YAE1D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.68571031
2ATP synthesis coupled proton transport (GO:0015986)5.20246079
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.20246079
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.63082370
5axon ensheathment in central nervous system (GO:0032291)4.51959855
6central nervous system myelination (GO:0022010)4.51959855
7protein neddylation (GO:0045116)4.31764047
8proteasome assembly (GO:0043248)4.25531642
9fatty acid elongation (GO:0030497)4.21197846
10mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.16766137
11mitochondrial respiratory chain complex I assembly (GO:0032981)4.16766137
12NADH dehydrogenase complex assembly (GO:0010257)4.16766137
13respiratory electron transport chain (GO:0022904)4.08605009
14chaperone-mediated protein transport (GO:0072321)4.05522860
15cullin deneddylation (GO:0010388)4.02365651
16electron transport chain (GO:0022900)3.96338131
17water-soluble vitamin biosynthetic process (GO:0042364)3.90605494
18establishment of protein localization to mitochondrial membrane (GO:0090151)3.85032426
19L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.79425119
20protein complex biogenesis (GO:0070271)3.78173502
217-methylguanosine RNA capping (GO:0009452)3.60932453
22RNA capping (GO:0036260)3.60932453
23transcription elongation from RNA polymerase III promoter (GO:0006385)3.59361128
24termination of RNA polymerase III transcription (GO:0006386)3.59361128
25respiratory chain complex IV assembly (GO:0008535)3.58435877
26mitochondrial respiratory chain complex assembly (GO:0033108)3.53974914
277-methylguanosine mRNA capping (GO:0006370)3.53704538
28protein deneddylation (GO:0000338)3.51478301
29exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.47632919
30nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.47399643
31cholesterol biosynthetic process (GO:0006695)3.37974645
32ubiquinone metabolic process (GO:0006743)3.24896838
33histone exchange (GO:0043486)3.21270340
34cytochrome complex assembly (GO:0017004)3.20536608
35ribosomal small subunit assembly (GO:0000028)3.19761676
36amino acid salvage (GO:0043102)3.19678651
37L-methionine salvage (GO:0071267)3.19678651
38L-methionine biosynthetic process (GO:0071265)3.19678651
39DNA double-strand break processing (GO:0000729)3.18215951
40long-chain fatty acid biosynthetic process (GO:0042759)3.16242117
41response to redox state (GO:0051775)3.15487151
42transcription elongation from RNA polymerase I promoter (GO:0006362)3.11544651
43behavioral response to nicotine (GO:0035095)3.11309992
44negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.08990477
45isoprenoid biosynthetic process (GO:0008299)3.07993556
46CENP-A containing nucleosome assembly (GO:0034080)3.05908625
47ubiquinone biosynthetic process (GO:0006744)3.04212922
48quinone biosynthetic process (GO:1901663)3.04212922
49RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.04056107
50tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.04056107
51limb bud formation (GO:0060174)3.03896144
52purine nucleobase biosynthetic process (GO:0009113)3.02337337
53otic vesicle formation (GO:0030916)3.00863571
54GTP biosynthetic process (GO:0006183)2.98331179
55protein targeting to mitochondrion (GO:0006626)2.96950989
56termination of RNA polymerase I transcription (GO:0006363)2.96341262
57nonmotile primary cilium assembly (GO:0035058)2.96148283
58platelet dense granule organization (GO:0060155)2.95710255
59regulation of cellular amino acid metabolic process (GO:0006521)2.95339254
60sterol biosynthetic process (GO:0016126)2.95176824
61positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.95077697
62protein K6-linked ubiquitination (GO:0085020)2.94344883
63nucleobase biosynthetic process (GO:0046112)2.93032759
64cotranslational protein targeting to membrane (GO:0006613)2.92149641
65SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.91392782
66establishment of protein localization to mitochondrion (GO:0072655)2.89695929
67ventricular cardiac muscle cell development (GO:0055015)2.89420539
68regulation of mitochondrial translation (GO:0070129)2.88574493
69anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.87953446
70regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.86952664
71transcription from RNA polymerase I promoter (GO:0006360)2.86282208
72negative regulation of ligase activity (GO:0051352)2.86172736
73negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.86172736
74regulation of mitotic spindle checkpoint (GO:1903504)2.85873634
75regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.85873634
76chromatin remodeling at centromere (GO:0031055)2.84699814
77DNA replication-independent nucleosome assembly (GO:0006336)2.81994935
78DNA replication-independent nucleosome organization (GO:0034724)2.81994935
79protein targeting to ER (GO:0045047)2.81670879
80negative regulation of DNA-dependent DNA replication (GO:2000104)2.81626739
81histone mRNA metabolic process (GO:0008334)2.80279390
82translational termination (GO:0006415)2.79508469
83substantia nigra development (GO:0021762)2.78686456
84guanosine-containing compound biosynthetic process (GO:1901070)2.78258920
85microtubule polymerization or depolymerization (GO:0031109)2.77976371
86establishment of integrated proviral latency (GO:0075713)2.77218369
87protein localization to mitochondrion (GO:0070585)2.75740390
88oxidative phosphorylation (GO:0006119)2.75429012
89translation (GO:0006412)2.75067917
90replication fork processing (GO:0031297)2.74728840
91viral transcription (GO:0019083)2.73915959
92intraciliary transport (GO:0042073)2.73805665
93anterograde synaptic vesicle transport (GO:0048490)2.71933272
94establishment of protein localization to endoplasmic reticulum (GO:0072599)2.71368482
95DNA damage response, detection of DNA damage (GO:0042769)2.69655017
96peptidyl-histidine modification (GO:0018202)2.69357082
97transcription initiation from RNA polymerase I promoter (GO:0006361)2.68331727
98ribosomal large subunit biogenesis (GO:0042273)2.67607845
99transcription-coupled nucleotide-excision repair (GO:0006283)2.67205969
100rRNA modification (GO:0000154)2.66208954
101signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.64632800
102intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.64632800
103DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.64510447
104DNA replication checkpoint (GO:0000076)2.63949292
105protein localization to endoplasmic reticulum (GO:0070972)2.63627319
106cellular component biogenesis (GO:0044085)2.62555775
107UTP biosynthetic process (GO:0006228)2.62506701
108signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.62400694
109signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.62400694
110signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.62400694
111hydrogen ion transmembrane transport (GO:1902600)2.61952210
112purine nucleoside triphosphate biosynthetic process (GO:0009145)2.61910620
113positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.61653529
114inner mitochondrial membrane organization (GO:0007007)2.59470285
115spliceosomal complex assembly (GO:0000245)2.59159141
116lateral sprouting from an epithelium (GO:0060601)2.58981929
117purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.58649093
118protein-cofactor linkage (GO:0018065)2.57973789
119sequestering of actin monomers (GO:0042989)2.56631941
120organelle disassembly (GO:1903008)2.55585173
121signal transduction involved in DNA integrity checkpoint (GO:0072401)2.54948524
122signal transduction involved in DNA damage checkpoint (GO:0072422)2.54948524
123neurotransmitter uptake (GO:0001504)2.54284189
124pyrimidine nucleobase catabolic process (GO:0006208)2.54055802
125recombinational repair (GO:0000725)2.53647489
126signal transduction involved in cell cycle checkpoint (GO:0072395)2.52265426
127positive regulation of ligase activity (GO:0051351)2.52124185
128dopamine transport (GO:0015872)2.51895357
129double-strand break repair via homologous recombination (GO:0000724)2.50886129
130regulation of meiosis I (GO:0060631)2.50845536
131DNA catabolic process, exonucleolytic (GO:0000738)2.48137734
132pseudouridine synthesis (GO:0001522)2.47729735
133ATP biosynthetic process (GO:0006754)2.47311355
134establishment of mitochondrion localization (GO:0051654)2.47238843
135kinetochore assembly (GO:0051382)2.46751143
136intracellular protein transmembrane import (GO:0044743)2.46037397
137spliceosomal snRNP assembly (GO:0000387)2.45928081
138ribosomal small subunit biogenesis (GO:0042274)2.45504388
139myelination (GO:0042552)2.45297099
140ribosome assembly (GO:0042255)2.44738921
141preassembly of GPI anchor in ER membrane (GO:0016254)2.44578593
142transcription elongation from RNA polymerase II promoter (GO:0006368)2.44176057
143regulation of cellular amine metabolic process (GO:0033238)2.44031540
144maturation of SSU-rRNA (GO:0030490)2.42379377

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.21805285
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.36585192
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.91002272
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.25175736
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.11373321
6MYC_18555785_ChIP-Seq_MESCs_Mouse2.89733650
7CREB1_15753290_ChIP-ChIP_HEK293T_Human2.79189194
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.76961140
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.75742577
10CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.72578220
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.49749530
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.48886934
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.32599895
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.29592603
15FUS_26573619_Chip-Seq_HEK293_Human2.21112065
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.05229941
17RBPJ_22232070_ChIP-Seq_NCS_Mouse2.03740930
18E2F7_22180533_ChIP-Seq_HELA_Human1.89767669
19MYC_19030024_ChIP-ChIP_MESCs_Mouse1.87273599
20AR_21909140_ChIP-Seq_LNCAP_Human1.87091074
21SALL1_21062744_ChIP-ChIP_HESCs_Human1.86999908
22PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.86456859
23TAF15_26573619_Chip-Seq_HEK293_Human1.84589553
24MYC_18358816_ChIP-ChIP_MESCs_Mouse1.82315389
25SRF_21415370_ChIP-Seq_HL-1_Mouse1.80580239
26THAP11_20581084_ChIP-Seq_MESCs_Mouse1.78143999
27IGF1R_20145208_ChIP-Seq_DFB_Human1.77721559
28VDR_22108803_ChIP-Seq_LS180_Human1.75223764
29E2F4_17652178_ChIP-ChIP_JURKAT_Human1.70321390
30ELK1_19687146_ChIP-ChIP_HELA_Human1.68132446
31POU5F1_16153702_ChIP-ChIP_HESCs_Human1.66334769
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65903423
33EWS_26573619_Chip-Seq_HEK293_Human1.64466378
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.61764884
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.59912392
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56734257
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53593655
38DCP1A_22483619_ChIP-Seq_HELA_Human1.53110949
39VDR_23849224_ChIP-Seq_CD4+_Human1.52120442
40NELFA_20434984_ChIP-Seq_ESCs_Mouse1.46347276
41SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45120146
42IRF1_19129219_ChIP-ChIP_H3396_Human1.43228956
43GBX2_23144817_ChIP-Seq_PC3_Human1.41802225
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40089632
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.37811287
46* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37645449
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.34482422
48POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33861864
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.31393492
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26684193
51GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24747704
52RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.24437435
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24419896
54ER_23166858_ChIP-Seq_MCF-7_Human1.22704278
55MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.22035198
56KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.21298870
57ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.21298324
58SOX2_18555785_ChIP-Seq_MESCs_Mouse1.21268696
59XRN2_22483619_ChIP-Seq_HELA_Human1.20630199
60BMI1_23680149_ChIP-Seq_NPCS_Mouse1.20407762
61PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19229695
62MYCN_18555785_ChIP-Seq_MESCs_Mouse1.17451649
63CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16800591
64PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16755308
65SOX17_20123909_ChIP-Seq_XEN_Mouse1.16660316
66GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15501071
67FLI1_27457419_Chip-Seq_LIVER_Mouse1.15344549
68TP53_22573176_ChIP-Seq_HFKS_Human1.15289950
69MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.14797794
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.13971987
71TTF2_22483619_ChIP-Seq_HELA_Human1.12152217
72SOX2_16153702_ChIP-ChIP_HESCs_Human1.11088556
73FOXP3_21729870_ChIP-Seq_TREG_Human1.11085843
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.09936164
75EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09877377
76EZH2_22144423_ChIP-Seq_EOC_Human1.09549959
77GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.08276925
78ZNF274_21170338_ChIP-Seq_K562_Hela1.08186296
79MYC_18940864_ChIP-ChIP_HL60_Human1.07630103
80GABP_19822575_ChIP-Seq_HepG2_Human1.07525352
81P300_19829295_ChIP-Seq_ESCs_Human1.07302379
82FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06669195
83EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.03872499
84PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03002886
85E2F1_21310950_ChIP-Seq_MCF-7_Human1.01399616
86ELK1_22589737_ChIP-Seq_MCF10A_Human1.00268469
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98487517
88RNF2_27304074_Chip-Seq_NSC_Mouse0.98370865
89TP63_19390658_ChIP-ChIP_HaCaT_Human0.98257816
90IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97964817
91CBP_20019798_ChIP-Seq_JUKART_Human0.97964817
92CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96450344
93ELF1_17652178_ChIP-ChIP_JURKAT_Human0.95882771
94SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94425862
95ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.94224166
96YY1_21170310_ChIP-Seq_MESCs_Mouse0.93351711
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93173284
98EZH2_27294783_Chip-Seq_NPCs_Mouse0.92972443
99SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92835523
100POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.91768881
101BCAT_22108803_ChIP-Seq_LS180_Human0.91112535
102MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.90628155
103SOX2_19829295_ChIP-Seq_ESCs_Human0.90521912
104NANOG_19829295_ChIP-Seq_ESCs_Human0.90521912
105MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89466474
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89461762
107HTT_18923047_ChIP-ChIP_STHdh_Human0.89411754
108FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.89354541
109SOX9_26525672_Chip-Seq_HEART_Mouse0.87725815
110FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.87386498
111SMAD3_21741376_ChIP-Seq_EPCs_Human0.87232723
112PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.86853548
113NANOG_18555785_Chip-Seq_ESCs_Mouse0.84785899
114TOP2B_26459242_ChIP-Seq_MCF-7_Human0.84313411
115NANOG_16153702_ChIP-ChIP_HESCs_Human0.83104638
116MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.83049453
117HOXB4_20404135_ChIP-ChIP_EML_Mouse0.82819063
118EP300_21415370_ChIP-Seq_HL-1_Mouse0.82465991
119EZH2_27304074_Chip-Seq_ESCs_Mouse0.82354383
120PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.82054074

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization2.94888552
2MP0000566_synostosis2.60265274
3MP0003136_yellow_coat_color2.57041425
4MP0008789_abnormal_olfactory_epithelium2.51444710
5MP0003806_abnormal_nucleotide_metabolis2.49557696
6MP0009697_abnormal_copulation2.49205762
7MP0003123_paternal_imprinting2.41026554
8MP0001905_abnormal_dopamine_level2.28411566
9MP0003950_abnormal_plasma_membrane2.11792115
10MP0004215_abnormal_myocardial_fiber2.04589556
11MP0005499_abnormal_olfactory_system1.97751221
12MP0005394_taste/olfaction_phenotype1.97751221
13MP0003880_abnormal_central_pattern1.94110896
14MP0008057_abnormal_DNA_replication1.80742625
15MP0002837_dystrophic_cardiac_calcinosis1.77989577
16MP0002938_white_spotting1.77314165
17MP0004957_abnormal_blastocyst_morpholog1.73336629
18MP0003937_abnormal_limbs/digits/tail_de1.73087920
19MP0003011_delayed_dark_adaptation1.72856153
20MP0005084_abnormal_gallbladder_morpholo1.67622331
21MP0009250_abnormal_appendicular_skeleto1.66721675
22MP0004134_abnormal_chest_morphology1.66196708
23MP0004084_abnormal_cardiac_muscle1.61603261
24MP0003718_maternal_effect1.61150208
25MP0001485_abnormal_pinna_reflex1.61079718
26MP0002102_abnormal_ear_morphology1.58884778
27MP0008932_abnormal_embryonic_tissue1.58804338
28MP0003121_genomic_imprinting1.52875338
29MP0000749_muscle_degeneration1.52692237
30MP0008995_early_reproductive_senescence1.52561596
31MP0003693_abnormal_embryo_hatching1.50744555
32MP0008877_abnormal_DNA_methylation1.48722978
33MP0002282_abnormal_trachea_morphology1.46758577
34MP0001984_abnormal_olfaction1.46130885
35MP0006138_congestive_heart_failure1.44185198
36MP0000049_abnormal_middle_ear1.43138400
37MP0003195_calcinosis1.42718591
38MP0010094_abnormal_chromosome_stability1.38861587
39MP0000920_abnormal_myelination1.38655358
40MP0006035_abnormal_mitochondrial_morpho1.37617159
41MP0006072_abnormal_retinal_apoptosis1.37143320
42MP0003137_abnormal_impulse_conducting1.35868724
43MP0003122_maternal_imprinting1.35218215
44MP0001968_abnormal_touch/_nociception1.33804910
45MP0004036_abnormal_muscle_relaxation1.33651169
46MP0002751_abnormal_autonomic_nervous1.31483456
47MP0006292_abnormal_olfactory_placode1.30586600
48MP0000647_abnormal_sebaceous_gland1.29192040
49MP0008058_abnormal_DNA_repair1.28622982
50MP0005330_cardiomyopathy1.26821373
51MP0006036_abnormal_mitochondrial_physio1.24805485
52MP0000778_abnormal_nervous_system1.24006091
53MP0005187_abnormal_penis_morphology1.23672254
54MP0000762_abnormal_tongue_morphology1.23152830
55MP0010030_abnormal_orbit_morphology1.23065995
56MP0009384_cardiac_valve_regurgitation1.22326531
57MP0004147_increased_porphyrin_level1.20276606
58MP0001299_abnormal_eye_distance/1.20179875
59MP0003938_abnormal_ear_development1.20003486
60MP0003787_abnormal_imprinting1.19754729
61MP0002249_abnormal_larynx_morphology1.17057231
62MP0005248_abnormal_Harderian_gland1.16721592
63MP0005645_abnormal_hypothalamus_physiol1.16494606
64MP0003646_muscle_fatigue1.12977074
65MP0004142_abnormal_muscle_tone1.12468573
66MP0004145_abnormal_muscle_electrophysio1.12396932
67MP0005551_abnormal_eye_electrophysiolog1.10821598
68MP0001293_anophthalmia1.10664602
69MP0002653_abnormal_ependyma_morphology1.10254590
70MP0002972_abnormal_cardiac_muscle1.09924082
71MP0004085_abnormal_heartbeat1.09870947
72MP0001486_abnormal_startle_reflex1.09827855
73MP0003941_abnormal_skin_development1.08387703
74MP0002127_abnormal_cardiovascular_syste1.08387612
75MP0000372_irregular_coat_pigmentation1.07628127
76MP0002160_abnormal_reproductive_system1.07396196
77MP0003567_abnormal_fetal_cardiomyocyte1.07110714
78MP0000631_abnormal_neuroendocrine_gland1.05847312
79MP0005171_absent_coat_pigmentation1.05805704
80MP0009046_muscle_twitch1.05603942
81MP0003077_abnormal_cell_cycle1.04154432
82MP0002210_abnormal_sex_determination1.03078462
83MP0003890_abnormal_embryonic-extraembry1.02745995
84MP0005646_abnormal_pituitary_gland1.02213151
85MP0004133_heterotaxia1.00985383
86MP0000751_myopathy0.99469918
87MP0005195_abnormal_posterior_eye0.98209433
88MP0004270_analgesia0.98124969
89MP0002234_abnormal_pharynx_morphology0.97966276
90MP0003942_abnormal_urinary_system0.97721192
91MP0002272_abnormal_nervous_system0.97206999
92MP0002638_abnormal_pupillary_reflex0.96850710
93MP0008260_abnormal_autophagy0.96718181
94MP0005391_vision/eye_phenotype0.96316417
95MP0001963_abnormal_hearing_physiology0.96126487
96MP0000026_abnormal_inner_ear0.96077597
97MP0009379_abnormal_foot_pigmentation0.95468473
98MP0003111_abnormal_nucleus_morphology0.94924305
99MP0002736_abnormal_nociception_after0.94459876
100MP0004484_altered_response_of0.92947463
101MP0003755_abnormal_palate_morphology0.92668373
102MP0001177_atelectasis0.91321834
103MP0008775_abnormal_heart_ventricle0.91163780
104MP0000537_abnormal_urethra_morphology0.90977168
105MP0002697_abnormal_eye_size0.90784177
106MP0002233_abnormal_nose_morphology0.90441822
107MP0002095_abnormal_skin_pigmentation0.90367597
108MP0010386_abnormal_urinary_bladder0.90353224
109MP0002184_abnormal_innervation0.90286154
110MP0003315_abnormal_perineum_morphology0.90137694
111MP0005620_abnormal_muscle_contractility0.90036481
112MP0006276_abnormal_autonomic_nervous0.88469524
113MP0004742_abnormal_vestibular_system0.87605732
114MP0001324_abnormal_eye_pigmentation0.86491314
115MP0005409_darkened_coat_color0.86462293
116MP0003786_premature_aging0.86328567
117MP0009745_abnormal_behavioral_response0.86141722
118MP0003385_abnormal_body_wall0.85997313
119MP0005423_abnormal_somatic_nervous0.85108002
120MP0000653_abnormal_sex_gland0.84554674
121MP0001929_abnormal_gametogenesis0.84525071
122MP0008872_abnormal_physiological_respon0.84417703
123MP0002752_abnormal_somatic_nervous0.83363155
124MP0002557_abnormal_social/conspecific_i0.83348303
125MP0001730_embryonic_growth_arrest0.83329168
126MP0008007_abnormal_cellular_replicative0.83144456
127MP0005253_abnormal_eye_physiology0.82579470
128MP0004885_abnormal_endolymph0.82422043
129MP0001145_abnormal_male_reproductive0.81870883
130MP0001188_hyperpigmentation0.81035599
131MP0003119_abnormal_digestive_system0.80425996
132MP0003221_abnormal_cardiomyocyte_apopto0.80197505
133MP0001286_abnormal_eye_development0.78738515
134MP0001440_abnormal_grooming_behavior0.77887701
135MP0005385_cardiovascular_system_phenoty0.77429167
136MP0001544_abnormal_cardiovascular_syste0.77429167
137MP0002163_abnormal_gland_morphology0.77134511
138MP0003698_abnormal_male_reproductive0.75731076
139MP0002277_abnormal_respiratory_mucosa0.75671705
140MP0000427_abnormal_hair_cycle0.75426659
141MP0003186_abnormal_redox_activity0.75307961
142MP0009053_abnormal_anal_canal0.74911388

Predicted human phenotypes

RankGene SetZ-score
1Increased serum pyruvate (HP:0003542)5.43810241
2Abnormality of glycolysis (HP:0004366)5.43810241
3Acute necrotizing encephalopathy (HP:0006965)4.91488224
4Abnormal mitochondria in muscle tissue (HP:0008316)4.48402267
5Acute encephalopathy (HP:0006846)4.10731701
6Progressive macrocephaly (HP:0004481)4.05383568
7Mitochondrial inheritance (HP:0001427)3.82498305
8Increased CSF lactate (HP:0002490)3.81034905
9Irregular epiphyses (HP:0010582)3.62221950
10Birth length less than 3rd percentile (HP:0003561)3.26552539
11Increased hepatocellular lipid droplets (HP:0006565)3.22537836
12Hepatocellular necrosis (HP:0001404)3.06733994
13Colon cancer (HP:0003003)3.05784971
14Breast hypoplasia (HP:0003187)3.04705765
15Lipid accumulation in hepatocytes (HP:0006561)2.96166708
16Cerebral edema (HP:0002181)2.96035302
17Leukodystrophy (HP:0002415)2.94852404
18Pancreatic cysts (HP:0001737)2.88019436
19Abnormality of midbrain morphology (HP:0002418)2.87606831
20Molar tooth sign on MRI (HP:0002419)2.87606831
21Increased serum lactate (HP:0002151)2.83799871
223-Methylglutaconic aciduria (HP:0003535)2.72778034
23Hepatic necrosis (HP:0002605)2.72615383
24Degeneration of the lateral corticospinal tracts (HP:0002314)2.72446146
25Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.72446146
26Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.68630774
27Renal Fanconi syndrome (HP:0001994)2.67724386
28Cerebral hypomyelination (HP:0006808)2.67382953
29Respiratory failure (HP:0002878)2.66070742
30Exercise intolerance (HP:0003546)2.62834568
31Nephronophthisis (HP:0000090)2.57654970
32Lactic acidosis (HP:0003128)2.50419166
33Methylmalonic acidemia (HP:0002912)2.49521110
34Optic disc pallor (HP:0000543)2.41960317
35Vitreoretinal degeneration (HP:0000655)2.41240280
36Congenital, generalized hypertrichosis (HP:0004540)2.35834053
37Abnormality of the phalanges of the 2nd finger (HP:0009541)2.35601656
38Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.34700493
39Abnormality of the labia minora (HP:0012880)2.32815125
40Supernumerary spleens (HP:0009799)2.31158770
41Abnormality of alanine metabolism (HP:0010916)2.27564948
42Hyperalaninemia (HP:0003348)2.27564948
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.27564948
44Abnormality of serum amino acid levels (HP:0003112)2.27291776
45Macrocytic anemia (HP:0001972)2.26573673
46Septo-optic dysplasia (HP:0100842)2.26305102
47Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.25169128
48Parakeratosis (HP:0001036)2.25091955
49Reticulocytopenia (HP:0001896)2.23464798
50Esophageal atresia (HP:0002032)2.22509236
51Hypoplastic left heart (HP:0004383)2.22441670
52Abnormality of incisor morphology (HP:0011063)2.20945719
53Congenital malformation of the right heart (HP:0011723)2.20357421
54Double outlet right ventricle (HP:0001719)2.20357421
55Abnormal number of erythroid precursors (HP:0012131)2.20270092
56Pendular nystagmus (HP:0012043)2.15721105
57Microvesicular hepatic steatosis (HP:0001414)2.09878852
58Hypoplastic pelvis (HP:0008839)2.09236195
59Sclerocornea (HP:0000647)2.05485382
60Anencephaly (HP:0002323)2.05461816
61Methylmalonic aciduria (HP:0012120)2.04630701
62Autoamputation (HP:0001218)2.02157377
63Increased intramyocellular lipid droplets (HP:0012240)2.01177426
64Abnormality of serine family amino acid metabolism (HP:0010894)2.00772896
65Abnormality of glycine metabolism (HP:0010895)2.00772896
66Abnormality of cells of the erythroid lineage (HP:0012130)1.99940093
67Progressive external ophthalmoplegia (HP:0000590)1.99727249
68Small epiphyses (HP:0010585)1.99690910
69Hypoplastic heart (HP:0001961)1.99309638
70Gastrointestinal atresia (HP:0002589)1.98663228
71Abnormality of the renal medulla (HP:0100957)1.98379004
72Exertional dyspnea (HP:0002875)1.96290569
73Aplasia/Hypoplasia of the tongue (HP:0010295)1.95481366
74Triphalangeal thumb (HP:0001199)1.94948144
75Respiratory difficulties (HP:0002880)1.93973722
76Aplasia/Hypoplasia of the uvula (HP:0010293)1.93871258
77Cystic liver disease (HP:0006706)1.92605792
78Short tibia (HP:0005736)1.92353671
79Meckel diverticulum (HP:0002245)1.92315892
80Adrenal hypoplasia (HP:0000835)1.92195824
81Absent epiphyses (HP:0010577)1.91675807
82Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.91675807
83Postaxial foot polydactyly (HP:0001830)1.91214568
84Oligodactyly (hands) (HP:0001180)1.90241122
85Preaxial hand polydactyly (HP:0001177)1.90217962
86Abnormality of vitamin B metabolism (HP:0004340)1.88795568
87Abnormal lung lobation (HP:0002101)1.88734424
88X-linked dominant inheritance (HP:0001423)1.88726231
89Median cleft lip (HP:0000161)1.88463801
90Abnormality of the vitamin B12 metabolism (HP:0004341)1.88272405
91Stenosis of the external auditory canal (HP:0000402)1.88249742
92Carpal bone hypoplasia (HP:0001498)1.87942927
93Abnormality of chromosome stability (HP:0003220)1.87597154
94Decreased activity of mitochondrial respiratory chain (HP:0008972)1.86754579
95Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.86754579
96CNS hypomyelination (HP:0003429)1.86536961
97Epiphyseal dysplasia (HP:0002656)1.85931736
98Morphological abnormality of the inner ear (HP:0011390)1.83732613
99Abnormality of the ileum (HP:0001549)1.83071572
100Medial flaring of the eyebrow (HP:0010747)1.82237031
101True hermaphroditism (HP:0010459)1.81550827
102Degeneration of anterior horn cells (HP:0002398)1.81044201
103Abnormality of the anterior horn cell (HP:0006802)1.81044201
104Aplasia/Hypoplasia of the tibia (HP:0005772)1.80750143
105Optic nerve hypoplasia (HP:0000609)1.80725314
106Intestinal atresia (HP:0011100)1.80242078
107CNS demyelination (HP:0007305)1.78723681
108Bifid tongue (HP:0010297)1.77193507
109Split foot (HP:0001839)1.76250079
110Alacrima (HP:0000522)1.75867864
111Aplasia/Hypoplasia involving the musculature (HP:0001460)1.74706423
112Anophthalmia (HP:0000528)1.74137117
113Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.73542329
114Nasolacrimal duct obstruction (HP:0000579)1.73516642
115Abnormality of urine glucose concentration (HP:0011016)1.73384679
116Glycosuria (HP:0003076)1.73384679
117Postaxial hand polydactyly (HP:0001162)1.73222566
118Sensory axonal neuropathy (HP:0003390)1.72461219
119Mixed hearing impairment (HP:0000410)1.71784771
120Occipital encephalocele (HP:0002085)1.71300878
121Abnormality of placental membranes (HP:0011409)1.70867986
122Amniotic constriction ring (HP:0009775)1.70867986
123Vaginal atresia (HP:0000148)1.70357621
124Genital tract atresia (HP:0001827)1.69303479
125Patent foramen ovale (HP:0001655)1.69041064
126Poor coordination (HP:0002370)1.68052928
127Absent septum pellucidum (HP:0001331)1.68037916
128Abnormality of renal resorption (HP:0011038)1.67403864
129Gait imbalance (HP:0002141)1.67316411
130Aplastic anemia (HP:0001915)1.66411909
131Congenital primary aphakia (HP:0007707)1.66377675
132Hyperglycinuria (HP:0003108)1.65726492
133Nephrogenic diabetes insipidus (HP:0009806)1.65153339
134Lethargy (HP:0001254)1.64340896
135Partial duplication of thumb phalanx (HP:0009944)1.62965127
136Flat capital femoral epiphysis (HP:0003370)1.62944598
137Genu varum (HP:0002970)1.62838573
138Increased muscle lipid content (HP:0009058)1.62042339
139Oligodactyly (HP:0012165)1.61659356
140Hypoplastic ischia (HP:0003175)1.60405460
141Cupped ear (HP:0000378)1.59565715
142Pancreatic fibrosis (HP:0100732)1.58612775
143Abnormality of the nasolacrimal system (HP:0000614)1.57959242
144Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.56862101
145Glossoptosis (HP:0000162)1.56601078
146Abnormality of the ischium (HP:0003174)1.54993542
147Fibular hypoplasia (HP:0003038)1.54242299
148Hyperglycinemia (HP:0002154)1.52657794
149Aplasia of the musculature (HP:0100854)1.52257309
150Respiratory distress (HP:0002098)1.51465092
151Decreased lacrimation (HP:0000633)1.50860459
152Abnormality of the clitoris (HP:0000056)1.50400438
153Pheochromocytoma (HP:0002666)1.50373947
154Conical tooth (HP:0000698)1.48961139

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.43994093
2BCR2.98212190
3STK162.94721180
4STK392.88331449
5PBK2.60644265
6CASK2.42467974
7VRK22.31315558
8MKNK12.24821727
9MAP4K22.11710645
10WEE12.01630339
11MST41.98223360
12ACVR1B1.97677384
13OXSR11.92731665
14TRIM281.91281921
15OBSCN1.89535725
16EIF2AK11.79893091
17SRPK11.78030768
18NUAK11.74484306
19EIF2AK31.74409949
20MKNK21.73711845
21FRK1.72484934
22BRSK21.72266985
23BMPR1B1.72171166
24STK38L1.71515065
25TSSK61.59381200
26PLK31.56174100
27CSNK1G31.50437774
28ZAK1.48978366
29DYRK21.44029669
30GRK11.39890571
31DYRK31.38405099
32NME11.35296468
33VRK11.35120444
34PLK41.34848657
35NEK61.34801893
36PLK21.32874063
37LIMK11.31753589
38MAPK131.31483402
39NEK11.24918632
40INSRR1.21487526
41CSNK1G11.19503552
42TNIK1.18853883
43MYLK1.18253926
44AKT31.17698152
45PKN11.11918265
46ERBB41.11112928
47CSNK1G21.08163489
48CCNB11.05931608
49CSNK1A1L1.05592980
50PDK31.02525301
51PDK41.02525301
52PNCK1.01576609
53PDK21.01441672
54NME20.99534179
55WNK40.98877621
56MUSK0.93497531
57MAP2K70.92062821
58CDK30.91662277
59TAF10.88805425
60CDK80.88014127
61CDC70.86945242
62PLK10.86743813
63ERBB30.85871860
64PINK10.85442696
65TTK0.83689461
66PRKCG0.83060077
67PAK30.82654766
68BRSK10.82262522
69ATR0.79272910
70MAPKAPK50.78932209
71STK240.78611581
72MAP3K120.77992935
73MET0.77731374
74CAMK2B0.77172574
75ROCK20.74573105
76CDK190.74424003
77CAMK2D0.73511966
78AURKB0.72755564
79SIK30.72260541
80MELK0.71755601
81MINK10.71130922
82PIK3CA0.70753363
83TLK10.66696106
84MAP3K40.65991984
85CAMK2A0.65246175
86AURKA0.64638949
87ATM0.63364776
88ADRBK20.59987976
89BRAF0.59971957
90YES10.59659215
91EPHA40.59647715
92CDK140.58576461
93CHEK20.56735992
94CDK180.56391049
95EIF2AK20.55726812
96MARK30.55427864
97GRK70.55303091
98CAMK2G0.54023748
99TGFBR10.52963806
100WNK30.51338367
101RPS6KA50.50140424
102EPHB20.49250063
103UHMK10.49246567
104MARK10.48508091
105CDK150.48488902
106CSNK2A10.48369680
107ADRBK10.47842937
108PRKCE0.47673295
109CAMKK20.47074585
110TIE10.46304625
111CSNK2A20.45597036
112CSNK1A10.45455475
113ARAF0.45002925
114STK40.44701512
115PASK0.43166730
116RPS6KA40.43039660
117BCKDK0.42849894
118CSNK1E0.42629712
119CDK11A0.42000373
120FGFR20.40893555
121PRKACA0.40786370
122PRKACB0.40320819
123CSNK1D0.39948235
124SGK2230.39920082
125PRKDC0.36632280
126STK30.33846086
127CHEK10.32550698
128RAF10.30473354
129DYRK1A0.30214101

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.83428177
2Proteasome_Homo sapiens_hsa030503.57482065
3RNA polymerase_Homo sapiens_hsa030203.50029394
4Parkinsons disease_Homo sapiens_hsa050123.33745285
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.29849291
6Huntingtons disease_Homo sapiens_hsa050162.47256373
7Ribosome_Homo sapiens_hsa030102.42246002
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.34270107
9Fatty acid elongation_Homo sapiens_hsa000622.32871465
10Alzheimers disease_Homo sapiens_hsa050102.32747244
11Vitamin B6 metabolism_Homo sapiens_hsa007502.28278431
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.26191494
13Steroid biosynthesis_Homo sapiens_hsa001002.15977081
14Protein export_Homo sapiens_hsa030602.03624688
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.98177410
16Mismatch repair_Homo sapiens_hsa034301.87190245
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.79467189
18Cardiac muscle contraction_Homo sapiens_hsa042601.75960991
19DNA replication_Homo sapiens_hsa030301.73632155
20Nucleotide excision repair_Homo sapiens_hsa034201.73471874
21Pyrimidine metabolism_Homo sapiens_hsa002401.71036335
22Basal transcription factors_Homo sapiens_hsa030221.67230046
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.66051832
24Propanoate metabolism_Homo sapiens_hsa006401.60741813
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59630800
26Spliceosome_Homo sapiens_hsa030401.59306299
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.52404351
28RNA transport_Homo sapiens_hsa030131.52147472
29Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.51029635
30Homologous recombination_Homo sapiens_hsa034401.50630618
31Non-homologous end-joining_Homo sapiens_hsa034501.40665965
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.38339560
33Cell cycle_Homo sapiens_hsa041101.31981832
34Purine metabolism_Homo sapiens_hsa002301.31542342
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.31009806
36Pyruvate metabolism_Homo sapiens_hsa006201.26871231
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.23084661
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.11680166
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.11343725
40Ether lipid metabolism_Homo sapiens_hsa005651.06304746
41RNA degradation_Homo sapiens_hsa030181.05060371
42Butanoate metabolism_Homo sapiens_hsa006501.02107403
43Carbon metabolism_Homo sapiens_hsa012001.00776988
44Sulfur metabolism_Homo sapiens_hsa009200.99606626
45Glutathione metabolism_Homo sapiens_hsa004800.95573678
46Fanconi anemia pathway_Homo sapiens_hsa034600.93440236
47Selenocompound metabolism_Homo sapiens_hsa004500.91728896
48Maturity onset diabetes of the young_Homo sapiens_hsa049500.90538643
49Metabolic pathways_Homo sapiens_hsa011000.89393465
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.88600434
51Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.86414551
52Arginine and proline metabolism_Homo sapiens_hsa003300.86397319
53Base excision repair_Homo sapiens_hsa034100.84830351
54Nitrogen metabolism_Homo sapiens_hsa009100.83721012
55Biosynthesis of amino acids_Homo sapiens_hsa012300.81679738
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.81181530
57Tyrosine metabolism_Homo sapiens_hsa003500.80693941
58Peroxisome_Homo sapiens_hsa041460.78387126
59One carbon pool by folate_Homo sapiens_hsa006700.74632350
60Fatty acid metabolism_Homo sapiens_hsa012120.74530694
61Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.73878336
62Tryptophan metabolism_Homo sapiens_hsa003800.70190412
63Linoleic acid metabolism_Homo sapiens_hsa005910.67992999
64Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65580153
65Phototransduction_Homo sapiens_hsa047440.64297462
66mRNA surveillance pathway_Homo sapiens_hsa030150.63799825
67Folate biosynthesis_Homo sapiens_hsa007900.62896975
68Collecting duct acid secretion_Homo sapiens_hsa049660.61565424
69Cyanoamino acid metabolism_Homo sapiens_hsa004600.58492837
70Primary bile acid biosynthesis_Homo sapiens_hsa001200.57537355
71Arachidonic acid metabolism_Homo sapiens_hsa005900.56816982
72Phenylalanine metabolism_Homo sapiens_hsa003600.55527161
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54202929
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53965686
75Fatty acid degradation_Homo sapiens_hsa000710.52758255
76Nicotine addiction_Homo sapiens_hsa050330.52697207
77Fat digestion and absorption_Homo sapiens_hsa049750.50839518
78Oocyte meiosis_Homo sapiens_hsa041140.48544627
79Taste transduction_Homo sapiens_hsa047420.46607457
80Basal cell carcinoma_Homo sapiens_hsa052170.45766009
81p53 signaling pathway_Homo sapiens_hsa041150.45591609
82Caffeine metabolism_Homo sapiens_hsa002320.45025780
83alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43766355
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43747913
85Vibrio cholerae infection_Homo sapiens_hsa051100.43470918
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43452693
87Sphingolipid metabolism_Homo sapiens_hsa006000.43024587
88Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42291244
89Hedgehog signaling pathway_Homo sapiens_hsa043400.39537949
90Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38896762
91Sulfur relay system_Homo sapiens_hsa041220.38384470
92Fatty acid biosynthesis_Homo sapiens_hsa000610.38106846
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.37806904
94Serotonergic synapse_Homo sapiens_hsa047260.37567924
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.35584184
96Hippo signaling pathway_Homo sapiens_hsa043900.34819538
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34448461
98Tight junction_Homo sapiens_hsa045300.34406012
99beta-Alanine metabolism_Homo sapiens_hsa004100.33591566
100TGF-beta signaling pathway_Homo sapiens_hsa043500.31498258
101Epstein-Barr virus infection_Homo sapiens_hsa051690.31244654
102GABAergic synapse_Homo sapiens_hsa047270.30496796
103N-Glycan biosynthesis_Homo sapiens_hsa005100.29858345
104Systemic lupus erythematosus_Homo sapiens_hsa053220.29260147
105Olfactory transduction_Homo sapiens_hsa047400.29117630
106Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28379934
107Axon guidance_Homo sapiens_hsa043600.27559347
108Alcoholism_Homo sapiens_hsa050340.26652507
109Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.24281344
110Steroid hormone biosynthesis_Homo sapiens_hsa001400.24214318
111Chemical carcinogenesis_Homo sapiens_hsa052040.23945106
112Histidine metabolism_Homo sapiens_hsa003400.23465694
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.22661644
114Retinol metabolism_Homo sapiens_hsa008300.21689185
115Regulation of autophagy_Homo sapiens_hsa041400.21556824
116Dilated cardiomyopathy_Homo sapiens_hsa054140.21048607
117Vitamin digestion and absorption_Homo sapiens_hsa049770.19223973
118Wnt signaling pathway_Homo sapiens_hsa043100.19074765

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