

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.74288157 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.66191099 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 6.25646871 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.25646871 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 5.96952955 |
| 6 | viral transcription (GO:0019083) | 5.53850861 |
| 7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.49785176 |
| 8 | translational termination (GO:0006415) | 5.43295983 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 5.42587825 |
| 10 | respiratory electron transport chain (GO:0022904) | 5.22130123 |
| 11 | electron transport chain (GO:0022900) | 5.12558459 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 5.05793568 |
| 13 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.79230209 |
| 14 | cotranslational protein targeting to membrane (GO:0006613) | 4.76217704 |
| 15 | protein targeting to ER (GO:0045047) | 4.73844093 |
| 16 | translational elongation (GO:0006414) | 4.73460018 |
| 17 | protein neddylation (GO:0045116) | 4.61357598 |
| 18 | proteasome assembly (GO:0043248) | 4.56857730 |
| 19 | DNA deamination (GO:0045006) | 4.55905372 |
| 20 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.54492580 |
| 21 | protein localization to endoplasmic reticulum (GO:0070972) | 4.41016174 |
| 22 | ribosomal small subunit biogenesis (GO:0042274) | 4.40476131 |
| 23 | protein complex biogenesis (GO:0070271) | 4.30454754 |
| 24 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.19541787 |
| 25 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.19541787 |
| 26 | NADH dehydrogenase complex assembly (GO:0010257) | 4.19541787 |
| 27 | viral life cycle (GO:0019058) | 4.16111395 |
| 28 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.14177789 |
| 29 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.12414492 |
| 30 | cellular protein complex disassembly (GO:0043624) | 4.11603586 |
| 31 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.08953113 |
| 32 | behavioral response to nicotine (GO:0035095) | 4.08557581 |
| 33 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.05418283 |
| 34 | translational initiation (GO:0006413) | 3.97478726 |
| 35 | translation (GO:0006412) | 3.95886336 |
| 36 | chromatin remodeling at centromere (GO:0031055) | 3.77678993 |
| 37 | ribosomal large subunit biogenesis (GO:0042273) | 3.73053610 |
| 38 | protein-cofactor linkage (GO:0018065) | 3.70636514 |
| 39 | CENP-A containing nucleosome assembly (GO:0034080) | 3.65194801 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.63220755 |
| 41 | DNA damage response, detection of DNA damage (GO:0042769) | 3.55109783 |
| 42 | protein complex disassembly (GO:0043241) | 3.50785800 |
| 43 | hydrogen ion transmembrane transport (GO:1902600) | 3.47847804 |
| 44 | macromolecular complex disassembly (GO:0032984) | 3.42425754 |
| 45 | ATP biosynthetic process (GO:0006754) | 3.41065980 |
| 46 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.38852546 |
| 47 | termination of RNA polymerase III transcription (GO:0006386) | 3.38852546 |
| 48 | pseudouridine synthesis (GO:0001522) | 3.36147814 |
| 49 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.32590284 |
| 50 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.30019179 |
| 51 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.30019179 |
| 52 | cytochrome complex assembly (GO:0017004) | 3.28213622 |
| 53 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.20373728 |
| 54 | rRNA modification (GO:0000154) | 3.20359570 |
| 55 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.18625985 |
| 56 | rRNA processing (GO:0006364) | 3.16885906 |
| 57 | cellular component biogenesis (GO:0044085) | 3.16240307 |
| 58 | proton transport (GO:0015992) | 3.16080122 |
| 59 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.14203558 |
| 60 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.13850574 |
| 61 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.13804765 |
| 62 | inner mitochondrial membrane organization (GO:0007007) | 3.13098172 |
| 63 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.12726268 |
| 64 | cellular ketone body metabolic process (GO:0046950) | 3.11202224 |
| 65 | protein targeting to membrane (GO:0006612) | 3.08098085 |
| 66 | rRNA metabolic process (GO:0016072) | 3.07523631 |
| 67 | hydrogen transport (GO:0006818) | 3.06731664 |
| 68 | histone exchange (GO:0043486) | 3.06265087 |
| 69 | sequestering of actin monomers (GO:0042989) | 3.05871657 |
| 70 | organelle disassembly (GO:1903008) | 3.04879871 |
| 71 | resolution of meiotic recombination intermediates (GO:0000712) | 3.04476904 |
| 72 | mRNA catabolic process (GO:0006402) | 2.99063153 |
| 73 | spliceosomal snRNP assembly (GO:0000387) | 2.97292233 |
| 74 | oxidative phosphorylation (GO:0006119) | 2.96736166 |
| 75 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.96084352 |
| 76 | intracellular protein transmembrane import (GO:0044743) | 2.94446830 |
| 77 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.91452414 |
| 78 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.89286946 |
| 79 | regulation of DNA endoreduplication (GO:0032875) | 2.88091199 |
| 80 | negative regulation of ligase activity (GO:0051352) | 2.86428050 |
| 81 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.86428050 |
| 82 | establishment of protein localization to mitochondrion (GO:0072655) | 2.85635280 |
| 83 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.84471622 |
| 84 | protein localization to mitochondrion (GO:0070585) | 2.82499742 |
| 85 | RNA catabolic process (GO:0006401) | 2.82402052 |
| 86 | protein targeting to mitochondrion (GO:0006626) | 2.82211315 |
| 87 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.81199455 |
| 88 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.75892650 |
| 89 | DNA replication-independent nucleosome organization (GO:0034724) | 2.75465051 |
| 90 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.75465051 |
| 91 | ketone body metabolic process (GO:1902224) | 2.73674859 |
| 92 | spliceosomal complex assembly (GO:0000245) | 2.71333435 |
| 93 | positive regulation of protein homodimerization activity (GO:0090073) | 2.70709170 |
| 94 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.68302639 |
| 95 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.68302639 |
| 96 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.68302639 |
| 97 | ubiquinone biosynthetic process (GO:0006744) | 2.66862397 |
| 98 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.66698857 |
| 99 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.66698857 |
| 100 | cytidine catabolic process (GO:0006216) | 2.66046429 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.86472439 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.56992270 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.42837680 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.06612754 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.46450421 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.33034689 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.16213989 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.06649246 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.99942829 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.82338687 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.68623565 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.56747148 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.54579535 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.50201556 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.49566868 |
| 16 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.46394347 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.43236927 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.28447898 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.27747902 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.23183535 |
| 21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.04993579 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.98139966 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97078101 |
| 24 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.91586817 |
| 25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.89622527 |
| 26 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.86165305 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84199685 |
| 28 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.82807502 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.79361896 |
| 30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.78472539 |
| 31 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.78333514 |
| 32 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.75185148 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75046471 |
| 34 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.68147089 |
| 35 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66557062 |
| 36 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.65731029 |
| 37 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.59565394 |
| 38 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.57128642 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.53458387 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.48851369 |
| 41 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.42137029 |
| 42 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.41874825 |
| 43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.35563047 |
| 44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.34757305 |
| 45 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.33634001 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.31875612 |
| 47 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31238180 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30325112 |
| 49 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.30117640 |
| 50 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.25927263 |
| 51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.25317436 |
| 52 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24756043 |
| 53 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.24345952 |
| 54 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.22898428 |
| 55 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21676712 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19270922 |
| 57 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.19244960 |
| 58 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.16396851 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.16280566 |
| 60 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.15542759 |
| 61 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.15300232 |
| 62 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.15025361 |
| 63 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.14343720 |
| 64 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.12212964 |
| 65 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.10364482 |
| 66 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.09835439 |
| 67 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.09157414 |
| 68 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.06687506 |
| 69 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03386369 |
| 70 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.03300021 |
| 71 | P300_19829295_ChIP-Seq_ESCs_Human | 1.02626402 |
| 72 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.02512059 |
| 73 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.01496559 |
| 74 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00967823 |
| 75 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.00268722 |
| 76 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99207355 |
| 77 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.99031162 |
| 78 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.98208515 |
| 79 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96467293 |
| 80 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96367868 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.95785546 |
| 82 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.94654067 |
| 83 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.94634441 |
| 84 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93640612 |
| 85 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93640612 |
| 86 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.93501886 |
| 87 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.91151425 |
| 88 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.89249721 |
| 89 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.87712006 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.87712006 |
| 91 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.86440063 |
| 92 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.84892068 |
| 93 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.84085989 |
| 94 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.82268591 |
| 95 | AR_20517297_ChIP-Seq_VCAP_Human | 0.81837726 |
| 96 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.79915431 |
| 97 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.79421676 |
| 98 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.78606314 |
| 99 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.78594758 |
| 100 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.77781742 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.40286901 |
| 2 | MP0006292_abnormal_olfactory_placode | 5.09905280 |
| 3 | MP0003136_yellow_coat_color | 3.76668234 |
| 4 | MP0001188_hyperpigmentation | 2.55072187 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.09891770 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.06585967 |
| 7 | MP0001293_anophthalmia | 2.03567751 |
| 8 | MP0002938_white_spotting | 2.03534429 |
| 9 | MP0004885_abnormal_endolymph | 1.90609292 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 1.89491422 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 1.85461397 |
| 12 | MP0003315_abnormal_perineum_morphology | 1.84549546 |
| 13 | MP0008058_abnormal_DNA_repair | 1.84239842 |
| 14 | MP0002736_abnormal_nociception_after | 1.74183040 |
| 15 | MP0001485_abnormal_pinna_reflex | 1.74112189 |
| 16 | MP0003880_abnormal_central_pattern | 1.64823062 |
| 17 | MP0003122_maternal_imprinting | 1.61375765 |
| 18 | MP0001919_abnormal_reproductive_system | 1.55852826 |
| 19 | MP0002277_abnormal_respiratory_mucosa | 1.54045662 |
| 20 | MP0002160_abnormal_reproductive_system | 1.51564962 |
| 21 | MP0006276_abnormal_autonomic_nervous | 1.51482192 |
| 22 | MP0005389_reproductive_system_phenotype | 1.49576190 |
| 23 | MP0004957_abnormal_blastocyst_morpholog | 1.49006877 |
| 24 | MP0002163_abnormal_gland_morphology | 1.46911979 |
| 25 | MP0002095_abnormal_skin_pigmentation | 1.45286377 |
| 26 | MP0004142_abnormal_muscle_tone | 1.44438956 |
| 27 | MP0003718_maternal_effect | 1.43403308 |
| 28 | MP0004133_heterotaxia | 1.42490750 |
| 29 | MP0010094_abnormal_chromosome_stability | 1.38955568 |
| 30 | MP0000778_abnormal_nervous_system | 1.38313526 |
| 31 | MP0002102_abnormal_ear_morphology | 1.37394097 |
| 32 | MP0008872_abnormal_physiological_respon | 1.35317870 |
| 33 | MP0002837_dystrophic_cardiac_calcinosis | 1.34297570 |
| 34 | MP0001968_abnormal_touch/_nociception | 1.34067485 |
| 35 | MP0008789_abnormal_olfactory_epithelium | 1.33722214 |
| 36 | MP0001529_abnormal_vocalization | 1.33144426 |
| 37 | MP0000631_abnormal_neuroendocrine_gland | 1.32464145 |
| 38 | MP0001286_abnormal_eye_development | 1.32348833 |
| 39 | MP0006036_abnormal_mitochondrial_physio | 1.30402631 |
| 40 | MP0000049_abnormal_middle_ear | 1.29554438 |
| 41 | MP0005187_abnormal_penis_morphology | 1.25923184 |
| 42 | MP0002928_abnormal_bile_duct | 1.24099957 |
| 43 | MP0001905_abnormal_dopamine_level | 1.23824711 |
| 44 | MP0003567_abnormal_fetal_cardiomyocyte | 1.23200800 |
| 45 | MP0003121_genomic_imprinting | 1.21962611 |
| 46 | MP0004145_abnormal_muscle_electrophysio | 1.21842208 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.20774442 |
| 48 | MP0003011_delayed_dark_adaptation | 1.20768497 |
| 49 | MP0000372_irregular_coat_pigmentation | 1.20670348 |
| 50 | MP0009745_abnormal_behavioral_response | 1.20226115 |
| 51 | MP0003938_abnormal_ear_development | 1.19260754 |
| 52 | MP0005646_abnormal_pituitary_gland | 1.15451611 |
| 53 | MP0005551_abnormal_eye_electrophysiolog | 1.11971533 |
| 54 | MP0003937_abnormal_limbs/digits/tail_de | 1.11779234 |
| 55 | MP0009697_abnormal_copulation | 1.09765389 |
| 56 | MP0003693_abnormal_embryo_hatching | 1.07209034 |
| 57 | MP0005377_hearing/vestibular/ear_phenot | 1.06944358 |
| 58 | MP0003878_abnormal_ear_physiology | 1.06944358 |
| 59 | MP0000026_abnormal_inner_ear | 1.05932436 |
| 60 | MP0003186_abnormal_redox_activity | 1.02360560 |
| 61 | MP0002272_abnormal_nervous_system | 1.00910338 |
| 62 | MP0002210_abnormal_sex_determination | 1.00280339 |
| 63 | MP0005671_abnormal_response_to | 0.99021957 |
| 64 | MP0005195_abnormal_posterior_eye | 0.98913240 |
| 65 | MP0002138_abnormal_hepatobiliary_system | 0.98577375 |
| 66 | MP0002876_abnormal_thyroid_physiology | 0.98314275 |
| 67 | MP0005075_abnormal_melanosome_morpholog | 0.98296695 |
| 68 | MP0003890_abnormal_embryonic-extraembry | 0.97734284 |
| 69 | MP0003787_abnormal_imprinting | 0.97091385 |
| 70 | MP0005253_abnormal_eye_physiology | 0.94825476 |
| 71 | MP0002752_abnormal_somatic_nervous | 0.93368719 |
| 72 | MP0008932_abnormal_embryonic_tissue | 0.90034736 |
| 73 | MP0004742_abnormal_vestibular_system | 0.88423499 |
| 74 | MP0001764_abnormal_homeostasis | 0.87248646 |
| 75 | MP0002282_abnormal_trachea_morphology | 0.84877647 |
| 76 | MP0008995_early_reproductive_senescence | 0.84376554 |
| 77 | MP0001440_abnormal_grooming_behavior | 0.84263342 |
| 78 | MP0003786_premature_aging | 0.84093272 |
| 79 | MP0005499_abnormal_olfactory_system | 0.84052349 |
| 80 | MP0005394_taste/olfaction_phenotype | 0.84052349 |
| 81 | MP0001486_abnormal_startle_reflex | 0.83695668 |
| 82 | MP0002234_abnormal_pharynx_morphology | 0.80346233 |
| 83 | MP0004147_increased_porphyrin_level | 0.76770769 |
| 84 | MP0005174_abnormal_tail_pigmentation | 0.74564533 |
| 85 | MP0001970_abnormal_pain_threshold | 0.74038645 |
| 86 | MP0000653_abnormal_sex_gland | 0.72671794 |
| 87 | MP0005379_endocrine/exocrine_gland_phen | 0.72174698 |
| 88 | MP0000647_abnormal_sebaceous_gland | 0.72026146 |
| 89 | MP0001963_abnormal_hearing_physiology | 0.71749543 |
| 90 | MP0001145_abnormal_male_reproductive | 0.69227812 |
| 91 | MP0002697_abnormal_eye_size | 0.69022971 |
| 92 | MP0002557_abnormal_social/conspecific_i | 0.68271161 |
| 93 | MP0002638_abnormal_pupillary_reflex | 0.67775998 |
| 94 | MP0002733_abnormal_thermal_nociception | 0.67751461 |
| 95 | MP0003936_abnormal_reproductive_system | 0.66407909 |
| 96 | MP0002653_abnormal_ependyma_morphology | 0.66193429 |
| 97 | MP0002006_tumorigenesis | 0.65839604 |
| 98 | MP0001929_abnormal_gametogenesis | 0.63900745 |
| 99 | MP0003861_abnormal_nervous_system | 0.63180482 |
| 100 | MP0002184_abnormal_innervation | 0.62176678 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.16759742 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.62997909 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.46222833 |
| 4 | Acute encephalopathy (HP:0006846) | 4.40810040 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.23002154 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.20667353 |
| 7 | Increased CSF lactate (HP:0002490) | 4.17897103 |
| 8 | Hepatocellular necrosis (HP:0001404) | 4.01984092 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.84538318 |
| 10 | Macrocytic anemia (HP:0001972) | 3.82687188 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.75321955 |
| 12 | Abnormal number of erythroid precursors (HP:0012131) | 3.67485735 |
| 13 | Hepatic necrosis (HP:0002605) | 3.57964370 |
| 14 | Reticulocytopenia (HP:0001896) | 3.50236685 |
| 15 | Cerebral edema (HP:0002181) | 3.38368570 |
| 16 | Septo-optic dysplasia (HP:0100842) | 3.32768121 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.15473264 |
| 18 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.13419176 |
| 19 | True hermaphroditism (HP:0010459) | 3.11371758 |
| 20 | Abnormality of the labia minora (HP:0012880) | 3.04788637 |
| 21 | Optic disc pallor (HP:0000543) | 2.96031051 |
| 22 | Pancreatic fibrosis (HP:0100732) | 2.83036134 |
| 23 | Pancreatic cysts (HP:0001737) | 2.76999434 |
| 24 | Type II lissencephaly (HP:0007260) | 2.75308509 |
| 25 | Increased serum lactate (HP:0002151) | 2.70122145 |
| 26 | Aplastic anemia (HP:0001915) | 2.69851716 |
| 27 | Hyperglycinemia (HP:0002154) | 2.64371872 |
| 28 | Severe combined immunodeficiency (HP:0004430) | 2.63729240 |
| 29 | Colon cancer (HP:0003003) | 2.61364855 |
| 30 | Leukodystrophy (HP:0002415) | 2.58515602 |
| 31 | Pallor (HP:0000980) | 2.52633855 |
| 32 | B lymphocytopenia (HP:0010976) | 2.49748362 |
| 33 | Increased intramyocellular lipid droplets (HP:0012240) | 2.48865204 |
| 34 | 3-Methylglutaconic aciduria (HP:0003535) | 2.48018344 |
| 35 | Abnormality of midbrain morphology (HP:0002418) | 2.46848942 |
| 36 | Molar tooth sign on MRI (HP:0002419) | 2.46848942 |
| 37 | Congenital, generalized hypertrichosis (HP:0004540) | 2.43732677 |
| 38 | Pendular nystagmus (HP:0012043) | 2.41927702 |
| 39 | Methylmalonic acidemia (HP:0002912) | 2.41888059 |
| 40 | Exertional dyspnea (HP:0002875) | 2.41775520 |
| 41 | Abnormality of B cell number (HP:0010975) | 2.38894296 |
| 42 | Respiratory failure (HP:0002878) | 2.34373830 |
| 43 | Supernumerary spleens (HP:0009799) | 2.33505276 |
| 44 | Rib fusion (HP:0000902) | 2.33153831 |
| 45 | Decreased central vision (HP:0007663) | 2.33130191 |
| 46 | Lactic acidosis (HP:0003128) | 2.24695384 |
| 47 | Nephronophthisis (HP:0000090) | 2.23634835 |
| 48 | Megaloblastic anemia (HP:0001889) | 2.20975901 |
| 49 | Cerebellar dysplasia (HP:0007033) | 2.18333627 |
| 50 | Absent septum pellucidum (HP:0001331) | 2.17381352 |
| 51 | Myokymia (HP:0002411) | 2.15237636 |
| 52 | Abnormal number of incisors (HP:0011064) | 2.13965940 |
| 53 | Abnormality of renal resorption (HP:0011038) | 2.13397641 |
| 54 | Lethargy (HP:0001254) | 2.12149008 |
| 55 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.10786544 |
| 56 | Maternal diabetes (HP:0009800) | 2.09538050 |
| 57 | Exercise intolerance (HP:0003546) | 2.07679069 |
| 58 | Combined immunodeficiency (HP:0005387) | 2.05102955 |
| 59 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.04368930 |
| 60 | Increased muscle lipid content (HP:0009058) | 2.03549050 |
| 61 | Hypoplasia of the pons (HP:0012110) | 2.03382863 |
| 62 | Thyroiditis (HP:0100646) | 2.02159603 |
| 63 | Panhypogammaglobulinemia (HP:0003139) | 2.01582912 |
| 64 | Respiratory difficulties (HP:0002880) | 2.01468082 |
| 65 | Chronic sinusitis (HP:0011109) | 2.01142236 |
| 66 | Methylmalonic aciduria (HP:0012120) | 1.99728343 |
| 67 | Oral leukoplakia (HP:0002745) | 1.99474167 |
| 68 | Congenital stationary night blindness (HP:0007642) | 1.97632686 |
| 69 | Sclerocornea (HP:0000647) | 1.96743134 |
| 70 | Absent thumb (HP:0009777) | 1.93311892 |
| 71 | Abnormality of the pons (HP:0007361) | 1.90730015 |
| 72 | Optic nerve hypoplasia (HP:0000609) | 1.90272321 |
| 73 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.86826685 |
| 74 | Microvesicular hepatic steatosis (HP:0001414) | 1.86479291 |
| 75 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.86411152 |
| 76 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.86411152 |
| 77 | Chronic hepatic failure (HP:0100626) | 1.85971744 |
| 78 | Glycosuria (HP:0003076) | 1.84879263 |
| 79 | Abnormality of urine glucose concentration (HP:0011016) | 1.84879263 |
| 80 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.84855684 |
| 81 | Male pseudohermaphroditism (HP:0000037) | 1.83681567 |
| 82 | Medial flaring of the eyebrow (HP:0010747) | 1.81928191 |
| 83 | Pancytopenia (HP:0001876) | 1.80854574 |
| 84 | Constricted visual fields (HP:0001133) | 1.80852692 |
| 85 | Hyperglycinuria (HP:0003108) | 1.79914918 |
| 86 | Attenuation of retinal blood vessels (HP:0007843) | 1.74801450 |
| 87 | Anencephaly (HP:0002323) | 1.73466234 |
| 88 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.70885990 |
| 89 | X-linked dominant inheritance (HP:0001423) | 1.70321421 |
| 90 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.70308166 |
| 91 | Hyperphosphaturia (HP:0003109) | 1.70027434 |
| 92 | Sensory axonal neuropathy (HP:0003390) | 1.69942758 |
| 93 | Cleft eyelid (HP:0000625) | 1.68607549 |
| 94 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.68513357 |
| 95 | Abnormality of glycine metabolism (HP:0010895) | 1.68513357 |
| 96 | Abnormality of serum amino acid levels (HP:0003112) | 1.67699226 |
| 97 | Abnormality of the ileum (HP:0001549) | 1.65762891 |
| 98 | Bile duct proliferation (HP:0001408) | 1.65248778 |
| 99 | Abnormal biliary tract physiology (HP:0012439) | 1.65248778 |
| 100 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.65037179 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.69658542 |
| 2 | MAP3K12 | 3.74105837 |
| 3 | VRK1 | 3.30194052 |
| 4 | STK16 | 2.91236218 |
| 5 | ZAK | 2.79990722 |
| 6 | TAF1 | 2.73194738 |
| 7 | WNK4 | 2.51423442 |
| 8 | WNK3 | 2.38344124 |
| 9 | TLK1 | 2.34409117 |
| 10 | TNIK | 2.18105582 |
| 11 | SRPK1 | 2.08636660 |
| 12 | NUAK1 | 2.05543276 |
| 13 | CDC7 | 2.03420318 |
| 14 | DYRK2 | 2.02798467 |
| 15 | STK39 | 1.86050747 |
| 16 | PASK | 1.79233026 |
| 17 | MAPK15 | 1.77028444 |
| 18 | ADRBK2 | 1.75960051 |
| 19 | EIF2AK3 | 1.75158909 |
| 20 | NME1 | 1.75016992 |
| 21 | MKNK2 | 1.69227023 |
| 22 | PLK3 | 1.62262562 |
| 23 | PNCK | 1.56175234 |
| 24 | MST4 | 1.55256211 |
| 25 | BUB1 | 1.47793089 |
| 26 | MAP3K11 | 1.41872200 |
| 27 | DYRK3 | 1.41745678 |
| 28 | PLK4 | 1.40315784 |
| 29 | KDR | 1.37547794 |
| 30 | BMPR1B | 1.35066451 |
| 31 | PLK2 | 1.32004526 |
| 32 | GRK1 | 1.29258117 |
| 33 | CDK19 | 1.28732290 |
| 34 | TSSK6 | 1.28559349 |
| 35 | BCKDK | 1.22808581 |
| 36 | OXSR1 | 1.17243657 |
| 37 | MKNK1 | 1.09683553 |
| 38 | WEE1 | 1.03340674 |
| 39 | TESK2 | 1.02083839 |
| 40 | PRKCG | 1.01717767 |
| 41 | EPHB2 | 0.96692471 |
| 42 | NEK1 | 0.94637888 |
| 43 | MAPKAPK5 | 0.86712840 |
| 44 | MAP2K4 | 0.85187280 |
| 45 | CSNK2A2 | 0.85089241 |
| 46 | PLK1 | 0.84296647 |
| 47 | AURKB | 0.81968818 |
| 48 | RPS6KA4 | 0.79861481 |
| 49 | EIF2AK1 | 0.79674996 |
| 50 | PBK | 0.79324804 |
| 51 | RPS6KA5 | 0.78901826 |
| 52 | MAP4K2 | 0.73770811 |
| 53 | TXK | 0.69636345 |
| 54 | CSNK2A1 | 0.67896727 |
| 55 | TGFBR1 | 0.65954695 |
| 56 | MAP2K7 | 0.65125120 |
| 57 | TRIM28 | 0.63833107 |
| 58 | PRKCI | 0.62772799 |
| 59 | AURKA | 0.62207401 |
| 60 | SIK2 | 0.61643698 |
| 61 | MAP3K4 | 0.60621969 |
| 62 | CDK8 | 0.58875060 |
| 63 | MARK1 | 0.58496194 |
| 64 | INSRR | 0.57946836 |
| 65 | MAPK13 | 0.57560485 |
| 66 | NEK2 | 0.57530596 |
| 67 | CASK | 0.56124152 |
| 68 | EIF2AK2 | 0.55892461 |
| 69 | PINK1 | 0.55796174 |
| 70 | PHKG2 | 0.55004346 |
| 71 | PHKG1 | 0.55004346 |
| 72 | MINK1 | 0.53127545 |
| 73 | CSNK1E | 0.52680004 |
| 74 | TAOK3 | 0.50556447 |
| 75 | DYRK1A | 0.50030772 |
| 76 | FRK | 0.49875733 |
| 77 | WNK1 | 0.49629572 |
| 78 | ATR | 0.49223137 |
| 79 | ACVR1B | 0.41652159 |
| 80 | CHEK2 | 0.40448520 |
| 81 | PRKCE | 0.40240024 |
| 82 | TIE1 | 0.39547198 |
| 83 | DAPK3 | 0.38824697 |
| 84 | STK24 | 0.37456406 |
| 85 | CSNK1A1 | 0.36538635 |
| 86 | PRKACA | 0.36475686 |
| 87 | PRKG1 | 0.36462307 |
| 88 | LRRK2 | 0.36414049 |
| 89 | PIM1 | 0.34908030 |
| 90 | CDK9 | 0.34298802 |
| 91 | SGK1 | 0.33156163 |
| 92 | STK38L | 0.33009822 |
| 93 | CDK3 | 0.31947120 |
| 94 | STK11 | 0.31179406 |
| 95 | PRKCQ | 0.30841021 |
| 96 | CDK7 | 0.30705546 |
| 97 | ADRBK1 | 0.30090635 |
| 98 | ALK | 0.30011859 |
| 99 | ABL2 | 0.28171702 |
| 100 | ATM | 0.26995658 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.02614301 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.69051207 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.02947336 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.88673921 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.81560142 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.79520225 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.72968586 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.62584932 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.47515176 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.46457982 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.24028555 |
| 12 | DNA replication_Homo sapiens_hsa03030 | 2.20992118 |
| 13 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.15927099 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.12579690 |
| 15 | Mismatch repair_Homo sapiens_hsa03430 | 2.03131682 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.98663553 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.89999182 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.87572251 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.79872032 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.69511301 |
| 21 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.48864452 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.42215923 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.37888229 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.35686435 |
| 25 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.35575236 |
| 26 | RNA transport_Homo sapiens_hsa03013 | 1.34332804 |
| 27 | Base excision repair_Homo sapiens_hsa03410 | 1.33531654 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30704347 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.26910399 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.23757836 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.14966405 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.11729846 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.10511095 |
| 34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.09790363 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 0.96363005 |
| 36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.95378485 |
| 37 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.95031752 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.92097666 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.91355523 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 0.86320276 |
| 41 | Allograft rejection_Homo sapiens_hsa05330 | 0.76354315 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.74560667 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73360636 |
| 44 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.72872537 |
| 45 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.72677332 |
| 46 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.72188485 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.71865363 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70179124 |
| 49 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69767996 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.69587682 |
| 51 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68420886 |
| 52 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.68299218 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.68208948 |
| 54 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.67827900 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.66742062 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.65861291 |
| 57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.63591730 |
| 58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.63076689 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.59900248 |
| 60 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.58612052 |
| 61 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.56199390 |
| 62 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.54109718 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52661555 |
| 64 | Sulfur relay system_Homo sapiens_hsa04122 | 0.51229422 |
| 65 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.49575098 |
| 66 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.49197308 |
| 67 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.49000557 |
| 68 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.48702905 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.48429463 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.48206679 |
| 71 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.46568639 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45272179 |
| 73 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44611542 |
| 74 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44576299 |
| 75 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.42100036 |
| 76 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.41087666 |
| 77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37591347 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35838930 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33306944 |
| 80 | Cell cycle_Homo sapiens_hsa04110 | 0.32940032 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.32033424 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30442819 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30072745 |
| 84 | Morphine addiction_Homo sapiens_hsa05032 | 0.29419581 |
| 85 | Taste transduction_Homo sapiens_hsa04742 | 0.25751916 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24221970 |
| 87 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.23430550 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.22578865 |
| 89 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.20900699 |
| 90 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.19336140 |
| 91 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.17879695 |
| 92 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.17531381 |
| 93 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.17393484 |
| 94 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.16417684 |
| 95 | Mineral absorption_Homo sapiens_hsa04978 | 0.14638732 |
| 96 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.13735057 |
| 97 | Carbon metabolism_Homo sapiens_hsa01200 | 0.12575684 |
| 98 | Alcoholism_Homo sapiens_hsa05034 | 0.12364703 |
| 99 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.11843772 |
| 100 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.11804434 |

