YBX1P10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of protein localization to mitochondrial membrane (GO:0090151)6.74288157
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.66191099
3ATP synthesis coupled proton transport (GO:0015986)6.25646871
4energy coupled proton transport, down electrochemical gradient (GO:0015985)6.25646871
5ribosomal small subunit assembly (GO:0000028)5.96952955
6viral transcription (GO:0019083)5.53850861
7mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.49785176
8translational termination (GO:0006415)5.43295983
9maturation of SSU-rRNA (GO:0030490)5.42587825
10respiratory electron transport chain (GO:0022904)5.22130123
11electron transport chain (GO:0022900)5.12558459
12chaperone-mediated protein transport (GO:0072321)5.05793568
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.79230209
14cotranslational protein targeting to membrane (GO:0006613)4.76217704
15protein targeting to ER (GO:0045047)4.73844093
16translational elongation (GO:0006414)4.73460018
17protein neddylation (GO:0045116)4.61357598
18proteasome assembly (GO:0043248)4.56857730
19DNA deamination (GO:0045006)4.55905372
20establishment of protein localization to endoplasmic reticulum (GO:0072599)4.54492580
21protein localization to endoplasmic reticulum (GO:0070972)4.41016174
22ribosomal small subunit biogenesis (GO:0042274)4.40476131
23protein complex biogenesis (GO:0070271)4.30454754
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.19541787
25mitochondrial respiratory chain complex I assembly (GO:0032981)4.19541787
26NADH dehydrogenase complex assembly (GO:0010257)4.19541787
27viral life cycle (GO:0019058)4.16111395
28nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.14177789
29nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.12414492
30cellular protein complex disassembly (GO:0043624)4.11603586
31mitochondrial respiratory chain complex assembly (GO:0033108)4.08953113
32behavioral response to nicotine (GO:0035095)4.08557581
33exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.05418283
34translational initiation (GO:0006413)3.97478726
35translation (GO:0006412)3.95886336
36chromatin remodeling at centromere (GO:0031055)3.77678993
37ribosomal large subunit biogenesis (GO:0042273)3.73053610
38protein-cofactor linkage (GO:0018065)3.70636514
39CENP-A containing nucleosome assembly (GO:0034080)3.65194801
40respiratory chain complex IV assembly (GO:0008535)3.63220755
41DNA damage response, detection of DNA damage (GO:0042769)3.55109783
42protein complex disassembly (GO:0043241)3.50785800
43hydrogen ion transmembrane transport (GO:1902600)3.47847804
44macromolecular complex disassembly (GO:0032984)3.42425754
45ATP biosynthetic process (GO:0006754)3.41065980
46transcription elongation from RNA polymerase III promoter (GO:0006385)3.38852546
47termination of RNA polymerase III transcription (GO:0006386)3.38852546
48pseudouridine synthesis (GO:0001522)3.36147814
49regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.32590284
50tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.30019179
51RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.30019179
52cytochrome complex assembly (GO:0017004)3.28213622
53nuclear-transcribed mRNA catabolic process (GO:0000956)3.20373728
54rRNA modification (GO:0000154)3.20359570
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.18625985
56rRNA processing (GO:0006364)3.16885906
57cellular component biogenesis (GO:0044085)3.16240307
58proton transport (GO:0015992)3.16080122
59water-soluble vitamin biosynthetic process (GO:0042364)3.14203558
60ribonucleoprotein complex biogenesis (GO:0022613)3.13850574
61purine nucleoside triphosphate biosynthetic process (GO:0009145)3.13804765
62inner mitochondrial membrane organization (GO:0007007)3.13098172
63purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.12726268
64cellular ketone body metabolic process (GO:0046950)3.11202224
65protein targeting to membrane (GO:0006612)3.08098085
66rRNA metabolic process (GO:0016072)3.07523631
67hydrogen transport (GO:0006818)3.06731664
68histone exchange (GO:0043486)3.06265087
69sequestering of actin monomers (GO:0042989)3.05871657
70organelle disassembly (GO:1903008)3.04879871
71resolution of meiotic recombination intermediates (GO:0000712)3.04476904
72mRNA catabolic process (GO:0006402)2.99063153
73spliceosomal snRNP assembly (GO:0000387)2.97292233
74oxidative phosphorylation (GO:0006119)2.96736166
75pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.96084352
76intracellular protein transmembrane import (GO:0044743)2.94446830
77regulation of cellular amino acid metabolic process (GO:0006521)2.91452414
78positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.89286946
79regulation of DNA endoreduplication (GO:0032875)2.88091199
80negative regulation of ligase activity (GO:0051352)2.86428050
81negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.86428050
82establishment of protein localization to mitochondrion (GO:0072655)2.85635280
83regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.84471622
84protein localization to mitochondrion (GO:0070585)2.82499742
85RNA catabolic process (GO:0006401)2.82402052
86protein targeting to mitochondrion (GO:0006626)2.82211315
87ribonucleoside triphosphate biosynthetic process (GO:0009201)2.81199455
88DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.75892650
89DNA replication-independent nucleosome organization (GO:0034724)2.75465051
90DNA replication-independent nucleosome assembly (GO:0006336)2.75465051
91ketone body metabolic process (GO:1902224)2.73674859
92spliceosomal complex assembly (GO:0000245)2.71333435
93positive regulation of protein homodimerization activity (GO:0090073)2.70709170
94signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.68302639
95signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.68302639
96signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.68302639
97ubiquinone biosynthetic process (GO:0006744)2.66862397
98signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.66698857
99intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.66698857
100cytidine catabolic process (GO:0006216)2.66046429

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.86472439
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.56992270
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.42837680
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.06612754
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.46450421
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.33034689
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.16213989
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.06649246
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.99942829
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.82338687
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.68623565
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.56747148
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.54579535
14VDR_23849224_ChIP-Seq_CD4+_Human2.50201556
15VDR_22108803_ChIP-Seq_LS180_Human2.49566868
16EZH2_22144423_ChIP-Seq_EOC_Human2.46394347
17ELK1_19687146_ChIP-ChIP_HELA_Human2.43236927
18ZNF274_21170338_ChIP-Seq_K562_Hela2.28447898
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.27747902
20MYC_18940864_ChIP-ChIP_HL60_Human2.23183535
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.04993579
22MYC_18358816_ChIP-ChIP_MESCs_Mouse1.98139966
23FOXP3_21729870_ChIP-Seq_TREG_Human1.97078101
24E2F7_22180533_ChIP-Seq_HELA_Human1.91586817
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.89622527
26TTF2_22483619_ChIP-Seq_HELA_Human1.86165305
27EWS_26573619_Chip-Seq_HEK293_Human1.84199685
28MYC_19030024_ChIP-ChIP_MESCs_Mouse1.82807502
29PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.79361896
30IGF1R_20145208_ChIP-Seq_DFB_Human1.78472539
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.78333514
32POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.75185148
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.75046471
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.68147089
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.66557062
36XRN2_22483619_ChIP-Seq_HELA_Human1.65731029
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.59565394
38TP63_19390658_ChIP-ChIP_HaCaT_Human1.57128642
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.53458387
40FUS_26573619_Chip-Seq_HEK293_Human1.48851369
41E2F1_18555785_ChIP-Seq_MESCs_Mouse1.42137029
42POU5F1_16153702_ChIP-ChIP_HESCs_Human1.41874825
43GABP_19822575_ChIP-Seq_HepG2_Human1.35563047
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.34757305
45IRF1_19129219_ChIP-ChIP_H3396_Human1.33634001
46PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31875612
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.31238180
48TP53_22573176_ChIP-Seq_HFKS_Human1.30325112
49HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.30117640
50FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.25927263
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.25317436
52MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.24756043
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.24345952
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22898428
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.21676712
56GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19270922
57CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.19244960
58BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16396851
59EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.16280566
60FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.15542759
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.15300232
62SOX2_16153702_ChIP-ChIP_HESCs_Human1.15025361
63ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14343720
64ELK1_22589737_ChIP-Seq_MCF10A_Human1.12212964
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.10364482
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.09835439
67DCP1A_22483619_ChIP-Seq_HELA_Human1.09157414
68POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.06687506
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03386369
70PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03300021
71P300_19829295_ChIP-Seq_ESCs_Human1.02626402
72NANOG_16153702_ChIP-ChIP_HESCs_Human1.02512059
73CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01496559
74GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00967823
75SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00268722
76NCOR_22424771_ChIP-Seq_293T_Human0.99207355
77PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99031162
78CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.98208515
79AUTS2_25519132_ChIP-Seq_293T-REX_Human0.96467293
80RNF2_27304074_Chip-Seq_NSC_Mouse0.96367868
81GATA3_21878914_ChIP-Seq_MCF-7_Human0.95785546
82PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94654067
83HOXB4_20404135_ChIP-ChIP_EML_Mouse0.94634441
84FOXA1_27270436_Chip-Seq_PROSTATE_Human0.93640612
85FOXA1_25329375_ChIP-Seq_VCAP_Human0.93640612
86E2F1_21310950_ChIP-Seq_MCF-7_Human0.93501886
87ETV2_25802403_ChIP-Seq_MESCs_Mouse0.91151425
88ERG_20517297_ChIP-Seq_VCAP_Human0.89249721
89NANOG_19829295_ChIP-Seq_ESCs_Human0.87712006
90SOX2_19829295_ChIP-Seq_ESCs_Human0.87712006
91HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.86440063
92TAF15_26573619_Chip-Seq_HEK293_Human0.84892068
93KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84085989
94KAP1_22055183_ChIP-Seq_ESCs_Mouse0.82268591
95AR_20517297_ChIP-Seq_VCAP_Human0.81837726
96CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.79915431
97LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.79421676
98SOX2_18555785_ChIP-Seq_MESCs_Mouse0.78606314
99CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.78594758
100NELFA_20434984_ChIP-Seq_ESCs_Mouse0.77781742

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.40286901
2MP0006292_abnormal_olfactory_placode5.09905280
3MP0003136_yellow_coat_color3.76668234
4MP0001188_hyperpigmentation2.55072187
5MP0006072_abnormal_retinal_apoptosis2.09891770
6MP0008877_abnormal_DNA_methylation2.06585967
7MP0001293_anophthalmia2.03567751
8MP0002938_white_spotting2.03534429
9MP0004885_abnormal_endolymph1.90609292
10MP0005084_abnormal_gallbladder_morpholo1.89491422
11MP0008875_abnormal_xenobiotic_pharmacok1.85461397
12MP0003315_abnormal_perineum_morphology1.84549546
13MP0008058_abnormal_DNA_repair1.84239842
14MP0002736_abnormal_nociception_after1.74183040
15MP0001485_abnormal_pinna_reflex1.74112189
16MP0003880_abnormal_central_pattern1.64823062
17MP0003122_maternal_imprinting1.61375765
18MP0001919_abnormal_reproductive_system1.55852826
19MP0002277_abnormal_respiratory_mucosa1.54045662
20MP0002160_abnormal_reproductive_system1.51564962
21MP0006276_abnormal_autonomic_nervous1.51482192
22MP0005389_reproductive_system_phenotype1.49576190
23MP0004957_abnormal_blastocyst_morpholog1.49006877
24MP0002163_abnormal_gland_morphology1.46911979
25MP0002095_abnormal_skin_pigmentation1.45286377
26MP0004142_abnormal_muscle_tone1.44438956
27MP0003718_maternal_effect1.43403308
28MP0004133_heterotaxia1.42490750
29MP0010094_abnormal_chromosome_stability1.38955568
30MP0000778_abnormal_nervous_system1.38313526
31MP0002102_abnormal_ear_morphology1.37394097
32MP0008872_abnormal_physiological_respon1.35317870
33MP0002837_dystrophic_cardiac_calcinosis1.34297570
34MP0001968_abnormal_touch/_nociception1.34067485
35MP0008789_abnormal_olfactory_epithelium1.33722214
36MP0001529_abnormal_vocalization1.33144426
37MP0000631_abnormal_neuroendocrine_gland1.32464145
38MP0001286_abnormal_eye_development1.32348833
39MP0006036_abnormal_mitochondrial_physio1.30402631
40MP0000049_abnormal_middle_ear1.29554438
41MP0005187_abnormal_penis_morphology1.25923184
42MP0002928_abnormal_bile_duct1.24099957
43MP0001905_abnormal_dopamine_level1.23824711
44MP0003567_abnormal_fetal_cardiomyocyte1.23200800
45MP0003121_genomic_imprinting1.21962611
46MP0004145_abnormal_muscle_electrophysio1.21842208
47MP0005645_abnormal_hypothalamus_physiol1.20774442
48MP0003011_delayed_dark_adaptation1.20768497
49MP0000372_irregular_coat_pigmentation1.20670348
50MP0009745_abnormal_behavioral_response1.20226115
51MP0003938_abnormal_ear_development1.19260754
52MP0005646_abnormal_pituitary_gland1.15451611
53MP0005551_abnormal_eye_electrophysiolog1.11971533
54MP0003937_abnormal_limbs/digits/tail_de1.11779234
55MP0009697_abnormal_copulation1.09765389
56MP0003693_abnormal_embryo_hatching1.07209034
57MP0005377_hearing/vestibular/ear_phenot1.06944358
58MP0003878_abnormal_ear_physiology1.06944358
59MP0000026_abnormal_inner_ear1.05932436
60MP0003186_abnormal_redox_activity1.02360560
61MP0002272_abnormal_nervous_system1.00910338
62MP0002210_abnormal_sex_determination1.00280339
63MP0005671_abnormal_response_to0.99021957
64MP0005195_abnormal_posterior_eye0.98913240
65MP0002138_abnormal_hepatobiliary_system0.98577375
66MP0002876_abnormal_thyroid_physiology0.98314275
67MP0005075_abnormal_melanosome_morpholog0.98296695
68MP0003890_abnormal_embryonic-extraembry0.97734284
69MP0003787_abnormal_imprinting0.97091385
70MP0005253_abnormal_eye_physiology0.94825476
71MP0002752_abnormal_somatic_nervous0.93368719
72MP0008932_abnormal_embryonic_tissue0.90034736
73MP0004742_abnormal_vestibular_system0.88423499
74MP0001764_abnormal_homeostasis0.87248646
75MP0002282_abnormal_trachea_morphology0.84877647
76MP0008995_early_reproductive_senescence0.84376554
77MP0001440_abnormal_grooming_behavior0.84263342
78MP0003786_premature_aging0.84093272
79MP0005499_abnormal_olfactory_system0.84052349
80MP0005394_taste/olfaction_phenotype0.84052349
81MP0001486_abnormal_startle_reflex0.83695668
82MP0002234_abnormal_pharynx_morphology0.80346233
83MP0004147_increased_porphyrin_level0.76770769
84MP0005174_abnormal_tail_pigmentation0.74564533
85MP0001970_abnormal_pain_threshold0.74038645
86MP0000653_abnormal_sex_gland0.72671794
87MP0005379_endocrine/exocrine_gland_phen0.72174698
88MP0000647_abnormal_sebaceous_gland0.72026146
89MP0001963_abnormal_hearing_physiology0.71749543
90MP0001145_abnormal_male_reproductive0.69227812
91MP0002697_abnormal_eye_size0.69022971
92MP0002557_abnormal_social/conspecific_i0.68271161
93MP0002638_abnormal_pupillary_reflex0.67775998
94MP0002733_abnormal_thermal_nociception0.67751461
95MP0003936_abnormal_reproductive_system0.66407909
96MP0002653_abnormal_ependyma_morphology0.66193429
97MP0002006_tumorigenesis0.65839604
98MP0001929_abnormal_gametogenesis0.63900745
99MP0003861_abnormal_nervous_system0.63180482
100MP0002184_abnormal_innervation0.62176678

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.16759742
2Mitochondrial inheritance (HP:0001427)4.62997909
3Abnormal mitochondria in muscle tissue (HP:0008316)4.46222833
4Acute encephalopathy (HP:0006846)4.40810040
5Progressive macrocephaly (HP:0004481)4.23002154
6Increased hepatocellular lipid droplets (HP:0006565)4.20667353
7Increased CSF lactate (HP:0002490)4.17897103
8Hepatocellular necrosis (HP:0001404)4.01984092
9Lipid accumulation in hepatocytes (HP:0006561)3.84538318
10Macrocytic anemia (HP:0001972)3.82687188
11Abnormality of cells of the erythroid lineage (HP:0012130)3.75321955
12Abnormal number of erythroid precursors (HP:0012131)3.67485735
13Hepatic necrosis (HP:0002605)3.57964370
14Reticulocytopenia (HP:0001896)3.50236685
15Cerebral edema (HP:0002181)3.38368570
16Septo-optic dysplasia (HP:0100842)3.32768121
17Renal Fanconi syndrome (HP:0001994)3.15473264
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.13419176
19True hermaphroditism (HP:0010459)3.11371758
20Abnormality of the labia minora (HP:0012880)3.04788637
21Optic disc pallor (HP:0000543)2.96031051
22Pancreatic fibrosis (HP:0100732)2.83036134
23Pancreatic cysts (HP:0001737)2.76999434
24Type II lissencephaly (HP:0007260)2.75308509
25Increased serum lactate (HP:0002151)2.70122145
26Aplastic anemia (HP:0001915)2.69851716
27Hyperglycinemia (HP:0002154)2.64371872
28Severe combined immunodeficiency (HP:0004430)2.63729240
29Colon cancer (HP:0003003)2.61364855
30Leukodystrophy (HP:0002415)2.58515602
31Pallor (HP:0000980)2.52633855
32B lymphocytopenia (HP:0010976)2.49748362
33Increased intramyocellular lipid droplets (HP:0012240)2.48865204
343-Methylglutaconic aciduria (HP:0003535)2.48018344
35Abnormality of midbrain morphology (HP:0002418)2.46848942
36Molar tooth sign on MRI (HP:0002419)2.46848942
37Congenital, generalized hypertrichosis (HP:0004540)2.43732677
38Pendular nystagmus (HP:0012043)2.41927702
39Methylmalonic acidemia (HP:0002912)2.41888059
40Exertional dyspnea (HP:0002875)2.41775520
41Abnormality of B cell number (HP:0010975)2.38894296
42Respiratory failure (HP:0002878)2.34373830
43Supernumerary spleens (HP:0009799)2.33505276
44Rib fusion (HP:0000902)2.33153831
45Decreased central vision (HP:0007663)2.33130191
46Lactic acidosis (HP:0003128)2.24695384
47Nephronophthisis (HP:0000090)2.23634835
48Megaloblastic anemia (HP:0001889)2.20975901
49Cerebellar dysplasia (HP:0007033)2.18333627
50Absent septum pellucidum (HP:0001331)2.17381352
51Myokymia (HP:0002411)2.15237636
52Abnormal number of incisors (HP:0011064)2.13965940
53Abnormality of renal resorption (HP:0011038)2.13397641
54Lethargy (HP:0001254)2.12149008
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.10786544
56Maternal diabetes (HP:0009800)2.09538050
57Exercise intolerance (HP:0003546)2.07679069
58Combined immunodeficiency (HP:0005387)2.05102955
59Absent rod-and cone-mediated responses on ERG (HP:0007688)2.04368930
60Increased muscle lipid content (HP:0009058)2.03549050
61Hypoplasia of the pons (HP:0012110)2.03382863
62Thyroiditis (HP:0100646)2.02159603
63Panhypogammaglobulinemia (HP:0003139)2.01582912
64Respiratory difficulties (HP:0002880)2.01468082
65Chronic sinusitis (HP:0011109)2.01142236
66Methylmalonic aciduria (HP:0012120)1.99728343
67Oral leukoplakia (HP:0002745)1.99474167
68Congenital stationary night blindness (HP:0007642)1.97632686
69Sclerocornea (HP:0000647)1.96743134
70Absent thumb (HP:0009777)1.93311892
71Abnormality of the pons (HP:0007361)1.90730015
72Optic nerve hypoplasia (HP:0000609)1.90272321
73Abnormal rod and cone electroretinograms (HP:0008323)1.86826685
74Microvesicular hepatic steatosis (HP:0001414)1.86479291
75Decreased activity of mitochondrial respiratory chain (HP:0008972)1.86411152
76Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.86411152
77Chronic hepatic failure (HP:0100626)1.85971744
78Glycosuria (HP:0003076)1.84879263
79Abnormality of urine glucose concentration (HP:0011016)1.84879263
80Aplasia/hypoplasia of the uterus (HP:0008684)1.84855684
81Male pseudohermaphroditism (HP:0000037)1.83681567
82Medial flaring of the eyebrow (HP:0010747)1.81928191
83Pancytopenia (HP:0001876)1.80854574
84Constricted visual fields (HP:0001133)1.80852692
85Hyperglycinuria (HP:0003108)1.79914918
86Attenuation of retinal blood vessels (HP:0007843)1.74801450
87Anencephaly (HP:0002323)1.73466234
88Bony spicule pigmentary retinopathy (HP:0007737)1.70885990
89X-linked dominant inheritance (HP:0001423)1.70321421
90Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.70308166
91Hyperphosphaturia (HP:0003109)1.70027434
92Sensory axonal neuropathy (HP:0003390)1.69942758
93Cleft eyelid (HP:0000625)1.68607549
94Abnormality of serine family amino acid metabolism (HP:0010894)1.68513357
95Abnormality of glycine metabolism (HP:0010895)1.68513357
96Abnormality of serum amino acid levels (HP:0003112)1.67699226
97Abnormality of the ileum (HP:0001549)1.65762891
98Bile duct proliferation (HP:0001408)1.65248778
99Abnormal biliary tract physiology (HP:0012439)1.65248778
100Abnormality of aspartate family amino acid metabolism (HP:0010899)1.65037179

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.69658542
2MAP3K123.74105837
3VRK13.30194052
4STK162.91236218
5ZAK2.79990722
6TAF12.73194738
7WNK42.51423442
8WNK32.38344124
9TLK12.34409117
10TNIK2.18105582
11SRPK12.08636660
12NUAK12.05543276
13CDC72.03420318
14DYRK22.02798467
15STK391.86050747
16PASK1.79233026
17MAPK151.77028444
18ADRBK21.75960051
19EIF2AK31.75158909
20NME11.75016992
21MKNK21.69227023
22PLK31.62262562
23PNCK1.56175234
24MST41.55256211
25BUB11.47793089
26MAP3K111.41872200
27DYRK31.41745678
28PLK41.40315784
29KDR1.37547794
30BMPR1B1.35066451
31PLK21.32004526
32GRK11.29258117
33CDK191.28732290
34TSSK61.28559349
35BCKDK1.22808581
36OXSR11.17243657
37MKNK11.09683553
38WEE11.03340674
39TESK21.02083839
40PRKCG1.01717767
41EPHB20.96692471
42NEK10.94637888
43MAPKAPK50.86712840
44MAP2K40.85187280
45CSNK2A20.85089241
46PLK10.84296647
47AURKB0.81968818
48RPS6KA40.79861481
49EIF2AK10.79674996
50PBK0.79324804
51RPS6KA50.78901826
52MAP4K20.73770811
53TXK0.69636345
54CSNK2A10.67896727
55TGFBR10.65954695
56MAP2K70.65125120
57TRIM280.63833107
58PRKCI0.62772799
59AURKA0.62207401
60SIK20.61643698
61MAP3K40.60621969
62CDK80.58875060
63MARK10.58496194
64INSRR0.57946836
65MAPK130.57560485
66NEK20.57530596
67CASK0.56124152
68EIF2AK20.55892461
69PINK10.55796174
70PHKG20.55004346
71PHKG10.55004346
72MINK10.53127545
73CSNK1E0.52680004
74TAOK30.50556447
75DYRK1A0.50030772
76FRK0.49875733
77WNK10.49629572
78ATR0.49223137
79ACVR1B0.41652159
80CHEK20.40448520
81PRKCE0.40240024
82TIE10.39547198
83DAPK30.38824697
84STK240.37456406
85CSNK1A10.36538635
86PRKACA0.36475686
87PRKG10.36462307
88LRRK20.36414049
89PIM10.34908030
90CDK90.34298802
91SGK10.33156163
92STK38L0.33009822
93CDK30.31947120
94STK110.31179406
95PRKCQ0.30841021
96CDK70.30705546
97ADRBK10.30090635
98ALK0.30011859
99ABL20.28171702
100ATM0.26995658

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.02614301
2Oxidative phosphorylation_Homo sapiens_hsa001904.69051207
3Parkinsons disease_Homo sapiens_hsa050124.02947336
4Proteasome_Homo sapiens_hsa030503.88673921
5Huntingtons disease_Homo sapiens_hsa050162.81560142
6RNA polymerase_Homo sapiens_hsa030202.79520225
7Alzheimers disease_Homo sapiens_hsa050102.72968586
8Protein export_Homo sapiens_hsa030602.62584932
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.47515176
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.46457982
11Cardiac muscle contraction_Homo sapiens_hsa042602.24028555
12DNA replication_Homo sapiens_hsa030302.20992118
13Caffeine metabolism_Homo sapiens_hsa002322.15927099
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.12579690
15Mismatch repair_Homo sapiens_hsa034302.03131682
16Spliceosome_Homo sapiens_hsa030401.98663553
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.89999182
18RNA degradation_Homo sapiens_hsa030181.87572251
19Non-homologous end-joining_Homo sapiens_hsa034501.79872032
20Homologous recombination_Homo sapiens_hsa034401.69511301
21Nucleotide excision repair_Homo sapiens_hsa034201.48864452
22One carbon pool by folate_Homo sapiens_hsa006701.42215923
23Basal transcription factors_Homo sapiens_hsa030221.37888229
24Butanoate metabolism_Homo sapiens_hsa006501.35686435
25Primary immunodeficiency_Homo sapiens_hsa053401.35575236
26RNA transport_Homo sapiens_hsa030131.34332804
27Base excision repair_Homo sapiens_hsa034101.33531654
28Pyrimidine metabolism_Homo sapiens_hsa002401.30704347
29Fanconi anemia pathway_Homo sapiens_hsa034601.26910399
30Asthma_Homo sapiens_hsa053101.23757836
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.14966405
32Linoleic acid metabolism_Homo sapiens_hsa005911.11729846
33Propanoate metabolism_Homo sapiens_hsa006401.10511095
34Maturity onset diabetes of the young_Homo sapiens_hsa049501.09790363
35Purine metabolism_Homo sapiens_hsa002300.96363005
36Selenocompound metabolism_Homo sapiens_hsa004500.95378485
37Intestinal immune network for IgA production_Homo sapiens_hsa046720.95031752
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.92097666
39alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91355523
40Phototransduction_Homo sapiens_hsa047440.86320276
41Allograft rejection_Homo sapiens_hsa053300.76354315
42Cysteine and methionine metabolism_Homo sapiens_hsa002700.74560667
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73360636
44Tryptophan metabolism_Homo sapiens_hsa003800.72872537
45Autoimmune thyroid disease_Homo sapiens_hsa053200.72677332
46Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72188485
47Nicotine addiction_Homo sapiens_hsa050330.71865363
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70179124
49Metabolic pathways_Homo sapiens_hsa011000.69767996
50Folate biosynthesis_Homo sapiens_hsa007900.69587682
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68420886
52Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.68299218
53Glutathione metabolism_Homo sapiens_hsa004800.68208948
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.67827900
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.66742062
56Olfactory transduction_Homo sapiens_hsa047400.65861291
57Vitamin digestion and absorption_Homo sapiens_hsa049770.63591730
58Pyruvate metabolism_Homo sapiens_hsa006200.63076689
59Peroxisome_Homo sapiens_hsa041460.59900248
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.58612052
61Type I diabetes mellitus_Homo sapiens_hsa049400.56199390
62Nitrogen metabolism_Homo sapiens_hsa009100.54109718
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52661555
64Sulfur relay system_Homo sapiens_hsa041220.51229422
65Hematopoietic cell lineage_Homo sapiens_hsa046400.49575098
66Hedgehog signaling pathway_Homo sapiens_hsa043400.49197308
67Antigen processing and presentation_Homo sapiens_hsa046120.49000557
68mRNA surveillance pathway_Homo sapiens_hsa030150.48702905
69Chemical carcinogenesis_Homo sapiens_hsa052040.48429463
70Systemic lupus erythematosus_Homo sapiens_hsa053220.48206679
71Graft-versus-host disease_Homo sapiens_hsa053320.46568639
72Collecting duct acid secretion_Homo sapiens_hsa049660.45272179
73Ether lipid metabolism_Homo sapiens_hsa005650.44611542
74Arachidonic acid metabolism_Homo sapiens_hsa005900.44576299
75Sulfur metabolism_Homo sapiens_hsa009200.42100036
76Basal cell carcinoma_Homo sapiens_hsa052170.41087666
77Fat digestion and absorption_Homo sapiens_hsa049750.37591347
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.35838930
79Retinol metabolism_Homo sapiens_hsa008300.33306944
80Cell cycle_Homo sapiens_hsa041100.32940032
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.32033424
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30442819
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.30072745
84Morphine addiction_Homo sapiens_hsa050320.29419581
85Taste transduction_Homo sapiens_hsa047420.25751916
86Drug metabolism - other enzymes_Homo sapiens_hsa009830.24221970
87Serotonergic synapse_Homo sapiens_hsa047260.23430550
88Epstein-Barr virus infection_Homo sapiens_hsa051690.22578865
89Fatty acid metabolism_Homo sapiens_hsa012120.20900699
90beta-Alanine metabolism_Homo sapiens_hsa004100.19336140
91Fatty acid elongation_Homo sapiens_hsa000620.17879695
92Starch and sucrose metabolism_Homo sapiens_hsa005000.17531381
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.17393484
94Rheumatoid arthritis_Homo sapiens_hsa053230.16417684
95Mineral absorption_Homo sapiens_hsa049780.14638732
96Vitamin B6 metabolism_Homo sapiens_hsa007500.13735057
97Carbon metabolism_Homo sapiens_hsa012000.12575684
98Alcoholism_Homo sapiens_hsa050340.12364703
99Steroid biosynthesis_Homo sapiens_hsa001000.11843772
100Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.11804434

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