

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | interleukin-6-mediated signaling pathway (GO:0070102) | 8.45742269 |
| 2 | galactose catabolic process (GO:0019388) | 7.57598881 |
| 3 | fat-soluble vitamin catabolic process (GO:0042363) | 7.30278039 |
| 4 | vitamin catabolic process (GO:0009111) | 7.30278039 |
| 5 | centriole replication (GO:0007099) | 5.43176303 |
| 6 | rRNA methylation (GO:0031167) | 5.27966570 |
| 7 | sperm motility (GO:0030317) | 5.22816443 |
| 8 | single strand break repair (GO:0000012) | 5.19804679 |
| 9 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 5.00425527 |
| 10 | phosphate ion homeostasis (GO:0055062) | 4.97210933 |
| 11 | trivalent inorganic anion homeostasis (GO:0072506) | 4.97210933 |
| 12 | microtubule depolymerization (GO:0007019) | 4.95925596 |
| 13 | positive regulation of T cell cytokine production (GO:0002726) | 4.74062874 |
| 14 | rRNA modification (GO:0000154) | 4.71891793 |
| 15 | chromosome condensation (GO:0030261) | 4.59083023 |
| 16 | response to pheromone (GO:0019236) | 4.56497476 |
| 17 | regulation of translational termination (GO:0006449) | 4.54203853 |
| 18 | vitamin D metabolic process (GO:0042359) | 4.48767582 |
| 19 | cellular anion homeostasis (GO:0030002) | 4.48365162 |
| 20 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 4.43294030 |
| 21 | centriole assembly (GO:0098534) | 4.42625970 |
| 22 | DNA packaging (GO:0006323) | 4.38285247 |
| 23 | microtubule polymerization or depolymerization (GO:0031109) | 4.33996134 |
| 24 | ribosomal large subunit biogenesis (GO:0042273) | 4.27679287 |
| 25 | regulation of histone H3-K9 methylation (GO:0051570) | 4.25323359 |
| 26 | regulation of DNA endoreduplication (GO:0032875) | 4.16850066 |
| 27 | histone exchange (GO:0043486) | 4.14179085 |
| 28 | acrosome reaction (GO:0007340) | 4.13686697 |
| 29 | negative regulation of histone methylation (GO:0031061) | 4.12424082 |
| 30 | galactose metabolic process (GO:0006012) | 4.05854212 |
| 31 | positive regulation of T-helper 1 type immune response (GO:0002827) | 4.01107001 |
| 32 | DNA topological change (GO:0006265) | 4.00351420 |
| 33 | protein-cofactor linkage (GO:0018065) | 3.99297652 |
| 34 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.99225759 |
| 35 | spermatid nucleus differentiation (GO:0007289) | 3.93086589 |
| 36 | interferon-gamma production (GO:0032609) | 3.90479762 |
| 37 | regulation of T cell chemotaxis (GO:0010819) | 3.88976025 |
| 38 | positive regulation of T cell chemotaxis (GO:0010820) | 3.88976025 |
| 39 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.87186008 |
| 40 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.83820338 |
| 41 | spermatid development (GO:0007286) | 3.77629950 |
| 42 | cellular response to interleukin-6 (GO:0071354) | 3.77014246 |
| 43 | axonemal dynein complex assembly (GO:0070286) | 3.76787565 |
| 44 | regulation of translational elongation (GO:0006448) | 3.71917013 |
| 45 | mitotic G2 DNA damage checkpoint (GO:0007095) | 3.70995015 |
| 46 | positive regulation of type 2 immune response (GO:0002830) | 3.60845955 |
| 47 | protein targeting to Golgi (GO:0000042) | 3.58374241 |
| 48 | CENP-A containing nucleosome assembly (GO:0034080) | 3.57745227 |
| 49 | establishment of protein localization to Golgi (GO:0072600) | 3.57275839 |
| 50 | negative regulation of gene silencing (GO:0060969) | 3.53536730 |
| 51 | sperm capacitation (GO:0048240) | 3.47865038 |
| 52 | mitotic G2/M transition checkpoint (GO:0044818) | 3.46716241 |
| 53 | apoptotic DNA fragmentation (GO:0006309) | 3.43053160 |
| 54 | rRNA catabolic process (GO:0016075) | 3.42957706 |
| 55 | negative regulation of bone mineralization (GO:0030502) | 3.39538220 |
| 56 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 3.37232931 |
| 57 | regulation of gene silencing by RNA (GO:0060966) | 3.35670373 |
| 58 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.35670373 |
| 59 | regulation of gene silencing by miRNA (GO:0060964) | 3.35670373 |
| 60 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.33394752 |
| 61 | chromatin remodeling at centromere (GO:0031055) | 3.32742000 |
| 62 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.32688036 |
| 63 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.30064412 |
| 64 | termination of RNA polymerase III transcription (GO:0006386) | 3.30064412 |
| 65 | multicellular organism reproduction (GO:0032504) | 3.29423294 |
| 66 | folic acid transport (GO:0015884) | 3.25488470 |
| 67 | negative regulation of T cell mediated immunity (GO:0002710) | 3.25029790 |
| 68 | maturation of SSU-rRNA (GO:0030490) | 3.19622806 |
| 69 | regulation of transcription elongation from RNA polymerase II promoter (GO:0034243) | 3.12158703 |
| 70 | regulation of centriole replication (GO:0046599) | 3.10618136 |
| 71 | sperm-egg recognition (GO:0035036) | 3.09282541 |
| 72 | lymphocyte chemotaxis (GO:0048247) | 3.08668155 |
| 73 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 3.08043272 |
| 74 | nucleosome disassembly (GO:0006337) | 3.07772399 |
| 75 | protein-DNA complex disassembly (GO:0032986) | 3.07772399 |
| 76 | regulation of mesoderm development (GO:2000380) | 3.06203305 |
| 77 | response to interleukin-6 (GO:0070741) | 2.98762636 |
| 78 | protein localization to Golgi apparatus (GO:0034067) | 2.94375941 |
| 79 | response to redox state (GO:0051775) | 2.90944017 |
| 80 | epithelial cilium movement (GO:0003351) | 2.87886108 |
| 81 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.87598635 |
| 82 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.85745791 |
| 83 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.84870568 |
| 84 | DNA replication-independent nucleosome organization (GO:0034724) | 2.84870568 |
| 85 | phosphorelay signal transduction system (GO:0000160) | 2.83889760 |
| 86 | negative regulation of inclusion body assembly (GO:0090084) | 2.83398464 |
| 87 | negative regulation of biomineral tissue development (GO:0070168) | 2.82838117 |
| 88 | inner mitochondrial membrane organization (GO:0007007) | 2.81677429 |
| 89 | positive regulation of DNA-templated transcription, elongation (GO:0032786) | 2.81284105 |
| 90 | regulation of T cell cytokine production (GO:0002724) | 2.80960950 |
| 91 | protein polyglutamylation (GO:0018095) | 2.79520246 |
| 92 | reproduction (GO:0000003) | 2.78630659 |
| 93 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.78425373 |
| 94 | NADH dehydrogenase complex assembly (GO:0010257) | 2.78425373 |
| 95 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.78425373 |
| 96 | telomere maintenance via telomerase (GO:0007004) | 2.78142892 |
| 97 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.77803101 |
| 98 | chromatin silencing (GO:0006342) | 2.77341937 |
| 99 | regulation of establishment of cell polarity (GO:2000114) | 2.76842768 |
| 100 | male meiosis I (GO:0007141) | 2.74628592 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 4.15469414 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.85523185 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.46950353 |
| 4 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.27002280 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.09451897 |
| 6 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.99769384 |
| 7 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 2.99769384 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.77962837 |
| 9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.74286816 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.49595429 |
| 11 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.36890758 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.30973646 |
| 13 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.30808433 |
| 14 | FUS_26573619_Chip-Seq_HEK293_Human | 2.25985063 |
| 15 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.07951110 |
| 16 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.03371737 |
| 17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.02182788 |
| 18 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.91419994 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.85642197 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.85486234 |
| 21 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.84590983 |
| 22 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.84027047 |
| 23 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.76916496 |
| 24 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.76916496 |
| 25 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.76669084 |
| 26 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.76624758 |
| 27 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.73597195 |
| 28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.70779386 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.69154330 |
| 30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.67101434 |
| 31 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.66832413 |
| 32 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.62740500 |
| 33 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.59883390 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.58246109 |
| 35 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.51192569 |
| 36 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.51021078 |
| 37 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.45825738 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.42738570 |
| 39 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.40520843 |
| 40 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.36145700 |
| 41 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.35991148 |
| 42 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.35608229 |
| 43 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.34381099 |
| 44 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.32956624 |
| 45 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.31475896 |
| 46 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.30424438 |
| 47 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28802816 |
| 48 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28802816 |
| 49 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.26203126 |
| 50 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.25811769 |
| 51 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.24547537 |
| 52 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.23662225 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.22709665 |
| 54 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22410707 |
| 55 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.22332006 |
| 56 | NFYB_21822215_ChIP-Seq_K562_Human | 1.21351777 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21066299 |
| 58 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.20313434 |
| 59 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.20216317 |
| 60 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.19889411 |
| 61 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18511864 |
| 62 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.16611786 |
| 63 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.16539514 |
| 64 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.16231797 |
| 65 | AR_25329375_ChIP-Seq_VCAP_Human | 1.16122569 |
| 66 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.16036872 |
| 67 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14517037 |
| 68 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.13461613 |
| 69 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.11781812 |
| 70 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.11298804 |
| 71 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.11149424 |
| 72 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.10795566 |
| 73 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.10649553 |
| 74 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.10649553 |
| 75 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.10649553 |
| 76 | TBL1_22424771_ChIP-Seq_293T_Human | 1.10425955 |
| 77 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.09963256 |
| 78 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.08327084 |
| 79 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.07774737 |
| 80 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.07774737 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.07089075 |
| 82 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.06452842 |
| 83 | NFYA_21822215_ChIP-Seq_K562_Human | 1.05971916 |
| 84 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.05505849 |
| 85 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.05193661 |
| 86 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.04116962 |
| 87 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04096742 |
| 88 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03979999 |
| 89 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.03260560 |
| 90 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.03235516 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02866469 |
| 92 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02577709 |
| 93 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.01593739 |
