

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of T cell mediated immunity (GO:0002710) | 9.97837736 |
| 2 | negative regulation of interleukin-2 production (GO:0032703) | 8.39260860 |
| 3 | interferon-gamma production (GO:0032609) | 8.29064161 |
| 4 | regulation of RIG-I signaling pathway (GO:0039535) | 8.00107133 |
| 5 | positive regulation of T-helper 1 type immune response (GO:0002827) | 7.96662982 |
| 6 | lymphocyte chemotaxis (GO:0048247) | 7.73740103 |
| 7 | positive regulation of type 2 immune response (GO:0002830) | 7.47479464 |
| 8 | regulation of lymphocyte chemotaxis (GO:1901623) | 7.34279463 |
| 9 | regulation of T cell cytokine production (GO:0002724) | 7.20851726 |
| 10 | positive regulation of transforming growth factor beta production (GO:0071636) | 7.17292458 |
| 11 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 7.05148351 |
| 12 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 6.75430562 |
| 13 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 6.74775342 |
| 14 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 6.47080741 |
| 15 | negative regulation of cytokine production involved in immune response (GO:0002719) | 6.32291001 |
| 16 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 6.28615814 |
| 17 | regulation of T-helper 1 type immune response (GO:0002825) | 6.15941092 |
| 18 | positive regulation of hormone biosynthetic process (GO:0046886) | 6.14967346 |
| 19 | negative regulation of alpha-beta T cell activation (GO:0046636) | 6.04128586 |
| 20 | cellular response to interleukin-4 (GO:0071353) | 5.95229451 |
| 21 | regulation of T cell mediated cytotoxicity (GO:0001914) | 5.82517540 |
| 22 | positive regulation of cell killing (GO:0031343) | 5.58206208 |
| 23 | positive regulation of neutrophil migration (GO:1902624) | 5.53600749 |
| 24 | positive regulation of neutrophil chemotaxis (GO:0090023) | 5.53600749 |
| 25 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 5.44294277 |
| 26 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 5.44090126 |
| 27 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 5.41050978 |
| 28 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 5.28908378 |
| 29 | regulation of alpha-beta T cell proliferation (GO:0046640) | 5.21101624 |
| 30 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 5.14652348 |
| 31 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 5.12203200 |
| 32 | response to interleukin-4 (GO:0070670) | 4.97732216 |
| 33 | positive regulation of T cell migration (GO:2000406) | 4.96461730 |
| 34 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 4.93679300 |
| 35 | negative regulation of heart rate (GO:0010459) | 4.93320427 |
| 36 | positive regulation of granulocyte chemotaxis (GO:0071624) | 4.92562940 |
| 37 | regulation of cell killing (GO:0031341) | 4.86064169 |
| 38 | positive regulation of lymphocyte migration (GO:2000403) | 4.78808538 |
| 39 | lymphocyte migration (GO:0072676) | 4.75785228 |
| 40 | activated T cell proliferation (GO:0050798) | 4.68077781 |
| 41 | negative regulation of adaptive immune response (GO:0002820) | 4.55429208 |
| 42 | positive regulation of hormone metabolic process (GO:0032352) | 4.53296090 |
| 43 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 4.51483089 |
| 44 | positive regulation of B cell mediated immunity (GO:0002714) | 4.51483089 |
| 45 | positive regulation of interleukin-10 production (GO:0032733) | 4.47525909 |
| 46 | positive regulation of release of sequestered calcium ion into cytosol (GO:0051281) | 4.42210961 |
| 47 | positive regulation of fibroblast migration (GO:0010763) | 4.40803404 |
| 48 | positive regulation of immunoglobulin production (GO:0002639) | 4.33397039 |
| 49 | positive regulation of glycolytic process (GO:0045821) | 4.31546129 |
| 50 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.27049476 |
| 51 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.27049476 |
| 52 | regulation of neutrophil chemotaxis (GO:0090022) | 4.26298891 |
| 53 | regulation of neutrophil migration (GO:1902622) | 4.26298891 |
| 54 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 4.25562819 |
| 55 | regulation of T cell migration (GO:2000404) | 4.24294487 |
| 56 | mRNA cleavage (GO:0006379) | 4.23070653 |
| 57 | positive regulation of T cell mediated immunity (GO:0002711) | 4.20772327 |
| 58 | cellular response to interleukin-15 (GO:0071350) | 4.15775525 |
| 59 | positive regulation of protein sumoylation (GO:0033235) | 4.14803398 |
| 60 | regulation of type 2 immune response (GO:0002828) | 4.13181092 |
| 61 | negative regulation of leukocyte mediated immunity (GO:0002704) | 4.07591427 |
| 62 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 4.01841118 |
| 63 | response to interleukin-15 (GO:0070672) | 3.94903953 |
| 64 | regulation of transforming growth factor beta production (GO:0071634) | 3.81082808 |
| 65 | negative regulation of sequestering of calcium ion (GO:0051283) | 3.75959173 |
| 66 | release of sequestered calcium ion into cytosol (GO:0051209) | 3.75959173 |
| 67 | regulation of glomerular filtration (GO:0003093) | 3.68655362 |
| 68 | L-fucose catabolic process (GO:0042355) | 3.63356038 |
| 69 | fucose catabolic process (GO:0019317) | 3.63356038 |
| 70 | L-fucose metabolic process (GO:0042354) | 3.63356038 |
| 71 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.60756063 |
| 72 | regulation of interleukin-2 production (GO:0032663) | 3.60435758 |
| 73 | positive regulation of cytokine production involved in immune response (GO:0002720) | 3.52428930 |
| 74 | NIK/NF-kappaB signaling (GO:0038061) | 3.51345997 |
| 75 | regulation of lymphocyte migration (GO:2000401) | 3.48874872 |
| 76 | regulation of sequestering of calcium ion (GO:0051282) | 3.46485940 |
| 77 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.45386192 |
| 78 | mRNA transcription (GO:0009299) | 3.37519269 |
| 79 | regulation of T cell mediated immunity (GO:0002709) | 3.35875082 |
| 80 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.34960914 |
| 81 | negative regulation of interferon-gamma production (GO:0032689) | 3.34238383 |
| 82 | cellular response to nicotine (GO:0071316) | 3.32596482 |
| 83 | regulation of interleukin-10 production (GO:0032653) | 3.32070563 |
| 84 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.29473648 |
| 85 | mast cell degranulation (GO:0043303) | 3.28469253 |
| 86 | mast cell activation involved in immune response (GO:0002279) | 3.28469253 |
| 87 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.27892308 |
| 88 | regulation of B cell mediated immunity (GO:0002712) | 3.23531439 |
| 89 | regulation of immunoglobulin production (GO:0002637) | 3.22647625 |
| 90 | nerve growth factor signaling pathway (GO:0038180) | 3.19423391 |
| 91 | cytidine metabolic process (GO:0046087) | 3.17081349 |
| 92 | cytidine catabolic process (GO:0006216) | 3.17081349 |
| 93 | cytidine deamination (GO:0009972) | 3.17081349 |
| 94 | regulation of granulocyte chemotaxis (GO:0071622) | 3.14612078 |
| 95 | positive regulation of erythrocyte differentiation (GO:0045648) | 3.13948008 |
| 96 | DNA deamination (GO:0045006) | 3.11574328 |
| 97 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 11.1810950 |
| 98 | positive regulation of T cell cytokine production (GO:0002726) | 11.1411497 |
| 99 | regulation of T cell chemotaxis (GO:0010819) | 10.3542423 |
| 100 | positive regulation of T cell chemotaxis (GO:0010820) | 10.3542423 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 8.47427192 |
| 2 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 5.99355505 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.18425162 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.99496980 |
| 5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.50689358 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.42751444 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.83869404 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.67973647 |
| 9 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 3.42446332 |
| 10 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 3.13614853 |
| 11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.09872006 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.84210989 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.74312507 |
| 14 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.72401798 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.57032260 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.53715964 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.50909618 |
| 18 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.24147477 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.15477715 |
| 20 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.13567945 |
| 21 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.11015575 |
| 22 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.99456840 |
| 23 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89048131 |
| 24 | * MYB_26560356_Chip-Seq_TH2_Human | 1.74904907 |
| 25 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.70527356 |
| 26 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.69896044 |
| 27 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.62202991 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.60102524 |
| 29 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.57078617 |
| 30 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.55581758 |
| 31 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.55283042 |
| 32 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.54368097 |
| 33 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.53544289 |
| 34 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.51538832 |
| 35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.37883078 |
| 36 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37758466 |
| 37 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.33061194 |
| 38 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.25928687 |
| 39 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.24168715 |
| 40 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.22703555 |
| 41 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.21986985 |
| 42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.18073814 |
| 43 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.15918569 |
| 44 | MYB_26560356_Chip-Seq_TH1_Human | 1.13858575 |
| 45 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.13216331 |
| 46 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.10280997 |
| 47 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.07623307 |
| 48 | MAF_26560356_Chip-Seq_TH1_Human | 1.05543161 |
| 49 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.05436107 |
| 50 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.04667726 |
| 51 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.04378791 |
| 52 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.03093888 |
| 53 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.03033433 |
| 54 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02636131 |
| 55 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.02133018 |
| 56 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.02001492 |
| 57 | MAF_26560356_Chip-Seq_TH2_Human | 1.01076544 |
| 58 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.00975341 |
| 59 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.00265736 |
| 60 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94722039 |
| 61 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94537032 |
| 62 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91256557 |
| 63 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.89667434 |
| 64 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.89570594 |
| 65 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.89307337 |
| 66 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.87629295 |
| 67 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.87228111 |
| 68 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.87178123 |
| 69 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.86826227 |
| 70 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.86167421 |
| 71 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.86012630 |
| 72 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.85487195 |
| 73 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.85460534 |
| 74 | * RBPJ_21746931_ChIP-Seq_IB4_Human | 0.84981133 |
| 75 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.82551987 |
| 76 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.82141723 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.81038830 |
| 78 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.80121784 |
| 79 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.79080490 |
| 80 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.78834323 |
| 81 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.78798322 |
| 82 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.78185711 |
| 83 | * GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.78076381 |
| 84 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.77144568 |
| 85 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76967693 |
