RIPK40.60506032
90PDK40.60499884
91PDK30.60499884
92MST1R0.60106722
93CDK140.59925415
94CDK11A0.58950253
95ROCK10.58129811
96ICK0.58062138
97WNK40.57037970
98PRKAA10.56795483
99RPS6KA20.55740461
100DYRK20.55272446
101CAMK2B0.55163970
102RPS6KA30.55067827
103WNK10.54262148
104MAPK120.53047186
105FER0.52655559
106INSRR0.52519817
107CSNK1E0.51119055
108GSK3B0.50139925
109MAPK80.49606762
110MAP3K60.49550897
111PDPK10.49509991
112PRKCZ0.48911060
113ROCK20.48351846
114PRKCE0.47531525
115PRKD10.46309926
116CSNK1G20.45155508
117PDK10.44595230
118PKN10.44256702
119PTK2B0.43577734
120EPHB20.43109664
121CAMK2G0.42501260
122OXSR10.42047022
123FES0.41971517
124ARAF0.41527635
125AKT30.39643433
126PRKD20.38522618
127STK390.38118280
128PRKG10.37149234
129PRKDC0.37123716

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.06045039
2Synaptic vesicle cycle_Homo sapiens_hsa047212.74699667
3Circadian entrainment_Homo sapiens_hsa047132.49458051
4Olfactory transduction_Homo sapiens_hsa047402.40928311
5GABAergic synapse_Homo sapiens_hsa047272.38079328
6Glutamatergic synapse_Homo sapiens_hsa047242.31120900
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.29268891
8Long-term potentiation_Homo sapiens_hsa047202.25423371
9Morphine addiction_Homo sapiens_hsa050322.12092337
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.08470377
11Insulin secretion_Homo sapiens_hsa049112.04170790
12Amphetamine addiction_Homo sapiens_hsa050311.99505157
13Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.98458734
14Salivary secretion_Homo sapiens_hsa049701.93427462
15Dopaminergic synapse_Homo sapiens_hsa047281.85947698
16Gastric acid secretion_Homo sapiens_hsa049711.82933161
17Cardiac muscle contraction_Homo sapiens_hsa042601.80637790
18Cholinergic synapse_Homo sapiens_hsa047251.79108113
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.75275474
20Oxytocin signaling pathway_Homo sapiens_hsa049211.69404706
21Dilated cardiomyopathy_Homo sapiens_hsa054141.66137330
22Taste transduction_Homo sapiens_hsa047421.59869916
23Calcium signaling pathway_Homo sapiens_hsa040201.56000251
24Renin secretion_Homo sapiens_hsa049241.50142253
25Type II diabetes mellitus_Homo sapiens_hsa049301.47660019
26Long-term depression_Homo sapiens_hsa047301.44662723
27GnRH signaling pathway_Homo sapiens_hsa049121.42904078
28Cocaine addiction_Homo sapiens_hsa050301.40143686
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.39652421
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.35965853
31Gap junction_Homo sapiens_hsa045401.32395202
32Serotonergic synapse_Homo sapiens_hsa047261.32340483
33Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.30562640
34cAMP signaling pathway_Homo sapiens_hsa040241.28039485
35Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.27627032
36Arginine and proline metabolism_Homo sapiens_hsa003301.26519865
37cGMP-PKG signaling pathway_Homo sapiens_hsa040221.22217686
38Arginine biosynthesis_Homo sapiens_hsa002201.20504396
39Notch signaling pathway_Homo sapiens_hsa043301.18710571
40Axon guidance_Homo sapiens_hsa043601.18701922
41Phosphatidylinositol signaling system_Homo sapiens_hsa040701.16039324
42Cyanoamino acid metabolism_Homo sapiens_hsa004601.14367646
43Estrogen signaling pathway_Homo sapiens_hsa049151.13008845
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.12536427
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10792377
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.10669955
47Lysine degradation_Homo sapiens_hsa003101.06332263
48Melanogenesis_Homo sapiens_hsa049161.04658509
49Glioma_Homo sapiens_hsa052141.03715664
50ErbB signaling pathway_Homo sapiens_hsa040121.02428472
51Pancreatic secretion_Homo sapiens_hsa049720.99539748
52Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99193602
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.96240922
54Circadian rhythm_Homo sapiens_hsa047100.95723119
55Thyroid hormone signaling pathway_Homo sapiens_hsa049190.92716260
56Dorso-ventral axis formation_Homo sapiens_hsa043200.89765223
57Basal cell carcinoma_Homo sapiens_hsa052170.86227870
58Histidine metabolism_Homo sapiens_hsa003400.84813669
59Glucagon signaling pathway_Homo sapiens_hsa049220.82990805
60Phenylalanine metabolism_Homo sapiens_hsa003600.81743132
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.81105018
62Collecting duct acid secretion_Homo sapiens_hsa049660.80648965
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.79171570
64Endometrial cancer_Homo sapiens_hsa052130.78834704
65Insulin signaling pathway_Homo sapiens_hsa049100.78374943
66Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76982105
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.76407121
68mTOR signaling pathway_Homo sapiens_hsa041500.75990238
69Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75613056
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74830322
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.72828220
72Nitrogen metabolism_Homo sapiens_hsa009100.72085160
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72003005
74MAPK signaling pathway_Homo sapiens_hsa040100.71554443
75VEGF signaling pathway_Homo sapiens_hsa043700.70036327
76Choline metabolism in cancer_Homo sapiens_hsa052310.68537638
77Oocyte meiosis_Homo sapiens_hsa041140.67733895
78Phototransduction_Homo sapiens_hsa047440.67131377
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.67110656
80Adherens junction_Homo sapiens_hsa045200.65195562
81Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63971990
82Thyroid hormone synthesis_Homo sapiens_hsa049180.63971115
83Renal cell carcinoma_Homo sapiens_hsa052110.62351154
84Inositol phosphate metabolism_Homo sapiens_hsa005620.61190599
85Fatty acid metabolism_Homo sapiens_hsa012120.58961963
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58662681
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58176651
88Tight junction_Homo sapiens_hsa045300.56775754
89Rap1 signaling pathway_Homo sapiens_hsa040150.56230637
90Fat digestion and absorption_Homo sapiens_hsa049750.55476204
91Wnt signaling pathway_Homo sapiens_hsa043100.55251346
92Protein digestion and absorption_Homo sapiens_hsa049740.54612732
93Ras signaling pathway_Homo sapiens_hsa040140.53631580
94Vibrio cholerae infection_Homo sapiens_hsa051100.53554812
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53165813
96Mineral absorption_Homo sapiens_hsa049780.52183183
97PPAR signaling pathway_Homo sapiens_hsa033200.51358607
98Non-small cell lung cancer_Homo sapiens_hsa052230.48314283
99Biosynthesis of amino acids_Homo sapiens_hsa012300.48082863
100Alzheimers disease_Homo sapiens_hsa050100.47406984
101Pyruvate metabolism_Homo sapiens_hsa006200.46922201
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45115546
103Carbon metabolism_Homo sapiens_hsa012000.44440017
104Hedgehog signaling pathway_Homo sapiens_hsa043400.43140136
105Bile secretion_Homo sapiens_hsa049760.43087878
106Endocytosis_Homo sapiens_hsa041440.42838258
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42749728
108AMPK signaling pathway_Homo sapiens_hsa041520.42647139
109Insulin resistance_Homo sapiens_hsa049310.42512498
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42282120
111Vitamin B6 metabolism_Homo sapiens_hsa007500.41469126
112Fatty acid biosynthesis_Homo sapiens_hsa000610.41404182
113Prion diseases_Homo sapiens_hsa050200.41363383
114Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41294045
115Fatty acid degradation_Homo sapiens_hsa000710.40190292
116Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40175659
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.40150437
118Central carbon metabolism in cancer_Homo sapiens_hsa052300.39922283
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.39478638
120Fructose and mannose metabolism_Homo sapiens_hsa000510.38707448
121Ovarian steroidogenesis_Homo sapiens_hsa049130.38581687
122Colorectal cancer_Homo sapiens_hsa052100.37899895
123Hippo signaling pathway_Homo sapiens_hsa043900.34255043
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34146679

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