XYLB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.56032847
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.56032847
3L-phenylalanine metabolic process (GO:0006558)7.33729739
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.33729739
5aromatic amino acid family catabolic process (GO:0009074)6.96837597
6indole-containing compound catabolic process (GO:0042436)6.45755877
7indolalkylamine catabolic process (GO:0046218)6.45755877
8tryptophan catabolic process (GO:0006569)6.45755877
9glyoxylate metabolic process (GO:0046487)6.34791614
10kynurenine metabolic process (GO:0070189)6.09238006
11tryptophan metabolic process (GO:0006568)6.06645489
12cysteine metabolic process (GO:0006534)6.03190800
13serine family amino acid catabolic process (GO:0009071)5.70252261
14lysine catabolic process (GO:0006554)5.68605673
15lysine metabolic process (GO:0006553)5.68605673
16sulfur amino acid catabolic process (GO:0000098)5.67384737
17bile acid biosynthetic process (GO:0006699)5.60171845
18triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.39325124
19urea cycle (GO:0000050)5.21468813
20urea metabolic process (GO:0019627)5.21468813
21urate metabolic process (GO:0046415)5.20350888
22homocysteine metabolic process (GO:0050667)5.20299706
23alpha-linolenic acid metabolic process (GO:0036109)5.15257959
24fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.13131649
25aromatic amino acid family metabolic process (GO:0009072)5.12606921
26cellular modified amino acid catabolic process (GO:0042219)4.99201941
27drug transmembrane transport (GO:0006855)4.92393163
28amino-acid betaine metabolic process (GO:0006577)4.91043237
29drug catabolic process (GO:0042737)4.88916492
30alpha-amino acid catabolic process (GO:1901606)4.85265014
31negative regulation of fibrinolysis (GO:0051918)4.83787971
32coenzyme catabolic process (GO:0009109)4.83199375
33nitrogen cycle metabolic process (GO:0071941)4.80926571
34serine family amino acid metabolic process (GO:0009069)4.80655614
35bile acid metabolic process (GO:0008206)4.75048346
36protein carboxylation (GO:0018214)4.71020548
37peptidyl-glutamic acid carboxylation (GO:0017187)4.71020548
38glycine metabolic process (GO:0006544)4.66605736
39high-density lipoprotein particle remodeling (GO:0034375)4.66213430
40regulation of fibrinolysis (GO:0051917)4.61928415
41regulation of protein activation cascade (GO:2000257)4.61772601
42cellular amino acid catabolic process (GO:0009063)4.60425663
43complement activation, alternative pathway (GO:0006957)4.58263982
44tyrosine metabolic process (GO:0006570)4.55703252
45cellular ketone body metabolic process (GO:0046950)4.53596663
46indolalkylamine metabolic process (GO:0006586)4.52726915
47serine family amino acid biosynthetic process (GO:0009070)4.48857204
48glutamate metabolic process (GO:0006536)4.40772325
49exogenous drug catabolic process (GO:0042738)4.40003949
50cellular biogenic amine catabolic process (GO:0042402)4.39848183
51amine catabolic process (GO:0009310)4.39848183
52blood coagulation, intrinsic pathway (GO:0007597)4.37445715
53regulation of complement activation (GO:0030449)4.31590945
54very-low-density lipoprotein particle assembly (GO:0034379)4.31029046
55negative regulation of cholesterol transport (GO:0032375)4.28916893
56negative regulation of sterol transport (GO:0032372)4.28916893
57oxidative demethylation (GO:0070989)4.24916794
58benzene-containing compound metabolic process (GO:0042537)4.22524242
59omega-hydroxylase P450 pathway (GO:0097267)4.17737825
60short-chain fatty acid metabolic process (GO:0046459)4.17031724
61triglyceride homeostasis (GO:0070328)4.16951042
62acylglycerol homeostasis (GO:0055090)4.16951042
63cellular glucuronidation (GO:0052695)4.15840562
64drug transport (GO:0015893)4.14270047
65cholesterol efflux (GO:0033344)4.14117937
66regulation of triglyceride catabolic process (GO:0010896)4.11366755
67regulation of cholesterol esterification (GO:0010872)4.06508115
68aspartate family amino acid catabolic process (GO:0009068)4.03747315
69intestinal cholesterol absorption (GO:0030299)4.02904131
70reverse cholesterol transport (GO:0043691)4.02267227
71ethanol oxidation (GO:0006069)4.00459989
72bile acid and bile salt transport (GO:0015721)3.99496923
73phenylpropanoid metabolic process (GO:0009698)3.98194050
74carboxylic acid catabolic process (GO:0046395)3.97135979
75organic acid catabolic process (GO:0016054)3.97135979
76acetyl-CoA metabolic process (GO:0006084)3.96061484
77protein-lipid complex remodeling (GO:0034368)3.95748924
78macromolecular complex remodeling (GO:0034367)3.95748924
79plasma lipoprotein particle remodeling (GO:0034369)3.95748924
80imidazole-containing compound metabolic process (GO:0052803)3.95705897
81drug metabolic process (GO:0017144)3.92990099
82aldehyde catabolic process (GO:0046185)3.92140902
83dicarboxylic acid biosynthetic process (GO:0043650)3.91958785
84ketone body metabolic process (GO:1902224)3.90982691
85regulation of plasminogen activation (GO:0010755)3.90537487
86plasma lipoprotein particle assembly (GO:0034377)3.89610101
87regulation of cholesterol homeostasis (GO:2000188)3.85542766
882-oxoglutarate metabolic process (GO:0006103)3.82278624
89arginine metabolic process (GO:0006525)3.79337677
90cofactor catabolic process (GO:0051187)3.78201600
91uronic acid metabolic process (GO:0006063)3.77216498
92glucuronate metabolic process (GO:0019585)3.77216498
93regulation of bile acid biosynthetic process (GO:0070857)3.75014749
94phospholipid efflux (GO:0033700)3.72371474
95heme transport (GO:0015886)3.72192254
96flavonoid metabolic process (GO:0009812)3.72177328
97epoxygenase P450 pathway (GO:0019373)3.71805625
98valine metabolic process (GO:0006573)3.67689515
99plasma lipoprotein particle clearance (GO:0034381)3.67079081
100negative regulation of protein activation cascade (GO:2000258)3.64435718
101carnitine metabolic process (GO:0009437)3.64245000
102fatty acid beta-oxidation (GO:0006635)3.61505789
103fatty acid oxidation (GO:0019395)3.59747418
104response to mercury ion (GO:0046689)3.58505419
105S-adenosylmethionine metabolic process (GO:0046500)3.54978748
106monocarboxylic acid catabolic process (GO:0072329)3.52506911
107lipid oxidation (GO:0034440)3.52362105
108peptidyl-glutamic acid modification (GO:0018200)3.50770998
109fibrinolysis (GO:0042730)3.47145873
110branched-chain amino acid catabolic process (GO:0009083)3.44065242
111cholesterol homeostasis (GO:0042632)3.42607450
112plasma lipoprotein particle organization (GO:0071827)3.41557058
113negative regulation of lipase activity (GO:0060192)3.41342499
114fatty acid catabolic process (GO:0009062)3.41287413
115alkaloid metabolic process (GO:0009820)3.24666026
116negative regulation of hemostasis (GO:1900047)3.22803518
117negative regulation of blood coagulation (GO:0030195)3.22803518
118low-density lipoprotein particle remodeling (GO:0034374)3.20754313
119proline metabolic process (GO:0006560)3.20681341
120protein-lipid complex assembly (GO:0065005)3.14920442
121L-methionine salvage (GO:0071267)3.14882650
122L-methionine biosynthetic process (GO:0071265)3.14882650
123amino acid salvage (GO:0043102)3.14882650
124L-serine metabolic process (GO:0006563)3.07955682
125protein-lipid complex subunit organization (GO:0071825)3.03729550
126water-soluble vitamin biosynthetic process (GO:0042364)3.03621110
127negative regulation of coagulation (GO:0050819)3.02785485
128tetrahydrofolate metabolic process (GO:0046653)3.01753895
129arginine catabolic process (GO:0006527)3.00694374
130negative regulation of complement activation (GO:0045916)2.99393905
131biotin metabolic process (GO:0006768)2.94720642
132positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.92158183
133glutamine family amino acid catabolic process (GO:0009065)2.89514658
134negative regulation of wound healing (GO:0061045)2.83584797
135protein activation cascade (GO:0072376)2.81347668

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.25107113
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.15322766
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.39965489
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.28520387
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.99807557
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.83839647
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.65339068
8E2F7_22180533_ChIP-Seq_HELA_Human4.10732067
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.97699502
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.90878798
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.18698002
12ZNF274_21170338_ChIP-Seq_K562_Hela2.66798477
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.26629234
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.23434047
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.21939980
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16161152
17TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.13096562
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.04941881
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.4477828
20TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.93865369
21ETS1_20019798_ChIP-Seq_JURKAT_Human1.92137949
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91413574
23VDR_22108803_ChIP-Seq_LS180_Human1.81736531
24PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77914241
25* SRF_21415370_ChIP-Seq_HL-1_Mouse1.77262519
26E2F4_17652178_ChIP-ChIP_JURKAT_Human1.73260343
27ELK1_19687146_ChIP-ChIP_HELA_Human1.69543652
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.69125440
29ER_23166858_ChIP-Seq_MCF-7_Human1.66045556
30CREB1_15753290_ChIP-ChIP_HEK293T_Human1.64715173
31FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.62775879
32* HNF4A_19822575_ChIP-Seq_HepG2_Human1.54291328
33FOXA2_19822575_ChIP-Seq_HepG2_Human1.50020654
34CLOCK_20551151_ChIP-Seq_293T_Human1.49822759
35PADI4_21655091_ChIP-ChIP_MCF-7_Human1.46093493
36SALL1_21062744_ChIP-ChIP_HESCs_Human1.45991279
37POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44810207
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.40078196
39NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.39274726
40PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.36728874
41NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.35420810
42* MYC_18555785_ChIP-Seq_MESCs_Mouse1.34227423
43RXRA_24833708_ChIP-Seq_LIVER_Mouse1.32523320
44STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.32409941
45MYC_18940864_ChIP-ChIP_HL60_Human1.31809805
46IGF1R_20145208_ChIP-Seq_DFB_Human1.31474857
47GABP_19822575_ChIP-Seq_HepG2_Human1.30824309
48STAT3_1855785_ChIP-Seq_MESCs_Mouse1.30064904
49GBX2_23144817_ChIP-Seq_PC3_Human1.29547432
50ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.29120049
51KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.28161019
52EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.27005808
53* E2F1_21310950_ChIP-Seq_MCF-7_Human1.25938671
54VDR_23849224_ChIP-Seq_CD4+_Human1.24085962
55PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.22321668
56KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.18196748
57KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.18196748
58KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.18196748
59YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16814069
60TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16645305
61NFE2_27457419_Chip-Seq_LIVER_Mouse1.16280706
62ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.16266837
63* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.15089163
64FOXP3_21729870_ChIP-Seq_TREG_Human1.13721521
65DCP1A_22483619_ChIP-Seq_HELA_Human1.11654878
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.10659699
67KDM5A_27292631_Chip-Seq_BREAST_Human1.10643478
68CTBP1_25329375_ChIP-Seq_LNCAP_Human1.10363229
69CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.10035701
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.08957984
71SOX2_27498859_Chip-Seq_STOMACH_Mouse1.08448389
72AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08391339
73MYC_18358816_ChIP-ChIP_MESCs_Mouse1.07009670
74FOXM1_23109430_ChIP-Seq_U2OS_Human1.06707591
75EZH2_27294783_Chip-Seq_NPCs_Mouse1.06453547
76YY1_21170310_ChIP-Seq_MESCs_Mouse1.05224300
77SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05209162
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.04869878
79CBP_20019798_ChIP-Seq_JUKART_Human1.04491543
80IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04491543
81EWS_26573619_Chip-Seq_HEK293_Human1.04476816
82* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04430751
83ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04423259
84GATA4_25053715_ChIP-Seq_YYC3_Human1.03526108
85FUS_26573619_Chip-Seq_HEK293_Human1.03481491
86TTF2_22483619_ChIP-Seq_HELA_Human1.03077908
87ESR2_21235772_ChIP-Seq_MCF-7_Human1.02232311
88NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.01378165
89MYC_19030024_ChIP-ChIP_MESCs_Mouse1.00707570
90ESR1_15608294_ChIP-ChIP_MCF-7_Human1.00475671
91CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99490275
92HTT_18923047_ChIP-ChIP_STHdh_Human0.99121045
93TAF15_26573619_Chip-Seq_HEK293_Human0.98563124
94HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.97441092
95CDX2_20551321_ChIP-Seq_CACO-2_Human0.97371720
96FLI1_27457419_Chip-Seq_LIVER_Mouse0.96760189
97THAP11_20581084_ChIP-Seq_MESCs_Mouse0.96446313
98ESR1_21235772_ChIP-Seq_MCF-7_Human0.94495032
99GATA1_22025678_ChIP-Seq_K562_Human0.94088147
100RARG_19884340_ChIP-ChIP_MEFs_Mouse0.93438099
101PHF8_20622853_ChIP-Seq_HELA_Human0.92230833
102PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90417777
103KAP1_22055183_ChIP-Seq_ESCs_Mouse0.90287531
104ETV1_20927104_ChIP-Seq_GIST48_Human0.88900213
105CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.88075297
106BCAT_22108803_ChIP-Seq_LS180_Human0.87703261
107STAT3_23295773_ChIP-Seq_U87_Human0.87164458
108MYCN_18555785_ChIP-Seq_MESCs_Mouse0.87122653
109SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.86571349
110NANOG_19829295_ChIP-Seq_ESCs_Human0.86562847
111SOX2_19829295_ChIP-Seq_ESCs_Human0.86562847
112AR_21909140_ChIP-Seq_LNCAP_Human0.86095502
113STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.86010917
114RBPJ_21746931_ChIP-Seq_IB4_Human0.85972676
115HNFA_21074721_ChIP-Seq_CACO-2_Human0.85730767
116* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.85465655
117FOXA1_27270436_Chip-Seq_PROSTATE_Human0.84775090
118TCF3_18692474_ChIP-Seq_MEFs_Mouse0.82610919
119RARA_24833708_ChIP-Seq_LIVER_Mouse0.82598766
120PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.81564124
121IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.79549594
122SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.77554396
123LXR_22292898_ChIP-Seq_THP-1_Human0.76493914
124BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.75783890
125SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.75467460
126RARB_24833708_ChIP-Seq_LIVER_Mouse0.75370375
127E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.74635242
128AUTS2_25519132_ChIP-Seq_293T-REX_Human0.74509304
129GATA6_25053715_ChIP-Seq_YYC3_Human0.72667521
130FOXO3_23340844_ChIP-Seq_DLD1_Human0.70657147
131PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.69738840
132RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.69506786
133SALL4_18804426_ChIP-ChIP_XEN_Mouse0.68934856
134IRF1_19129219_ChIP-ChIP_H3396_Human0.66929472
135NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.66870167
136ESET_19884257_ChIP-Seq_ESCs_Mouse0.65859778
137SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.65715488
138BP1_19119308_ChIP-ChIP_Hs578T_Human0.63070637
139SOX2_18692474_ChIP-Seq_MEFs_Mouse0.62681449
140TCF3_18692474_ChIP-Seq_MESCs_Mouse0.62076414
141AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.61856561
142RACK7_27058665_Chip-Seq_MCF-7_Human0.61683313
143NANOG_16518401_ChIP-PET_MESCs_Mouse0.59938296
144OCT4_18692474_ChIP-Seq_MEFs_Mouse0.58993100
145POU5F1_16518401_ChIP-PET_MESCs_Mouse0.58400854
146CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.58203406
147CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.58094655
148RAD21_21589869_ChIP-Seq_MESCs_Mouse0.57648729
149GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.56323207
150CEBPB_22108803_ChIP-Seq_LS180_Human0.55600349
151FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.53632331
152STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.53392687
153ZNF263_19887448_ChIP-Seq_K562_Human0.53344437
154NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.51967461
155Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.50774475
156ERG_21242973_ChIP-ChIP_JURKAT_Human0.50515827
157NANOG_18692474_ChIP-Seq_MEFs_Mouse0.50275514
158NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.50190030
159SPI1_26923725_Chip-Seq_HPCs_Mouse0.49289122
160CSB_26484114_Chip-Seq_FIBROBLAST_Human0.48947178
161FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.48695510
162AR_20517297_ChIP-Seq_VCAP_Human0.48389255
163TET1_21451524_ChIP-Seq_MESCs_Mouse0.48199342
164BCOR_27268052_Chip-Seq_Bcells_Human0.47706602
165NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.47564699
166POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.47205464
167SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.46856448
168GATA3_24758297_ChIP-Seq_MCF-7_Human0.46674805
169P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.46186784
170SOX2_18692474_ChIP-Seq_MESCs_Mouse0.45903217
171MYC_19915707_ChIP-ChIP_AK7_Human0.45753852
172FOXA1_25552417_ChIP-Seq_VCAP_Human0.45309992
173PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.43662270
174PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.43514422
175* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.42607850
176FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.41912903

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.07054775
2MP0002139_abnormal_hepatobiliary_system8.05949554
3MP0005085_abnormal_gallbladder_physiolo5.97222243
4MP0005365_abnormal_bile_salt5.76881139
5MP0008875_abnormal_xenobiotic_pharmacok5.10285728
6MP0003806_abnormal_nucleotide_metabolis3.91940244
7MP0003252_abnormal_bile_duct3.85890115
8MP0005332_abnormal_amino_acid3.40878243
9MP0010329_abnormal_lipoprotein_level3.15461158
10MP0003195_calcinosis3.10716179
11MP0004019_abnormal_vitamin_homeostasis2.94352089
12MP0009840_abnormal_foam_cell2.83566862
13MP0005083_abnormal_biliary_tract2.53973731
14MP0001666_abnormal_nutrient_absorption2.32722608
15MP0000372_irregular_coat_pigmentation2.32202474
16MP0002138_abnormal_hepatobiliary_system2.31772795
17MP0003191_abnormal_cellular_cholesterol2.07121958
18MP0000609_abnormal_liver_physiology2.05903646
19MP0005319_abnormal_enzyme/_coenzyme1.95422459
20MP0002118_abnormal_lipid_homeostasis1.91480600
21MP0009643_abnormal_urine_homeostasis1.86488069
22MP0002938_white_spotting1.77455686
23MP0003011_delayed_dark_adaptation1.73601631
24MP0004043_abnormal_pH_regulation1.64533092
25MP0005584_abnormal_enzyme/coenzyme_acti1.58615434
26MP0010094_abnormal_chromosome_stability1.53748912
27MP0001764_abnormal_homeostasis1.53043561
28MP0003186_abnormal_redox_activity1.52808616
29MP0005451_abnormal_body_composition1.52626992
30MP0003868_abnormal_feces_composition1.50841212
31MP0005187_abnormal_penis_morphology1.48319456
32MP0005636_abnormal_mineral_homeostasis1.40056936
33MP0002254_reproductive_system_inflammat1.39112589
34MP0003705_abnormal_hypodermis_morpholog1.33329148
35MP0008058_abnormal_DNA_repair1.25966635
36MP0003136_yellow_coat_color1.24537027
37MP0005551_abnormal_eye_electrophysiolog1.23847168
38MP0000598_abnormal_liver_morphology1.17589383
39MP0001756_abnormal_urination1.15172203
40MP0003111_abnormal_nucleus_morphology1.12317887
41MP0004264_abnormal_extraembryonic_tissu1.10598959
42MP0003122_maternal_imprinting1.09327804
43MP0001324_abnormal_eye_pigmentation1.07548664
44MP0006036_abnormal_mitochondrial_physio1.04987948
45MP0005646_abnormal_pituitary_gland1.02103123
46MP0003656_abnormal_erythrocyte_physiolo0.98647392
47MP0002136_abnormal_kidney_physiology0.98606523
48MP0000569_abnormal_digit_pigmentation0.97471344
49MP0009697_abnormal_copulation0.97464230
50MP0006292_abnormal_olfactory_placode0.96865462
51MP0006035_abnormal_mitochondrial_morpho0.96849323
52MP0005647_abnormal_sex_gland0.95986948
53MP0009764_decreased_sensitivity_to0.94924409
54MP0000371_diluted_coat_color0.91413787
55MP0005670_abnormal_white_adipose0.89896749
56MP0003693_abnormal_embryo_hatching0.87602050
57MP0002160_abnormal_reproductive_system0.86874113
58MP0005379_endocrine/exocrine_gland_phen0.86429081
59MP0008057_abnormal_DNA_replication0.86411698
60MP0005171_absent_coat_pigmentation0.84496507
61MP0009642_abnormal_blood_homeostasis0.84334477
62MP0001765_abnormal_ion_homeostasis0.83897584
63MP0002876_abnormal_thyroid_physiology0.83006329
64MP0002909_abnormal_adrenal_gland0.82842935
65MP0009763_increased_sensitivity_to0.82172914
66MP0004147_increased_porphyrin_level0.81676675
67MP0008469_abnormal_protein_level0.79905866
68MP0002090_abnormal_vision0.79285678
69MP0001529_abnormal_vocalization0.77338242
70MP0005376_homeostasis/metabolism_phenot0.77194523
71MP0002638_abnormal_pupillary_reflex0.76895795
72MP0000647_abnormal_sebaceous_gland0.76733590
73MP0005084_abnormal_gallbladder_morpholo0.75829995
74MP0005266_abnormal_metabolism0.74900280
75MP0000604_amyloidosis0.74605701
76MP0008932_abnormal_embryonic_tissue0.74545515
77MP0005408_hypopigmentation0.73178335
78MP0001661_extended_life_span0.72717748
79MP0000566_synostosis0.71242947
80MP0005410_abnormal_fertilization0.71175246
81MP0010386_abnormal_urinary_bladder0.70471065
82MP0002078_abnormal_glucose_homeostasis0.70418427
83MP0003567_abnormal_fetal_cardiomyocyte0.70305865
84MP0009765_abnormal_xenobiotic_induced0.68957061
85MP0004957_abnormal_blastocyst_morpholog0.68909421
86MP0003077_abnormal_cell_cycle0.68048237
87MP0003786_premature_aging0.67997974
88MP0003943_abnormal_hepatobiliary_system0.67179007
89MP0001929_abnormal_gametogenesis0.66723169
90MP0005220_abnormal_exocrine_pancreas0.65542133
91MP0010368_abnormal_lymphatic_system0.65106939
92MP0002928_abnormal_bile_duct0.64212092
93MP0005535_abnormal_body_temperature0.63805166
94MP0003121_genomic_imprinting0.62865942
95MP0008961_abnormal_basal_metabolism0.61426563
96MP0005395_other_phenotype0.61185278
97MP0001915_intracranial_hemorrhage0.61062737
98MP0002163_abnormal_gland_morphology0.60840776
99MP0004142_abnormal_muscle_tone0.60120626
100MP0000015_abnormal_ear_pigmentation0.59985156
101MP0003718_maternal_effect0.59935322
102MP0002971_abnormal_brown_adipose0.59843124
103MP0003698_abnormal_male_reproductive0.59782053
104MP0000631_abnormal_neuroendocrine_gland0.59704364
105MP0000427_abnormal_hair_cycle0.58445016
106MP0009053_abnormal_anal_canal0.57470837
107MP0005389_reproductive_system_phenotype0.56160829
108MP0000653_abnormal_sex_gland0.54186608
109MP0003950_abnormal_plasma_membrane0.54155112
110MP0002075_abnormal_coat/hair_pigmentati0.53124206
111MP0001186_pigmentation_phenotype0.53031987
112MP0003315_abnormal_perineum_morphology0.52959671
113MP0008007_abnormal_cellular_replicative0.52584923
114MP0005334_abnormal_fat_pad0.50684386
115MP0005195_abnormal_posterior_eye0.50518847
116MP0005666_abnormal_adipose_tissue0.50246536
117MP0006082_CNS_inflammation0.47156302
118MP0009672_abnormal_birth_weight0.45690337
119MP0002168_other_aberrant_phenotype0.45578118
120MP0003638_abnormal_response/metabolism_0.45215564
121MP0005058_abnormal_lysosome_morphology0.44911999
122MP0002796_impaired_skin_barrier0.43487829
123MP0003329_amyloid_beta_deposits0.42701458
124MP0008872_abnormal_physiological_respon0.42542281
125MP0002135_abnormal_kidney_morphology0.41065814
126MP0002970_abnormal_white_adipose0.41024703
127MP0003953_abnormal_hormone_level0.39341428
128MP0004782_abnormal_surfactant_physiolog0.39112123
129MP0000639_abnormal_adrenal_gland0.39011183
130MP0008873_increased_physiological_sensi0.38379514
131MP0003690_abnormal_glial_cell0.38004377
132MP0000230_abnormal_systemic_arterial0.37613508
133MP0005248_abnormal_Harderian_gland0.37069153
134MP0009115_abnormal_fat_cell0.36850356
135MP0003890_abnormal_embryonic-extraembry0.36168058
136MP0005448_abnormal_energy_balance0.35789599
137MP0005075_abnormal_melanosome_morpholog0.35773070
138MP0002332_abnormal_exercise_endurance0.34243635
139MP0008874_decreased_physiological_sensi0.33303263
140MP0004381_abnormal_hair_follicle0.28767876
141MP0004130_abnormal_muscle_cell0.28654007
142MP0000538_abnormal_urinary_bladder0.27315521
143MP0002092_abnormal_eye_morphology0.24493337
144MP0002269_muscular_atrophy0.24415707
145MP0003075_altered_response_to0.24031772
146MP0005166_decreased_susceptibility_to0.22343262
147MP0002132_abnormal_respiratory_system0.22291446
148MP0000377_abnormal_hair_follicle0.21461541
149MP0001243_abnormal_dermal_layer0.20870691
150MP0002098_abnormal_vibrissa_morphology0.20836855
151MP0001845_abnormal_inflammatory_respons0.19107743

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)6.89218999
2Intrahepatic cholestasis (HP:0001406)6.41709771
3Deep venous thrombosis (HP:0002625)6.08871439
4Abnormality of monocarboxylic acid metabolism (HP:0010996)5.98932821
5Xanthomatosis (HP:0000991)5.62573154
6Hyperglycinuria (HP:0003108)5.28110112
7Prolonged partial thromboplastin time (HP:0003645)5.16759239
8Hypobetalipoproteinemia (HP:0003563)5.15940766
9Hyperglycinemia (HP:0002154)4.95158969
10Abnormality of glycine metabolism (HP:0010895)4.88815549
11Abnormality of serine family amino acid metabolism (HP:0010894)4.88815549
12Abnormality of glutamine family amino acid metabolism (HP:0010902)4.84869111
13Gout (HP:0001997)4.71360976
14Hyperammonemia (HP:0001987)4.68824965
15Ketosis (HP:0001946)4.53588761
16Hyperlipoproteinemia (HP:0010980)4.51303595
17Complement deficiency (HP:0004431)4.30415432
18Abnormality of aspartate family amino acid metabolism (HP:0010899)4.28274900
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.26827390
20Joint hemorrhage (HP:0005261)3.98937610
21Hypolipoproteinemia (HP:0010981)3.90529788
22Abnormality of purine metabolism (HP:0004352)3.70226746
23Abnormality of methionine metabolism (HP:0010901)3.68506182
24Abnormality of nucleobase metabolism (HP:0010932)3.67391941
25Epidermoid cyst (HP:0200040)3.65479028
26Ketoacidosis (HP:0001993)3.64475651
27Abnormality of pyrimidine metabolism (HP:0004353)3.61722330
28Fat malabsorption (HP:0002630)3.52954584
29Abnormality of fatty-acid metabolism (HP:0004359)3.52105830
30Hypoalphalipoproteinemia (HP:0003233)3.50076431
31Abnormality of the common coagulation pathway (HP:0010990)3.50035411
32Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.49885328
33Delayed CNS myelination (HP:0002188)3.46805636
34Abnormality of the intrinsic pathway (HP:0010989)3.46353743
35Hypoglycemic coma (HP:0001325)3.45261070
36Hypochromic microcytic anemia (HP:0004840)3.41208496
37Abnormality of serum amino acid levels (HP:0003112)3.22758018
38Increased purine levels (HP:0004368)3.14770430
39Hyperuricemia (HP:0002149)3.14770430
40Proximal tubulopathy (HP:0000114)3.14738868
41Abnormality of complement system (HP:0005339)3.13033915
42Conjugated hyperbilirubinemia (HP:0002908)3.12907082
43Metabolic acidosis (HP:0001942)3.07722365
44Malnutrition (HP:0004395)3.03674279
45Hypercholesterolemia (HP:0003124)2.94229182
46Abnormality of dicarboxylic acid metabolism (HP:0010995)2.93677112
47Dicarboxylic aciduria (HP:0003215)2.93677112
48Hyperbilirubinemia (HP:0002904)2.93335126
49Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.93196234
50Vascular calcification (HP:0004934)2.88766199
51Alkalosis (HP:0001948)2.88603591
52Lethargy (HP:0001254)2.86614180
53Hepatocellular carcinoma (HP:0001402)2.84480410
54Generalized aminoaciduria (HP:0002909)2.78541172
55Increased serum pyruvate (HP:0003542)2.77681523
56Irritability (HP:0000737)2.70236607
57Abnormality of glycolysis (HP:0004366)2.64309387
58Steatorrhea (HP:0002570)2.59450564
59Skin nodule (HP:0200036)2.55667859
60Rickets (HP:0002748)2.55458216
61Cardiovascular calcification (HP:0011915)2.52556468
62Spastic diplegia (HP:0001264)2.50364747
63Enlarged kidneys (HP:0000105)2.50242695
64Myocardial infarction (HP:0001658)2.49101460
65Vomiting (HP:0002013)2.46977487
66Acute encephalopathy (HP:0006846)2.45952205
67Abnormal cartilage morphology (HP:0002763)2.41762505
68Renal cortical cysts (HP:0000803)2.40846843
69Reduced antithrombin III activity (HP:0001976)2.39163593
70Abnormality of proline metabolism (HP:0010907)2.35485357
71Hydroxyprolinuria (HP:0003080)2.35485357
72Abnormal enzyme/coenzyme activity (HP:0012379)2.35367953
73Abnormality of alanine metabolism (HP:0010916)2.34812359
74Hyperalaninemia (HP:0003348)2.34812359
75Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.34812359
76Glycosuria (HP:0003076)2.34630237
77Abnormality of urine glucose concentration (HP:0011016)2.34630237
78Submucous cleft hard palate (HP:0000176)2.32806092
79Neonatal onset (HP:0003623)2.32627390
80Spontaneous abortion (HP:0005268)2.31813951
81Hyperinsulinemic hypoglycemia (HP:0000825)2.25123556
82Systemic lupus erythematosus (HP:0002725)2.23423077
83Hyperactive renin-angiotensin system (HP:0000841)2.21412603
84Abnormality of the nasal septum (HP:0000419)2.19998641
85Sensorimotor neuropathy (HP:0007141)2.18754359
86Hypokalemic alkalosis (HP:0001949)2.17759801
87Late onset (HP:0003584)2.15356870
88Cerebral edema (HP:0002181)2.14695693
89Abnormality of alkaline phosphatase activity (HP:0004379)2.13065334
90Chromosomal breakage induced by crosslinking agents (HP:0003221)2.10386020
91Hypothermia (HP:0002045)2.09190154
92Chromsome breakage (HP:0040012)2.08405388
93Nephrolithiasis (HP:0000787)2.07832935
94Type II lissencephaly (HP:0007260)2.06346305
95Increased circulating renin level (HP:0000848)2.03598146
96Retinal atrophy (HP:0001105)2.03588904
97Arthropathy (HP:0003040)2.02675749
98Hypoglycemic seizures (HP:0002173)2.00436557
99Pancreatitis (HP:0001733)2.00405347
100Mitral stenosis (HP:0001718)2.00104422
101Abnormal gallbladder morphology (HP:0012437)1.99024230
102Cholelithiasis (HP:0001081)1.98974049
103Elevated alkaline phosphatase (HP:0003155)1.98274496
104Confusion (HP:0001289)1.98104856
105Status epilepticus (HP:0002133)1.96620429
106Abnormal biliary tract physiology (HP:0012439)1.93946588
107Bile duct proliferation (HP:0001408)1.93946588
108Abnormality of the renal cortex (HP:0011035)1.93553648
109Hepatoblastoma (HP:0002884)1.93333295
110Hypophosphatemic rickets (HP:0004912)1.92418478
111Chronic hepatic failure (HP:0100626)1.92104864
112Esophageal varix (HP:0002040)1.91468499
113Glomerulonephritis (HP:0000099)1.87442157
114Brushfield spots (HP:0001088)1.87046544
115Acute necrotizing encephalopathy (HP:0006965)1.86959589
116Hypoplasia of the capital femoral epiphysis (HP:0003090)1.86948604
117Cholecystitis (HP:0001082)1.86139388
118Abnormal gallbladder physiology (HP:0012438)1.86139388
119Fair hair (HP:0002286)1.84683209
120Pancreatic islet-cell hyperplasia (HP:0004510)1.84046570
121Abnormal urine output (HP:0012590)1.83595263
122Abnormality of the ileum (HP:0001549)1.82972801
123Abnormality of transition element cation homeostasis (HP:0011030)1.82235279
124Pancreatic cysts (HP:0001737)1.81608581
125Hepatic necrosis (HP:0002605)1.81337977
126Spastic paraparesis (HP:0002313)1.81121277
127Opisthotonus (HP:0002179)1.81099901
128Hyperphosphaturia (HP:0003109)1.80511338
129Acanthocytosis (HP:0001927)1.80020636
130Menorrhagia (HP:0000132)1.79949852
131Meckel diverticulum (HP:0002245)1.79786987
132Osteomalacia (HP:0002749)1.75538055
133Increased CSF lactate (HP:0002490)1.74350889
134Increased serum lactate (HP:0002151)1.71805811
135Neoplasm of the liver (HP:0002896)1.71207383
136Hemorrhage of the eye (HP:0011885)1.70853989
137Abnormal mitochondria in muscle tissue (HP:0008316)1.70598010
138Pancreatic fibrosis (HP:0100732)1.68212955
139Abnormality of the vitreous humor (HP:0004327)1.67453722
140Abnormality of vitamin metabolism (HP:0100508)1.67379685
141Cerebellar dysplasia (HP:0007033)1.63845056
142Hyperventilation (HP:0002883)1.63199663
143Megaloblastic anemia (HP:0001889)1.62942445
144Aplasia/Hypoplasia of the uvula (HP:0010293)1.62148310
145Poikilocytosis (HP:0004447)1.61100428

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.31552980
2ERN15.11069877
3FGFR43.54029326
4WNK33.41341554
5WNK43.25852339
6SIK13.25053726
7ZAK2.96358889
8CDK122.86231234
9GRK62.74841362
10STK162.74552466
11WEE12.64750031
12OXSR12.63374369
13TRIM282.51164788
14EIF2AK12.49718326
15STK38L2.26061843
16ERBB42.17299138
17MAP2K42.04445830
18CASK1.85288625
19TAOK31.82006550
20INSRR1.81558235
21BRSK21.80591233
22BMPR1B1.77322932
23LATS11.76012416
24ACVR1B1.70914012
25MST1R1.70675787
26NUAK11.70356861
27TLK11.67686831
28SRPK11.67206826
29GRK51.63709376
30BCR1.60751511
31MAPK111.57983739
32GRK11.51070387
33TGFBR21.44299504
34EIF2AK31.37992430
35BUB11.36702975
36PBK1.32615273
37TRIB31.29577870
38MKNK21.29210411
39ABL21.26221702
40PLK41.26084742
41CSF1R1.22405264
42CDC71.20226894
43MAP3K71.20144287
44PINK11.19148228
45NEK11.15301373
46MAPK71.15195379
47ATR1.15170173
48ICK1.13200245
49MAP4K21.12494772
50PKN21.11387536
51FLT31.09067107
52CDK71.07102012
53CHEK21.06304410
54PDK41.05516154
55PDK31.05516154
56TTK1.01715686
57CSNK1G10.99487737
58CSNK1A1L0.98391165
59BRSK10.96647535
60CSNK1G30.95708244
61MAP3K100.94941607
62PRKAA20.94915764
63PIK3CA0.94133145
64NEK20.93250836
65TNIK0.89826946
66STK390.89625930
67CAMK1G0.89620956
68NTRK30.89502332
69CDK30.89364083
70PIK3CG0.88980537
71ADRBK20.87873819
72ATM0.87719425
73PLK30.87425558
74ERBB20.87283154
75TYK20.87170288
76GSK3A0.86941852
77PLK10.86265847
78MAP2K70.85748156
79MAP3K30.85694547
80LATS20.85621589
81PTK60.85025383
82MAP3K40.84056439
83AKT30.83991708
84PRKAA10.83653023
85JAK20.81983568
86NME10.81072837
87MAP2K60.80961713
88WNK10.80875714
89STK100.80698294
90PTK20.80493972
91STK380.78053105
92DYRK1B0.74954830
93MAP2K30.73790784
94MST40.73495016
95MAPK120.72088915
96CAMK40.71645177
97CSNK1G20.71058404
98CDK80.70351930
99IRAK30.70099805
100MAPK40.69644231
101CHEK10.69529060
102ERBB30.69134855
103PRKCZ0.68897038
104DAPK20.68323561
105NEK90.67881443
106CSK0.67226636
107PNCK0.65730326
108MAPK130.65531602
109EPHA20.65435125
110KDR0.65389850
111MET0.64939317
112CSNK2A10.64295004
113PRKACG0.63822022
114SGK4940.63556575
115SGK2230.63556575
116MAPKAPK30.62947923
117FRK0.62886418
118CSNK2A20.62229217
119SGK30.61987930
120PRKCI0.61359931
121MTOR0.61138494
122AURKB0.60439937
123MKNK10.60126127
124PDK20.58726634
125VRK10.57133240
126VRK20.56577670
127CSNK1D0.56569113
128MAPK150.56372785
129CDK40.55056617
130CDK10.54622444
131TSSK60.51077075
132FGFR30.50583195
133CDK20.49464623
134MAP3K110.47956642
135NTRK10.47209250
136DYRK20.46406254
137AKT20.46261434
138TYRO30.46040126
139MATK0.45035131
140FGFR10.44616998
141SGK20.44564334
142FGFR20.44407970
143STK30.44154610
144CDK60.43773927
145EPHB10.43002994
146RPS6KB20.42291402
147PLK20.41790254
148PRKG20.40892510
149RPS6KA50.40580394
150CCNB10.40405683
151CSNK1A10.39356772
152PRKACB0.39299931
153TAOK20.39089750
154IGF1R0.37864617
155PDPK10.33435245
156PRKCG0.33303178
157GRK70.32700036
158RIPK10.32039704
159TIE10.31086729
160MOS0.29706694
161CAMK1D0.28809825
162CSNK1E0.27045337
163PAK30.26662872
164PAK40.26361828
165CAMK2G0.25792195
166JAK10.25063341
167TBK10.24625786

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.01676120
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.50163340
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.20963275
4Nitrogen metabolism_Homo sapiens_hsa009103.10783238
5Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.89423692
6Arginine biosynthesis_Homo sapiens_hsa002202.80768406
7Tryptophan metabolism_Homo sapiens_hsa003802.79620862
8Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.66402355
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.65917324
10Butanoate metabolism_Homo sapiens_hsa006502.49813536
11Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.49075961
12Fatty acid degradation_Homo sapiens_hsa000712.47632025
13* Pentose and glucuronate interconversions_Homo sapiens_hsa000402.37015064
14Complement and coagulation cascades_Homo sapiens_hsa046102.32198854
15Peroxisome_Homo sapiens_hsa041462.18705153
16Propanoate metabolism_Homo sapiens_hsa006402.10870778
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.97193811
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.93135062
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.90846168
20Chemical carcinogenesis_Homo sapiens_hsa052041.84068204
21Histidine metabolism_Homo sapiens_hsa003401.81261509
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.81180453
23PPAR signaling pathway_Homo sapiens_hsa033201.80731643
24beta-Alanine metabolism_Homo sapiens_hsa004101.79363025
25Steroid hormone biosynthesis_Homo sapiens_hsa001401.78733704
26Fatty acid metabolism_Homo sapiens_hsa012121.77099962
27Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.71797914
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.70808027
29Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.69529986
30Selenocompound metabolism_Homo sapiens_hsa004501.61730324
31Retinol metabolism_Homo sapiens_hsa008301.59088018
32Cyanoamino acid metabolism_Homo sapiens_hsa004601.58897139
33Vitamin B6 metabolism_Homo sapiens_hsa007501.56402597
34Bile secretion_Homo sapiens_hsa049761.56352545
35Pyruvate metabolism_Homo sapiens_hsa006201.55527262
36Phenylalanine metabolism_Homo sapiens_hsa003601.45039789
37Caffeine metabolism_Homo sapiens_hsa002321.40254105
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39394390
39Folate biosynthesis_Homo sapiens_hsa007901.39269562
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.33407788
41Staphylococcus aureus infection_Homo sapiens_hsa051501.32659087
42Carbon metabolism_Homo sapiens_hsa012001.31177802
43Sulfur metabolism_Homo sapiens_hsa009201.30231491
44Starch and sucrose metabolism_Homo sapiens_hsa005001.29174555
45Biosynthesis of amino acids_Homo sapiens_hsa012301.28809515
46Tyrosine metabolism_Homo sapiens_hsa003501.27096842
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.26380804
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.19385825
49Vitamin digestion and absorption_Homo sapiens_hsa049771.18948025
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.12678291
51Arginine and proline metabolism_Homo sapiens_hsa003301.10965484
52Fatty acid elongation_Homo sapiens_hsa000621.10296748
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.09664717
54ABC transporters_Homo sapiens_hsa020101.03946128
55Steroid biosynthesis_Homo sapiens_hsa001001.01156780
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.99511027
57Sulfur relay system_Homo sapiens_hsa041220.98881909
58Homologous recombination_Homo sapiens_hsa034400.98846308
59Lysine degradation_Homo sapiens_hsa003100.96904135
60Fat digestion and absorption_Homo sapiens_hsa049750.93537919
61RNA polymerase_Homo sapiens_hsa030200.91950617
62Fanconi anemia pathway_Homo sapiens_hsa034600.88044866
63Glutathione metabolism_Homo sapiens_hsa004800.87717375
64Protein export_Homo sapiens_hsa030600.87026013
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86549422
66One carbon pool by folate_Homo sapiens_hsa006700.83231857
67Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81582387
68DNA replication_Homo sapiens_hsa030300.80552725
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78023436
70Glycerolipid metabolism_Homo sapiens_hsa005610.77706375
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74251550
72Pentose phosphate pathway_Homo sapiens_hsa000300.72164581
73Basal transcription factors_Homo sapiens_hsa030220.70042773
74Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.69465620
75Fructose and mannose metabolism_Homo sapiens_hsa000510.69185591
76Proteasome_Homo sapiens_hsa030500.67386387
77Mismatch repair_Homo sapiens_hsa034300.65098007
78Pyrimidine metabolism_Homo sapiens_hsa002400.64510838
79Nucleotide excision repair_Homo sapiens_hsa034200.56954490
80Oxidative phosphorylation_Homo sapiens_hsa001900.56635476
81Non-homologous end-joining_Homo sapiens_hsa034500.56383569
82* Metabolic pathways_Homo sapiens_hsa011000.52247756
83Galactose metabolism_Homo sapiens_hsa000520.44234589
84RNA transport_Homo sapiens_hsa030130.40707411
85alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.39196584
86N-Glycan biosynthesis_Homo sapiens_hsa005100.37870435
87Base excision repair_Homo sapiens_hsa034100.36949903
88Purine metabolism_Homo sapiens_hsa002300.34999001
89Sphingolipid metabolism_Homo sapiens_hsa006000.33209901
90Parkinsons disease_Homo sapiens_hsa050120.31300767
91RNA degradation_Homo sapiens_hsa030180.28485794
92Linoleic acid metabolism_Homo sapiens_hsa005910.28401028
93Fatty acid biosynthesis_Homo sapiens_hsa000610.27102078
94Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.23197906
95Huntingtons disease_Homo sapiens_hsa050160.22947574
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.21204555
97Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.20615499
98Insulin resistance_Homo sapiens_hsa049310.19508278
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.17726404
100Phototransduction_Homo sapiens_hsa047440.17491347
101Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.16211997
102Prion diseases_Homo sapiens_hsa050200.15012667
103Arachidonic acid metabolism_Homo sapiens_hsa005900.13240579
104Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.08139483
105AMPK signaling pathway_Homo sapiens_hsa041520.06194537
106Glycosaminoglycan degradation_Homo sapiens_hsa005310.04084118
107Glucagon signaling pathway_Homo sapiens_hsa049220.01980333
108Regulation of autophagy_Homo sapiens_hsa041400.01928501
109Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2002504
110Hepatitis C_Homo sapiens_hsa05160-0.1856105
111Insulin signaling pathway_Homo sapiens_hsa04910-0.1743592
112Bladder cancer_Homo sapiens_hsa05219-0.1697154
113Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1586629
114Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1571589
115Lysosome_Homo sapiens_hsa04142-0.1553203
116Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1400361
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1333338
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.1057947
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603-0.0977798
120Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.0770729
121Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0644698
122Mineral absorption_Homo sapiens_hsa04978-0.0491727
123Protein digestion and absorption_Homo sapiens_hsa04974-0.0292829
124Other glycan degradation_Homo sapiens_hsa00511-0.0105351
125Renin-angiotensin system_Homo sapiens_hsa04614-0.0061518

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »