YIF1A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein maturation by protein folding (GO:0022417)5.86539980
2signal peptide processing (GO:0006465)4.28385133
3Golgi transport vesicle coating (GO:0048200)3.97725090
4COPI coating of Golgi vesicle (GO:0048205)3.97725090
5L-phenylalanine metabolic process (GO:0006558)3.78571269
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.78571269
7L-phenylalanine catabolic process (GO:0006559)3.71122363
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.71122363
9negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.69631140
10amino acid salvage (GO:0043102)3.65128210
11L-methionine salvage (GO:0071267)3.65128210
12L-methionine biosynthetic process (GO:0071265)3.65128210
13L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.61282443
14proteasome assembly (GO:0043248)3.53600771
15DNA deamination (GO:0045006)3.50563271
16deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.48138786
17maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.46486433
18protein retention in ER lumen (GO:0006621)3.44734590
19NADH metabolic process (GO:0006734)3.34042074
20glyoxylate metabolic process (GO:0046487)3.31923803
21nucleobase-containing small molecule interconversion (GO:0015949)3.23312535
22chaperone-mediated protein transport (GO:0072321)3.19125574
23retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.16177088
24aldehyde catabolic process (GO:0046185)3.15789208
25branched-chain amino acid catabolic process (GO:0009083)3.12662830
26nucleotide-sugar biosynthetic process (GO:0009226)3.11881159
27proline metabolic process (GO:0006560)3.11204545
28aromatic amino acid family catabolic process (GO:0009074)3.10519384
29GDP-mannose metabolic process (GO:0019673)3.10177107
30anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.04594825
31COPII vesicle coating (GO:0048208)3.00797638
32protein targeting to mitochondrion (GO:0006626)2.98430453
33mitotic nuclear envelope reassembly (GO:0007084)2.97666083
34nuclear envelope reassembly (GO:0031468)2.97666083
35antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.96896048
36signal transduction involved in DNA damage checkpoint (GO:0072422)2.96264435
37signal transduction involved in DNA integrity checkpoint (GO:0072401)2.96264435
38oxidative phosphorylation (GO:0006119)2.95410302
39serine family amino acid biosynthetic process (GO:0009070)2.94949728
40tricarboxylic acid cycle (GO:0006099)2.94906305
41mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.94646442
42positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.93405520
43regulation of cellular amino acid metabolic process (GO:0006521)2.92033705
44sulfur amino acid catabolic process (GO:0000098)2.91316505
45sulfur amino acid biosynthetic process (GO:0000097)2.88273555
46cullin deneddylation (GO:0010388)2.87833624
47signal transduction involved in cell cycle checkpoint (GO:0072395)2.86780024
48valine metabolic process (GO:0006573)2.86100570
49protein deneddylation (GO:0000338)2.85612444
50glycine metabolic process (GO:0006544)2.85243291
51guanosine-containing compound biosynthetic process (GO:1901070)2.82596630
52cellular glucuronidation (GO:0052695)2.82546429
53regulation of cellular amine metabolic process (GO:0033238)2.82105666
54nucleotide transmembrane transport (GO:1901679)2.81770287
55antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.81614860
56establishment of viral latency (GO:0019043)2.81319906
574-hydroxyproline metabolic process (GO:0019471)2.80973362
58positive regulation of ligase activity (GO:0051351)2.80815860
59L-serine metabolic process (GO:0006563)2.79533739
60negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.77918411
61methionine biosynthetic process (GO:0009086)2.76989599
62uronic acid metabolic process (GO:0006063)2.76292214
63glucuronate metabolic process (GO:0019585)2.76292214
64establishment of integrated proviral latency (GO:0075713)2.76218679
65peptidyl-histidine modification (GO:0018202)2.75869337
66branched-chain amino acid metabolic process (GO:0009081)2.75860074
67establishment of protein localization to mitochondrial membrane (GO:0090151)2.74117147
68positive regulation of cellular amine metabolic process (GO:0033240)2.73326464
69xenobiotic catabolic process (GO:0042178)2.69762221
70tryptophan metabolic process (GO:0006568)2.68931513
71establishment of protein localization to mitochondrion (GO:0072655)2.68748788
72indole-containing compound catabolic process (GO:0042436)2.68735409
73indolalkylamine catabolic process (GO:0046218)2.68735409
74tryptophan catabolic process (GO:0006569)2.68735409
75peptidyl-glutamic acid carboxylation (GO:0017187)2.68514036
76protein carboxylation (GO:0018214)2.68514036
77regulation of mitochondrial translation (GO:0070129)2.67151714
78negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.66998908
79ATP synthesis coupled proton transport (GO:0015986)2.66672108
80energy coupled proton transport, down electrochemical gradient (GO:0015985)2.66672108
81regulation of metalloenzyme activity (GO:0048552)2.66195034
82formation of translation preinitiation complex (GO:0001731)2.66126444
