XPR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)5.32825244
2pyrimidine nucleobase catabolic process (GO:0006208)5.28146946
3locomotory exploration behavior (GO:0035641)5.10560508
4vocalization behavior (GO:0071625)5.02417513
5regulation of short-term neuronal synaptic plasticity (GO:0048172)5.02198391
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.96464203
7synaptic vesicle maturation (GO:0016188)4.95158771
8neuron cell-cell adhesion (GO:0007158)4.86883024
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.81218917
10dendritic spine morphogenesis (GO:0060997)4.77690886
11regulation of glutamate receptor signaling pathway (GO:1900449)4.59751304
12nucleobase catabolic process (GO:0046113)4.50538705
13dendrite morphogenesis (GO:0048813)4.46286534
14protein localization to synapse (GO:0035418)4.45609500
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.42570981
16neuron recognition (GO:0008038)4.33516975
17synaptic vesicle exocytosis (GO:0016079)4.18936495
18exploration behavior (GO:0035640)4.17839907
19cell migration in hindbrain (GO:0021535)4.09736128
20central nervous system projection neuron axonogenesis (GO:0021952)4.08843666
21axonal fasciculation (GO:0007413)4.06966295
22regulation of synapse structural plasticity (GO:0051823)4.04233006
23postsynaptic membrane organization (GO:0001941)4.03103921
24ionotropic glutamate receptor signaling pathway (GO:0035235)4.02658125
25proline transport (GO:0015824)3.88444463
26regulation of synaptic vesicle exocytosis (GO:2000300)3.85401476
27neurotransmitter-gated ion channel clustering (GO:0072578)3.80131921
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.70119307
29establishment of mitochondrion localization (GO:0051654)3.66060111
30glutamate receptor signaling pathway (GO:0007215)3.61195578
31glutamate secretion (GO:0014047)3.61086888
32negative regulation of dendrite development (GO:2000171)3.52620186
33neurotransmitter secretion (GO:0007269)3.50781282
34axon extension (GO:0048675)3.45924318
35regulation of long-term neuronal synaptic plasticity (GO:0048169)3.45427827
36regulation of synaptic vesicle transport (GO:1902803)3.40508684
37regulation of neuronal synaptic plasticity (GO:0048168)3.34563072
38mitochondrion transport along microtubule (GO:0047497)3.31764681
39establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.31764681
40presynaptic membrane assembly (GO:0097105)3.31546031
41synaptic vesicle docking involved in exocytosis (GO:0016081)3.30799738
42synaptic transmission, glutamatergic (GO:0035249)3.30024108
43regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.28574229
44gamma-aminobutyric acid transport (GO:0015812)3.28566160
45auditory behavior (GO:0031223)3.26617125
46clathrin coat assembly (GO:0048268)3.26178506
47central nervous system neuron axonogenesis (GO:0021955)3.25051427
48regulation of dendritic spine morphogenesis (GO:0061001)3.22477116
49limb bud formation (GO:0060174)3.20405936
50membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.18382407
51regulation of NFAT protein import into nucleus (GO:0051532)3.15006649
52cerebellar Purkinje cell differentiation (GO:0021702)3.13219867
53response to auditory stimulus (GO:0010996)3.09953849
54positive regulation of membrane potential (GO:0045838)3.09760780
55regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.09644915
56synapse assembly (GO:0007416)3.09107583
57activation of protein kinase A activity (GO:0034199)3.08766399
58long-term memory (GO:0007616)3.06339471
59positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.05801643
60regulation of excitatory postsynaptic membrane potential (GO:0060079)3.05137732
61positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.02601759
62neuron-neuron synaptic transmission (GO:0007270)3.01727181
63neuron projection extension (GO:1990138)3.01434410
64establishment of nucleus localization (GO:0040023)2.98661708
65retinal ganglion cell axon guidance (GO:0031290)2.97496733
66positive regulation of synapse maturation (GO:0090129)2.96982444
67innervation (GO:0060384)2.95448989
68positive regulation of synaptic transmission, GABAergic (GO:0032230)2.94992541
69regulation of postsynaptic membrane potential (GO:0060078)2.94961432
70neuromuscular process controlling balance (GO:0050885)2.94753246
71negative chemotaxis (GO:0050919)2.94618567
72regulation of axon guidance (GO:1902667)2.93173527
73negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.92602642
74positive regulation of dendritic spine morphogenesis (GO:0061003)2.91076265
75regulation of ARF protein signal transduction (GO:0032012)2.89750531
76transmission of nerve impulse (GO:0019226)2.89488435
77neurofilament cytoskeleton organization (GO:0060052)2.89360932
78positive regulation of action potential (GO:0045760)2.88931070
79cell communication by electrical coupling (GO:0010644)2.88863417
