YIPF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)7.92600395
2Golgi transport vesicle coating (GO:0048200)7.92600395
3signal peptide processing (GO:0006465)7.35400809
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)6.48692177
5protein maturation by protein folding (GO:0022417)5.87174476
6protein retention in ER lumen (GO:0006621)5.83386957
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.52832913
8protein targeting to ER (GO:0045047)5.44536843
9cotranslational protein targeting to membrane (GO:0006613)5.44482665
10endocrine pancreas development (GO:0031018)5.35379355
11COPII vesicle coating (GO:0048208)5.22450397
12establishment of protein localization to endoplasmic reticulum (GO:0072599)5.20005248
13protein localization to endoplasmic reticulum (GO:0070972)5.14990116
14maturation of SSU-rRNA (GO:0030490)4.95036802
15GDP-mannose metabolic process (GO:0019673)4.91653442
16exocrine pancreas development (GO:0031017)4.91492318
17activation of signaling protein activity involved in unfolded protein response (GO:0006987)4.76777918
18glandular epithelial cell differentiation (GO:0002067)4.76554872
19retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)4.64537001
20positive regulation of nuclease activity (GO:0032075)4.54503664
21peptide hormone processing (GO:0016486)4.47717939
22ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)4.44985589
23sequestering of metal ion (GO:0051238)4.42054313
24regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.39377989
25chaperone-mediated protein transport (GO:0072321)4.30577687
26negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.18961984
27L-phenylalanine metabolic process (GO:0006558)4.18229840
28erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.18229840
29regulation of nuclease activity (GO:0032069)4.17041943
30mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.09099669
31endoplasmic reticulum unfolded protein response (GO:0030968)4.05464734
32protein complex disassembly (GO:0043241)4.01800209
33viral transcription (GO:0019083)4.00825473
34erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.97432386
35L-phenylalanine catabolic process (GO:0006559)3.97432386
36protein N-linked glycosylation via asparagine (GO:0018279)3.95011908
37cellular response to unfolded protein (GO:0034620)3.93362232
38ATP synthesis coupled proton transport (GO:0015986)3.89763725
39energy coupled proton transport, down electrochemical gradient (GO:0015985)3.89763725
40ER overload response (GO:0006983)3.89483081
41peptidyl-asparagine modification (GO:0018196)3.88725525
42translational termination (GO:0006415)3.88013495
43cellular response to topologically incorrect protein (GO:0035967)3.87141265
44regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.86157970
45ER-nucleus signaling pathway (GO:0006984)3.78507184
46ribosomal large subunit biogenesis (GO:0042273)3.74205620
47macromolecular complex disassembly (GO:0032984)3.72288032
48protein targeting to membrane (GO:0006612)3.69335485
49positive regulation of insulin secretion (GO:0032024)3.64558575
50protein N-linked glycosylation (GO:0006487)3.60379723
51ribosomal small subunit assembly (GO:0000028)3.58791590
52ribonucleoprotein complex biogenesis (GO:0022613)3.55823790
53mitotic nuclear envelope reassembly (GO:0007084)3.53141405
54nuclear envelope reassembly (GO:0031468)3.53141405
55establishment of protein localization to mitochondrial membrane (GO:0090151)3.51537423
56deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.51390174
57regulation of glucokinase activity (GO:0033131)3.50097640
58regulation of hexokinase activity (GO:1903299)3.50097640
59regulation of type B pancreatic cell apoptotic process (GO:2000674)3.45616375
60type B pancreatic cell development (GO:0003323)3.45156812
61respiratory electron transport chain (GO:0022904)3.43993363
62response to endoplasmic reticulum stress (GO:0034976)3.42955404
63mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.42601320
64electron transport chain (GO:0022900)3.40703643
65nucleoside diphosphate catabolic process (GO:0009134)3.39197349
66pteridine-containing compound biosynthetic process (GO:0042559)3.35625651
67regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.34024216
68glucosamine-containing compound catabolic process (GO:1901072)3.28815432
69response to unfolded protein (GO:0006986)3.28467155
70translational elongation (GO:0006414)3.28226774
71fucose metabolic process (GO:0006004)3.28141559
72guanosine-containing compound biosynthetic process (GO:1901070)3.26989562
73protein targeting to mitochondrion (GO:0006626)3.26601208
74response to topologically incorrect protein (GO:0035966)3.24040869
75protein autoprocessing (GO:0016540)3.21767807
76cellular component biogenesis (GO:0044085)3.19600759
77UDP-N-acetylglucosamine metabolic process (GO:0006047)3.15946004
78viral life cycle (GO:0019058)3.15640320
79pattern specification involved in kidney development (GO:0061004)3.14971673
80pseudouridine synthesis (GO:0001522)3.13328051
81glandular epithelial cell development (GO:0002068)3.12584911
82nucleotide-sugar metabolic process (GO:0009225)3.12247405
83translation (GO:0006412)3.11253809
84vesicle coating (GO:0006901)3.10955658
85pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.07154873
86DNA deamination (GO:0045006)3.06994438
87establishment of protein localization to mitochondrion (GO:0072655)3.05870989
88regulation of apoptotic process involved in morphogenesis (GO:1902337)3.04924083
89ER to Golgi vesicle-mediated transport (GO:0006888)3.04458627
90cell redox homeostasis (GO:0045454)3.01859555
91intra-Golgi vesicle-mediated transport (GO:0006891)3.00579432
92nucleotide transmembrane transport (GO:1901679)2.98158581
934-hydroxyproline metabolic process (GO:0019471)2.97004071
94GTP biosynthetic process (GO:0006183)2.96888823
95positive regulation of peptide hormone secretion (GO:0090277)2.95207292
