WWTR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vascular endothelial growth factor signaling pathway (GO:0038084)4.69842175
2lymph vessel development (GO:0001945)4.56695560
3basement membrane organization (GO:0071711)4.42609636
4protein heterotrimerization (GO:0070208)4.41966103
5retina vasculature morphogenesis in camera-type eye (GO:0061299)4.39539152
6collagen fibril organization (GO:0030199)4.38400819
7chondrocyte proliferation (GO:0035988)4.13194148
8endothelial cell morphogenesis (GO:0001886)3.98052621
9glomerular basement membrane development (GO:0032836)3.83366506
10lymphangiogenesis (GO:0001946)3.79562863
11substrate-dependent cell migration (GO:0006929)3.78911688
12hemidesmosome assembly (GO:0031581)3.75914232
13cell migration involved in sprouting angiogenesis (GO:0002042)3.74979273
14regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.73578098
15* hippo signaling (GO:0035329)3.65637734
16endodermal cell differentiation (GO:0035987)3.61680875
17cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.60621613
18renal filtration (GO:0097205)3.59765115
19plasma membrane repair (GO:0001778)3.52790889
20cell adhesion mediated by integrin (GO:0033627)3.52131461
21glomerular filtration (GO:0003094)3.43114046
22neuron projection extension involved in neuron projection guidance (GO:1902284)3.36143833
23axon extension involved in axon guidance (GO:0048846)3.36143833
24epithelial cell-cell adhesion (GO:0090136)3.35198506
25blood vessel maturation (GO:0001955)3.31837556
26muscle cell migration (GO:0014812)3.28947442
27paraxial mesoderm development (GO:0048339)3.26138707
28wound healing, spreading of epidermal cells (GO:0035313)3.24714503
29regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.21739542
30bone trabecula formation (GO:0060346)3.21032433
31collagen metabolic process (GO:0032963)3.18405297
32skin morphogenesis (GO:0043589)3.14710305
33vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.10821738
34notochord development (GO:0030903)3.10527929
35regulation of integrin-mediated signaling pathway (GO:2001044)3.08385345
36negative regulation of chondrocyte differentiation (GO:0032331)3.08247475
37collagen catabolic process (GO:0030574)3.07429931
38blood vessel endothelial cell migration (GO:0043534)3.05441527
39multicellular organismal macromolecule metabolic process (GO:0044259)3.03678983
40cell-substrate junction assembly (GO:0007044)3.03444885
41regulation of cardioblast differentiation (GO:0051890)3.02622379
42regulation of endothelial cell differentiation (GO:0045601)3.01888381
43extracellular fibril organization (GO:0043206)2.99499237
44regulation of tight junction assembly (GO:2000810)2.97858421
45COPI coating of Golgi vesicle (GO:0048205)2.96821071
46Golgi transport vesicle coating (GO:0048200)2.96821071
47atrioventricular valve morphogenesis (GO:0003181)2.94584946
48extracellular matrix disassembly (GO:0022617)2.93598276
49endothelium development (GO:0003158)2.92699688
50branching involved in salivary gland morphogenesis (GO:0060445)2.91640230
51ganglion development (GO:0061548)2.90500863
52multicellular organismal metabolic process (GO:0044236)2.89392050
53sprouting angiogenesis (GO:0002040)2.89128376
54negative regulation of protein localization to cell surface (GO:2000009)2.88106520
55trabecula formation (GO:0060343)2.87225208
56dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.87138118
57protein localization to cell surface (GO:0034394)2.85656546
58endothelial cell chemotaxis (GO:0035767)2.85282968
59positive regulation of endothelial cell apoptotic process (GO:2000353)2.85232833
60multicellular organismal catabolic process (GO:0044243)2.85061139
61positive regulation of astrocyte differentiation (GO:0048711)2.84827028
62positive regulation of osteoblast proliferation (GO:0033690)2.84646880
63heart trabecula formation (GO:0060347)2.84260272
64surfactant homeostasis (GO:0043129)2.81758683
65regulation of hippo signaling (GO:0035330)2.80171489
66chondrocyte development (GO:0002063)2.79568793
67endocardial cushion development (GO:0003197)2.79251870
68cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.78862775
69regulation of glomerular filtration (GO:0003093)2.77252096
70adherens junction assembly (GO:0034333)2.77012290
71fibroblast migration (GO:0010761)2.76181127
72substrate adhesion-dependent cell spreading (GO:0034446)2.74733270
73negative regulation of cartilage development (GO:0061037)2.74676130
74negative regulation of fatty acid transport (GO:2000192)2.74614258
75regulation of transforming growth factor beta2 production (GO:0032909)2.74529707
76sequestering of extracellular ligand from receptor (GO:0035581)2.72414854
77regulation of chondrocyte differentiation (GO:0032330)2.71911388
78mesenchymal-epithelial cell signaling (GO:0060638)2.71872292
79positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.71248640
80polarized epithelial cell differentiation (GO:0030859)2.68750526
81Notch signaling involved in heart development (GO:0061314)2.68735608
82protein hydroxylation (GO:0018126)2.67917352
83mesodermal cell differentiation (GO:0048333)2.67314615
84kidney mesenchyme development (GO:0072074)2.66868365
85artery development (GO:0060840)2.66017556
86positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.64607302
87cell migration involved in heart development (GO:0060973)2.64523035
88lung vasculature development (GO:0060426)2.63713915
89negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.63653204
90mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.63409679
91peptidyl-proline hydroxylation (GO:0019511)2.63398281
92maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.62931764
93gap junction assembly (GO:0016264)2.62280278
94insulin-like growth factor receptor signaling pathway (GO:0048009)2.61350854
95response to gravity (GO:0009629)2.60897795
96blood vessel remodeling (GO:0001974)2.60791407
97apoptotic cell clearance (GO:0043277)2.60574485
98positive regulation of mesenchymal cell proliferation (GO:0002053)2.60527717
99dermatan sulfate biosynthetic process (GO:0030208)2.59638173
100semaphorin-plexin signaling pathway (GO:0071526)2.58526797
101cardiac myofibril assembly (GO:0055003)2.57427456
102regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.57164859
103G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.57054009
104glomerular visceral epithelial cell development (GO:0072015)2.56483034
105regulation of heart morphogenesis (GO:2000826)2.55917914
106negative regulation of smooth muscle cell migration (GO:0014912)2.55021673
107positive regulation of extracellular matrix organization (GO:1903055)2.54378343
108cell surface receptor signaling pathway involved in heart development (GO:0061311)2.53803915
109patterning of blood vessels (GO:0001569)2.53797833
110positive regulation of endothelial cell migration (GO:0010595)2.53760011
111* regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.53157188
112protein retention in ER lumen (GO:0006621)2.52291237
113type B pancreatic cell proliferation (GO:0044342)2.52161536
114lung-associated mesenchyme development (GO:0060484)2.51982601
115heart valve morphogenesis (GO:0003179)2.51587625
116organ formation (GO:0048645)2.51539552
117extracellular matrix organization (GO:0030198)2.51273228
118stress fiber assembly (GO:0043149)2.51270003
119wound healing, spreading of cells (GO:0044319)2.51007457
120vasculogenesis (GO:0001570)2.50988386
121tissue remodeling (GO:0048771)2.50931101
122extracellular structure organization (GO:0043062)2.50426430
123embryonic foregut morphogenesis (GO:0048617)2.50383827
124keratan sulfate catabolic process (GO:0042340)2.50258167
125regulation of p38MAPK cascade (GO:1900744)2.50155256
126ovulation from ovarian follicle (GO:0001542)2.48938266
127positive regulation of cartilage development (GO:0061036)2.47922534
128regulation of mesenchymal cell proliferation (GO:0010464)2.47783889
129metanephric mesenchyme development (GO:0072075)2.46924752
130regulation of cell fate specification (GO:0042659)2.46868923
131regulation of cartilage development (GO:0061035)2.46616855
132mammary gland development (GO:0030879)2.46109011
133cell-substrate adhesion (GO:0031589)2.45914280
134myoblast fusion (GO:0007520)2.45058699
135positive regulation of blood vessel endothelial cell migration (GO:0043536)2.44618288
136regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.44439626
137positive regulation of fatty acid oxidation (GO:0046321)2.43152264
138positive regulation of fatty acid beta-oxidation (GO:0032000)2.42773181
139cell-matrix adhesion (GO:0007160)2.42189255
140positive regulation of epithelial cell migration (GO:0010634)2.42062392
141ventricular cardiac muscle cell development (GO:0055015)2.41203812
142SMAD protein complex assembly (GO:0007183)2.39897136
143membrane raft organization (GO:0031579)2.39232457
144negative regulation of axon extension involved in axon guidance (GO:0048843)2.37993958
145regulation of axon extension involved in axon guidance (GO:0048841)2.37816091
146cellular response to vitamin D (GO:0071305)2.37748742
147negative regulation of nitric-oxide synthase activity (GO:0051001)2.37283840
148protein localization to endosome (GO:0036010)2.34955614

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.24803839
2TRIM28_21343339_ChIP-Seq_HEK293_Human5.85481845
3* RARG_19884340_ChIP-ChIP_MEFs_Mouse4.05595022
4CLOCK_20551151_ChIP-Seq_293T_Human3.52992820
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.35581496
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.28107088
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.72642728
8HIF1A_21447827_ChIP-Seq_MCF-7_Human2.43607411
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.43078445
10EP300_21415370_ChIP-Seq_HL-1_Mouse2.36829448
11ESR1_21235772_ChIP-Seq_MCF-7_Human2.33979158
12TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.29211148
13CJUN_26792858_Chip-Seq_BT549_Human2.28330014
14SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.16601811
15ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.14963109
16RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.10900334
17ESR2_21235772_ChIP-Seq_MCF-7_Human2.10689620
18* PPAR_26484153_Chip-Seq_NCI-H1993_Human2.08096530
19TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.04735741
20CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.03368477
21EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.99359187
22ZNF263_19887448_ChIP-Seq_K562_Human1.95498474
23* NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.93307890
24SALL4_18804426_ChIP-ChIP_XEN_Mouse1.92492844
25* WT1_19549856_ChIP-ChIP_CCG9911_Human1.87673861
26* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.86610200
27RBPJ_22232070_ChIP-Seq_NCS_Mouse1.83074401
28* BRD4_25478319_ChIP-Seq_HGPS_Human1.79489147
29* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.73102969
30* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.73102969
31FOXO3_23340844_ChIP-Seq_DLD1_Human1.69129867
32SOX9_24532713_ChIP-Seq_HFSC_Mouse1.64977707
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.64967660
34CDX2_19796622_ChIP-Seq_MESCs_Mouse1.63784652
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.62249163
36* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.61710177
37TBX20_22328084_ChIP-Seq_HEART_Mouse1.60165401
38TBX20_22080862_ChIP-Seq_HEART_Mouse1.60165401
39ZNF217_24962896_ChIP-Seq_MCF-7_Human1.59915989
40GATA2_21666600_ChIP-Seq_HMVEC_Human1.56380685
41SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.56369191
42STAT6_21828071_ChIP-Seq_BEAS2B_Human1.55618512
43ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.50963484
44KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.50625373
45ELK3_25401928_ChIP-Seq_HUVEC_Human1.50139251
46NRF2_20460467_ChIP-Seq_MEFs_Mouse1.48382787
47NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.48382787
48TCF3_18692474_ChIP-Seq_MEFs_Mouse1.45075862
49* UBF1/2_26484160_Chip-Seq_HMECs_Human1.42959509
50SALL1_21062744_ChIP-ChIP_HESCs_Human1.40778727
51KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.38358765
52KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.38358765
53KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.38358765
54P300_27058665_Chip-Seq_ZR-75-30cells_Human1.36169650
55EED_16625203_ChIP-ChIP_MESCs_Mouse1.34928672
56SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.34528420
57* SOX2_20726797_ChIP-Seq_SW620_Human1.34251634
58ESR1_20079471_ChIP-ChIP_T-47D_Human1.32076153
59ATF3_27146783_Chip-Seq_COLON_Human1.30810943
60STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.29665075
61AR_21909140_ChIP-Seq_LNCAP_Human1.27421275
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.26411153
63CTNNB1_20460455_ChIP-Seq_HCT116_Human1.26090971
64* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.25416659
65MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.24792489
66* ISL1_27105846_Chip-Seq_CPCs_Mouse1.23335514
67ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.22123993
68SMAD_19615063_ChIP-ChIP_OVARY_Human1.22088398
69HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.21453015
70* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21371421
71TP53_20018659_ChIP-ChIP_R1E_Mouse1.20166691
72TCF4_18268006_ChIP-ChIP_LS174T_Human1.19381206
73TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17841160
74PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.17586834
75TP53_16413492_ChIP-PET_HCT116_Human1.15711058
76SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.15556625
77CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.15391460
78RACK7_27058665_Chip-Seq_MCF-7_Human1.14610645
79SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.14578092
80TP53_18474530_ChIP-ChIP_U2OS_Human1.13890688
81SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13103463
82ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.12851664
83RNF2_18974828_ChIP-Seq_MESCs_Mouse1.10808762
84EZH2_18974828_ChIP-Seq_MESCs_Mouse1.10808762
85TP53_22127205_ChIP-Seq_IMR90_Human1.10738457
86* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10355553
87SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.10160595
88PIAS1_25552417_ChIP-Seq_VCAP_Human1.10059697
89SMC1_22415368_ChIP-Seq_MEFs_Mouse1.09682975
90PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.09447165
91TP53_23651856_ChIP-Seq_MEFs_Mouse1.08416612
92EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.08011036
93NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.07694721
94AHR_22903824_ChIP-Seq_MCF-7_Human1.05745382
95NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.05401746
96LXR_22158963_ChIP-Seq_LIVER_Mouse1.05202702
97SOX17_20123909_ChIP-Seq_XEN_Mouse1.04869192
98RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.02532017
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.01958927
100* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01877591
101P63_26484246_Chip-Seq_KERATINOCYTES_Human1.00750367
102SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99802954
103TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.99286661
104SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.98509412
105CDX2_20551321_ChIP-Seq_CACO-2_Human0.97129439
106* TP63_23658742_ChIP-Seq_EP156T_Human0.96274748
107RUNX1_27514584_Chip-Seq_MCF-7_Human0.96044775
108* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.95839907
109PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.95693452
110ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.95271678
111NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94809868
112ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.94517898
113SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92969963
114RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.92815038
115TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91823854
116* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91766676
117TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.91539770
118* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90574214
119FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.90139060
120* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.90131481
121KDM2B_26808549_Chip-Seq_SUP-B15_Human0.89845142
122GATA3_24758297_ChIP-Seq_MCF-7_Human0.89642711
123ARNT_22903824_ChIP-Seq_MCF-7_Human0.88722843
124TBX3_20139965_ChIP-Seq_ESCs_Mouse0.88597874
125* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.88166266
126RXR_22108803_ChIP-Seq_LS180_Human0.88005744
127TBX3_20139965_ChIP-Seq_MESCs_Mouse0.87972952
128FOXM1_26456572_ChIP-Seq_MCF-7_Human0.87519207
129SA1_22415368_ChIP-Seq_MEFs_Mouse0.87292034

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.56280737
2MP0004272_abnormal_basement_membrane4.10906372
3MP0005275_abnormal_skin_tensile4.03619382
4MP0005503_abnormal_tendon_morphology3.45047345
5MP0003705_abnormal_hypodermis_morpholog3.44171889
6MP0010368_abnormal_lymphatic_system2.78067707
7MP0005623_abnormal_meninges_morphology2.69529343
8MP0003279_aneurysm2.60158945
9MP0001879_abnormal_lymphatic_vessel2.45636219
10MP0009384_cardiac_valve_regurgitation2.13522475
11MP0003566_abnormal_cell_adhesion2.09553161
12MP0006054_spinal_hemorrhage1.95413543
13MP0003941_abnormal_skin_development1.90574790
14MP0004084_abnormal_cardiac_muscle1.89934451
15* MP0001958_emphysema1.81282974
16MP0000750_abnormal_muscle_regeneration1.70374506
17MP0000733_abnormal_muscle_development1.64129849
18MP0002060_abnormal_skin_morphology1.62052009
19MP0002108_abnormal_muscle_morphology1.61806303
20MP0000751_myopathy1.58741441
21MP0010030_abnormal_orbit_morphology1.58224413
22* MP0005508_abnormal_skeleton_morphology1.55628632
23MP0005023_abnormal_wound_healing1.50509300
24MP0010352_gastrointestinal_tract_polyps1.49733965
25MP0000767_abnormal_smooth_muscle1.49718699
26MP0003091_abnormal_cell_migration1.49423145
27MP0006138_congestive_heart_failure1.47738988
28MP0003828_pulmonary_edema1.47012163
29MP0009053_abnormal_anal_canal1.46495473
30MP0002295_abnormal_pulmonary_circulatio1.45992392
31MP0003950_abnormal_plasma_membrane1.45553199
32MP0000537_abnormal_urethra_morphology1.45410226
33MP0009250_abnormal_appendicular_skeleto1.44827149
34MP0002282_abnormal_trachea_morphology1.41325431
35MP0002896_abnormal_bone_mineralization1.37346559
36MP0004858_abnormal_nervous_system1.35362153
37MP0000013_abnormal_adipose_tissue1.31909358
38MP0003385_abnormal_body_wall1.31113837
39MP0005670_abnormal_white_adipose1.23277362
40MP0005197_abnormal_uvea_morphology1.20837396
41MP0001915_intracranial_hemorrhage1.20324766
42MP0005330_cardiomyopathy1.19162979
43MP0010630_abnormal_cardiac_muscle1.18411200
44MP0004087_abnormal_muscle_fiber1.18255034
45MP0000762_abnormal_tongue_morphology1.15776554
46MP0005167_abnormal_blood-brain_barrier1.11339935
47MP0005666_abnormal_adipose_tissue1.10573315
48MP0000163_abnormal_cartilage_morphology1.10251586
49MP0003115_abnormal_respiratory_system1.09687856
50MP0003045_fibrosis1.07961841
51MP0004185_abnormal_adipocyte_glucose1.07090657
52MP0000534_abnormal_ureter_morphology1.06965551
53MP0004215_abnormal_myocardial_fiber1.06561234
54MP0000003_abnormal_adipose_tissue1.05825807
55MP0002128_abnormal_blood_circulation1.05790775
56MP0010234_abnormal_vibrissa_follicle1.05430557
57MP0000428_abnormal_craniofacial_morphol1.03339437
58MP0002925_abnormal_cardiovascular_devel1.02878270
59MP0008775_abnormal_heart_ventricle1.02746523
60MP0001542_abnormal_bone_strength1.02277357
61MP0001299_abnormal_eye_distance/1.02009244
62MP0005375_adipose_tissue_phenotype1.01856226
63MP0003942_abnormal_urinary_system1.01147470
64MP0005165_increased_susceptibility_to1.01065858
65MP0005257_abnormal_intraocular_pressure1.00457585
66MP0005385_cardiovascular_system_phenoty1.00452914
67MP0001544_abnormal_cardiovascular_syste1.00452914
68MP0003935_abnormal_craniofacial_develop0.98654482
69MP0001614_abnormal_blood_vessel0.97969958
70MP0000749_muscle_degeneration0.96194982
71MP0002972_abnormal_cardiac_muscle0.95946254
72MP0005076_abnormal_cell_differentiation0.95909395
73MP0002168_other_aberrant_phenotype0.95568944
74MP0002115_abnormal_skeleton_extremities0.95434856
75MP0003755_abnormal_palate_morphology0.93927976
76MP0003567_abnormal_fetal_cardiomyocyte0.93927017
77MP0004484_altered_response_of0.93775987
78MP0001849_ear_inflammation0.92874083
79MP0003937_abnormal_limbs/digits/tail_de0.92816356
80MP0005620_abnormal_muscle_contractility0.92077728
81MP0005595_abnormal_vascular_smooth0.91296319
82MP0004036_abnormal_muscle_relaxation0.90947646
83MP0000516_abnormal_urinary_system0.90446620
84MP0005367_renal/urinary_system_phenotyp0.90446620
85MP0002796_impaired_skin_barrier0.90253982
86MP0005409_darkened_coat_color0.90135731
87MP0005248_abnormal_Harderian_gland0.89771271
88MP0000432_abnormal_head_morphology0.88483212
89MP0002877_abnormal_melanocyte_morpholog0.86799014
90MP0002249_abnormal_larynx_morphology0.86042365
91MP0002697_abnormal_eye_size0.85280923
92MP0002932_abnormal_joint_morphology0.85149540
93MP0005164_abnormal_response_to0.84218552
94MP0005408_hypopigmentation0.83019934
95MP0001661_extended_life_span0.82884316
96MP0001243_abnormal_dermal_layer0.82856111
97MP0003283_abnormal_digestive_organ0.81427502
98MP0004134_abnormal_chest_morphology0.81310372
99MP0005193_abnormal_anterior_eye0.81114670
100MP0004130_abnormal_muscle_cell0.80874926
101MP0002837_dystrophic_cardiac_calcinosis0.80864429
102MP0000266_abnormal_heart_morphology0.80616395
103MP0002233_abnormal_nose_morphology0.80426312
104MP0004233_abnormal_muscle_weight0.79042160
105MP0002269_muscular_atrophy0.78770080
106MP0000467_abnormal_esophagus_morphology0.78627257
107MP0009780_abnormal_chondrocyte_physiolo0.76714456
108MP0005369_muscle_phenotype0.76061005
109MP0005171_absent_coat_pigmentation0.76013468
110MP0000759_abnormal_skeletal_muscle0.75983907
111MP0002938_white_spotting0.75818109
112MP0009379_abnormal_foot_pigmentation0.75072416
113MP0010678_abnormal_skin_adnexa0.74620084
114* MP0002113_abnormal_skeleton_development0.74366956
115MP0000049_abnormal_middle_ear0.73178883
116MP0002092_abnormal_eye_morphology0.70714177
117MP0002933_joint_inflammation0.70623625
118MP0000613_abnormal_salivary_gland0.70063547
119MP0000647_abnormal_sebaceous_gland0.67070932
120MP0002127_abnormal_cardiovascular_syste0.67035742
121MP0002116_abnormal_craniofacial_bone0.66415010
122MP0000747_muscle_weakness0.66127304
123MP0009697_abnormal_copulation0.65492871

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.89772918
2Premature rupture of membranes (HP:0001788)5.75587414
3Ankle contracture (HP:0006466)4.23165681
4Broad metatarsal (HP:0001783)4.15366608
5Shallow orbits (HP:0000586)4.07572743
6Atrophic scars (HP:0001075)3.69368852
7Increased connective tissue (HP:0009025)3.67578870
8Aortic dissection (HP:0002647)3.60851198
9Cerebral aneurysm (HP:0004944)3.53856407
10Spinal rigidity (HP:0003306)3.23732514
11Cervical subluxation (HP:0003308)3.20820152
12Neonatal short-limb short stature (HP:0008921)3.13433411
13Aortic aneurysm (HP:0004942)3.11308028
14Soft skin (HP:0000977)3.10088413
15Type 1 muscle fiber predominance (HP:0003803)2.99690823
16Muscle fiber splitting (HP:0003555)2.96285523
17Hypoplastic ischia (HP:0003175)2.93759949
18Fragile skin (HP:0001030)2.81301106
19Follicular hyperkeratosis (HP:0007502)2.78769895
20Mitral valve prolapse (HP:0001634)2.78696389
21Abnormality of the ischium (HP:0003174)2.72314347
22Wrist flexion contracture (HP:0001239)2.69306073
23Dilatation of the ascending aorta (HP:0005111)2.65866748
24Right ventricular cardiomyopathy (HP:0011663)2.63591287
25Pterygium (HP:0001059)2.63289025
26Bladder diverticulum (HP:0000015)2.60145248
27Popliteal pterygium (HP:0009756)2.60008974
28Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.49161607
29Abnormality of dentin (HP:0010299)2.45566699
30Increased variability in muscle fiber diameter (HP:0003557)2.43812446
31Blue sclerae (HP:0000592)2.42822142
32Genu recurvatum (HP:0002816)2.35570007
33Mildly elevated creatine phosphokinase (HP:0008180)2.35482448
34Wide anterior fontanel (HP:0000260)2.33984261
35Wormian bones (HP:0002645)2.32157842
36Short hallux (HP:0010109)2.30654894
37Difficulty climbing stairs (HP:0003551)2.29246764
38Hyporeflexia of lower limbs (HP:0002600)2.28622915
39Hip contracture (HP:0003273)2.28319117
40Peritonitis (HP:0002586)2.24555861
41Overgrowth (HP:0001548)2.24454360
42Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.22874119
43Short 4th metacarpal (HP:0010044)2.22874119
44Vascular tortuosity (HP:0004948)2.22457807
45Mitral stenosis (HP:0001718)2.22173661
46Aneurysm (HP:0002617)2.22045132
47Short nail (HP:0001799)2.19426918
48Limb-girdle muscle atrophy (HP:0003797)2.19274251
49Abnormality of skeletal muscle fiber size (HP:0012084)2.18118606
50Lymphangioma (HP:0100764)2.17642307
51Aplasia/Hypoplasia of the hallux (HP:0008362)2.11843953
52Hyperextensible skin (HP:0000974)2.09495859
53Osteolytic defects of the hand bones (HP:0009699)2.07502240
54Osteolytic defects of the phalanges of the hand (HP:0009771)2.07502240
55Cupped ribs (HP:0000887)2.06551818
56Trismus (HP:0000211)2.05511413
57Mitral regurgitation (HP:0001653)2.05455658
58Mesomelia (HP:0003027)2.05096908
59Knee flexion contracture (HP:0006380)2.04897209
60Aortic regurgitation (HP:0001659)2.04481021
61Difficulty running (HP:0009046)2.01433295
62Abnormality of the 4th metacarpal (HP:0010012)1.98107338
63Arterial tortuosity (HP:0005116)1.97638119
64Spondylolisthesis (HP:0003302)1.97621029
65Coronal craniosynostosis (HP:0004440)1.95999243
66Limited hip movement (HP:0008800)1.95986223
67Camptodactyly of toe (HP:0001836)1.94185203
68Venous abnormality (HP:0002624)1.93777707
69Reduced subcutaneous adipose tissue (HP:0003758)1.93616555
70Hematochezia (HP:0002573)1.93593592
71Bell-shaped thorax (HP:0001591)1.91195085
72Joint laxity (HP:0001388)1.90677753
73Cardiovascular calcification (HP:0011915)1.90445340
74Round ear (HP:0100830)1.90204756
75Hypoplasia of the iris (HP:0007676)1.89578994
76Coxa vara (HP:0002812)1.89336734
77Thin bony cortex (HP:0002753)1.88763831
78Subacute progressive viral hepatitis (HP:0006572)1.87961704
79Scapular winging (HP:0003691)1.87901269
80Abnormal delivery (HP:0001787)1.87227178
81Abnormality of the acetabulum (HP:0003170)1.87224158
82Elbow flexion contracture (HP:0002987)1.86497935
83Rectal prolapse (HP:0002035)1.86482682
84Thin ribs (HP:0000883)1.85413934
85Aortic valve stenosis (HP:0001650)1.85191598
86Epiphyseal dysplasia (HP:0002656)1.84595619
87Acanthosis nigricans (HP:0000956)1.84453953
88Osteoarthritis (HP:0002758)1.84376795
89Ventricular tachycardia (HP:0004756)1.84023526
90Bronchomalacia (HP:0002780)1.83995500
91Vitreoretinal degeneration (HP:0000655)1.83924702
92Natal tooth (HP:0000695)1.83225089
93Broad long bones (HP:0005622)1.83165282
94Generalized amyotrophy (HP:0003700)1.82207965
95Vertebral arch anomaly (HP:0008438)1.80908992
96Venous insufficiency (HP:0005293)1.79877029
97Abnormality of the calf musculature (HP:0001430)1.79316420
98Abnormal vertebral ossification (HP:0100569)1.79310239
99Breech presentation (HP:0001623)1.78521543
100Exostoses (HP:0100777)1.76477414
101Ulnar bowing (HP:0003031)1.76064853
102Alopecia of scalp (HP:0002293)1.75779171
103Vertebral compression fractures (HP:0002953)1.74670939
104Lipoatrophy (HP:0100578)1.73938475
105Aplasia of the musculature (HP:0100854)1.73906824
106Abnormality of the distal phalanges of the toes (HP:0010182)1.73535162
107Aplasia involving bones of the upper limbs (HP:0009823)1.73337360
108Aplasia of the phalanges of the hand (HP:0009802)1.73337360
109Aplasia involving bones of the extremities (HP:0009825)1.73337360
110Bowel diverticulosis (HP:0005222)1.71702808
111Upper limb amyotrophy (HP:0009129)1.70992438
112Distal upper limb amyotrophy (HP:0007149)1.70992438
113Pulmonary artery stenosis (HP:0004415)1.70542733
114Abnormality of the anterior chamber (HP:0000593)1.70522067
115Biconcave vertebral bodies (HP:0004586)1.70378949
116Protruding ear (HP:0000411)1.69191460
117Ectopia lentis (HP:0001083)1.68851524
118Distal lower limb muscle weakness (HP:0009053)1.68704981
119Platyspondyly (HP:0000926)1.67468905
120Deviation of the hallux (HP:0010051)1.66856212
121Renal duplication (HP:0000075)1.66326471
122Flat acetabular roof (HP:0003180)1.65795293
123Nonimmune hydrops fetalis (HP:0001790)1.65424639
124Abnormal cartilage morphology (HP:0002763)1.64434220
125Striae distensae (HP:0001065)1.64248623
126Buphthalmos (HP:0000557)1.64181329
127Spinal cord compression (HP:0002176)1.60860269
128Abnormality of the umbilical cord (HP:0010881)1.56587838
129Abnormality of placental membranes (HP:0011409)1.56528640
130Amniotic constriction ring (HP:0009775)1.56528640
131Limb-girdle muscle weakness (HP:0003325)1.56061295
132Glucose intolerance (HP:0000833)1.53982546
133Vertebral clefting (HP:0008428)1.53467281
134White forelock (HP:0002211)1.53446706
135Abnormality of carpal bone ossification (HP:0006257)1.52819193
136Delayed cranial suture closure (HP:0000270)1.51803558
137Inguinal hernia (HP:0000023)1.50531864
138Flexion contracture of toe (HP:0005830)1.49802294
139Joint contractures involving the joints of the feet (HP:0100492)1.49802294

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS13.75582304
2DDR23.46569056
3TRIB33.42391311
4TTN3.26543612
5TIE13.05767905
6KDR2.87379826
7PDGFRA2.63337735
8EPHB22.62634314
9EPHA22.48462232
10NTRK12.43784744
11LATS22.40028958
12RIPK12.25189979
13SIK12.16934607
14FER2.14859378
15TGFBR22.08841647
16PKN22.01824288
17STK38L1.87123998
18DMPK1.75893372
19MAP3K31.75415802
20PTK61.68839372
21MET1.64291819
22STK31.58672249
23CDK81.53234705
24LRRK21.47998746
25PAK21.47045707
26PTK21.43023873
27TGFBR11.41710487
28PAK41.40324059
29MUSK1.38667860
30PDK21.37842398
31EPHA31.37598995
32PNCK1.30132884
33FGFR21.28432678
34MST1R1.22141454
35CAMK1D1.19495499
36NEK91.18157132
37FRK1.17844560
38PDK41.16028581
39PDK31.16028581
40NUAK11.11528578
41BMX1.11359950
42MYLK1.08527598
43TRPM71.07198537
44FGFR11.06218105
45FLT31.06003226
46PDGFRB1.04245984
47PTK2B1.04047549
48ERN11.04001103
49ILK1.03485597
50MTOR1.01612337
51ROCK10.98519989
52PAK30.94627449
53EPHB10.88971969
54PIK3CA0.88952025
55LMTK20.88919624
56CDK60.87063523
57FGFR30.86869945
58PRKD30.79683968
59FGFR40.79521487
60IRAK30.79266474
61ZAK0.78068976
62ICK0.77210550
63MOS0.76709424
64GSK3A0.74191596
65CAMK1G0.74010563
66STK100.72392499
67PRKD10.72222702
68EIF2AK30.69950449
69BCR0.67784942
70MAP2K10.67218683
71MELK0.66029411
72OBSCN0.65916349
73PRKG20.63942633
74WEE10.63635070
75MAP2K30.63622235
76STK240.62697953
77PLK20.62355495
78PAK60.60504809
79STK390.58814288
80RPS6KA40.58562557
81STK380.58255304
82BMPR1B0.57642520
83EIF2AK10.57563324
84ROCK20.53199730
85TSSK60.53129935
86PRKAA20.52171531
87CDK120.51581442
88WNK40.49784053
89RPS6KB20.49475010
90DYRK1B0.49323698
91INSR0.47169674
92ERBB30.47111577
93EEF2K0.46761025
94MAPKAPK30.45768544
95NEK10.44325265
96MAP2K20.43920784
97AKT20.43701442
98CAMK2D0.42448988
99BRSK10.42244812
100TESK10.41762698
101PRKD20.39279608
102MAPK120.39089256
103ARAF0.37370363
104TYRO30.37079580
105IGF1R0.36922280
106NME20.35551102
107MAPKAPK50.34827398
108PBK0.34658312
109LIMK10.34536367
110NLK0.33712000
111ERBB20.33425809
112CDK90.33035076
113TAOK20.32177425
114PLK30.32121688
115AKT30.31335763
116RET0.31065382
117VRK20.29742532
118BRSK20.29272689
119SRC0.28997388
120MAP3K80.28784179
121MST40.28279136
122CSNK1A1L0.28217784
123PRKCE0.28027683
124BUB10.27953742
125PIM20.27881105
126ERBB40.26966311
127PHKG20.26694633
128PHKG10.26694633
129MAPK70.25676970
130ABL20.24923393
131NEK20.24129748
132MARK30.23974783
133CDC42BPA0.23682586
134CAMK2G0.23220292
135DAPK30.22912208

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.37091070
2Focal adhesion_Homo sapiens_hsa045103.12371733
3Adherens junction_Homo sapiens_hsa045202.84356512
4Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.51619402
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.38019532
6Protein digestion and absorption_Homo sapiens_hsa049742.32864101
7Proteoglycans in cancer_Homo sapiens_hsa052052.28609254
8Small cell lung cancer_Homo sapiens_hsa052222.27184948
9Dilated cardiomyopathy_Homo sapiens_hsa054142.26372796
10TGF-beta signaling pathway_Homo sapiens_hsa043502.16345782
11* Hippo signaling pathway_Homo sapiens_hsa043902.07477898
12Basal cell carcinoma_Homo sapiens_hsa052172.04274459
13Amoebiasis_Homo sapiens_hsa051461.84104356
14Tight junction_Homo sapiens_hsa045301.81824841
15AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.79135053
16Hedgehog signaling pathway_Homo sapiens_hsa043401.70910410
17Bladder cancer_Homo sapiens_hsa052191.63872318
18PI3K-Akt signaling pathway_Homo sapiens_hsa041511.60104104
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.60079428
20Nitrogen metabolism_Homo sapiens_hsa009101.59882093
21PPAR signaling pathway_Homo sapiens_hsa033201.59406029
22MicroRNAs in cancer_Homo sapiens_hsa052061.58672749
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.55583790
24Glycosaminoglycan degradation_Homo sapiens_hsa005311.54246471
25Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.44129625
26Viral myocarditis_Homo sapiens_hsa054161.43525806
27Leukocyte transendothelial migration_Homo sapiens_hsa046701.40927850
28Fatty acid biosynthesis_Homo sapiens_hsa000611.36213077
29Fatty acid degradation_Homo sapiens_hsa000711.35535923
30Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.34897603
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.31447635
32Pathways in cancer_Homo sapiens_hsa052001.24364142
33Fatty acid metabolism_Homo sapiens_hsa012121.24208436
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19061437
35Melanoma_Homo sapiens_hsa052181.17356202
36Rap1 signaling pathway_Homo sapiens_hsa040151.16394750
37Regulation of actin cytoskeleton_Homo sapiens_hsa048101.15981071
38Circadian rhythm_Homo sapiens_hsa047101.15742595
39Prostate cancer_Homo sapiens_hsa052151.14158111
40Propanoate metabolism_Homo sapiens_hsa006401.08900139
41Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.01832013
42Prion diseases_Homo sapiens_hsa050200.99857788
43Adipocytokine signaling pathway_Homo sapiens_hsa049200.99561226
44Malaria_Homo sapiens_hsa051440.99407085
45Renal cell carcinoma_Homo sapiens_hsa052110.99292034
46N-Glycan biosynthesis_Homo sapiens_hsa005100.99256165
47Insulin resistance_Homo sapiens_hsa049310.98450841
48Chronic myeloid leukemia_Homo sapiens_hsa052200.97002125
49AMPK signaling pathway_Homo sapiens_hsa041520.96324665
50Notch signaling pathway_Homo sapiens_hsa043300.94643469
51HIF-1 signaling pathway_Homo sapiens_hsa040660.94523141
52Wnt signaling pathway_Homo sapiens_hsa043100.94004418
53Protein export_Homo sapiens_hsa030600.93197303
54Central carbon metabolism in cancer_Homo sapiens_hsa052300.92352682
55Dorso-ventral axis formation_Homo sapiens_hsa043200.86903146
56p53 signaling pathway_Homo sapiens_hsa041150.85939909
57Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85650472
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.81931164
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.80987332
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.79781618
61Toxoplasmosis_Homo sapiens_hsa051450.79639346
62Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78624570
63HTLV-I infection_Homo sapiens_hsa051660.78070132
64Thyroid hormone signaling pathway_Homo sapiens_hsa049190.77482025
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.77463377
66Lysine degradation_Homo sapiens_hsa003100.77229391
67Axon guidance_Homo sapiens_hsa043600.76857013
68Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76629065
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76459688
70Melanogenesis_Homo sapiens_hsa049160.74689954
71Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.72622622
72Endometrial cancer_Homo sapiens_hsa052130.70697245
73Vibrio cholerae infection_Homo sapiens_hsa051100.70421081
74Thyroid cancer_Homo sapiens_hsa052160.69712214
75Pancreatic cancer_Homo sapiens_hsa052120.69058309
76Platelet activation_Homo sapiens_hsa046110.67280894
77Pyruvate metabolism_Homo sapiens_hsa006200.66626621
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.66494475
79Complement and coagulation cascades_Homo sapiens_hsa046100.65346742
80FoxO signaling pathway_Homo sapiens_hsa040680.65192840
81Steroid biosynthesis_Homo sapiens_hsa001000.64826658
82Glioma_Homo sapiens_hsa052140.60791839
83Fatty acid elongation_Homo sapiens_hsa000620.60067082
84Galactose metabolism_Homo sapiens_hsa000520.59409699
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59264793
86Ovarian steroidogenesis_Homo sapiens_hsa049130.59225078
87Ras signaling pathway_Homo sapiens_hsa040140.56541050
88Carbon metabolism_Homo sapiens_hsa012000.56495378
89Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55675040
90Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55003017
91Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.54814763
92Insulin signaling pathway_Homo sapiens_hsa049100.53971872
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53714703
94Biosynthesis of amino acids_Homo sapiens_hsa012300.52400604
95mTOR signaling pathway_Homo sapiens_hsa041500.52192846
96Bile secretion_Homo sapiens_hsa049760.51657595
97Sulfur metabolism_Homo sapiens_hsa009200.51616658
98Renin-angiotensin system_Homo sapiens_hsa046140.51096392
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50633177
100Colorectal cancer_Homo sapiens_hsa052100.49773094
101Estrogen signaling pathway_Homo sapiens_hsa049150.48581464
102Glucagon signaling pathway_Homo sapiens_hsa049220.48147727
103cGMP-PKG signaling pathway_Homo sapiens_hsa040220.47201642
104Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.47198682
105Mineral absorption_Homo sapiens_hsa049780.46604652
106Proteasome_Homo sapiens_hsa030500.45451944
107Sulfur relay system_Homo sapiens_hsa041220.44920237
108Pentose phosphate pathway_Homo sapiens_hsa000300.44592751
109Renin secretion_Homo sapiens_hsa049240.44166124
110Arginine and proline metabolism_Homo sapiens_hsa003300.44077379
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43686264
112Vascular smooth muscle contraction_Homo sapiens_hsa042700.40954925
113Caffeine metabolism_Homo sapiens_hsa002320.40940155
114Starch and sucrose metabolism_Homo sapiens_hsa005000.40816103
115Arginine biosynthesis_Homo sapiens_hsa002200.40747841
116Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40476485
117Gap junction_Homo sapiens_hsa045400.40336405
118VEGF signaling pathway_Homo sapiens_hsa043700.38781753
119Selenocompound metabolism_Homo sapiens_hsa004500.38518276
120Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38248097
121Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.35475353
122Endocytosis_Homo sapiens_hsa041440.35207634
123Glutathione metabolism_Homo sapiens_hsa004800.35057261
124beta-Alanine metabolism_Homo sapiens_hsa004100.34715067
125TNF signaling pathway_Homo sapiens_hsa046680.33737520
126Sphingolipid metabolism_Homo sapiens_hsa006000.33615676
127Thyroid hormone synthesis_Homo sapiens_hsa049180.32740983
128Vitamin B6 metabolism_Homo sapiens_hsa007500.32691574
129Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.31984506
130Salivary secretion_Homo sapiens_hsa049700.31960534
131Phospholipase D signaling pathway_Homo sapiens_hsa040720.31090887
132Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.29043095
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27026379
134Transcriptional misregulation in cancer_Homo sapiens_hsa052020.26704876

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