YARS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.17800777
2DNA deamination (GO:0045006)5.15577778
3maturation of SSU-rRNA (GO:0030490)5.00160626
4DNA strand elongation involved in DNA replication (GO:0006271)4.83956077
5folic acid-containing compound biosynthetic process (GO:0009396)4.60405764
6DNA strand elongation (GO:0022616)4.58759246
7telomere maintenance via semi-conservative replication (GO:0032201)4.50729312
8nucleobase biosynthetic process (GO:0046112)4.46167546
9DNA unwinding involved in DNA replication (GO:0006268)4.45899232
10viral transcription (GO:0019083)4.43146737
11translational termination (GO:0006415)4.37008536
12DNA replication initiation (GO:0006270)4.35100464
13formation of translation preinitiation complex (GO:0001731)4.34176501
14purine nucleobase biosynthetic process (GO:0009113)4.23631802
15chaperone-mediated protein transport (GO:0072321)4.14250602
16translational elongation (GO:0006414)4.03940920
17IMP biosynthetic process (GO:0006188)4.00751897
18ribosomal large subunit biogenesis (GO:0042273)3.99075023
19ribosomal small subunit biogenesis (GO:0042274)3.98074168
20ribosome assembly (GO:0042255)3.87210312
21ribonucleoprotein complex biogenesis (GO:0022613)3.85830490
22ribosome biogenesis (GO:0042254)3.84643075
23translational initiation (GO:0006413)3.84532295
24telomere maintenance via recombination (GO:0000722)3.84251387
25establishment of protein localization to mitochondrial membrane (GO:0090151)3.78901849
26SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.78413701
27DNA replication checkpoint (GO:0000076)3.75428505
28folic acid metabolic process (GO:0046655)3.73863637
29positive regulation of chromosome segregation (GO:0051984)3.73328009
30non-recombinational repair (GO:0000726)3.70427967
31double-strand break repair via nonhomologous end joining (GO:0006303)3.70427967
32positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.67457862
33positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.67457862
34positive regulation of mitotic sister chromatid separation (GO:1901970)3.67457862
35cotranslational protein targeting to membrane (GO:0006613)3.67103279
36protein targeting to ER (GO:0045047)3.66570527
37nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65998264
38IMP metabolic process (GO:0046040)3.65612786
39deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.62187686
40mitotic recombination (GO:0006312)3.60030528
41telomere maintenance via telomere lengthening (GO:0010833)3.58907625
42pseudouridine synthesis (GO:0001522)3.57004108
43transcription elongation from RNA polymerase III promoter (GO:0006385)3.56836922
44termination of RNA polymerase III transcription (GO:0006386)3.56836922
45chromatin remodeling at centromere (GO:0031055)3.56339766
46CENP-A containing nucleosome assembly (GO:0034080)3.56237587
47somatic hypermutation of immunoglobulin genes (GO:0016446)3.49135855
48somatic diversification of immune receptors via somatic mutation (GO:0002566)3.49135855
49DNA replication-dependent nucleosome organization (GO:0034723)3.48979425
50DNA replication-dependent nucleosome assembly (GO:0006335)3.48979425
51mitotic nuclear envelope disassembly (GO:0007077)3.48233326
52establishment of protein localization to endoplasmic reticulum (GO:0072599)3.47315116
53protein localization to endoplasmic reticulum (GO:0070972)3.46882393
54rRNA processing (GO:0006364)3.46684137
55protein localization to kinetochore (GO:0034501)3.44497359
56establishment of viral latency (GO:0019043)3.43177853
57regulation of sister chromatid cohesion (GO:0007063)3.41906605
58negative regulation of ligase activity (GO:0051352)3.41245730
59negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.41245730
60spliceosomal snRNP assembly (GO:0000387)3.38950743
61cellular protein complex disassembly (GO:0043624)3.37414027
62glycine metabolic process (GO:0006544)3.36279600
63viral life cycle (GO:0019058)3.35852489
64* mitochondrial RNA metabolic process (GO:0000959)3.35237763
65mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.34616771
66rRNA metabolic process (GO:0016072)3.34612388
67protein targeting to mitochondrion (GO:0006626)3.33456611
68transcription from mitochondrial promoter (GO:0006390)3.32552589
69mitotic metaphase plate congression (GO:0007080)3.31378682
70pteridine-containing compound biosynthetic process (GO:0042559)3.30726154
717-methylguanosine mRNA capping (GO:0006370)3.26504709
72nuclear pore organization (GO:0006999)3.23116310
73nucleotide-excision repair, DNA gap filling (GO:0006297)3.23104928
74tetrahydrofolate metabolic process (GO:0046653)3.22993443
75regulation of helicase activity (GO:0051095)3.21829569
76* translation (GO:0006412)3.20349114
77nuclear envelope disassembly (GO:0051081)3.19891719
78membrane disassembly (GO:0030397)3.19891719
79DNA replication-independent nucleosome organization (GO:0034724)3.18762366
80DNA replication-independent nucleosome assembly (GO:0006336)3.18762366
817-methylguanosine RNA capping (GO:0009452)3.16758449
82RNA capping (GO:0036260)3.16758449
83tRNA methylation (GO:0030488)3.16474896
84proteasome assembly (GO:0043248)3.15969048
85regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.14843140
86cellular component biogenesis (GO:0044085)3.12055873
87DNA damage response, detection of DNA damage (GO:0042769)3.11399782
88mitochondrial respiratory chain complex assembly (GO:0033108)3.10041541
89kinetochore organization (GO:0051383)3.06359275
90mitochondrial respiratory chain complex I assembly (GO:0032981)3.05905134
91NADH dehydrogenase complex assembly (GO:0010257)3.05905134
92mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.05905134
93protein localization to mitochondrion (GO:0070585)3.05064854
94protein localization to chromosome, centromeric region (GO:0071459)3.04745117
95pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.04637858
96establishment of protein localization to mitochondrion (GO:0072655)3.04592172
97regulation of mitochondrial translation (GO:0070129)3.02981334
98protein complex disassembly (GO:0043241)3.00118432
99telomere organization (GO:0032200)2.98555726
100serine family amino acid biosynthetic process (GO:0009070)2.98508234
101nuclear-transcribed mRNA catabolic process (GO:0000956)2.97930383
102establishment of integrated proviral latency (GO:0075713)2.97814652
103prenylation (GO:0097354)2.97330232
104protein prenylation (GO:0018342)2.97330232
105telomere maintenance (GO:0000723)2.96214766
106negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.95755190
107protein complex biogenesis (GO:0070271)2.93518556
108deoxyribonucleotide biosynthetic process (GO:0009263)2.93250943
109maturation of 5.8S rRNA (GO:0000460)2.93211095
110regulation of mitotic metaphase/anaphase transition (GO:0030071)2.93011272
111regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.93011272
112tRNA modification (GO:0006400)2.90859831
113ncRNA processing (GO:0034470)2.90761882
114nuclear pore complex assembly (GO:0051292)2.90406959
115regulation of cellular amino acid metabolic process (GO:0006521)2.90307339
116L-serine metabolic process (GO:0006563)2.89926448
117kinetochore assembly (GO:0051382)2.89881944
118mitotic sister chromatid segregation (GO:0000070)2.89713619
119metaphase plate congression (GO:0051310)2.88787665
120spliceosomal complex assembly (GO:0000245)2.88760107
121folic acid-containing compound metabolic process (GO:0006760)2.88310273
122positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.87730582
123* ncRNA metabolic process (GO:0034660)2.86584177
124anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.86472745
125macromolecular complex disassembly (GO:0032984)2.86136852
126regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.84987372
127regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.84950259
128pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.84200680
129histone exchange (GO:0043486)2.82931488
130positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.82915989
131nucleobase-containing small molecule interconversion (GO:0015949)2.81210783
132transcription-coupled nucleotide-excision repair (GO:0006283)2.80640452
133DNA duplex unwinding (GO:0032508)2.80598610
134deoxyribose phosphate biosynthetic process (GO:0046385)2.80226247
1352-deoxyribonucleotide biosynthetic process (GO:0009265)2.80226247
136negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.80186942
137* tRNA aminoacylation for protein translation (GO:0006418)2.79763201
138mRNA catabolic process (GO:0006402)2.79695475
139RNA catabolic process (GO:0006401)2.79409817
140cell cycle G1/S phase transition (GO:0044843)2.77729796
141G1/S transition of mitotic cell cycle (GO:0000082)2.77729796
142oxidative phosphorylation (GO:0006119)2.75803520
143DNA geometric change (GO:0032392)2.75782522
144* tRNA aminoacylation (GO:0043039)2.75538910
145* amino acid activation (GO:0043038)2.75538910
146rRNA modification (GO:0000154)2.73445360
147pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.73369388

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.73847033
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.68483443
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.23786725
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.34630982
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.25153218
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.14491329
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.04214823
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.02828374
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.93674934
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.88697536
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.87224397
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.85316563
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.79510385
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.71438582
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.59509364
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.53676128
17XRN2_22483619_ChIP-Seq_HELA_Human2.43040844
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.39337557
19VDR_23849224_ChIP-Seq_CD4+_Human2.17691092
20* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17214293
21E2F1_18555785_ChIP-Seq_MESCs_Mouse2.16627541
22DCP1A_22483619_ChIP-Seq_HELA_Human2.05958096
23AR_21909140_ChIP-Seq_LNCAP_Human2.03879907
24ELF1_17652178_ChIP-ChIP_JURKAT_Human1.99719477
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.96615437
26FOXP3_21729870_ChIP-Seq_TREG_Human1.95755217
27GABP_19822575_ChIP-Seq_HepG2_Human1.89237517
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.85818799
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.85026971
30* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84727250
31MYCN_18555785_ChIP-Seq_MESCs_Mouse1.83178869
32TTF2_22483619_ChIP-Seq_HELA_Human1.79925744
33* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79094886
34* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.76196282
35SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.75358224
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74633882
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.73334974
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71257512
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.70061809
40EGR1_19374776_ChIP-ChIP_THP-1_Human1.67337369
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.61466372
42MYC_22102868_ChIP-Seq_BL_Human1.58394189
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58132776
44SRF_21415370_ChIP-Seq_HL-1_Mouse1.56495458
45MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.56374609
46* YY1_21170310_ChIP-Seq_MESCs_Mouse1.48164968
47CIITA_25753668_ChIP-Seq_RAJI_Human1.47240393
48ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.45874616
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.45569686
50ELK1_19687146_ChIP-ChIP_HELA_Human1.45566644
51* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44543224
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.44413431
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.41524507
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.40840412
55* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39822988
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.39282511
57ZNF263_19887448_ChIP-Seq_K562_Human1.39015121
58KDM5A_27292631_Chip-Seq_BREAST_Human1.36335703
59FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.35471784
60* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34463776
61CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.33800043
62* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.27136957
63POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26838004
64PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.25014185
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21427176
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21147694
67CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20809434
68KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20526360
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.20443510
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.19803711
71POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19135976
72* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.18530607
73CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.15102353
74* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.14923479
75FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.13883897
76* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11876854
77IRF1_19129219_ChIP-ChIP_H3396_Human1.10359517
78PADI4_21655091_ChIP-ChIP_MCF-7_Human1.09011799
79* TFEB_21752829_ChIP-Seq_HELA_Human1.08585770
80VDR_21846776_ChIP-Seq_THP-1_Human1.08018862
81SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.03607234
82ELK1_22589737_ChIP-Seq_MCF10A_Human1.03159881
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.02790813
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02549710
85NANOG_16153702_ChIP-ChIP_HESCs_Human1.01900480
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00739782
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.99912379
88MYC_18940864_ChIP-ChIP_HL60_Human0.98998532
89RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98865283
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96621719
91CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94068428
92HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93099826
93ESR1_15608294_ChIP-ChIP_MCF-7_Human0.92974890
94HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.92529495
95SOX2_16153702_ChIP-ChIP_HESCs_Human0.91958868
96TP63_19390658_ChIP-ChIP_HaCaT_Human0.91881010
97SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91303463
98SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91224684
99SOX17_20123909_ChIP-Seq_XEN_Mouse0.91209329
100HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86855912
101KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.86212324
102SPI1_23547873_ChIP-Seq_NB4_Human0.85563171
103SOX2_18555785_ChIP-Seq_MESCs_Mouse0.85414052
104* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.85370052
105KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.83241169
106KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.83241169
107KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.83241169
108SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.83022090
109POU5F1_16153702_ChIP-ChIP_HESCs_Human0.82580859
110* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82451140
111ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.81437927
112CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.80833744
113CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80263996
114OCT4_18692474_ChIP-Seq_MEFs_Mouse0.79948249
115PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75714490
116* SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.74854534

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.21361992
2MP0004957_abnormal_blastocyst_morpholog4.56447597
3MP0010094_abnormal_chromosome_stability4.11466414
4MP0003111_abnormal_nucleus_morphology4.01563086
5MP0003806_abnormal_nucleotide_metabolis3.71596804
6MP0003077_abnormal_cell_cycle3.62042351
7MP0008057_abnormal_DNA_replication3.40244008
8MP0008058_abnormal_DNA_repair2.98634816
9MP0008932_abnormal_embryonic_tissue2.62545127
10MP0008007_abnormal_cellular_replicative2.58083817
11MP0002396_abnormal_hematopoietic_system2.57845856
12MP0006292_abnormal_olfactory_placode2.41640586
13MP0010352_gastrointestinal_tract_polyps2.36993580
14MP0001730_embryonic_growth_arrest2.26847466
15MP0003123_paternal_imprinting2.11457892
16MP0000350_abnormal_cell_proliferation2.08956659
17MP0000490_abnormal_crypts_of2.03568316
18MP0010030_abnormal_orbit_morphology2.01545784
19MP0006054_spinal_hemorrhage1.93799098
20MP0006036_abnormal_mitochondrial_physio1.90873783
21MP0005360_urolithiasis1.90225905
22MP0003186_abnormal_redox_activity1.88215107
23MP0002139_abnormal_hepatobiliary_system1.85869311
24MP0005085_abnormal_gallbladder_physiolo1.78638993
25MP0008789_abnormal_olfactory_epithelium1.63522605
26MP0003315_abnormal_perineum_morphology1.63252300
27MP0003786_premature_aging1.60768508
28MP0001697_abnormal_embryo_size1.59299343
29MP0006035_abnormal_mitochondrial_morpho1.56413478
30MP0005380_embryogenesis_phenotype1.55328177
31MP0001672_abnormal_embryogenesis/_devel1.55328177
32MP0002080_prenatal_lethality1.51303079
33MP0005501_abnormal_skin_physiology1.50668368
34MP0000566_synostosis1.49655184
35MP0003984_embryonic_growth_retardation1.49526378
36MP0003937_abnormal_limbs/digits/tail_de1.49239171
37MP0002088_abnormal_embryonic_growth/wei1.45810633
38MP0002019_abnormal_tumor_incidence1.43701216
39MP0005365_abnormal_bile_salt1.41366811
40MP0000313_abnormal_cell_death1.39979098
41MP0003656_abnormal_erythrocyte_physiolo1.38998373
42MP0003567_abnormal_fetal_cardiomyocyte1.36645163
43MP0009697_abnormal_copulation1.36471568
44MP0001853_heart_inflammation1.33665036
45MP0002086_abnormal_extraembryonic_tissu1.32755508
46MP0005499_abnormal_olfactory_system1.32173003
47MP0005394_taste/olfaction_phenotype1.32173003
48MP0000358_abnormal_cell_content/1.31214244
49MP0002234_abnormal_pharynx_morphology1.30280575
50MP0001293_anophthalmia1.28794580
51MP0001529_abnormal_vocalization1.28265776
52MP0005397_hematopoietic_system_phenotyp1.28001017
53MP0001545_abnormal_hematopoietic_system1.28001017
54MP0004808_abnormal_hematopoietic_stem1.23095470
55MP0010307_abnormal_tumor_latency1.21644382
56MP0002163_abnormal_gland_morphology1.17578974
57MP0003718_maternal_effect1.17574905
58MP0002160_abnormal_reproductive_system1.16214710
59MP0005389_reproductive_system_phenotype1.14750844
60MP0002084_abnormal_developmental_patter1.14638896
61MP0009333_abnormal_splenocyte_physiolog1.14370392
62MP0002938_white_spotting1.13543643
63MP0002697_abnormal_eye_size1.12668237
64MP0002085_abnormal_embryonic_tissue1.12596599
65MP0005266_abnormal_metabolism1.12590993
66MP0001919_abnormal_reproductive_system1.09546038
67MP0004197_abnormal_fetal_growth/weight/1.09394405
68MP0001764_abnormal_homeostasis1.07723786
69MP0001286_abnormal_eye_development1.07127147
70MP0001929_abnormal_gametogenesis1.06549651
71MP0003763_abnormal_thymus_physiology1.04689122
72MP0004147_increased_porphyrin_level1.04472440
73MP0002751_abnormal_autonomic_nervous1.04155567
74MP0002722_abnormal_immune_system1.03738141
75MP0006072_abnormal_retinal_apoptosis1.03062948
76MP0003221_abnormal_cardiomyocyte_apopto1.02562789
77MP0000689_abnormal_spleen_morphology0.99554733
78MP0005395_other_phenotype0.99297540
79MP0000049_abnormal_middle_ear0.99182663
80MP0000467_abnormal_esophagus_morphology0.97674432
81MP0002398_abnormal_bone_marrow0.97579148
82MP0000703_abnormal_thymus_morphology0.94370523
83MP0000653_abnormal_sex_gland0.94359076
84MP0000858_altered_metastatic_potential0.94272181
85MP0001661_extended_life_span0.91604546
86MP0000598_abnormal_liver_morphology0.90382492
87MP0008877_abnormal_DNA_methylation0.90011491
88MP0008995_early_reproductive_senescence0.88585792
89MP0005220_abnormal_exocrine_pancreas0.88583729
90MP0003705_abnormal_hypodermis_morpholog0.88252029
91MP0005319_abnormal_enzyme/_coenzyme0.88005778
92MP0009379_abnormal_foot_pigmentation0.86321501
93MP0002233_abnormal_nose_morphology0.85939167
94MP0005332_abnormal_amino_acid0.84964702
95MP0001119_abnormal_female_reproductive0.84084186
96MP0002429_abnormal_blood_cell0.83328238
97MP0001881_abnormal_mammary_gland0.83254236
98MP0009053_abnormal_anal_canal0.83219818
99MP0000685_abnormal_immune_system0.80963904
100MP0003119_abnormal_digestive_system0.80255576
101MP0001346_abnormal_lacrimal_gland0.80178036
102MP0005083_abnormal_biliary_tract0.79287323
103MP0000609_abnormal_liver_physiology0.79040471
104MP0002269_muscular_atrophy0.78992894
105MP0002102_abnormal_ear_morphology0.78820466
106MP0003890_abnormal_embryonic-extraembry0.78470293
107MP0009840_abnormal_foam_cell0.77907852
108MP0004133_heterotaxia0.76968396
109MP0002132_abnormal_respiratory_system0.74663077
110MP0002796_impaired_skin_barrier0.74098583
111MP0000762_abnormal_tongue_morphology0.72274473
112MP0009672_abnormal_birth_weight0.70850928
113MP0000428_abnormal_craniofacial_morphol0.70463736
114MP0002254_reproductive_system_inflammat0.70146222
115MP0000477_abnormal_intestine_morphology0.67898690
116MP0001145_abnormal_male_reproductive0.67580570
117MP0008875_abnormal_xenobiotic_pharmacok0.67221653
118MP0002092_abnormal_eye_morphology0.67044084
119MP0005384_cellular_phenotype0.66735894
120MP0005023_abnormal_wound_healing0.66466893
121MP0002177_abnormal_outer_ear0.65910323
122MP0005197_abnormal_uvea_morphology0.65452109
123MP0002161_abnormal_fertility/fecundity0.63924425
124MP0003699_abnormal_female_reproductive0.63704000
125MP0001915_intracranial_hemorrhage0.62639281
126MP0001188_hyperpigmentation0.62066686
127MP0001727_abnormal_embryo_implantation0.61986517
128MP0005391_vision/eye_phenotype0.61780292
129MP0001666_abnormal_nutrient_absorption0.61048113
130MP0005376_homeostasis/metabolism_phenot0.59920595
131MP0000716_abnormal_immune_system0.59806534
132MP0000537_abnormal_urethra_morphology0.59777426
133MP0005076_abnormal_cell_differentiation0.59759585
134MP0003115_abnormal_respiratory_system0.59393331
135MP0002210_abnormal_sex_determination0.59271069
136MP0005075_abnormal_melanosome_morpholog0.58381262
137MP0004264_abnormal_extraembryonic_tissu0.58216606
138MP0004233_abnormal_muscle_weight0.57780781
139MP0000627_abnormal_mammary_gland0.56285156
140MP0003941_abnormal_skin_development0.55345828
141MP0000371_diluted_coat_color0.54978562
142MP0001873_stomach_inflammation0.54617967
143MP0008770_decreased_survivor_rate0.54021034
144MP0002111_abnormal_tail_morphology0.53559020
145MP0002089_abnormal_postnatal_growth/wei0.53129107
146MP0009703_decreased_birth_body0.52217740
147MP0010329_abnormal_lipoprotein_level0.51658308
148MP0003121_genomic_imprinting0.50102166

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.29305606
2Abnormal number of erythroid precursors (HP:0012131)5.08825852
3Reticulocytopenia (HP:0001896)4.56603534
4Oral leukoplakia (HP:0002745)4.00321158
5Birth length less than 3rd percentile (HP:0003561)3.91844433
6Aplastic anemia (HP:0001915)3.57393796
7Macrocytic anemia (HP:0001972)3.27198568
8Hepatic necrosis (HP:0002605)3.12509336
9Pallor (HP:0000980)3.09914899
10Duplicated collecting system (HP:0000081)3.08831440
11Selective tooth agenesis (HP:0001592)3.07024346
12Hepatocellular necrosis (HP:0001404)3.03503472
13Multiple enchondromatosis (HP:0005701)3.01552065
14Microretrognathia (HP:0000308)3.00291322
15Abnormality of pyrimidine metabolism (HP:0004353)2.96039163
16Colon cancer (HP:0003003)2.95840919
17Decreased activity of mitochondrial respiratory chain (HP:0008972)2.87803894
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.87803894
19* Increased serum lactate (HP:0002151)2.87748176
20Abnormality of the heme biosynthetic pathway (HP:0010472)2.83254868
21Hypobetalipoproteinemia (HP:0003563)2.78739531
2211 pairs of ribs (HP:0000878)2.77867123
23Abnormality of the renal collecting system (HP:0004742)2.76496144
24Increased CSF lactate (HP:0002490)2.72033218
25Agnosia (HP:0010524)2.71513699
26Abnormality of the anterior horn cell (HP:0006802)2.70284170
27Degeneration of anterior horn cells (HP:0002398)2.70284170
28Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.69923110
29Progressive macrocephaly (HP:0004481)2.68269407
30Rough bone trabeculation (HP:0100670)2.64723838
31Thrombocytosis (HP:0001894)2.63354209
32Abnormality of reticulocytes (HP:0004312)2.57113702
33Ragged-red muscle fibers (HP:0003200)2.55668309
34Trismus (HP:0000211)2.55358945
35Aplasia/Hypoplasia of the sacrum (HP:0008517)2.53707211
36Absent thumb (HP:0009777)2.47438830
37Abnormal mitochondria in muscle tissue (HP:0008316)2.46873352
38Hypoplastic pelvis (HP:0008839)2.46357933
39Breast hypoplasia (HP:0003187)2.46205515
40Microvesicular hepatic steatosis (HP:0001414)2.46109680
41Spastic diplegia (HP:0001264)2.42343567
42Megaloblastic anemia (HP:0001889)2.41611727
43Mitochondrial inheritance (HP:0001427)2.40684484
44Abnormality of chromosome stability (HP:0003220)2.39917446
45Abnormality of alanine metabolism (HP:0010916)2.39893667
46Hyperalaninemia (HP:0003348)2.39893667
47Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.39893667
48Chromsome breakage (HP:0040012)2.38916378
49Abnormal lung lobation (HP:0002101)2.38612532
503-Methylglutaconic aciduria (HP:0003535)2.38398715
51* Lactic acidosis (HP:0003128)2.37417747
52Abnormal protein glycosylation (HP:0012346)2.35527930
53Abnormal glycosylation (HP:0012345)2.35527930
54Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.35527930
55Abnormal protein N-linked glycosylation (HP:0012347)2.35527930
56Hyperglycinemia (HP:0002154)2.35380415
57Cerebral edema (HP:0002181)2.34056931
58Abnormality of the preputium (HP:0100587)2.34055615
59Abnormality of methionine metabolism (HP:0010901)2.33327693
60Renal Fanconi syndrome (HP:0001994)2.33225950
61Abnormality of glycolysis (HP:0004366)2.32679505
62Increased serum pyruvate (HP:0003542)2.32679505
63Acute necrotizing encephalopathy (HP:0006965)2.32468506
64Pancytopenia (HP:0001876)2.31669482
65Ependymoma (HP:0002888)2.30561361
66Acute encephalopathy (HP:0006846)2.29910149
67Small intestinal stenosis (HP:0012848)2.28237506
68Duodenal stenosis (HP:0100867)2.28237506
69Long foot (HP:0001833)2.27985678
70Horseshoe kidney (HP:0000085)2.27347358
71Myelodysplasia (HP:0002863)2.23066617
72Lipid accumulation in hepatocytes (HP:0006561)2.22783443
73Dry hair (HP:0011359)2.21955702
74Abnormality of serum amino acid levels (HP:0003112)2.21831350
75Hyperammonemia (HP:0001987)2.21646358
76Type I transferrin isoform profile (HP:0003642)2.19291540
77Delayed CNS myelination (HP:0002188)2.18270742
78Abnormality of the labia minora (HP:0012880)2.17676779
79Meckel diverticulum (HP:0002245)2.15788488
80Increased intramyocellular lipid droplets (HP:0012240)2.13574067
81Increased hepatocellular lipid droplets (HP:0006565)2.12868659
82Dicarboxylic aciduria (HP:0003215)2.12051335
83Abnormality of dicarboxylic acid metabolism (HP:0010995)2.12051335
84Abnormality of the ileum (HP:0001549)2.11298333
85Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.11195191
86Respiratory failure (HP:0002878)2.09966581
87Abnormality of monocarboxylic acid metabolism (HP:0010996)2.09565401
88Premature graying of hair (HP:0002216)2.07808083
89Carpal bone hypoplasia (HP:0001498)2.06037769
90Increased muscle lipid content (HP:0009058)2.05777721
91Facial cleft (HP:0002006)2.04612795
92Ureteral duplication (HP:0000073)2.03084580
93Rhabdomyolysis (HP:0003201)2.01902224
94CNS demyelination (HP:0007305)2.00968135
95Neoplasm of the pancreas (HP:0002894)2.00681960
96Absent forearm bone (HP:0003953)2.00669229
97Aplasia involving forearm bones (HP:0009822)2.00669229
98Nausea (HP:0002018)1.98740853
99Respiratory difficulties (HP:0002880)1.98306388
100Increased serum ferritin (HP:0003281)1.98150440
101Chromosomal breakage induced by crosslinking agents (HP:0003221)1.97652212
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.96431558
103Premature ovarian failure (HP:0008209)1.96085368
104Cerebral hypomyelination (HP:0006808)1.93242793
105Bone marrow hypocellularity (HP:0005528)1.92800445
106Absent radius (HP:0003974)1.92456487
107Hypoglycemic coma (HP:0001325)1.92333745
108Angiofibromas (HP:0010615)1.92301306
109Adenoma sebaceum (HP:0009720)1.92301306
110Abnormality of the duodenum (HP:0002246)1.91394348
111Clubbing of toes (HP:0100760)1.91004875
112Cellular immunodeficiency (HP:0005374)1.90283012
113Abnormal number of incisors (HP:0011064)1.89684083
114* Progressive muscle weakness (HP:0003323)1.89149384
115Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.89100217
116Emotional lability (HP:0000712)1.88409563
117* Exercise intolerance (HP:0003546)1.87071097
118Abnormality of serine family amino acid metabolism (HP:0010894)1.86862602
119Abnormality of glycine metabolism (HP:0010895)1.86862602
120Squamous cell carcinoma (HP:0002860)1.86850225
121Glossoptosis (HP:0000162)1.86503755
122Rhabdomyosarcoma (HP:0002859)1.85998981
123Basal cell carcinoma (HP:0002671)1.85704679
124Abnormality of iron homeostasis (HP:0011031)1.84207390
125Missing ribs (HP:0000921)1.83558628
126Medulloblastoma (HP:0002885)1.83362780
127Hypoplasia of the radius (HP:0002984)1.82508307
128Reduced antithrombin III activity (HP:0001976)1.81667680
129Triphalangeal thumb (HP:0001199)1.81392201
130Sparse eyelashes (HP:0000653)1.79715866
131Cleft eyelid (HP:0000625)1.79547915
132Glioma (HP:0009733)1.79523790
133Sloping forehead (HP:0000340)1.74941273
134Lethargy (HP:0001254)1.74181131
135Abnormal trabecular bone morphology (HP:0100671)1.72310644
136Acute lymphatic leukemia (HP:0006721)1.72076708
137Hypoplasia of the pons (HP:0012110)1.70267856
138Abnormality of the carotid arteries (HP:0005344)1.68046458
139Shoulder girdle muscle weakness (HP:0003547)1.67439466
140Abnormality of the umbilical cord (HP:0010881)1.67231238

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.69263878
2VRK23.95002421
3WEE13.78423215
4EIF2AK13.70132937
5PBK3.53687859
6NME23.28624082
7CDC73.27662312
8ACVR1B3.08194057
9EIF2AK32.62620562
10STK162.49711575
11BCKDK2.34947663
12NEK22.33523679
13NEK12.29552638
14TSSK62.05964833
15TTK2.04737172
16SCYL21.91330179
17VRK11.78167928
18DYRK31.75813804
19TLK11.67268501
20PLK11.66487692
21BRSK21.65979594
22RPS6KB21.65019026
23FLT31.63160704
24PKN21.57312881
25RPS6KA41.55099205
26AURKB1.50510467
27SRPK11.46682602
28CDK71.43516925
29CDK81.42113343
30TGFBR11.40863361
31ATR1.39614172
32CCNB11.37169298
33CDK41.36396802
34MAP3K101.34850899
35TRIM281.34468975
36PASK1.30956095
37NUAK11.24372835
38PIM21.24179574
39KDR1.22040465
40TESK21.21884446
41BRSK11.20696236
42AURKA1.15815971
43LRRK21.13615545
44MAP3K81.13182692
45PLK41.06944990
46CHEK21.01623945
47PLK31.01535352
48TAF11.00743808
49CDK120.99059633
50EPHA20.96920636
51TAOK10.92821286
52STK100.92526968
53CHEK10.89763093
54MAP4K20.89339943
55PDK20.88728960
56CSNK1G30.87037870
57TIE10.86886207
58PIM10.86508133
59MAPKAPK30.86167299
60PAK40.85520535
61MKNK10.82335509
62EEF2K0.79775606
63ERN10.78914570
64CSNK1G10.78600749
65MAP2K30.75223642
66CSNK1A1L0.73116572
67STK40.72196652
68MELK0.71387407
69ERBB40.70547881
70ZAK0.69673927
71DYRK20.68866736
72BMPR1B0.67098640
73ARAF0.66699241
74MAP4K10.66279390
75CSNK2A20.65532904
76MAP2K70.62500335
77EIF2AK20.60318221
78CSNK2A10.60314751
79MAP3K110.60225481
80FGFR10.59507173
81NME10.59111156
82ATM0.58840776
83CSNK1G20.58608422
84CDK20.58437056
85WNK30.56793881
86AKT20.56582721
87MAP3K120.56572765
88GRK60.56420899
89BRAF0.55844649
90RAF10.55506862
91TEC0.55154306
92BTK0.55145468
93LIMK10.55036678
94STK240.53509479
95TRIB30.52302157
96ABL20.52220477
97ILK0.51641602
98TESK10.50466416
99DAPK10.48670932
100PRKCI0.47387574
101CDK60.46986355
102SMG10.45734091
103ALK0.44517916
104TYK20.43614283
105PAK10.41974095
106ZAP700.41171205
107PDK40.41029258
108PDK30.41029258
109MARK30.40081008
110BRD40.40026630
111CDK190.39272518
112MUSK0.39237860
113BCR0.38580037
114RPS6KA50.36959905
115TAOK20.34944342
116STK30.34249438
117MST40.34087722
118NEK90.33388049
119CDK10.32853582
120JAK30.32568707
121STK38L0.32228921
122MAP3K30.31357899
123MST1R0.30848078
124CDK90.29922280
125MKNK20.29750510
126TNIK0.29328930
127FGFR30.27366294
128IRAK30.26396663
129MAPK110.26057114
130MAP3K50.25679318
131BLK0.25526112

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.75461878
2Mismatch repair_Homo sapiens_hsa034303.77613769
3Ribosome_Homo sapiens_hsa030103.76023014
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.20787422
5One carbon pool by folate_Homo sapiens_hsa006703.04619804
6Proteasome_Homo sapiens_hsa030503.04546515
7Spliceosome_Homo sapiens_hsa030402.70883423
8Base excision repair_Homo sapiens_hsa034102.68057521
9RNA polymerase_Homo sapiens_hsa030202.62023910
10RNA transport_Homo sapiens_hsa030132.57685545
11Nucleotide excision repair_Homo sapiens_hsa034202.49907865
12Pyrimidine metabolism_Homo sapiens_hsa002402.42384438
13Homologous recombination_Homo sapiens_hsa034402.42091074
14* Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.39714976
15Cell cycle_Homo sapiens_hsa041101.99511404
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.77882724
17Non-homologous end-joining_Homo sapiens_hsa034501.67637785
18Cysteine and methionine metabolism_Homo sapiens_hsa002701.67040474
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.66621337
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.64355968
21Biosynthesis of amino acids_Homo sapiens_hsa012301.59865739
22Selenocompound metabolism_Homo sapiens_hsa004501.59499377
23RNA degradation_Homo sapiens_hsa030181.56749181
24Fatty acid elongation_Homo sapiens_hsa000621.55049949
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.51686053
26Folate biosynthesis_Homo sapiens_hsa007901.47894269
27Fanconi anemia pathway_Homo sapiens_hsa034601.45750882
28Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.43046610
29Carbon metabolism_Homo sapiens_hsa012001.38928657
30Sulfur relay system_Homo sapiens_hsa041221.37338180
31Drug metabolism - other enzymes_Homo sapiens_hsa009831.35682906
32Steroid biosynthesis_Homo sapiens_hsa001001.26030862
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26005244
34Cyanoamino acid metabolism_Homo sapiens_hsa004601.25228849
35Basal transcription factors_Homo sapiens_hsa030221.23926217
36Pentose phosphate pathway_Homo sapiens_hsa000301.15006492
37Purine metabolism_Homo sapiens_hsa002301.14880943
38Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.12187831
39Systemic lupus erythematosus_Homo sapiens_hsa053221.11758391
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.08420063
41Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.08339308
42p53 signaling pathway_Homo sapiens_hsa041151.07991267
43mRNA surveillance pathway_Homo sapiens_hsa030151.05714498
44Parkinsons disease_Homo sapiens_hsa050121.00824282
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91875660
46Pyruvate metabolism_Homo sapiens_hsa006200.88671075
47Glutathione metabolism_Homo sapiens_hsa004800.87691523
48Primary bile acid biosynthesis_Homo sapiens_hsa001200.87320746
49Propanoate metabolism_Homo sapiens_hsa006400.85572291
50Oxidative phosphorylation_Homo sapiens_hsa001900.80062378
51Vitamin B6 metabolism_Homo sapiens_hsa007500.80035293
52Huntingtons disease_Homo sapiens_hsa050160.78659131
53Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78526776
54Protein export_Homo sapiens_hsa030600.78266908
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.76909504
56Antigen processing and presentation_Homo sapiens_hsa046120.72939914
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.72653363
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71719775
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69252259
60Fatty acid degradation_Homo sapiens_hsa000710.67497166
61Epstein-Barr virus infection_Homo sapiens_hsa051690.67061040
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61076256
63N-Glycan biosynthesis_Homo sapiens_hsa005100.58845890
64Arginine and proline metabolism_Homo sapiens_hsa003300.57387041
65Viral carcinogenesis_Homo sapiens_hsa052030.56448740
66beta-Alanine metabolism_Homo sapiens_hsa004100.56125715
67Cardiac muscle contraction_Homo sapiens_hsa042600.54742513
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54703802
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.54265606
70Metabolic pathways_Homo sapiens_hsa011000.53096530
71Herpes simplex infection_Homo sapiens_hsa051680.53059251
72Phenylalanine metabolism_Homo sapiens_hsa003600.52874855
73Sulfur metabolism_Homo sapiens_hsa009200.50954995
74Arginine biosynthesis_Homo sapiens_hsa002200.50383069
75Legionellosis_Homo sapiens_hsa051340.50313769
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49906618
77Peroxisome_Homo sapiens_hsa041460.48955635
78Tryptophan metabolism_Homo sapiens_hsa003800.45629822
79Oocyte meiosis_Homo sapiens_hsa041140.42902293
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42611631
81HTLV-I infection_Homo sapiens_hsa051660.42388144
82Galactose metabolism_Homo sapiens_hsa000520.41490817
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.41382359
84Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39894577
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39196338
86Fructose and mannose metabolism_Homo sapiens_hsa000510.36363315
87Central carbon metabolism in cancer_Homo sapiens_hsa052300.35644150
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.35626614
89Tyrosine metabolism_Homo sapiens_hsa003500.33851732
90Alzheimers disease_Homo sapiens_hsa050100.33768799
91Butanoate metabolism_Homo sapiens_hsa006500.32711708
92Chemical carcinogenesis_Homo sapiens_hsa052040.31840646
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31185263
94Thyroid cancer_Homo sapiens_hsa052160.30795827
95Caffeine metabolism_Homo sapiens_hsa002320.29553950
96Lysine degradation_Homo sapiens_hsa003100.26765589
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26432772
98Bladder cancer_Homo sapiens_hsa052190.25286393
99Vitamin digestion and absorption_Homo sapiens_hsa049770.24316975
100Fatty acid metabolism_Homo sapiens_hsa012120.23690685
101Fat digestion and absorption_Homo sapiens_hsa049750.22449485
102Apoptosis_Homo sapiens_hsa042100.22218306
103TGF-beta signaling pathway_Homo sapiens_hsa043500.20760424
104Small cell lung cancer_Homo sapiens_hsa052220.19229451
105Starch and sucrose metabolism_Homo sapiens_hsa005000.18290754
106Phototransduction_Homo sapiens_hsa047440.17176325
107Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16632506
108Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.14338418
109Hippo signaling pathway_Homo sapiens_hsa043900.14309322
110Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.13510661
111Basal cell carcinoma_Homo sapiens_hsa052170.13108434
112Retinol metabolism_Homo sapiens_hsa008300.11745454
113Renin-angiotensin system_Homo sapiens_hsa046140.11565071
114Alcoholism_Homo sapiens_hsa050340.10231632
115Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.09913834
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.09606462
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.05130891
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.03918925
119Hedgehog signaling pathway_Homo sapiens_hsa043400.03558911
120Vibrio cholerae infection_Homo sapiens_hsa051100.00511560

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »