XRCC5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)5.09611832
2folic acid-containing compound biosynthetic process (GO:0009396)4.99433979
3nuclear pore complex assembly (GO:0051292)4.83128172
4DNA unwinding involved in DNA replication (GO:0006268)4.75252227
5* establishment of integrated proviral latency (GO:0075713)4.63639765
6DNA replication-dependent nucleosome assembly (GO:0006335)4.55278080
7DNA replication-dependent nucleosome organization (GO:0034723)4.55278080
8DNA replication initiation (GO:0006270)4.40643597
9IMP biosynthetic process (GO:0006188)4.37207849
10nucleobase biosynthetic process (GO:0046112)4.35345590
11protein localization to kinetochore (GO:0034501)4.28245112
12regulation of gene silencing by miRNA (GO:0060964)4.27433842
13regulation of gene silencing by RNA (GO:0060966)4.27433842
14regulation of posttranscriptional gene silencing (GO:0060147)4.27433842
15formation of translation preinitiation complex (GO:0001731)4.17957557
16mitotic nuclear envelope disassembly (GO:0007077)4.17246023
17DNA ligation (GO:0006266)4.13931412
18DNA strand elongation involved in DNA replication (GO:0006271)4.12061176
19regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.10235509
20regulation of helicase activity (GO:0051095)4.03433780
21somatic hypermutation of immunoglobulin genes (GO:0016446)4.01511967
22somatic diversification of immune receptors via somatic mutation (GO:0002566)4.01511967
23mitotic metaphase plate congression (GO:0007080)3.99040707
24DNA strand elongation (GO:0022616)3.90264230
25nuclear envelope disassembly (GO:0051081)3.88937447
26membrane disassembly (GO:0030397)3.88937447
27purine nucleobase biosynthetic process (GO:0009113)3.88182936
28IMP metabolic process (GO:0046040)3.81616221
29ribosome assembly (GO:0042255)3.78429491
30maturation of SSU-rRNA (GO:0030490)3.72719321
31DNA topological change (GO:0006265)3.67408025
32telomere maintenance via semi-conservative replication (GO:0032201)3.64918577
33metaphase plate congression (GO:0051310)3.64648074
34* DNA duplex unwinding (GO:0032508)3.55888126
35regulation of translational fidelity (GO:0006450)3.55674900
36* DNA geometric change (GO:0032392)3.55246182
37DNA replication checkpoint (GO:0000076)3.54095433
38pore complex assembly (GO:0046931)3.52705830
39* non-recombinational repair (GO:0000726)3.52001634
40* double-strand break repair via nonhomologous end joining (GO:0006303)3.52001634
41ATP-dependent chromatin remodeling (GO:0043044)3.51059005
42regulation of mitotic sister chromatid separation (GO:0010965)3.44991652
43regulation of mitotic sister chromatid segregation (GO:0033047)3.44991652
44regulation of sister chromatid segregation (GO:0033045)3.44991652
45ribosome biogenesis (GO:0042254)3.44780157
46protein localization to chromosome, centromeric region (GO:0071459)3.43936168
47protein complex localization (GO:0031503)3.41810322
48DNA double-strand break processing (GO:0000729)3.38949761
49chromatin remodeling at centromere (GO:0031055)3.38120596
50ribosomal small subunit assembly (GO:0000028)3.32799719
51* establishment of viral latency (GO:0019043)3.31025517
52mitotic recombination (GO:0006312)3.27763130
53tetrahydrofolate metabolic process (GO:0046653)3.27374783
54mitotic sister chromatid segregation (GO:0000070)3.25394758
55regulation of sister chromatid cohesion (GO:0007063)3.24423318
56telomere maintenance via recombination (GO:0000722)3.24226325
57heterochromatin organization (GO:0070828)3.23772288
58regulation of histone H3-K9 methylation (GO:0051570)3.23634658
59pre-miRNA processing (GO:0031054)3.23634590
60regulation of spindle organization (GO:0090224)3.23304120
61regulation of centrosome cycle (GO:0046605)3.22431249
62ribosomal large subunit biogenesis (GO:0042273)3.21347871
63ribonucleoprotein complex biogenesis (GO:0022613)3.20634517
64telomere maintenance via telomere lengthening (GO:0010833)3.20228246
65CENP-A containing nucleosome assembly (GO:0034080)3.19712733
66DNA replication-independent nucleosome organization (GO:0034724)3.19169711
67DNA replication-independent nucleosome assembly (GO:0006336)3.19169711
68L-serine metabolic process (GO:0006563)3.17703244
69pteridine-containing compound biosynthetic process (GO:0042559)3.17600081
70negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.17572877
71mitotic chromosome condensation (GO:0007076)3.17253679
72regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.17180562
73paraxial mesoderm development (GO:0048339)3.17043394
74sister chromatid segregation (GO:0000819)3.15320185
75kinetochore organization (GO:0051383)3.15006488
76negative regulation of DNA-dependent DNA replication (GO:2000104)3.14080812
77regulation of mitotic spindle checkpoint (GO:1903504)3.13733808
78regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.13733808
79negative regulation of histone methylation (GO:0031061)3.12275270
80folic acid metabolic process (GO:0046655)3.10795590
81anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.10529127
82establishment of chromosome localization (GO:0051303)3.09687811
83DNA damage response, detection of DNA damage (GO:0042769)3.08352864
84nucleotide-excision repair, DNA gap filling (GO:0006297)3.05650152
85negative regulation of chromosome segregation (GO:0051985)3.05547789
86chaperone-mediated protein complex assembly (GO:0051131)3.03871484
87translational termination (GO:0006415)3.03581807
88DNA strand renaturation (GO:0000733)3.03358909
89negative regulation of DNA recombination (GO:0045910)3.03011290
90regulation of centriole replication (GO:0046599)3.02232879
91regulation of mitotic spindle organization (GO:0060236)3.02073388
92attachment of spindle microtubules to kinetochore (GO:0008608)3.01859014
93positive regulation of chromosome segregation (GO:0051984)3.01826296
94viral transcription (GO:0019083)2.99917197
95negative regulation of mitotic sister chromatid separation (GO:2000816)2.99859772
96negative regulation of mitotic sister chromatid segregation (GO:0033048)2.99859772
97negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.99859772
98negative regulation of sister chromatid segregation (GO:0033046)2.99859772
99chromosome segregation (GO:0007059)2.98787044
100translational initiation (GO:0006413)2.97395784
101mitotic G2/M transition checkpoint (GO:0044818)2.97271963
102negative regulation of mitosis (GO:0045839)2.96774061
103tRNA aminoacylation for protein translation (GO:0006418)2.96452563
104regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.96049678
105negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.94055522
106negative regulation of ligase activity (GO:0051352)2.94055522
107protein K6-linked ubiquitination (GO:0085020)2.93493720
108regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.92405219
109translational elongation (GO:0006414)2.91040427
110spindle assembly checkpoint (GO:0071173)2.90943979
111cellular protein complex localization (GO:0034629)2.90885987
112regulation of DNA endoreduplication (GO:0032875)2.90668595
113negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.90572613
114negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.90161986
115mitotic spindle assembly checkpoint (GO:0007094)2.89983776
116determination of adult lifespan (GO:0008340)2.89773529
117chromatin assembly or disassembly (GO:0006333)2.89628709
118nuclear envelope organization (GO:0006998)2.89407682
119regulation of mitotic metaphase/anaphase transition (GO:0030071)2.89002196
120regulation of chromosome segregation (GO:0051983)2.88450702
121histone exchange (GO:0043486)2.87065188
122postreplication repair (GO:0006301)2.86990969
123rRNA processing (GO:0006364)2.86272711
124amino acid activation (GO:0043038)2.86111174
125tRNA aminoacylation (GO:0043039)2.86111174
126mitotic spindle checkpoint (GO:0071174)2.85424517
127spindle checkpoint (GO:0031577)2.84479122
128chromatin assembly (GO:0031497)2.84044655
129regulation of translational termination (GO:0006449)2.83966510
130mitotic sister chromatid cohesion (GO:0007064)2.83460963
131ribosomal small subunit biogenesis (GO:0042274)2.83131721
132regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.82072518

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.00202513
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.31834924
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.81469241
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.48148487
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.21646521
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.17444835
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.83369589
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83367674
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.54909902
10NELFA_20434984_ChIP-Seq_ESCs_Mouse2.47546818
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.47016270
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.42850837
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.29768311
14POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.25802821
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.23276106
16* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.21050485
17* ETS1_20019798_ChIP-Seq_JURKAT_Human2.17965354
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.15965121
19AR_21909140_ChIP-Seq_LNCAP_Human2.15871727
20XRN2_22483619_ChIP-Seq_HELA_Human2.14926379
21SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.14097350
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.10933480
23KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.10092073
24KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.10092073
25KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.10092073
26EGR1_19374776_ChIP-ChIP_THP-1_Human2.09582694
27* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.07694507
28NANOG_18555785_ChIP-Seq_MESCs_Mouse2.06500849
29* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.00286975
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.00014482
31HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.99667675
32E2F1_21310950_ChIP-Seq_MCF-7_Human1.95937204
33RBPJ_22232070_ChIP-Seq_NCS_Mouse1.95350778
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.95299203
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.94418623
36* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.91127686
37VDR_23849224_ChIP-Seq_CD4+_Human1.76406556
38STAT3_1855785_ChIP-Seq_MESCs_Mouse1.73802771
39POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.73378278
40TCF3_18692474_ChIP-Seq_MEFs_Mouse1.72494475
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.69685438
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67257566
43* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.65243422
44FOXP3_21729870_ChIP-Seq_TREG_Human1.64229702
45DCP1A_22483619_ChIP-Seq_HELA_Human1.61860913
46ZFX_18555785_ChIP-Seq_MESCs_Mouse1.60463109
47TTF2_22483619_ChIP-Seq_HELA_Human1.59590139
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55817706
49NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.51909668
50* GABP_19822575_ChIP-Seq_HepG2_Human1.49970216
51THAP11_20581084_ChIP-Seq_MESCs_Mouse1.49928388
52FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.49197800
53NANOG_16153702_ChIP-ChIP_HESCs_Human1.47395592
54* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.46945665
55POU5F1_16153702_ChIP-ChIP_HESCs_Human1.44099357
56SOX2_16153702_ChIP-ChIP_HESCs_Human1.42246624
57PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.42063099
58ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.40819874
59* ELK1_19687146_ChIP-ChIP_HELA_Human1.40133898
60HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.39536419
61ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36217348
62TCF3_18692474_ChIP-Seq_MESCs_Mouse1.35656635
63ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.34248951
64MYC_22102868_ChIP-Seq_BL_Human1.32685526
65KDM5A_27292631_Chip-Seq_BREAST_Human1.32606840
66NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.31174785
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.29147884
68KLF4_18555785_ChIP-Seq_MESCs_Mouse1.28689192
69CIITA_25753668_ChIP-Seq_RAJI_Human1.28477815
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.28377451
71ELF1_17652178_ChIP-ChIP_JURKAT_Human1.28231899
72SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.24966383
73E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.23853904
74HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23442939
75MYC_18940864_ChIP-ChIP_HL60_Human1.21720811
76KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.21114053
77* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19073584
78SOX17_20123909_ChIP-Seq_XEN_Mouse1.17293574
79NANOG_21062744_ChIP-ChIP_HESCs_Human1.17036519
80TFEB_21752829_ChIP-Seq_HELA_Human1.15540678
81TP63_19390658_ChIP-ChIP_HaCaT_Human1.15294515
82* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.14539595
83YY1_21170310_ChIP-Seq_MESCs_Mouse1.13911462
84TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.13898516
85FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12709024
86EWS_26573619_Chip-Seq_HEK293_Human1.11972573
87SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.11390203
88NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.09295093
89* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.07312732
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.06227568
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05995079
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.05105692
93HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03894583
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.03005520
95FUS_26573619_Chip-Seq_HEK293_Human1.02173908
96DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.01610987
97ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01595085
98CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00781125
99* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.99078571
100NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.98574645
101* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97117927
102SRF_21415370_ChIP-Seq_HL-1_Mouse0.96596889
103SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.96081186
104MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.95486434
105CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95486215
106* NANOG_18692474_ChIP-Seq_MEFs_Mouse0.95453536
107SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95203649
108E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95167622
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.94487815
110POU5F1_16518401_ChIP-PET_MESCs_Mouse0.93887194
111PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.91821955
112CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.91817899
113ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.87329818
114CHD1_26751641_Chip-Seq_LNCaP_Human0.78369404
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.74921846
116HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.74394635
117TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.73150942
118WT1_19549856_ChIP-ChIP_CCG9911_Human0.71202681
119IRF1_19129219_ChIP-ChIP_H3396_Human0.70791380

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.41241185
2MP0004957_abnormal_blastocyst_morpholog4.28048258
3* MP0010094_abnormal_chromosome_stability4.06922603
4MP0003806_abnormal_nucleotide_metabolis3.74642088
5MP0003111_abnormal_nucleus_morphology3.72346005
6MP0003077_abnormal_cell_cycle3.55480979
7MP0008057_abnormal_DNA_replication3.53810207
8MP0010352_gastrointestinal_tract_polyps2.99913282
9MP0003123_paternal_imprinting2.71843256
10* MP0008058_abnormal_DNA_repair2.51643475
11MP0008007_abnormal_cellular_replicative2.50261844
12MP0001730_embryonic_growth_arrest2.49597601
13MP0008932_abnormal_embryonic_tissue2.40315180
14MP0010030_abnormal_orbit_morphology2.38390619
15MP0000350_abnormal_cell_proliferation2.24254555
16MP0009697_abnormal_copulation2.09570068
17MP0002084_abnormal_developmental_patter1.90003288
18MP0005380_embryogenesis_phenotype1.88229825
19MP0001672_abnormal_embryogenesis/_devel1.88229825
20MP0010307_abnormal_tumor_latency1.85838448
21MP0001697_abnormal_embryo_size1.85455887
22MP0003890_abnormal_embryonic-extraembry1.85117746
23MP0002085_abnormal_embryonic_tissue1.85060452
24MP0003705_abnormal_hypodermis_morpholog1.81719070
25MP0008877_abnormal_DNA_methylation1.81357128
26MP0004133_heterotaxia1.72473169
27* MP0004197_abnormal_fetal_growth/weight/1.71620513
28MP0001293_anophthalmia1.69124250
29MP0003786_premature_aging1.65423148
30MP0003984_embryonic_growth_retardation1.65077984
31MP0002086_abnormal_extraembryonic_tissu1.64712437
32* MP0002080_prenatal_lethality1.64423314
33MP0002088_abnormal_embryonic_growth/wei1.62535049
34MP0009053_abnormal_anal_canal1.58521036
35MP0003121_genomic_imprinting1.57338028
36MP0002653_abnormal_ependyma_morphology1.51602391
37MP0004264_abnormal_extraembryonic_tissu1.50608558
38MP0000537_abnormal_urethra_morphology1.49112054
39MP0003283_abnormal_digestive_organ1.45314434
40MP0003941_abnormal_skin_development1.42511246
41MP0003567_abnormal_fetal_cardiomyocyte1.41178414
42MP0003119_abnormal_digestive_system1.37284757
43MP0002877_abnormal_melanocyte_morpholog1.37149785
44MP0005076_abnormal_cell_differentiation1.36785331
45MP0003718_maternal_effect1.27537358
46MP0002233_abnormal_nose_morphology1.24976436
47MP0006035_abnormal_mitochondrial_morpho1.21177280
48MP0005023_abnormal_wound_healing1.19229512
49* MP0000313_abnormal_cell_death1.11472995
50MP0002210_abnormal_sex_determination1.09827759
51MP0001529_abnormal_vocalization1.09557143
52MP0003937_abnormal_limbs/digits/tail_de1.09301893
53MP0002019_abnormal_tumor_incidence1.07874010
54MP0002396_abnormal_hematopoietic_system1.05971337
55MP0010234_abnormal_vibrissa_follicle1.05461512
56MP0002111_abnormal_tail_morphology1.05110332
57MP0002254_reproductive_system_inflammat1.04548652
58MP0009672_abnormal_birth_weight1.03178394
59MP0003566_abnormal_cell_adhesion1.03091309
60MP0000490_abnormal_crypts_of1.03087981
61MP0001145_abnormal_male_reproductive1.01825774
62MP0009703_decreased_birth_body1.00752615
63MP0001299_abnormal_eye_distance/1.00533706
64MP0000579_abnormal_nail_morphology0.99818745
65MP0003861_abnormal_nervous_system0.99104116
66MP0002009_preneoplasia0.98575346
67MP0004233_abnormal_muscle_weight0.97110914
68MP0003186_abnormal_redox_activity0.97090281
69MP0003221_abnormal_cardiomyocyte_apopto0.95840610
70MP0002751_abnormal_autonomic_nervous0.95569835
71MP0001286_abnormal_eye_development0.95405482
72MP0001849_ear_inflammation0.95189073
73MP0001188_hyperpigmentation0.94121613
74MP0005266_abnormal_metabolism0.88117116
75MP0002697_abnormal_eye_size0.88100483
76MP0000653_abnormal_sex_gland0.87718711
77MP0002092_abnormal_eye_morphology0.87494419
78MP0003385_abnormal_body_wall0.84940292
79MP0001915_intracranial_hemorrhage0.82622066
80MP0001929_abnormal_gametogenesis0.81113375
81MP0000358_abnormal_cell_content/0.80911470
82MP0000516_abnormal_urinary_system0.80745736
83MP0005367_renal/urinary_system_phenotyp0.80745736
84MP0001346_abnormal_lacrimal_gland0.79895600
85MP0002269_muscular_atrophy0.77881433
86MP0002160_abnormal_reproductive_system0.77795377
87MP0000566_synostosis0.77768406
88MP0008789_abnormal_olfactory_epithelium0.77694113
89MP0006292_abnormal_olfactory_placode0.77337336
90MP0003315_abnormal_perineum_morphology0.77321139
91MP0002249_abnormal_larynx_morphology0.76961264
92MP0001177_atelectasis0.76703694
93MP0000647_abnormal_sebaceous_gland0.76208376
94MP0005389_reproductive_system_phenotype0.75905876
95MP0002102_abnormal_ear_morphology0.74772620
96MP0002796_impaired_skin_barrier0.74360119
97MP0005499_abnormal_olfactory_system0.73357902
98MP0005394_taste/olfaction_phenotype0.73357902
99MP0000371_diluted_coat_color0.71583378
100MP0001119_abnormal_female_reproductive0.71551441
101MP0003122_maternal_imprinting0.71297010
102MP0000432_abnormal_head_morphology0.71038943
103MP0005384_cellular_phenotype0.70474042
104MP0003942_abnormal_urinary_system0.70402317
105MP0000428_abnormal_craniofacial_morphol0.70056831
106MP0006054_spinal_hemorrhage0.69774519
107MP0002932_abnormal_joint_morphology0.69017618
108MP0003755_abnormal_palate_morphology0.68949854
109MP0003935_abnormal_craniofacial_develop0.67864560
110MP0002081_perinatal_lethality0.67102108
111MP0002938_white_spotting0.66901877
112MP0001661_extended_life_span0.66845596
113MP0000762_abnormal_tongue_morphology0.65971710
114MP0003136_yellow_coat_color0.65053410
115MP0003943_abnormal_hepatobiliary_system0.65009379
116MP0000049_abnormal_middle_ear0.64979085
117MP0003936_abnormal_reproductive_system0.64899234
118MP0005501_abnormal_skin_physiology0.64166201
119MP0000678_abnormal_parathyroid_gland0.64043985
120MP0004272_abnormal_basement_membrane0.63893498
121MP0000477_abnormal_intestine_morphology0.62978622
122MP0004808_abnormal_hematopoietic_stem0.62581869
123MP0005621_abnormal_cell_physiology0.62363713
124MP0002075_abnormal_coat/hair_pigmentati0.62178088
125MP0003115_abnormal_respiratory_system0.61146203
126MP0001919_abnormal_reproductive_system0.59625027
127* MP0005391_vision/eye_phenotype0.59549217
128MP0000733_abnormal_muscle_development0.59376074
129MP0005187_abnormal_penis_morphology0.58941681
130MP0005248_abnormal_Harderian_gland0.58697031
131MP0002925_abnormal_cardiovascular_devel0.58491551

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.84835086
2Birth length less than 3rd percentile (HP:0003561)4.32961327
3Medulloblastoma (HP:0002885)4.22302657
4Colon cancer (HP:0003003)4.06393531
5Rhabdomyosarcoma (HP:0002859)3.80330952
6Selective tooth agenesis (HP:0001592)3.75136376
7Abnormality of the labia minora (HP:0012880)3.47087963
8Cortical dysplasia (HP:0002539)3.43377904
9Astrocytoma (HP:0009592)3.35547471
10Abnormality of the astrocytes (HP:0100707)3.35547471
11Breast hypoplasia (HP:0003187)3.32991355
12Embryonal renal neoplasm (HP:0011794)3.32462107
13Neoplasm of the oral cavity (HP:0100649)3.20488301
14Agnosia (HP:0010524)3.19679688
15Reticulocytopenia (HP:0001896)3.15603354
16Biliary tract neoplasm (HP:0100574)3.03502509
17Chromsome breakage (HP:0040012)2.97458587
18Degeneration of anterior horn cells (HP:0002398)2.96540314
19Abnormality of the anterior horn cell (HP:0006802)2.96540314
20Glioma (HP:0009733)2.91507317
21Neoplasm of striated muscle (HP:0009728)2.88137657
22Patellar aplasia (HP:0006443)2.86535596
23Carpal bone hypoplasia (HP:0001498)2.81966662
24Oral leukoplakia (HP:0002745)2.78117796
25Absent radius (HP:0003974)2.74473444
26Supernumerary spleens (HP:0009799)2.71999382
27Basal cell carcinoma (HP:0002671)2.71205689
28Abnormality of chromosome stability (HP:0003220)2.67537650
29Aplasia/Hypoplasia of the patella (HP:0006498)2.66635456
30Chromosomal breakage induced by crosslinking agents (HP:0003221)2.64004102
31Absent forearm bone (HP:0003953)2.61196129
32Aplasia involving forearm bones (HP:0009822)2.61196129
33Missing ribs (HP:0000921)2.59751059
34Abnormal number of incisors (HP:0011064)2.54649905
35Meckel diverticulum (HP:0002245)2.45641773
36Esophageal atresia (HP:0002032)2.45418566
37Proximal placement of thumb (HP:0009623)2.44090607
38Deviation of the thumb (HP:0009603)2.43023845
39Absent thumb (HP:0009777)2.42517291
40Aplasia/hypoplasia of the humerus (HP:0006507)2.41938257
41Abnormality of the carotid arteries (HP:0005344)2.41139870
42Volvulus (HP:0002580)2.37440677
43Abnormality of pyrimidine metabolism (HP:0004353)2.36900988
44Abnormality of the ileum (HP:0001549)2.35286612
45Neoplasm of the pancreas (HP:0002894)2.35198461
46Microvesicular hepatic steatosis (HP:0001414)2.31581319
47Angiofibromas (HP:0010615)2.31427224
48Adenoma sebaceum (HP:0009720)2.31427224
49Impulsivity (HP:0100710)2.30310194
50Ovarian neoplasm (HP:0100615)2.29258423
51Abnormality of methionine metabolism (HP:0010901)2.27279553
52Atresia of the external auditory canal (HP:0000413)2.26138110
53Rib fusion (HP:0000902)2.25484114
54Aplasia/Hypoplasia of the uvula (HP:0010293)2.24481258
55Abnormal biliary tract morphology (HP:0012440)2.21937509
56Amaurosis fugax (HP:0100576)2.19260473
57Triphalangeal thumb (HP:0001199)2.16942939
58Abnormality of the preputium (HP:0100587)2.16598803
59Short humerus (HP:0005792)2.15360326
60Shawl scrotum (HP:0000049)2.14756272
61Spastic diplegia (HP:0001264)2.14665442
62Aplasia/Hypoplasia of the sternum (HP:0006714)2.12607840
63Neoplasm of the rectum (HP:0100743)2.12221335
64Small intestinal stenosis (HP:0012848)2.11714533
65Duodenal stenosis (HP:0100867)2.11714533
6611 pairs of ribs (HP:0000878)2.09953169
67Abnormal lung lobation (HP:0002101)2.09777848
68Abnormality of the salivary glands (HP:0010286)2.09305720
69Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.09154700
70Trismus (HP:0000211)2.08717001
71Stenosis of the external auditory canal (HP:0000402)2.04842019
72Horseshoe kidney (HP:0000085)2.03557378
73Embryonal neoplasm (HP:0002898)2.00921504
74Hepatoblastoma (HP:0002884)2.00830729
75Pancreatic islet-cell hyperplasia (HP:0004510)2.00803320
76Abdominal situs inversus (HP:0003363)2.00603557
77Abnormality of abdominal situs (HP:0011620)2.00603557
78Neoplasm of the colon (HP:0100273)2.00118690
79Abnormality of the duodenum (HP:0002246)1.99138795
80Bifid tongue (HP:0010297)1.97948520
81Increased nuchal translucency (HP:0010880)1.97837335
82Abnormality of cells of the erythroid lineage (HP:0012130)1.97072389
83Rough bone trabeculation (HP:0100670)1.96757391
84Neoplasm of the adrenal gland (HP:0100631)1.96290397
85Myelodysplasia (HP:0002863)1.95658638
86Gastrointestinal carcinoma (HP:0002672)1.93626340
87Malignant gastrointestinal tract tumors (HP:0006749)1.93626340
88Neoplasm of the adrenal cortex (HP:0100641)1.93559852
89Gastrointestinal atresia (HP:0002589)1.92887343
90Intestinal polyp (HP:0005266)1.92044587
91Abnormality of glycolysis (HP:0004366)1.91228148
92Premature graying of hair (HP:0002216)1.90795900
93Sloping forehead (HP:0000340)1.90414828
94Cafe-au-lait spot (HP:0000957)1.90383290
95Ectopic kidney (HP:0000086)1.89945485
96Choanal atresia (HP:0000453)1.89300054
97Intestinal polyposis (HP:0200008)1.89292388
98Metaphyseal cupping (HP:0003021)1.89130894
99Increased hepatocellular lipid droplets (HP:0006565)1.87610728
100Neoplasm of the small intestine (HP:0100833)1.87282677
101Increased serum pyruvate (HP:0003542)1.86157440
102Facial cleft (HP:0002006)1.85262041
103Facial hemangioma (HP:0000329)1.85084800
104High anterior hairline (HP:0009890)1.84044626
105Freckling (HP:0001480)1.83332973
106Shoulder girdle muscle weakness (HP:0003547)1.83111319
107Hemivertebrae (HP:0002937)1.81908989
108Spinal muscular atrophy (HP:0007269)1.81350059
109Supernumerary bones of the axial skeleton (HP:0009144)1.80753017
110Clubbing of toes (HP:0100760)1.80131017
111Premature ovarian failure (HP:0008209)1.79942840
112Vertebral clefting (HP:0008428)1.79362933
113Breast carcinoma (HP:0003002)1.79309800
114Macrocytic anemia (HP:0001972)1.79197896
115Intestinal atresia (HP:0011100)1.78930401
116Abnormal hair whorl (HP:0010721)1.78894342
117Bilateral microphthalmos (HP:0007633)1.78554571
118Abnormality of the septum pellucidum (HP:0007375)1.77137083
119Uterine neoplasm (HP:0010784)1.76039548
120Septo-optic dysplasia (HP:0100842)1.75226911
121Skull defect (HP:0001362)1.74798120
122Postnatal microcephaly (HP:0005484)1.73828627
123Neuroblastic tumors (HP:0004376)1.73076552
124Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.73076552
125Neuroblastoma (HP:0003006)1.73076552
126Primitive neuroectodermal tumor (HP:0030065)1.73076552
127Multiple enchondromatosis (HP:0005701)1.72812390
128Megaloblastic anemia (HP:0001889)1.71962369
129Nephroblastoma (Wilms tumor) (HP:0002667)1.70021249
130Progressive external ophthalmoplegia (HP:0000590)1.70003944
131Pallor (HP:0000980)1.69144688
132Abnormality of aspartate family amino acid metabolism (HP:0010899)1.68127568
133Aplastic anemia (HP:0001915)1.67996213
134Squamous cell carcinoma (HP:0002860)1.66195916
135Duplication of thumb phalanx (HP:0009942)1.65431456
136Overlapping toe (HP:0001845)1.63823758
137Arteriovenous malformation (HP:0100026)1.61489345
138Abnormality of serum amino acid levels (HP:0003112)1.61254699
139Generalized hypotonia (HP:0001290)1.61182643
140Aplasia/Hypoplasia of the sacrum (HP:0008517)1.60710643
141Tracheoesophageal fistula (HP:0002575)1.59730705
142Cellular immunodeficiency (HP:0005374)1.59036062
143Hypoglycemic seizures (HP:0002173)1.58366220
144Deep philtrum (HP:0002002)1.57569467
145Leiomyosarcoma (HP:0100243)1.56603820
146Uterine leiomyosarcoma (HP:0002891)1.56603820
147Hypoplastic pelvis (HP:0008839)1.55089777

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.32831517
2WEE13.89000877
3BUB13.32129224
4CDK122.77016605
5NEK12.73966534
6PASK2.69666773
7RPS6KB22.66998624
8EPHA22.56126057
9TTK2.52995217
10EIF2AK12.50381893
11VRK22.46429817
12TAF12.33793992
13NEK22.17002730
14TSSK62.14370863
15SRPK12.13364680
16EEF2K2.06700939
17ACVR1B2.02256743
18PLK11.92075946
19BRSK21.90130698
20FLT31.79755732
21CDK71.76206805
22PLK31.72056146
23ATR1.71896483
24PKN21.65070218
25TRIM281.63698454
26SCYL21.62718824
27AURKB1.62256389
28MAPKAPK31.45472986
29STK101.41822547
30EIF2AK31.39963964
31MAP3K81.38698291
32CHEK11.37432542
33TESK21.36563383
34TNIK1.35915828
35PAK41.33165212
36CHEK21.32585183
37PLK41.31098939
38TGFBR11.30917813
39STK38L1.30731593
40PNCK1.30720057
41MAP3K101.30006057
42BRD41.26548841
43MKNK11.26200165
44CDK41.26011112
45TLK11.25920247
46VRK11.20850752
47DYRK31.19889796
48NUAK11.19361455
49LATS11.17266283
50AURKA1.17086946
51STK161.16682182
52BRSK11.12896109
53SMG11.12191944
54RPS6KA41.11444389
55BCR1.09443064
56ALK1.09409927
57ATM1.08899511
58EIF2AK21.07812962
59BCKDK1.07605178
60MET1.06031527
61CDK61.04290033
62NME21.00404360
63CDK20.97271405
64NME10.91814495
65STK40.88544641
66MTOR0.87357949
67LATS20.85870937
68LRRK20.77511122
69PRKCI0.76242925
70MKNK20.75888679
71FGFR10.72882597
72MELK0.72880997
73* CSNK2A20.72522425
74ERBB30.72212638
75PDK40.70937355
76PDK30.70937355
77CDK10.69543696
78CSNK1G10.68941415
79STK30.65396318
80AKT30.65084467
81BMPR1B0.64035760
82CSNK1E0.62647931
83PLK20.62059550
84PIM10.62047451
85CLK10.61737953
86ZAK0.61197962
87MST40.61087956
88CDK190.56752119
89CSNK2A10.56349605
90WNK30.54613264
91CCNB10.54469026
92CSNK1D0.52496881
93CDK80.51921917
94MAP3K40.50394150
95FGFR20.49928153
96PBK0.48413162
97TESK10.47617100
98CSNK1G30.46823734
99YES10.46214970
100PAK10.45701754
101* PRKDC0.45390893
102PAK20.44371639
103MAP3K30.41186662
104CDK180.41078847
105CSNK1G20.39693888
106DAPK10.39646435
107PDK20.39497062
108CSNK1A1L0.38936239
109MAP2K30.37414119
110MAPK140.36717375
111CDK150.35935362
112AKT20.35552703
113STK240.35450217
114TTN0.35386439
115RPS6KA50.34499639
116CDK140.34248595
117CDK11A0.34120243
118CDK30.33897871
119MAPK10.32200766
120CDK90.30594465
121ERBB40.30563428
122ILK0.28270208
123TAOK20.27862886
124CASK0.27138785
125PDGFRA0.25962223
126GSK3B0.25389186
127NLK0.24412166
128RPS6KB10.24399925
129BRAF0.24396459
130AKT10.24111450
131MINK10.23268644
132DYRK20.22662838
133PTK60.21042838
134DYRK1B0.20886347
135MAPK110.20086089

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.44629993
2DNA replication_Homo sapiens_hsa030304.44127520
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.64635772
4One carbon pool by folate_Homo sapiens_hsa006703.55554418
5RNA transport_Homo sapiens_hsa030133.23243526
6Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.21609170
7Spliceosome_Homo sapiens_hsa030403.09801668
8Nucleotide excision repair_Homo sapiens_hsa034202.78040240
9Ribosome_Homo sapiens_hsa030102.69407021
10Cell cycle_Homo sapiens_hsa041102.56789850
11Homologous recombination_Homo sapiens_hsa034402.54934418
12RNA polymerase_Homo sapiens_hsa030202.48567945
13Base excision repair_Homo sapiens_hsa034102.46878392
14Proteasome_Homo sapiens_hsa030502.29265044
15Pyrimidine metabolism_Homo sapiens_hsa002402.06965673
16Fanconi anemia pathway_Homo sapiens_hsa034602.05856228
17RNA degradation_Homo sapiens_hsa030181.86727744
18Selenocompound metabolism_Homo sapiens_hsa004501.79323761
19mRNA surveillance pathway_Homo sapiens_hsa030151.75232905
20Biosynthesis of amino acids_Homo sapiens_hsa012301.58418706
21Basal transcription factors_Homo sapiens_hsa030221.57678018
22Cyanoamino acid metabolism_Homo sapiens_hsa004601.52952012
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.52824560
24p53 signaling pathway_Homo sapiens_hsa041151.48562246
25Systemic lupus erythematosus_Homo sapiens_hsa053221.34793299
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.33042778
27* Non-homologous end-joining_Homo sapiens_hsa034501.32951807
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.30934220
29Steroid biosynthesis_Homo sapiens_hsa001001.30462044
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.22293438
31Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.20930467
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.19407964
33Vitamin B6 metabolism_Homo sapiens_hsa007501.19245775
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.04111934
35Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.03952359
36Carbon metabolism_Homo sapiens_hsa012001.02449258
37Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.98780237
38Folate biosynthesis_Homo sapiens_hsa007900.98657822
39Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.97093859
40Viral carcinogenesis_Homo sapiens_hsa052030.95792178
41Purine metabolism_Homo sapiens_hsa002300.95450027
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.93932654
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.88924409
44Fatty acid elongation_Homo sapiens_hsa000620.87306109
45Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.86990082
46Epstein-Barr virus infection_Homo sapiens_hsa051690.86092806
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79088132
48Oocyte meiosis_Homo sapiens_hsa041140.78787565
49Glutathione metabolism_Homo sapiens_hsa004800.77534410
50Basal cell carcinoma_Homo sapiens_hsa052170.76745276
51Parkinsons disease_Homo sapiens_hsa050120.76615927
52Hippo signaling pathway_Homo sapiens_hsa043900.76172324
53Thyroid cancer_Homo sapiens_hsa052160.74852091
54Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.73179483
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.73042116
56Huntingtons disease_Homo sapiens_hsa050160.72981767
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68625707
58TGF-beta signaling pathway_Homo sapiens_hsa043500.68422313
59Pyruvate metabolism_Homo sapiens_hsa006200.68391409
60Antigen processing and presentation_Homo sapiens_hsa046120.67709289
61Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67219115
62Pentose phosphate pathway_Homo sapiens_hsa000300.64703266
63Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.63574012
64HTLV-I infection_Homo sapiens_hsa051660.61682483
65MicroRNAs in cancer_Homo sapiens_hsa052060.61679006
66Lysine degradation_Homo sapiens_hsa003100.61129402
67Sulfur relay system_Homo sapiens_hsa041220.60005629
68Oxidative phosphorylation_Homo sapiens_hsa001900.59822037
69Nitrogen metabolism_Homo sapiens_hsa009100.59821734
70N-Glycan biosynthesis_Homo sapiens_hsa005100.59089602
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58291130
72Fructose and mannose metabolism_Homo sapiens_hsa000510.54928859
73Hedgehog signaling pathway_Homo sapiens_hsa043400.50879042
74Fatty acid metabolism_Homo sapiens_hsa012120.50816389
75Arginine and proline metabolism_Homo sapiens_hsa003300.48946409
76Maturity onset diabetes of the young_Homo sapiens_hsa049500.48804926
77Tyrosine metabolism_Homo sapiens_hsa003500.48333205
78Arginine biosynthesis_Homo sapiens_hsa002200.48117497
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.47535851
80Small cell lung cancer_Homo sapiens_hsa052220.47472655
81Herpes simplex infection_Homo sapiens_hsa051680.44124282
82Adherens junction_Homo sapiens_hsa045200.43877358
83Galactose metabolism_Homo sapiens_hsa000520.42446370
84Alcoholism_Homo sapiens_hsa050340.40714398
85Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.39375165
86Bladder cancer_Homo sapiens_hsa052190.37977093
87Phenylalanine metabolism_Homo sapiens_hsa003600.36036802
88Notch signaling pathway_Homo sapiens_hsa043300.33892665
89Protein export_Homo sapiens_hsa030600.32921952
90Propanoate metabolism_Homo sapiens_hsa006400.32595131
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30357342
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30194802
93Colorectal cancer_Homo sapiens_hsa052100.30103074
94mTOR signaling pathway_Homo sapiens_hsa041500.29380153
95Tryptophan metabolism_Homo sapiens_hsa003800.28651877
96Tight junction_Homo sapiens_hsa045300.28363271
97Chemical carcinogenesis_Homo sapiens_hsa052040.27859451
98Fatty acid degradation_Homo sapiens_hsa000710.27655855
99Alzheimers disease_Homo sapiens_hsa050100.27277075
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.26916496
101Primary bile acid biosynthesis_Homo sapiens_hsa001200.22864413
102Metabolic pathways_Homo sapiens_hsa011000.22376530
103Legionellosis_Homo sapiens_hsa051340.21177574
104Pentose and glucuronate interconversions_Homo sapiens_hsa000400.20206785
105Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.19830970
106Vitamin digestion and absorption_Homo sapiens_hsa049770.19771914
107Pathways in cancer_Homo sapiens_hsa052000.18146703
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.16739545
109Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.15926813
110Renin-angiotensin system_Homo sapiens_hsa046140.11134368
111Wnt signaling pathway_Homo sapiens_hsa043100.10865674
112Melanoma_Homo sapiens_hsa052180.10138982
113Prostate cancer_Homo sapiens_hsa052150.09737277
114Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.08230293
115Proteoglycans in cancer_Homo sapiens_hsa052050.07855808
116beta-Alanine metabolism_Homo sapiens_hsa004100.07697574
117Butanoate metabolism_Homo sapiens_hsa006500.06154340
118Endometrial cancer_Homo sapiens_hsa052130.05368259
119Peroxisome_Homo sapiens_hsa041460.05356317
120Chronic myeloid leukemia_Homo sapiens_hsa052200.04559312

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