80sympathetic nervous system development (GO:0048485)2.88427278
81response to histamine (GO:0034776)2.88098247
82cerebellar granule cell differentiation (GO:0021707)2.88083426
83cytoplasmic mRNA processing body assembly (GO:0033962)2.87920688
84cerebral cortex radially oriented cell migration (GO:0021799)2.87504485
85calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.87484551
86regulation of dendritic spine development (GO:0060998)2.86051566
87positive regulation of dendritic spine development (GO:0060999)2.85765808
88apical protein localization (GO:0045176)2.85326274
89presynaptic membrane organization (GO:0097090)2.84338885
90cellular potassium ion homeostasis (GO:0030007)2.83044004
91prepulse inhibition (GO:0060134)2.82538410
92regulation of synaptic transmission, glutamatergic (GO:0051966)2.82439985
93neurotransmitter transport (GO:0006836)2.81867061
94dendritic spine organization (GO:0097061)2.81382352
95dopamine receptor signaling pathway (GO:0007212)2.80551008
96membrane assembly (GO:0071709)2.80135213
97cardiac chamber formation (GO:0003207)2.79867893
98synapse organization (GO:0050808)2.79852699
99hippocampus development (GO:0021766)2.79299225
100axon extension involved in axon guidance (GO:0048846)2.79250511
101neuron projection extension involved in neuron projection guidance (GO:1902284)2.79250511
102adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.78807805
103cerebral cortex cell migration (GO:0021795)2.78780925
104neuron migration (GO:0001764)2.78389375
105spinal cord development (GO:0021510)2.78192051
106regulation of cAMP-dependent protein kinase activity (GO:2000479)2.78062977
107regulation of neurotransmitter secretion (GO:0046928)2.76817155
108positive regulation of synapse assembly (GO:0051965)2.76096900
109epithelial cell differentiation involved in kidney development (GO:0035850)2.76063133
110positive regulation of axon extension (GO:0045773)2.75028105
111regulation of synapse assembly (GO:0051963)2.74168056
112axonogenesis (GO:0007409)2.73989258
113nerve growth factor signaling pathway (GO:0038180)2.73749444
114heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.73745557
115G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.71966752
116synaptic vesicle endocytosis (GO:0048488)2.71668685
117cardiac ventricle formation (GO:0003211)2.71061518
118sodium ion export (GO:0071436)2.69368163
119intraspecies interaction between organisms (GO:0051703)2.68963800
120social behavior (GO:0035176)2.68963800
121atrial cardiac muscle cell action potential (GO:0086014)2.68742112
122alanine transport (GO:0032328)2.68151496
123dendrite development (GO:0016358)2.67764573
124organelle transport along microtubule (GO:0072384)2.65247969
125membrane depolarization during action potential (GO:0086010)2.64405629
126regulation of synapse organization (GO:0050807)2.64222994
127cerebellum development (GO:0021549)2.64189967
128behavioral fear response (GO:0001662)2.63103148
129behavioral defense response (GO:0002209)2.63103148
130cell communication involved in cardiac conduction (GO:0086065)2.61130312
131negative regulation of axon extension (GO:0030517)2.60406949
132mechanosensory behavior (GO:0007638)2.59576920
133regulation of axon extension involved in axon guidance (GO:0048841)2.58796168
134homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.54133845
135cochlea development (GO:0090102)2.49731505
136cardiac right ventricle morphogenesis (GO:0003215)2.48527380
137negative regulation of cytosolic calcium ion concentration (GO:0051481)2.43534436
138ephrin receptor signaling pathway (GO:0048013)2.43137553
139gastrulation with mouth forming second (GO:0001702)2.41753187
140negative regulation of microtubule polymerization (GO:0031115)2.41405983
141neuronal ion channel clustering (GO:0045161)2.40438502
142negative regulation of axon guidance (GO:1902668)2.40177606
143neural tube formation (GO:0001841)2.39128446
144regulation of axon extension (GO:0030516)2.38011445
145regulation of collateral sprouting (GO:0048670)2.37712270
146retina layer formation (GO:0010842)2.36759781
147olfactory bulb development (GO:0021772)2.36618519
148neuron projection morphogenesis (GO:0048812)2.35920572

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.47081404
2GBX2_23144817_ChIP-Seq_PC3_Human3.29570766
3RBPJ_22232070_ChIP-Seq_NCS_Mouse2.85094158
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.73246369
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.62803262
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.55926735
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.52894891
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.38061928
9AR_21572438_ChIP-Seq_LNCaP_Human2.34734584
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.34093820
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.34093820
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.33077130