| 86 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.76883332 |
| 87 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.76812930 |
| 88 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.75824265 |
| 89 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73911905 |
| 90 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.73068400 |
| 91 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.72999390 |
| 92 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.72578078 |
| 93 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.72125868 |
| 94 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.71625464 |
| 95 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.71598730 |
| 96 | UTX_26944678_Chip-Seq_JUKART_Human | 0.70326750 |
| 97 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.70264236 |
| 98 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.69591167 |
| 99 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.68981395 |
| 100 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.68629976 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002006_tumorigenesis | 4.79319110 |
| 2 | MP0005310_abnormal_salivary_gland | 4.21286519 |
| 3 | MP0005671_abnormal_response_to | 3.88358353 |
| 4 | MP0001790_abnormal_immune_system | 3.87279711 |
| 5 | MP0005387_immune_system_phenotype | 3.87279711 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 3.56338375 |
| 7 | MP0003303_peritoneal_inflammation | 3.26773336 |
| 8 | MP0004381_abnormal_hair_follicle | 3.20938025 |
| 9 | MP0000372_irregular_coat_pigmentation | 3.01982970 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.69228265 |
| 11 | MP0003763_abnormal_thymus_physiology | 2.63165175 |
| 12 | MP0001800_abnormal_humoral_immune | 2.48482495 |
| 13 | MP0002138_abnormal_hepatobiliary_system | 2.45563549 |
| 14 | MP0005075_abnormal_melanosome_morpholog | 2.31913318 |
| 15 | MP0002723_abnormal_immune_serum | 2.21391183 |
| 16 | MP0003448_altered_tumor_morphology | 2.15211906 |
| 17 | MP0003724_increased_susceptibility_to | 2.14996452 |
| 18 | MP0000685_abnormal_immune_system | 2.11322396 |
| 19 | MP0002420_abnormal_adaptive_immunity | 2.10971351 |
| 20 | MP0001835_abnormal_antigen_presentation | 2.05054524 |
| 21 | MP0001819_abnormal_immune_cell | 2.04560593 |
| 22 | MP0001853_heart_inflammation | 1.91419657 |
| 23 | MP0002452_abnormal_antigen_presenting | 1.90719305 |
| 24 | MP0004947_skin_inflammation | 1.81480038 |
| 25 | MP0003646_muscle_fatigue | 1.79839428 |
| 26 | MP0004510_myositis | 1.77173571 |
| 27 | MP0006082_CNS_inflammation | 1.74967009 |
| 28 | MP0003436_decreased_susceptibility_to | 1.72587746 |
| 29 | MP0001873_stomach_inflammation | 1.71202011 |
| 30 | MP0005451_abnormal_body_composition | 1.71056703 |
| 31 | MP0005025_abnormal_response_to | 1.70117258 |
| 32 | MP0000613_abnormal_salivary_gland | 1.69485207 |
| 33 | MP0001881_abnormal_mammary_gland | 1.66748589 |
| 34 | MP0001502_abnormal_circadian_rhythm | 1.61746162 |
| 35 | MP0003786_premature_aging | 1.61445927 |
| 36 | MP0002166_altered_tumor_susceptibility | 1.61432520 |
| 37 | MP0002398_abnormal_bone_marrow | 1.56854636 |
| 38 | MP0009785_altered_susceptibility_to | 1.55156980 |
| 39 | MP0002796_impaired_skin_barrier | 1.51189096 |
| 40 | MP0003866_abnormal_defecation | 1.49440163 |
| 41 | MP0000716_abnormal_immune_system | 1.48236395 |
| 42 | MP0002396_abnormal_hematopoietic_system | 1.46854251 |
| 43 | MP0001845_abnormal_inflammatory_respons | 1.40596158 |
| 44 | MP0000689_abnormal_spleen_morphology | 1.35902313 |
| 45 | MP0006276_abnormal_autonomic_nervous | 1.35770597 |
| 46 | MP0002254_reproductive_system_inflammat | 1.35507959 |
| 47 | MP0008260_abnormal_autophagy | 1.34590193 |
| 48 | MP0002722_abnormal_immune_system | 1.34055393 |
| 49 | MP0000703_abnormal_thymus_morphology | 1.31675115 |
| 50 | MP0002419_abnormal_innate_immunity | 1.31346221 |
| 51 | MP0002148_abnormal_hypersensitivity_rea | 1.30868614 |
| 52 | MP0003453_abnormal_keratinocyte_physiol | 1.30039268 |
| 53 | MP0001958_emphysema | 1.29006301 |
| 54 | MP0002429_abnormal_blood_cell | 1.24450433 |
| 55 | MP0005085_abnormal_gallbladder_physiolo | 1.24191176 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.21335383 |
| 57 | MP0002405_respiratory_system_inflammati | 1.20258595 |
| 58 | MP0008469_abnormal_protein_level | 1.17670639 |
| 59 | MP0000627_abnormal_mammary_gland | 1.16070150 |
| 60 | MP0003045_fibrosis | 1.10211134 |
| 61 | MP0002653_abnormal_ependyma_morphology | 1.09818464 |
| 62 | MP0000013_abnormal_adipose_tissue | 1.07663183 |
| 63 | MP0006035_abnormal_mitochondrial_morpho | 1.07501603 |
| 64 | MP0000358_abnormal_cell_content/ | 1.06573482 |
| 65 | MP0000609_abnormal_liver_physiology | 1.00550821 |
| 66 | MP0002136_abnormal_kidney_physiology | 1.00528486 |
| 67 | MP0000569_abnormal_digit_pigmentation | 0.96280138 |
| 68 | MP0010155_abnormal_intestine_physiology | 0.96092268 |
| 69 | MP0009763_increased_sensitivity_to | 0.90679134 |
| 70 | MP0008872_abnormal_physiological_respon | 0.87785683 |
| 71 | MP0002877_abnormal_melanocyte_morpholog | 0.87437618 |
| 72 | MP0001661_extended_life_span | 0.85969386 |
| 73 | MP0004484_altered_response_of | 0.85221703 |
| 74 | MP0000015_abnormal_ear_pigmentation | 0.84335119 |
| 75 | MP0003172_abnormal_lysosome_physiology | 0.84280467 |
| 76 | MP0006036_abnormal_mitochondrial_physio | 0.81968667 |
| 77 | MP0004142_abnormal_muscle_tone | 0.81815335 |
| 78 | MP0000749_muscle_degeneration | 0.81778049 |
| 79 | MP0003936_abnormal_reproductive_system | 0.78226653 |
| 80 | MP0003959_abnormal_lean_body | 0.77712311 |
| 81 | MP0002019_abnormal_tumor_incidence | 0.76994893 |
| 82 | MP0002970_abnormal_white_adipose | 0.74982168 |
| 83 | MP0002971_abnormal_brown_adipose | 0.72736621 |
| 84 | MP0001533_abnormal_skeleton_physiology | 0.71857537 |
| 85 | MP0002909_abnormal_adrenal_gland | 0.68140454 |
| 86 | MP0004742_abnormal_vestibular_system | 0.66919076 |
| 87 | MP0002132_abnormal_respiratory_system | 0.60568982 |
| 88 | MP0005501_abnormal_skin_physiology | 0.59799251 |
| 89 | MP0001663_abnormal_digestive_system | 0.59010743 |
| 90 | MP0002933_joint_inflammation | 0.54615486 |
| 91 | MP0001664_abnormal_digestion | 0.53387398 |
| 92 | MP0003693_abnormal_embryo_hatching | 0.53178183 |
| 93 | MP0005332_abnormal_amino_acid | 0.53050518 |
| 94 | MP0003828_pulmonary_edema | 0.52319317 |
| 95 | MP0002067_abnormal_sensory_capabilities | 0.52133981 |
| 96 | MP0009745_abnormal_behavioral_response | 0.51928419 |
| 97 | MP0005452_abnormal_adipose_tissue | 0.51597140 |
| 98 | MP0005167_abnormal_blood-brain_barrier | 0.50016455 |
| 99 | MP0002163_abnormal_gland_morphology | 0.47654578 |
| 100 | MP0005551_abnormal_eye_electrophysiolog | 0.46264986 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Retrobulbar optic neuritis (HP:0100654) | 9.14714134 |
| 2 | Optic neuritis (HP:0100653) | 9.14714134 |
| 3 | Orchitis (HP:0100796) | 8.03874710 |
| 4 | Myositis (HP:0100614) | 7.20072315 |
| 5 | Keratoconjunctivitis sicca (HP:0001097) | 6.17258341 |
| 6 | Abnormality of the labia minora (HP:0012880) | 5.97611306 |
| 7 | Keratoconjunctivitis (HP:0001096) | 5.71999019 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 4.79308660 |
| 9 | Encephalitis (HP:0002383) | 4.65026215 |
| 10 | Slow saccadic eye movements (HP:0000514) | 4.55041643 |
| 11 | Keratitis (HP:0000491) | 3.94490410 |
| 12 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.85136855 |
| 13 | Pulmonary infiltrates (HP:0002113) | 3.79854145 |
| 14 | Hypoproteinemia (HP:0003075) | 3.65024081 |
| 15 | T lymphocytopenia (HP:0005403) | 3.52073446 |
| 16 | Recurrent cutaneous fungal infections (HP:0011370) | 3.41508959 |
| 17 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.41508959 |
| 18 | Hypoplastic ischia (HP:0003175) | 3.33880144 |
| 19 | Gangrene (HP:0100758) | 3.28086646 |
| 20 | Arterial thrombosis (HP:0004420) | 3.25960130 |
| 21 | Orthostatic hypotension (HP:0001278) | 3.18448579 |
| 22 | Abnormality of T cell number (HP:0011839) | 3.16571440 |
| 23 | Hemoptysis (HP:0002105) | 3.14417416 |
| 24 | Impaired smooth pursuit (HP:0007772) | 3.00499426 |
| 25 | Anorexia (HP:0002039) | 2.94470833 |
| 26 | Panhypogammaglobulinemia (HP:0003139) | 2.93186831 |
| 27 | Abnormality of T cells (HP:0002843) | 2.90811157 |
| 28 | Abnormality of lateral ventricle (HP:0030047) | 2.82893563 |
| 29 | Pulmonary embolism (HP:0002204) | 2.80929050 |
| 30 | Sparse scalp hair (HP:0002209) | 2.80387119 |
| 31 | Dysautonomia (HP:0002459) | 2.79725324 |
| 32 | Abnormality of the ischium (HP:0003174) | 2.76216957 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.72144372 |
| 34 | IgG deficiency (HP:0004315) | 2.63866091 |
| 35 | Abnormality of saccadic eye movements (HP:0000570) | 2.55680303 |
| 36 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.55522433 |
| 37 | Hypoplastic nipples (HP:0002557) | 2.53932403 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.53658090 |
| 39 | Molar tooth sign on MRI (HP:0002419) | 2.53658090 |
| 40 | Acne (HP:0001061) | 2.52249119 |
| 41 | Arthropathy (HP:0003040) | 2.49842367 |
| 42 | Prominent nose (HP:0000448) | 2.46835630 |
| 43 | Meningitis (HP:0001287) | 2.46076021 |
| 44 | Cerebral hypomyelination (HP:0006808) | 2.44994219 |
| 45 | Abnormality of the endocardium (HP:0004306) | 2.41905446 |
| 46 | Abnormality of the clitoris (HP:0000056) | 2.38969786 |
| 47 | Abnormality of T cell physiology (HP:0011840) | 2.38301965 |
| 48 | Clitoromegaly (HP:0000057) | 2.38287955 |
| 49 | Anhidrosis (HP:0000970) | 2.37582262 |
| 50 | Abnormality of the pleura (HP:0002103) | 2.30888052 |
| 51 | Chronic diarrhea (HP:0002028) | 2.21454199 |
| 52 | Agammaglobulinemia (HP:0004432) | 2.19289585 |
| 53 | Genetic anticipation (HP:0003743) | 2.18328926 |
| 54 | Menstrual irregularities (HP:0000858) | 2.18185044 |
| 55 | Abnormality of oral frenula (HP:0000190) | 2.16486239 |
| 56 | Vasculitis (HP:0002633) | 2.14252681 |
| 57 | Dyschromatopsia (HP:0007641) | 2.12242837 |
| 58 | Abnormality of placental membranes (HP:0011409) | 2.10832292 |
| 59 | Amniotic constriction ring (HP:0009775) | 2.10832292 |
| 60 | Gaze-evoked nystagmus (HP:0000640) | 2.09726560 |
| 61 | Abnormality of the labia (HP:0000058) | 2.09049950 |
| 62 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.09007270 |
| 63 | Oligodactyly (hands) (HP:0001180) | 2.05785441 |
| 64 | Abnormality of the pericardium (HP:0001697) | 2.05667317 |
| 65 | Horizontal nystagmus (HP:0000666) | 2.04634860 |
| 66 | Fetal akinesia sequence (HP:0001989) | 2.01185958 |
| 67 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.00068846 |
| 68 | Type I transferrin isoform profile (HP:0003642) | 1.98694662 |
| 69 | Supranuclear gaze palsy (HP:0000605) | 1.98668721 |
| 70 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.97588435 |
| 71 | Recurrent fungal infections (HP:0002841) | 1.95162566 |
| 72 | Recurrent corneal erosions (HP:0000495) | 1.94332371 |
| 73 | Tubular atrophy (HP:0000092) | 1.92808757 |
| 74 | Joint swelling (HP:0001386) | 1.92671687 |
| 75 | Progressive external ophthalmoplegia (HP:0000590) | 1.91396997 |
| 76 | Oligodontia (HP:0000677) | 1.90608356 |
| 77 | Pheochromocytoma (HP:0002666) | 1.90428770 |
| 78 | Hyperlipoproteinemia (HP:0010980) | 1.89063156 |
| 79 | Severe combined immunodeficiency (HP:0004430) | 1.88865362 |
| 80 | Polyneuropathy (HP:0001271) | 1.88783891 |
| 81 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.87718401 |
| 82 | Abnormality of intracranial pressure (HP:0012640) | 1.86938668 |
| 83 | Increased intracranial pressure (HP:0002516) | 1.86938668 |
| 84 | Short tibia (HP:0005736) | 1.85056655 |
| 85 | Cutaneous melanoma (HP:0012056) | 1.82898630 |
| 86 | Pancreatitis (HP:0001733) | 1.82042721 |
| 87 | Glomerulopathy (HP:0100820) | 1.81636853 |
| 88 | Abnormality of DNA repair (HP:0003254) | 1.78713278 |
| 89 | Microvesicular hepatic steatosis (HP:0001414) | 1.77971886 |
| 90 | Autoamputation (HP:0001218) | 1.77623858 |
| 91 | Abnormal protein glycosylation (HP:0012346) | 1.76994201 |
| 92 | Abnormal glycosylation (HP:0012345) | 1.76994201 |
| 93 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.76994201 |
| 94 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.76994201 |
| 95 | Mediastinal lymphadenopathy (HP:0100721) | 1.76563400 |
| 96 | Neuroendocrine neoplasm (HP:0100634) | 1.72964362 |
| 97 | Chorioretinal atrophy (HP:0000533) | 1.70359779 |
| 98 | Fair hair (HP:0002286) | 1.70206729 |
| 99 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.69972073 |
| 100 | Thrombophlebitis (HP:0004418) | 1.68643626 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NEK9 | 6.07161967 |
| 2 | FES | 4.68750707 |
| 3 | TAOK1 | 4.07342932 |
| 4 | MAP3K11 | 3.94732473 |
| 5 | MAPKAPK3 | 3.83674440 |
| 6 | TAOK2 | 3.72533899 |
| 7 | NTRK1 | 3.57243358 |
| 8 | NLK | 3.55073463 |
| 9 | MATK | 3.23752677 |
| 10 | MAP3K3 | 3.19834842 |
| 11 | MAP2K3 | 3.17733167 |
| 12 | TXK | 2.90526790 |
| 13 | CSK | 1.92694986 |
| 14 | DAPK1 | 1.80422695 |
| 15 | SRPK1 | 1.79024411 |
| 16 | MAP4K1 | 1.77395215 |
| 17 | JAK3 | 1.76498292 |
| 18 | ALK | 1.59962496 |
| 19 | TSSK6 | 1.59198414 |
| 20 | TLK1 | 1.57127333 |
| 21 | FER | 1.47418022 |
| 22 | TAOK3 | 1.42943304 |
| 23 | EPHA3 | 1.41819692 |
| 24 | MAP3K1 | 1.36732160 |
| 25 | PIK3CG | 1.15458157 |
| 26 | TYRO3 | 1.12762289 |
| 27 | PINK1 | 1.10346427 |
| 28 | MAP2K6 | 1.08446699 |
| 29 | LCK | 0.95846450 |
| 30 | CSNK1A1L | 0.94102534 |
| 31 | CAMKK2 | 0.92237059 |
| 32 | CSNK1G3 | 0.91455174 |
| 33 | MAP3K5 | 0.90028279 |
| 34 | EPHB1 | 0.88842369 |
| 35 | CSNK1G2 | 0.88224345 |
| 36 | MAPK11 | 0.87528175 |
| 37 | FGFR4 | 0.86903160 |
| 38 | PRKCQ | 0.85307634 |
| 39 | MAPKAPK2 | 0.84667944 |
| 40 | WNK4 | 0.82596736 |
| 41 | MAP3K14 | 0.79506925 |
| 42 | GRK7 | 0.75877113 |
| 43 | MAP3K12 | 0.73457485 |
| 44 | NME1 | 0.73317461 |
| 45 | ITK | 0.70962336 |
| 46 | ZAK | 0.67164730 |
| 47 | SYK | 0.66633320 |
| 48 | PHKG2 | 0.66344304 |
| 49 | PHKG1 | 0.66344304 |
| 50 | BTK | 0.63372786 |
| 51 | ADRBK2 | 0.59859928 |
| 52 | IKBKB | 0.58102930 |
| 53 | MAP4K2 | 0.57912727 |
| 54 | CSNK1G1 | 0.57705277 |
| 55 | EIF2AK3 | 0.56177824 |
| 56 | EIF2AK2 | 0.55852927 |
| 57 | ERN1 | 0.54041689 |
| 58 | ERBB2 | 0.52818562 |
| 59 | CLK1 | 0.52310905 |
| 60 | JAK1 | 0.51193568 |
| 61 | NUAK1 | 0.50012758 |
| 62 | YES1 | 0.49180179 |
| 63 | CAMKK1 | 0.48475597 |
| 64 | IKBKE | 0.46765029 |
| 65 | LYN | 0.43435502 |
| 66 | PIK3CA | 0.42770241 |
| 67 | KIT | 0.42317709 |
| 68 | TGFBR2 | 0.41430028 |
| 69 | HCK | 0.39002265 |
| 70 | INSR | 0.38532434 |
| 71 | MARK3 | 0.38422659 |
| 72 | IRAK1 | 0.33546641 |
| 73 | DMPK | 0.32583954 |
| 74 | VRK2 | 0.30577472 |
| 75 | PTK2B | 0.26362994 |
| 76 | JAK2 | 0.25220269 |
| 77 | RPS6KB1 | 0.24506024 |
| 78 | IGF1R | 0.24207495 |
| 79 | NEK1 | 0.22735794 |
| 80 | CAMK2D | 0.20798825 |
| 81 | CHEK2 | 0.20655938 |
| 82 | PDGFRB | 0.20076496 |
| 83 | FGFR3 | 0.19936470 |
| 84 | CSF1R | 0.19308568 |
| 85 | ACVR1B | 0.19034423 |
| 86 | STK10 | 0.18944127 |
| 87 | CAMK2G | 0.18319424 |
| 88 | PTK6 | 0.16716135 |
| 89 | BUB1 | 0.16388300 |
| 90 | GRK6 | 0.16351710 |
| 91 | CSNK2A1 | 0.15953694 |
| 92 | TNK2 | 0.14491737 |
| 93 | EIF2AK1 | 0.14326390 |
| 94 | CSNK1D | 0.13951975 |
| 95 | CHUK | 0.13044337 |
| 96 | ATR | 0.12931480 |
| 97 | CSNK1E | 0.12770503 |
| 98 | GSK3A | 0.12512077 |
| 99 | PRKCH | 0.12061160 |
| 100 | TBK1 | 0.12000193 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.73022533 |
| 2 | Antigen processing and presentation_Homo sapiens_hsa04612 | 4.11002856 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.98065594 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.57947600 |
| 5 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.26817097 |
| 6 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.04075693 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.86430021 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.76244419 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.59270910 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.56358246 |
| 11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.55675631 |
| 12 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.47452200 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.39785319 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.28343622 |
| 15 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 2.23404522 |
| 16 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 2.22436991 |
| 17 | Malaria_Homo sapiens_hsa05144 | 2.09733988 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.00107657 |
| 19 | Measles_Homo sapiens_hsa05162 | 1.73447762 |
| 20 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.70539288 |
| 21 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.57620062 |
| 22 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.52680536 |
| 23 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.32061680 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.28674073 |
| 25 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.28562141 |
| 26 | Protein export_Homo sapiens_hsa03060 | 1.22991149 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.19876120 |
| 28 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.16929875 |
| 29 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.13164424 |
| 30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.08796051 |
| 31 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.04167915 |
| 32 | Apoptosis_Homo sapiens_hsa04210 | 1.02454243 |
| 33 | Thyroid cancer_Homo sapiens_hsa05216 | 1.01393939 |
| 34 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.99720124 |
| 35 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.99174704 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 0.94764520 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.94374555 |
| 38 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.92104156 |
| 39 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.91733400 |
| 40 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.90244610 |
| 41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.87079691 |
| 42 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.85585303 |
| 43 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.80833598 |
| 44 | Spliceosome_Homo sapiens_hsa03040 | 0.80433975 |
| 45 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.79185562 |
| 46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.75246819 |
| 47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.74440836 |
| 48 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.72714680 |
| 49 | Homologous recombination_Homo sapiens_hsa03440 | 0.72503829 |
| 50 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72166465 |
| 51 | HTLV-I infection_Homo sapiens_hsa05166 | 0.71922782 |
| 52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.71188632 |
| 53 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.69315865 |
| 54 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.68128896 |
| 55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.67892247 |
| 56 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.65395112 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.63519876 |
| 58 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.59919869 |
| 59 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.58896869 |
| 60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.58675305 |
| 61 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.58379544 |
| 62 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.57330959 |
| 63 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.56424537 |
| 64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.55432478 |
| 65 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.51313462 |
| 66 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.47697255 |
| 67 | Viral myocarditis_Homo sapiens_hsa05416 | 0.46145391 |
| 68 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.45741096 |
| 69 | Parkinsons disease_Homo sapiens_hsa05012 | 0.44590799 |
| 70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.44518599 |
| 71 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.43054009 |
| 72 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.42540389 |
| 73 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.39264720 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39147128 |
| 75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.36035094 |
| 76 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.35695338 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.31564746 |
| 78 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.30929808 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.28861091 |
| 80 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.28361033 |
| 81 | ABC transporters_Homo sapiens_hsa02010 | 0.27603091 |
| 82 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.27171281 |
| 83 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.26142656 |
| 84 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.23152513 |
| 85 | Olfactory transduction_Homo sapiens_hsa04740 | 0.23130498 |
| 86 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.20870692 |
| 87 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.19750820 |
| 88 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.19381052 |
| 89 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.18938724 |
| 90 | Hepatitis B_Homo sapiens_hsa05161 | 0.17904201 |
| 91 | RNA degradation_Homo sapiens_hsa03018 | 0.17892517 |
| 92 | Alzheimers disease_Homo sapiens_hsa05010 | 0.15983477 |
| 93 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.15965081 |
| 94 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.15613160 |
| 95 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.15456068 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.14658426 |
| 97 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.12984888 |
| 98 | Morphine addiction_Homo sapiens_hsa05032 | 0.12096644 |
| 99 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.12029503 |
| 100 | Platelet activation_Homo sapiens_hsa04611 | 0.10848955 |

