WSCD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)9.76659612
2axon ensheathment in central nervous system (GO:0032291)9.76659612
3postsynaptic membrane organization (GO:0001941)6.68695158
4myelination (GO:0042552)5.59255850
5ensheathment of neurons (GO:0007272)5.56690677
6axon ensheathment (GO:0008366)5.56690677
7fatty acid elongation (GO:0030497)5.38084449
8pyrimidine nucleobase catabolic process (GO:0006208)4.66112859
9long-chain fatty acid biosynthetic process (GO:0042759)4.58291276
10L-amino acid import (GO:0043092)4.46145017
11myelin maintenance (GO:0043217)4.30875050
12neuron cell-cell adhesion (GO:0007158)4.20208063
13establishment of mitochondrion localization (GO:0051654)4.19086417
14negative regulation of neurotransmitter transport (GO:0051589)4.13914592
15oligodendrocyte differentiation (GO:0048709)4.13601949
16eye photoreceptor cell differentiation (GO:0001754)4.01507468
17photoreceptor cell differentiation (GO:0046530)4.01507468
18presynaptic membrane organization (GO:0097090)3.96586643
19negative regulation of neurotransmitter secretion (GO:0046929)3.95371558
20apical protein localization (GO:0045176)3.89436242
21negative regulation of protein localization to cell surface (GO:2000009)3.83450256
22presynaptic membrane assembly (GO:0097105)3.71019964
23synaptic vesicle maturation (GO:0016188)3.69677087
24asymmetric protein localization (GO:0008105)3.62379759
25amino acid import (GO:0043090)3.61471286
26positive regulation of oligodendrocyte differentiation (GO:0048714)3.59382561
27transmission of nerve impulse (GO:0019226)3.57275986
28nucleobase catabolic process (GO:0046113)3.55897496
29adult walking behavior (GO:0007628)3.52461830
30creatine metabolic process (GO:0006600)3.51987111
31regulation of collateral sprouting (GO:0048670)3.44826940
32astrocyte development (GO:0014002)3.44385476
33neuronal action potential propagation (GO:0019227)3.41509103
34mechanosensory behavior (GO:0007638)3.40924707
35response to methylmercury (GO:0051597)3.39179045
36neuronal stem cell maintenance (GO:0097150)3.36342260
37neurotransmitter-gated ion channel clustering (GO:0072578)3.28560340
38dendritic spine morphogenesis (GO:0060997)3.27194426
39peptidyl-tyrosine autophosphorylation (GO:0038083)3.25916289
40synaptic vesicle exocytosis (GO:0016079)3.24522375
41regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.23328331
42neuron recognition (GO:0008038)3.22500774
43camera-type eye morphogenesis (GO:0048593)3.21312055
44negative regulation of axonogenesis (GO:0050771)3.16618172
45regulation of synapse structural plasticity (GO:0051823)3.16523486
46cerebral cortex radially oriented cell migration (GO:0021799)3.15046754
47positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.14584019
48substantia nigra development (GO:0021762)3.11722437
49glycerophospholipid catabolic process (GO:0046475)3.10555985
50locomotory exploration behavior (GO:0035641)3.08663852
51positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.06915361
52glycine transport (GO:0015816)3.06870323
53paraxial mesoderm development (GO:0048339)3.06787256
54exploration behavior (GO:0035640)3.04198593
55neuronal ion channel clustering (GO:0045161)3.03948985
56spinal cord development (GO:0021510)3.03341475
57cholesterol biosynthetic process (GO:0006695)3.01597324
58peripheral nervous system axon ensheathment (GO:0032292)3.00757425
59myelination in peripheral nervous system (GO:0022011)3.00757425
60negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.00739058
61ionotropic glutamate receptor signaling pathway (GO:0035235)3.00587941
62regulation of glutamate receptor signaling pathway (GO:1900449)2.98804527
63astrocyte differentiation (GO:0048708)2.96702494
64axonal fasciculation (GO:0007413)2.95097838
65regulation of synaptic vesicle exocytosis (GO:2000300)2.94490486
66dendrite morphogenesis (GO:0048813)2.92872059
67cerebellar granule cell differentiation (GO:0021707)2.92052468
68positive regulation of synapse assembly (GO:0051965)2.91304108
69negative regulation of axon extension (GO:0030517)2.90506194
70dermatan sulfate biosynthetic process (GO:0030208)2.89540560
71protein localization to synapse (GO:0035418)2.88393273
72regulation of short-term neuronal synaptic plasticity (GO:0048172)2.87706755
73membrane assembly (GO:0071709)2.86430387
74mating behavior (GO:0007617)2.86348663
75calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.86002352
76neuron remodeling (GO:0016322)2.85019349
77cellular potassium ion homeostasis (GO:0030007)2.84948305
78regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.83884119
79glutamate receptor signaling pathway (GO:0007215)2.83799358
80synapse assembly (GO:0007416)2.83455294
81membrane tubulation (GO:0097320)2.82185333
82substrate-independent telencephalic tangential migration (GO:0021826)2.80906634
83substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.80906634
84gamma-aminobutyric acid signaling pathway (GO:0007214)2.80047532
85vocalization behavior (GO:0071625)2.78598400
86glutamate secretion (GO:0014047)2.78222515
87neurotransmitter uptake (GO:0001504)2.77500511
88establishment of nucleus localization (GO:0040023)2.75255912
89central nervous system projection neuron axonogenesis (GO:0021952)2.74971125
90long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.74669945
91cell migration in hindbrain (GO:0021535)2.74491724
92gamma-aminobutyric acid transport (GO:0015812)2.73662641
93cellular response to cholesterol (GO:0071397)2.72300001
94establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.71675307
95mitochondrion transport along microtubule (GO:0047497)2.71675307
96regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.71454709
97nerve growth factor signaling pathway (GO:0038180)2.70159063
98response to redox state (GO:0051775)2.70072491
99sodium ion export (GO:0071436)2.69800583
100protein palmitoylation (GO:0018345)2.69765925
101import into cell (GO:0098657)2.67977862
102regulation of neuronal synaptic plasticity (GO:0048168)2.67943741
103potassium ion homeostasis (GO:0055075)2.67803817
104layer formation in cerebral cortex (GO:0021819)2.66689909
105positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.66263172
106synaptic transmission, glutamatergic (GO:0035249)2.66137557
107positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.65753930
108limb bud formation (GO:0060174)2.65055835
109sterol biosynthetic process (GO:0016126)2.64583677
110response to auditory stimulus (GO:0010996)2.64363315
111cell communication by electrical coupling (GO:0010644)2.62985262
112axon development (GO:0061564)2.62336418
113lateral sprouting from an epithelium (GO:0060601)2.62091174
114potassium ion import (GO:0010107)2.61955916
115cerebral cortex cell migration (GO:0021795)2.61802218
116negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.61102628
117neuron-neuron synaptic transmission (GO:0007270)2.60654908
118negative regulation of oligodendrocyte differentiation (GO:0048715)2.60237681
119regulation of somitogenesis (GO:0014807)2.60101775
120regulation of respiratory system process (GO:0044065)2.60085076
121G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.59923117
122glial cell differentiation (GO:0010001)2.59048564
123axon extension (GO:0048675)2.58954783
124regulation of axon extension involved in axon guidance (GO:0048841)2.58399916
125olfactory bulb development (GO:0021772)2.58099107
126negative regulation of synaptic transmission, GABAergic (GO:0032229)2.57300965
127adult locomotory behavior (GO:0008344)2.56547874
128dermatan sulfate metabolic process (GO:0030205)2.55968666
129neuroblast proliferation (GO:0007405)2.54058436
130long-term memory (GO:0007616)2.53448807
131heart valve formation (GO:0003188)2.52685371
132auditory behavior (GO:0031223)2.52135619
133long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.50917518
134regulation of dopamine metabolic process (GO:0042053)2.50264523
135regulation of catecholamine metabolic process (GO:0042069)2.50264523
136response to lipoprotein particle (GO:0055094)2.49777976
137membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.49359509
138positive regulation of glial cell differentiation (GO:0045687)2.48565878
139regulation of axon guidance (GO:1902667)2.46243035
140negative regulation of astrocyte differentiation (GO:0048712)2.46121513
141Notch signaling involved in heart development (GO:0061314)2.45850410
142appendage development (GO:0048736)2.45516633
143limb development (GO:0060173)2.45516633
144generation of neurons (GO:0048699)2.45274716
145synapse organization (GO:0050808)2.44650286
146nonmotile primary cilium assembly (GO:0035058)2.44504116
147neuron projection extension involved in neuron projection guidance (GO:1902284)2.44400577
148axon extension involved in axon guidance (GO:0048846)2.44400577
149neuromuscular process controlling balance (GO:0050885)2.43591837
150outer ear morphogenesis (GO:0042473)2.43182606
151regulation of synaptic vesicle transport (GO:1902803)2.42900498
152cranial nerve development (GO:0021545)2.42138307
153tongue development (GO:0043586)2.39055890
154neuromuscular synaptic transmission (GO:0007274)2.38924863
155positive regulation of neuroblast proliferation (GO:0002052)2.37542718
156synaptic vesicle docking involved in exocytosis (GO:0016081)2.37494556

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.19863903
2GBX2_23144817_ChIP-Seq_PC3_Human3.35583935
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.91113062
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.90909255
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75195943
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.60752144
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.60752144
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.59209531
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.57726633
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.49673411
11* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.43104925
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.41534916
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.41030644
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40541823
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.35443118
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.35235138
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.30470387
18* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26350554
19AR_21572438_ChIP-Seq_LNCaP_Human2.26119407
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.20041765
21RBPJ_22232070_ChIP-Seq_NCS_Mouse2.18806009
22* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.14430471
23* DROSHA_22980978_ChIP-Seq_HELA_Human2.01856376
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.95183423
25* REST_21632747_ChIP-Seq_MESCs_Mouse1.89662375
26RARB_27405468_Chip-Seq_BRAIN_Mouse1.77123304
27TAF15_26573619_Chip-Seq_HEK293_Human1.74660545
28RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.74318804
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.72272101
30CBX2_27304074_Chip-Seq_ESCs_Mouse1.72021932
31OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.71993550
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.71462517
33RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.70140776
34POU5F1_16153702_ChIP-ChIP_HESCs_Human1.63745984
35REST_18959480_ChIP-ChIP_MESCs_Mouse1.61677062
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.61435753
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.60854393
38TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58511748
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56146930
40NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.46319100
41* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44878733
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.43174526
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.42707778
44POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.41270852
45TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41270852
46* SMAD3_21741376_ChIP-Seq_EPCs_Human1.40870155
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38701977
48SALL1_21062744_ChIP-ChIP_HESCs_Human1.32443561
49MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.32351158
50PIAS1_25552417_ChIP-Seq_VCAP_Human1.31346485
51RING1B_27294783_Chip-Seq_ESCs_Mouse1.31083769
52NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.29919227
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.29621276
54ZFP281_18757296_ChIP-ChIP_E14_Mouse1.28132408
55CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.27812492
56KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.27579072
57ER_23166858_ChIP-Seq_MCF-7_Human1.26336349
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25238508
59TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.24570568
60P300_19829295_ChIP-Seq_ESCs_Human1.23392739
61POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.23160438
62* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.22397843
63* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21620324
64ERG_21242973_ChIP-ChIP_JURKAT_Human1.21340006
65* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.21009511
66WT1_25993318_ChIP-Seq_PODOCYTE_Human1.20543094
67TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.20361227
68IKZF1_21737484_ChIP-ChIP_HCT116_Human1.19712553
69* ISL1_27105846_Chip-Seq_CPCs_Mouse1.19532886
70SMAD4_21799915_ChIP-Seq_A2780_Human1.18694997
71SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.18152149
72* RING1B_27294783_Chip-Seq_NPCs_Mouse1.17676473
73P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16938509
74BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16928656
75VDR_22108803_ChIP-Seq_LS180_Human1.16332710
76* SOX9_26525672_Chip-Seq_HEART_Mouse1.16224697
77TBX3_20139965_ChIP-Seq_MESCs_Mouse1.15974918
78CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15776011
79STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15695894
80SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.15348360
81TBX3_20139965_ChIP-Seq_ESCs_Mouse1.14789774
82STAT3_23295773_ChIP-Seq_U87_Human1.14532298
83* SMAD3_21741376_ChIP-Seq_ESCs_Human1.13641667
84SOX2_16153702_ChIP-ChIP_HESCs_Human1.13306849
85RNF2_27304074_Chip-Seq_NSC_Mouse1.12724679
86CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11763250
87KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.09282184
88KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.09282184
89KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.09282184
90POU3F2_20337985_ChIP-ChIP_501MEL_Human1.09030832
91TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06942729
92ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.06411669
93ZFP281_27345836_Chip-Seq_ESCs_Mouse1.06409603
94TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06371750
95EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05103329
96SOX2_21211035_ChIP-Seq_LN229_Gbm1.04437762
97GATA1_26923725_Chip-Seq_HPCs_Mouse1.03601106
98NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03249906
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01709288
100OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.99713387
101FUS_26573619_Chip-Seq_HEK293_Human0.99610710
102AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99560094
103NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.98872771
104TCF4_23295773_ChIP-Seq_U87_Human0.98173994
105POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.97878819
106EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97854748
107NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97631785
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97182088
109ARNT_22903824_ChIP-Seq_MCF-7_Human0.96919998
110EP300_21415370_ChIP-Seq_HL-1_Mouse0.94505738
111PRDM14_20953172_ChIP-Seq_ESCs_Human0.94449893
112DNAJC2_21179169_ChIP-ChIP_NT2_Human0.93814846
113AR_25329375_ChIP-Seq_VCAP_Human0.93812509
114LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93691789
115AHR_22903824_ChIP-Seq_MCF-7_Human0.93395267
116* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91988340
117* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90397611
118* SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.89916563
119ZNF217_24962896_ChIP-Seq_MCF-7_Human0.89703255
120ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89119899
121WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.89107265
122TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87849396
123CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.87331491
124IGF1R_20145208_ChIP-Seq_DFB_Human0.86201206
125TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86022645
126ZNF274_21170338_ChIP-Seq_K562_Hela0.85857555
127AR_19668381_ChIP-Seq_PC3_Human0.85838484
128RUNX2_22187159_ChIP-Seq_PCA_Human0.85311464
129MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.84034749
130RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.84003124
131TRIM28_21343339_ChIP-Seq_HEK293_Human0.83950215
132NANOG_18555785_Chip-Seq_ESCs_Mouse0.83829249

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.62561213
2MP0000920_abnormal_myelination4.01588441
3MP0004859_abnormal_synaptic_plasticity3.87339104
4MP0004270_analgesia3.20608131
5MP0001486_abnormal_startle_reflex2.83167688
6MP0003635_abnormal_synaptic_transmissio2.82582136
7MP0005423_abnormal_somatic_nervous2.82401853
8MP0002064_seizures2.74930327
9MP0002272_abnormal_nervous_system2.70313906
10MP0003329_amyloid_beta_deposits2.64955619
11MP0004885_abnormal_endolymph2.60924218
12MP0001529_abnormal_vocalization2.57223538
13MP0003690_abnormal_glial_cell2.54163865
14MP0009745_abnormal_behavioral_response2.45224986
15MP0000778_abnormal_nervous_system2.44317746
16MP0006292_abnormal_olfactory_placode2.40717099
17MP0003950_abnormal_plasma_membrane2.38859780
18MP0009046_muscle_twitch2.25407441
19MP0003634_abnormal_glial_cell2.20465758
20MP0004742_abnormal_vestibular_system2.20014457
21MP0002063_abnormal_learning/memory/cond2.19778435
22MP0004142_abnormal_muscle_tone2.11418694
23MP0002734_abnormal_mechanical_nocicepti2.07571020
24MP0001905_abnormal_dopamine_level2.05118261
25MP0010030_abnormal_orbit_morphology2.01826609
26MP0002572_abnormal_emotion/affect_behav2.01143468
27MP0005171_absent_coat_pigmentation2.00938645
28MP0005499_abnormal_olfactory_system1.96894207
29MP0005394_taste/olfaction_phenotype1.96894207
30MP0003122_maternal_imprinting1.90424758
31MP0008789_abnormal_olfactory_epithelium1.89755305
32MP0003136_yellow_coat_color1.83223830
33MP0000955_abnormal_spinal_cord1.78679712
34MP0005551_abnormal_eye_electrophysiolog1.77265931
35MP0008569_lethality_at_weaning1.76269490
36MP0001968_abnormal_touch/_nociception1.71562159
37MP0001293_anophthalmia1.67318305
38MP0001485_abnormal_pinna_reflex1.66869054
39MP0000049_abnormal_middle_ear1.66671282
40MP0002067_abnormal_sensory_capabilities1.65720121
41MP0001440_abnormal_grooming_behavior1.63216715
42MP0002249_abnormal_larynx_morphology1.63133155
43MP0002882_abnormal_neuron_morphology1.63107428
44MP0002229_neurodegeneration1.62662328
45MP0003632_abnormal_nervous_system1.59708133
46MP0002233_abnormal_nose_morphology1.58289336
47MP0001970_abnormal_pain_threshold1.53269880
48MP0003121_genomic_imprinting1.47428383
49MP0005409_darkened_coat_color1.45790987
50MP0003631_nervous_system_phenotype1.44900397
51MP0002736_abnormal_nociception_after1.44009327
52MP0002066_abnormal_motor_capabilities/c1.42503585
53MP0003633_abnormal_nervous_system1.41434473
54MP0005386_behavior/neurological_phenoty1.36716109
55MP0004924_abnormal_behavior1.36716109
56MP0001502_abnormal_circadian_rhythm1.35268748
57MP0002697_abnormal_eye_size1.35035515
58MP0002184_abnormal_innervation1.34826492
59MP0002733_abnormal_thermal_nociception1.34118714
60MP0000579_abnormal_nail_morphology1.33817550
61MP0005410_abnormal_fertilization1.32385075
62MP0002822_catalepsy1.31493268
63MP0003787_abnormal_imprinting1.27427023
64MP0000428_abnormal_craniofacial_morphol1.27307522
65MP0002557_abnormal_social/conspecific_i1.27129867
66MP0005248_abnormal_Harderian_gland1.26129472
67MP0002752_abnormal_somatic_nervous1.24749020
68MP0003283_abnormal_digestive_organ1.24267634
69MP0005646_abnormal_pituitary_gland1.23761331
70MP0002735_abnormal_chemical_nociception1.22858074
71MP0002638_abnormal_pupillary_reflex1.22520797
72MP0004043_abnormal_pH_regulation1.21966036
73MP0002938_white_spotting1.21798839
74MP0003119_abnormal_digestive_system1.20857876
75MP0001501_abnormal_sleep_pattern1.19899016
76MP0010368_abnormal_lymphatic_system1.19253949
77MP0000566_synostosis1.18769865
78MP0001963_abnormal_hearing_physiology1.18235171
79MP0002152_abnormal_brain_morphology1.17248598
80MP0004858_abnormal_nervous_system1.16886793
81MP0000604_amyloidosis1.16665658
82MP0005645_abnormal_hypothalamus_physiol1.16231656
83MP0009053_abnormal_anal_canal1.15878008
84MP0004811_abnormal_neuron_physiology1.13061164
85MP0001299_abnormal_eye_distance/1.11497061
86MP0003755_abnormal_palate_morphology1.10392579
87MP0005623_abnormal_meninges_morphology1.10231477
88MP0000462_abnormal_digestive_system1.09900418
89MP0004145_abnormal_muscle_electrophysio1.09734300
90MP0006072_abnormal_retinal_apoptosis1.07897693
91MP0009379_abnormal_foot_pigmentation1.07784719
92MP0000534_abnormal_ureter_morphology1.07146342
93MP0001177_atelectasis1.06967224
94MP0010678_abnormal_skin_adnexa1.05513933
95MP0001984_abnormal_olfaction1.05244725
96MP0000631_abnormal_neuroendocrine_gland1.03746303
97MP0002092_abnormal_eye_morphology1.03617523
98MP0009780_abnormal_chondrocyte_physiolo1.03175883
99MP0003385_abnormal_body_wall1.02492483
100MP0002090_abnormal_vision1.01779633
101MP0005195_abnormal_posterior_eye1.01329208
102MP0004134_abnormal_chest_morphology1.00623721
103MP0005377_hearing/vestibular/ear_phenot0.98898762
104MP0003878_abnormal_ear_physiology0.98898762
105MP0001879_abnormal_lymphatic_vessel0.98020428
106MP0002116_abnormal_craniofacial_bone0.97497537
107MP0003890_abnormal_embryonic-extraembry0.95941786
108MP0003942_abnormal_urinary_system0.95840493
109MP0004381_abnormal_hair_follicle0.95448178
110MP0001346_abnormal_lacrimal_gland0.95441048
111MP0002234_abnormal_pharynx_morphology0.93122225
112MP0005391_vision/eye_phenotype0.93085300
113MP0001286_abnormal_eye_development0.92014519
114MP0003935_abnormal_craniofacial_develop0.91902279
115MP0000747_muscle_weakness0.91251757
116MP0005253_abnormal_eye_physiology0.91097695
117MP0000026_abnormal_inner_ear0.90620917
118MP0008877_abnormal_DNA_methylation0.87711557
119MP0003137_abnormal_impulse_conducting0.87069827
120MP0002081_perinatal_lethality0.86602713
121MP0005187_abnormal_penis_morphology0.85919568
122MP0000383_abnormal_hair_follicle0.84064517
123MP0006276_abnormal_autonomic_nervous0.81646187
124MP0003938_abnormal_ear_development0.77855106
125MP0003861_abnormal_nervous_system0.76225163
126MP0004133_heterotaxia0.73938454
127MP0000647_abnormal_sebaceous_gland0.72952754
128MP0002069_abnormal_eating/drinking_beha0.69571289
129MP0001943_abnormal_respiration0.68968772
130MP0002653_abnormal_ependyma_morphology0.63160680
131MP0000467_abnormal_esophagus_morphology0.62651745
132MP0008260_abnormal_autophagy0.62183748
133MP0003075_altered_response_to0.57218078
134MP0003937_abnormal_limbs/digits/tail_de0.54331014
135MP0000762_abnormal_tongue_morphology0.54236743
136MP0004036_abnormal_muscle_relaxation0.52558888
137MP0004085_abnormal_heartbeat0.52465154
138MP0010769_abnormal_survival0.51809811
139MP0000537_abnormal_urethra_morphology0.50619040
140MP0010770_preweaning_lethality0.50250298

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)6.10513124
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.47039880
3Degeneration of the lateral corticospinal tracts (HP:0002314)5.47039880
4Myokymia (HP:0002411)4.71282067
5Cerebral inclusion bodies (HP:0100314)4.58565661
6Abnormality of the corticospinal tract (HP:0002492)4.49688271
7Peripheral hypomyelination (HP:0007182)4.36490137
8Supranuclear gaze palsy (HP:0000605)4.22194278
9Ankle clonus (HP:0011448)3.70935476
10Spastic gait (HP:0002064)3.61524680
11Megalencephaly (HP:0001355)3.57841939
12Alacrima (HP:0000522)3.53993537
13Dysmetria (HP:0001310)3.49267375
14Intention tremor (HP:0002080)3.48059954
15Cerebral hypomyelination (HP:0006808)3.45069185
16Onion bulb formation (HP:0003383)3.40032795
17Focal motor seizures (HP:0011153)3.31813931
18Sensory axonal neuropathy (HP:0003390)3.24751864
19Scanning speech (HP:0002168)3.23143182
20Termporal pattern (HP:0011008)3.18954454
21Insidious onset (HP:0003587)3.18954454
22Abnormal auditory evoked potentials (HP:0006958)3.16312185
23Parakeratosis (HP:0001036)2.97401302
24Hepatoblastoma (HP:0002884)2.95786698
25Action tremor (HP:0002345)2.95763775
26Absent septum pellucidum (HP:0001331)2.91467868
27Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.84780244
28Cutaneous finger syndactyly (HP:0010554)2.84236051
29Retinal dysplasia (HP:0007973)2.81183723
30Septo-optic dysplasia (HP:0100842)2.79464173
31Cortical dysplasia (HP:0002539)2.78589088
32Decreased lacrimation (HP:0000633)2.78421047
33Aplasia involving bones of the extremities (HP:0009825)2.75952623
34Aplasia involving bones of the upper limbs (HP:0009823)2.75952623
35Aplasia of the phalanges of the hand (HP:0009802)2.75952623
36Cutaneous syndactyly (HP:0012725)2.70523588
37Abnormality of the diencephalon (HP:0010662)2.69647228
38Epileptic encephalopathy (HP:0200134)2.68192383
39Clumsiness (HP:0002312)2.66045865
40Abnormality of the 4th metacarpal (HP:0010012)2.64262085
41Short 4th metacarpal (HP:0010044)2.63974126
42Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.63974126
43Anteriorly placed anus (HP:0001545)2.61325610
44Abnormality of the labia minora (HP:0012880)2.60712095
45Pheochromocytoma (HP:0002666)2.51009377
46Lower limb muscle weakness (HP:0007340)2.49687792
47Focal seizures (HP:0007359)2.49207534
48Thickened helices (HP:0000391)2.49007494
49High anterior hairline (HP:0009890)2.48533597
50Split foot (HP:0001839)2.47798144
51Progressive cerebellar ataxia (HP:0002073)2.47555284
52Dysdiadochokinesis (HP:0002075)2.46897216
53Abnormality of the septum pellucidum (HP:0007375)2.39883157
54Turricephaly (HP:0000262)2.39280016
55Increased circulating renin level (HP:0000848)2.37870870
56Urinary urgency (HP:0000012)2.35187281
57Morphological abnormality of the inner ear (HP:0011390)2.34073319
58Slow saccadic eye movements (HP:0000514)2.33565821
59Trigonocephaly (HP:0000243)2.30258454
60Rib fusion (HP:0000902)2.29898300
61Optic nerve hypoplasia (HP:0000609)2.27457645
62Bronchomalacia (HP:0002780)2.25963489
63Limb dystonia (HP:0002451)2.24917340
64Akinesia (HP:0002304)2.24628894
65Leukodystrophy (HP:0002415)2.24137808
66Premature skin wrinkling (HP:0100678)2.23061271
67Oligodactyly (HP:0012165)2.22254577
68Hemiparesis (HP:0001269)2.21806140
69Abnormality of the lower motor neuron (HP:0002366)2.20643727
70CNS hypomyelination (HP:0003429)2.20570035
71Broad-based gait (HP:0002136)2.20384317
72Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.20300027
73Clonus (HP:0002169)2.17951284
74Spastic tetraparesis (HP:0001285)2.16764431
75Preaxial foot polydactyly (HP:0001841)2.14780286
76Hypoplastic pelvis (HP:0008839)2.14121264
77Partial duplication of thumb phalanx (HP:0009944)2.13062989
78Hemiplegia (HP:0002301)2.12438404
79Segmental peripheral demyelination/remyelination (HP:0003481)2.12435753
80Aplasia/Hypoplasia of the sternum (HP:0006714)2.11805528
81Coronal craniosynostosis (HP:0004440)2.06804261
82Abnormality of the aortic arch (HP:0012303)2.06414996
83Neuroendocrine neoplasm (HP:0100634)2.06202646
84Morphological abnormality of the pyramidal tract (HP:0002062)2.05185598
85Aqueductal stenosis (HP:0002410)2.04743820
86Drooling (HP:0002307)2.03597203
87Humeroradial synostosis (HP:0003041)2.01416878
88Synostosis involving the elbow (HP:0003938)2.01416878
89Bowel incontinence (HP:0002607)2.00739771
90Renal hypoplasia (HP:0000089)2.00665856
91Metabolic alkalosis (HP:0200114)2.00147422
92Oligodactyly (hands) (HP:0001180)1.99196874
93Poor speech (HP:0002465)1.97388732
94Tracheomalacia (HP:0002779)1.97365613
95Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.97198262
96Neonatal short-limb short stature (HP:0008921)1.96847328
97Truncal ataxia (HP:0002078)1.93015417
98Visual hallucinations (HP:0002367)1.92990000
99Neuronal loss in central nervous system (HP:0002529)1.92507871
100Atonic seizures (HP:0010819)1.92234541
101Gastrointestinal atresia (HP:0002589)1.91499710
102Shallow orbits (HP:0000586)1.91380263
103Urinary bladder sphincter dysfunction (HP:0002839)1.91121287
104Postural instability (HP:0002172)1.90969222
105Overriding aorta (HP:0002623)1.89978854
106Anxiety (HP:0000739)1.89331291
107Vitreoretinal degeneration (HP:0000655)1.88543571
108Abnormality of binocular vision (HP:0011514)1.87466466
109Diplopia (HP:0000651)1.87466466
110Choanal stenosis (HP:0000452)1.85934154
111Colon cancer (HP:0003003)1.84967109
112Hammertoe (HP:0001765)1.83223834
113Hemivertebrae (HP:0002937)1.82130949
114Abnormal large intestine physiology (HP:0012700)1.81938438
115Foot dorsiflexor weakness (HP:0009027)1.80454461
116Elfin facies (HP:0004428)1.80306527
117Depression (HP:0000716)1.79804456
118Synostosis of carpal bones (HP:0005048)1.79463578
119Mutism (HP:0002300)1.79457008
120Dialeptic seizures (HP:0011146)1.79143757
121Generalized myoclonic seizures (HP:0002123)1.78618748
122Abnormal eating behavior (HP:0100738)1.78446908
123Choreoathetosis (HP:0001266)1.78408811
124Cerebral hemorrhage (HP:0001342)1.78193621
125Excessive salivation (HP:0003781)1.78045703
126Vaginal atresia (HP:0000148)1.78026869
127Gaze-evoked nystagmus (HP:0000640)1.77663985
128Urinary incontinence (HP:0000020)1.77457474
129Mixed hearing impairment (HP:0000410)1.77275855
130Partial agenesis of the corpus callosum (HP:0001338)1.76603574
131Decreased motor nerve conduction velocity (HP:0003431)1.76520036
132Hypoplasia of the iris (HP:0007676)1.75918033
133Fibular hypoplasia (HP:0003038)1.74387435
134Esophageal atresia (HP:0002032)1.73799363
135Spastic paraparesis (HP:0002313)1.73419881
136Hyperventilation (HP:0002883)1.72674426
137Broad thumb (HP:0011304)1.72221842
138Vertebral arch anomaly (HP:0008438)1.71143107
139Abnormality of the ischium (HP:0003174)1.69616968
140Abnormality of cochlea (HP:0000375)1.69257259
141Febrile seizures (HP:0002373)1.69115452
142Genital tract atresia (HP:0001827)1.69049469
143Polyphagia (HP:0002591)1.68938859
144Abnormality of the middle phalanges of the toes (HP:0010183)1.68559168
145Anophthalmia (HP:0000528)1.68258345
146Distal sensory impairment (HP:0002936)1.67866878
147Progressive inability to walk (HP:0002505)1.67763063
148Generalized tonic-clonic seizures (HP:0002069)1.66658758
149Intestinal atresia (HP:0011100)1.65736654
150Sleep apnea (HP:0010535)1.64496298
151Partial duplication of the phalanx of hand (HP:0009999)1.64138651
152Vertebral clefting (HP:0008428)1.64112785
153Renovascular hypertension (HP:0100817)1.63078291
154Calcaneovalgus deformity (HP:0001848)1.62903758
155Abnormality of the antihelix (HP:0009738)1.62710896
156Maternal diabetes (HP:0009800)1.62512216
157Increased nuchal translucency (HP:0010880)1.60982803
158Facial hemangioma (HP:0000329)1.60689580
159Difficulty running (HP:0009046)1.60035082
160Supernumerary spleens (HP:0009799)1.59715522
161Omphalocele (HP:0001539)1.58269191
162Thin ribs (HP:0000883)1.57241106
163Fetal akinesia sequence (HP:0001989)1.57224296
164Lissencephaly (HP:0001339)1.55278889
165Pachygyria (HP:0001302)1.52796192
166Renal dysplasia (HP:0000110)1.50941940
167Specific learning disability (HP:0001328)1.50333123
168Megalocornea (HP:0000485)1.49872807
169Impaired vibration sensation in the lower limbs (HP:0002166)1.49833946
170Midline defect of the nose (HP:0004122)1.49405571
171Anterior segment dysgenesis (HP:0007700)1.48426983
172Insomnia (HP:0100785)1.46525852
173Myotonia (HP:0002486)1.45409592
174Exercise-induced muscle cramps (HP:0003710)1.44998230

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.68193051
2OXSR13.52147168
3PKN12.45106935
4EPHA42.40679552
5MARK12.36762965
6EPHB12.35773618
7MAPKAPK52.26872906
8EPHB22.21182690
9PRPF4B2.16327634
10BCR2.12946770
11CDK192.08925050
12TNIK2.08327230
13FGFR22.04682666
14CASK2.02592594
15UHMK11.96690460
16PAK61.92900824
17TIE11.89448680
18WNK31.87517555
19NTRK21.85316151
20TYRO31.83657493
21NTRK11.75928399
22NTRK31.69851691
23NEK61.67618907
24WNK41.66546996
25LIMK11.61728432
26PNCK1.60273832
27CAMK2B1.59138182
28PHKG21.58902683
29PHKG11.58902683
30SGK2231.57223158
31SGK4941.57223158
32ROCK21.56204932
33PBK1.53521755
34WNK11.53064122
35MET1.45229032
36ICK1.42814780
37MKNK21.42682263
38FGR1.42052323
39CSNK1G31.36701345
40PRKD31.35555938
41MAP3K101.31392053
42MAP3K91.29450772
43CDK51.28382473
44CSNK1A1L1.28072220
45CAMK2D1.27373226
46MKNK11.22995050
47CSNK1G21.21446662
48KSR21.08828872
49CLK11.08663144
50CDK141.06069017
51MAPK131.04258827
52CAMK2A1.03696284
53CDK151.03518888
54CAMK2G1.03504033
55DYRK21.03222652
56MINK11.00915828
57PAK31.00414871
58MOS1.00310860
59CDK181.00291493
60MAP3K40.99789607
61PDGFRA0.99081003
62CSNK1G10.98337699
63MARK20.95030663
64EEF2K0.94561171
65CDK11A0.93266848
66TSSK60.91299000
67LATS20.90443147
68CDC70.90091616
69MAP3K130.86808921
70KSR10.86492256
71SGK20.86200025
72FES0.83414764
73PRKCE0.76711010
74MUSK0.74200598
75STK38L0.72987527
76DYRK1A0.72912510
77INSRR0.72648778
78SRPK10.72305545
79IRAK20.72185676
80PRKD10.72051651
81WEE10.71418134
82TESK20.69927790
83SIK20.69323973
84PRKCH0.68108700
85DAPK20.67144536
86FYN0.63992521
87DMPK0.61599627
88STK240.58435554
89BRSK10.57667411
90STK110.56891503
91BRD40.56833340
92PDPK10.55724754
93LMTK20.55641374
94PRKCQ0.55514811
95MAP2K70.53124340
96TTK0.51903705
97CAMK1G0.51556965
98SGK30.51172898
99MAPK150.50993470
100PRKCG0.50905045
101MAP2K40.50819279
102PLK20.50185150
103BMPR1B0.49905525
104PLK30.49077907
105CAMK1D0.48599154
106PRKG10.48347505
107FGFR10.46734611
108DDR20.46304549
109RIPK10.45707803
110CSNK1D0.45516823
111PINK10.45454526
112CDK30.45376220
113ERBB40.44539511
114PRKACB0.44212697
115CAMK10.43388839
116OBSCN0.43106490
117ARAF0.43098578
118CAMKK10.42882109
119CAMK40.41949166
120EPHA30.41761203
121CSNK1A10.41562633
122PRKDC0.40450354
123PRKCZ0.40187019
124PDGFRB0.39995205
125MAPK100.39653806
126SGK10.39507359
127NME10.39120657
128BMX0.38644294
129GRK50.38369502
130YES10.37663587
131RPS6KA30.33629492
132ERBB20.33629216
133ROCK10.33307729
134PTK2B0.33195340
135SRC0.32319985
136PRKACA0.32292470
137GSK3A0.32212802
138MAP3K20.31681200

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.63243781
2Steroid biosynthesis_Homo sapiens_hsa001003.14561015
3Fatty acid elongation_Homo sapiens_hsa000622.85922813
4GABAergic synapse_Homo sapiens_hsa047272.45403011
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.39403511
6Nicotine addiction_Homo sapiens_hsa050332.38755792
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.37189117
8Nitrogen metabolism_Homo sapiens_hsa009102.25621726
9Glutamatergic synapse_Homo sapiens_hsa047242.20765098
10Ether lipid metabolism_Homo sapiens_hsa005652.16143611
11Morphine addiction_Homo sapiens_hsa050322.06699974
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.03440223
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.99481051
14Axon guidance_Homo sapiens_hsa043601.96463314
15Circadian entrainment_Homo sapiens_hsa047131.89413217
16Synaptic vesicle cycle_Homo sapiens_hsa047211.88588009
17Hippo signaling pathway_Homo sapiens_hsa043901.79918957
18Serotonergic synapse_Homo sapiens_hsa047261.67281968
19Vitamin B6 metabolism_Homo sapiens_hsa007501.59300409
20Salivary secretion_Homo sapiens_hsa049701.51595991
21Cocaine addiction_Homo sapiens_hsa050301.51161863
22Long-term depression_Homo sapiens_hsa047301.51091657
23Notch signaling pathway_Homo sapiens_hsa043301.45158742
24Dopaminergic synapse_Homo sapiens_hsa047281.41942748
25Olfactory transduction_Homo sapiens_hsa047401.40453055
26Cholinergic synapse_Homo sapiens_hsa047251.38557495
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.38129034
28Gastric acid secretion_Homo sapiens_hsa049711.37352627
29Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.34207360
30Amphetamine addiction_Homo sapiens_hsa050311.26335183
31Sphingolipid metabolism_Homo sapiens_hsa006001.25608242
32Adherens junction_Homo sapiens_hsa045201.23279683
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.20150746
34Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.19362421
35Insulin secretion_Homo sapiens_hsa049111.18378419
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.16736882
37Long-term potentiation_Homo sapiens_hsa047201.14970848
38Gap junction_Homo sapiens_hsa045401.10231130
39Renal cell carcinoma_Homo sapiens_hsa052111.10000098
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09559900
41Renin secretion_Homo sapiens_hsa049241.09447785
42Collecting duct acid secretion_Homo sapiens_hsa049661.05802282
43Taste transduction_Homo sapiens_hsa047421.04560698
44Dorso-ventral axis formation_Homo sapiens_hsa043201.04536632
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04486587
46Oocyte meiosis_Homo sapiens_hsa041141.03189965
47Cardiac muscle contraction_Homo sapiens_hsa042601.03169170
48Sulfur metabolism_Homo sapiens_hsa009201.00018476
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99053446
50Butanoate metabolism_Homo sapiens_hsa006500.99049871
51Oxidative phosphorylation_Homo sapiens_hsa001900.98516514
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.97935209
53Lysine degradation_Homo sapiens_hsa003100.96329598
54Sphingolipid signaling pathway_Homo sapiens_hsa040710.95657303
55Vibrio cholerae infection_Homo sapiens_hsa051100.92649127
56Glioma_Homo sapiens_hsa052140.91998104
57Calcium signaling pathway_Homo sapiens_hsa040200.91841492
58Phototransduction_Homo sapiens_hsa047440.90326224
59Oxytocin signaling pathway_Homo sapiens_hsa049210.90235601
60Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88276661
61Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88261590
62cAMP signaling pathway_Homo sapiens_hsa040240.86870252
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86629241
64Colorectal cancer_Homo sapiens_hsa052100.86496065
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.85554462
66Bile secretion_Homo sapiens_hsa049760.84984664
67Tight junction_Homo sapiens_hsa045300.83300434
68ErbB signaling pathway_Homo sapiens_hsa040120.81919879
69Endometrial cancer_Homo sapiens_hsa052130.81825046
70mRNA surveillance pathway_Homo sapiens_hsa030150.81208605
71Alzheimers disease_Homo sapiens_hsa050100.80149272
72Propanoate metabolism_Homo sapiens_hsa006400.78530715
73Fatty acid biosynthesis_Homo sapiens_hsa000610.78515179
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.78503665
75MicroRNAs in cancer_Homo sapiens_hsa052060.77519089
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76785574
77Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.76065879
78Pancreatic secretion_Homo sapiens_hsa049720.75133780
79Linoleic acid metabolism_Homo sapiens_hsa005910.74652690
80Endocytosis_Homo sapiens_hsa041440.73777510
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73580411
82Ras signaling pathway_Homo sapiens_hsa040140.72272422
83Parkinsons disease_Homo sapiens_hsa050120.71586635
84Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71278215
85Melanogenesis_Homo sapiens_hsa049160.70987607
86Arginine and proline metabolism_Homo sapiens_hsa003300.70752490
87Hedgehog signaling pathway_Homo sapiens_hsa043400.70493735
88GnRH signaling pathway_Homo sapiens_hsa049120.70298332
89Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.65983613
90Choline metabolism in cancer_Homo sapiens_hsa052310.65724716
91Cell cycle_Homo sapiens_hsa041100.65401199
92Protein digestion and absorption_Homo sapiens_hsa049740.65323934
93Circadian rhythm_Homo sapiens_hsa047100.64552462
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.63614444
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63297374
96Histidine metabolism_Homo sapiens_hsa003400.63172012
97Prion diseases_Homo sapiens_hsa050200.60939942
98Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60379510
992-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59635089
100Ovarian steroidogenesis_Homo sapiens_hsa049130.58271789
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.56895728
102TGF-beta signaling pathway_Homo sapiens_hsa043500.56842563
103Biosynthesis of amino acids_Homo sapiens_hsa012300.56796741
104Mineral absorption_Homo sapiens_hsa049780.56390657
105Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56190987
106Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55284574
107Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54203891
108cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53709287
109AMPK signaling pathway_Homo sapiens_hsa041520.53651252
110Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51939658
111Estrogen signaling pathway_Homo sapiens_hsa049150.51048497
112Dilated cardiomyopathy_Homo sapiens_hsa054140.49927737
113Fatty acid metabolism_Homo sapiens_hsa012120.48197434
114ECM-receptor interaction_Homo sapiens_hsa045120.47146730
115Alcoholism_Homo sapiens_hsa050340.46806832
116Wnt signaling pathway_Homo sapiens_hsa043100.46033619
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.45855694
118MAPK signaling pathway_Homo sapiens_hsa040100.45813807
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.45357797
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.43086266
121Pathways in cancer_Homo sapiens_hsa052000.43080877
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42740839
123Melanoma_Homo sapiens_hsa052180.41533375
124Thyroid hormone synthesis_Homo sapiens_hsa049180.40941217
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40567135
126Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39776387
127Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39373038
128Lysosome_Homo sapiens_hsa041420.38668348
129Rap1 signaling pathway_Homo sapiens_hsa040150.37256523
130Basal cell carcinoma_Homo sapiens_hsa052170.36518722

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