| 94 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.00600878 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.00354604 |
| 96 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.99792119 |
| 97 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98356450 |
| 98 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.97583321 |
| 99 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.96995555 |
| 100 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.96879442 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005410_abnormal_fertilization | 4.65220792 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.36406640 |
| 3 | MP0002234_abnormal_pharynx_morphology | 3.61723745 |
| 4 | MP0003646_muscle_fatigue | 3.41610108 |
| 5 | MP0001764_abnormal_homeostasis | 3.39738943 |
| 6 | MP0008877_abnormal_DNA_methylation | 3.22546292 |
| 7 | MP0002396_abnormal_hematopoietic_system | 2.93867295 |
| 8 | MP0002160_abnormal_reproductive_system | 2.91148151 |
| 9 | MP0002089_abnormal_postnatal_growth/wei | 2.69515292 |
| 10 | MP0009053_abnormal_anal_canal | 2.64785925 |
| 11 | MP0003718_maternal_effect | 2.53747884 |
| 12 | MP0003136_yellow_coat_color | 2.43545060 |
| 13 | MP0002736_abnormal_nociception_after | 2.28802235 |
| 14 | MP0003878_abnormal_ear_physiology | 2.27090577 |
| 15 | MP0005377_hearing/vestibular/ear_phenot | 2.27090577 |
| 16 | MP0001293_anophthalmia | 2.21507258 |
| 17 | MP0001542_abnormal_bone_strength | 2.16177240 |
| 18 | MP0005389_reproductive_system_phenotype | 2.14743379 |
| 19 | MP0004957_abnormal_blastocyst_morpholog | 2.12832899 |
| 20 | MP0004019_abnormal_vitamin_homeostasis | 2.09503253 |
| 21 | MP0001929_abnormal_gametogenesis | 1.98473108 |
| 22 | MP0003698_abnormal_male_reproductive | 1.97946355 |
| 23 | MP0003693_abnormal_embryo_hatching | 1.94285654 |
| 24 | MP0001968_abnormal_touch/_nociception | 1.82666907 |
| 25 | MP0004885_abnormal_endolymph | 1.79477890 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.77911016 |
| 27 | MP0005310_abnormal_salivary_gland | 1.73918276 |
| 28 | MP0009379_abnormal_foot_pigmentation | 1.46045468 |
| 29 | MP0002210_abnormal_sex_determination | 1.41913703 |
| 30 | MP0000613_abnormal_salivary_gland | 1.39984142 |
| 31 | MP0002161_abnormal_fertility/fecundity | 1.38297305 |
| 32 | MP0004742_abnormal_vestibular_system | 1.37496508 |
| 33 | MP0004142_abnormal_muscle_tone | 1.37461200 |
| 34 | MP0002909_abnormal_adrenal_gland | 1.34047606 |
| 35 | MP0000049_abnormal_middle_ear | 1.32052367 |
| 36 | MP0004043_abnormal_pH_regulation | 1.31987423 |
| 37 | MP0003315_abnormal_perineum_morphology | 1.27425515 |
| 38 | MP0010094_abnormal_chromosome_stability | 1.26920728 |
| 39 | MP0000631_abnormal_neuroendocrine_gland | 1.25488181 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.22619198 |
| 41 | MP0003938_abnormal_ear_development | 1.22527990 |
| 42 | MP0001145_abnormal_male_reproductive | 1.20509476 |
| 43 | MP0002132_abnormal_respiratory_system | 1.16588369 |
| 44 | MP0005083_abnormal_biliary_tract | 1.14698402 |
| 45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.13082531 |
| 46 | MP0002006_tumorigenesis | 1.12183875 |
| 47 | MP0002233_abnormal_nose_morphology | 1.10304859 |
| 48 | MP0003077_abnormal_cell_cycle | 1.09650444 |
| 49 | MP0002272_abnormal_nervous_system | 1.09202107 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.06080939 |
| 51 | MP0001286_abnormal_eye_development | 1.05018311 |
| 52 | MP0001188_hyperpigmentation | 1.04872811 |
| 53 | MP0000653_abnormal_sex_gland | 1.03982839 |
| 54 | MP0005084_abnormal_gallbladder_morpholo | 1.03874745 |
| 55 | MP0006072_abnormal_retinal_apoptosis | 1.03754127 |
| 56 | MP0003111_abnormal_nucleus_morphology | 1.01111103 |
| 57 | MP0003890_abnormal_embryonic-extraembry | 0.98415930 |
| 58 | MP0000026_abnormal_inner_ear | 0.97059197 |
| 59 | MP0001919_abnormal_reproductive_system | 0.95941989 |
| 60 | MP0001765_abnormal_ion_homeostasis | 0.94690416 |
| 61 | MP0003937_abnormal_limbs/digits/tail_de | 0.93369866 |
| 62 | MP0001963_abnormal_hearing_physiology | 0.88333774 |
| 63 | MP0008875_abnormal_xenobiotic_pharmacok | 0.88055912 |
| 64 | MP0002102_abnormal_ear_morphology | 0.86888567 |
| 65 | MP0002282_abnormal_trachea_morphology | 0.86408833 |
| 66 | MP0008872_abnormal_physiological_respon | 0.84993635 |
| 67 | MP0008932_abnormal_embryonic_tissue | 0.83407857 |
| 68 | MP0005551_abnormal_eye_electrophysiolog | 0.81364985 |
| 69 | MP0006036_abnormal_mitochondrial_physio | 0.79764083 |
| 70 | MP0002067_abnormal_sensory_capabilities | 0.76530003 |
| 71 | MP0000762_abnormal_tongue_morphology | 0.75261177 |
| 72 | MP0002085_abnormal_embryonic_tissue | 0.75176737 |
| 73 | MP0005376_homeostasis/metabolism_phenot | 0.73467404 |
| 74 | MP0001348_abnormal_lacrimal_gland | 0.73105697 |
| 75 | MP0003283_abnormal_digestive_organ | 0.72766924 |
| 76 | MP0000428_abnormal_craniofacial_morphol | 0.70835943 |
| 77 | MP0006035_abnormal_mitochondrial_morpho | 0.69654035 |
| 78 | MP0000778_abnormal_nervous_system | 0.68226580 |
| 79 | MP0005391_vision/eye_phenotype | 0.66233350 |
| 80 | MP0008058_abnormal_DNA_repair | 0.65402109 |
| 81 | MP0002084_abnormal_developmental_patter | 0.65199830 |
| 82 | MP0001984_abnormal_olfaction | 0.64711318 |
| 83 | MP0002177_abnormal_outer_ear | 0.63120585 |
| 84 | MP0003861_abnormal_nervous_system | 0.62554593 |
| 85 | MP0001697_abnormal_embryo_size | 0.62440319 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.61987092 |
| 87 | MP0001486_abnormal_startle_reflex | 0.61876379 |
| 88 | MP0000955_abnormal_spinal_cord | 0.60764506 |
| 89 | MP0003755_abnormal_palate_morphology | 0.60646269 |
| 90 | MP0003119_abnormal_digestive_system | 0.59735557 |
| 91 | MP0002752_abnormal_somatic_nervous | 0.58415309 |
| 92 | MP0000566_synostosis | 0.57799436 |
| 93 | MP0002733_abnormal_thermal_nociception | 0.56454343 |
| 94 | MP0009745_abnormal_behavioral_response | 0.55792250 |
| 95 | MP0002138_abnormal_hepatobiliary_system | 0.55681990 |
| 96 | MP0005253_abnormal_eye_physiology | 0.55566694 |
| 97 | MP0005379_endocrine/exocrine_gland_phen | 0.54973195 |
| 98 | MP0008789_abnormal_olfactory_epithelium | 0.53098598 |
| 99 | MP0005395_other_phenotype | 0.51695645 |
| 100 | MP0008057_abnormal_DNA_replication | 0.51053566 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteomalacia (HP:0002749) | 7.29014028 |
| 2 | Premature ovarian failure (HP:0008209) | 4.95837871 |
| 3 | Abnormality of the labia minora (HP:0012880) | 4.81335811 |
| 4 | Vascular calcification (HP:0004934) | 4.41147840 |
| 5 | Septo-optic dysplasia (HP:0100842) | 3.93945930 |
| 6 | Abnormality of renal resorption (HP:0011038) | 3.92724688 |
| 7 | Cardiovascular calcification (HP:0011915) | 3.82827949 |
| 8 | Hypergonadotropic hypogonadism (HP:0000815) | 3.70314942 |
| 9 | Absent/shortened dynein arms (HP:0200106) | 3.68407250 |
| 10 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.68407250 |
| 11 | Retrobulbar optic neuritis (HP:0100654) | 3.56484803 |
| 12 | Optic neuritis (HP:0100653) | 3.56484803 |
| 13 | Abnormal number of erythroid precursors (HP:0012131) | 3.56357242 |
| 14 | Hyperphosphatemia (HP:0002905) | 3.38047272 |
| 15 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.25756062 |
| 16 | Hypoplastic ischia (HP:0003175) | 3.14120369 |
| 17 | Abnormal ciliary motility (HP:0012262) | 2.82017876 |
| 18 | Abnormal urine phosphate concentration (HP:0012599) | 2.77886469 |
| 19 | Orchitis (HP:0100796) | 2.75951923 |
| 20 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.75072042 |
| 21 | Chromsome breakage (HP:0040012) | 2.73134570 |
| 22 | Spinal canal stenosis (HP:0003416) | 2.68471702 |
| 23 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.65200048 |
| 24 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.65200048 |
| 25 | Severe visual impairment (HP:0001141) | 2.63051686 |
| 26 | Sensory axonal neuropathy (HP:0003390) | 2.58194213 |
| 27 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.57904584 |
| 28 | Abnormality of the ischium (HP:0003174) | 2.56851132 |
| 29 | Abnormality of renal excretion (HP:0011036) | 2.52736209 |
| 30 | Optic nerve hypoplasia (HP:0000609) | 2.49084080 |
| 31 | Maternal diabetes (HP:0009800) | 2.48655139 |
| 32 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.48344026 |
| 33 | Abnormality of lateral ventricle (HP:0030047) | 2.46122421 |
| 34 | Patellar aplasia (HP:0006443) | 2.46005742 |
| 35 | Acute necrotizing encephalopathy (HP:0006965) | 2.42068863 |
| 36 | Absent septum pellucidum (HP:0001331) | 2.40931508 |
| 37 | Volvulus (HP:0002580) | 2.38732866 |
| 38 | Nephronophthisis (HP:0000090) | 2.38476703 |
| 39 | Abnormality of permanent molar morphology (HP:0011071) | 2.29936347 |
| 40 | Abnormality of the dental root (HP:0006486) | 2.29936347 |
| 41 | Taurodontia (HP:0000679) | 2.29936347 |
| 42 | Rickets (HP:0002748) | 2.20415210 |
| 43 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.18507894 |
| 44 | Keratoconjunctivitis sicca (HP:0001097) | 2.17349772 |
| 45 | Acute encephalopathy (HP:0006846) | 2.15313453 |
| 46 | Congenital stationary night blindness (HP:0007642) | 2.12375714 |
| 47 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.09951392 |
| 48 | Abnormality of molar morphology (HP:0011070) | 2.09233666 |
| 49 | Abnormality of molar (HP:0011077) | 2.09233666 |
| 50 | Myositis (HP:0100614) | 2.08708683 |
| 51 | Reticulocytopenia (HP:0001896) | 2.08558769 |
| 52 | Abnormality of the dental pulp (HP:0006479) | 2.07811764 |
| 53 | Mitochondrial inheritance (HP:0001427) | 2.06316242 |
| 54 | Molar tooth sign on MRI (HP:0002419) | 2.01710859 |
| 55 | Abnormality of midbrain morphology (HP:0002418) | 2.01710859 |
| 56 | Macrocytic anemia (HP:0001972) | 2.01457380 |
| 57 | Chronic hepatic failure (HP:0100626) | 10.8763836 |
| 58 | Keratoconjunctivitis (HP:0001096) | 1.98010923 |
| 59 | Abnormality of placental membranes (HP:0011409) | 1.96499529 |
| 60 | Amniotic constriction ring (HP:0009775) | 1.96499529 |
| 61 | Abnormality of DNA repair (HP:0003254) | 1.95048296 |
| 62 | Azoospermia (HP:0000027) | 1.93619634 |
| 63 | Hemoptysis (HP:0002105) | 1.92931045 |
| 64 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.92725074 |
| 65 | Rectal fistula (HP:0100590) | 1.92673852 |
| 66 | Rectovaginal fistula (HP:0000143) | 1.92673852 |
| 67 | Oligodontia (HP:0000677) | 1.91549713 |
| 68 | Impulsivity (HP:0100710) | 1.91443734 |
| 69 | Abnormality of the septum pellucidum (HP:0007375) | 1.88603481 |
| 70 | Cerebral hypomyelination (HP:0006808) | 1.88136411 |
| 71 | Tubular atrophy (HP:0000092) | 1.88115391 |
| 72 | Increased hepatocellular lipid droplets (HP:0006565) | 1.87033127 |
| 73 | 3-Methylglutaconic aciduria (HP:0003535) | 1.86608658 |
| 74 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.86460035 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.85320227 |
| 76 | Birth length less than 3rd percentile (HP:0003561) | 1.83559355 |
| 77 | Type II lissencephaly (HP:0007260) | 1.82505180 |
| 78 | Attenuation of retinal blood vessels (HP:0007843) | 1.79247044 |
| 79 | Anophthalmia (HP:0000528) | 1.78075986 |
| 80 | Sparse scalp hair (HP:0002209) | 1.77720972 |
| 81 | Multiple enchondromatosis (HP:0005701) | 1.75203735 |
| 82 | Duplicated collecting system (HP:0000081) | 1.74281836 |
| 83 | Hepatocellular necrosis (HP:0001404) | 1.73213111 |
| 84 | Pallor (HP:0000980) | 1.72153751 |
| 85 | Progressive sensorineural hearing impairment (HP:0000408) | 1.72025489 |
| 86 | Abnormal number of incisors (HP:0011064) | 1.70734683 |
| 87 | Progressive macrocephaly (HP:0004481) | 1.70630483 |
| 88 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.69949671 |
| 89 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.69157067 |
| 90 | Abnormal spermatogenesis (HP:0008669) | 1.67485031 |
| 91 | Increased CSF lactate (HP:0002490) | 1.67438619 |
| 92 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.66262203 |
| 93 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.65666870 |
| 94 | Impaired smooth pursuit (HP:0007772) | 1.64994113 |
| 95 | Menstrual irregularities (HP:0000858) | 1.64284706 |
| 96 | Infertility (HP:0000789) | 1.63834706 |
| 97 | Renal Fanconi syndrome (HP:0001994) | 1.62390244 |
| 98 | Abnormality of the renal collecting system (HP:0004742) | 1.61596948 |
| 99 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.61426396 |
| 100 | Genetic anticipation (HP:0003743) | 1.61278814 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 5.90926474 |
| 2 | PLK4 | 5.19237092 |
| 3 | NEK9 | 3.75696423 |
| 4 | CDK12 | 3.33788359 |
| 5 | CDC7 | 3.22604907 |
| 6 | PNCK | 2.59964327 |
| 7 | CDK19 | 2.46193153 |
| 8 | BRD4 | 2.37339292 |
| 9 | PLK2 | 2.17505739 |
| 10 | WNK4 | 2.13725652 |
| 11 | MAPKAPK5 | 1.97416505 |
| 12 | STK39 | 1.86046576 |
| 13 | DYRK3 | 1.73492180 |
| 14 | TLK1 | 1.68161483 |
| 15 | MST4 | 1.66466148 |
| 16 | VRK1 | 1.51448894 |
| 17 | DDR2 | 1.49009861 |
| 18 | VRK2 | 1.47029354 |
| 19 | NEK2 | 1.42198126 |
| 20 | TSSK6 | 1.37836381 |
| 21 | NME1 | 1.36204401 |
| 22 | BMPR1B | 1.35210531 |
| 23 | OXSR1 | 1.33702801 |
| 24 | STK16 | 1.31829727 |
| 25 | INSRR | 1.29675924 |
| 26 | TNIK | 1.26872581 |
| 27 | DYRK1B | 1.24944256 |
| 28 | MKNK2 | 1.24404245 |
| 29 | PLK1 | 1.22617121 |
| 30 | IRAK1 | 1.20102930 |
| 31 | SRPK1 | 1.14787650 |
| 32 | PLK3 | 1.14118654 |
| 33 | MAPK15 | 1.13821488 |
| 34 | NLK | 1.11671228 |
| 35 | SGK2 | 1.11540910 |
| 36 | TAF1 | 1.11286941 |
| 37 | LATS2 | 1.10136565 |
| 38 | CDK7 | 1.07548786 |
| 39 | SGK223 | 1.04580371 |
| 40 | SGK494 | 1.04580371 |
| 41 | MKNK1 | 0.95848194 |
| 42 | WNK1 | 0.95796532 |
| 43 | NUAK1 | 0.94839878 |
| 44 | TESK1 | 0.91546632 |
| 45 | STK38L | 0.91024575 |
| 46 | NEK1 | 0.86986458 |
| 47 | CDK8 | 0.81897661 |
| 48 | EEF2K | 0.81188826 |
| 49 | CDK3 | 0.79885976 |
| 50 | ACVR1B | 0.77586242 |
| 51 | ZAK | 0.76420560 |
| 52 | DYRK2 | 0.75414790 |
| 53 | AURKB | 0.74434333 |
| 54 | CAMK1G | 0.72657158 |
| 55 | CHEK1 | 0.70728130 |
| 56 | AURKA | 0.69769392 |
| 57 | MAP2K7 | 0.69574980 |
| 58 | MAP4K2 | 0.68414729 |
| 59 | ALK | 0.66426324 |
| 60 | PRKCG | 0.65267486 |
| 61 | BRSK2 | 0.64908363 |
| 62 | RPS6KA5 | 0.62347646 |
| 63 | TTK | 0.62266756 |
| 64 | CSNK1E | 0.60647845 |
| 65 | SGK1 | 0.60327669 |
| 66 | CHEK2 | 0.60102244 |
| 67 | MAP3K4 | 0.59853595 |
| 68 | AKT3 | 0.59792055 |
| 69 | CSNK2A1 | 0.59682795 |
| 70 | PIK3CG | 0.58801722 |
| 71 | PINK1 | 0.57258455 |
| 72 | CDK1 | 0.57061909 |
| 73 | EPHB2 | 0.56792448 |
| 74 | CDK2 | 0.55602065 |
| 75 | EIF2AK3 | 0.54066027 |
| 76 | MAPKAPK3 | 0.53870164 |
| 77 | CSNK2A2 | 0.51544269 |
| 78 | ADRBK2 | 0.51425108 |
| 79 | UHMK1 | 0.49740099 |
| 80 | BCKDK | 0.46857648 |
| 81 | MAPK14 | 0.46841922 |
| 82 | TYRO3 | 0.45263901 |
| 83 | RPS6KB2 | 0.45097343 |
| 84 | PRKG1 | 0.42577454 |
| 85 | JAK3 | 0.42012002 |
| 86 | ABL2 | 0.41535482 |
| 87 | ATM | 0.41381340 |
| 88 | CAMK1D | 0.40066694 |
| 89 | CDK9 | 0.39114452 |
| 90 | WNK3 | 0.38068641 |
| 91 | RPS6KA4 | 0.36434510 |
| 92 | DMPK | 0.35952741 |
| 93 | RPS6KA1 | 0.35780753 |
| 94 | GSK3B | 0.35539710 |
| 95 | ATR | 0.34265266 |
| 96 | BRAF | 0.32526125 |
| 97 | WEE1 | 0.32182167 |
| 98 | STK11 | 0.31060815 |
| 99 | PDK2 | 0.30710465 |
| 100 | PRKCQ | 0.27684324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Homologous recombination_Homo sapiens_hsa03440 | 3.95488509 |
| 2 | RNA polymerase_Homo sapiens_hsa03020 | 3.85717308 |
| 3 | Basal transcription factors_Homo sapiens_hsa03022 | 3.70099098 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.87982158 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.70247742 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.61907528 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.53295505 |
| 8 | Sulfur relay system_Homo sapiens_hsa04122 | 2.35448693 |
| 9 | Spliceosome_Homo sapiens_hsa03040 | 2.26142554 |
| 10 | DNA replication_Homo sapiens_hsa03030 | 2.22190454 |
| 11 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.06551212 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.00715561 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 1.89669039 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.86495363 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.80669930 |
| 16 | Olfactory transduction_Homo sapiens_hsa04740 | 1.76721555 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.67313788 |
| 18 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.62898980 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.60398981 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.59019858 |
| 21 | Proteasome_Homo sapiens_hsa03050 | 1.57802189 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.52867474 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.52497762 |
| 24 | Parkinsons disease_Homo sapiens_hsa05012 | 1.48904906 |
| 25 | Allograft rejection_Homo sapiens_hsa05330 | 1.48289615 |
| 26 | Galactose metabolism_Homo sapiens_hsa00052 | 1.47913213 |
| 27 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.39916513 |
| 28 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.37385248 |
| 29 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.35773107 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.32087018 |
| 31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.23314493 |
| 32 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.23027727 |
| 33 | RNA degradation_Homo sapiens_hsa03018 | 1.22892385 |
| 34 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.21994986 |
| 35 | Nicotine addiction_Homo sapiens_hsa05033 | 1.21408921 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.21145201 |
| 37 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.19524096 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.15244425 |
| 39 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.11285773 |
| 40 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.09713358 |
| 41 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.08899389 |
| 42 | Base excision repair_Homo sapiens_hsa03410 | 1.07246233 |
| 43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.04775019 |
| 44 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.04508220 |
| 45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.00002877 |
| 46 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.99310331 |
| 47 | Melanoma_Homo sapiens_hsa05218 | 0.96994228 |
| 48 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.96406742 |
| 49 | Alzheimers disease_Homo sapiens_hsa05010 | 0.94570178 |
| 50 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.91425631 |
| 51 | Cell cycle_Homo sapiens_hsa04110 | 0.91072717 |
| 52 | Taste transduction_Homo sapiens_hsa04742 | 0.88014175 |
| 53 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.86650049 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83814688 |
| 55 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.83754113 |
| 56 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.83378804 |
| 57 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.82976949 |
| 58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.82548220 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78340332 |
| 60 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.78280811 |
| 61 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.74857559 |
| 62 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.72693546 |
| 63 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.66898628 |
| 64 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.66876178 |
| 65 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.66615039 |
| 66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.66492097 |
| 67 | Lysine degradation_Homo sapiens_hsa00310 | 0.64321472 |
| 68 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.60806305 |
| 69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.60078240 |
| 70 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.58364975 |
| 71 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.55666890 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53838004 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52782646 |
| 74 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.49410311 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.49360817 |
| 76 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.49059620 |
| 77 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46253739 |
| 78 | Viral myocarditis_Homo sapiens_hsa05416 | 0.45546829 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.43382057 |
| 80 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.41970028 |
| 81 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.40227703 |
| 82 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39469115 |
| 83 | Metabolic pathways_Homo sapiens_hsa01100 | 0.38972039 |
| 84 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.38793442 |
| 85 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38423872 |
| 86 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.38388473 |
| 87 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.38260770 |
| 88 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.38155823 |
| 89 | Morphine addiction_Homo sapiens_hsa05032 | 0.37665021 |
| 90 | Mineral absorption_Homo sapiens_hsa04978 | 0.37425198 |
| 91 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.37312020 |
| 92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.36132946 |
| 93 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.33294693 |
| 94 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.30694413 |
| 95 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.30391008 |
| 96 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.30289005 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.28992961 |
| 98 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.27732886 |
| 99 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.26113844 |
| 100 | Histidine metabolism_Homo sapiens_hsa00340 | 0.24523025 |