83purine ribonucleotide transport (GO:0015868)2.65648842
84antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.65488053
85folic acid metabolic process (GO:0046655)2.64652600
86regulation of ubiquitin-protein transferase activity (GO:0051438)2.64044525
87fatty acid beta-oxidation (GO:0006635)2.62625172
88cysteine metabolic process (GO:0006534)2.62330580
89serine family amino acid metabolic process (GO:0009069)2.61575365
90positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.60984180
91aspartate family amino acid biosynthetic process (GO:0009067)2.60628875
92amino-acid betaine metabolic process (GO:0006577)2.60511510
93triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.58877209
94rRNA modification (GO:0000154)2.58834543
95DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.58545185
96respiratory chain complex IV assembly (GO:0008535)2.58175863
97serine family amino acid catabolic process (GO:0009071)2.58141239
98purine nucleobase biosynthetic process (GO:0009113)2.56849508
99glucose catabolic process (GO:0006007)2.56613319
100methionine metabolic process (GO:0006555)2.55825246
101type B pancreatic cell proliferation (GO:0044342)2.55346203
102respiratory electron transport chain (GO:0022904)2.55227379
103protein localization to mitochondrion (GO:0070585)2.54893165
104regulation of ligase activity (GO:0051340)2.54709440
105glutamine family amino acid biosynthetic process (GO:0009084)2.54639398
106oxaloacetate metabolic process (GO:0006107)2.54630077
107cellular ketone body metabolic process (GO:0046950)2.54489701
108regulation of cholesterol esterification (GO:0010872)2.54389650
109transcription elongation from RNA polymerase III promoter (GO:0006385)2.54339559
110termination of RNA polymerase III transcription (GO:0006386)2.54339559
111mannosylation (GO:0097502)2.53657165
112fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.53211626
113mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.52397396
114proline biosynthetic process (GO:0006561)2.51843059
115intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.51502218
116signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.51502218
117pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.51430643
118signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.51366177
119signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.51366177
120signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.51366177
121dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.50516602
122regulation of cholesterol metabolic process (GO:0090181)2.49762500
123tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.49086034
124RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.49086034
125UTP biosynthetic process (GO:0006228)2.49019666
126lipopolysaccharide biosynthetic process (GO:0009103)2.48722955
127regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.48610450
128negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.48602108
129negative regulation of ligase activity (GO:0051352)2.48602108
130folic acid transport (GO:0015884)2.48571116
131electron transport chain (GO:0022900)2.48415661
132aromatic amino acid family metabolic process (GO:0009072)2.48317257
133pentose-phosphate shunt (GO:0006098)2.48143072
134positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.47989949
135pteridine-containing compound biosynthetic process (GO:0042559)2.47901399
136metallo-sulfur cluster assembly (GO:0031163)2.47356591
137iron-sulfur cluster assembly (GO:0016226)2.47356591
138base-excision repair, AP site formation (GO:0006285)2.47213499
139lysine catabolic process (GO:0006554)2.46410078
140lysine metabolic process (GO:0006553)2.46410078
141GTP biosynthetic process (GO:0006183)2.46333660
142homocysteine metabolic process (GO:0050667)2.46185190
143protein complex biogenesis (GO:0070271)2.46099156
144monosaccharide biosynthetic process (GO:0046364)2.45867691
145gluconeogenesis (GO:0006094)2.45515976
146mitochondrial respiratory chain complex I assembly (GO:0032981)2.45377598
147NADH dehydrogenase complex assembly (GO:0010257)2.45377598
148mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.45377598
149galactose catabolic process (GO:0019388)2.44689077
150nucleotide salvage (GO:0043173)2.44308536
151kynurenine metabolic process (GO:0070189)2.41877906
152aspartate family amino acid metabolic process (GO:0009066)2.41691618
153fatty acid oxidation (GO:0019395)2.41627617
154UDP-N-acetylglucosamine metabolic process (GO:0006047)2.41538401

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.43914976
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.01910174
3* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.47114118
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.37850704
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.37543955
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.36757540
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.24543363
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.03389989
9RXR_22158963_ChIP-Seq_LIVER_Mouse2.93387307
