XXYLT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)3.97134537
2regulation of translational fidelity (GO:0006450)3.83044517
3paraxial mesoderm development (GO:0048339)3.49305660
4establishment of integrated proviral latency (GO:0075713)3.38400706
5planar cell polarity pathway involved in neural tube closure (GO:0090179)3.37194188
6glucocorticoid receptor signaling pathway (GO:0042921)3.36763836
7G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.32797640
8COPI coating of Golgi vesicle (GO:0048205)3.30987576
9Golgi transport vesicle coating (GO:0048200)3.30987576
10nuclear pore organization (GO:0006999)3.24824911
11DNA strand elongation involved in DNA replication (GO:0006271)3.21993873
12DNA strand elongation (GO:0022616)3.20699002
13pre-miRNA processing (GO:0031054)3.20236537
14folic acid-containing compound biosynthetic process (GO:0009396)3.18997540
15nuclear pore complex assembly (GO:0051292)3.18060300
16chondrocyte proliferation (GO:0035988)3.14494427
17heterochromatin organization (GO:0070828)3.14350516
18protein heterotrimerization (GO:0070208)3.10128746
19protein localization to chromosome, centromeric region (GO:0071459)3.04625817
20regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.03102922
21negative regulation of fatty acid transport (GO:2000192)3.01151235
22polarized epithelial cell differentiation (GO:0030859)3.01069029
23positive regulation of histone deacetylation (GO:0031065)2.98978984
24histone arginine methylation (GO:0034969)2.88088634
25negative regulation of phagocytosis (GO:0050765)2.86174067
26endodermal cell differentiation (GO:0035987)2.84847373
27Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.83885588
28negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.82188104
29deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.81549545
30IMP biosynthetic process (GO:0006188)2.80602801
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.80303178
32antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.80303178
33negative regulation of histone acetylation (GO:0035067)2.77981577
34adherens junction assembly (GO:0034333)2.77462140
35protein retention in ER lumen (GO:0006621)2.76957492
36DNA topological change (GO:0006265)2.76884470
37mitotic sister chromatid segregation (GO:0000070)2.74919778
38maturation of SSU-rRNA (GO:0030490)2.73618422
39embryonic process involved in female pregnancy (GO:0060136)2.73481758
40regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.72923043
41antigen processing and presentation of endogenous antigen (GO:0019883)2.70967117
42establishment of viral latency (GO:0019043)2.70719049
43stress fiber assembly (GO:0043149)2.70668308
44telomere maintenance via semi-conservative replication (GO:0032201)2.70272841
45sister chromatid segregation (GO:0000819)2.70064222
46regulation of establishment of planar polarity (GO:0090175)2.70041007
47negative regulation of cell size (GO:0045792)2.69611318
48IMP metabolic process (GO:0046040)2.69552547
49cytoskeletal anchoring at plasma membrane (GO:0007016)2.68570577
50convergent extension (GO:0060026)2.68135922
51chromatin remodeling at centromere (GO:0031055)2.67242430
52corticosteroid receptor signaling pathway (GO:0031958)2.66373486
53cochlea morphogenesis (GO:0090103)2.65968171
54cortical actin cytoskeleton organization (GO:0030866)2.65584609
55DNA ligation (GO:0006266)2.65233320
56negative regulation of focal adhesion assembly (GO:0051895)2.65084167
57negative regulation of cell junction assembly (GO:1901889)2.65084167
58negative regulation of adherens junction organization (GO:1903392)2.65084167
59vascular endothelial growth factor signaling pathway (GO:0038084)2.64152109
60apoptotic cell clearance (GO:0043277)2.63573845
61negative regulation of chondrocyte differentiation (GO:0032331)2.63303749
62maternal placenta development (GO:0001893)2.63243300
63protein localization to kinetochore (GO:0034501)2.62322935
64alternative mRNA splicing, via spliceosome (GO:0000380)2.61082667
65L-serine metabolic process (GO:0006563)2.61076060
66mitotic metaphase plate congression (GO:0007080)2.60255665
67protein-DNA complex disassembly (GO:0032986)2.60102982
68nucleosome disassembly (GO:0006337)2.60102982
69regulation of translational termination (GO:0006449)2.58667077
70CENP-A containing nucleosome assembly (GO:0034080)2.58596749
71collagen fibril organization (GO:0030199)2.58475860
72regulation of mammary gland epithelial cell proliferation (GO:0033599)2.58404398
73T cell apoptotic process (GO:0070231)2.57790555
74positive regulation of endothelial cell apoptotic process (GO:2000353)2.55069142
75membrane disassembly (GO:0030397)2.54815801
76nuclear envelope disassembly (GO:0051081)2.54815801
77plasma membrane repair (GO:0001778)2.53392248
78pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.50965456
79mitotic nuclear envelope disassembly (GO:0007077)2.50823555
80bone trabecula formation (GO:0060346)2.50543176
81positive regulation of SMAD protein import into nucleus (GO:0060391)2.50136303
82positive regulation of cell cycle G2/M phase transition (GO:1902751)2.50016823
83positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.50016823
84non-canonical Wnt signaling pathway (GO:0035567)2.49314370
85cell migration involved in sprouting angiogenesis (GO:0002042)2.49249033
86peptidyl-arginine omega-N-methylation (GO:0035247)2.48762865
87positive regulation of protein deacetylation (GO:0090312)2.47969268
88insulin-like growth factor receptor signaling pathway (GO:0048009)2.45916220
89positive regulation of fibroblast migration (GO:0010763)2.45861726
90cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.44023941
91lens fiber cell development (GO:0070307)2.42706047
92protein localization to endosome (GO:0036010)2.42280192
93nucleobase biosynthetic process (GO:0046112)2.41892175
94positive regulation of blood vessel endothelial cell migration (GO:0043536)2.41455034
95peptidyl-arginine methylation (GO:0018216)2.40819208
96peptidyl-arginine N-methylation (GO:0035246)2.40819208
97mitotic chromosome condensation (GO:0007076)2.40344128
98axon extension involved in axon guidance (GO:0048846)2.39438468
99neuron projection extension involved in neuron projection guidance (GO:1902284)2.39438468
100regulation of SMAD protein import into nucleus (GO:0060390)2.38815770
101outer ear morphogenesis (GO:0042473)2.38707770
102DNA strand renaturation (GO:0000733)2.38462596
103pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.37036335
104kinetochore organization (GO:0051383)2.36778170
105negative regulation of catenin import into nucleus (GO:0035414)2.36344122
106regulation of posttranscriptional gene silencing (GO:0060147)2.36101567
107regulation of gene silencing by miRNA (GO:0060964)2.36101567
108regulation of gene silencing by RNA (GO:0060966)2.36101567
109hippo signaling (GO:0035329)2.36018884
110ribosomal small subunit biogenesis (GO:0042274)2.35957012
111skin morphogenesis (GO:0043589)2.35629924
112apoptotic process involved in morphogenesis (GO:0060561)2.35602849
113regulation of sister chromatid cohesion (GO:0007063)2.35067276
114germ cell migration (GO:0008354)2.34520615
115negative regulation of histone methylation (GO:0031061)2.34190624
116sequestering of extracellular ligand from receptor (GO:0035581)2.34146287
117heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.33361872
118protein maturation by protein folding (GO:0022417)2.33170535
119negative regulation of RNA splicing (GO:0033119)2.33010588
120mitotic recombination (GO:0006312)2.32862846
121lymphocyte apoptotic process (GO:0070227)2.32097849
122DNA replication checkpoint (GO:0000076)2.31744978
123regulation of stem cell maintenance (GO:2000036)2.31386080
124regulation of double-strand break repair via homologous recombination (GO:0010569)2.30890798
125peptidyl-lysine dimethylation (GO:0018027)2.30226887
126maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.29797850
127DNA replication initiation (GO:0006270)2.29567250
128positive regulation of RNA splicing (GO:0033120)2.29561756
129mRNA stabilization (GO:0048255)2.28446730
130RNA stabilization (GO:0043489)2.28446730
131mitotic cytokinesis (GO:0000281)2.28363922
132positive regulation of epithelial to mesenchymal transition (GO:0010718)2.28019325
133negative regulation of embryonic development (GO:0045992)2.27571142
134DNA duplex unwinding (GO:0032508)2.27482325
135metaphase plate congression (GO:0051310)2.26785932
136pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.25493918
137formation of translation preinitiation complex (GO:0001731)2.25127889
138negative regulation of vascular permeability (GO:0043116)2.24829398
139nuclear envelope reassembly (GO:0031468)2.24417810
140mitotic nuclear envelope reassembly (GO:0007084)2.24417810
141negative regulation of mRNA processing (GO:0050686)2.24322760
142chromatin assembly (GO:0031497)2.23692814
143NLS-bearing protein import into nucleus (GO:0006607)2.23640535
144purine nucleobase biosynthetic process (GO:0009113)2.23558842
145focal adhesion assembly (GO:0048041)2.22086169
146cell-substrate adherens junction assembly (GO:0007045)2.22086169
147DNA geometric change (GO:0032392)2.21702085
148response to laminar fluid shear stress (GO:0034616)2.20860415
149notochord development (GO:0030903)2.20602920
150receptor catabolic process (GO:0032801)2.20002308
151pore complex assembly (GO:0046931)2.19049896
152somatic stem cell division (GO:0048103)2.18504591
153regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.17829841
154telomere maintenance via recombination (GO:0000722)2.17760359
155DNA replication-independent nucleosome organization (GO:0034724)2.16636629
156DNA replication-independent nucleosome assembly (GO:0006336)2.16636629
157base-excision repair (GO:0006284)2.16058646
158regulation of double-strand break repair (GO:2000779)2.15932302
159protein localization to chromosome (GO:0034502)2.15477841
160positive regulation of DNA-dependent DNA replication (GO:2000105)2.13809176
161kinetochore assembly (GO:0051382)2.11368940
162establishment of planar polarity (GO:0001736)2.11122597
163establishment of tissue polarity (GO:0007164)2.11122597
164chromatin assembly or disassembly (GO:0006333)2.10738113
165embryonic skeletal joint morphogenesis (GO:0060272)2.10252842
166ATP-dependent chromatin remodeling (GO:0043044)2.09949962
167basement membrane organization (GO:0071711)2.09457898
168retina vasculature morphogenesis in camera-type eye (GO:0061299)2.08411422
169cell fate commitment involved in formation of primary germ layer (GO:0060795)2.07396186
170negative regulation of cell fate specification (GO:0009996)2.06987293
171pyrimidine nucleotide catabolic process (GO:0006244)2.06109941
172establishment of apical/basal cell polarity (GO:0035089)2.05934638
173heparan sulfate proteoglycan metabolic process (GO:0030201)2.04670165
174chondrocyte development (GO:0002063)2.02155678

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.28162885
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.05387383
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.99647215
4MYC_22102868_ChIP-Seq_BL_Human3.71498987
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.30741661
6HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.28495563
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.21954413
8RBPJ_22232070_ChIP-Seq_NCS_Mouse3.09470262
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.90055651
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.62464410
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.58221397
12VDR_21846776_ChIP-Seq_THP-1_Human2.43888558
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.41200085
14KDM2B_26808549_Chip-Seq_DND41_Human2.34691947
15KDM2B_26808549_Chip-Seq_SUP-B15_Human2.31981252
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.27497294
17ELK3_25401928_ChIP-Seq_HUVEC_Human2.23603523
18KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.23318079
19THAP11_20581084_ChIP-Seq_MESCs_Mouse2.20624694
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19903619
21TCF7_22412390_ChIP-Seq_EML_Mouse2.19453166
22KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.04362767
23ZFP281_18757296_ChIP-ChIP_E14_Mouse2.03348783
24STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.02561185
25MYC_18555785_ChIP-Seq_MESCs_Mouse2.01550832
26KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.01354522
27ZNF263_19887448_ChIP-Seq_K562_Human2.00083420
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.99787297
29WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.99486168
30ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.96709450
31RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.94869203
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.87889413
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.87399766
34E2F1_18555785_ChIP-Seq_MESCs_Mouse1.86808534
35CREB1_15753290_ChIP-ChIP_HEK293T_Human1.84866545
36GABP_19822575_ChIP-Seq_HepG2_Human1.84804918
37TP63_17297297_ChIP-ChIP_HaCaT_Human1.84470227
38TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.80606813
39ETS1_20019798_ChIP-Seq_JURKAT_Human1.80135834
40TRIM28_21343339_ChIP-Seq_HEK293_Human1.77282844
41CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.72549883
42TTF2_22483619_ChIP-Seq_HELA_Human1.72339517
43DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.72336667
44KDM2B_26808549_Chip-Seq_JURKAT_Human1.72289379
45ZFP281_27345836_Chip-Seq_ESCs_Mouse1.70952185
46MYC_19079543_ChIP-ChIP_MESCs_Mouse1.68204889
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.67211146
48P300_27058665_Chip-Seq_ZR-75-30cells_Human1.63974325
49LXR_22292898_ChIP-Seq_THP-1_Human1.63385426
50KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.60446688
51CLOCK_20551151_ChIP-Seq_293T_Human1.60364737
52NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.58548590
53DCP1A_22483619_ChIP-Seq_HELA_Human1.58153402
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.57911422
55UTX_26944678_Chip-Seq_JUKART_Human1.57657929
56SCL_19346495_ChIP-Seq_HPC-7_Human1.56074223
57ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.55060015
58POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.53769989
59PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.53610682
60SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.53336934
61EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46625068
62FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.46231714
63MAF_26560356_Chip-Seq_TH1_Human1.46116695
64ESR1_15608294_ChIP-ChIP_MCF-7_Human1.43639602
65TP63_19390658_ChIP-ChIP_HaCaT_Human1.42794664
66GABP_17652178_ChIP-ChIP_JURKAT_Human1.42677360
67ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.41934772
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41580661
69EST1_17652178_ChIP-ChIP_JURKAT_Human1.41159656
70E2F4_17652178_ChIP-ChIP_JURKAT_Human1.40052524
71YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39988129
72CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.39470025
73VDR_24763502_ChIP-Seq_THP-1_Human1.38030487
74SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.36858385
75KDM2B_26808549_Chip-Seq_K562_Human1.35633145
76SOX2_16153702_ChIP-ChIP_HESCs_Human1.34970161
77EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.33271227
78ATF3_27146783_Chip-Seq_COLON_Human1.32668388
79RACK7_27058665_Chip-Seq_MCF-7_Human1.32325459
80TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.31732072
81CIITA_25753668_ChIP-Seq_RAJI_Human1.30770297
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.28564658
83KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.28517005
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.27698528
85TP53_22127205_ChIP-Seq_IMR90_Human1.27367293
86MYB_26560356_Chip-Seq_TH2_Human1.27128686
87E2F1_21310950_ChIP-Seq_MCF-7_Human1.25087075
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24894915
89DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.24426854
90BRD4_27068464_Chip-Seq_AML-cells_Mouse1.24210770
91RARG_19884340_ChIP-ChIP_MEFs_Mouse1.23493228
92TFEB_21752829_ChIP-Seq_HELA_Human1.22920135
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.22194571
94FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.22088997
95MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.21464532
96KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.21183848
97POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.21021905
98ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21020678
99ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.20661264
100KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.20594139
101KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.20594139
102KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.20594139
103AR_21909140_ChIP-Seq_LNCAP_Human1.20082852
104NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.19102543
105NCOR1_26117541_ChIP-Seq_K562_Human1.18921043
106POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.18446784
107SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.18389391
108HIF1A_21447827_ChIP-Seq_MCF-7_Human1.17950196
109NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.17359483
110KDM5A_27292631_Chip-Seq_BREAST_Human1.16100391
111HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14488357
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.13679185
113ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12624744
114NANOG_21062744_ChIP-ChIP_HESCs_Human1.12036050
115TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.11650497
116ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11642662
117NANOG_16153702_ChIP-ChIP_HESCs_Human1.10734478
118EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.09963710
119CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09521267
120E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.09367727
121ELK1_19687146_ChIP-ChIP_HELA_Human1.08947296
122UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.08929690
123SPI1_23127762_ChIP-Seq_K562_Human1.08741104
124TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.08504623
125SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.08450253
126XRN2_22483619_ChIP-Seq_HELA_Human1.08333641
127TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08280743
128MYB_21317192_ChIP-Seq_ERMYB_Mouse1.07541336
129KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06715269
130STAT3_1855785_ChIP-Seq_MESCs_Mouse1.05879808
131CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.05836281
132CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05199681
133FOXP3_21729870_ChIP-Seq_TREG_Human1.04993745
134PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04917892
135DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04317831
136HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.03924501
137CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.03514610
138TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.03072506
139CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.01775684
140SRF_21415370_ChIP-Seq_HL-1_Mouse1.01490416
141FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.01394083
142WT1_19549856_ChIP-ChIP_CCG9911_Human1.01090224
143MYC_18940864_ChIP-ChIP_HL60_Human1.00400116
144POU5F1_16153702_ChIP-ChIP_HESCs_Human1.00174911
145* BRD4_25478319_ChIP-Seq_HGPS_Human1.00007129
146UBF1/2_26484160_Chip-Seq_HMECs_Human0.99756740
147TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98849736
148SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.98726432
149FOXP1_21924763_ChIP-Seq_HESCs_Human0.97153807
150SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.95723685
151SOX17_20123909_ChIP-Seq_XEN_Mouse0.95715834
152MYB_26560356_Chip-Seq_TH1_Human0.95382732
153PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94156393
154KLF4_18555785_ChIP-Seq_MESCs_Mouse0.93566151
155FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93343366
156ERG_20887958_ChIP-Seq_HPC-7_Mouse0.93106409
157KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92916781
158PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.92845771
159CTCF_18555785_ChIP-Seq_MESCs_Mouse0.92834471
160ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.92658827
161CHD1_26751641_Chip-Seq_LNCaP_Human0.92301193
162DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92199228
163PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90838734
164YY1_21170310_ChIP-Seq_MESCs_Mouse0.90809026
165TP53_20018659_ChIP-ChIP_R1E_Mouse0.86877544

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.85863523
2MP0003705_abnormal_hypodermis_morpholog4.77474181
3MP0010352_gastrointestinal_tract_polyps3.46145252
4MP0006054_spinal_hemorrhage3.27610057
5MP0005623_abnormal_meninges_morphology2.74083154
6MP0003279_aneurysm2.50568449
7MP0003300_gastrointestinal_ulcer2.37343115
8MP0005275_abnormal_skin_tensile2.36580739
9MP0002396_abnormal_hematopoietic_system2.14891598
10MP0006292_abnormal_olfactory_placode2.07073786
11MP0000566_synostosis2.04447527
12MP0005076_abnormal_cell_differentiation2.04206819
13MP0003566_abnormal_cell_adhesion2.01774373
14MP0001958_emphysema2.00190605
15MP0001293_anophthalmia1.97472750
16MP0008932_abnormal_embryonic_tissue1.95819982
17MP0001849_ear_inflammation1.86316478
18MP0003123_paternal_imprinting1.86145514
19MP0010094_abnormal_chromosome_stability1.81746150
20MP0003937_abnormal_limbs/digits/tail_de1.80611327
21MP0010368_abnormal_lymphatic_system1.80586143
22MP0004808_abnormal_hematopoietic_stem1.78242903
23MP0004272_abnormal_basement_membrane1.76416406
24MP0003136_yellow_coat_color1.76140536
25MP0005503_abnormal_tendon_morphology1.71705342
26MP0002938_white_spotting1.71091384
27MP0002877_abnormal_melanocyte_morpholog1.69995713
28MP0002697_abnormal_eye_size1.67939165
29MP0009379_abnormal_foot_pigmentation1.67593171
30MP0001348_abnormal_lacrimal_gland1.66936765
31MP0009250_abnormal_appendicular_skeleto1.62709588
32MP0000733_abnormal_muscle_development1.61635486
33MP0003315_abnormal_perineum_morphology1.59941383
34MP0003091_abnormal_cell_migration1.56597218
35MP0010030_abnormal_orbit_morphology1.54323748
36MP0003693_abnormal_embryo_hatching1.54171740
37MP0009278_abnormal_bone_marrow1.52229018
38MP0002092_abnormal_eye_morphology1.51120801
39MP0000428_abnormal_craniofacial_morphol1.50823059
40MP0003755_abnormal_palate_morphology1.48389278
41MP0005023_abnormal_wound_healing1.45306461
42MP0005171_absent_coat_pigmentation1.45250074
43MP0003941_abnormal_skin_development1.44511640
44MP0004957_abnormal_blastocyst_morpholog1.44121860
45MP0004197_abnormal_fetal_growth/weight/1.40906651
46MP0000762_abnormal_tongue_morphology1.39291624
47MP0002233_abnormal_nose_morphology1.37561660
48MP0001730_embryonic_growth_arrest1.36459002
49MP0001286_abnormal_eye_development1.35895819
50MP0002111_abnormal_tail_morphology1.35779818
51MP0008789_abnormal_olfactory_epithelium1.33766997
52MP0003303_peritoneal_inflammation1.33451514
53MP0010307_abnormal_tumor_latency1.32898067
54MP0003283_abnormal_digestive_organ1.28586323
55MP0002089_abnormal_postnatal_growth/wei1.26351814
56MP0003172_abnormal_lysosome_physiology1.25667005
57MP0004133_heterotaxia1.24166646
58MP0000350_abnormal_cell_proliferation1.23610800
59MP0003385_abnormal_body_wall1.23164974
60MP0009384_cardiac_valve_regurgitation1.22218472
61MP0005197_abnormal_uvea_morphology1.19622080
62MP0008007_abnormal_cellular_replicative1.18913344
63MP0002084_abnormal_developmental_patter1.18430525
64MP0005174_abnormal_tail_pigmentation1.18202385
65MP0002282_abnormal_trachea_morphology1.18161701
66MP0005508_abnormal_skeleton_morphology1.16074811
67MP0004858_abnormal_nervous_system1.15140066
68MP0004233_abnormal_muscle_weight1.14059373
69MP0001879_abnormal_lymphatic_vessel1.12675692
70MP0002925_abnormal_cardiovascular_devel1.12319620
71MP0002234_abnormal_pharynx_morphology1.12068755
72MP0004859_abnormal_synaptic_plasticity1.11624616
73MP0001697_abnormal_embryo_size1.10840595
74MP0002086_abnormal_extraembryonic_tissu1.09515374
75MP0008058_abnormal_DNA_repair1.09461681
76MP0000432_abnormal_head_morphology1.08577376
77MP0003119_abnormal_digestive_system1.07514620
78MP0005257_abnormal_intraocular_pressure1.06251758
79MP0010234_abnormal_vibrissa_follicle1.05944525
80MP0002896_abnormal_bone_mineralization1.05795362
81MP0003861_abnormal_nervous_system1.02996999
82MP0009697_abnormal_copulation1.01685055
83MP0002085_abnormal_embryonic_tissue1.01492015
84MP0000778_abnormal_nervous_system1.00450433
85MP0005394_taste/olfaction_phenotype0.99950199
86MP0005499_abnormal_olfactory_system0.99950199
87MP0002114_abnormal_axial_skeleton0.99836925
88MP0003718_maternal_effect0.99780119
89MP0003121_genomic_imprinting0.99375355
90MP0000579_abnormal_nail_morphology0.98923714
91MP0000467_abnormal_esophagus_morphology0.98289423
92MP0002751_abnormal_autonomic_nervous0.98087234
93MP0002177_abnormal_outer_ear0.95950919
94MP0003984_embryonic_growth_retardation0.95635789
95MP0005409_darkened_coat_color0.95574965
96MP0001299_abnormal_eye_distance/0.95266676
97MP0000013_abnormal_adipose_tissue0.95205229
98MP0002088_abnormal_embryonic_growth/wei0.94302741
99MP0001915_intracranial_hemorrhage0.94086951
100MP0003077_abnormal_cell_cycle0.94072783
101MP0002932_abnormal_joint_morphology0.92753661
102MP0002080_prenatal_lethality0.91990507
103MP0003115_abnormal_respiratory_system0.91098078
104MP0004084_abnormal_cardiac_muscle0.90972265
105MP0003938_abnormal_ear_development0.90094164
106MP0003935_abnormal_craniofacial_develop0.90031188
107MP0000678_abnormal_parathyroid_gland0.89191607
108MP0000767_abnormal_smooth_muscle0.89103178
109MP0000003_abnormal_adipose_tissue0.87981380
110MP0001529_abnormal_vocalization0.87930403
111MP0000537_abnormal_urethra_morphology0.87675956
112MP0003122_maternal_imprinting0.87341329
113MP0001672_abnormal_embryogenesis/_devel0.86666304
114MP0005380_embryogenesis_phenotype0.86666304
115MP0003942_abnormal_urinary_system0.86662557
116MP0002060_abnormal_skin_morphology0.86639543
117MP0000049_abnormal_middle_ear0.85941148
118MP0009053_abnormal_anal_canal0.85746615
119MP0001545_abnormal_hematopoietic_system0.84279357
120MP0005397_hematopoietic_system_phenotyp0.84279357
121MP0010630_abnormal_cardiac_muscle0.84154688
122MP0002160_abnormal_reproductive_system0.84153875
123MP0000534_abnormal_ureter_morphology0.83853063
124MP0002933_joint_inflammation0.81244736
125MP0008770_decreased_survivor_rate0.81183397
126MP0005501_abnormal_skin_physiology0.80714020
127MP0003045_fibrosis0.80481219
128MP0001346_abnormal_lacrimal_gland0.79975916
129MP0000465_gastrointestinal_hemorrhage0.79889203
130MP0002109_abnormal_limb_morphology0.78933960
131MP0001340_abnormal_eyelid_morphology0.78874673
132MP0001614_abnormal_blood_vessel0.77587841
133MP0000266_abnormal_heart_morphology0.76378503
134MP0005391_vision/eye_phenotype0.76104604
135MP0005193_abnormal_anterior_eye0.75400185
136MP0002081_perinatal_lethality0.75125249
137MP0002128_abnormal_blood_circulation0.75002420
138MP0003567_abnormal_fetal_cardiomyocyte0.74095260
139MP0004134_abnormal_chest_morphology0.74088257
140MP0000685_abnormal_immune_system0.69269273
141MP0002249_abnormal_larynx_morphology0.68789284
142MP0002113_abnormal_skeleton_development0.67713158
143MP0009703_decreased_birth_body0.67560662
144MP0008057_abnormal_DNA_replication0.66947314
145MP0004087_abnormal_muscle_fiber0.66595265
146MP0003111_abnormal_nucleus_morphology0.66447228
147MP0000703_abnormal_thymus_morphology0.65346114
148MP0000490_abnormal_crypts_of0.64618227
149MP0002116_abnormal_craniofacial_bone0.64533116

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.58467634
2Premature rupture of membranes (HP:0001788)4.18409742
3Shallow orbits (HP:0000586)4.00506471
4Cerebral aneurysm (HP:0004944)3.63965307
5Ankle contracture (HP:0006466)3.53781233
6Genu recurvatum (HP:0002816)3.06826132
7Bowel diverticulosis (HP:0005222)3.05502240
8Bladder diverticulum (HP:0000015)3.05299622
9Cervical subluxation (HP:0003308)2.96627865
10Short 4th metacarpal (HP:0010044)2.81326754
11Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.81326754
12Dilatation of the ascending aorta (HP:0005111)2.74313353
13Aortic dissection (HP:0002647)2.72597416
14Hyperacusis (HP:0010780)2.71901741
15Renal duplication (HP:0000075)2.67402144
16Coronal craniosynostosis (HP:0004440)2.67096250
17High anterior hairline (HP:0009890)2.63670474
18Increased density of long bones (HP:0006392)2.62402469
19Mitral valve prolapse (HP:0001634)2.59877615
20Thin bony cortex (HP:0002753)2.58786463
21Peritonitis (HP:0002586)2.57971819
22Buphthalmos (HP:0000557)2.44268409
23Hypoplastic pelvis (HP:0008839)2.43372299
24Broad metatarsal (HP:0001783)2.36789652
25Aortic aneurysm (HP:0004942)2.35772776
26Atrophic scars (HP:0001075)2.33342046
27Upper limb amyotrophy (HP:0009129)2.31900155
28Distal upper limb amyotrophy (HP:0007149)2.31900155
29High pitched voice (HP:0001620)2.28151259
30Missing ribs (HP:0000921)2.26070149
31Abnormality of the calcaneus (HP:0008364)2.25847986
32Broad distal phalanx of finger (HP:0009836)2.23063180
33Macroorchidism (HP:0000053)2.20919267
34Chromosomal breakage induced by crosslinking agents (HP:0003221)2.19762982
35Morphological abnormality of the middle ear (HP:0008609)2.17932320
36Deviation of the hallux (HP:0010051)2.16283343
37Hallux valgus (HP:0001822)2.15224937
38Neonatal short-limb short stature (HP:0008921)2.14714688
39Soft skin (HP:0000977)2.12971304
40Abnormality of the 4th metacarpal (HP:0010012)2.12395804
41Cortical dysplasia (HP:0002539)2.11120260
42Abnormality of oral frenula (HP:0000190)2.06988752
43Abnormality of the astrocytes (HP:0100707)2.04795655
44Astrocytoma (HP:0009592)2.04795655
45Blue sclerae (HP:0000592)2.04307301
46Chromsome breakage (HP:0040012)2.03042342
47Wrist flexion contracture (HP:0001239)2.02738784
48Pointed chin (HP:0000307)2.02101047
49Ankyloglossia (HP:0010296)2.02032645
50Skull defect (HP:0001362)2.00563089
51Wormian bones (HP:0002645)2.00253316
52Abnormality of the peritoneum (HP:0002585)2.00103173
53Flat cornea (HP:0007720)1.98053701
54Biconcave vertebral bodies (HP:0004586)1.97762208
55Breech presentation (HP:0001623)1.97536532
56Capillary hemangiomas (HP:0005306)1.97436154
57Fragile skin (HP:0001030)1.97210801
58Fibroma (HP:0010614)1.96934639
59Fibrous tissue neoplasm (HP:0012316)1.96448167
60Mitral regurgitation (HP:0001653)1.95988539
61Spinal cord lesions (HP:0100561)1.95383687
62Syringomyelia (HP:0003396)1.95383687
63Increased nuchal translucency (HP:0010880)1.93577739
64Abnormality of abdominal situs (HP:0011620)1.92964579
65Abdominal situs inversus (HP:0003363)1.92964579
66Wide anterior fontanel (HP:0000260)1.92857438
67Broad palm (HP:0001169)1.92690444
68Aplasia/Hypoplasia of the sacrum (HP:0008517)1.92463723
69Asymmetry of the thorax (HP:0001555)1.92343884
70Microglossia (HP:0000171)1.91721613
71Increased connective tissue (HP:0009025)1.91385995
72Broad phalanges of the hand (HP:0009768)1.90730303
73Hand muscle atrophy (HP:0009130)1.89523209
74Reticulocytopenia (HP:0001896)1.88588607
75Broad thumb (HP:0011304)1.87752045
76Abnormal umbilical cord blood vessels (HP:0011403)1.87517215
77Single umbilical artery (HP:0001195)1.87517215
78Abnormality of the fetal cardiovascular system (HP:0010948)1.87517215
79Septo-optic dysplasia (HP:0100842)1.85053522
80Aneurysm (HP:0002617)1.84869974
81Broad phalanx (HP:0006009)1.84630731
82Broad finger (HP:0001500)1.83764267
83Slender build (HP:0001533)1.83569014
84Ependymoma (HP:0002888)1.83218555
85Overriding aorta (HP:0002623)1.82460346
86Abnormality of the phalanges of the hallux (HP:0010057)1.82089550
87Deviation of the thumb (HP:0009603)1.81076973
88Cutaneous melanoma (HP:0012056)1.80272180
89Facial hemangioma (HP:0000329)1.80237881
90Selective tooth agenesis (HP:0001592)1.80166927
91Congenital glaucoma (HP:0001087)1.80162556
92Ulnar bowing (HP:0003031)1.78875246
93Abnormality of dentin (HP:0010299)1.78784036
94Abnormal lung lobation (HP:0002101)1.77865434
95Lymphangioma (HP:0100764)1.77296039
96Insomnia (HP:0100785)1.76960044
97Lower limb amyotrophy (HP:0007210)1.76512732
98Trigonocephaly (HP:0000243)1.76498177
99Thrombocytosis (HP:0001894)1.75911468
100Meckel diverticulum (HP:0002245)1.75661419
101Broad face (HP:0000283)1.75410675
102Achilles tendon contracture (HP:0001771)1.75032975
103Radial bowing (HP:0002986)1.74876221
104Annular pancreas (HP:0001734)1.74546356
105Enlarged penis (HP:0000040)1.74105994
106Vascular tortuosity (HP:0004948)1.73589220
107Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.73201402
108Camptodactyly of toe (HP:0001836)1.72697818
109Cutaneous syndactyly (HP:0012725)1.72354127
110Distal lower limb amyotrophy (HP:0008944)1.72247532
111Slender long bone (HP:0003100)1.72178588
112Bifid tongue (HP:0010297)1.71569336
113Abnormal number of incisors (HP:0011064)1.71322566
114Cutaneous finger syndactyly (HP:0010554)1.70879784
115Spinal rigidity (HP:0003306)1.70698753
116Facial cleft (HP:0002006)1.69680114
117Proximal placement of thumb (HP:0009623)1.69342646
118Congenital hip dislocation (HP:0001374)1.69158392
119Aplasia/Hypoplasia of the uvula (HP:0010293)1.68774224
120Hematochezia (HP:0002573)1.68354662
121Humeroradial synostosis (HP:0003041)1.68217184
122Synostosis involving the elbow (HP:0003938)1.68217184
123Broad long bones (HP:0005622)1.68202298
124Persistence of primary teeth (HP:0006335)1.67898312
125Long eyelashes (HP:0000527)1.67111574
126Mesomelia (HP:0003027)1.67096790
127Polygenic inheritance (HP:0010982)1.66977151
128Elfin facies (HP:0004428)1.65178607
129Rib fusion (HP:0000902)1.65163352
130Midline defect of the nose (HP:0004122)1.64815928
131Apathy (HP:0000741)1.64670648
132Abnormal number of erythroid precursors (HP:0012131)1.64571789
133Absent epiphyses (HP:0010577)1.63891569
134Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.63891569
135Hemivertebrae (HP:0002937)1.63768742
136Papilledema (HP:0001085)1.63620834
137Disproportionate tall stature (HP:0001519)1.63318608
138Increased variability in muscle fiber diameter (HP:0003557)1.63178517
139Abnormality of the acetabulum (HP:0003170)1.63029306
140Lower limb asymmetry (HP:0100559)1.62981272
141Diminished motivation (HP:0000745)1.62454568
142Bilateral microphthalmos (HP:0007633)1.61696999
143Bowing of the arm (HP:0006488)1.61434934
144Bowed forearm bones (HP:0003956)1.61434934
145Short nail (HP:0001799)1.61162300
146Duplication of thumb phalanx (HP:0009942)1.61114316
147Abnormality of the diencephalon (HP:0010662)1.60861411
148Abnormality of the ileum (HP:0001549)1.60493104
149Fibular hypoplasia (HP:0003038)1.60453524
150Arterial tortuosity (HP:0005116)1.60422906
151Delayed cranial suture closure (HP:0000270)1.60111214
152Aplasia/Hypoplasia of the fibula (HP:0006492)1.58953770
153Short 5th finger (HP:0009237)1.57952713
154Cellulitis (HP:0100658)1.57611927
155Joint laxity (HP:0001388)1.57597546
156Hypoplasia of the capital femoral epiphysis (HP:0003090)1.56682534
157Adducted thumb (HP:0001181)1.56522854
158Abnormality of cells of the erythroid lineage (HP:0012130)1.56316926
159Premature skin wrinkling (HP:0100678)1.55920238
160Broad ribs (HP:0000885)1.55744637
161Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.53907937
162Abnormality of skeletal muscle fiber size (HP:0012084)1.53790355

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PKN24.56175995
2TRIB34.20862480
3EEF2K3.75014872
4VRK23.69681440
5MAP3K102.70459113
6PDGFRA2.63720795
7TTN2.52568141
8SCYL22.48140109
9BUB12.45378300
10FLT32.40586974
11WEE12.38477529
12SRPK12.37475235
13DDR22.23297136
14ALK2.15399525
15CDK122.15246196
16TTK2.08908590
17LRRK21.87682949
18CHEK21.86809727
19TIE11.82709769
20CDC71.81895188
21RIPK11.77550706
22PAK21.68188879
23SMG11.61602734
24MAP4K11.59892818
25CDK71.56802504
26LATS11.56274550
27PLK41.52602261
28CSF1R1.50211688
29BCKDK1.48770285
30STK101.42838183
31CDK81.39298629
32AURKA1.38731606
33PNCK1.38369223
34DYRK31.34827448
35DYRK21.33005505
36ATR1.32684209
37CSNK1G31.32338800
38PRKD31.31391548
39PTK61.29846347
40PLK11.29610903
41NEK91.29350602
42TGFBR11.28362090
43ERN11.28037347
44VRK11.24343895
45CSNK1G11.22556920
46CDK191.20601120
47LATS21.20497089
48SIK21.19266999
49BMX1.19124571
50TYRO31.18332731
51SIK11.16719811
52PAK41.16107908
53CSNK1A1L1.16078057
54EPHB21.13006408
55NEK11.12701452
56AURKB1.12533370
57MAP2K71.10917054
58MTOR1.10818693
59RET1.09863713
60TESK11.09798734
61CAMKK11.09277879
62KIT1.08722416
63TESK21.08292633
64FGFR11.07282203
65TSSK61.06153679
66TAF11.05001532
67CSNK1G21.04127150
68MAP3K81.01646795
69PLK31.00639795
70ICK1.00423107
71FGFR20.99223569
72KSR20.98871697
73RPS6KA40.98673160
74PASK0.98568008
75FGFR30.98443178
76PDGFRB0.98430257
77EIF2AK10.97508923
78NME20.96908597
79EPHB10.95018902
80NTRK10.93971218
81ZAP700.93746302
82LIMK10.90741818
83PBK0.90544309
84PAK60.89975183
85CLK10.81715770
86PRKCH0.81657025
87NEK20.80804381
88BCR0.80765662
89NUAK10.80619921
90STK160.77987709
91CDK60.76722358
92MAP3K70.74573795
93ERBB40.73635755
94HIPK20.73445178
95HCK0.71579213
96JAK30.70410984
97CDK40.67607413
98ILK0.66896403
99WNK10.66592862
100GRK60.66403599
101MKNK10.65568104
102ZAK0.64190381
103BRSK10.62535753
104CDK10.61292372
105MAP3K20.60992213
106KSR10.60800437
107PRKD10.59491940
108UHMK10.59277293
109ATM0.58781623
110CCNB10.58781365
111KDR0.58456592
112RPS6KB20.55048346
113PIM20.54612760
114MOS0.54287307
115FES0.52637693
116CDK150.51445136
117TRPM70.50927288
118PTK20.49999423
119TGFBR20.49903549
120MAP3K40.49761191
121MARK20.48221372
122MAPKAPK50.47876960
123FRK0.46239341
124NTRK20.44746820
125FGFR40.44433312
126CDK20.44203019
127CDK11A0.43654068
128CDK180.43400974
129MET0.43307576
130AKT20.42647156
131RPS6KA20.42088286
132CDK140.41857263
133BRSK20.41527612
134EPHA20.40912521
135ITK0.39831519
136CAMK1G0.39498208
137RPS6KC10.38991773
138RPS6KL10.38991773
139ROCK20.38977273
140CAMK40.38788596
141PAK10.38526107
142TRIM280.38479686
143CSNK2A10.37956137
144STK40.37950060
145SRC0.37923820
146JAK10.36827795
147PRKG20.36811764
148MAPK10.36644052
149CHEK10.36311783
150BTK0.35945938
151PAK30.35630578
152CDK90.35411686
153RPS6KA60.35311880
154EGFR0.35248593
155MAP3K90.34175687
156RPS6KA10.33512286
157LCK0.33065697

Predicted pathways (KEGG)

RankGene SetZ-score
1Base excision repair_Homo sapiens_hsa034102.77569447
2Nucleotide excision repair_Homo sapiens_hsa034202.24811900
3Ribosome_Homo sapiens_hsa030101.98231501
4Homologous recombination_Homo sapiens_hsa034401.96787271
5Fanconi anemia pathway_Homo sapiens_hsa034601.95720207
6Chronic myeloid leukemia_Homo sapiens_hsa052201.76493962
7Focal adhesion_Homo sapiens_hsa045101.66880222
8Pyrimidine metabolism_Homo sapiens_hsa002401.63309482
9Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.62173321
10RNA polymerase_Homo sapiens_hsa030201.62043952
11Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.59227877
12Biosynthesis of amino acids_Homo sapiens_hsa012301.57225622
13Proteoglycans in cancer_Homo sapiens_hsa052051.56907843
14Non-homologous end-joining_Homo sapiens_hsa034501.56147172
15ECM-receptor interaction_Homo sapiens_hsa045121.53235940
16AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.52816924
17Glioma_Homo sapiens_hsa052141.47604419
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.46525777
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.42675132
20mTOR signaling pathway_Homo sapiens_hsa041501.38826384
21Basal transcription factors_Homo sapiens_hsa030221.37204315
22Colorectal cancer_Homo sapiens_hsa052101.34854196
23Neurotrophin signaling pathway_Homo sapiens_hsa047221.34158333
24MicroRNAs in cancer_Homo sapiens_hsa052061.33352804
25Small cell lung cancer_Homo sapiens_hsa052221.32893105
26Fatty acid elongation_Homo sapiens_hsa000621.30802938
27Central carbon metabolism in cancer_Homo sapiens_hsa052301.29468357
28Amoebiasis_Homo sapiens_hsa051461.29195229
29Adherens junction_Homo sapiens_hsa045201.28486172
30DNA replication_Homo sapiens_hsa030301.27106544
31Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.26113476
32Axon guidance_Homo sapiens_hsa043601.25375731
33Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.24941132
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.24070843
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23371606
36Non-small cell lung cancer_Homo sapiens_hsa052231.21011346
37Sulfur relay system_Homo sapiens_hsa041221.20795920
38Steroid biosynthesis_Homo sapiens_hsa001001.20484983
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.20483476
40VEGF signaling pathway_Homo sapiens_hsa043701.19635779
41Protein export_Homo sapiens_hsa030601.19503157
42B cell receptor signaling pathway_Homo sapiens_hsa046621.19408373
43HTLV-I infection_Homo sapiens_hsa051661.18387680
44Platelet activation_Homo sapiens_hsa046111.17533945
45Viral myocarditis_Homo sapiens_hsa054161.15854825
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.15548157
47mRNA surveillance pathway_Homo sapiens_hsa030151.14916757
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.14802050
49Leukocyte transendothelial migration_Homo sapiens_hsa046701.13181334
50Cell cycle_Homo sapiens_hsa041101.12969929
51Mismatch repair_Homo sapiens_hsa034301.11588142
52Bladder cancer_Homo sapiens_hsa052191.11574867
53Pentose phosphate pathway_Homo sapiens_hsa000301.11269759
54Proteasome_Homo sapiens_hsa030501.10317387
55Estrogen signaling pathway_Homo sapiens_hsa049151.09742558
56Hippo signaling pathway_Homo sapiens_hsa043901.08984141
57Thyroid cancer_Homo sapiens_hsa052161.07631712
58Viral carcinogenesis_Homo sapiens_hsa052031.05605390
59Lysine degradation_Homo sapiens_hsa003101.05077284
60Gap junction_Homo sapiens_hsa045401.04838012
61Pancreatic cancer_Homo sapiens_hsa052121.04693010
62N-Glycan biosynthesis_Homo sapiens_hsa005101.04229404
63Selenocompound metabolism_Homo sapiens_hsa004501.03135505
64Renal cell carcinoma_Homo sapiens_hsa052111.02159116
65Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.01489555
66Carbon metabolism_Homo sapiens_hsa012001.01155924
67Thyroid hormone signaling pathway_Homo sapiens_hsa049191.00838422
68Endometrial cancer_Homo sapiens_hsa052130.99230062
69Toxoplasmosis_Homo sapiens_hsa051450.98061329
70Osteoclast differentiation_Homo sapiens_hsa043800.97980272
71Acute myeloid leukemia_Homo sapiens_hsa052210.97762179
72Long-term potentiation_Homo sapiens_hsa047200.97437265
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97065792
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96831009
75HIF-1 signaling pathway_Homo sapiens_hsa040660.96545317
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96464951
77Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.95890868
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.95848885
79Notch signaling pathway_Homo sapiens_hsa043300.95116842
80Regulation of actin cytoskeleton_Homo sapiens_hsa048100.94679175
81Dilated cardiomyopathy_Homo sapiens_hsa054140.94339502
82Antigen processing and presentation_Homo sapiens_hsa046120.94313488
83TGF-beta signaling pathway_Homo sapiens_hsa043500.94093362
84Shigellosis_Homo sapiens_hsa051310.92628721
85Rap1 signaling pathway_Homo sapiens_hsa040150.91141367
86Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.90445122
87Pathways in cancer_Homo sapiens_hsa052000.90420966
88RNA transport_Homo sapiens_hsa030130.89455457
89Leishmaniasis_Homo sapiens_hsa051400.89154131
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.87778526
91Purine metabolism_Homo sapiens_hsa002300.87042313
92Wnt signaling pathway_Homo sapiens_hsa043100.85977704
93Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.85966181
94GnRH signaling pathway_Homo sapiens_hsa049120.85719865
95Endocytosis_Homo sapiens_hsa041440.84521740
96Basal cell carcinoma_Homo sapiens_hsa052170.83796723
97Huntingtons disease_Homo sapiens_hsa050160.83717091
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.82191606
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.79143886
100PI3K-Akt signaling pathway_Homo sapiens_hsa041510.77912219
101Hepatitis B_Homo sapiens_hsa051610.77906944
102One carbon pool by folate_Homo sapiens_hsa006700.77676877
103Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77011239
104Parkinsons disease_Homo sapiens_hsa050120.76327387
105Melanogenesis_Homo sapiens_hsa049160.75431796
106T cell receptor signaling pathway_Homo sapiens_hsa046600.75221719
107Oocyte meiosis_Homo sapiens_hsa041140.75031332
108Cocaine addiction_Homo sapiens_hsa050300.74756183
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.74752846
110Spliceosome_Homo sapiens_hsa030400.74106579
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.73294091
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73069305
113MAPK signaling pathway_Homo sapiens_hsa040100.72603997
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72278641
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.71542744
116Melanoma_Homo sapiens_hsa052180.70754828
117Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.69886958
118Folate biosynthesis_Homo sapiens_hsa007900.69650680
119Pyruvate metabolism_Homo sapiens_hsa006200.69390450
120RNA degradation_Homo sapiens_hsa030180.69382775
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.68540881
122TNF signaling pathway_Homo sapiens_hsa046680.67561691
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.66387718
124Alcoholism_Homo sapiens_hsa050340.65559278
125Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65295544
126Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.65229981
127p53 signaling pathway_Homo sapiens_hsa041150.65180784
128Hedgehog signaling pathway_Homo sapiens_hsa043400.64454971
129Glycosaminoglycan degradation_Homo sapiens_hsa005310.63857985
130Oxytocin signaling pathway_Homo sapiens_hsa049210.63802197
131Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63539541
132Insulin resistance_Homo sapiens_hsa049310.63076067
133Gastric acid secretion_Homo sapiens_hsa049710.62718961
134Dopaminergic synapse_Homo sapiens_hsa047280.62197534
135Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61573823
136Cholinergic synapse_Homo sapiens_hsa047250.60821428
137Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60060349
138Glutathione metabolism_Homo sapiens_hsa004800.59828380
139Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59487416
140Prostate cancer_Homo sapiens_hsa052150.59366244
141Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.58988939
142Galactose metabolism_Homo sapiens_hsa000520.58233014
143Fatty acid metabolism_Homo sapiens_hsa012120.55621886
144Protein digestion and absorption_Homo sapiens_hsa049740.52652780
145Fructose and mannose metabolism_Homo sapiens_hsa000510.52062824
146Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47129321
147Oxidative phosphorylation_Homo sapiens_hsa001900.42108128
148Tight junction_Homo sapiens_hsa045300.39643017
149Metabolic pathways_Homo sapiens_hsa011000.39357849
150AMPK signaling pathway_Homo sapiens_hsa041520.32799146

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