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.22835953
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.22129152
15REST_21632747_ChIP-Seq_MESCs_Mouse2.21464832
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.21154555
17DROSHA_22980978_ChIP-Seq_HELA_Human2.17240755
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12731213
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.12358487
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.12355254
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.03576671
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.01409504
23NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.98930245
24EED_16625203_ChIP-ChIP_MESCs_Mouse1.97716207
25SUZ12_27294783_Chip-Seq_ESCs_Mouse1.96010554
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.87420578
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76178823
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.74932680
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.74895837
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.73630367
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72890965
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70304493
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70231384
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.63894815
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.63240293
36* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.63030768
37* SMAD4_21799915_ChIP-Seq_A2780_Human1.58134781
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56151899
39ZNF274_21170338_ChIP-Seq_K562_Hela1.55769429
40EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50284986
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.48372175
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.47116009
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.45842148
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.45070547
45EWS_26573619_Chip-Seq_HEK293_Human1.43842091
46TAF15_26573619_Chip-Seq_HEK293_Human1.43207765
47* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42176257
48P300_19829295_ChIP-Seq_ESCs_Human1.40667188
49* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.40443295
50* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40425551
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.40369784
52* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36236887
53STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.34450832
54PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34039306
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.33400865
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.32563292
57* SOX2_21211035_ChIP-Seq_LN229_Gbm1.32389451
58RING1B_27294783_Chip-Seq_ESCs_Mouse1.31815497
59IGF1R_20145208_ChIP-Seq_DFB_Human1.31449167
60AR_25329375_ChIP-Seq_VCAP_Human1.31125160
61ARNT_22903824_ChIP-Seq_MCF-7_Human1.31015762
62* SMAD3_21741376_ChIP-Seq_EPCs_Human1.29303970
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.28938598
64* SOX9_26525672_Chip-Seq_HEART_Mouse1.28616765
65AHR_22903824_ChIP-Seq_MCF-7_Human1.27993952
66IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27270739
67WT1_19549856_ChIP-ChIP_CCG9911_Human1.27218162
68RNF2_27304074_Chip-Seq_NSC_Mouse1.26804255
69KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.25661167
70LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25547635
71TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25225030
72* NANOG_18555785_Chip-Seq_ESCs_Mouse1.23397199
73* RING1B_27294783_Chip-Seq_NPCs_Mouse1.21955670
74MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.21751247
75STAT3_23295773_ChIP-Seq_U87_Human1.21517846
76POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21159368
77TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21159368
78AR_19668381_ChIP-Seq_PC3_Human1.20859544
79* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20615181
80TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.19326831
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.19191147
82* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18955177
83HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.18336050
84CBP_20019798_ChIP-Seq_JUKART_Human1.16561191
85IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16561191
86CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16086219
87EP300_21415370_ChIP-Seq_HL-1_Mouse1.15351107
88WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15196312
89* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.13785366
90POU5F1_16153702_ChIP-ChIP_HESCs_Human1.13717689
91* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13713525
92TP53_16413492_ChIP-PET_HCT116_Human1.13342260
93ISL1_27105846_Chip-Seq_CPCs_Mouse1.12738850
94* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12735943
95YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11545204
96VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.11544040
97BMI1_23680149_ChIP-Seq_NPCS_Mouse1.10392060
98TCF4_23295773_ChIP-Seq_U87_Human1.09345904
99* JUN_21703547_ChIP-Seq_K562_Human1.09330488
100CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08681720
101* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08348972
102* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.07416933
103KDM2B_26808549_Chip-Seq_K562_Human1.04759596
104SMAD4_21741376_ChIP-Seq_HESCs_Human1.04692250
105TBX3_20139965_ChIP-Seq_MESCs_Mouse1.04676072
106* RUNX2_22187159_ChIP-Seq_PCA_Human1.03760347
107MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02656873
108* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00667026
109ER_23166858_ChIP-Seq_MCF-7_Human1.00418990
110BCAT_22108803_ChIP-Seq_LS180_Human0.99185860
111* PRDM14_20953172_ChIP-Seq_ESCs_Human0.98104937
112ERG_21242973_ChIP-ChIP_JURKAT_Human0.97602155
113TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97582026
114* TP53_18474530_ChIP-ChIP_U2OS_Human0.97111881
115FUS_26573619_Chip-Seq_HEK293_Human0.95662394
116* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.95228552
117* SMAD3_21741376_ChIP-Seq_ESCs_Human0.94275281
118UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93692658
119RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93526283
120TCF4_18268006_ChIP-ChIP_LS174T_Human0.90789424
121RXR_22108803_ChIP-Seq_LS180_Human0.88942552
122SMAD3_21741376_ChIP-Seq_HESCs_Human0.88819214

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.67040065
2MP0003880_abnormal_central_pattern4.21307387
3MP0003635_abnormal_synaptic_transmissio3.70918432
4MP0004270_analgesia3.63599473
5MP0005423_abnormal_somatic_nervous3.28300252
6MP0002063_abnormal_learning/memory/cond3.16776835
7MP0000569_abnormal_digit_pigmentation2.98813020
8MP0000778_abnormal_nervous_system2.86286237
9MP0009745_abnormal_behavioral_response2.82436335
10MP0002734_abnormal_mechanical_nocicepti2.58048962
11MP0002572_abnormal_emotion/affect_behav2.54557429
12MP0002064_seizures2.51373064
13MP0001968_abnormal_touch/_nociception2.50393638
14MP0009046_muscle_twitch2.46449137
15MP0001486_abnormal_startle_reflex2.37362034
16MP0009780_abnormal_chondrocyte_physiolo2.28695106
17MP0006276_abnormal_autonomic_nervous2.13932011
18MP0001440_abnormal_grooming_behavior2.04843171
19MP0005645_abnormal_hypothalamus_physiol2.04625785
20MP0003121_genomic_imprinting2.04308685
21MP0002557_abnormal_social/conspecific_i2.03790462
22MP0003890_abnormal_embryonic-extraembry2.01636112
23MP0002184_abnormal_innervation2.01263992
24MP0001984_abnormal_olfaction1.95573036
25MP0002735_abnormal_chemical_nociception1.94691364
26MP0004811_abnormal_neuron_physiology1.87746474
27MP0002733_abnormal_thermal_nociception1.87140485
28MP0004858_abnormal_nervous_system1.81731460
29MP0005646_abnormal_pituitary_gland1.80497320
30MP0002067_abnormal_sensory_capabilities1.78871130
31MP0004924_abnormal_behavior1.74990441
32MP0005386_behavior/neurological_phenoty1.74990441
33MP0004885_abnormal_endolymph1.73960116
34MP0002909_abnormal_adrenal_gland1.72434965
35MP0002822_catalepsy1.69945123
36MP0002272_abnormal_nervous_system1.68356008
37MP0001970_abnormal_pain_threshold1.65819827
38MP0001501_abnormal_sleep_pattern1.57348318
39MP0000955_abnormal_spinal_cord1.55790308
40MP0001502_abnormal_circadian_rhythm1.53734234
41MP0002736_abnormal_nociception_after1.53575475
42MP0002882_abnormal_neuron_morphology1.50375687
43MP0008569_lethality_at_weaning1.48286575
44MP0002751_abnormal_autonomic_nervous1.44179852
45MP0000534_abnormal_ureter_morphology1.41368859
46MP0000566_synostosis1.41261382
47MP0005409_darkened_coat_color1.39000124
48MP0003937_abnormal_limbs/digits/tail_de1.35375289
49MP0002152_abnormal_brain_morphology1.34500565
50MP0003122_maternal_imprinting1.33187532
51MP0003787_abnormal_imprinting1.31216876
52MP0003119_abnormal_digestive_system1.28495216
53MP0002066_abnormal_motor_capabilities/c1.28470324
54MP0000631_abnormal_neuroendocrine_gland1.27478793
55MP0000537_abnormal_urethra_morphology1.24990737
56MP0003942_abnormal_urinary_system1.23618883
57MP0001188_hyperpigmentation1.22446037
58MP0003879_abnormal_hair_cell1.20372551
59MP0002638_abnormal_pupillary_reflex1.16703964
60MP0003385_abnormal_body_wall1.15787213
61MP0005499_abnormal_olfactory_system1.11973897
62MP0005394_taste/olfaction_phenotype1.11973897
63MP0008961_abnormal_basal_metabolism1.11529251
64MP0005187_abnormal_penis_morphology1.09397554
65MP0002102_abnormal_ear_morphology1.08453191
66MP0003329_amyloid_beta_deposits1.07133559
67MP0003633_abnormal_nervous_system1.06839520
68MP0002233_abnormal_nose_morphology1.03413380
69MP0005551_abnormal_eye_electrophysiolog1.03343883
70MP0000579_abnormal_nail_morphology1.02616793
71MP0003935_abnormal_craniofacial_develop1.02388938
72MP0000751_myopathy1.02139893
73MP0001299_abnormal_eye_distance/1.01882780
74MP0003755_abnormal_palate_morphology1.01639154
75MP0004133_heterotaxia0.97401352
76MP0004742_abnormal_vestibular_system0.95638155
77MP0005248_abnormal_Harderian_gland0.95461305
78MP0002069_abnormal_eating/drinking_beha0.95224953
79MP0003567_abnormal_fetal_cardiomyocyte0.95074780
80MP0003861_abnormal_nervous_system0.92366655
81MP0002697_abnormal_eye_size0.92018485
82MP0008877_abnormal_DNA_methylation0.91806901
83MP0000516_abnormal_urinary_system0.91600651
84MP0005367_renal/urinary_system_phenotyp0.91600651
85MP0003690_abnormal_glial_cell0.89599463
86MP0008789_abnormal_olfactory_epithelium0.88445970
87MP0003631_nervous_system_phenotype0.88418023
88MP0004130_abnormal_muscle_cell0.87877568
89MP0003634_abnormal_glial_cell0.87533341
90MP0004085_abnormal_heartbeat0.87422464
91MP0001286_abnormal_eye_development0.86522213
92MP0002752_abnormal_somatic_nervous0.86409245
93MP0005623_abnormal_meninges_morphology0.84588651
94MP0000049_abnormal_middle_ear0.84149741
95MP0004084_abnormal_cardiac_muscle0.83956852
96MP0001177_atelectasis0.83090525
97MP0002090_abnormal_vision0.81650116
98MP0003137_abnormal_impulse_conducting0.80486965
99MP0003221_abnormal_cardiomyocyte_apopto0.80236608
100MP0004145_abnormal_muscle_electrophysio0.80043893
101MP0002089_abnormal_postnatal_growth/wei0.79127655
102MP0005253_abnormal_eye_physiology0.78212684
103MP0001529_abnormal_vocalization0.78202788
104MP0002229_neurodegeneration0.76965213
105MP0000462_abnormal_digestive_system0.76720083
106MP0009703_decreased_birth_body0.75992582
107MP0005167_abnormal_blood-brain_barrier0.75104191
108MP0000647_abnormal_sebaceous_gland0.74905787
109MP0001293_anophthalmia0.72964999
110MP0004142_abnormal_muscle_tone0.71791628
111MP0003123_paternal_imprinting0.71293402
112MP0001963_abnormal_hearing_physiology0.71186489
113MP0006072_abnormal_retinal_apoptosis0.70707516
114MP0001905_abnormal_dopamine_level0.69595588
115MP0004215_abnormal_myocardial_fiber0.68938713
116MP0004233_abnormal_muscle_weight0.67969879
117MP0004484_altered_response_of0.67929101
118MP0002081_perinatal_lethality0.62978455
119MP0001943_abnormal_respiration0.62505760
120MP0010386_abnormal_urinary_bladder0.62231070
121MP0002082_postnatal_lethality0.62087586
122MP0010770_preweaning_lethality0.62087586
123MP0003632_abnormal_nervous_system0.61350693
124MP0010769_abnormal_survival0.61041151
125MP0002234_abnormal_pharynx_morphology0.60972575
126MP0000015_abnormal_ear_pigmentation0.60405006
127MP0005535_abnormal_body_temperature0.58747031
128MP0003303_peritoneal_inflammation0.58089760
129MP0005195_abnormal_posterior_eye0.57326279
130MP0008874_decreased_physiological_sensi0.56564114
131MP0010768_mortality/aging0.56183587

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.54409305
2Focal seizures (HP:0007359)4.41163818
3Mutism (HP:0002300)4.17662021
4Myokymia (HP:0002411)4.09263044
5Progressive cerebellar ataxia (HP:0002073)3.76665608
6Supranuclear gaze palsy (HP:0000605)3.60852094
7Genetic anticipation (HP:0003743)3.53727208
8Broad-based gait (HP:0002136)3.53331270
9Epileptic encephalopathy (HP:0200134)3.52506305
10Drooling (HP:0002307)3.49597097
11Excessive salivation (HP:0003781)3.49597097
12Visual hallucinations (HP:0002367)3.40176866
13Cortical dysplasia (HP:0002539)3.35236510
14Polyphagia (HP:0002591)3.28754144
15Febrile seizures (HP:0002373)3.25990753
16Papilledema (HP:0001085)3.14471593
17Ankle clonus (HP:0011448)3.08407938
18Inappropriate behavior (HP:0000719)3.01504094
19Amyotrophic lateral sclerosis (HP:0007354)2.96094929
20Urinary bladder sphincter dysfunction (HP:0002839)2.94475749
21Abnormality of the corticospinal tract (HP:0002492)2.84665486
22Abnormal eating behavior (HP:0100738)2.82607469
23Agitation (HP:0000713)2.79123354
24Action tremor (HP:0002345)2.71001226
25Generalized tonic-clonic seizures (HP:0002069)2.70844309
26Absence seizures (HP:0002121)2.65548809
27Progressive inability to walk (HP:0002505)2.65204581
28Impaired vibration sensation in the lower limbs (HP:0002166)2.65086281
29Macroorchidism (HP:0000053)2.64605972
30Urinary urgency (HP:0000012)2.64296594
31Elfin facies (HP:0004428)2.62007170
32Truncal ataxia (HP:0002078)2.60598430
33Poor eye contact (HP:0000817)2.57330265
34Diplopia (HP:0000651)2.54861545
35Abnormality of binocular vision (HP:0011514)2.54861545
36Hyperventilation (HP:0002883)2.54727611
37Atonic seizures (HP:0010819)2.52395760
38Abnormal social behavior (HP:0012433)2.49577852
39Impaired social interactions (HP:0000735)2.49577852
40Hemiparesis (HP:0001269)2.49544854
41Hepatoblastoma (HP:0002884)2.47427992
42Stereotypic behavior (HP:0000733)2.44872768
43Limb dystonia (HP:0002451)2.44256427
44Vitreoretinal degeneration (HP:0000655)2.39918459
45Dialeptic seizures (HP:0011146)2.35749011
46Obstructive sleep apnea (HP:0002870)2.34061883
47Astrocytoma (HP:0009592)2.33820576
48Abnormality of the astrocytes (HP:0100707)2.33820576
49Pheochromocytoma (HP:0002666)2.32795290
50Hyperacusis (HP:0010780)2.32507311
51Insidious onset (HP:0003587)2.31666367
52Termporal pattern (HP:0011008)2.31666367
53Thyroid carcinoma (HP:0002890)2.30377661
54Exotropia (HP:0000577)2.29835628
55Amblyopia (HP:0000646)2.29695463
56Fetal akinesia sequence (HP:0001989)2.29309833
57Insomnia (HP:0100785)2.27652482
58Cutaneous finger syndactyly (HP:0010554)2.26557827
59Megalencephaly (HP:0001355)2.24951623
60Abnormality of salivation (HP:0100755)2.24926568
61Open mouth (HP:0000194)2.23718738
62Aqueductal stenosis (HP:0002410)2.18802982
63Pachygyria (HP:0001302)2.18423895
64Postural instability (HP:0002172)2.17578479
65Apathy (HP:0000741)2.16983874
66Depression (HP:0000716)2.15502047
67Inability to walk (HP:0002540)2.13853434
68Akinesia (HP:0002304)2.12646475
69Overriding aorta (HP:0002623)2.11837820
70Abnormality of the labia minora (HP:0012880)2.11129793
71Disinhibition (HP:0000734)2.10929707
72Short 4th metacarpal (HP:0010044)2.09996487
73Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.09996487
74Volvulus (HP:0002580)2.06495404
75Neurofibrillary tangles (HP:0002185)2.05364600
76Gaze-evoked nystagmus (HP:0000640)2.04612579
77Protruding tongue (HP:0010808)2.03512570
78EEG with generalized epileptiform discharges (HP:0011198)2.02392790
79Epileptiform EEG discharges (HP:0011182)2.02135680
80Torticollis (HP:0000473)2.00708149
81Aplasia/Hypoplasia of the brainstem (HP:0007362)2.00306278
82Hypoplasia of the brainstem (HP:0002365)2.00306278
83Anxiety (HP:0000739)2.00009750
84Sleep apnea (HP:0010535)1.99450437
85Renovascular hypertension (HP:0100817)1.98399715
86Medulloblastoma (HP:0002885)1.97181027
87Hypsarrhythmia (HP:0002521)1.96999892
88Absent speech (HP:0001344)1.96836620
89Gait imbalance (HP:0002141)1.96546969
90Dysdiadochokinesis (HP:0002075)1.95786407
91Lower limb muscle weakness (HP:0007340)1.95561388
92Midline defect of the nose (HP:0004122)1.95047973
93Papillary thyroid carcinoma (HP:0002895)1.94611415
94Morphological abnormality of the pyramidal tract (HP:0002062)1.93879374
95Sacral dimple (HP:0000960)1.93228949
96Cutaneous syndactyly (HP:0012725)1.92749330
97Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.90858929
98Degeneration of the lateral corticospinal tracts (HP:0002314)1.90858929
99Ulnar claw (HP:0001178)1.89798638
100Spastic gait (HP:0002064)1.89768025
101Lissencephaly (HP:0001339)1.88190610
102Diminished motivation (HP:0000745)1.88028429
103Enlarged penis (HP:0000040)1.87782730
104Blue irides (HP:0000635)1.87000893
105Pointed chin (HP:0000307)1.86554104
106Cerebral inclusion bodies (HP:0100314)1.86552201
107Labial hypoplasia (HP:0000066)1.86399926
108Neoplasm of the adrenal cortex (HP:0100641)1.84758371
109Autism (HP:0000717)1.84593239
110Sporadic (HP:0003745)1.83490796
111Shawl scrotum (HP:0000049)1.82028088
112Lower limb amyotrophy (HP:0007210)1.81297765
113Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.80821238
114Heterotopia (HP:0002282)1.80497979
115Impaired smooth pursuit (HP:0007772)1.79231790
116Obsessive-compulsive behavior (HP:0000722)1.79097402
117Narrow forehead (HP:0000341)1.77623840
118Renal hypoplasia (HP:0000089)1.77596399
119Spastic tetraplegia (HP:0002510)1.77526759
120Genital tract atresia (HP:0001827)1.77117354
121Curly hair (HP:0002212)1.76917585
122Generalized hypopigmentation of hair (HP:0011358)1.76784022
123Widely spaced teeth (HP:0000687)1.76782538
124Gastroesophageal reflux (HP:0002020)1.76155167
125Flat cornea (HP:0007720)1.75941518
126Abnormality of the lower motor neuron (HP:0002366)1.75069260
127Lower limb asymmetry (HP:0100559)1.74224306
128Glioma (HP:0009733)1.74178596
129Aplasia/Hypoplasia of the sternum (HP:0006714)1.73543124
130Neuroendocrine neoplasm (HP:0100634)1.73074883
131Absent eyebrow (HP:0002223)1.71376979
132Retinal dysplasia (HP:0007973)1.70366602
133Hypoplasia of the corpus callosum (HP:0002079)1.70211293
134Hypothermia (HP:0002045)1.67169962
135High anterior hairline (HP:0009890)1.65413870
136Syncope (HP:0001279)1.65083810
137Polymicrogyria (HP:0002126)1.62666545
138Optic nerve hypoplasia (HP:0000609)1.62178288
139Vaginal atresia (HP:0000148)1.60719124
140Hypoplastic female external genitalia (HP:0012815)1.60174694
141Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.58434548
142Abnormality of the pubic bones (HP:0003172)1.58171629
143Micropenis (HP:0000054)1.57533999
144Fair hair (HP:0002286)1.57512078
145Neoplasm of the oral cavity (HP:0100649)1.57429075

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK16.72625149
2MAP3K93.25827375
3NTRK33.20051614
4BCR2.90253267
5NTRK22.72046672
6MAP3K42.59507540
7MAPK132.44147026
8MAP2K72.31685620
9EPHA42.24847695
10PHKG12.21652518
11PHKG22.21652518
12TNIK2.20622740
13SIK22.11119658
14MINK12.04806441
15PAK61.91529497
16CASK1.85953968
17ERBB31.73428134
18KSR11.64073745
19DYRK21.63039030
20CAMK1G1.47422266
21PRKD31.40139241
22MAP2K41.36139821
23DAPK21.35862432
24CSNK1G21.35573028
25CDK51.33239659
26CAMKK11.32509982
27EPHA31.31397600
28WNK31.17547583
29LATS11.11586792
30SGK21.08931873
31UHMK11.06715770
32FGFR21.06590642
33EPHB21.06017739
34TRIM281.03234366
35LATS21.02833641
36RET1.02782685
37DYRK1A1.02394117
38PNCK1.01046877
39PAK31.00269128
40MAP3K101.00154468
41MARK20.98002203
42MKNK20.95227768
43MAP3K60.93052108
44SGK30.92869764
45PRKCG0.91968192
46FES0.90528116
47TYRO30.90359510
48SGK2230.88632865
49SGK4940.88632865
50STK110.88544226
51KSR20.87880224
52BRD40.87312822
53MAP3K20.83567496
54CAMK1D0.83400198
55CSNK1A1L0.82546732
56TAOK10.81997079
57SRPK10.79844791
58PLK20.79443772
59DYRK30.78685099
60SGK10.74768555
61CSNK1G30.72477986
62NTRK10.71963220
63PRKCZ0.71865274
64YES10.71752763
65SCYL20.68705594
66MAPK120.68309096
67CAMK2A0.67890047
68LMTK20.67186951
69RPS6KA20.66985117
70CAMK10.66233093
71MAP3K120.65877934
72STK380.64828970
73DMPK0.64198691
74TSSK60.64109134
75PRKCH0.62834775
76CAMKK20.61827975
77PKN10.61725390
78CDK180.60972760
79CSNK1G10.60640285
80CDK150.59507998
81STK38L0.58770763
82CDK140.57836019
83ALK0.57252744
84MKNK10.55955664
85FRK0.55261829
86GRK50.55159192
87RIPK10.54982695
88INSRR0.54360512
89CAMK2B0.54268490
90PRKCE0.52651985
91MAP4K20.52535555
92PRKAA10.51866019
93FYN0.49709418
94CDK11A0.48845430
95FGFR30.48186295
96CAMK40.47731546
97CSNK1E0.47307379
98ERBB20.45842861
99CSNK1D0.44744826
100RPS6KA30.44471867
101MET0.43443440
102CDC42BPA0.42778919
103PINK10.42578090
104ROCK10.42161770
105MAPK90.42109161
106AKT30.42103296
107TRIB30.41939003
108FER0.41760864
109MAPK100.41556012
110MAPK40.38817595
111MAPK80.37612866
112DAPK10.37179332
113RPS6KB10.36694521
114PRKCB0.36260232
115PRKG10.36026749
116PKN20.35785418
117MUSK0.35712613
118MAP2K60.35357029
119DYRK1B0.35300218
120PDGFRA0.34043529
121PRPF4B0.33854056
122CCNB10.33600662
123PRKACB0.32582016
124GSK3B0.32469296
125CDK30.32176131
126ROCK20.31282444
127OBSCN0.29346467
128ATM0.29327244
129MAP3K50.28140759
130CLK10.27260610

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.15919311
2Circadian entrainment_Homo sapiens_hsa047132.31775601
3GABAergic synapse_Homo sapiens_hsa047272.29372633
4Olfactory transduction_Homo sapiens_hsa047402.27954059
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.20152226
6Glutamatergic synapse_Homo sapiens_hsa047242.20022411
7Synaptic vesicle cycle_Homo sapiens_hsa047212.19751708
8Morphine addiction_Homo sapiens_hsa050322.12705894
9Long-term potentiation_Homo sapiens_hsa047202.00347218
10Dopaminergic synapse_Homo sapiens_hsa047281.86547440
11Steroid biosynthesis_Homo sapiens_hsa001001.84888121
12Cholinergic synapse_Homo sapiens_hsa047251.79580406
13Axon guidance_Homo sapiens_hsa043601.77319359
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.77106698
15Amphetamine addiction_Homo sapiens_hsa050311.76622755
16Salivary secretion_Homo sapiens_hsa049701.65900672
17Insulin secretion_Homo sapiens_hsa049111.59389380
18Cocaine addiction_Homo sapiens_hsa050301.56616629
19Gastric acid secretion_Homo sapiens_hsa049711.55403469
20Renin secretion_Homo sapiens_hsa049241.55122311
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.54610000
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49678612
23Oxytocin signaling pathway_Homo sapiens_hsa049211.48064431
24Serotonergic synapse_Homo sapiens_hsa047261.42753475
25Long-term depression_Homo sapiens_hsa047301.39680979
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.37520386
27Type II diabetes mellitus_Homo sapiens_hsa049301.35802876
28Taste transduction_Homo sapiens_hsa047421.35648041
29Hippo signaling pathway_Homo sapiens_hsa043901.34883272
30Gap junction_Homo sapiens_hsa045401.34767523
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.34508646
32Hedgehog signaling pathway_Homo sapiens_hsa043401.32024632
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29848361
34GnRH signaling pathway_Homo sapiens_hsa049121.27645442
35Glioma_Homo sapiens_hsa052141.27365146
36ErbB signaling pathway_Homo sapiens_hsa040121.23464765
37Estrogen signaling pathway_Homo sapiens_hsa049151.22242058
38Calcium signaling pathway_Homo sapiens_hsa040201.21221892
39Endometrial cancer_Homo sapiens_hsa052131.19693862
40cAMP signaling pathway_Homo sapiens_hsa040241.16887681
41Adherens junction_Homo sapiens_hsa045201.15207252
42Phototransduction_Homo sapiens_hsa047441.14000942
43Dorso-ventral axis formation_Homo sapiens_hsa043201.12223180
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.10549537
45Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.08756377
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.08071301
47Basal cell carcinoma_Homo sapiens_hsa052171.07419378
48Colorectal cancer_Homo sapiens_hsa052101.02866248
49cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01670291
50Melanogenesis_Homo sapiens_hsa049161.01641836
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.98698239
52Carbohydrate digestion and absorption_Homo sapiens_hsa049730.96294629
53Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95911972
54Renal cell carcinoma_Homo sapiens_hsa052110.94691719
55Dilated cardiomyopathy_Homo sapiens_hsa054140.94680540
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.93071055
57Tight junction_Homo sapiens_hsa045300.92445362
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92032910
59Neurotrophin signaling pathway_Homo sapiens_hsa047220.92025074
60Choline metabolism in cancer_Homo sapiens_hsa052310.91859553
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.90102377
62Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.88899652
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.88891254
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88239547
65Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.85952957
66mTOR signaling pathway_Homo sapiens_hsa041500.85831994
67MAPK signaling pathway_Homo sapiens_hsa040100.85165171
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84999687
69Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.83020026
70Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.82800131
71Nitrogen metabolism_Homo sapiens_hsa009100.82166475
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.81891073
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.78391739
74Circadian rhythm_Homo sapiens_hsa047100.78177162
75Insulin signaling pathway_Homo sapiens_hsa049100.73604935
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73013007
77Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.72880075
78Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71970264
79Non-small cell lung cancer_Homo sapiens_hsa052230.71926280
80TGF-beta signaling pathway_Homo sapiens_hsa043500.70700627
81Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.70595964
82VEGF signaling pathway_Homo sapiens_hsa043700.68947787
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.68809300
84Butanoate metabolism_Homo sapiens_hsa006500.68269538
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67919599
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.67649786
87Melanoma_Homo sapiens_hsa052180.67476047
88Wnt signaling pathway_Homo sapiens_hsa043100.66935534
89Ras signaling pathway_Homo sapiens_hsa040140.66189372
90Glucagon signaling pathway_Homo sapiens_hsa049220.65976788
91AMPK signaling pathway_Homo sapiens_hsa041520.64988168
92Rap1 signaling pathway_Homo sapiens_hsa040150.64940597
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.64560850
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.62110148
95mRNA surveillance pathway_Homo sapiens_hsa030150.58754780
96Protein export_Homo sapiens_hsa030600.56847469
97Thyroid hormone synthesis_Homo sapiens_hsa049180.56229269
98Oocyte meiosis_Homo sapiens_hsa041140.56223606
99Prolactin signaling pathway_Homo sapiens_hsa049170.55523230
100Vibrio cholerae infection_Homo sapiens_hsa051100.54648670
101Pancreatic cancer_Homo sapiens_hsa052120.52257486
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51429172
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50963055
104Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50942073
105Ovarian steroidogenesis_Homo sapiens_hsa049130.50928493
106Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.50489904
107Viral myocarditis_Homo sapiens_hsa054160.50389768
108Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50313651
109MicroRNAs in cancer_Homo sapiens_hsa052060.49917305
110Bile secretion_Homo sapiens_hsa049760.49669724
111FoxO signaling pathway_Homo sapiens_hsa040680.49284426
112Cardiac muscle contraction_Homo sapiens_hsa042600.49013397
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48951605
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.48893395
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48595123
116Chronic myeloid leukemia_Homo sapiens_hsa052200.48569338
117Chemokine signaling pathway_Homo sapiens_hsa040620.48149433
118Platelet activation_Homo sapiens_hsa046110.48016870
119Collecting duct acid secretion_Homo sapiens_hsa049660.47496212
120Pancreatic secretion_Homo sapiens_hsa049720.46150834
121Focal adhesion_Homo sapiens_hsa045100.45078666
122Insulin resistance_Homo sapiens_hsa049310.44985888
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.44565707
124Alcoholism_Homo sapiens_hsa050340.44440128
125Endocytosis_Homo sapiens_hsa041440.44147862
126ECM-receptor interaction_Homo sapiens_hsa045120.43406004
127Inositol phosphate metabolism_Homo sapiens_hsa005620.43140969
128Maturity onset diabetes of the young_Homo sapiens_hsa049500.42391755
129Central carbon metabolism in cancer_Homo sapiens_hsa052300.41749764

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