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.88365101
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.84087201
12PPARA_22158963_ChIP-Seq_LIVER_Mouse2.73654034
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.73320028
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.70087595
15EGR1_23403033_ChIP-Seq_LIVER_Mouse2.51209854
16ZNF263_19887448_ChIP-Seq_K562_Human2.48128948
17SRF_21415370_ChIP-Seq_HL-1_Mouse2.46667527
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.40842908
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.37693957
20CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.36647222
21* PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.26287995
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.18136016
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.13779062
24TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.09260299
25DCP1A_22483619_ChIP-Seq_HELA_Human2.04139766
26LXR_22158963_ChIP-Seq_LIVER_Mouse1.99416325
27IRF8_22096565_ChIP-ChIP_GC-B_Human1.98978414
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.97266109
29MYC_19030024_ChIP-ChIP_MESCs_Mouse1.92765406
30* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.90228479
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.88932385
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.88795782
33FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.87052768
34* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.86993334
35VDR_23849224_ChIP-Seq_CD4+_Human1.81384969
36HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.76558623
37HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.74743572
38TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72391398
39* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.67411403
40GABP_19822575_ChIP-Seq_HepG2_Human1.66488297
41NELFA_20434984_ChIP-Seq_ESCs_Mouse1.65849768
42RARG_19884340_ChIP-ChIP_MEFs_Mouse1.64585248
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.60883342
44FOXP3_21729870_ChIP-Seq_TREG_Human1.54858249
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54442474
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.52593886
47E2F7_22180533_ChIP-Seq_HELA_Human1.48597177
48* XRN2_22483619_ChIP-Seq_HELA_Human1.46402521
49PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.45166105
50STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.45165943
51* ELK3_25401928_ChIP-Seq_HUVEC_Human1.44473815
52HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42485123
53LXR_22292898_ChIP-Seq_THP-1_Human1.42021230
54PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41516312
55MYC_19079543_ChIP-ChIP_MESCs_Mouse1.40982872
56* RACK7_27058665_Chip-Seq_MCF-7_Human1.39022974
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.36894517
58KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.36021603
59ELK1_22589737_ChIP-Seq_MCF10A_Human1.35422945
60THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35313188
61ERG_20887958_ChIP-Seq_HPC-7_Mouse1.34652463
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.33350324
63ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.32446008
64HOXB4_20404135_ChIP-ChIP_EML_Mouse1.32395372
65TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.31235232
66ELK1_19687146_ChIP-ChIP_HELA_Human1.29952545
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.29545372
68TP63_17297297_ChIP-ChIP_HaCaT_Human1.28854879
69SRY_22984422_ChIP-ChIP_TESTIS_Rat1.26735571
70TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.23787447
71ZFX_18555785_ChIP-Seq_MESCs_Mouse1.23422973
72TRIM28_21343339_ChIP-Seq_HEK293_Human1.23376786
73ATF3_27146783_Chip-Seq_COLON_Human1.20246707
74NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.19382663
75GATA1_22025678_ChIP-Seq_K562_Human1.18085568
76CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.17689991
77* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.17205642
78HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16744323
79STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15880641
80AR_21909140_ChIP-Seq_LNCAP_Human1.15211761
81PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.14230044
82ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13848048
83SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10927021
84* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09723583
85FOXP1_21924763_ChIP-Seq_HESCs_Human1.08660103
86SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.08573849
87ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.07762632
88* TBX5_21415370_ChIP-Seq_HL-1_Mouse1.05341833
89NANOG_18555785_ChIP-Seq_MESCs_Mouse1.04782025
90CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.03773736
91* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03715345
92CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02286362
93ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.02197340
94TFEB_21752829_ChIP-Seq_HELA_Human1.02123179
95SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.01580322
96ELF1_20517297_ChIP-Seq_JURKAT_Human1.01553506
97TTF2_22483619_ChIP-Seq_HELA_Human1.01237140
98FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.98591209
99* MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97857339
100PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.97199194
101* SOX17_20123909_ChIP-Seq_XEN_Mouse0.94991426
102E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.90975305
103CLOCK_20551151_ChIP-Seq_293T_Human0.89264807
104SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.88373135
105* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.88344583
106MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.87366508
107PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87180944
108* POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.87006549
109* IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.86183204
110MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.84805716
111SOX2_18692474_ChIP-Seq_MEFs_Mouse0.81691636
112DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81481678
113KDM5A_27292631_Chip-Seq_BREAST_Human0.79315252
114* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.78432753
115GATA4_21415370_ChIP-Seq_HL-1_Mouse0.77538077
116POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.76476027
117ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.76192165
118KLF4_18555785_ChIP-Seq_MESCs_Mouse0.75890211
119SPI1_23547873_ChIP-Seq_NB4_Human0.75308197
120* TET1_21451524_ChIP-Seq_MESCs_Mouse0.75217515
121NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.74116823
122* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.73895009
123GATA1_22383799_ChIP-Seq_G1ME_Mouse0.73606763

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis4.86865035
2MP0002139_abnormal_hepatobiliary_system4.51282157
3MP0005360_urolithiasis3.56980932
4MP0005085_abnormal_gallbladder_physiolo3.19919524
5MP0005365_abnormal_bile_salt3.18725369
6MP0003195_calcinosis3.08571659
7MP0009840_abnormal_foam_cell3.04357527
8MP0003186_abnormal_redox_activity3.03470744
9MP0004272_abnormal_basement_membrane2.89642159
10MP0008438_abnormal_cutaneous_collagen2.85113826
11MP0008875_abnormal_xenobiotic_pharmacok2.67131807
12MP0005332_abnormal_amino_acid2.17749706
13MP0001764_abnormal_homeostasis2.09696487
14MP0005257_abnormal_intraocular_pressure2.05440655
15MP0010030_abnormal_orbit_morphology2.00681717
16MP0001666_abnormal_nutrient_absorption1.92414301
17MP0005083_abnormal_biliary_tract1.89519943
18MP0003191_abnormal_cellular_cholesterol1.84357569
19MP0006036_abnormal_mitochondrial_physio1.77615630
20MP0003656_abnormal_erythrocyte_physiolo1.75411806
21MP0009697_abnormal_copulation1.71791427
22MP0001542_abnormal_bone_strength1.70279744
23MP0005058_abnormal_lysosome_morphology1.65194013
24MP0004858_abnormal_nervous_system1.64869394
25MP0004233_abnormal_muscle_weight1.63291895
26MP0003693_abnormal_embryo_hatching1.62300386
27MP0003566_abnormal_cell_adhesion1.60221265
28MP0009643_abnormal_urine_homeostasis1.59369360
29MP0010329_abnormal_lipoprotein_level1.59083743
30MP0003941_abnormal_skin_development1.58293060
31MP0005503_abnormal_tendon_morphology1.58149118
32MP0005319_abnormal_enzyme/_coenzyme1.53853382
33MP0010234_abnormal_vibrissa_follicle1.52286292
34MP0003011_delayed_dark_adaptation1.51548770
35MP0008932_abnormal_embryonic_tissue1.48658593
36MP0002254_reproductive_system_inflammat1.45759323
37MP0005084_abnormal_gallbladder_morpholo1.44688182
38MP0005220_abnormal_exocrine_pancreas1.43500011
39MP0004019_abnormal_vitamin_homeostasis1.42752905
40MP0005623_abnormal_meninges_morphology1.40776477
41MP0003252_abnormal_bile_duct1.40146228
42MP0005275_abnormal_skin_tensile1.38139095
43MP0003111_abnormal_nucleus_morphology1.36773614
44MP0006054_spinal_hemorrhage1.34696738
45MP0001756_abnormal_urination1.33446650
46MP0000003_abnormal_adipose_tissue1.32408754
47MP0000751_myopathy1.32356246
48MP0000609_abnormal_liver_physiology1.31133492
49MP0003123_paternal_imprinting1.29973552
50MP0005501_abnormal_skin_physiology1.29159211
51MP0003786_premature_aging1.28214256
52MP0008007_abnormal_cellular_replicative1.27481391
53MP0003279_aneurysm1.23425480
54MP0002118_abnormal_lipid_homeostasis1.22259608
55MP0003718_maternal_effect1.22022825
56MP0002837_dystrophic_cardiac_calcinosis1.21342497
57MP0002132_abnormal_respiratory_system1.14826586
58MP0003646_muscle_fatigue1.13649666
59MP0005636_abnormal_mineral_homeostasis1.12417544
60MP0005584_abnormal_enzyme/coenzyme_acti1.12334417
61MP0002933_joint_inflammation1.11962108
62MP0000749_muscle_degeneration1.08972589
63MP0005451_abnormal_body_composition1.07390868
64MP0000750_abnormal_muscle_regeneration1.07264183
65MP0008058_abnormal_DNA_repair1.07239291
66MP0009384_cardiac_valve_regurgitation1.07008287
67MP0005408_hypopigmentation1.06196129
68MP0002796_impaired_skin_barrier1.06021834
69MP0004043_abnormal_pH_regulation1.02813991
70MP0004782_abnormal_surfactant_physiolog1.02611665
71MP0009333_abnormal_splenocyte_physiolog1.02308847
72MP0008469_abnormal_protein_level1.01128202
73MP0000598_abnormal_liver_morphology0.99954378
74MP0006035_abnormal_mitochondrial_morpho0.99810680
75MP0001730_embryonic_growth_arrest0.99561230
76MP0000538_abnormal_urinary_bladder0.99036521
77MP0002295_abnormal_pulmonary_circulatio0.98095032
78MP0000013_abnormal_adipose_tissue0.98010549
79MP0010368_abnormal_lymphatic_system0.97419069
80MP0000462_abnormal_digestive_system0.96700567
81MP0002138_abnormal_hepatobiliary_system0.96322280
82MP0001881_abnormal_mammary_gland0.95881485
83MP0000516_abnormal_urinary_system0.95782260
84MP0005367_renal/urinary_system_phenotyp0.95782260
85MP0010386_abnormal_urinary_bladder0.95261978
86MP0003705_abnormal_hypodermis_morpholog0.93557053
87MP0003077_abnormal_cell_cycle0.92205463
88MP0005376_homeostasis/metabolism_phenot0.91563882
89MP0005165_increased_susceptibility_to0.91382190
90MP0000372_irregular_coat_pigmentation0.91295108
91MP0003950_abnormal_plasma_membrane0.91219313
92MP0002876_abnormal_thyroid_physiology0.90314700
93MP0005670_abnormal_white_adipose0.88608452
94MP0002877_abnormal_melanocyte_morpholog0.88141819
95MP0003724_increased_susceptibility_to0.87260427
96MP0002060_abnormal_skin_morphology0.86764421
97MP0005023_abnormal_wound_healing0.86000076
98MP0001533_abnormal_skeleton_physiology0.85453501
99MP0000678_abnormal_parathyroid_gland0.85171393
100MP0004957_abnormal_blastocyst_morpholog0.85159006
101MP0008260_abnormal_autophagy0.84707459
102MP0000343_altered_response_to0.83571167
103MP0001243_abnormal_dermal_layer0.83483927
104MP0005266_abnormal_metabolism0.83156742
105MP0003868_abnormal_feces_composition0.82867934
106MP0003315_abnormal_perineum_morphology0.82864336
107MP0000467_abnormal_esophagus_morphology0.82555572
108MP0005330_cardiomyopathy0.80585136
109MP0010771_integument_phenotype0.80350003
110MP0004147_increased_porphyrin_level0.80290139
111MP0002163_abnormal_gland_morphology0.79772459
112MP0003436_decreased_susceptibility_to0.79164853
113MP0005395_other_phenotype0.77565465
114MP0000747_muscle_weakness0.76031594
115MP0009785_altered_susceptibility_to0.75679433
116MP0002080_prenatal_lethality0.75142224
117MP0001915_intracranial_hemorrhage0.75103748
118MP0001849_ear_inflammation0.73605725
119MP0000537_abnormal_urethra_morphology0.72710331
120MP0005379_endocrine/exocrine_gland_phen0.72459820
121MP0000358_abnormal_cell_content/0.72305828
122MP0001727_abnormal_embryo_implantation0.72157939
123MP0000762_abnormal_tongue_morphology0.71884341
124MP0001958_emphysema0.71445873
125MP0009780_abnormal_chondrocyte_physiolo0.70305459
126MP0004084_abnormal_cardiac_muscle0.70166133
127MP0009763_increased_sensitivity_to0.69867037
128MP0009764_decreased_sensitivity_to0.69834749
129MP0002089_abnormal_postnatal_growth/wei0.69466926
130MP0009642_abnormal_blood_homeostasis0.69431491
131MP0005390_skeleton_phenotype0.68934706
132MP0002136_abnormal_kidney_physiology0.66438529
133MP0002078_abnormal_glucose_homeostasis0.64546515
134MP0005508_abnormal_skeleton_morphology0.64109249
135MP0001845_abnormal_inflammatory_respons0.64070865
136MP0000163_abnormal_cartilage_morphology0.63296583
137MP0002148_abnormal_hypersensitivity_rea0.61675208
138MP0004134_abnormal_chest_morphology0.61162166
139MP0006082_CNS_inflammation0.60684543
140MP0001853_heart_inflammation0.60369150
141MP0000230_abnormal_systemic_arterial0.59390449
142MP0003795_abnormal_bone_structure0.58878473
143MP0001661_extended_life_span0.57246189
144MP0002693_abnormal_pancreas_physiology0.57221956
145MP0001944_abnormal_pancreas_morphology0.56320048
146MP0002419_abnormal_innate_immunity0.54445775
147MP0002269_muscular_atrophy0.53843604

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)3.82668182
2Hepatic necrosis (HP:0002605)3.80677923
3Hypoglycemic coma (HP:0001325)3.77871100
4Generalized aminoaciduria (HP:0002909)3.54235163
5Abnormality of fatty-acid metabolism (HP:0004359)3.28072250
6Testicular atrophy (HP:0000029)3.23720979
7Abnormality of dicarboxylic acid metabolism (HP:0010995)3.19141550
8Dicarboxylic aciduria (HP:0003215)3.19141550
9Hepatocellular necrosis (HP:0001404)3.17121821
10Acute encephalopathy (HP:0006846)3.15688226
11Cholecystitis (HP:0001082)3.08051664
12Abnormal gallbladder physiology (HP:0012438)3.08051664
13Acute necrotizing encephalopathy (HP:0006965)3.06215986
14Abnormal tarsal ossification (HP:0008369)3.04449528
15Intrahepatic cholestasis (HP:0001406)2.97908328
16Hyperglycinemia (HP:0002154)2.97879298
17Abnormal mitochondria in muscle tissue (HP:0008316)2.97644530
18Mitochondrial inheritance (HP:0001427)2.93829063
19Beaking of vertebral bodies (HP:0004568)2.88592351
20Abnormality of the intrinsic pathway (HP:0010989)2.87952971
21Xanthomatosis (HP:0000991)2.87924568
22Hyperglycinuria (HP:0003108)2.85853452
23Cerebral edema (HP:0002181)2.83828219
24Irregular epiphyses (HP:0010582)2.81479698
25Increased CSF lactate (HP:0002490)2.77734986
26Prolonged partial thromboplastin time (HP:0003645)2.77218903
27Abnormality of monocarboxylic acid metabolism (HP:0010996)2.77217984
28Hypobetalipoproteinemia (HP:0003563)2.74609480
29Hyperammonemia (HP:0001987)2.73781897
30Lethargy (HP:0001254)2.73563548
31Proximal tubulopathy (HP:0000114)2.67458125
32Hypokinesia (HP:0002375)2.66228665
33Trismus (HP:0000211)2.62371417
34Abnormality of serine family amino acid metabolism (HP:0010894)2.62123461
35Abnormality of glycine metabolism (HP:0010895)2.62123461
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.61924214
37Nausea (HP:0002018)2.51742202
38Abnormality of urine glucose concentration (HP:0011016)2.51122592
39Glycosuria (HP:0003076)2.51122592
40Type I transferrin isoform profile (HP:0003642)2.48918251
41Rough bone trabeculation (HP:0100670)2.46344471
42Increased serum lactate (HP:0002151)2.46042667
43Reduced antithrombin III activity (HP:0001976)2.43826366
44Microretrognathia (HP:0000308)2.43044178
45Vertebral compression fractures (HP:0002953)2.42656704
46Abnormality of the Achilles tendon (HP:0005109)2.42123160
47Lactic acidosis (HP:0003128)2.41537465
48Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.40388534
49Decreased activity of mitochondrial respiratory chain (HP:0008972)2.40388534
50Achilles tendon contracture (HP:0001771)2.40207718
51Ketosis (HP:0001946)2.40203125
52Hypolipoproteinemia (HP:0010981)2.38883875
53Abnormality of the umbilical cord (HP:0010881)2.37711891
54Ragged-red muscle fibers (HP:0003200)2.37678008
55Abnormality of serum amino acid levels (HP:0003112)2.37164555
56Fat malabsorption (HP:0002630)2.33809639
57Progressive macrocephaly (HP:0004481)2.32734365
58Opisthotonus (HP:0002179)2.31559869
59Abnormality of methionine metabolism (HP:0010901)2.29826110
60Vacuolated lymphocytes (HP:0001922)2.27088837
61Nonimmune hydrops fetalis (HP:0001790)2.26457493
62CNS demyelination (HP:0007305)2.25432399
63Abnormal protein glycosylation (HP:0012346)2.23988647
64Abnormal glycosylation (HP:0012345)2.23988647
65Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.23988647
66Abnormal protein N-linked glycosylation (HP:0012347)2.23988647
67Abnormality of aspartate family amino acid metabolism (HP:0010899)2.22974165
68Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.21850330
69Cervical subluxation (HP:0003308)2.21010397
70Hypoalphalipoproteinemia (HP:0003233)2.20677945
71Abnormal cartilage morphology (HP:0002763)2.19632551
72Lipid accumulation in hepatocytes (HP:0006561)2.18880089
73Renal Fanconi syndrome (HP:0001994)2.16584740
74Steatorrhea (HP:0002570)2.16233138
75Increased muscle lipid content (HP:0009058)2.15732048
76Respiratory failure (HP:0002878)2.15496081
77Ketoacidosis (HP:0001993)2.11330895
78Vomiting (HP:0002013)2.10623958
79Increased serum pyruvate (HP:0003542)2.10061082
80Abnormality of glycolysis (HP:0004366)2.10061082
81Abnormal foot bone ossification (HP:0010675)2.09423244
823-Methylglutaconic aciduria (HP:0003535)2.09286915
83Abnormalities of placenta or umbilical cord (HP:0001194)2.09264789
84Generalized amyotrophy (HP:0003700)2.09027809
85Abnormality of the common coagulation pathway (HP:0010990)2.08026317
86Flat capital femoral epiphysis (HP:0003370)2.07929490
87Premature rupture of membranes (HP:0001788)2.07389107
88Hyperlipoproteinemia (HP:0010980)2.05641526
89Cupped ribs (HP:0000887)2.04679015
90Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.04176049
91Methylmalonic aciduria (HP:0012120)2.03408643
92Abnormality of glycosphingolipid metabolism (HP:0004343)2.02636661
93Abnormality of glycolipid metabolism (HP:0010969)2.02636661
94Abnormality of liposaccharide metabolism (HP:0010968)2.02636661
95Metabolic acidosis (HP:0001942)2.02622150
96Abnormality of dentin (HP:0010299)2.02619646
97Abnormality of sulfur amino acid metabolism (HP:0004339)2.01320878
98Multiple enchondromatosis (HP:0005701)2.00281875
99Increased intramyocellular lipid droplets (HP:0012240)2.00190007
100Abnormal trabecular bone morphology (HP:0100671)2.00140360
101Hypoglycemic seizures (HP:0002173)1.99782778
102Abnormal delivery (HP:0001787)1.99499620
103Exercise intolerance (HP:0003546)1.99238367
104Abnormality of glutamine family amino acid metabolism (HP:0010902)1.96386801
105Prolonged neonatal jaundice (HP:0006579)1.95871026
106Carpal bone hypoplasia (HP:0001498)1.95783685
107Hyperbilirubinemia (HP:0002904)1.95645103
108Delayed epiphyseal ossification (HP:0002663)1.95507707
109Abnormality of the distal phalanges of the toes (HP:0010182)1.94360717
110Deep venous thrombosis (HP:0002625)1.94212774
111Breech presentation (HP:0001623)1.94092364
112Upper limb amyotrophy (HP:0009129)1.94071158
113Distal upper limb amyotrophy (HP:0007149)1.94071158
114Protrusio acetabuli (HP:0003179)1.93545446
115Poor head control (HP:0002421)1.93542471
116Cardiovascular calcification (HP:0011915)1.93400503
117Sparse eyelashes (HP:0000653)1.93157169
118Gout (HP:0001997)1.92890903
119Protuberant abdomen (HP:0001538)1.92111497
120Short nail (HP:0001799)1.92037334
121Elbow flexion contracture (HP:0002987)1.90121884
122Increased hepatocellular lipid droplets (HP:0006565)1.89410816
123Redundant skin (HP:0001582)1.87881944
124Vascular calcification (HP:0004934)1.87244934
125Biconcave vertebral bodies (HP:0004586)1.86884573
126Progressive muscle weakness (HP:0003323)1.86101418
127Secondary amenorrhea (HP:0000869)1.85910122
128Microvesicular hepatic steatosis (HP:0001414)1.85859927
129Renal cortical cysts (HP:0000803)1.85561234
130Spastic paraparesis (HP:0002313)1.85324686
131Rhabdomyolysis (HP:0003201)1.84535854
132Abnormality of carpal bone ossification (HP:0006257)1.83628892
133Irregular vertebral endplates (HP:0003301)1.82349120
134Cholelithiasis (HP:0001081)1.81967180
135Abnormality of the fetal cardiovascular system (HP:0010948)1.81908956
136Abnormal umbilical cord blood vessels (HP:0011403)1.81908956
137Single umbilical artery (HP:0001195)1.81908956
138Respiratory distress (HP:0002098)1.81028635
139Atrophic scars (HP:0001075)1.80481305
140Distal lower limb muscle weakness (HP:0009053)1.80017926
141Abnormal gallbladder morphology (HP:0012437)1.79110121
142Ankle contracture (HP:0006466)1.76677836
143Hand muscle atrophy (HP:0009130)1.76228340
144Blue sclerae (HP:0000592)1.74201146
145Reduced subcutaneous adipose tissue (HP:0003758)1.72397455

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.30924853
2VRK23.69964786
3NME23.69656085
4EIF2AK13.24800902
5PIM23.20967229
6STK163.05421122
7EIF2AK32.65575640
8IRAK32.47235003
9ERN12.34966036
10BUB12.28306259
11PAK42.13929024
12NEK92.06612213
13TESK12.04271337
14MAP3K31.98850707
15MYLK1.88059324
16EPHA21.87255228
17PBK1.84828899
18MAPK151.84086194
19FLT31.74460607
20STK38L1.72518092
21SMG11.69775228
22BRSK21.65386484
23KDR1.64889502
24ZAK1.59450374
25MAP3K121.57532938
26ARAF1.52002439
27MST41.41368865
28BRAF1.40281852
29LIMK11.35572782
30PTK21.34859077
31WEE11.33009707
32PIK3CG1.32770717
33OBSCN1.30037526
34TESK21.29153864
35PLK41.28835207
36MAP3K111.26604455
37ABL21.22625782
38PRKCI1.19524982
39LMTK21.19261388
40AKT31.16590730
41NME11.12550560
42SIK11.03661115
43VRK11.03424728
44DAPK11.02617604
45MUSK1.02012399
46PINK11.00868596
47MAP3K140.93828021
48PASK0.93323840
49PDK20.93287189
50EIF2AK20.92274729
51TBK10.91124676
52TEC0.88910452
53IRAK40.88022626
54STK240.87230790
55ERBB30.85360324
56IRAK10.84301612
57TLK10.83637632
58TAOK20.83133141
59TAOK10.83132235
60SRPK10.82810804
61MAPKAPK30.81011737
62CDK70.79904850
63PRKD20.79597709
64CAMK2G0.79252572
65ACVR1B0.75314526
66MAP2K30.74777979
67CSNK1G30.73824894
68ILK0.73440105
69IKBKB0.71645974
70RPS6KA40.71021785
71MST1R0.70957626
72INSRR0.70877152
73ERBB40.69539408
74TRPM70.68415503
75PDK30.67145981
76PDK40.67145981
77TTK0.66963319
78TYK20.65948668
79NLK0.65337276
80FGFR40.63308674
81BRSK10.62463607
82PRKG20.61680889
83EPHB20.61595939
84TRIB30.60733172
85CLK10.60206420
86ICK0.59511273
87ZAP700.55575031
88AKT20.55443010
89PKN20.54652647
90RAF10.54047190
91AURKA0.53274336
92LRRK20.52851745
93MET0.52427283
94MAP2K20.52007532
95PIK3CA0.51852306
96WNK40.51669343
97EPHA30.49831608
98CSNK1A1L0.49688259
99AURKB0.48816118
100BTK0.48487226
101PAK20.48186453
102CSNK1G10.47780095
103RPS6KB20.47636629
104STK40.47388771
105NEK10.47054010
106PTK60.45685797
107FRK0.44674827
108CSNK2A10.43569103
109CDC70.43479612
110RPS6KA50.42093088
111DAPK30.41415044
112MAPK110.41041443
113PIM10.40405963
114CSNK2A20.40242307
115CAMK2D0.40123059
116SCYL20.40094997
117BMPR20.39823731
118PRKCD0.37676747
119TSSK60.37670957
120MAP3K50.37185267
121PAK10.37144108
122PDGFRA0.36793487
123DYRK20.36447603
124TTN0.36417738
125FER0.36079440
126PRKD30.35956578
127PLK10.34090840
128MAPKAPK20.34075305
129MTOR0.33846639
130BMPR1B0.33834894
131CDK80.33811423
132TIE10.33080656
133MAP3K80.31824325
134PHKG10.30823438
135PHKG20.30823438
136CHEK20.30720042
137CAMKK20.30199484
138PLK30.28236065
139CCNB10.28147746
140GSK3A0.27046829
141STK100.26979231
142BMX0.26407559
143EPHB10.25816186

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.02019955
2Proteasome_Homo sapiens_hsa030502.83216305
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.20122924
4Folate biosynthesis_Homo sapiens_hsa007902.19082294
5Sulfur metabolism_Homo sapiens_hsa009202.16574285
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.13264481
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.03767125
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.92146715
9Oxidative phosphorylation_Homo sapiens_hsa001901.90567720
10Pentose and glucuronate interconversions_Homo sapiens_hsa000401.90254800
11Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.88884353
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.88406602
13Fatty acid degradation_Homo sapiens_hsa000711.87930343
14Primary bile acid biosynthesis_Homo sapiens_hsa001201.84489632
15Ribosome_Homo sapiens_hsa030101.77633666
16Propanoate metabolism_Homo sapiens_hsa006401.70823833
17Peroxisome_Homo sapiens_hsa041461.70412951
18Parkinsons disease_Homo sapiens_hsa050121.67581482
19Sulfur relay system_Homo sapiens_hsa041221.65845534
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.65246922
21Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.65069831
22Drug metabolism - other enzymes_Homo sapiens_hsa009831.60873772
23Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.57482841
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.56274028
25RNA polymerase_Homo sapiens_hsa030201.51933914
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.50467392
27Fatty acid elongation_Homo sapiens_hsa000621.48343196
28Tryptophan metabolism_Homo sapiens_hsa003801.46903522
29Glutathione metabolism_Homo sapiens_hsa004801.44926422
30Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.44049345
31Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.42589203
32Carbon metabolism_Homo sapiens_hsa012001.40564816
33Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.38854641
34Chemical carcinogenesis_Homo sapiens_hsa052041.38685955
35Selenocompound metabolism_Homo sapiens_hsa004501.36640768
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.36332111
37Butanoate metabolism_Homo sapiens_hsa006501.35902353
38Vibrio cholerae infection_Homo sapiens_hsa051101.34843292
39Pyrimidine metabolism_Homo sapiens_hsa002401.34688877
40Steroid biosynthesis_Homo sapiens_hsa001001.29448824
41Fatty acid metabolism_Homo sapiens_hsa012121.27535506
42Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.27490602
43beta-Alanine metabolism_Homo sapiens_hsa004101.26342360
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.25397610
45One carbon pool by folate_Homo sapiens_hsa006701.24048923
46Pentose phosphate pathway_Homo sapiens_hsa000301.21914204
47Histidine metabolism_Homo sapiens_hsa003401.19083521
48Pyruvate metabolism_Homo sapiens_hsa006201.18080208
49Arginine and proline metabolism_Homo sapiens_hsa003301.16787082
50Galactose metabolism_Homo sapiens_hsa000521.16688365
51Cysteine and methionine metabolism_Homo sapiens_hsa002701.16312329
52Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.14548121
53Starch and sucrose metabolism_Homo sapiens_hsa005001.13899157
54Biosynthesis of amino acids_Homo sapiens_hsa012301.10836383
55Fat digestion and absorption_Homo sapiens_hsa049751.06767933
56Huntingtons disease_Homo sapiens_hsa050161.05518585
57Caffeine metabolism_Homo sapiens_hsa002321.05513493
58Complement and coagulation cascades_Homo sapiens_hsa046101.02610008
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.99377109
60Retinol metabolism_Homo sapiens_hsa008300.98905146
61Phenylalanine metabolism_Homo sapiens_hsa003600.98396548
62Steroid hormone biosynthesis_Homo sapiens_hsa001400.98322832
63Fructose and mannose metabolism_Homo sapiens_hsa000510.97370807
64DNA replication_Homo sapiens_hsa030300.97272093
65PPAR signaling pathway_Homo sapiens_hsa033200.96697470
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.96100545
67Other glycan degradation_Homo sapiens_hsa005110.94078999
68Alzheimers disease_Homo sapiens_hsa050100.93031760
69Arachidonic acid metabolism_Homo sapiens_hsa005900.90787062
70Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.89735424
71Metabolic pathways_Homo sapiens_hsa011000.89286004
72Vitamin B6 metabolism_Homo sapiens_hsa007500.88796485
73Arginine biosynthesis_Homo sapiens_hsa002200.88673787
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88068457
75Vitamin digestion and absorption_Homo sapiens_hsa049770.87545643
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86271427
77Cyanoamino acid metabolism_Homo sapiens_hsa004600.85352790
78Tyrosine metabolism_Homo sapiens_hsa003500.81184466
79Base excision repair_Homo sapiens_hsa034100.80325138
80Regulation of autophagy_Homo sapiens_hsa041400.80144954
81Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.74896281
82Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.73749425
83Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.72409759
84Spliceosome_Homo sapiens_hsa030400.72369681
85N-Glycan biosynthesis_Homo sapiens_hsa005100.70236890
86Homologous recombination_Homo sapiens_hsa034400.63478362
87Linoleic acid metabolism_Homo sapiens_hsa005910.59550011
88Purine metabolism_Homo sapiens_hsa002300.59226064
89Lysosome_Homo sapiens_hsa041420.58959730
90Nucleotide excision repair_Homo sapiens_hsa034200.58696755
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54262725
92Non-homologous end-joining_Homo sapiens_hsa034500.52508887
93Fatty acid biosynthesis_Homo sapiens_hsa000610.52472831
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.50320174
95Legionellosis_Homo sapiens_hsa051340.48187712
96Mismatch repair_Homo sapiens_hsa034300.47776654
97Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45954937
98Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43019742
99Staphylococcus aureus infection_Homo sapiens_hsa051500.43015282
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41620908
101Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39459197
102Collecting duct acid secretion_Homo sapiens_hsa049660.37609829
103Renin-angiotensin system_Homo sapiens_hsa046140.37588193
104Sphingolipid metabolism_Homo sapiens_hsa006000.36278333
105RNA transport_Homo sapiens_hsa030130.31108829
106ABC transporters_Homo sapiens_hsa020100.29852771
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.29555955
108Protein digestion and absorption_Homo sapiens_hsa049740.29049761
109Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27487234
110Bladder cancer_Homo sapiens_hsa052190.25945892
111Cardiac muscle contraction_Homo sapiens_hsa042600.25516520
112Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.25378293
113Prion diseases_Homo sapiens_hsa050200.24935982

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