96ncRNA 3-end processing (GO:0043628)2.95195517
97intestinal cholesterol absorption (GO:0030299)2.94505927
98termination of RNA polymerase III transcription (GO:0006386)2.92367890
99transcription elongation from RNA polymerase III promoter (GO:0006385)2.92367890
100UV protection (GO:0009650)2.92125537
101GMP metabolic process (GO:0046037)2.90863459
102proline metabolic process (GO:0006560)2.88727579
103ribosomal small subunit biogenesis (GO:0042274)2.88424664
104proline biosynthetic process (GO:0006561)2.88357062
105fucosylation (GO:0036065)2.87393794
106regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.86716257
107cellular protein complex disassembly (GO:0043624)2.86711326
108regulation of insulin secretion (GO:0050796)2.85355075
109dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.84819458
110nuclear-transcribed mRNA catabolic process (GO:0000956)2.82644944
111positive regulation of peptide secretion (GO:0002793)2.82641949
112pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.82510230
113mitochondrial respiratory chain complex assembly (GO:0033108)2.81970060
114mitochondrial respiratory chain complex I assembly (GO:0032981)2.81964952
115NADH dehydrogenase complex assembly (GO:0010257)2.81964952
116mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.81964952
117regulation of translational fidelity (GO:0006450)2.78070065
118nucleotide-sugar biosynthetic process (GO:0009226)2.77843398
119negative regulation of glycoprotein biosynthetic process (GO:0010561)2.76981192
120peptide metabolic process (GO:0006518)2.75581761
121protein insertion into membrane (GO:0051205)2.75139793
122establishment of protein localization to membrane (GO:0090150)2.74415139
123CTP biosynthetic process (GO:0006241)2.73515332
124CTP metabolic process (GO:0046036)2.73515332
125protein localization to mitochondrion (GO:0070585)2.71976724
126regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.70580583
127mRNA catabolic process (GO:0006402)2.70443685
128regulation of translational termination (GO:0006449)2.69594495
129UTP biosynthetic process (GO:0006228)2.69557108
130regulation of peptide hormone secretion (GO:0090276)2.69325079
131insulin secretion (GO:0030073)2.68969829
132formation of translation preinitiation complex (GO:0001731)2.68830166
133pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.68474376
134toxin metabolic process (GO:0009404)2.68289380
135planar cell polarity pathway involved in neural tube closure (GO:0090179)2.67805704
136endosome to melanosome transport (GO:0035646)2.66152545
137endosome to pigment granule transport (GO:0043485)2.66152545
138oxaloacetate metabolic process (GO:0006107)2.64646630
139pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.63866931
140adhesion of symbiont to host (GO:0044406)2.63600171
141zinc ion transport (GO:0006829)2.63374241
142regulation of peptide secretion (GO:0002791)2.63029102
143heterochromatin organization (GO:0070828)2.62253996
144adhesion of symbiont to host cell (GO:0044650)2.62230873
145virion attachment to host cell (GO:0019062)2.62230873
146pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.61926536
147translational initiation (GO:0006413)2.60432278
148tooth mineralization (GO:0034505)2.60143107
149purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.59847590
150purine nucleoside triphosphate biosynthetic process (GO:0009145)2.59517184
151protein targeting (GO:0006605)2.57748130
152L-alpha-amino acid transmembrane transport (GO:1902475)2.56595791
153nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.56529114
154regulation of mitochondrial translation (GO:0070129)2.55931276
155UTP metabolic process (GO:0046051)2.55420940
156protein complex biogenesis (GO:0070271)2.54159445
157ribonucleoside triphosphate biosynthetic process (GO:0009201)2.53691716
158pyrimidine nucleotide catabolic process (GO:0006244)2.53435569
159nucleobase-containing small molecule interconversion (GO:0015949)2.53148648
160viral protein processing (GO:0019082)2.51293647
161regulation of mammary gland epithelial cell proliferation (GO:0033599)2.50612777
162establishment of apical/basal cell polarity (GO:0035089)2.46974091
163endothelial cell chemotaxis (GO:0035767)2.46826833
164RNA catabolic process (GO:0006401)2.45804042
165rRNA processing (GO:0006364)2.44735153
166base-excision repair, AP site formation (GO:0006285)2.44605682
167negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.42697001
168ATP biosynthetic process (GO:0006754)2.40040841

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.34256127
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.92505156
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.90586275
4PDX1_19855005_ChIP-ChIP_MIN6_Mouse3.76840368
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.73101747
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.72015458
7ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.49551719
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.44109008
9CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.33271167
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.91142806
11RXR_22158963_ChIP-Seq_LIVER_Mouse2.86395158
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.85655775
13STAT6_21828071_ChIP-Seq_BEAS2B_Human2.73573842
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.66641767
15DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.58423841
16DCP1A_22483619_ChIP-Seq_HELA_Human2.54580582
17* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.51943193
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.48449419
19RARG_19884340_ChIP-ChIP_MEFs_Mouse2.44507055
20PPARA_22158963_ChIP-Seq_LIVER_Mouse2.44255707
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.36162903
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.30651469
23CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.30617887
24MYC_18555785_ChIP-Seq_MESCs_Mouse2.26554520
25EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.10699150
26CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.05067224
27* RACK7_27058665_Chip-Seq_MCF-7_Human2.02612245
28VDR_21846776_ChIP-Seq_THP-1_Human1.96945290
29FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.95259869
30ELK3_25401928_ChIP-Seq_HUVEC_Human1.89161100
31* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.86714093
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.82880356
33* GABP_19822575_ChIP-Seq_HepG2_Human1.81927015
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81060442
35ERG_20887958_ChIP-Seq_HPC-7_Mouse1.73962047
36LXR_22158963_ChIP-Seq_LIVER_Mouse1.72278225
37VDR_23849224_ChIP-Seq_CD4+_Human1.70848939
38ZFX_18555785_ChIP-Seq_MESCs_Mouse1.67188634
39EGR1_23403033_ChIP-Seq_LIVER_Mouse1.66398683
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.65650791
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.64802978
42P68_20966046_ChIP-Seq_HELA_Human1.59661320
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.59448152
44HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.58839578
45SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.57901150
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.55758336
47XRN2_22483619_ChIP-Seq_HELA_Human1.55443890
48THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.54643093
49ELK1_22589737_ChIP-Seq_MCF10A_Human1.54225732
50* FOXP3_21729870_ChIP-Seq_TREG_Human1.53949151
51* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52584217
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.52440558
53SA1_27219007_Chip-Seq_ERYTHROID_Human1.49152258
54UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.48499034
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.45080166
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.43801775
57ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.42158162
58MYC_19030024_ChIP-ChIP_MESCs_Mouse1.41876275
59SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.37642586
60BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.37584267
61ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36556010
62* TTF2_22483619_ChIP-Seq_HELA_Human1.36064017
63GATA1_22025678_ChIP-Seq_K562_Human1.34667809
64* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.33971043
65ELF1_20517297_ChIP-Seq_JURKAT_Human1.30229820
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28224237
67KLF4_18555785_ChIP-Seq_MESCs_Mouse1.27608322
68CTCF_27219007_Chip-Seq_Bcells_Human1.26440291
69NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.25143608
70SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.24474521
71SOX2_27498859_Chip-Seq_STOMACH_Mouse1.23340390
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.22156718
73CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.22122023
74NELFA_20434984_ChIP-Seq_ESCs_Mouse1.21608335
75KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.21552424
76CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.21226796
77ATF3_27146783_Chip-Seq_COLON_Human1.21132955
78MYC_19079543_ChIP-ChIP_MESCs_Mouse1.20995120
79KDM5A_27292631_Chip-Seq_BREAST_Human1.20830486
80CTCF_27219007_Chip-Seq_ERYTHROID_Human1.20828090
81CTCF_18555785_ChIP-Seq_MESCs_Mouse1.20791352
82POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20520501
83TRIM28_21343339_ChIP-Seq_HEK293_Human1.20253373
84CTCF_26484167_Chip-Seq_Bcells_Mouse1.19435219
85CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19080900
86BCL6_27268052_Chip-Seq_Bcells_Human1.18518081
87TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18194930
88KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.18158781
89PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.17930274
90SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.17559818
91SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.17532528
92YY1_21170310_ChIP-Seq_MESCs_Mouse1.16801595
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.16288091
94HIF1A_21447827_ChIP-Seq_MCF-7_Human1.14909016
95ESR2_21235772_ChIP-Seq_MCF-7_Human1.14604488
96ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.14385281
97FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.13881137
98E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.13407735
99MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.13120609
100TP53_22127205_ChIP-Seq_IMR90_Human1.11868827
101ERG_20517297_ChIP-Seq_VCAP_Human1.11666787
102YY1_22570637_ChIP-Seq_MALME-3M_Human1.11008519
103BCOR_27268052_Chip-Seq_Bcells_Human1.10643144
104SMC4_20622854_ChIP-Seq_HELA_Human1.10093222
105OCT4_18692474_ChIP-Seq_MEFs_Mouse1.09703189
106SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.08934170
107ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.08388324
108CREB1_26743006_Chip-Seq_LNCaP_Human1.08012267
109ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.08001241
110CTCF_20526341_ChIP-Seq_ESCs_Human1.07843381
111TET1_21451524_ChIP-Seq_MESCs_Mouse1.06840530
112KDM2B_26808549_Chip-Seq_SUP-B15_Human1.05597396
113NANOG_18555785_ChIP-Seq_MESCs_Mouse1.05442924
114TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05268999
115KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04141185
116RARA_24833708_ChIP-Seq_LIVER_Mouse1.03412121
117PHF8_20622854_ChIP-Seq_HELA_Human1.03174046
118* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.02067440
119E2F1_20622854_ChIP-Seq_HELA_Human1.01684155
120KDM2B_26808549_Chip-Seq_K562_Human1.01608899
121LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.01362775
122ESR1_21235772_ChIP-Seq_MCF-7_Human1.00957479
123SA1_27219007_Chip-Seq_Bcells_Human1.00901500
124ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00782136
125RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99574051
126MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.99425584
127HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98605235
128PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.98603162
129ZNF263_19887448_ChIP-Seq_K562_Human0.97131390
130SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96168045
131ELK1_19687146_ChIP-ChIP_HELA_Human0.95876943
132ZNF274_21170338_ChIP-Seq_K562_Hela0.95410164
133DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95372913
134GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94845703
135AR_20517297_ChIP-Seq_VCAP_Human0.93215251
136* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.93063394
137TBX5_21415370_ChIP-Seq_HL-1_Mouse0.91256076
138SOX17_20123909_ChIP-Seq_XEN_Mouse0.90696820
139STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.89327477
140MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.88337275
141FOXP1_21924763_ChIP-Seq_HESCs_Human0.88211888
142TFEB_21752829_ChIP-Seq_HELA_Human0.88170342
143* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.87656606
144STAT1_20625510_ChIP-Seq_HELA_Human0.87330118
145LXR_22292898_ChIP-Seq_THP-1_Human0.84973297
146CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84855979
147PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.84509638
148PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.83733537
149RARB_24833708_ChIP-Seq_LIVER_Mouse0.83662153
150MYCN_18555785_ChIP-Seq_MESCs_Mouse0.82840123
151RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.81409512
152TP53_22573176_ChIP-Seq_HFKS_Human0.80446523
153BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.79209496

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.09050600
2MP0005220_abnormal_exocrine_pancreas4.07778672
3MP0002139_abnormal_hepatobiliary_system4.00838137
4MP0003195_calcinosis3.92368734
5MP0001944_abnormal_pancreas_morphology3.71626467
6MP0002693_abnormal_pancreas_physiology3.68284107
7MP0010030_abnormal_orbit_morphology3.46731530
8MP0008438_abnormal_cutaneous_collagen3.24276387
9MP0003183_abnormal_peptide_metabolism3.12821887
10MP0004043_abnormal_pH_regulation3.11762100
11MP0003705_abnormal_hypodermis_morpholog3.10261591
12MP0010386_abnormal_urinary_bladder3.04190303
13MP0005365_abnormal_bile_salt3.04120256
14MP0002877_abnormal_melanocyte_morpholog3.03863355
15MP0000678_abnormal_parathyroid_gland2.94715066
16MP0004858_abnormal_nervous_system2.93507632
17MP0005379_endocrine/exocrine_gland_phen2.87772833
18MP0000013_abnormal_adipose_tissue2.66329493
19MP0002909_abnormal_adrenal_gland2.58841794
20MP0003123_paternal_imprinting2.52546649
21MP0003724_increased_susceptibility_to2.48080694
22MP0001666_abnormal_nutrient_absorption2.42732534
23MP0003283_abnormal_digestive_organ2.30614444
24MP0005501_abnormal_skin_physiology2.25460649
25MP0009840_abnormal_foam_cell2.25035311
26MP0006072_abnormal_retinal_apoptosis2.12939455
27MP0004264_abnormal_extraembryonic_tissu2.12368695
28MP0008875_abnormal_xenobiotic_pharmacok2.07412626
29MP0000613_abnormal_salivary_gland2.04995136
30MP0003868_abnormal_feces_composition2.02289423
31MP0002638_abnormal_pupillary_reflex2.01919668
32MP0002078_abnormal_glucose_homeostasis2.01332125
33MP0005636_abnormal_mineral_homeostasis1.99624984
34MP0002837_dystrophic_cardiac_calcinosis1.99181843
35MP0005083_abnormal_biliary_tract1.97632452
36MP0005085_abnormal_gallbladder_physiolo1.95774825
37MP0004272_abnormal_basement_membrane1.90170515
38MP0009384_cardiac_valve_regurgitation1.85958153
39MP0001765_abnormal_ion_homeostasis1.82453230
40MP0002254_reproductive_system_inflammat1.78250359
41MP0009643_abnormal_urine_homeostasis1.78029678
42MP0005084_abnormal_gallbladder_morpholo1.70789795
43MP0005503_abnormal_tendon_morphology1.68819519
44MP0003693_abnormal_embryo_hatching1.66868304
45MP0002249_abnormal_larynx_morphology1.65533228
46MP0003959_abnormal_lean_body1.61310324
47MP0009780_abnormal_chondrocyte_physiolo1.57895868
48MP0002060_abnormal_skin_morphology1.56311835
49MP0003942_abnormal_urinary_system1.52817572
50MP0003279_aneurysm1.52194306
51MP0003566_abnormal_cell_adhesion1.49202598
52MP0005257_abnormal_intraocular_pressure1.47798155
53MP0003315_abnormal_perineum_morphology1.46869105
54MP0003122_maternal_imprinting1.46700812
55MP0001849_ear_inflammation1.41864364
56MP0005360_urolithiasis1.41514013
57MP0005275_abnormal_skin_tensile1.41430558
58MP0003866_abnormal_defecation1.39840291
59MP0003453_abnormal_keratinocyte_physiol1.39369361
60MP0002163_abnormal_gland_morphology1.38775188
61MP0003252_abnormal_bile_duct1.38158511
62MP0001542_abnormal_bone_strength1.38103429
63MP0000003_abnormal_adipose_tissue1.37791547
64MP0001756_abnormal_urination1.37758022
65MP0005332_abnormal_amino_acid1.34535186
66MP0002089_abnormal_postnatal_growth/wei1.32399124
67MP0010234_abnormal_vibrissa_follicle1.31542885
68MP0005508_abnormal_skeleton_morphology1.30336169
69MP0000049_abnormal_middle_ear1.29753977
70MP0003953_abnormal_hormone_level1.28689858
71MP0005451_abnormal_body_composition1.28604741
72MP0002876_abnormal_thyroid_physiology1.27667208
73MP0001881_abnormal_mammary_gland1.26288206
74MP0005623_abnormal_meninges_morphology1.25724180
75MP0005645_abnormal_hypothalamus_physiol1.16639932
76MP0000762_abnormal_tongue_morphology1.13807435
77MP0002653_abnormal_ependyma_morphology1.13752019
78MP0003186_abnormal_redox_activity1.13715504
79MP0006276_abnormal_autonomic_nervous1.12717739
80MP0010771_integument_phenotype1.12717430
81MP0002160_abnormal_reproductive_system1.12682192
82MP0010329_abnormal_lipoprotein_level1.12261474
83MP0001986_abnormal_taste_sensitivity1.11602557
84MP0000631_abnormal_neuroendocrine_gland1.10826986
85MP0002138_abnormal_hepatobiliary_system1.08215993
86MP0008007_abnormal_cellular_replicative1.07354414
87MP0002295_abnormal_pulmonary_circulatio1.06253949
88MP0005646_abnormal_pituitary_gland1.05386350
89MP0006036_abnormal_mitochondrial_physio1.05000709
90MP0006054_spinal_hemorrhage1.04882079
91MP0002118_abnormal_lipid_homeostasis1.03106241
92MP0000579_abnormal_nail_morphology1.02709492
93MP0005023_abnormal_wound_healing1.01812260
94MP0002928_abnormal_bile_duct1.01619665
95MP0004782_abnormal_surfactant_physiolog1.01084691
96MP0003172_abnormal_lysosome_physiology1.00970524
97MP0009053_abnormal_anal_canal1.00849154
98MP0001764_abnormal_homeostasis1.00472811
99MP0009250_abnormal_appendicular_skeleto0.99961617
100MP0000467_abnormal_esophagus_morphology0.99817702
101MP0000537_abnormal_urethra_morphology0.99700040
102MP0008932_abnormal_embryonic_tissue0.99552023
103MP0000462_abnormal_digestive_system0.99519471
104MP0004957_abnormal_blastocyst_morpholog0.97611248
105MP0000750_abnormal_muscle_regeneration0.93929571
106MP0001270_distended_abdomen0.92338755
107MP0002234_abnormal_pharynx_morphology0.90532117
108MP0001216_abnormal_epidermal_layer0.90530160
109MP0004019_abnormal_vitamin_homeostasis0.90228638
110MP0008260_abnormal_autophagy0.89363311
111MP0000230_abnormal_systemic_arterial0.88758767
112MP0003329_amyloid_beta_deposits0.88366439
113MP0003786_premature_aging0.88178602
114MP0009642_abnormal_blood_homeostasis0.87793038
115MP0005319_abnormal_enzyme/_coenzyme0.86704613
116MP0003300_gastrointestinal_ulcer0.85932695
117MP0005310_abnormal_salivary_gland0.85025061
118MP0003806_abnormal_nucleotide_metabolis0.84992961
119MP0001905_abnormal_dopamine_level0.84025535
120MP0005409_darkened_coat_color0.79816850
121MP0009931_abnormal_skin_appearance0.79674553
122MP0000609_abnormal_liver_physiology0.79509858
123MP0003119_abnormal_digestive_system0.79235867
124MP0001664_abnormal_digestion0.77968229
125MP0003879_abnormal_hair_cell0.77751049
126MP0005448_abnormal_energy_balance0.77541785
127MP0001958_emphysema0.77035927
128MP0002896_abnormal_bone_mineralization0.75937136
129MP0003385_abnormal_body_wall0.75549648
130MP0000538_abnormal_urinary_bladder0.75158254
131MP0005408_hypopigmentation0.75102640
132MP0000534_abnormal_ureter_morphology0.74586377
133MP0001502_abnormal_circadian_rhythm0.74288536
134MP0001188_hyperpigmentation0.73963909
135MP0001348_abnormal_lacrimal_gland0.73465057
136MP0002932_abnormal_joint_morphology0.73098048
137MP0002796_impaired_skin_barrier0.72814037
138MP0000681_abnormal_thyroid_gland0.72079533
139MP0002111_abnormal_tail_morphology0.70579672
140MP0000639_abnormal_adrenal_gland0.69359193
141MP0002092_abnormal_eye_morphology0.68793503
142MP0003941_abnormal_skin_development0.67179598
143MP0005375_adipose_tissue_phenotype0.66428318
144MP0000566_synostosis0.65821075
145MP0005535_abnormal_body_temperature0.65033775
146MP0006292_abnormal_olfactory_placode0.64801355
147MP0005058_abnormal_lysosome_morphology0.64776301
148MP0002177_abnormal_outer_ear0.63872853
149MP0004233_abnormal_muscle_weight0.63255099
150MP0005381_digestive/alimentary_phenotyp0.62765362
151MP0005193_abnormal_anterior_eye0.62498837
152MP0002116_abnormal_craniofacial_bone0.62426883
153MP0001727_abnormal_embryo_implantation0.61738590
154MP0000490_abnormal_crypts_of0.61638602
155MP0002085_abnormal_embryonic_tissue0.61275551
156MP0002697_abnormal_eye_size0.61030119
157MP0005165_increased_susceptibility_to0.60759958
158MP0004381_abnormal_hair_follicle0.59811646
159MP0005174_abnormal_tail_pigmentation0.59484745
160MP0004133_heterotaxia0.58793441
161MP0000358_abnormal_cell_content/0.57346413
162MP0002751_abnormal_autonomic_nervous0.55608732
163MP0002098_abnormal_vibrissa_morphology0.54739469
164MP0000465_gastrointestinal_hemorrhage0.52960611
165MP0009672_abnormal_birth_weight0.52855882
166MP0005584_abnormal_enzyme/coenzyme_acti0.52727718
167MP0005075_abnormal_melanosome_morpholog0.51147550
168MP0005334_abnormal_fat_pad0.49609820
169MP0005595_abnormal_vascular_smooth0.48979011

Predicted human phenotypes

RankGene SetZ-score
1Hyperinsulinemic hypoglycemia (HP:0000825)5.42299411
2Abnormality of aromatic amino acid family metabolism (HP:0004338)5.10783600
3Hypoglycemic coma (HP:0001325)4.89168576
4Hypoglycemic seizures (HP:0002173)4.89121307
5Symptomatic seizures (HP:0011145)4.40856150
6Elevated circulating parathyroid hormone (PTH) level (HP:0003165)4.25969852
7Ketoacidosis (HP:0001993)4.13470259
8Abnormality of cells of the erythroid lineage (HP:0012130)4.05042763
9Abnormal number of erythroid precursors (HP:0012131)3.95642415
10Abnormality of the intrinsic pathway (HP:0010989)3.95205304
11Hyperglycemia (HP:0003074)3.69581216
12Late onset (HP:0003584)3.61813590
13Premature rupture of membranes (HP:0001788)3.61515995
14Type I transferrin isoform profile (HP:0003642)3.46992032
15Generalized aminoaciduria (HP:0002909)3.40616752
16Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.37281594
17Abnormal protein N-linked glycosylation (HP:0012347)3.37281594
18Abnormal protein glycosylation (HP:0012346)3.37281594
19Abnormal glycosylation (HP:0012345)3.37281594
20Hyperthyroidism (HP:0000836)3.35705117
21Insulin-resistant diabetes mellitus (HP:0000831)3.34514428
22Abnormal pupillary function (HP:0007686)3.09575224
23Hepatic necrosis (HP:0002605)3.09195844
24Protrusio acetabuli (HP:0003179)3.07535902
25Abnormality of calcium-phosphate metabolism (HP:0100530)3.07082333
26Ketosis (HP:0001946)2.98462321
27Hyperphosphaturia (HP:0003109)2.98349201
28Conjugated hyperbilirubinemia (HP:0002908)2.97612943
29Abnormal mitochondria in muscle tissue (HP:0008316)2.95305785
30Cervical subluxation (HP:0003308)2.93299451
31Acute necrotizing encephalopathy (HP:0006965)2.91636929
32Acute encephalopathy (HP:0006846)2.89815426
33Vertebral compression fractures (HP:0002953)2.85711344
34Abnormality of endocrine pancreas physiology (HP:0012093)2.77291820
35Abnormality of the pancreatic islet cells (HP:0006476)2.77291820
36Microretrognathia (HP:0000308)2.74403591
37Abnormal pancreas size (HP:0012094)2.74225054
38Abnormality of the common coagulation pathway (HP:0010990)2.73307438
39Insulin resistance (HP:0000855)2.67862997
40Aplasia/hypoplasia of the uterus (HP:0008684)2.67557682
41Dysostosis multiplex (HP:0000943)2.67039216
42Decreased circulating renin level (HP:0003351)2.66608963
43Abnormality of urine glucose concentration (HP:0011016)2.66417494
44Glycosuria (HP:0003076)2.66417494
45Abnormal hemoglobin (HP:0011902)2.64766508
46Hepatocellular necrosis (HP:0001404)2.62699897
47Urinary glycosaminoglycan excretion (HP:0003541)2.59052138
48Mucopolysacchariduria (HP:0008155)2.59052138
49Achilles tendon contracture (HP:0001771)2.57478493
50Vacuolated lymphocytes (HP:0001922)2.55990547
51Mitochondrial inheritance (HP:0001427)2.53361812
52Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.53296527
53Large for gestational age (HP:0001520)2.49730372
54Fragile skin (HP:0001030)2.46731668
55Atrophic scars (HP:0001075)2.45623045
56Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.45205545
57Prolonged partial thromboplastin time (HP:0003645)2.43429836
58Agitation (HP:0000713)2.42306890
59Testicular atrophy (HP:0000029)2.41384124
60Redundant skin (HP:0001582)2.40035698
61Abnormal urine phosphate concentration (HP:0012599)2.39099058
62Hyperphosphatemia (HP:0002905)2.38358495
63Hyperacusis (HP:0010780)2.38269556
64Truncus arteriosus (HP:0001660)2.36916865
65Abnormality of the Achilles tendon (HP:0005109)2.33553812
66Aplasia/Hypoplasia of the sacrum (HP:0008517)2.33475192
67Progressive macrocephaly (HP:0004481)2.32170603
68Trismus (HP:0000211)2.31698151
69Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.28162991
70Decreased activity of mitochondrial respiratory chain (HP:0008972)2.28162991
71Increased intramyocellular lipid droplets (HP:0012240)2.27367493
723-Methylglutaconic aciduria (HP:0003535)2.26473637
73Joint stiffness (HP:0001387)2.23721066
74J-shaped sella turcica (HP:0002680)2.23089036
75Gout (HP:0001997)2.22771358
76Pallor (HP:0000980)2.22567042
77Hypokinesia (HP:0002375)2.20634647
78Bladder diverticulum (HP:0000015)2.20160649
79Generalized hyperpigmentation (HP:0007440)2.19759101
80Abnormality of monocarboxylic acid metabolism (HP:0010996)2.19494237
81Abnormality of polysaccharide metabolism (HP:0011012)2.19393934
82Abnormality of glycosaminoglycan metabolism (HP:0004371)2.19393934
83Abnormality of mucopolysaccharide metabolism (HP:0011020)2.19393934
84Increased muscle lipid content (HP:0009058)2.18720251
85Cortical visual impairment (HP:0100704)2.18668814
86Aplastic anemia (HP:0001915)2.17617987
87Progressive neurologic deterioration (HP:0002344)2.15685502
88Abnormality of dentin (HP:0010299)2.14922371
89Atelectasis (HP:0100750)2.14834423
90Increased neuronal autofluorescent lipopigment (HP:0002074)2.14784587
91Cerebral edema (HP:0002181)2.14599658
92Congenital glaucoma (HP:0001087)2.14219583
93Progressive muscle weakness (HP:0003323)2.11857361
94Rectal prolapse (HP:0002035)2.11386735
95Hyperparathyroidism (HP:0000843)2.11297568
96Hypoplasia of the uterus (HP:0000013)2.11027954
97Partial duplication of the phalanx of hand (HP:0009999)2.10357144
98Abnormality of reticulocytes (HP:0004312)2.09819498
99Hypokalemia (HP:0002900)2.09258647
100Short nail (HP:0001799)2.09028209
101Reduced antithrombin III activity (HP:0001976)2.08076182
102Osteomalacia (HP:0002749)2.07863841
103Macrocytic anemia (HP:0001972)2.07360368
104Delayed CNS myelination (HP:0002188)2.06754488
105Brushfield spots (HP:0001088)2.06078873
106Partial duplication of thumb phalanx (HP:0009944)2.05977598
107Increased hepatocellular lipid droplets (HP:0006565)2.05610689
108Renal Fanconi syndrome (HP:0001994)2.04043143
109Abdominal distention (HP:0003270)2.03967297
110Rough bone trabeculation (HP:0100670)2.03460034
111Absent rod-and cone-mediated responses on ERG (HP:0007688)2.01727850
112Hyperactive renin-angiotensin system (HP:0000841)2.01383462
113Broad distal phalanx of finger (HP:0009836)2.00552632
114Type I diabetes mellitus (HP:0100651)1.98133968
115Primary adrenal insufficiency (HP:0008207)1.98082349
116Overriding aorta (HP:0002623)1.97887972
117Generalized amyotrophy (HP:0003700)1.97604434
118Lipid accumulation in hepatocytes (HP:0006561)1.96572207
119Upper limb amyotrophy (HP:0009129)1.96479064
120Distal upper limb amyotrophy (HP:0007149)1.96479064
121Patent foramen ovale (HP:0001655)1.95898251
122Dicarboxylic aciduria (HP:0003215)1.95584271
123Abnormality of dicarboxylic acid metabolism (HP:0010995)1.95584271
124Reticulocytopenia (HP:0001896)1.94192697
125Exercise intolerance (HP:0003546)1.93540117
126Fragile nails (HP:0001808)1.93397334
127Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.92984354
128Intrahepatic cholestasis (HP:0001406)1.92548587
129Hypoplasia of the pons (HP:0012110)1.91436847
130Down-sloping shoulders (HP:0200021)1.91058113
131Hypothermia (HP:0002045)1.90659058
132Congenital sensorineural hearing impairment (HP:0008527)1.90314970
133Abnormality of magnesium homeostasis (HP:0004921)1.89122278
134Increased CSF lactate (HP:0002490)1.88919033
135Menorrhagia (HP:0000132)1.88418046
136Abnormal rod and cone electroretinograms (HP:0008323)1.88027576
137Exocrine pancreatic insufficiency (HP:0001738)1.86772087
138Elbow flexion contracture (HP:0002987)1.85598928
139Stridor (HP:0010307)1.84518038
140Hypertensive crisis (HP:0100735)1.83333746
141Abnormality of renin-angiotensin system (HP:0000847)1.82420853
142Restlessness (HP:0000711)1.82124152
143Lethargy (HP:0001254)1.81709403
144Pancreatitis (HP:0001733)1.81654897
145Renal duplication (HP:0000075)1.81520117
146Hydroureter (HP:0000072)1.78574986
147Ankle contracture (HP:0006466)1.78395014
148Respiratory failure (HP:0002878)1.77942288
149Renal tubular acidosis (HP:0001947)1.77383358
150Lactic acidosis (HP:0003128)1.76722654
151Abnormality of the tricuspid valve (HP:0001702)1.74785237
152Insomnia (HP:0100785)1.74488644
153Patellar dislocation (HP:0002999)1.73084088
154Spinal rigidity (HP:0003306)1.72572129
155Abnormality of the umbilical cord (HP:0010881)1.72433862
156Hypercalcemia (HP:0003072)1.72025510
157Renal tubular dysfunction (HP:0000124)1.71790620
158Spinal cord compression (HP:0002176)1.71368760
159Genu recurvatum (HP:0002816)1.71144273
160Ileus (HP:0002595)1.71132665
161Prolonged neonatal jaundice (HP:0006579)1.70637528
162Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.70626418
163Selective tooth agenesis (HP:0001592)1.70076255
164Nonimmune hydrops fetalis (HP:0001790)1.70019825
165Ulnar bowing (HP:0003031)1.68709712
166Blue sclerae (HP:0000592)1.68312998
167Flattened epiphyses (HP:0003071)1.67935707
168Slender long bone (HP:0003100)1.67786703
169Hand muscle atrophy (HP:0009130)1.67424606
170Thin bony cortex (HP:0002753)1.67083621
171Flat capital femoral epiphysis (HP:0003370)1.67067444
172Reticulocytosis (HP:0001923)1.66990828
173Double outlet right ventricle (HP:0001719)1.63442408
174Congenital malformation of the right heart (HP:0011723)1.63442408
175Hypercalciuria (HP:0002150)1.62505089
176Hypoplasia of the capital femoral epiphysis (HP:0003090)1.62411303
177Distal lower limb muscle weakness (HP:0009053)1.61854252
178Premature skin wrinkling (HP:0100678)1.60514578

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR4.61206849
2TLK14.42489616
3ERN14.04601886
4MAPK153.62100957
5PASK3.60087884
6TAOK33.57039873
7BCKDK3.33703020
8STK163.27552359
9VRK23.22575821
10SMG12.91452827
11FLT32.61934874
12HIPK22.56809511
13FRK2.54605657
14IRAK32.46688614
15AKT32.31757371
16BRAF2.17667896
17LIMK11.98660150
18EPHB21.92854732
19NME21.89340234
20DYRK31.72133681
21EIF2AK31.68647318
22WNK31.68237780
23ABL21.67091238
24ICK1.66768217
25PIM21.64971814
26EIF2AK11.63938882
27MAP2K21.63323082
28PIK3CG1.61606868
29ARAF1.54498785
30PKN21.53422393
31NEK91.49675239
32EPHA31.49124601
33WNK41.48640416
34TAOK21.44238379
35NME11.40477400
36EEF2K1.37802199
37PAK41.36811656
38FER1.34013528
39MAP3K21.33961124
40EPHA21.33256657
41LRRK21.29338750
42LMTK21.28897940
43IRAK11.24273021
44MAP3K11.20053529
45BRSK21.15333433
46ZAP701.14350407
47PRKCI1.03924333
48AURKA0.99554943
49NLK0.94573128
50DMPK0.87477854
51DYRK1B0.86430688
52PRPF4B0.85516446
53MAP2K30.84297812
54RPS6KA20.81859898
55SRPK10.79670122
56CDK80.78279531
57CASK0.78087338
58UHMK10.77794015
59MUSK0.76403822
60MARK20.72100624
61PDK20.69820438
62MAPKAPK30.69773383
63PHKG20.69253436
64PHKG10.69253436
65TESK20.69068586
66MTOR0.67814008
67TAF10.67624541
68PRKD30.66406532
69PRKD20.65463752
70TAOK10.65234923
71PTK60.65045440
72MAP3K30.64692720
73NEK20.61328250
74MAP3K80.60931360
75DDR20.59887289
76BMX0.59645892
77PAK10.59212727
78CDK70.59072723
79TESK10.58158444
80BLK0.56634451
81TRIB30.56446981
82IRAK40.55359778
83NTRK10.54797992
84DAPK30.54751291
85CAMKK20.54488290
86FES0.53701137
87PDPK10.53678932
88DAPK10.52593811
89DYRK20.52389929
90PTK20.51700913
91VRK10.50802574
92PRKCE0.50371487
93BUB10.50225641
94AURKB0.49783183
95BRSK10.48920517
96MST40.48884323
97RIPK10.46088619
98RPS6KB20.45086671
99AKT20.43710428
100EPHB10.43296588
101CDK90.38806554
102RPS6KC10.38677199
103RPS6KL10.38677199
104CHEK20.38656931
105MAP3K110.38546112
106BMPR1B0.38136639
107CAMK2D0.37714936
108LATS20.35997817
109PAK30.35189346
110ADRBK20.34624918
111SIK10.34393598
112JAK20.33665049
113RPS6KA50.33089536
114PAK20.32912587
115CDK11A0.32650505
116TBK10.32016915
117CSNK2A20.31728480
118ILK0.31618162
119CSNK2A10.31525578
120GRK70.31324878
121MAPKAPK20.31069009
122ADRBK10.30797395
123STK40.30591983
124MET0.29996736
125RPS6KA60.29825981
126CDC42BPA0.29460658
127CAMK2B0.28102036
128IRAK20.27652515
129CSNK1G30.26969265
130MST1R0.26790410
131BTK0.26608779
132TTN0.25863661
133PLK10.24911384
134MYLK0.21900505
135MKNK20.20899213
136RPS6KA40.20879469
137TSSK60.20718696
138FGFR40.20260352
139GSK3A0.19957973
140PRKG20.19918676
141CAMK2G0.19869462
142TEC0.19798757
143KDR0.19162245
144DYRK1A0.19013107
145MAPKAPK50.17393076
146PRKACA0.17311946
147MAPK30.17189870

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030607.46859220
2Maturity onset diabetes of the young_Homo sapiens_hsa049507.24677223
3Protein processing in endoplasmic reticulum_Homo sapiens_hsa041413.19997907
4Sulfur metabolism_Homo sapiens_hsa009202.88696657
5Ribosome_Homo sapiens_hsa030102.87472492
6Folate biosynthesis_Homo sapiens_hsa007902.56982849
7N-Glycan biosynthesis_Homo sapiens_hsa005102.25246182
8Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.03142557
9Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.93844152
10Vibrio cholerae infection_Homo sapiens_hsa051101.79843839
11Vitamin B6 metabolism_Homo sapiens_hsa007501.74688900
12Oxidative phosphorylation_Homo sapiens_hsa001901.70469541
13Insulin secretion_Homo sapiens_hsa049111.60435117
14Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.60246909
15Selenocompound metabolism_Homo sapiens_hsa004501.59696364
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48051770
17Sulfur relay system_Homo sapiens_hsa041221.47981686
18Tryptophan metabolism_Homo sapiens_hsa003801.46510652
19Base excision repair_Homo sapiens_hsa034101.46276332
20Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.40635311
21Biosynthesis of amino acids_Homo sapiens_hsa012301.39764148
22Other glycan degradation_Homo sapiens_hsa005111.33177947
23DNA replication_Homo sapiens_hsa030301.33055715
24Fat digestion and absorption_Homo sapiens_hsa049751.24163716
25Cardiac muscle contraction_Homo sapiens_hsa042601.21943593
26Butanoate metabolism_Homo sapiens_hsa006501.19973299
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.19376887
28Galactose metabolism_Homo sapiens_hsa000521.18901056
29Regulation of autophagy_Homo sapiens_hsa041401.15679674
30Parkinsons disease_Homo sapiens_hsa050121.15195874
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.14248653
32Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.14154824
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.11138982
34Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.11055727
35Pancreatic secretion_Homo sapiens_hsa049721.09359373
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.08924648
37SNARE interactions in vesicular transport_Homo sapiens_hsa041301.01867357
38Alzheimers disease_Homo sapiens_hsa050100.99132947
39Linoleic acid metabolism_Homo sapiens_hsa005910.98964191
40Carbon metabolism_Homo sapiens_hsa012000.97975987
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.97312358
42Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.97187800
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97103511
44Histidine metabolism_Homo sapiens_hsa003400.95731949
45ABC transporters_Homo sapiens_hsa020100.94600090
46Pentose and glucuronate interconversions_Homo sapiens_hsa000400.93732949
47RNA polymerase_Homo sapiens_hsa030200.90527139
48Notch signaling pathway_Homo sapiens_hsa043300.89376674
49Spliceosome_Homo sapiens_hsa030400.88582594
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.88430143
51Peroxisome_Homo sapiens_hsa041460.88308198
52Phenylalanine metabolism_Homo sapiens_hsa003600.88145273
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.88050448
54Fatty acid degradation_Homo sapiens_hsa000710.86865541
55Nucleotide excision repair_Homo sapiens_hsa034200.85834524
56Primary bile acid biosynthesis_Homo sapiens_hsa001200.83735294
57Cyanoamino acid metabolism_Homo sapiens_hsa004600.83723842
58alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.83092242
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.82192917
60Glycosaminoglycan degradation_Homo sapiens_hsa005310.81359128
61Fructose and mannose metabolism_Homo sapiens_hsa000510.81049493
62Basal cell carcinoma_Homo sapiens_hsa052170.79227644
63Type I diabetes mellitus_Homo sapiens_hsa049400.78752984
64Huntingtons disease_Homo sapiens_hsa050160.77243081
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.77197562
66Lysosome_Homo sapiens_hsa041420.76190516
67Tyrosine metabolism_Homo sapiens_hsa003500.73518951
68Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73172481
69Pyrimidine metabolism_Homo sapiens_hsa002400.72458668
70Proteasome_Homo sapiens_hsa030500.70527055
71Steroid biosynthesis_Homo sapiens_hsa001000.70323437
72Circadian rhythm_Homo sapiens_hsa047100.68353849
73Sphingolipid metabolism_Homo sapiens_hsa006000.67330110
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.67140507
75Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66664423
76ECM-receptor interaction_Homo sapiens_hsa045120.66364329
77Metabolic pathways_Homo sapiens_hsa011000.65532045
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64802004
79Bladder cancer_Homo sapiens_hsa052190.63634300
80Arachidonic acid metabolism_Homo sapiens_hsa005900.62635524
81Fatty acid elongation_Homo sapiens_hsa000620.62415645
82Cocaine addiction_Homo sapiens_hsa050300.62011467
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61859503
84Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61735478
85Starch and sucrose metabolism_Homo sapiens_hsa005000.61701994
86Vitamin digestion and absorption_Homo sapiens_hsa049770.60994232
87Central carbon metabolism in cancer_Homo sapiens_hsa052300.60948858
88Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.60544212
89Homologous recombination_Homo sapiens_hsa034400.58590569
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.53015891
91Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.51120230
92Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.49847528
93Mismatch repair_Homo sapiens_hsa034300.49339571
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.47571450
95Thyroid hormone synthesis_Homo sapiens_hsa049180.47520963
96Arginine and proline metabolism_Homo sapiens_hsa003300.47476853
97beta-Alanine metabolism_Homo sapiens_hsa004100.46556977
98Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.46174984
99Pyruvate metabolism_Homo sapiens_hsa006200.45097801
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42993362
101Synaptic vesicle cycle_Homo sapiens_hsa047210.41504763
102Hedgehog signaling pathway_Homo sapiens_hsa043400.40573594
103Collecting duct acid secretion_Homo sapiens_hsa049660.40040372
104Antigen processing and presentation_Homo sapiens_hsa046120.39720055
105Type II diabetes mellitus_Homo sapiens_hsa049300.39572189
106Propanoate metabolism_Homo sapiens_hsa006400.39487189
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.38857446
108Pentose phosphate pathway_Homo sapiens_hsa000300.38727680
109Glucagon signaling pathway_Homo sapiens_hsa049220.37746063
110Thyroid cancer_Homo sapiens_hsa052160.37504926
111Chemical carcinogenesis_Homo sapiens_hsa052040.37364416
112RNA transport_Homo sapiens_hsa030130.35489338
113Protein digestion and absorption_Homo sapiens_hsa049740.34255273
114p53 signaling pathway_Homo sapiens_hsa041150.34085070
115VEGF signaling pathway_Homo sapiens_hsa043700.33184090
116Basal transcription factors_Homo sapiens_hsa030220.32858855
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32338671
118Retinol metabolism_Homo sapiens_hsa008300.31791920
119Melanoma_Homo sapiens_hsa052180.31695055
120Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30771625
121Prion diseases_Homo sapiens_hsa050200.30749683
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.30439290
123Hippo signaling pathway_Homo sapiens_hsa043900.30211831
124Glutathione metabolism_Homo sapiens_hsa004800.28939133
125One carbon pool by folate_Homo sapiens_hsa006700.28232144
126Purine metabolism_Homo sapiens_hsa002300.28029877
127Amphetamine addiction_Homo sapiens_hsa050310.23293054
128Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22328608
129Tight junction_Homo sapiens_hsa045300.22148261
130Prolactin signaling pathway_Homo sapiens_hsa049170.21675764
131Arginine biosynthesis_Homo sapiens_hsa002200.21199512
132Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.20804292
133Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.20067798
134Renin-angiotensin system_Homo sapiens_hsa046140.17558018
135AMPK signaling pathway_Homo sapiens_hsa041520.15144370
136Proteoglycans in cancer_Homo sapiens_hsa052050.14057628

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »