

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.41302461 |
| 2 | chromatin remodeling at centromere (GO:0031055) | 4.76652233 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 4.73332368 |
| 4 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.72455458 |
| 5 | DNA damage response, detection of DNA damage (GO:0042769) | 4.59661818 |
| 6 | establishment of integrated proviral latency (GO:0075713) | 4.59319547 |
| 7 | DNA double-strand break processing (GO:0000729) | 4.55974069 |
| 8 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.43731397 |
| 9 | CENP-A containing nucleosome assembly (GO:0034080) | 4.39695205 |
| 10 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.38454840 |
| 11 | negative regulation of ligase activity (GO:0051352) | 4.38454840 |
| 12 | L-serine metabolic process (GO:0006563) | 4.28671612 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.24438259 |
| 14 | ribosome assembly (GO:0042255) | 4.23907089 |
| 15 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.16165618 |
| 16 | IMP biosynthetic process (GO:0006188) | 4.15515174 |
| 17 | DNA replication checkpoint (GO:0000076) | 4.03233048 |
| 18 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.99513467 |
| 19 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.94027533 |
| 20 | histone exchange (GO:0043486) | 3.90701249 |
| 21 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.80818695 |
| 22 | regulation of helicase activity (GO:0051095) | 3.77626210 |
| 23 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.68047577 |
| 24 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.66888065 |
| 25 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.66888065 |
| 26 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.66888065 |
| 27 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.65261873 |
| 28 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.65261873 |
| 29 | establishment of viral latency (GO:0019043) | 3.64516195 |
| 30 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.63614740 |
| 31 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.63614740 |
| 32 | mitotic metaphase plate congression (GO:0007080) | 3.63514469 |
| 33 | purine nucleobase biosynthetic process (GO:0009113) | 3.63310491 |
| 34 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.59868144 |
| 35 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.59466712 |
| 36 | DNA strand elongation (GO:0022616) | 3.58131537 |
| 37 | DNA replication-independent nucleosome organization (GO:0034724) | 3.58054682 |
| 38 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.58054682 |
| 39 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.54549337 |
| 40 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.54160456 |
| 41 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.53997673 |
| 42 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.53997673 |
| 43 | IMP metabolic process (GO:0046040) | 3.53691954 |
| 44 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.53508629 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.53508629 |
| 46 | rRNA modification (GO:0000154) | 3.51523218 |
| 47 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.49753171 |
| 48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.48513939 |
| 49 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.44085022 |
| 50 | negative regulation of sister chromatid segregation (GO:0033046) | 3.44085022 |
| 51 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.44085022 |
| 52 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.44085022 |
| 53 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.44085022 |
| 54 | positive regulation of ligase activity (GO:0051351) | 3.42609064 |
| 55 | regulation of ligase activity (GO:0051340) | 3.40442243 |
| 56 | negative regulation of chromosome segregation (GO:0051985) | 3.36449558 |
| 57 | protein neddylation (GO:0045116) | 3.28448452 |
| 58 | spliceosomal snRNP assembly (GO:0000387) | 3.25534987 |
| 59 | nucleobase biosynthetic process (GO:0046112) | 3.23954593 |
| 60 | mitotic spindle checkpoint (GO:0071174) | 3.23859134 |
| 61 | spindle checkpoint (GO:0031577) | 3.23514828 |
| 62 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.22401609 |
| 63 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.21795531 |
| 64 | cullin deneddylation (GO:0010388) | 3.20677547 |
| 65 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.17124849 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 3.17124849 |
| 67 | nodal signaling pathway (GO:0038092) | 3.15575970 |
| 68 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.13857356 |
| 69 | heterochromatin organization (GO:0070828) | 3.11790760 |
| 70 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.10751972 |
| 71 | primitive streak formation (GO:0090009) | 3.10148065 |
| 72 | cell cycle G1/S phase transition (GO:0044843) | 3.08061067 |
| 73 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.08061067 |
| 74 | protein localization to kinetochore (GO:0034501) | 3.06351028 |
| 75 | protein deneddylation (GO:0000338) | 3.04110231 |
| 76 | female gonad development (GO:0008585) | 3.03188270 |
| 77 | mitotic spindle assembly checkpoint (GO:0007094) | 3.02606326 |
| 78 | negative regulation of protein ubiquitination (GO:0031397) | 3.02410980 |
| 79 | metaphase plate congression (GO:0051310) | 3.01544246 |
| 80 | protein maturation by protein folding (GO:0022417) | 3.00591048 |
| 81 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.99973229 |
| 82 | transcription from mitochondrial promoter (GO:0006390) | 2.96795446 |
| 83 | pseudouridine synthesis (GO:0001522) | 2.96685256 |
| 84 | histone mRNA metabolic process (GO:0008334) | 2.95895434 |
| 85 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.95519357 |
| 86 | non-recombinational repair (GO:0000726) | 2.95519357 |
| 87 | tRNA aminoacylation for protein translation (GO:0006418) | 2.94633926 |
| 88 | spindle assembly checkpoint (GO:0071173) | 2.94584642 |
| 89 | protein targeting to mitochondrion (GO:0006626) | 2.94447898 |
| 90 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.94071769 |
| 91 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.94071769 |
| 92 | negative regulation of mitosis (GO:0045839) | 2.92630146 |
| 93 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.92206150 |
| 94 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.92206150 |
| 95 | formation of translation preinitiation complex (GO:0001731) | 2.90034490 |
| 96 | DNA unwinding involved in DNA replication (GO:0006268) | 2.89646794 |
| 97 | regulation of cellular amine metabolic process (GO:0033238) | 2.89401738 |
| 98 | tRNA aminoacylation (GO:0043039) | 2.88581651 |
| 99 | amino acid activation (GO:0043038) | 2.88581651 |
| 100 | oxidative phosphorylation (GO:0006119) | 2.86984918 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.46159905 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.88792922 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.72022249 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.71286562 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.59600669 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.40704619 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.21920999 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.91384607 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.88942576 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.87056469 |
| 11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.63590881 |
| 12 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.57950261 |
| 13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.52041370 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.47833075 |
| 15 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.47412002 |
| 16 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.47412002 |
| 17 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.47412002 |
| 18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.39566669 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.39446858 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.38590097 |
| 21 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.24434497 |
| 22 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.23166176 |
| 23 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.18294336 |
| 24 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 2.16923931 |
| 25 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.12370851 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09905889 |
| 27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.04374588 |
| 28 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.02209476 |
| 29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.97736012 |
| 30 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.95518952 |
| 31 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.94493877 |
| 32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.92016697 |
| 33 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.90517772 |
| 34 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.89796360 |
| 35 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.89224456 |
| 36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.89026860 |
| 37 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.88896365 |
| 38 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.88149949 |
| 39 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.87338453 |
| 40 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.87241515 |
| 41 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.83685724 |
| 42 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.81806538 |
| 43 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.76673749 |
| 44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.74760447 |
| 45 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.74097310 |
| 46 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.70061819 |
| 47 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.69870020 |
| 48 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.65036781 |
| 49 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.63464814 |
| 50 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.61579538 |
| 51 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.58970974 |
| 52 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.58348444 |
| 53 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.55256159 |
| 54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.52643336 |
| 55 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.50611808 |
| 56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.50574179 |
| 57 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.47932696 |
| 58 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.46370667 |
| 59 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.45212997 |
| 60 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.42684060 |
| 61 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.39959733 |
| 62 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.37358628 |
| 63 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.36302271 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.34623372 |
| 65 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.33023034 |
| 66 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.32856028 |
| 67 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.31841221 |
| 68 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.31639903 |
| 69 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.25594937 |
| 70 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.25130191 |
| 71 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.24264341 |
| 72 | EWS_26573619_Chip-Seq_HEK293_Human | 1.24216505 |
| 73 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.23371264 |
| 74 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.21007698 |
| 75 | VDR_22108803_ChIP-Seq_LS180_Human | 1.18652588 |
| 76 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.17582489 |
| 77 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.07443562 |
| 78 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.05844391 |
| 79 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.03106664 |
| 80 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.01889466 |
| 81 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.00238698 |
| 82 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.97685475 |
| 83 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.95921231 |
| 84 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.94995872 |
| 85 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93847965 |
| 86 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.92396708 |
| 87 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.91731307 |
| 88 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.90987533 |
| 89 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.89215585 |
| 90 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.88531249 |
| 91 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.86222494 |
| 92 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83137049 |
| 93 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.83017878 |
| 94 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.82540049 |
| 95 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 0.82426108 |
| 96 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.81559520 |
| 97 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.80490448 |
| 98 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.79531066 |
| 99 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.78172513 |
| 100 | EOMES_21245162_ChIP-Seq_HESCs_Human | 0.76404950 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.36101365 |
| 2 | MP0008058_abnormal_DNA_repair | 4.05091851 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 3.94490751 |
| 4 | MP0003890_abnormal_embryonic-extraembry | 3.93159401 |
| 5 | MP0010094_abnormal_chromosome_stability | 3.48916455 |
| 6 | MP0008877_abnormal_DNA_methylation | 3.37766227 |
| 7 | MP0003111_abnormal_nucleus_morphology | 3.17455982 |
| 8 | MP0008057_abnormal_DNA_replication | 3.05808806 |
| 9 | MP0002254_reproductive_system_inflammat | 3.03469338 |
| 10 | MP0003941_abnormal_skin_development | 3.00485759 |
| 11 | MP0003077_abnormal_cell_cycle | 2.78558486 |
| 12 | MP0008932_abnormal_embryonic_tissue | 2.75535428 |
| 13 | MP0001188_hyperpigmentation | 2.62125027 |
| 14 | MP0006292_abnormal_olfactory_placode | 2.61787598 |
| 15 | MP0004133_heterotaxia | 2.30924874 |
| 16 | MP0003567_abnormal_fetal_cardiomyocyte | 2.25589487 |
| 17 | MP0003718_maternal_effect | 2.14153402 |
| 18 | MP0001730_embryonic_growth_arrest | 2.09697792 |
| 19 | MP0008007_abnormal_cellular_replicative | 2.02731552 |
| 20 | MP0009672_abnormal_birth_weight | 1.98024855 |
| 21 | MP0003119_abnormal_digestive_system | 1.94266377 |
| 22 | MP0010352_gastrointestinal_tract_polyps | 1.86513343 |
| 23 | MP0003806_abnormal_nucleotide_metabolis | 1.77828941 |
| 24 | MP0010030_abnormal_orbit_morphology | 1.72902887 |
| 25 | MP0003121_genomic_imprinting | 1.72394031 |
| 26 | MP0001293_anophthalmia | 1.66607292 |
| 27 | MP0000350_abnormal_cell_proliferation | 1.59167409 |
| 28 | MP0002163_abnormal_gland_morphology | 1.58998047 |
| 29 | MP0003186_abnormal_redox_activity | 1.56908580 |
| 30 | MP0003123_paternal_imprinting | 1.54232767 |
| 31 | MP0002102_abnormal_ear_morphology | 1.49501195 |
| 32 | MP0002736_abnormal_nociception_after | 1.45914136 |
| 33 | MP0002084_abnormal_developmental_patter | 1.43168756 |
| 34 | MP0003136_yellow_coat_color | 1.42830856 |
| 35 | MP0006035_abnormal_mitochondrial_morpho | 1.42652627 |
| 36 | MP0001672_abnormal_embryogenesis/_devel | 1.40035274 |
| 37 | MP0005380_embryogenesis_phenotype | 1.40035274 |
| 38 | MP0003787_abnormal_imprinting | 1.39822433 |
| 39 | MP0005084_abnormal_gallbladder_morpholo | 1.38291699 |
| 40 | MP0008789_abnormal_olfactory_epithelium | 1.37243927 |
| 41 | MP0003937_abnormal_limbs/digits/tail_de | 1.35150036 |
| 42 | MP0002085_abnormal_embryonic_tissue | 1.33369895 |
| 43 | MP0003786_premature_aging | 1.30655423 |
| 44 | MP0010307_abnormal_tumor_latency | 1.26657454 |
| 45 | MP0001697_abnormal_embryo_size | 1.26583287 |
| 46 | MP0003122_maternal_imprinting | 1.25893377 |
| 47 | MP0002751_abnormal_autonomic_nervous | 1.25384831 |
| 48 | MP0005499_abnormal_olfactory_system | 1.23779154 |
| 49 | MP0005394_taste/olfaction_phenotype | 1.23779154 |
| 50 | MP0001529_abnormal_vocalization | 1.20013475 |
| 51 | MP0003011_delayed_dark_adaptation | 1.15609206 |
| 52 | MP0002080_prenatal_lethality | 1.14492139 |
| 53 | MP0006036_abnormal_mitochondrial_physio | 1.14478831 |
| 54 | MP0005670_abnormal_white_adipose | 1.10424620 |
| 55 | MP0004147_increased_porphyrin_level | 1.07182628 |
| 56 | MP0009697_abnormal_copulation | 1.05243813 |
| 57 | MP0003195_calcinosis | 1.04504688 |
| 58 | MP0003984_embryonic_growth_retardation | 1.03523372 |
| 59 | MP0002210_abnormal_sex_determination | 1.02873362 |
| 60 | MP0001286_abnormal_eye_development | 1.02349342 |
| 61 | MP0001177_atelectasis | 1.01122164 |
| 62 | MP0001485_abnormal_pinna_reflex | 1.00454970 |
| 63 | MP0002088_abnormal_embryonic_growth/wei | 1.00412446 |
| 64 | MP0009703_decreased_birth_body | 0.98991966 |
| 65 | MP0004197_abnormal_fetal_growth/weight/ | 0.97439162 |
| 66 | MP0001929_abnormal_gametogenesis | 0.96099362 |
| 67 | MP0005075_abnormal_melanosome_morpholog | 0.94854701 |
| 68 | MP0000049_abnormal_middle_ear | 0.94287363 |
| 69 | MP0001145_abnormal_male_reproductive | 0.92226382 |
| 70 | MP0002111_abnormal_tail_morphology | 0.91410338 |
| 71 | MP0000653_abnormal_sex_gland | 0.90600948 |
| 72 | MP0000313_abnormal_cell_death | 0.90190447 |
| 73 | MP0008872_abnormal_physiological_respon | 0.89504534 |
| 74 | MP0002233_abnormal_nose_morphology | 0.85666663 |
| 75 | MP0002697_abnormal_eye_size | 0.85197143 |
| 76 | MP0002086_abnormal_extraembryonic_tissu | 0.84072176 |
| 77 | MP0000537_abnormal_urethra_morphology | 0.83780099 |
| 78 | MP0002938_white_spotting | 0.80542632 |
| 79 | MP0002160_abnormal_reproductive_system | 0.78777729 |
| 80 | MP0005379_endocrine/exocrine_gland_phen | 0.78725346 |
| 81 | MP0000490_abnormal_crypts_of | 0.78401661 |
| 82 | MP0000372_irregular_coat_pigmentation | 0.75352531 |
| 83 | MP0002796_impaired_skin_barrier | 0.74431152 |
| 84 | MP0005647_abnormal_sex_gland | 0.73153719 |
| 85 | MP0006054_spinal_hemorrhage | 0.72663934 |
| 86 | MP0004215_abnormal_myocardial_fiber | 0.72467728 |
| 87 | MP0006072_abnormal_retinal_apoptosis | 0.72271996 |
| 88 | MP0003137_abnormal_impulse_conducting | 0.71416173 |
| 89 | MP0003221_abnormal_cardiomyocyte_apopto | 0.71043446 |
| 90 | MP0003880_abnormal_central_pattern | 0.70456093 |
| 91 | MP0008770_decreased_survivor_rate | 0.69936224 |
| 92 | MP0001119_abnormal_female_reproductive | 0.65999277 |
| 93 | MP0000358_abnormal_cell_content/ | 0.65487756 |
| 94 | MP0005395_other_phenotype | 0.65314134 |
| 95 | MP0005646_abnormal_pituitary_gland | 0.63256225 |
| 96 | MP0000428_abnormal_craniofacial_morphol | 0.63106854 |
| 97 | MP0001764_abnormal_homeostasis | 0.61058957 |
| 98 | MP0000579_abnormal_nail_morphology | 0.59559769 |
| 99 | MP0003861_abnormal_nervous_system | 0.59529132 |
| 100 | MP0003698_abnormal_male_reproductive | 0.59071212 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 5.33391836 |
| 2 | Colon cancer (HP:0003003) | 4.51102604 |
| 3 | Ependymoma (HP:0002888) | 3.64192595 |
| 4 | Multiple enchondromatosis (HP:0005701) | 3.45092875 |
| 5 | Meckel diverticulum (HP:0002245) | 3.38057557 |
| 6 | Abnormality of abdominal situs (HP:0011620) | 3.36612291 |
| 7 | Abdominal situs inversus (HP:0003363) | 3.36612291 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.18185316 |
| 9 | Abnormality of the ileum (HP:0001549) | 3.16505717 |
| 10 | Birth length less than 3rd percentile (HP:0003561) | 3.06568876 |
| 11 | Abnormality of the preputium (HP:0100587) | 3.05859404 |
| 12 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.03566972 |
| 13 | Abnormality of chromosome stability (HP:0003220) | 3.02149616 |
| 14 | Hyperglycinemia (HP:0002154) | 2.98267926 |
| 15 | Acute encephalopathy (HP:0006846) | 2.97663082 |
| 16 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.89131947 |
| 17 | Agnosia (HP:0010524) | 2.79676705 |
| 18 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.76659608 |
| 19 | Abnormality of glycine metabolism (HP:0010895) | 2.74979732 |
| 20 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.74979732 |
| 21 | Chromsome breakage (HP:0040012) | 2.74748925 |
| 22 | Abnormality of serum amino acid levels (HP:0003112) | 2.68575349 |
| 23 | Increased CSF lactate (HP:0002490) | 2.66346559 |
| 24 | Spastic diplegia (HP:0001264) | 2.57055259 |
| 25 | Septo-optic dysplasia (HP:0100842) | 2.56520536 |
| 26 | Microvesicular hepatic steatosis (HP:0001414) | 2.56195344 |
| 27 | Stenosis of the external auditory canal (HP:0000402) | 2.56080606 |
| 28 | Abnormality of the astrocytes (HP:0100707) | 2.49047236 |
| 29 | Astrocytoma (HP:0009592) | 2.49047236 |
| 30 | Absent radius (HP:0003974) | 2.46343392 |
| 31 | Progressive macrocephaly (HP:0004481) | 2.45819711 |
| 32 | Glioma (HP:0009733) | 2.44254686 |
| 33 | Horseshoe kidney (HP:0000085) | 2.44189592 |
| 34 | Aplasia involving forearm bones (HP:0009822) | 2.43162592 |
| 35 | Absent forearm bone (HP:0003953) | 2.43162592 |
| 36 | Rhabdomyosarcoma (HP:0002859) | 2.42107549 |
| 37 | Abnormal hair whorl (HP:0010721) | 2.41530653 |
| 38 | Hyperglycinuria (HP:0003108) | 2.39564741 |
| 39 | Cerebral edema (HP:0002181) | 2.38804778 |
| 40 | Mitochondrial inheritance (HP:0001427) | 2.36814793 |
| 41 | Neoplasm of the adrenal gland (HP:0100631) | 2.31993787 |
| 42 | Small intestinal stenosis (HP:0012848) | 2.26971333 |
| 43 | Duodenal stenosis (HP:0100867) | 2.26971333 |
| 44 | Increased hepatocellular lipid droplets (HP:0006565) | 2.25388835 |
| 45 | Fused cervical vertebrae (HP:0002949) | 2.23627992 |
| 46 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.22129974 |
| 47 | Increased serum lactate (HP:0002151) | 2.19409432 |
| 48 | Type I transferrin isoform profile (HP:0003642) | 2.16889710 |
| 49 | Increased serum pyruvate (HP:0003542) | 2.16162886 |
| 50 | Medulloblastoma (HP:0002885) | 2.16092297 |
| 51 | Embryonal renal neoplasm (HP:0011794) | 2.14622277 |
| 52 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.13748946 |
| 53 | Abnormality of alanine metabolism (HP:0010916) | 2.13748946 |
| 54 | Hyperalaninemia (HP:0003348) | 2.13748946 |
| 55 | Abnormal lung lobation (HP:0002101) | 2.12156839 |
| 56 | Methylmalonic aciduria (HP:0012120) | 2.09428994 |
| 57 | Bilateral microphthalmos (HP:0007633) | 2.08073711 |
| 58 | Abnormality of the duodenum (HP:0002246) | 2.07982215 |
| 59 | Methylmalonic acidemia (HP:0002912) | 2.07550091 |
| 60 | Abnormality of the septum pellucidum (HP:0007375) | 2.05164145 |
| 61 | Triphalangeal thumb (HP:0001199) | 2.03256004 |
| 62 | Absent septum pellucidum (HP:0001331) | 2.02374765 |
| 63 | Hypoglycemic seizures (HP:0002173) | 2.01712877 |
| 64 | Supernumerary spleens (HP:0009799) | 2.01360150 |
| 65 | Hepatocellular necrosis (HP:0001404) | 1.99627326 |
| 66 | Carpal bone hypoplasia (HP:0001498) | 1.99389918 |
| 67 | Lactic acidosis (HP:0003128) | 1.98862495 |
| 68 | Respiratory difficulties (HP:0002880) | 1.98077109 |
| 69 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.96881815 |
| 70 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.96881815 |
| 71 | Single umbilical artery (HP:0001195) | 1.96881815 |
| 72 | Lipid accumulation in hepatocytes (HP:0006561) | 1.96352567 |
| 73 | Cerebral hypomyelination (HP:0006808) | 1.94709900 |
| 74 | Abnormality of methionine metabolism (HP:0010901) | 1.94036597 |
| 75 | Ectopic kidney (HP:0000086) | 1.93524285 |
| 76 | Clubbing of toes (HP:0100760) | 1.91046883 |
| 77 | Cortical dysplasia (HP:0002539) | 1.90165026 |
| 78 | Abnormality of the umbilical cord (HP:0010881) | 1.89923152 |
| 79 | Reticulocytopenia (HP:0001896) | 1.89284325 |
| 80 | Nasal speech (HP:0001611) | 1.88418244 |
| 81 | Neoplasm of the colon (HP:0100273) | 1.87218424 |
| 82 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.86628850 |
| 83 | Abnormality of glycolysis (HP:0004366) | 1.84793831 |
| 84 | Anal atresia (HP:0002023) | 1.84548428 |
| 85 | Hepatic necrosis (HP:0002605) | 1.82653670 |
| 86 | Abnormality of the clitoris (HP:0000056) | 1.82403713 |
| 87 | Reduced antithrombin III activity (HP:0001976) | 1.80383369 |
| 88 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.80180341 |
| 89 | Gonadotropin excess (HP:0000837) | 1.79711222 |
| 90 | Hypoglycemic coma (HP:0001325) | 1.78831736 |
| 91 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.78383775 |
| 92 | Decreased muscle mass (HP:0003199) | 1.77574705 |
| 93 | Leukodystrophy (HP:0002415) | 1.75524773 |
| 94 | Breast carcinoma (HP:0003002) | 1.75376203 |
| 95 | Postnatal microcephaly (HP:0005484) | 1.74988912 |
| 96 | Generalized hypotonia (HP:0001290) | 1.74877822 |
| 97 | Aqueductal stenosis (HP:0002410) | 1.73144293 |
| 98 | Biliary tract neoplasm (HP:0100574) | 1.71902981 |
| 99 | Cellular immunodeficiency (HP:0005374) | 1.71234350 |
| 100 | Hypoplastic female external genitalia (HP:0012815) | 1.70691242 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 3.99494863 |
| 2 | BUB1 | 3.96302682 |
| 3 | PBK | 3.36923455 |
| 4 | VRK2 | 3.22706293 |
| 5 | CDC7 | 3.06792726 |
| 6 | STK16 | 3.02135276 |
| 7 | TTK | 2.98285507 |
| 8 | SRPK1 | 2.93750518 |
| 9 | MKNK2 | 2.78777692 |
| 10 | MST4 | 2.62535385 |
| 11 | WNK3 | 2.55914267 |
| 12 | PLK3 | 2.50554542 |
| 13 | MKNK1 | 2.41580708 |
| 14 | ZAK | 2.24539075 |
| 15 | TAF1 | 2.21953006 |
| 16 | BRSK2 | 2.21695733 |
| 17 | TNIK | 2.00336462 |
| 18 | PDK2 | 1.93746182 |
| 19 | NME1 | 1.90464564 |
| 20 | EIF2AK3 | 1.87654925 |
| 21 | VRK1 | 1.86508386 |
| 22 | PLK4 | 1.76538645 |
| 23 | NEK1 | 1.67519898 |
| 24 | TRIM28 | 1.66482677 |
| 25 | PLK1 | 1.57711779 |
| 26 | ACVR1B | 1.56056158 |
| 27 | DYRK2 | 1.52848030 |
| 28 | NUAK1 | 1.34824640 |
| 29 | PASK | 1.34356944 |
| 30 | BRSK1 | 1.33955716 |
| 31 | CDK19 | 1.29230454 |
| 32 | NLK | 1.27361252 |
| 33 | WEE1 | 1.25197267 |
| 34 | NME2 | 1.23670281 |
| 35 | DYRK3 | 1.17843872 |
| 36 | OXSR1 | 1.10431734 |
| 37 | EIF2AK1 | 1.08926038 |
| 38 | ATR | 1.08688075 |
| 39 | WNK4 | 1.02571440 |
| 40 | ALK | 0.97829746 |
| 41 | STK39 | 0.91709635 |
| 42 | EIF2AK2 | 0.89212282 |
| 43 | STK4 | 0.85034841 |
| 44 | CHEK2 | 0.84722629 |
| 45 | PLK2 | 0.81572374 |
| 46 | KDR | 0.79221563 |
| 47 | FGFR1 | 0.77601176 |
| 48 | BMPR1B | 0.75211375 |
| 49 | PAK4 | 0.73890790 |
| 50 | CSNK1G1 | 0.73713071 |
| 51 | MAP3K8 | 0.70376011 |
| 52 | AURKB | 0.70264640 |
| 53 | BCKDK | 0.69326273 |
| 54 | BCR | 0.68643790 |
| 55 | ATM | 0.67860512 |
| 56 | TGFBR1 | 0.64433547 |
| 57 | TESK2 | 0.61873109 |
| 58 | DAPK1 | 0.61582565 |
| 59 | ERBB4 | 0.60221299 |
| 60 | GRK1 | 0.58724406 |
| 61 | CASK | 0.58459178 |
| 62 | PNCK | 0.57816095 |
| 63 | STK38L | 0.56496938 |
| 64 | CSNK1G2 | 0.55777425 |
| 65 | MAP3K4 | 0.55564473 |
| 66 | CHEK1 | 0.55045165 |
| 67 | CSNK2A1 | 0.53972499 |
| 68 | TIE1 | 0.53847482 |
| 69 | MAP3K10 | 0.53042454 |
| 70 | MELK | 0.51631395 |
| 71 | STK3 | 0.50783271 |
| 72 | CSNK1G3 | 0.50323173 |
| 73 | CSNK1E | 0.49542323 |
| 74 | MINK1 | 0.45579413 |
| 75 | CSNK2A2 | 0.42970691 |
| 76 | LATS2 | 0.42838308 |
| 77 | ERBB3 | 0.41971416 |
| 78 | CDK7 | 0.39244692 |
| 79 | BRAF | 0.37130657 |
| 80 | AURKA | 0.36896505 |
| 81 | UHMK1 | 0.35102205 |
| 82 | EGFR | 0.34010952 |
| 83 | STK10 | 0.33576897 |
| 84 | CDK2 | 0.32285214 |
| 85 | CDK1 | 0.32130495 |
| 86 | PRKCI | 0.31179644 |
| 87 | RPS6KA4 | 0.30347818 |
| 88 | CDK9 | 0.30066476 |
| 89 | PRKDC | 0.29999591 |
| 90 | BMX | 0.29328097 |
| 91 | EPHA4 | 0.28628830 |
| 92 | PAK1 | 0.28394533 |
| 93 | PRKCG | 0.26837171 |
| 94 | NEK2 | 0.26800369 |
| 95 | CSNK1A1L | 0.26588282 |
| 96 | MAP3K5 | 0.26251558 |
| 97 | DYRK1A | 0.25999926 |
| 98 | INSRR | 0.24781575 |
| 99 | RPS6KA5 | 0.23907096 |
| 100 | MAP4K2 | 0.23731728 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.39652760 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.38771916 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.38359911 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.28379737 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.78841908 |
| 6 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.57716958 |
| 7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.47874580 |
| 8 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.42382737 |
| 9 | Base excision repair_Homo sapiens_hsa03410 | 2.31186534 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.30115573 |
| 11 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.20954131 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.18982432 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 2.01668491 |
| 14 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.99267993 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.93477138 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.90861022 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.90396428 |
| 18 | Ribosome_Homo sapiens_hsa03010 | 1.88614450 |
| 19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.87004344 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.86590865 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.77828484 |
| 22 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.76846606 |
| 23 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.75217959 |
| 24 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.75060222 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.75035604 |
| 26 | Cell cycle_Homo sapiens_hsa04110 | 1.73146085 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.70429876 |
| 28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.60503725 |
| 29 | Huntingtons disease_Homo sapiens_hsa05016 | 1.58068270 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.55736682 |
| 31 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.48766194 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.44781469 |
| 33 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.41989330 |
| 34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.37462208 |
| 35 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.37231118 |
| 36 | Carbon metabolism_Homo sapiens_hsa01200 | 1.36878028 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.35594426 |
| 38 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.31111834 |
| 39 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.23571216 |
| 40 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.23085453 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.21909914 |
| 42 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.14997510 |
| 43 | Alzheimers disease_Homo sapiens_hsa05010 | 1.11625859 |
| 44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.91935000 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.91076079 |
| 46 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.89600947 |
| 47 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.86040716 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 0.82524106 |
| 49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80886184 |
| 50 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.79371363 |
| 51 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.72556433 |
| 52 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.69029448 |
| 53 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66663115 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66330084 |
| 55 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.65320670 |
| 56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.65025319 |
| 57 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.63754320 |
| 58 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.63240570 |
| 59 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.60356156 |
| 60 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.59828883 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58771422 |
| 62 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.56339184 |
| 63 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.52199132 |
| 64 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.51043211 |
| 65 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.49451017 |
| 66 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.48694227 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.47563604 |
| 68 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.46697960 |
| 69 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.45678550 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45548493 |
| 71 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.44854917 |
| 72 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.44850761 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.44057881 |
| 74 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.39663535 |
| 75 | Tight junction_Homo sapiens_hsa04530 | 0.35420757 |
| 76 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.31580824 |
| 77 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29881122 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.28626434 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.27696011 |
| 80 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.26974932 |
| 81 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.26892467 |
| 82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26815801 |
| 83 | Sulfur relay system_Homo sapiens_hsa04122 | 0.26704745 |
| 84 | Galactose metabolism_Homo sapiens_hsa00052 | 0.24667007 |
| 85 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.23321265 |
| 86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.21476820 |
| 87 | Lysine degradation_Homo sapiens_hsa00310 | 0.20130244 |
| 88 | Adherens junction_Homo sapiens_hsa04520 | 0.19249252 |
| 89 | Thyroid cancer_Homo sapiens_hsa05216 | 0.18749713 |
| 90 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.16184335 |
| 91 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.15989481 |
| 92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.15595546 |
| 93 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.15443626 |
| 94 | Histidine metabolism_Homo sapiens_hsa00340 | 0.15367783 |
| 95 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.15292552 |
| 96 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.14815327 |
| 97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.14765819 |
| 98 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.13729090 |
| 99 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.10912381 |
| 100 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.08544233 |

