YBX3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-mediated cell contraction (GO:0070252)7.13220706
2sarcoplasmic reticulum calcium ion transport (GO:0070296)6.87701980
3skeletal muscle contraction (GO:0003009)6.59071907
4fusion of sperm to egg plasma membrane (GO:0007342)5.78837933
5regulation of skeletal muscle contraction (GO:0014819)5.77547547
6actin filament-based movement (GO:0030048)5.55809693
7myofibril assembly (GO:0030239)5.34570994
8sperm-egg recognition (GO:0035036)5.30653190
9sarcomere organization (GO:0045214)5.22150725
10cilium or flagellum-dependent cell motility (GO:0001539)5.17025492
11binding of sperm to zona pellucida (GO:0007339)5.08622364
12creatine metabolic process (GO:0006600)5.03626065
13striated muscle contraction (GO:0006941)4.91670961
14cell wall macromolecule metabolic process (GO:0044036)4.84379789
15cell wall macromolecule catabolic process (GO:0016998)4.84379789
16nuclear pore complex assembly (GO:0051292)4.80378252
17response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.77083682
18sperm motility (GO:0030317)4.76717889
19skeletal muscle adaptation (GO:0043501)4.74398433
20cell-cell recognition (GO:0009988)4.71748190
21acrosome assembly (GO:0001675)4.67002322
22multicellular organism reproduction (GO:0032504)4.61992875
23regulation of relaxation of muscle (GO:1901077)4.53710155
24nuclear pore organization (GO:0006999)4.48446141
25synaptonemal complex organization (GO:0070193)4.39183413
26piRNA metabolic process (GO:0034587)4.39122608
27synaptonemal complex assembly (GO:0007130)4.37663396
28motile cilium assembly (GO:0044458)4.32283009
29cardiac myofibril assembly (GO:0055003)4.29118336
30plasma membrane fusion (GO:0045026)4.24456980
31negative regulation of potassium ion transmembrane transporter activity (GO:1901017)4.21166604
32male meiosis (GO:0007140)4.13769232
33cardiac muscle contraction (GO:0060048)4.13111101
34positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.10290315
35response to muscle activity (GO:0014850)4.09132330
36spermatid development (GO:0007286)4.07583253
37mitotic sister chromatid cohesion (GO:0007064)4.02828744
38axonemal dynein complex assembly (GO:0070286)3.99095114
39protein localization to chromosome, centromeric region (GO:0071459)3.96477804
40heterochromatin organization (GO:0070828)3.95710900
41skeletal muscle fiber development (GO:0048741)3.92200818
42actomyosin structure organization (GO:0031032)3.90942863
43plasma membrane repair (GO:0001778)3.88241437
44skeletal muscle tissue regeneration (GO:0043403)3.87629512
45response to inactivity (GO:0014854)3.86713391
46positive regulation of myotube differentiation (GO:0010831)3.85584910
47reproduction (GO:0000003)3.84479793
48striated muscle atrophy (GO:0014891)3.76128109
49negative regulation of potassium ion transmembrane transport (GO:1901380)3.72112408
50muscle contraction (GO:0006936)3.70000885
51mitotic nuclear envelope disassembly (GO:0007077)3.64326403
52acrosome reaction (GO:0007340)3.63705578
53pore complex assembly (GO:0046931)3.61169997
54DNA replication-dependent nucleosome organization (GO:0034723)3.60917809
55DNA replication-dependent nucleosome assembly (GO:0006335)3.60917809
56glycogen catabolic process (GO:0005980)3.60111466
57protein localization to kinetochore (GO:0034501)3.58094356
58gene silencing by RNA (GO:0031047)3.53664549
59striated muscle adaptation (GO:0014888)3.52251720
60cardiac muscle hypertrophy (GO:0003300)3.46292832
61regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.46137380
62chromosome condensation (GO:0030261)3.44941590
63nuclear envelope disassembly (GO:0051081)3.44558516
64membrane disassembly (GO:0030397)3.44558516
65epithelial cilium movement (GO:0003351)3.44219037
66chaperone-mediated protein complex assembly (GO:0051131)3.44101063
67glycogen biosynthetic process (GO:0005978)3.43355272
68glucan biosynthetic process (GO:0009250)3.43355272
69microtubule depolymerization (GO:0007019)3.42424527
70glucan catabolic process (GO:0009251)3.42393283
71monoubiquitinated protein deubiquitination (GO:0035520)3.40976461
72negative regulation of erythrocyte differentiation (GO:0045647)3.40369929
73regulation of histone H3-K9 methylation (GO:0051570)3.37655361
74muscle tissue morphogenesis (GO:0060415)3.36746670
75cell-substrate adherens junction assembly (GO:0007045)3.35720183
76focal adhesion assembly (GO:0048041)3.35720183
77muscle system process (GO:0003012)3.34615378
78cardiac muscle tissue morphogenesis (GO:0055008)3.32711522
79myotube cell development (GO:0014904)3.32378585
80muscle atrophy (GO:0014889)3.30145187
81striated muscle hypertrophy (GO:0014897)3.27319230
82cellular polysaccharide catabolic process (GO:0044247)3.27222669
83interferon-gamma secretion (GO:0072643)3.26322532
84regulation of actin filament-based movement (GO:1903115)3.26160310
85chromosome organization involved in meiosis (GO:0070192)3.24149202
86NADH metabolic process (GO:0006734)3.21441281
87muscle cell fate commitment (GO:0042693)3.21368404
88mitotic sister chromatid segregation (GO:0000070)3.20956571
89IMP metabolic process (GO:0046040)3.18601003
90regulation of translational fidelity (GO:0006450)3.17762366
91DNA packaging (GO:0006323)3.16351997
92skeletal muscle tissue development (GO:0007519)3.15624802
93DNA unwinding involved in DNA replication (GO:0006268)3.15174542
94chromatin assembly (GO:0031497)3.14730782
95meiotic nuclear division (GO:0007126)3.10813000
96IMP biosynthetic process (GO:0006188)3.10309458
97muscle hypertrophy (GO:0014896)3.09701618
98muscle adaptation (GO:0043500)3.08823872
99sister chromatid segregation (GO:0000819)3.07681972
100regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.00444263
101regulation of myotube differentiation (GO:0010830)2.99129714
102regulation of RNA export from nucleus (GO:0046831)2.97616010
103formation of translation preinitiation complex (GO:0001731)2.97586258
104positive regulation of chromosome segregation (GO:0051984)2.97479651
105regulation of centriole replication (GO:0046599)2.97385437
106positive regulation of mitotic sister chromatid separation (GO:1901970)2.96898392
107positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.96898392
108positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.96898392
109cell-substrate junction assembly (GO:0007044)2.96849020
110gene silencing (GO:0016458)2.96527563
111single fertilization (GO:0007338)2.95392799
112adherens junction assembly (GO:0034333)2.94732582
113mitotic chromosome condensation (GO:0007076)2.93245996
114male meiosis I (GO:0007141)2.93032797
115epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.90809474
116pinocytosis (GO:0006907)2.88724592
117viral transcription (GO:0019083)2.88561014
118nuclear envelope organization (GO:0006998)2.87665686
119polysaccharide catabolic process (GO:0000272)2.87002866
120glycogen metabolic process (GO:0005977)2.86479002
121translational termination (GO:0006415)2.86076578
122regulation of cilium movement (GO:0003352)2.85885783
123muscle filament sliding (GO:0030049)2.83150870
124actin-myosin filament sliding (GO:0033275)2.83150870
125cellular glucan metabolic process (GO:0006073)2.82095452
126glucan metabolic process (GO:0044042)2.82095452
127regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.80164362
128negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.80072625
129muscle organ morphogenesis (GO:0048644)2.78237860
130negative regulation of myotube differentiation (GO:0010832)2.76954423
131translational initiation (GO:0006413)2.75871331
132* mRNA stabilization (GO:0048255)2.74349273
133* RNA stabilization (GO:0043489)2.74349273
134maturation of SSU-rRNA (GO:0030490)2.73095748
135translesion synthesis (GO:0019985)2.71754859
136meiotic cell cycle (GO:0051321)2.69649088
137cilium movement (GO:0003341)2.68791001
138folic acid-containing compound biosynthetic process (GO:0009396)2.68558233
139cardiac muscle adaptation (GO:0014887)2.68467429
140cardiac muscle hypertrophy in response to stress (GO:0014898)2.68467429
141muscle hypertrophy in response to stress (GO:0003299)2.68467429
142DNA replication initiation (GO:0006270)2.68438433
143translational elongation (GO:0006414)2.68416678
144regulation of myoblast differentiation (GO:0045661)2.68160253
145carnitine shuttle (GO:0006853)2.67058774
146nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.66978333
147* spermatogenesis (GO:0007283)2.66127376
148* male gamete generation (GO:0048232)2.65749231
149protein localization to chromosome (GO:0034502)2.65160616
150meiosis I (GO:0007127)2.65011274
151regulation of translational termination (GO:0006449)2.63779738
152lymph vessel development (GO:0001945)2.63376624
153regulation of centrosome cycle (GO:0046605)2.62844662
154regulation of posttranscriptional gene silencing (GO:0060147)2.62744091
155regulation of gene silencing by miRNA (GO:0060964)2.62744091
156regulation of gene silencing by RNA (GO:0060966)2.62744091
157negative regulation of DNA repair (GO:0045738)2.61770057
158cellular response to epinephrine stimulus (GO:0071872)2.61149787
159muscle fiber development (GO:0048747)2.61053918
160oxygen transport (GO:0015671)2.60891280
161definitive hemopoiesis (GO:0060216)2.59818934
162protoporphyrinogen IX metabolic process (GO:0046501)2.59507391
163NLS-bearing protein import into nucleus (GO:0006607)2.59011609
164* fertilization (GO:0009566)2.58638212
165regulation of spindle checkpoint (GO:0090231)2.58516845
1662-oxoglutarate metabolic process (GO:0006103)2.58217671
167mitotic metaphase plate congression (GO:0007080)2.57829864
168heart process (GO:0003015)2.57294992
169heart contraction (GO:0060047)2.57294992
170desmosome organization (GO:0002934)2.56981420
171DNA conformation change (GO:0071103)2.56189431
172sperm capacitation (GO:0048240)2.56155580
173ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.55878615
174peptidyl-lysine dimethylation (GO:0018027)2.55614933
175DNA methylation involved in gamete generation (GO:0043046)2.55332621
176regulation of chromosome segregation (GO:0051983)2.54467348
1773-UTR-mediated mRNA stabilization (GO:0070935)2.53867905
178* regulation of necroptotic process (GO:0060544)2.51487486
179negative regulation of cell size (GO:0045792)2.50491784
180negative regulation of striated muscle cell differentiation (GO:0051154)2.49030264
181muscle organ development (GO:0007517)2.48146019
182hemoglobin metabolic process (GO:0020027)2.46392564
183negative regulation of muscle cell differentiation (GO:0051148)2.45321597
184muscle structure development (GO:0061061)2.44739029
185regulation of striated muscle contraction (GO:0006942)2.44494758
186* negative regulation of necroptotic process (GO:0060546)2.42733422
187positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.42418023
188positive regulation of receptor recycling (GO:0001921)2.42051256
189negative regulation of myoblast differentiation (GO:0045662)2.41956033
190carnitine transmembrane transport (GO:1902603)2.39392498
191adult heart development (GO:0007512)2.37224121
192cardiac muscle cell development (GO:0055013)2.36738222
193regulation of the force of heart contraction (GO:0002026)2.36388910
194response to epinephrine (GO:0071871)2.35877712
195embryonic process involved in female pregnancy (GO:0060136)2.33944625
196regulation of skeletal muscle fiber development (GO:0048742)2.33426676
197muscle cell cellular homeostasis (GO:0046716)2.33346333

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.92599001
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.95724432
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.78416154
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.03534276
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.39685367
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.09639495
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.08362433
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.03270864
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.97785385
10RARG_19884340_ChIP-ChIP_MEFs_Mouse2.49407081
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.38622531
12KDM2B_26808549_Chip-Seq_SUP-B15_Human2.17688260
13AR_21909140_ChIP-Seq_LNCAP_Human2.13903642
14PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.13359806
15TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.06220481
16MYC_22102868_ChIP-Seq_BL_Human2.05838283
17ZNF263_19887448_ChIP-Seq_K562_Human1.98673916
18STAT6_21828071_ChIP-Seq_BEAS2B_Human1.96490827
19MYC_19030024_ChIP-ChIP_MESCs_Mouse1.94628060
20EGR1_19374776_ChIP-ChIP_THP-1_Human1.81844447
21TBX20_22328084_ChIP-Seq_HEART_Mouse1.79912173
22TBX20_22080862_ChIP-Seq_HEART_Mouse1.79912173
23MYC_18358816_ChIP-ChIP_MESCs_Mouse1.78833312
24SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.77230033
25CLOCK_20551151_ChIP-Seq_293T_Human1.76079331
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.76003506
27CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.75248788
28VDR_24763502_ChIP-Seq_THP-1_Human1.73634395
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.71592523
30LXR_22292898_ChIP-Seq_THP-1_Human1.70512532
31STAT3_1855785_ChIP-Seq_MESCs_Mouse1.68698102
32XRN2_22483619_ChIP-Seq_HELA_Human1.65036584
33NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.62971419
34SCL_19346495_ChIP-Seq_HPC-7_Human1.58534136
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57381083
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.53712593
37NELFA_20434984_ChIP-Seq_ESCs_Mouse1.51478150
38DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.48113363
39ESR2_21235772_ChIP-Seq_MCF-7_Human1.47954047
40KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.47707880
41GATA1_19941827_ChIP-Seq_MEL_Mouse1.45990560
42KLF4_18555785_ChIP-Seq_MESCs_Mouse1.45571549
43GATA1_19941826_ChIP-Seq_K562_Human1.45418176
44GATA1_22025678_ChIP-Seq_K562_Human1.41683864
45TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.40838732
46NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39383359
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.38430372
48RUNX1_22412390_ChIP-Seq_EML_Mouse1.38226557
49CTCF_27219007_Chip-Seq_ERYTHROID_Human1.37390132
50GATA1_22383799_ChIP-Seq_G1ME_Mouse1.37320069
51TCF7_22412390_ChIP-Seq_EML_Mouse1.35546605
52HIF1A_21447827_ChIP-Seq_MCF-7_Human1.35317410
53TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.34522091
54ATF3_27146783_Chip-Seq_COLON_Human1.32996690
55MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.32893146
56CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.29687769
57KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.29596083
58KDM2B_26808549_Chip-Seq_JURKAT_Human1.29519364
59CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.27446719
60KDM2B_26808549_Chip-Seq_K562_Human1.25841428
61KDM5A_27292631_Chip-Seq_BREAST_Human1.25454506
62VDR_21846776_ChIP-Seq_THP-1_Human1.24126636
63ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.23892317
64GATA2_22383799_ChIP-Seq_G1ME_Mouse1.23558601
65ETS1_20019798_ChIP-Seq_JURKAT_Human1.22642700
66SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.21561290
67CREB1_15753290_ChIP-ChIP_HEK293T_Human1.19926544
68TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.19758910
69ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.19561963
70ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18200013
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.17980535
72CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.17195406
73HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16564665
74ZFX_18555785_ChIP-Seq_MESCs_Mouse1.15744415
75TTF2_22483619_ChIP-Seq_HELA_Human1.15555734
76NANOG_18555785_ChIP-Seq_MESCs_Mouse1.12510910
77P63_26484246_Chip-Seq_KERATINOCYTES_Human1.12433688
78E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.12194221
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11843546
80SA1_27219007_Chip-Seq_ERYTHROID_Human1.11169745
81RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10994923
82DCP1A_22483619_ChIP-Seq_HELA_Human1.10462250
83POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.10150436
84CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.09906696
85ESR1_20079471_ChIP-ChIP_T-47D_Human1.09311014
86KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.09234682
87GATA4_21415370_ChIP-Seq_HL-1_Mouse1.07675013
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07104372
89CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05541253
90KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.05133210
91PPARA_22158963_ChIP-Seq_LIVER_Mouse1.04481530
92TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.04330811
93NFIB_24661679_ChIP-Seq_LUNG_Mouse1.03764401
94SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03398356
95NCOR1_26117541_ChIP-Seq_K562_Human1.02509832
96STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.02404778
97EST1_17652178_ChIP-ChIP_JURKAT_Human1.02358533
98SPI1_23127762_ChIP-Seq_K562_Human1.02343708
99FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.01782397
100VDR_23849224_ChIP-Seq_CD4+_Human1.01632577
101PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.01602311
102CREB1_26743006_Chip-Seq_LNCaP_Human1.00469422
103CTCF_21964334_Chip-Seq_Bcells_Human1.00275117
104GATA2_19941826_ChIP-Seq_K562_Human1.00046332
105BRD4_27068464_Chip-Seq_AML-cells_Mouse0.99645300
106ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.99272521
107TP53_22127205_ChIP-Seq_IMR90_Human0.97992260
108RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.97893043
109YY1_22570637_ChIP-Seq_MALME-3M_Human0.97355199
110UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.97332042
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.97315440
112ELK3_25401928_ChIP-Seq_HUVEC_Human0.97197331
113KDM2B_26808549_Chip-Seq_DND41_Human0.96420612
114IRF8_22096565_ChIP-ChIP_GC-B_Human0.96072370
115CHD1_26751641_Chip-Seq_LNCaP_Human0.96013734
116GABP_19822575_ChIP-Seq_HepG2_Human0.95169569
117ELF1_20517297_ChIP-Seq_JURKAT_Human0.94771488
118PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94251805
119UTX_26944678_Chip-Seq_JUKART_Human0.93382591
120WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.92659572
121ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.91820366
122NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.91805178
123FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.91700738
124CTCF_21964334_ChIP-Seq_BJAB-B_Human0.90922495
125KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.90538127
126MAF_26560356_Chip-Seq_TH1_Human0.90152929
127UBF1/2_26484160_Chip-Seq_HMECs_Human0.88484005
128E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87720217
129TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.87517913
130FOXP3_21729870_ChIP-Seq_TREG_Human0.86590961
131TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.86441868
132MYB_21317192_ChIP-Seq_ERMYB_Mouse0.86214077
133GATA6_25053715_ChIP-Seq_YYC3_Human0.84554354
134BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.84263488
135TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83905688
136NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.83417539
137RBPJ_22232070_ChIP-Seq_NCS_Mouse0.83199299
138CIITA_25753668_ChIP-Seq_RAJI_Human0.83100527
139TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.82902503
140P68_20966046_ChIP-Seq_HELA_Human0.81364059
141PHF8_20622854_ChIP-Seq_HELA_Human0.80734749
142CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80259319
143MAF_26560356_Chip-Seq_TH2_Human0.80031836
144SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.79615710
145SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.79615710
146E2F1_18555785_ChIP-Seq_MESCs_Mouse0.75424731
147SOX2_18555785_ChIP-Seq_MESCs_Mouse0.75370668
148TFEB_21752829_ChIP-Seq_HELA_Human0.74919636
149SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.74669696
150MYB_26560356_Chip-Seq_TH1_Human0.73846300
151RACK7_27058665_Chip-Seq_MCF-7_Human0.72815231
152FOXP1_21924763_ChIP-Seq_HESCs_Human0.72587366
153P300_27058665_Chip-Seq_ZR-75-30cells_Human0.71667228

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization4.48816884
2MP0005451_abnormal_body_composition3.93680098
3MP0003705_abnormal_hypodermis_morpholog2.95794766
4MP0010352_gastrointestinal_tract_polyps2.68919548
5MP0003111_abnormal_nucleus_morphology2.61594406
6MP0010094_abnormal_chromosome_stability2.47716022
7MP0002332_abnormal_exercise_endurance2.45907284
8MP0003693_abnormal_embryo_hatching2.44421276
9MP0004957_abnormal_blastocyst_morpholog2.40585452
10MP0002796_impaired_skin_barrier2.23448272
11MP0005275_abnormal_skin_tensile2.21268496
12MP0003828_pulmonary_edema2.11249248
13MP0003077_abnormal_cell_cycle2.08191924
14MP0004130_abnormal_muscle_cell2.06042034
15MP0005076_abnormal_cell_differentiation1.99478640
16MP0003646_muscle_fatigue1.97129206
17MP0001929_abnormal_gametogenesis1.93259189
18MP0008057_abnormal_DNA_replication1.92541954
19MP0008877_abnormal_DNA_methylation1.90175881
20MP0005620_abnormal_muscle_contractility1.88430707
21MP0000733_abnormal_muscle_development1.85509504
22MP0005501_abnormal_skin_physiology1.82295466
23MP0004510_myositis1.78540979
24MP0003656_abnormal_erythrocyte_physiolo1.77646691
25MP0003698_abnormal_male_reproductive1.77297580
26MP0001730_embryonic_growth_arrest1.73746060
27MP0006138_congestive_heart_failure1.72615839
28MP0010307_abnormal_tumor_latency1.72073789
29MP0000750_abnormal_muscle_regeneration1.71261218
30MP0002972_abnormal_cardiac_muscle1.69550755
31MP0000749_muscle_degeneration1.65073780
32MP0003950_abnormal_plasma_membrane1.64732311
33MP0004185_abnormal_adipocyte_glucose1.63477875
34MP0004233_abnormal_muscle_weight1.62388911
35MP0005623_abnormal_meninges_morphology1.61115287
36MP0008007_abnormal_cellular_replicative1.59195033
37MP0003566_abnormal_cell_adhesion1.59182761
38MP0010234_abnormal_vibrissa_follicle1.56519330
39MP0003221_abnormal_cardiomyocyte_apopto1.54867932
40MP0002653_abnormal_ependyma_morphology1.50374441
41MP0002210_abnormal_sex_determination1.50245497
42MP0003941_abnormal_skin_development1.48285462
43MP0004145_abnormal_muscle_electrophysio1.47761763
44MP0004197_abnormal_fetal_growth/weight/1.47633221
45MP0000350_abnormal_cell_proliferation1.46712204
46MP0002108_abnormal_muscle_morphology1.45236303
47MP0008260_abnormal_autophagy1.44900554
48MP0004087_abnormal_muscle_fiber1.42449011
49MP0004484_altered_response_of1.40862519
50MP0002060_abnormal_skin_morphology1.36499266
51MP0010030_abnormal_orbit_morphology1.35247275
52MP0005380_embryogenesis_phenotype1.31284663
53MP0001672_abnormal_embryogenesis/_devel1.31284663
54MP0001697_abnormal_embryo_size1.30280612
55MP0002269_muscular_atrophy1.29436183
56MP0002106_abnormal_muscle_physiology1.29148912
57MP0006036_abnormal_mitochondrial_physio1.28946650
58MP0002877_abnormal_melanocyte_morpholog1.28501473
59MP0002084_abnormal_developmental_patter1.27954298
60MP0001145_abnormal_male_reproductive1.27364941
61MP0008058_abnormal_DNA_repair1.27293195
62MP0000759_abnormal_skeletal_muscle1.27149821
63MP0000751_myopathy1.26181949
64MP0003984_embryonic_growth_retardation1.24871791
65MP0002088_abnormal_embryonic_growth/wei1.22800207
66MP0008932_abnormal_embryonic_tissue1.21703905
67MP0005397_hematopoietic_system_phenotyp1.21684136
68MP0001545_abnormal_hematopoietic_system1.21684136
69MP0002127_abnormal_cardiovascular_syste1.20248375
70MP0000003_abnormal_adipose_tissue1.19976485
71MP0003303_peritoneal_inflammation1.19758070
72MP0002086_abnormal_extraembryonic_tissu1.18909800
73MP0001216_abnormal_epidermal_layer1.17761480
74MP0005385_cardiovascular_system_phenoty1.17332797
75MP0001544_abnormal_cardiovascular_syste1.17332797
76MP0002085_abnormal_embryonic_tissue1.16945122
77MP0000013_abnormal_adipose_tissue1.16693391
78MP0009278_abnormal_bone_marrow1.16463699
79MP0000747_muscle_weakness1.15959414
80MP0004808_abnormal_hematopoietic_stem1.15604584
81MP0001661_extended_life_span1.13227604
82MP0002080_prenatal_lethality1.12271783
83MP0005666_abnormal_adipose_tissue1.11147676
84MP0003453_abnormal_keratinocyte_physiol1.11109136
85MP0008438_abnormal_cutaneous_collagen1.08996853
86MP0005023_abnormal_wound_healing1.08942679
87MP0004215_abnormal_myocardial_fiber1.07905520
88MP0001849_ear_inflammation1.06758753
89MP0000653_abnormal_sex_gland1.05929138
90MP0005266_abnormal_metabolism1.04741774
91MP0002396_abnormal_hematopoietic_system1.04564246
92MP0000537_abnormal_urethra_morphology1.03349023
93MP0010630_abnormal_cardiac_muscle1.03063775
94MP0000383_abnormal_hair_follicle1.02686746
95MP0000377_abnormal_hair_follicle1.02479706
96MP0003567_abnormal_fetal_cardiomyocyte1.02061047
97MP0005369_muscle_phenotype1.01471224
98MP0002161_abnormal_fertility/fecundity1.00896257
99MP0002971_abnormal_brown_adipose1.00252193
100MP0002837_dystrophic_cardiac_calcinosis0.99172287
101MP0004084_abnormal_cardiac_muscle0.98608630
102MP0003786_premature_aging0.97520424
103MP0004858_abnormal_nervous_system0.95987353
104MP0006054_spinal_hemorrhage0.95398351
105MP0010678_abnormal_skin_adnexa0.93691348
106MP0009931_abnormal_skin_appearance0.91775081
107MP0009053_abnormal_anal_canal0.90719176
108MP0004036_abnormal_muscle_relaxation0.90648486
109MP0000490_abnormal_crypts_of0.89984389
110MP0002282_abnormal_trachea_morphology0.88019378
111MP0002234_abnormal_pharynx_morphology0.87584324
112MP0000313_abnormal_cell_death0.86569204
113MP0003763_abnormal_thymus_physiology0.85553416
114MP0002019_abnormal_tumor_incidence0.85205104
115MP0009672_abnormal_birth_weight0.84954793
116MP0010771_integument_phenotype0.82962497
117MP0000647_abnormal_sebaceous_gland0.82426241
118MP0005375_adipose_tissue_phenotype0.82038053
119MP0003091_abnormal_cell_migration0.81278233
120MP0010368_abnormal_lymphatic_system0.80626832
121MP0001293_anophthalmia0.79950058
122MP0004947_skin_inflammation0.79843659
123MP0002132_abnormal_respiratory_system0.79805487
124MP0000266_abnormal_heart_morphology0.76669006
125MP0001243_abnormal_dermal_layer0.76596563
126MP0003191_abnormal_cellular_cholesterol0.76468153
127MP0005670_abnormal_white_adipose0.76299616
128MP0005083_abnormal_biliary_tract0.76018892
129MP0003045_fibrosis0.75908226
130MP0003123_paternal_imprinting0.75540649
131MP0001915_intracranial_hemorrhage0.75334090
132MP0000678_abnormal_parathyroid_gland0.75326008
133MP0005330_cardiomyopathy0.75056992
134MP0000762_abnormal_tongue_morphology0.74988237
135MP0002925_abnormal_cardiovascular_devel0.74695796
136MP0000579_abnormal_nail_morphology0.74207655
137MP0003436_decreased_susceptibility_to0.73152039
138MP0003279_aneurysm0.69232667
139MP0002128_abnormal_blood_circulation0.67572993
140MP0000858_altered_metastatic_potential0.67432799
141MP0003300_gastrointestinal_ulcer0.66970211
142MP0000767_abnormal_smooth_muscle0.66121374
143MP0004272_abnormal_basement_membrane0.65790918
144MP0005464_abnormal_platelet_physiology0.64834801
145MP0005165_increased_susceptibility_to0.64737906
146MP0001851_eye_inflammation0.64428773
147MP0002009_preneoplasia0.61936553
148MP0008775_abnormal_heart_ventricle0.59419139
149MP0009333_abnormal_splenocyte_physiolog0.55335458
150MP0001784_abnormal_fluid_regulation0.54682693
151MP0000685_abnormal_immune_system0.54152404

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.68640720
2Centrally nucleated skeletal muscle fibers (HP:0003687)4.77081601
3Absent/shortened dynein arms (HP:0200106)4.70712413
4Dynein arm defect of respiratory motile cilia (HP:0012255)4.70712413
5Muscle fiber inclusion bodies (HP:0100299)4.61876317
6Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.53369035
7Exercise-induced muscle cramps (HP:0003710)4.05962300
8Type 1 muscle fiber predominance (HP:0003803)4.05495934
9Nemaline bodies (HP:0003798)4.05114010
10Ulnar deviation of the wrist (HP:0003049)3.77307159
11Hyporeflexia of lower limbs (HP:0002600)3.71095696
12Increased connective tissue (HP:0009025)3.66976415
13Nasal polyposis (HP:0100582)3.60630105
14Difficulty climbing stairs (HP:0003551)3.50496952
15Round ear (HP:0100830)3.32579171
16Distal arthrogryposis (HP:0005684)3.31697490
17Exercise-induced myalgia (HP:0003738)3.30540237
18Sudden death (HP:0001699)3.30446305
19Difficulty running (HP:0009046)3.27154131
20Asymmetric septal hypertrophy (HP:0001670)3.26112117
21Calcaneovalgus deformity (HP:0001848)3.25134755
22Abnormal respiratory motile cilium physiology (HP:0012261)3.21160304
23Muscle fiber splitting (HP:0003555)3.20423074
24Chronic bronchitis (HP:0004469)3.14768035
25Rimmed vacuoles (HP:0003805)3.11061751
26Progressive muscle weakness (HP:0003323)3.08995462
27Myopathic facies (HP:0002058)3.03179403
28Abnormal respiratory motile cilium morphology (HP:0005938)3.01177196
29Abnormal respiratory epithelium morphology (HP:0012253)3.01177196
30Deformed tarsal bones (HP:0008119)2.96901621
31Selective tooth agenesis (HP:0001592)2.93220598
32Abnormality of the nasal mucosa (HP:0000433)2.91973711
33Rhinitis (HP:0012384)2.88073388
34Abnormality of the calcaneus (HP:0008364)2.76794654
35Bulbar palsy (HP:0001283)2.71900236
36Rhabdomyolysis (HP:0003201)2.60123423
37Bundle branch block (HP:0011710)2.56073294
38Dilated cardiomyopathy (HP:0001644)2.56025219
39Lipoatrophy (HP:0100578)2.47101193
40Infertility (HP:0000789)2.46617016
41Myoglobinuria (HP:0002913)2.44587592
42Abnormality of cells of the erythroid lineage (HP:0012130)2.41708610
43Scapular winging (HP:0003691)2.38607557
44Ragged-red muscle fibers (HP:0003200)2.37365644
45Trismus (HP:0000211)2.31114639
46Lower limb amyotrophy (HP:0007210)2.29309280
47Abnormal number of erythroid precursors (HP:0012131)2.29076250
48Spinal rigidity (HP:0003306)2.27518804
49Abnormality of the foot musculature (HP:0001436)2.26780953
50Increased density of long bones (HP:0006392)2.25756220
51Areflexia of lower limbs (HP:0002522)2.25545336
52Pelvic girdle muscle weakness (HP:0003749)2.25480635
53Foot dorsiflexor weakness (HP:0009027)2.23561466
54Male infertility (HP:0003251)2.22119563
55Abnormal finger flexion creases (HP:0006143)2.18308655
56Right ventricular cardiomyopathy (HP:0011663)2.16941976
57Protrusio acetabuli (HP:0003179)2.16110738
58Myotonia (HP:0002486)2.12110208
59Hyperkalemia (HP:0002153)2.08206239
60Limb-girdle muscle atrophy (HP:0003797)2.07472363
61Absent phalangeal crease (HP:0006109)2.07339652
62Muscle hypertrophy of the lower extremities (HP:0008968)2.07218760
63Slender build (HP:0001533)2.01923563
64Abnormality of the left ventricular outflow tract (HP:0011103)2.01268992
65Subaortic stenosis (HP:0001682)2.01268992
66Malignant hyperthermia (HP:0002047)2.00931700
67Weak cry (HP:0001612)2.00704387
68Impulsivity (HP:0100710)1.98926925
69Milia (HP:0001056)1.98326243
70Abnormal ciliary motility (HP:0012262)1.98076498
71Abnormality of the neuromuscular junction (HP:0003398)1.97856282
72Fatigable weakness (HP:0003473)1.97856282
73Bronchitis (HP:0012387)1.97402899
74Abnormality of skeletal muscle fiber size (HP:0012084)1.96282258
75Calf muscle hypertrophy (HP:0008981)1.95173474
76Abnormality of the musculature of the pelvis (HP:0001469)1.94804988
77Abnormality of the hip-girdle musculature (HP:0001445)1.94804988
78Pili torti (HP:0003777)1.94418570
79Ventricular tachycardia (HP:0004756)1.93410468
80Dysmetric saccades (HP:0000641)1.92382960
81Rectal prolapse (HP:0002035)1.92172663
82EMG: neuropathic changes (HP:0003445)1.92076350
83Gowers sign (HP:0003391)1.90921410
84Shoulder girdle muscle weakness (HP:0003547)1.88031620
85Mildly elevated creatine phosphokinase (HP:0008180)1.85540314
86Premature rupture of membranes (HP:0001788)1.85517711
87Reticulocytosis (HP:0001923)1.85243022
88Waddling gait (HP:0002515)1.82621600
89Abnormality of reticulocytes (HP:0004312)1.82172264
90Muscular dystrophy (HP:0003560)1.81815845
91Distal lower limb muscle weakness (HP:0009053)1.81520526
92Fatigue (HP:0012378)1.81315748
93High pitched voice (HP:0001620)1.80358708
94Short palpebral fissure (HP:0012745)1.79393398
95Achilles tendon contracture (HP:0001771)1.78657260
96Abnormality of the anterior horn cell (HP:0006802)1.78510654
97Degeneration of anterior horn cells (HP:0002398)1.78510654
98EMG: myopathic abnormalities (HP:0003458)1.78406592
99Neck muscle weakness (HP:0000467)1.77542938
100Reticulocytopenia (HP:0001896)1.76713139
101Popliteal pterygium (HP:0009756)1.76593462
102Ankle contracture (HP:0006466)1.76335644
103Hip contracture (HP:0003273)1.76051564
104Limb-girdle muscle weakness (HP:0003325)1.75353066
105Paralysis (HP:0003470)1.73042860
106Muscle stiffness (HP:0003552)1.71221842
107Woolly hair (HP:0002224)1.69300077
108Abnormality of nail color (HP:0100643)1.69059369
109Increased variability in muscle fiber diameter (HP:0003557)1.68659093
110Missing ribs (HP:0000921)1.68523740
111Abnormal atrioventricular conduction (HP:0005150)1.68468230
112Biliary tract neoplasm (HP:0100574)1.68426812
113Proximal amyotrophy (HP:0007126)1.67542974
114Frequent falls (HP:0002359)1.64930649
115Bronchiectasis (HP:0002110)1.63521955
116Distal lower limb amyotrophy (HP:0008944)1.62070177
117Abnormality of the shoulder girdle musculature (HP:0001435)1.61753243
118Ventricular arrhythmia (HP:0004308)1.61427852
119Abnormality of the calf musculature (HP:0001430)1.61276340
120Ependymoma (HP:0002888)1.60651390
121Heart block (HP:0012722)1.60472444
122Abnormality of the Achilles tendon (HP:0005109)1.59482711
123Generalized amyotrophy (HP:0003700)1.58377216
124Deviation of the thumb (HP:0009603)1.58080422
125Heterotopia (HP:0002282)1.57882944
126Short humerus (HP:0005792)1.57363796
127Metatarsus adductus (HP:0001840)1.55522298
128Progressive external ophthalmoplegia (HP:0000590)1.55343361
129Generalized muscle weakness (HP:0003324)1.54911472
130Easy fatigability (HP:0003388)1.54053480
131Polycythemia (HP:0001901)1.53851116
13211 pairs of ribs (HP:0000878)1.53139313
133Abnormal spermatogenesis (HP:0008669)1.53097435
134Aplasia/hypoplasia of the humerus (HP:0006507)1.52772663
135Squamous cell carcinoma (HP:0002860)1.52066994
136Proximal placement of thumb (HP:0009623)1.51386342
137Increased IgE level (HP:0003212)1.50755955
138Hypochromic microcytic anemia (HP:0004840)1.50407378
139Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.50289743
140Abnormality of the salivary glands (HP:0010286)1.45418532
141Diaphragmatic weakness (HP:0009113)1.44194824
142Atrioventricular block (HP:0001678)1.40727615
143Reduced subcutaneous adipose tissue (HP:0003758)1.40120005
144Fetal akinesia sequence (HP:0001989)1.38963099
145Palmoplantar keratoderma (HP:0000982)1.38875253
146Aortic aneurysm (HP:0004942)1.37645661

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK44.73078624
2PDK34.73078624
3EEF2K3.05252555
4PDK22.88180059
5TTN2.77671149
6NEK22.73517627
7TRIB32.70361513
8TESK12.62633989
9CDC72.58655579
10CDK122.41438842
11ICK2.28147370
12PRPF4B2.25654636
13SMG12.15752961
14PKN22.09159133
15WEE11.94925199
16TTK1.85231629
17TAOK21.77987329
18MAP3K101.76256536
19MAP3K71.75011848
20MAP3K131.69438079
21OBSCN1.68245626
22PRKD31.67850152
23RPS6KB21.61780311
24NEK11.58665761
25STK31.57884279
26MAPK121.53101385
27LATS11.52150642
28EPHA21.51444792
29STK101.49085082
30MAPKAPK31.34901234
31RPS6KA41.28541525
32BUB11.23586319
33IRAK31.21434832
34DYRK31.20937446
35NME21.17178477
36MAP3K81.16224528
37CDK41.15089811
38MAP2K31.14355480
39CDK61.12886077
40MAP3K11.11872303
41LRRK21.08627474
42MTOR1.07288148
43AURKB1.03923087
44CHEK21.02807604
45MOS1.01362188
46PAK41.00816133
47CHEK11.00128934
48PNCK0.97415482
49BMX0.95741248
50SIK10.95277088
51MAP3K30.95062522
52ATR0.94327371
53TBK10.94251365
54CDK70.94088291
55KSR20.92316290
56PLK10.92293346
57PASK0.92227662
58DMPK0.91547434
59PAK20.89200292
60BRSK20.89001516
61MARK20.86650750
62PRKAA20.85652910
63CDC42BPA0.85511289
64MUSK0.84880703
65STK40.84671369
66DYRK1B0.83347243
67EIF2AK10.82961199
68PTK60.79919550
69EPHB10.74782445
70ILK0.74748021
71GRK60.74018414
72PTK2B0.73830874
73ATM0.73586162
74IRAK40.73032379
75RPS6KL10.72722521
76RPS6KC10.72722521
77PIM20.72182082
78TAOK10.71546259
79PIM10.71269478
80TRPM70.70591054
81MAP3K140.69904047
82MAPK110.69790292
83SCYL20.66272056
84MAP3K60.65968334
85SGK30.64391599
86MAPK70.63469710
87PIK3CG0.63152114
88TGFBR20.61871815
89TESK20.61540795
90ALK0.61323995
91AURKA0.61034537
92LATS20.59312495
93PAK10.58540115
94RPS6KA60.58020060
95RIPK10.57732598
96PDPK10.57686560
97CDK20.56745463
98ZAP700.56606594
99KDR0.56422842
100AKT20.56293692
101STK38L0.56138981
102CSK0.53988139
103TLK10.53350543
104ZAK0.52562986
105NME10.51849399
106JAK30.51436842
107MET0.50294514
108MAP3K110.49975826
109HIPK20.49572552
110PLK40.49305961
111SRPK10.49226591
112MAP4K10.49054732
113PRKD20.46208401
114TIE10.45592337
115RPS6KA10.44684368
116IRAK20.44172272
117RIPK40.43235653
118MAP3K50.43127323
119MELK0.42659720
120MAPK40.42579091
121PDGFRA0.42295730
122FGFR10.41775870
123MST1R0.41615181
124ARAF0.40620466
125ERN10.40565926
126CSNK1D0.39206923
127BRD40.38887345
128DDR20.38814225
129TSSK60.38752751
130TGFBR10.37775112
131STK240.37496605
132CDK10.37300065
133MAP2K20.37266670
134FLT30.36851718
135BLK0.36728656
136RAF10.36397180
137MAPKAPK20.35992198
138CAMK40.35231890
139HCK0.35168394
140MAP2K10.35029553
141MAP2K40.34249800
142RPS6KA50.33174175
143FGR0.33092123
144RPS6KA20.33036486
145CSNK2A20.32171444
146TYRO30.31996888
147BRAF0.31745462
148FGFR40.31740706
149PLK30.31632976
150PHKG10.30455651
151PHKG20.30455651
152NEK90.29456205
153CDK90.29036650
154CSNK1E0.28365169
155PRKDC0.28185106

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.07281505
2RNA transport_Homo sapiens_hsa030133.03569358
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.48572881
4Cell cycle_Homo sapiens_hsa041102.47678211
5Mismatch repair_Homo sapiens_hsa034302.32039262
6Spliceosome_Homo sapiens_hsa030402.26319845
7Ribosome_Homo sapiens_hsa030102.24454330
8mRNA surveillance pathway_Homo sapiens_hsa030152.11773935
9Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.01111603
102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.00403968
11Base excision repair_Homo sapiens_hsa034101.82959127
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.81981161
13p53 signaling pathway_Homo sapiens_hsa041151.81028813
14Fanconi anemia pathway_Homo sapiens_hsa034601.80260503
15Nucleotide excision repair_Homo sapiens_hsa034201.72399977
16One carbon pool by folate_Homo sapiens_hsa006701.70451994
17Systemic lupus erythematosus_Homo sapiens_hsa053221.70073882
18Pancreatic cancer_Homo sapiens_hsa052121.66022027
19Homologous recombination_Homo sapiens_hsa034401.65614601
20RNA degradation_Homo sapiens_hsa030181.60494714
21Pentose phosphate pathway_Homo sapiens_hsa000301.51905255
22Basal transcription factors_Homo sapiens_hsa030221.51557189
23B cell receptor signaling pathway_Homo sapiens_hsa046621.49757326
24Circadian rhythm_Homo sapiens_hsa047101.49336851
25Viral carcinogenesis_Homo sapiens_hsa052031.42128551
26Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.38710672
27Small cell lung cancer_Homo sapiens_hsa052221.36449803
28Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.35299229
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.26345864
30Vitamin B6 metabolism_Homo sapiens_hsa007501.23064116
31Adherens junction_Homo sapiens_hsa045201.21072704
32Antigen processing and presentation_Homo sapiens_hsa046121.20657400
33Oocyte meiosis_Homo sapiens_hsa041141.20057650
34FoxO signaling pathway_Homo sapiens_hsa040681.19960778
35Central carbon metabolism in cancer_Homo sapiens_hsa052301.19109057
36Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.17182048
37Glucagon signaling pathway_Homo sapiens_hsa049221.14878253
38HTLV-I infection_Homo sapiens_hsa051661.14697049
39Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.14673563
40Malaria_Homo sapiens_hsa051441.13449237
41Osteoclast differentiation_Homo sapiens_hsa043801.13158240
42MicroRNAs in cancer_Homo sapiens_hsa052061.12959408
43Selenocompound metabolism_Homo sapiens_hsa004501.09754929
44Carbon metabolism_Homo sapiens_hsa012001.07819943
45Amoebiasis_Homo sapiens_hsa051461.07362315
46Biosynthesis of amino acids_Homo sapiens_hsa012301.07279305
47Proteasome_Homo sapiens_hsa030501.06993308
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.06084556
49Leishmaniasis_Homo sapiens_hsa051401.05594300
50Bladder cancer_Homo sapiens_hsa052191.04774471
51Pyrimidine metabolism_Homo sapiens_hsa002401.03988725
52Chronic myeloid leukemia_Homo sapiens_hsa052201.03860807
53Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.03849807
54Hippo signaling pathway_Homo sapiens_hsa043901.02970478
55Basal cell carcinoma_Homo sapiens_hsa052171.02562951
56Platelet activation_Homo sapiens_hsa046111.02438295
57Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.01565728
58Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.00873504
59Viral myocarditis_Homo sapiens_hsa054160.99457521
60Fatty acid biosynthesis_Homo sapiens_hsa000610.98921377
61GnRH signaling pathway_Homo sapiens_hsa049120.98339743
62Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97684729
63Endometrial cancer_Homo sapiens_hsa052130.96035856
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.95699172
65Linoleic acid metabolism_Homo sapiens_hsa005910.94986582
66Epstein-Barr virus infection_Homo sapiens_hsa051690.93774132
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.93695361
68Pyruvate metabolism_Homo sapiens_hsa006200.92586297
69Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91208410
70alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91194144
71Proteoglycans in cancer_Homo sapiens_hsa052050.90112870
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89932795
73cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89186056
74* Tight junction_Homo sapiens_hsa045300.88809274
75HIF-1 signaling pathway_Homo sapiens_hsa040660.87969382
76Non-homologous end-joining_Homo sapiens_hsa034500.87841048
77mTOR signaling pathway_Homo sapiens_hsa041500.87427561
78ECM-receptor interaction_Homo sapiens_hsa045120.87211659
79AMPK signaling pathway_Homo sapiens_hsa041520.86890813
80RNA polymerase_Homo sapiens_hsa030200.86353650
81Focal adhesion_Homo sapiens_hsa045100.85964518
82Legionellosis_Homo sapiens_hsa051340.85603747
83Galactose metabolism_Homo sapiens_hsa000520.85566904
84Dorso-ventral axis formation_Homo sapiens_hsa043200.85159393
85Glioma_Homo sapiens_hsa052140.84577826
86Herpes simplex infection_Homo sapiens_hsa051680.81976902
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.81096174
88Oxytocin signaling pathway_Homo sapiens_hsa049210.80576295
89Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80305548
90Thyroid cancer_Homo sapiens_hsa052160.79993192
91TGF-beta signaling pathway_Homo sapiens_hsa043500.79754779
92Influenza A_Homo sapiens_hsa051640.79432652
93Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78942683
94TNF signaling pathway_Homo sapiens_hsa046680.77601684
95Fructose and mannose metabolism_Homo sapiens_hsa000510.76825875
96VEGF signaling pathway_Homo sapiens_hsa043700.76608638
97Hedgehog signaling pathway_Homo sapiens_hsa043400.76443783
98Acute myeloid leukemia_Homo sapiens_hsa052210.76014628
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.75998670
100Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72815170
101Hepatitis C_Homo sapiens_hsa051600.71177169
102MAPK signaling pathway_Homo sapiens_hsa040100.70923853
103Purine metabolism_Homo sapiens_hsa002300.70550833
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.69470474
105Arginine and proline metabolism_Homo sapiens_hsa003300.68945855
106Tuberculosis_Homo sapiens_hsa051520.67482609
107Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67286030
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.66634040
109Toxoplasmosis_Homo sapiens_hsa051450.66377499
110Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66154563
111Notch signaling pathway_Homo sapiens_hsa043300.64941207
112Jak-STAT signaling pathway_Homo sapiens_hsa046300.64256842
113Cysteine and methionine metabolism_Homo sapiens_hsa002700.63489486
114Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63438835
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.62376485
116Dilated cardiomyopathy_Homo sapiens_hsa054140.61342629
117ErbB signaling pathway_Homo sapiens_hsa040120.61017649
118Apoptosis_Homo sapiens_hsa042100.59859746
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.59166497
120Measles_Homo sapiens_hsa051620.58396280
121Calcium signaling pathway_Homo sapiens_hsa040200.58036549
122Insulin resistance_Homo sapiens_hsa049310.57340969
123Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55923892
124Choline metabolism in cancer_Homo sapiens_hsa052310.55594890
125Colorectal cancer_Homo sapiens_hsa052100.55050947
126Lysine degradation_Homo sapiens_hsa003100.54497041
127Insulin signaling pathway_Homo sapiens_hsa049100.53713798
128Prostate cancer_Homo sapiens_hsa052150.53376557
129T cell receptor signaling pathway_Homo sapiens_hsa046600.53117907
130Leukocyte transendothelial migration_Homo sapiens_hsa046700.52910408
131Prolactin signaling pathway_Homo sapiens_hsa049170.51832418
132Pathways in cancer_Homo sapiens_hsa052000.50108301
133Phenylalanine metabolism_Homo sapiens_hsa003600.49560320
134Inositol phosphate metabolism_Homo sapiens_hsa005620.49150669
135Arginine biosynthesis_Homo sapiens_hsa002200.48793029
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47396782
137Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46137221
138Alcoholism_Homo sapiens_hsa050340.45638078
139Wnt signaling pathway_Homo sapiens_hsa043100.45427111
140NOD-like receptor signaling pathway_Homo sapiens_hsa046210.44775438
141Non-small cell lung cancer_Homo sapiens_hsa052230.43709907
142AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43201746
143Shigellosis_Homo sapiens_hsa051310.42760607
144Cardiac muscle contraction_Homo sapiens_hsa042600.42348166
145Renal cell carcinoma_Homo sapiens_hsa052110.41912804
146Hepatitis B_Homo sapiens_hsa051610.41361689
147Phototransduction_Homo sapiens_hsa047440.41341696

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