YIF1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.29257948
2ribosomal small subunit assembly (GO:0000028)5.48599794
3maturation of SSU-rRNA (GO:0030490)5.16637633
4proteasome assembly (GO:0043248)4.73776489
5protein maturation by protein folding (GO:0022417)4.62993504
6formation of translation preinitiation complex (GO:0001731)4.53055015
7telomere maintenance via semi-conservative replication (GO:0032201)4.35548439
8nucleobase biosynthetic process (GO:0046112)4.35358441
9pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.30880657
10DNA strand elongation involved in DNA replication (GO:0006271)4.30690910
11purine nucleobase biosynthetic process (GO:0009113)4.21100143
12viral transcription (GO:0019083)4.20852421
13pyrimidine deoxyribonucleotide metabolic process (GO:0009219)4.17629604
14ribosomal small subunit biogenesis (GO:0042274)4.15642841
15negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.14140390
16SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.12557028
17translational termination (GO:0006415)4.11234688
18pseudouridine synthesis (GO:0001522)4.07993351
19DNA strand elongation (GO:0022616)4.07405883
20cotranslational protein targeting to membrane (GO:0006613)4.01233756
21protein targeting to ER (GO:0045047)3.99269319
22DNA replication initiation (GO:0006270)3.94829052
23translational elongation (GO:0006414)3.92881751
24protein localization to endoplasmic reticulum (GO:0070972)3.84967592
25regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.83503359
26deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.82922115
27positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.82902655
28negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.81409665
29negative regulation of ligase activity (GO:0051352)3.81409665
30regulation of cellular amino acid metabolic process (GO:0006521)3.81212538
31cullin deneddylation (GO:0010388)3.78366584
32establishment of protein localization to endoplasmic reticulum (GO:0072599)3.76478877
33anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.74090466
34peptidyl-arginine omega-N-methylation (GO:0035247)3.73536955
35protein deneddylation (GO:0000338)3.73126029
36telomere maintenance via recombination (GO:0000722)3.72014652
37translation (GO:0006412)3.71817765
38antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.71568148
39translational initiation (GO:0006413)3.69393939
40ribonucleoprotein complex biogenesis (GO:0022613)3.68274470
41L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.67568369
42DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.67258241
43ribosome biogenesis (GO:0042254)3.63912756
44protein neddylation (GO:0045116)3.60227133
45signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.59963682
46signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.59963682
47signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.59963682
48intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.59960273
49signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.59960273
502-deoxyribonucleotide biosynthetic process (GO:0009265)3.57937758
51deoxyribose phosphate biosynthetic process (GO:0046385)3.57937758
52termination of RNA polymerase III transcription (GO:0006386)3.57656641
53transcription elongation from RNA polymerase III promoter (GO:0006385)3.57656641
54ribosomal large subunit biogenesis (GO:0042273)3.56768156
55DNA replication checkpoint (GO:0000076)3.54256251
56pyrimidine nucleotide catabolic process (GO:0006244)3.53507217
57signal transduction involved in DNA damage checkpoint (GO:0072422)3.50797044
58signal transduction involved in DNA integrity checkpoint (GO:0072401)3.50797044
59proline biosynthetic process (GO:0006561)3.50530660
60antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.50055684
61base-excision repair, AP site formation (GO:0006285)3.49102348
62deoxyribonucleotide catabolic process (GO:0009264)3.46493173
63pentose metabolic process (GO:0019321)3.45476427
64rRNA modification (GO:0000154)3.44014994
65signal transduction involved in cell cycle checkpoint (GO:0072395)3.43361618
66GMP metabolic process (GO:0046037)3.38219285
67metallo-sulfur cluster assembly (GO:0031163)3.36228939
68iron-sulfur cluster assembly (GO:0016226)3.36228939
69positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.34633487
70rRNA processing (GO:0006364)3.33947727
71deoxyribose phosphate catabolic process (GO:0046386)3.33480860
72regulation of mitochondrial translation (GO:0070129)3.30592095
73ribosome assembly (GO:0042255)3.30125168
74mitochondrial calcium ion transport (GO:0006851)3.26208360
75viral life cycle (GO:0019058)3.26084338
76spliceosomal snRNP assembly (GO:0000387)3.25844623
77negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.25755812
78positive regulation of ligase activity (GO:0051351)3.25062518
79L-methionine salvage (GO:0071267)3.24842088
80L-methionine biosynthetic process (GO:0071265)3.24842088
81amino acid salvage (GO:0043102)3.24842088
82mitotic recombination (GO:0006312)3.23941069
83histone arginine methylation (GO:0034969)3.22331857
84cellular component biogenesis (GO:0044085)3.22124659
85cellular protein complex disassembly (GO:0043624)3.21908869
86nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.20643410
87mitochondrial respiratory chain complex I assembly (GO:0032981)3.20346141
88NADH dehydrogenase complex assembly (GO:0010257)3.20346141
89mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.20346141
90rRNA metabolic process (GO:0016072)3.19596218
91protein complex biogenesis (GO:0070271)3.19494826
92guanosine-containing compound biosynthetic process (GO:1901070)3.19329082
93telomere maintenance via telomere lengthening (GO:0010833)3.19283472
94respiratory electron transport chain (GO:0022904)3.16471640
95folic acid metabolic process (GO:0046655)3.15637383
962-deoxyribonucleotide metabolic process (GO:0009394)3.15538252
97GDP-mannose metabolic process (GO:0019673)3.14604138
98transcription-coupled nucleotide-excision repair (GO:0006283)3.14409344
99IMP biosynthetic process (GO:0006188)3.14176679
100nucleotide-excision repair, DNA gap filling (GO:0006297)3.13673940
101mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.12933358
102electron transport chain (GO:0022900)3.11695129
103mitochondrial respiratory chain complex assembly (GO:0033108)3.11680539
104oxidative phosphorylation (GO:0006119)3.11200122
105G1/S transition of mitotic cell cycle (GO:0000082)3.10228616
106cell cycle G1/S phase transition (GO:0044843)3.10228616
107pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.09123555
108heme biosynthetic process (GO:0006783)3.09024784
109deoxyribose phosphate metabolic process (GO:0019692)3.08434413
110nuclear envelope reassembly (GO:0031468)3.07028284
111mitotic nuclear envelope reassembly (GO:0007084)3.07028284
112regulation of ubiquitin-protein transferase activity (GO:0051438)3.03431054
113protoporphyrinogen IX metabolic process (GO:0046501)3.02059561
114deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.01255264
115nucleobase-containing small molecule interconversion (GO:0015949)3.01028512
116negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.99769152
117peptidyl-arginine N-methylation (GO:0035246)2.97553029
118peptidyl-arginine methylation (GO:0018216)2.97553029
119positive regulation of cell cycle arrest (GO:0071158)2.97415432
120regulation of ligase activity (GO:0051340)2.96776572
1217-methylguanosine mRNA capping (GO:0006370)2.96081119
122mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.94815685
123protoporphyrinogen IX biosynthetic process (GO:0006782)2.93012253
124lipopolysaccharide biosynthetic process (GO:0009103)2.92574370
125chaperone-mediated protein transport (GO:0072321)2.90911913
126antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.90780666
127DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.89662983
128UTP biosynthetic process (GO:0006228)2.89266240
129folic acid-containing compound biosynthetic process (GO:0009396)2.88915136
1307-methylguanosine RNA capping (GO:0009452)2.88014126
131RNA capping (GO:0036260)2.88014126
132L-serine metabolic process (GO:0006563)2.87115552
133protein targeting to mitochondrion (GO:0006626)2.86877065
134transcription from RNA polymerase I promoter (GO:0006360)2.86249954
135GTP biosynthetic process (GO:0006183)2.85833605
136UV protection (GO:0009650)2.83545160
137IMP metabolic process (GO:0046040)2.82870732
138heme metabolic process (GO:0042168)2.82141168
139pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.81338253
140protein complex disassembly (GO:0043241)2.80973395
141establishment of protein localization to mitochondrion (GO:0072655)2.80858709
142termination of RNA polymerase I transcription (GO:0006363)2.80034346
143ATP synthesis coupled proton transport (GO:0015986)2.78320587
144energy coupled proton transport, down electrochemical gradient (GO:0015985)2.78320587
145purine nucleotide salvage (GO:0032261)2.75971756
146protein localization to mitochondrion (GO:0070585)2.75818583
147UTP metabolic process (GO:0046051)2.75712391
148purine deoxyribonucleotide catabolic process (GO:0009155)2.75359289
149viral mRNA export from host cell nucleus (GO:0046784)2.74396631
150nucleotide salvage (GO:0043173)2.74322944
151deoxyribonucleotide metabolic process (GO:0009262)2.74249950
152pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.73829290
153COPI coating of Golgi vesicle (GO:0048205)2.73520382

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.96697414
2* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.22237806
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.14287223
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.71052591
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.58651728
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.35935175
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.34696842
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.25830948
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.23332749
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.10254333
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.00864089
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.75455992
13* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.71085390
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.59544279
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.47613915
16VDR_23849224_ChIP-Seq_CD4+_Human2.34239303
17E2F1_18555785_ChIP-Seq_MESCs_Mouse2.27480388
18XRN2_22483619_ChIP-Seq_HELA_Human2.25504885
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.20054827
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19599325
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.19057356
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.17382654
23DCP1A_22483619_ChIP-Seq_HELA_Human2.17239162
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.09053912
25SRF_21415370_ChIP-Seq_HL-1_Mouse2.07515764
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.05464497
27YY1_21170310_ChIP-Seq_MESCs_Mouse2.03684918
28GABP_19822575_ChIP-Seq_HepG2_Human2.03670098
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.03023255
30THAP11_20581084_ChIP-Seq_MESCs_Mouse2.01139961
31FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.98898957
32* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.96061185
33FOXP3_21729870_ChIP-Seq_TREG_Human1.95280562
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.83629505
35TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.79108428
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.73150781
37* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.70458170
38TTF2_22483619_ChIP-Seq_HELA_Human1.70171951
39PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.68819311
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63140390
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61595995
42MYCN_18555785_ChIP-Seq_MESCs_Mouse1.56925066
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56118986
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52631153
45TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.51929704
46MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.50831906
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.50734088
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.50628927
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.49602475
50ERG_20887958_ChIP-Seq_HPC-7_Mouse1.46355480
51ELF1_20517297_ChIP-Seq_JURKAT_Human1.46030106
52CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.45168708
53FOXM1_23109430_ChIP-Seq_U2OS_Human1.44092808
54* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.41816512
55NCOR1_26117541_ChIP-Seq_K562_Human1.40596803
56ELK1_19687146_ChIP-ChIP_HELA_Human1.37997955
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37083303
58* TET1_21451524_ChIP-Seq_MESCs_Mouse1.32879040
59LXR_22292898_ChIP-Seq_THP-1_Human1.30221922
60CIITA_25753668_ChIP-Seq_RAJI_Human1.29883737
61BCL6_27268052_Chip-Seq_Bcells_Human1.29408828
62P68_20966046_ChIP-Seq_HELA_Human1.26652151
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.25049048
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.24560158
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.24200239
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.23918487
67CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23768772
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.22757659
69* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.21904054
70KDM5A_27292631_Chip-Seq_BREAST_Human1.18850442
71BCOR_27268052_Chip-Seq_Bcells_Human1.18203230
72HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16525586
73YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16362478
74* FOXP1_21924763_ChIP-Seq_HESCs_Human1.16002505
75CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.15219137
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.14487523
77AR_21909140_ChIP-Seq_LNCAP_Human1.12994783
78ELK1_22589737_ChIP-Seq_MCF10A_Human1.11568378
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.11120317
80POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10413519
81SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.10019214
82CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09921590
83CTCF_26484167_Chip-Seq_Bcells_Mouse1.07933750
84KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07702943
85KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06165846
86* TFEB_21752829_ChIP-Seq_HELA_Human1.04293318
87DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04093889
88* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03794331
89DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03169208
90* SPI1_23547873_ChIP-Seq_NB4_Human1.01325974
91PHF8_20622854_ChIP-Seq_HELA_Human1.01057875
92TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00808010
93ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00600208
94E2F1_20622854_ChIP-Seq_HELA_Human0.99371070
95MYC_22102868_ChIP-Seq_BL_Human0.99349298
96LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.98989282
97CTCF_27219007_Chip-Seq_ERYTHROID_Human0.98349711
98LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.98224063
99CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98220009
100* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.97720011
101E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97651421
102CTCF_18555785_ChIP-Seq_MESCs_Mouse0.96863055
103RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.96812565
104VDR_21846776_ChIP-Seq_THP-1_Human0.94216686
105ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93769951
106CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93430392
107SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92096034
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91929727
109GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88570565
110SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.88179348
111NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.88046793
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.88008276
113TBX5_21415370_ChIP-Seq_HL-1_Mouse0.87440451
114KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86136528
115YY1_22570637_ChIP-Seq_MALME-3M_Human0.85530460
116OCT4_18692474_ChIP-Seq_MEFs_Mouse0.85332338
117EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.85092239
118ZNF263_19887448_ChIP-Seq_K562_Human0.84956524
119PADI4_21655091_ChIP-ChIP_MCF-7_Human0.81266576

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.27725784
2MP0004957_abnormal_blastocyst_morpholog3.90795373
3MP0003806_abnormal_nucleotide_metabolis3.47510573
4MP0010094_abnormal_chromosome_stability3.29974101
5MP0003111_abnormal_nucleus_morphology3.27039165
6MP0003077_abnormal_cell_cycle3.18568788
7MP0003186_abnormal_redox_activity3.02749453
8MP0000372_irregular_coat_pigmentation2.84091256
9MP0008057_abnormal_DNA_replication2.79930233
10MP0008058_abnormal_DNA_repair2.71900274
11MP0008007_abnormal_cellular_replicative2.51179003
12MP0002396_abnormal_hematopoietic_system2.49261393
13MP0009278_abnormal_bone_marrow2.42138767
14MP0003646_muscle_fatigue2.18878063
15MP0008932_abnormal_embryonic_tissue2.18508630
16MP0006036_abnormal_mitochondrial_physio2.17080312
17MP0005451_abnormal_body_composition2.13368101
18MP0003786_premature_aging1.97616886
19MP0001853_heart_inflammation1.90453744
20MP0008260_abnormal_autophagy1.86192267
21MP0009379_abnormal_foot_pigmentation1.84050518
22MP0001542_abnormal_bone_strength1.80067549
23MP0009697_abnormal_copulation1.76061683
24MP0001764_abnormal_homeostasis1.74979949
25MP0005171_absent_coat_pigmentation1.73919652
26MP0005397_hematopoietic_system_phenotyp1.66815549
27MP0001545_abnormal_hematopoietic_system1.66815549
28MP0002132_abnormal_respiratory_system1.65410557
29MP0009333_abnormal_splenocyte_physiolog1.65060071
30MP0009840_abnormal_foam_cell1.63223910
31MP0003718_maternal_effect1.59403277
32MP0000358_abnormal_cell_content/1.57337335
33MP0000490_abnormal_crypts_of1.54020628
34MP0006035_abnormal_mitochondrial_morpho1.51336738
35MP0008995_early_reproductive_senescence1.49053133
36MP0001730_embryonic_growth_arrest1.48196174
37MP0000015_abnormal_ear_pigmentation1.45083863
38MP0000350_abnormal_cell_proliferation1.43116710
39MP0006054_spinal_hemorrhage1.38346383
40MP0004147_increased_porphyrin_level1.30938282
41MP0000313_abnormal_cell_death1.30638777
42MP0003123_paternal_imprinting1.28081893
43MP0001661_extended_life_span1.26160026
44MP0002019_abnormal_tumor_incidence1.25472010
45MP0002653_abnormal_ependyma_morphology1.25329314
46MP0001835_abnormal_antigen_presentation1.21394725
47MP0003656_abnormal_erythrocyte_physiolo1.19393541
48MP0009764_decreased_sensitivity_to1.19021766
49MP0005075_abnormal_melanosome_morpholog1.17067838
50MP0005266_abnormal_metabolism1.17003980
51MP0002080_prenatal_lethality1.16965539
52MP0000858_altered_metastatic_potential1.14770760
53MP0004808_abnormal_hematopoietic_stem1.10737872
54MP0003436_decreased_susceptibility_to1.10638535
55MP0000689_abnormal_spleen_morphology1.08725276
56MP0002160_abnormal_reproductive_system1.08311971
57MP0005410_abnormal_fertilization1.08017235
58MP0002722_abnormal_immune_system1.07797549
59MP0000750_abnormal_muscle_regeneration1.06691332
60MP0005058_abnormal_lysosome_morphology1.06403179
61MP0003763_abnormal_thymus_physiology1.06003402
62MP0005671_abnormal_response_to1.05492261
63MP0001697_abnormal_embryo_size1.05370373
64MP0001529_abnormal_vocalization1.04600545
65MP0009785_altered_susceptibility_to1.03195419
66MP0005319_abnormal_enzyme/_coenzyme0.96750510
67MP0004084_abnormal_cardiac_muscle0.96621663
68MP0002398_abnormal_bone_marrow0.94294732
69MP0005000_abnormal_immune_tolerance0.94101667
70MP0002429_abnormal_blood_cell0.93831605
71MP0002736_abnormal_nociception_after0.93682232
72MP0003136_yellow_coat_color0.93466496
73MP0001672_abnormal_embryogenesis/_devel0.93381590
74MP0005380_embryogenesis_phenotype0.93381590
75MP0005084_abnormal_gallbladder_morpholo0.91606645
76MP0000678_abnormal_parathyroid_gland0.91110260
77MP0003724_increased_susceptibility_to0.90444971
78MP0005376_homeostasis/metabolism_phenot0.89761038
79MP0003984_embryonic_growth_retardation0.88717665
80MP0005023_abnormal_wound_healing0.88570132
81MP0001727_abnormal_embryo_implantation0.88041474
82MP0002723_abnormal_immune_serum0.87691961
83MP0010352_gastrointestinal_tract_polyps0.87380471
84MP0005636_abnormal_mineral_homeostasis0.87260042
85MP0001819_abnormal_immune_cell0.86140389
86MP0002148_abnormal_hypersensitivity_rea0.85997186
87MP0002420_abnormal_adaptive_immunity0.85118979
88MP0004133_heterotaxia0.84414943
89MP0002088_abnormal_embryonic_growth/wei0.84333130
90MP0003075_altered_response_to0.84238206
91MP0003221_abnormal_cardiomyocyte_apopto0.83646889
92MP0009763_increased_sensitivity_to0.83407699
93MP0002877_abnormal_melanocyte_morpholog0.83390394
94MP0005025_abnormal_response_to0.83163105
95MP0001905_abnormal_dopamine_level0.82982271
96MP0008469_abnormal_protein_level0.82168975
97MP0005330_cardiomyopathy0.81826924
98MP0000343_altered_response_to0.81417245
99MP0002269_muscular_atrophy0.80553061
100MP0003941_abnormal_skin_development0.80078891
101MP0001873_stomach_inflammation0.79236625
102MP0010307_abnormal_tumor_latency0.79114960
103MP0002210_abnormal_sex_determination0.79062949
104MP0002452_abnormal_antigen_presenting0.79039962
105MP0003566_abnormal_cell_adhesion0.78508840
106MP0003567_abnormal_fetal_cardiomyocyte0.77740896
107MP0001929_abnormal_gametogenesis0.77561240
108MP0005165_increased_susceptibility_to0.77130074
109MP0000598_abnormal_liver_morphology0.76794452
110MP0005332_abnormal_amino_acid0.75841078
111MP0001145_abnormal_male_reproductive0.75813787
112MP0009643_abnormal_urine_homeostasis0.75650682
113MP0000749_muscle_degeneration0.75015236
114MP0009765_abnormal_xenobiotic_induced0.73920263
115MP0003303_peritoneal_inflammation0.73722609
116MP0001881_abnormal_mammary_gland0.73696789
117MP0000716_abnormal_immune_system0.73577872
118MP0005584_abnormal_enzyme/coenzyme_acti0.73266671
119MP0005389_reproductive_system_phenotype0.72280813
120MP0002405_respiratory_system_inflammati0.72207540
121MP0005384_cellular_phenotype0.71447162
122MP0008438_abnormal_cutaneous_collagen0.70765454
123MP0003172_abnormal_lysosome_physiology0.70558431
124MP0010030_abnormal_orbit_morphology0.69201880
125MP0005220_abnormal_exocrine_pancreas0.68876948
126MP0004782_abnormal_surfactant_physiolog0.68115909
127MP0000681_abnormal_thyroid_gland0.67604968
128MP0008775_abnormal_heart_ventricle0.67363563
129MP0000703_abnormal_thymus_morphology0.66922382
130MP0008004_abnormal_stomach_pH0.66570548
131MP0005083_abnormal_biliary_tract0.66484507
132MP0001533_abnormal_skeleton_physiology0.65540692
133MP0001845_abnormal_inflammatory_respons0.63785145
134MP0002419_abnormal_innate_immunity0.63691157
135MP0005464_abnormal_platelet_physiology0.63559309
136MP0000465_gastrointestinal_hemorrhage0.63528826
137MP0000685_abnormal_immune_system0.63124534
138MP0002086_abnormal_extraembryonic_tissu0.62924949
139MP0004233_abnormal_muscle_weight0.62443951
140MP0005501_abnormal_skin_physiology0.61190886

Predicted human phenotypes

RankGene SetZ-score
1Cholecystitis (HP:0001082)5.09363396
2Abnormal gallbladder physiology (HP:0012438)5.09363396
3Abnormal number of erythroid precursors (HP:0012131)4.45445960
4Abnormality of cells of the erythroid lineage (HP:0012130)4.45163846
5Aplastic anemia (HP:0001915)3.98890148
6Hepatic necrosis (HP:0002605)3.89077648
7Hepatocellular necrosis (HP:0001404)3.76290854
8Decreased activity of mitochondrial respiratory chain (HP:0008972)3.71946843
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.71946843
10Reticulocytopenia (HP:0001896)3.64463071
11Birth length less than 3rd percentile (HP:0003561)3.58840597
12Oral leukoplakia (HP:0002745)3.55564464
13Carpal bone hypoplasia (HP:0001498)3.44909519
14Rough bone trabeculation (HP:0100670)3.43101855
15Mitochondrial inheritance (HP:0001427)3.39553812
16Type I transferrin isoform profile (HP:0003642)3.35838390
173-Methylglutaconic aciduria (HP:0003535)3.29085160
18Purpura (HP:0000979)3.27437682
19Prolonged bleeding time (HP:0003010)3.26019183
20Acute necrotizing encephalopathy (HP:0006965)3.25339464
21Increased CSF lactate (HP:0002490)3.22143907
22Abnormality of the anterior horn cell (HP:0006802)3.20469994
23Degeneration of anterior horn cells (HP:0002398)3.20469994
24Increased serum lactate (HP:0002151)3.16834943
25Abnormal mitochondria in muscle tissue (HP:0008316)3.13162276
26Thrombocytosis (HP:0001894)3.12622793
27Cerebral hypomyelination (HP:0006808)3.11681905
28Hypertensive crisis (HP:0100735)3.08921087
29Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.06202460
30Hyperthyroidism (HP:0000836)3.02036837
31Reticulocytosis (HP:0001923)3.00073016
32Macrocytic anemia (HP:0001972)2.91277240
33Breast hypoplasia (HP:0003187)2.89268458
34Acute encephalopathy (HP:0006846)2.84609599
35Increased hepatocellular lipid droplets (HP:0006565)2.82525403
36Multiple enchondromatosis (HP:0005701)2.81849111
37Truncus arteriosus (HP:0001660)2.81518112
38Microretrognathia (HP:0000308)2.80315501
39Upper limb muscle weakness (HP:0003484)2.79247702
40Abnormal platelet function (HP:0011869)2.78088496
41Impaired platelet aggregation (HP:0003540)2.78088496
42Cholelithiasis (HP:0001081)2.74687006
43Hepatosplenomegaly (HP:0001433)2.73972011
44Lipid accumulation in hepatocytes (HP:0006561)2.73388975
45Reduced antithrombin III activity (HP:0001976)2.71713079
46Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.71712282
47Irregular epiphyses (HP:0010582)2.70014159
48Ragged-red muscle fibers (HP:0003200)2.68654260
49Abnormal glycosylation (HP:0012345)2.68451967
50Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.68451967
51Abnormal protein N-linked glycosylation (HP:0012347)2.68451967
52Abnormal protein glycosylation (HP:0012346)2.68451967
53Lactic acidosis (HP:0003128)2.65785245
54Generalized aminoaciduria (HP:0002909)2.58586535
55Increased serum ferritin (HP:0003281)2.57230341
5611 pairs of ribs (HP:0000878)2.57229162
57Abnormality of reticulocytes (HP:0004312)2.56105419
58Increased intramyocellular lipid droplets (HP:0012240)2.55381090
59Pancytopenia (HP:0001876)2.54190127
60Selective tooth agenesis (HP:0001592)2.52254031
61Exertional dyspnea (HP:0002875)2.51317524
62Pallor (HP:0000980)2.51178653
63Abnormal gallbladder morphology (HP:0012437)2.47836666
64Abnormal trabecular bone morphology (HP:0100671)2.46389514
65Exercise intolerance (HP:0003546)2.45395904
66Increased mean platelet volume (HP:0011877)2.40279079
67Respiratory failure (HP:0002878)2.39448046
68Obstructive lung disease (HP:0006536)2.38243771
69Chronic obstructive pulmonary disease (HP:0006510)2.38243771
70Trismus (HP:0000211)2.38146119
71Increased muscle lipid content (HP:0009058)2.38074933
72Secondary amenorrhea (HP:0000869)2.37661312
73CNS demyelination (HP:0007305)2.37459486
74Sparse eyelashes (HP:0000653)2.36195517
75Menorrhagia (HP:0000132)2.32283890
76Vacuolated lymphocytes (HP:0001922)2.31173827
77Abnormal platelet volume (HP:0011876)2.29780237
78Epistaxis (HP:0000421)2.29562426
79Prolonged neonatal jaundice (HP:0006579)2.27106716
80Aplasia/Hypoplasia of the sacrum (HP:0008517)2.26911314
81Abnormality of dicarboxylic acid metabolism (HP:0010995)2.26582626
82Dicarboxylic aciduria (HP:0003215)2.26582626
83Progressive muscle weakness (HP:0003323)2.26062231
84Progressive macrocephaly (HP:0004481)2.25010898
85Poor head control (HP:0002421)2.24116439
86Abnormality of glycolipid metabolism (HP:0010969)2.23351213
87Abnormality of liposaccharide metabolism (HP:0010968)2.23351213
88Abnormality of glycosphingolipid metabolism (HP:0004343)2.23351213
89Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.23246394
90Respiratory difficulties (HP:0002880)2.21256858
91Premature graying of hair (HP:0002216)2.17472464
92Nausea (HP:0002018)2.17377244
93Cerebral palsy (HP:0100021)2.16936819
94Testicular atrophy (HP:0000029)2.16729746
95Renal Fanconi syndrome (HP:0001994)2.16373306
96Megaloblastic anemia (HP:0001889)2.14559085
97Petechiae (HP:0000967)2.14301792
98Dysautonomia (HP:0002459)2.12443275
99Cerebral edema (HP:0002181)2.10542848
100Abnormality of iron homeostasis (HP:0011031)2.10253757
101Premature ovarian failure (HP:0008209)2.09854255
102Abnormality of the heme biosynthetic pathway (HP:0010472)2.05718721
103Beaking of vertebral bodies (HP:0004568)2.05588788
104Nonimmune hydrops fetalis (HP:0001790)2.02671135
105Abnormality of the gallbladder (HP:0005264)2.01974744
106Microvesicular hepatic steatosis (HP:0001414)2.00002988
107Vertebral compression fractures (HP:0002953)1.99900968
108Emotional lability (HP:0000712)1.99644306
109Hypokinesia (HP:0002375)1.98255561
110Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.97286946
111Abnormality of alanine metabolism (HP:0010916)1.97286946
112Hyperalaninemia (HP:0003348)1.97286946
113Redundant skin (HP:0001582)1.95825610
114Paralysis (HP:0003470)1.95607212
115Orthostatic hypotension (HP:0001278)1.95222722
116Abnormality of lateral ventricle (HP:0030047)1.93487166
117Seborrheic dermatitis (HP:0001051)1.93376179
118Progressive microcephaly (HP:0000253)1.92537699
119Hyperbilirubinemia (HP:0002904)1.90727882
120Slender long bone (HP:0003100)1.90289280
121Type 2 muscle fiber atrophy (HP:0003554)1.90060489
122Methylmalonic aciduria (HP:0012120)1.89513773
123Opisthotonus (HP:0002179)1.89249271
124Bone marrow hypocellularity (HP:0005528)1.86705740
125Cleft eyelid (HP:0000625)1.86637536
126Abnormal pupillary function (HP:0007686)1.85646030
127Colon cancer (HP:0003003)1.84529470
128Lethargy (HP:0001254)1.84414378
129Biconcave vertebral bodies (HP:0004586)1.81363729
130Abnormality of glycolysis (HP:0004366)1.80185280
131Increased serum pyruvate (HP:0003542)1.80185280
132Patent foramen ovale (HP:0001655)1.79002389
133Cellular immunodeficiency (HP:0005374)1.78785963
134Muscle fiber atrophy (HP:0100295)1.78500530
135Patellar aplasia (HP:0006443)1.77878503
136IgM deficiency (HP:0002850)1.77816073
137Absent thumb (HP:0009777)1.77789255
138CNS hypomyelination (HP:0003429)1.76956149
139Death in infancy (HP:0001522)1.76603302
140Glossoptosis (HP:0000162)1.76338005
141Abnormal spermatogenesis (HP:0008669)1.75668948
142Abnormality of pyrimidine metabolism (HP:0004353)1.72055579
143Severe visual impairment (HP:0001141)1.70442762
144Abnormality of the umbilical cord (HP:0010881)1.69346333
145Hypoplasia of the capital femoral epiphysis (HP:0003090)1.68738025

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.69532381
2STK164.32779244
3VRK23.99372499
4NME23.62850493
5WEE13.43028497
6EIF2AK13.10138443
7EIF2AK32.77383021
8PIM22.77260016
9BCKDK2.35980165
10TSSK62.12948850
11KDR2.09914528
12TESK22.03527773
13VRK12.03008357
14CDC71.77432420
15TESK11.68410930
16BRSK21.67525152
17PLK41.59315064
18SRPK11.58072660
19MAP4K21.56766525
20RIPK41.55691024
21PDK41.52883621
22PDK31.52883621
23BMX1.52191829
24NEK11.51760307
25TLK11.50409268
26IRAK31.47152066
27DYRK31.40605018
28ERN11.40600819
29EPHA21.39825649
30ACVR1B1.33467936
31NME11.31852908
32NEK21.31747272
33MAP3K111.30558034
34PDK21.24046584
35SMG11.22659831
36MYLK1.22478274
37TGFBR11.22341285
38MST41.22136444
39SCYL21.20651084
40CSNK1G31.18509723
41RPS6KA41.17815647
42PASK1.15914194
43PLK11.14335813
44TTK1.13376318
45ZAK1.13021671
46CDK71.12424940
47BRAF1.11412613
48IRAK41.11314666
49ARAF1.11275025
50NUAK11.08932376
51BRSK11.06051924
52PAK41.02471246
53RPS6KB21.02327272
54ILK0.98898032
55AURKA0.97602751
56MAP3K30.96897934
57TIE10.96844447
58MATK0.96124577
59AURKB0.95470077
60FLT30.95315696
61TRIB30.94403466
62CDK80.90623453
63LRRK20.89472175
64MAPKAPK30.88528142
65ABL20.87267097
66ATR0.86956956
67CLK10.83582426
68CCNB10.83005631
69PIM10.80756344
70BLK0.76833792
71RAF10.76471203
72MAP2K30.76149273
73TBK10.74860249
74ZAP700.74098868
75PKN20.73259982
76CSNK1A1L0.72169056
77CSNK2A10.71688058
78PLK30.71169178
79CSNK1G20.70416441
80PAK10.68799657
81MAP3K80.68774881
82EIF2AK20.67403057
83MAP2K70.67230219
84KIT0.66618577
85CHEK20.65950258
86CSNK1G10.65352290
87PINK10.65034188
88GRK60.63638544
89STK40.62815534
90TEC0.62329148
91STK100.60221724
92CSNK2A20.59833526
93TYK20.59689712
94MUSK0.59338893
95BMPR20.58628435
96CDK140.57517419
97LMTK20.57514901
98GRK50.57424364
99MAP4K10.54257645
100PKN10.52913867
101PRKCI0.51852511
102CDK190.51129685
103IKBKB0.49667883
104AKT30.49614729
105MAP2K20.49453564
106BTK0.49410499
107TAOK20.48317239
108CDK40.48279251
109LIMK10.48141750
110PBK0.47327678
111RPS6KA50.47236392
112TXK0.46847107
113MKNK10.46709965
114MAPKAPK50.45330355
115PRKG20.44521159
116RPS6KA60.44031531
117CDK11A0.43850071
118SYK0.42903358
119ADRBK20.42465303
120SIK30.41497621
121TRIM280.41480415
122STK240.41296266
123DYRK20.40775890
124DAPK30.39939523
125CHEK10.39725275
126MAPK110.39035840
127CDK150.38948879
128STK38L0.38410632
129MAP3K120.37935822
130CDK180.37820845
131JAK30.36310457
132CAMKK20.35444313
133MARK30.35104063
134DAPK10.34826888
135RPS6KC10.34328723
136LYN0.31585720

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.41752197
2DNA replication_Homo sapiens_hsa030304.28337051
3Ribosome_Homo sapiens_hsa030104.11728656
4RNA polymerase_Homo sapiens_hsa030203.26742973
5Mismatch repair_Homo sapiens_hsa034303.17339116
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.73927442
7Pyrimidine metabolism_Homo sapiens_hsa002402.71354336
8Base excision repair_Homo sapiens_hsa034102.62310606
9Protein export_Homo sapiens_hsa030602.34547676
10Spliceosome_Homo sapiens_hsa030402.32414567
11Nucleotide excision repair_Homo sapiens_hsa034202.31792070
12Homologous recombination_Homo sapiens_hsa034402.15709060
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.10766346
14RNA transport_Homo sapiens_hsa030132.05187127
15Oxidative phosphorylation_Homo sapiens_hsa001901.95930464
16Parkinsons disease_Homo sapiens_hsa050121.89356827
17One carbon pool by folate_Homo sapiens_hsa006701.84604293
18Folate biosynthesis_Homo sapiens_hsa007901.82319774
19Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.71600804
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.71243922
21Selenocompound metabolism_Homo sapiens_hsa004501.56764513
22Huntingtons disease_Homo sapiens_hsa050161.49964562
23Cell cycle_Homo sapiens_hsa041101.49806607
24Purine metabolism_Homo sapiens_hsa002301.47795240
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45362509
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38541135
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.33919516
28Pentose phosphate pathway_Homo sapiens_hsa000301.32314665
29Sulfur relay system_Homo sapiens_hsa041221.29417201
30Cysteine and methionine metabolism_Homo sapiens_hsa002701.27162095
31Basal transcription factors_Homo sapiens_hsa030221.25764216
32Drug metabolism - other enzymes_Homo sapiens_hsa009831.24062351
33Fanconi anemia pathway_Homo sapiens_hsa034601.23482154
34Biosynthesis of amino acids_Homo sapiens_hsa012301.20177733
35RNA degradation_Homo sapiens_hsa030181.15747996
36Carbon metabolism_Homo sapiens_hsa012001.15497950
37Steroid biosynthesis_Homo sapiens_hsa001001.13931879
38Vitamin B6 metabolism_Homo sapiens_hsa007501.13378517
39Fructose and mannose metabolism_Homo sapiens_hsa000511.11181805
40Glutathione metabolism_Homo sapiens_hsa004801.10812305
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.10031572
42Galactose metabolism_Homo sapiens_hsa000521.08656768
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.04502820
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01179996
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.98752264
46Non-homologous end-joining_Homo sapiens_hsa034500.98135360
47Alzheimers disease_Homo sapiens_hsa050100.96177353
48p53 signaling pathway_Homo sapiens_hsa041150.94679463
49Primary immunodeficiency_Homo sapiens_hsa053400.94405516
50N-Glycan biosynthesis_Homo sapiens_hsa005100.93874197
51Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.90269966
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.87728556
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87348610
54Collecting duct acid secretion_Homo sapiens_hsa049660.86708214
55Epstein-Barr virus infection_Homo sapiens_hsa051690.85160296
56Shigellosis_Homo sapiens_hsa051310.81224178
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.80794584
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.78907071
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76866645
60Metabolic pathways_Homo sapiens_hsa011000.74342728
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69652338
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69476815
63Regulation of autophagy_Homo sapiens_hsa041400.67578905
64Arginine and proline metabolism_Homo sapiens_hsa003300.66269927
65Legionellosis_Homo sapiens_hsa051340.62966820
66Pyruvate metabolism_Homo sapiens_hsa006200.60833183
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57859433
68Antigen processing and presentation_Homo sapiens_hsa046120.57678363
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.57389652
70Other glycan degradation_Homo sapiens_hsa005110.57081711
71Arachidonic acid metabolism_Homo sapiens_hsa005900.53855543
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51680334
73Fatty acid metabolism_Homo sapiens_hsa012120.50607556
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49968869
75Propanoate metabolism_Homo sapiens_hsa006400.48565531
76Rheumatoid arthritis_Homo sapiens_hsa053230.45853281
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43041912
78Peroxisome_Homo sapiens_hsa041460.42380904
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42358530
80Synaptic vesicle cycle_Homo sapiens_hsa047210.41985033
81Herpes simplex infection_Homo sapiens_hsa051680.41575856
82Alcoholism_Homo sapiens_hsa050340.40605120
83Systemic lupus erythematosus_Homo sapiens_hsa053220.38846392
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37413634
85mRNA surveillance pathway_Homo sapiens_hsa030150.36603654
86Cardiac muscle contraction_Homo sapiens_hsa042600.34325567
87Phenylalanine metabolism_Homo sapiens_hsa003600.33058113
88Fatty acid degradation_Homo sapiens_hsa000710.32360114
89Caffeine metabolism_Homo sapiens_hsa002320.32017261
90Renin-angiotensin system_Homo sapiens_hsa046140.31932276
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.31610275
92Vitamin digestion and absorption_Homo sapiens_hsa049770.30937975
93Salmonella infection_Homo sapiens_hsa051320.29251826
94Viral carcinogenesis_Homo sapiens_hsa052030.29107838
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29046663
96Hematopoietic cell lineage_Homo sapiens_hsa046400.28901119
97Fatty acid elongation_Homo sapiens_hsa000620.26722453
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.26558035
99Lysosome_Homo sapiens_hsa041420.25557002
100Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.25132569
101Glycosaminoglycan degradation_Homo sapiens_hsa005310.24465050
102Bladder cancer_Homo sapiens_hsa052190.23817057
103Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.23708871
104Sulfur metabolism_Homo sapiens_hsa009200.23672032
105Tyrosine metabolism_Homo sapiens_hsa003500.23308904
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.22802224
107Vibrio cholerae infection_Homo sapiens_hsa051100.22312107
108Apoptosis_Homo sapiens_hsa042100.22292253
109beta-Alanine metabolism_Homo sapiens_hsa004100.21316431
110Maturity onset diabetes of the young_Homo sapiens_hsa049500.20998099
111Thyroid cancer_Homo sapiens_hsa052160.20211978
112HTLV-I infection_Homo sapiens_hsa051660.19147036
113Asthma_Homo sapiens_hsa053100.18464992
114RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.18085323
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.17314383
116Chemical carcinogenesis_Homo sapiens_hsa052040.17245632
117Linoleic acid metabolism_Homo sapiens_hsa005910.16197555
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.15388454

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