YIPF5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1signal peptide processing (GO:0006465)6.05319602
2COPI coating of Golgi vesicle (GO:0048205)5.77351989
3Golgi transport vesicle coating (GO:0048200)5.77351989
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.66376128
5protein retention in ER lumen (GO:0006621)5.44221377
6protein maturation by protein folding (GO:0022417)4.79949597
7nucleotide transmembrane transport (GO:1901679)4.31127032
8COPII vesicle coating (GO:0048208)4.04587621
9ER overload response (GO:0006983)4.02918967
10type B pancreatic cell proliferation (GO:0044342)3.96374500
11cullin deneddylation (GO:0010388)3.89954783
12protein deneddylation (GO:0000338)3.87592467
13sequestering of extracellular ligand from receptor (GO:0035581)3.87217934
14cell adhesion mediated by integrin (GO:0033627)3.78609578
15nucleotide-sugar biosynthetic process (GO:0009226)3.78294707
16chondrocyte development (GO:0002063)3.58308740
17fatty acid elongation (GO:0030497)3.50740923
18pyrimidine-containing compound transmembrane transport (GO:0072531)3.42889169
19L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.41723655
20regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.40407453
21positive regulation of actin filament depolymerization (GO:0030836)3.40082602
22wound healing, spreading of epidermal cells (GO:0035313)3.34824312
23peptidyl-histidine modification (GO:0018202)3.32685713
24central nervous system myelination (GO:0022010)3.31031902
25axon ensheathment in central nervous system (GO:0032291)3.31031902
26negative regulation of axon extension involved in axon guidance (GO:0048843)3.30222393
27exocrine pancreas development (GO:0031017)3.29724427
28establishment of protein localization to mitochondrial membrane (GO:0090151)3.27901726
29proteasome assembly (GO:0043248)3.25808508
30response to redox state (GO:0051775)3.23414279
31endodermal cell differentiation (GO:0035987)3.23369973
32GDP-mannose metabolic process (GO:0019673)3.23266421
33guanosine-containing compound biosynthetic process (GO:1901070)3.20910540
34negative regulation of axon guidance (GO:1902668)3.16869469
35GTP biosynthetic process (GO:0006183)3.16588607
36collagen fibril organization (GO:0030199)3.16265718
37UDP-N-acetylglucosamine metabolic process (GO:0006047)3.13015993
38dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.12246868
39nucleotide transport (GO:0006862)3.12218927
40short-term memory (GO:0007614)3.11496807
41cellular response to vitamin D (GO:0071305)3.06675869
42positive regulation of protein autophosphorylation (GO:0031954)3.06207952
43GMP metabolic process (GO:0046037)3.05227927
44purine ribonucleotide transport (GO:0015868)3.01867873
45chondrocyte proliferation (GO:0035988)2.97680656
46ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.94205811
47amino acid salvage (GO:0043102)2.92988317
48L-methionine salvage (GO:0071267)2.92988317
49L-methionine biosynthetic process (GO:0071265)2.92988317
50limb bud formation (GO:0060174)2.92689474
51cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.92425909
52vesicle coating (GO:0006901)2.91924435
53nucleotide-sugar metabolic process (GO:0009225)2.86627646
54cellular response to vitamin (GO:0071295)2.85733389
55keratan sulfate catabolic process (GO:0042340)2.85596017
56regulation of integrin-mediated signaling pathway (GO:2001044)2.83275081
57protein neddylation (GO:0045116)2.82700072
58platelet dense granule organization (GO:0060155)2.82035121
59negative chemotaxis (GO:0050919)2.81593238
60regulation of rhodopsin mediated signaling pathway (GO:0022400)2.81222629
61mesenchymal-epithelial cell signaling (GO:0060638)2.79940878
62cell redox homeostasis (GO:0045454)2.79369933
63mitochondrial respiratory chain complex I assembly (GO:0032981)2.75722430
64NADH dehydrogenase complex assembly (GO:0010257)2.75722430
65mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.75722430
66ribonucleoprotein complex disassembly (GO:0032988)2.74774944
67blood vessel maturation (GO:0001955)2.74770894
68cholesterol biosynthetic process (GO:0006695)2.74561624
69deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.72923805
70eye photoreceptor cell differentiation (GO:0001754)2.72285827
71photoreceptor cell differentiation (GO:0046530)2.72285827
72regulation of cellular amino acid metabolic process (GO:0006521)2.70412708
73skin morphogenesis (GO:0043589)2.70263345
74ventricular cardiac muscle cell development (GO:0055015)2.69628988
75extracellular regulation of signal transduction (GO:1900115)2.69344306
76extracellular negative regulation of signal transduction (GO:1900116)2.69344306
77peptide hormone processing (GO:0016486)2.67248751
78regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.67062171
79ER to Golgi vesicle-mediated transport (GO:0006888)2.66673480
80regulation of metalloenzyme activity (GO:0048552)2.66168133
81positive regulation of extracellular matrix organization (GO:1903055)2.65913548
82regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.65530035
83anterior/posterior axis specification, embryo (GO:0008595)2.65480499
84organelle disassembly (GO:1903008)2.64848773
85regulation of type B pancreatic cell apoptotic process (GO:2000674)2.64829475
86peptidyl-proline hydroxylation (GO:0019511)2.62968586
87endocrine pancreas development (GO:0031018)2.62322405
88lipid particle organization (GO:0034389)2.61938841
89kidney mesenchyme development (GO:0072074)2.61413631
90negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.60556114
91lymphangiogenesis (GO:0001946)2.60282019
92rhodopsin mediated signaling pathway (GO:0016056)2.59787097
93hemidesmosome assembly (GO:0031581)2.59390439
94UTP biosynthetic process (GO:0006228)2.57820989
95protein N-linked glycosylation via asparagine (GO:0018279)2.57611031
96peptidyl-proline modification (GO:0018208)2.57196748
97erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.56985843
98L-phenylalanine catabolic process (GO:0006559)2.56985843
99protein heterotrimerization (GO:0070208)2.56956997
100protein complex biogenesis (GO:0070271)2.56805115
101chaperone-mediated protein transport (GO:0072321)2.56182458
102protein peptidyl-prolyl isomerization (GO:0000413)2.55750661
103L-serine metabolic process (GO:0006563)2.52778853
104retina vasculature morphogenesis in camera-type eye (GO:0061299)2.52093778
105sterol biosynthetic process (GO:0016126)2.51352286
106response to lead ion (GO:0010288)2.50975672
107substrate-dependent cell migration (GO:0006929)2.50682458
108magnesium ion transport (GO:0015693)2.50106349
109retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.50081926
110extracellular fibril organization (GO:0043206)2.49735319
111water-soluble vitamin biosynthetic process (GO:0042364)2.49241257
112peptidyl-asparagine modification (GO:0018196)2.48251320
113negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.48221842
114mannosylation (GO:0097502)2.47933365
115cell migration involved in sprouting angiogenesis (GO:0002042)2.46606301
116nucleoside diphosphate phosphorylation (GO:0006165)2.46126534
117ribosome assembly (GO:0042255)2.45834862
118mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.45596749
119mesodermal cell differentiation (GO:0048333)2.44979806
120activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.44878415
121positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.43971908
122negative regulation of chondrocyte differentiation (GO:0032331)2.43069586
123deoxyribose phosphate biosynthetic process (GO:0046385)2.42691517
1242-deoxyribonucleotide biosynthetic process (GO:0009265)2.42691517
125protein N-linked glycosylation (GO:0006487)2.42609921
126sphingomyelin metabolic process (GO:0006684)2.42339352
1273-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.42125780
128purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.42125780
129L-serine transport (GO:0015825)2.41786495
130folic acid transport (GO:0015884)2.40929996
131negative regulation of nitric-oxide synthase activity (GO:0051001)2.39811955
132sequestering of metal ion (GO:0051238)2.38907512
133neuron projection extension involved in neuron projection guidance (GO:1902284)2.38714798
134axon extension involved in axon guidance (GO:0048846)2.38714798
135response to pheromone (GO:0019236)2.38218563
136chaperone-mediated protein folding (GO:0061077)2.38083813
137cellular response to topologically incorrect protein (GO:0035967)2.37518152
138cell aggregation (GO:0098743)2.37332047
139cartilage condensation (GO:0001502)2.37332047
140UTP metabolic process (GO:0046051)2.36818840
141cellular response to unfolded protein (GO:0034620)2.36678093
142wound healing, spreading of cells (GO:0044319)2.36102347
143substrate adhesion-dependent cell spreading (GO:0034446)2.36101264
144protein hydroxylation (GO:0018126)2.35085364
145glucosamine-containing compound catabolic process (GO:1901072)2.35078946
146metanephric mesenchyme development (GO:0072075)2.35011476
147intraciliary transport (GO:0042073)2.34979220
148positive regulation of nuclease activity (GO:0032075)2.34345730
149negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.34271281
150negative regulation of ligase activity (GO:0051352)2.34271281
151branched-chain amino acid catabolic process (GO:0009083)2.33595348
152isoprenoid biosynthetic process (GO:0008299)2.32918291
153endoplasmic reticulum unfolded protein response (GO:0030968)2.32477150
154regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.31187091
155response to misfolded protein (GO:0051788)2.30553717
156heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.30254419
157regulation of hexokinase activity (GO:1903299)2.29920312
158tRNA aminoacylation for protein translation (GO:0006418)2.27769102
159regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.27211021
160amino acid activation (GO:0043038)2.27163670
161tRNA aminoacylation (GO:0043039)2.27163670
162ganglion development (GO:0061548)2.27065507
163smooth muscle tissue development (GO:0048745)2.26381445
164positive regulation of macrophage activation (GO:0043032)2.25511445
165DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.25064750
166vascular smooth muscle contraction (GO:0014829)2.23701215
167regulation of plasminogen activation (GO:0010755)2.22570490
168cilium morphogenesis (GO:0060271)2.21661726
169negative regulation of endothelial cell proliferation (GO:0001937)2.18923884
170intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.16956596

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.16348644
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.83837127
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.83618372
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.04899979
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.76723900
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.74138474
7VDR_22108803_ChIP-Seq_LS180_Human2.73306553
8PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.67045104
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.50995694
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.43747942
11SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.43020502
12PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.25410747
13SALL1_21062744_ChIP-ChIP_HESCs_Human2.23553590
14CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.15349205
15* BRD4_25478319_ChIP-Seq_HGPS_Human2.05562223
16CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.01040823
17SMAD_19615063_ChIP-ChIP_OVARY_Human1.99505833
18* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.96894443
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.94765815
20ZNF274_21170338_ChIP-Seq_K562_Hela1.92134883
21SRF_21415370_ChIP-Seq_HL-1_Mouse1.88467181
22POU3F2_20337985_ChIP-ChIP_501MEL_Human1.88409354
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.87696630
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.85467707
25CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.85251455
26ETS1_20019798_ChIP-Seq_JURKAT_Human1.83720549
27WT1_19549856_ChIP-ChIP_CCG9911_Human1.83712898
28DCP1A_22483619_ChIP-Seq_HELA_Human1.78678833
29DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.75338223
30TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.74951375
31ELK1_19687146_ChIP-ChIP_HELA_Human1.72579150
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.70901546
33ELK1_22589737_ChIP-Seq_MCF10A_Human1.68547713
34* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.66017071
35* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.66017071
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.64717990
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.60662336
38ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.55298552
39* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.54995556
40E2F1_18555785_ChIP-Seq_MESCs_Mouse1.54951850
41* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.52481598
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52402596
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40160843
44ELF1_17652178_ChIP-ChIP_JURKAT_Human1.39921370
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39437974
46* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.38424101
47SOX17_20123909_ChIP-Seq_XEN_Mouse1.34750120
48CTBP2_25329375_ChIP-Seq_LNCAP_Human1.34310271
49* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34031198
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.32049720
51* GABP_19822575_ChIP-Seq_HepG2_Human1.30349817
52CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.29394090
53MYC_18555785_ChIP-Seq_MESCs_Mouse1.28922472
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.28350848
55P300_19829295_ChIP-Seq_ESCs_Human1.26868824
56CLOCK_20551151_ChIP-Seq_293T_Human1.25252150
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.23607602
58BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.23307653
59GBX2_23144817_ChIP-Seq_PC3_Human1.22802334
60FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.22633998
61EGR1_23403033_ChIP-Seq_LIVER_Mouse1.22525668
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21086016
63EP300_21415370_ChIP-Seq_HL-1_Mouse1.20578984
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.20110872
65TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.19153188
66MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.18081970
67ER_23166858_ChIP-Seq_MCF-7_Human1.17698842
68IGF1R_20145208_ChIP-Seq_DFB_Human1.15919723
69NFE2_27457419_Chip-Seq_LIVER_Mouse1.15700202
70FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.15431298
71SMAD4_21799915_ChIP-Seq_A2780_Human1.13957085
72VDR_23849224_ChIP-Seq_CD4+_Human1.13573631
73HIF1A_21447827_ChIP-Seq_MCF-7_Human1.13465460
74HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.13410056
75ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.12756992
76FUS_26573619_Chip-Seq_HEK293_Human1.12269666
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.11819559
78CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.11648717
79CDX2_22108803_ChIP-Seq_LS180_Human1.09349597
80MYC_18358816_ChIP-ChIP_MESCs_Mouse1.08401285
81PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.08343356
82MYC_18940864_ChIP-ChIP_HL60_Human1.08029212
83TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07981790
84BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06747537
85REST_19997604_ChIP-ChIP_NEURONS_Mouse1.06333225
86CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05755309
87TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05096225
88SALL4_18804426_ChIP-ChIP_XEN_Mouse1.04539264
89HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.03018103
90HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01353131
91FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.01142006
92FLI1_27457419_Chip-Seq_LIVER_Mouse1.01108627
93TP53_16413492_ChIP-PET_HCT116_Human1.00955156
94PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00683473
95AR_21909140_ChIP-Seq_LNCAP_Human1.00401633
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.00241387
97HTT_18923047_ChIP-ChIP_STHdh_Human0.99944393
98NANOG_19829295_ChIP-Seq_ESCs_Human0.99651051
99SOX2_19829295_ChIP-Seq_ESCs_Human0.99651051
100AR_20517297_ChIP-Seq_VCAP_Human0.98896367
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98597075
102AR_21572438_ChIP-Seq_LNCaP_Human0.98561197
103CJUN_26792858_Chip-Seq_BT549_Human0.98068980
104FOXM1_26456572_ChIP-Seq_MCF-7_Human0.98016997
105TP63_17297297_ChIP-ChIP_HaCaT_Human0.97729144
106MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97395466
107P53_22387025_ChIP-Seq_ESCs_Mouse0.96555647
108GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96331029
109SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.96191646
110SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.96191646
111ERG_20517297_ChIP-Seq_VCAP_Human0.95881583
112TP53_18474530_ChIP-ChIP_U2OS_Human0.95662741
113* CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.95587006
114NANOG_16153702_ChIP-ChIP_HESCs_Human0.95507359
115* PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95405080
116FOXP3_21729870_ChIP-Seq_TREG_Human0.95136230
117JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94802500
118CBP_20019798_ChIP-Seq_JUKART_Human0.94639631
119IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94639631
120NELFA_20434984_ChIP-Seq_ESCs_Mouse0.94346929
121UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93844575
122CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92799307
123SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.92698271
124SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92483467
125EWS_26573619_Chip-Seq_HEK293_Human0.91860033
126SOX2_20726797_ChIP-Seq_SW620_Human0.91422160
127EZH2_27294783_Chip-Seq_NPCs_Mouse0.91255725
128PIAS1_25552417_ChIP-Seq_VCAP_Human0.90189645
129GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89770360
130RXR_22158963_ChIP-Seq_LIVER_Mouse0.88541836
131CRX_20693478_ChIP-Seq_RETINA_Mouse0.87670020
132TAL1_26923725_Chip-Seq_HPCs_Mouse0.86843417
133STAT3_18555785_Chip-Seq_ESCs_Mouse0.86092393
134JUN_21703547_ChIP-Seq_K562_Human0.85777097
135EED_16625203_ChIP-ChIP_MESCs_Mouse0.85247258
136TAF15_26573619_Chip-Seq_HEK293_Human0.84186786
137POU5F1_16153702_ChIP-ChIP_HESCs_Human0.83964717
138MYC_19030024_ChIP-ChIP_MESCs_Mouse0.83696709
139NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.83015038
140NANOG_18555785_Chip-Seq_ESCs_Mouse0.82736467
141ZFX_18555785_ChIP-Seq_MESCs_Mouse0.82475066
142* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.82159869
143EOMES_21245162_ChIP-Seq_HESCs_Human0.81451988

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.28740707
2MP0005503_abnormal_tendon_morphology4.31964875
3MP0009384_cardiac_valve_regurgitation3.49343179
4MP0001542_abnormal_bone_strength3.43520657
5MP0003195_calcinosis2.95824892
6MP0003941_abnormal_skin_development2.92422787
7MP0005275_abnormal_skin_tensile2.58560675
8MP0005220_abnormal_exocrine_pancreas2.57610754
9MP0005623_abnormal_meninges_morphology2.28110691
10MP0002282_abnormal_trachea_morphology2.27433997
11MP0003806_abnormal_nucleotide_metabolis2.19174773
12MP0002295_abnormal_pulmonary_circulatio2.16597102
13MP0005084_abnormal_gallbladder_morpholo2.15627501
14MP0004134_abnormal_chest_morphology2.06458990
15MP0003011_delayed_dark_adaptation1.96056480
16MP0006054_spinal_hemorrhage1.92764286
17MP0010368_abnormal_lymphatic_system1.90685660
18MP0005508_abnormal_skeleton_morphology1.89312082
19MP0009250_abnormal_appendicular_skeleto1.87874271
20MP0003566_abnormal_cell_adhesion1.87252693
21MP0000163_abnormal_cartilage_morphology1.82205544
22MP0002933_joint_inflammation1.81524240
23MP0002102_abnormal_ear_morphology1.80808147
24MP0005551_abnormal_eye_electrophysiolog1.77572589
25MP0000013_abnormal_adipose_tissue1.77056569
26MP0003279_aneurysm1.72561709
27MP0004043_abnormal_pH_regulation1.67035142
28MP0003136_yellow_coat_color1.66326863
29MP0003950_abnormal_plasma_membrane1.64492655
30MP0002896_abnormal_bone_mineralization1.61539494
31MP0001666_abnormal_nutrient_absorption1.61326091
32MP0009780_abnormal_chondrocyte_physiolo1.59647175
33MP0009697_abnormal_copulation1.57990702
34MP0000049_abnormal_middle_ear1.55098429
35MP0001299_abnormal_eye_distance/1.55058357
36MP0003718_maternal_effect1.54671762
37MP0005365_abnormal_bile_salt1.53280367
38MP0002139_abnormal_hepatobiliary_system1.53095937
39MP0010386_abnormal_urinary_bladder1.51804023
40MP0001984_abnormal_olfaction1.48081809
41MP0001879_abnormal_lymphatic_vessel1.47545509
42MP0005187_abnormal_penis_morphology1.45479168
43MP0005379_endocrine/exocrine_gland_phen1.45357782
44MP0005083_abnormal_biliary_tract1.44079987
45MP0005171_absent_coat_pigmentation1.40504178
46MP0005646_abnormal_pituitary_gland1.40204181
47MP0001986_abnormal_taste_sensitivity1.39206164
48MP0002938_white_spotting1.37087883
49MP0000462_abnormal_digestive_system1.36517186
50MP0005257_abnormal_intraocular_pressure1.35320673
51MP0002115_abnormal_skeleton_extremities1.35024949
52MP0009379_abnormal_foot_pigmentation1.34338096
53MP0001944_abnormal_pancreas_morphology1.34180245
54MP0001905_abnormal_dopamine_level1.33712504
55MP0006072_abnormal_retinal_apoptosis1.33634208
56MP0000569_abnormal_digit_pigmentation1.33565121
57MP0005595_abnormal_vascular_smooth1.31902064
58MP0004272_abnormal_basement_membrane1.31622247
59MP0005197_abnormal_uvea_morphology1.27226925
60MP0000767_abnormal_smooth_muscle1.26828399
61MP0005332_abnormal_amino_acid1.25579051
62MP0005023_abnormal_wound_healing1.25434197
63MP0010030_abnormal_orbit_morphology1.25380141
64MP0005085_abnormal_gallbladder_physiolo1.25028201
65MP0005390_skeleton_phenotype1.23718851
66MP0003186_abnormal_redox_activity1.23148195
67MP0010352_gastrointestinal_tract_polyps1.22322246
68MP0000647_abnormal_sebaceous_gland1.22225571
69MP0002876_abnormal_thyroid_physiology1.21845359
70MP0003283_abnormal_digestive_organ1.21121273
71MP0001529_abnormal_vocalization1.14775019
72MP0000372_irregular_coat_pigmentation1.13616284
73MP0005253_abnormal_eye_physiology1.12510144
74MP0000762_abnormal_tongue_morphology1.12331350
75MP0003385_abnormal_body_wall1.11542622
76MP0005408_hypopigmentation1.10251284
77MP0005360_urolithiasis1.07354900
78MP0001243_abnormal_dermal_layer1.04226379
79MP0000613_abnormal_salivary_gland1.02764140
80MP0009053_abnormal_anal_canal1.01457722
81MP0002108_abnormal_muscle_morphology1.01094369
82MP0002113_abnormal_skeleton_development1.00999579
83MP0003705_abnormal_hypodermis_morpholog1.00340613
84MP0003795_abnormal_bone_structure1.00055779
85MP0001661_extended_life_span0.99015864
86MP0002163_abnormal_gland_morphology0.98203111
87MP0003755_abnormal_palate_morphology0.97841650
88MP0003122_maternal_imprinting0.97698801
89MP0005367_renal/urinary_system_phenotyp0.97535414
90MP0000516_abnormal_urinary_system0.97535414
91MP0000538_abnormal_urinary_bladder0.97124824
92MP0001764_abnormal_homeostasis0.96857349
93MP0002234_abnormal_pharynx_morphology0.96624260
94MP0000749_muscle_degeneration0.95709203
95MP0001958_emphysema0.95072516
96MP0005395_other_phenotype0.94481920
97MP0002177_abnormal_outer_ear0.94130449
98MP0002693_abnormal_pancreas_physiology0.93270430
99MP0008004_abnormal_stomach_pH0.93019648
100MP0001533_abnormal_skeleton_physiology0.92082829
101MP0000427_abnormal_hair_cycle0.91528651
102MP0001293_anophthalmia0.91399540
103MP0005193_abnormal_anterior_eye0.88598161
104MP0008932_abnormal_embryonic_tissue0.87895308
105MP0003937_abnormal_limbs/digits/tail_de0.86764077
106MP0005164_abnormal_response_to0.86703167
107MP0002638_abnormal_pupillary_reflex0.86152128
108MP0001177_atelectasis0.85583846
109MP0000681_abnormal_thyroid_gland0.84273005
110MP0005058_abnormal_lysosome_morphology0.84181541
111MP0000534_abnormal_ureter_morphology0.84063963
112MP0002089_abnormal_postnatal_growth/wei0.83863856
113MP0003252_abnormal_bile_duct0.83796317
114MP0003942_abnormal_urinary_system0.82793931
115MP0003315_abnormal_perineum_morphology0.82308371
116MP0004782_abnormal_surfactant_physiolog0.81042925
117MP0008007_abnormal_cellular_replicative0.80304339
118MP0000639_abnormal_adrenal_gland0.79471717
119MP0008789_abnormal_olfactory_epithelium0.79403476
120MP0003191_abnormal_cellular_cholesterol0.79181961
121MP0000920_abnormal_myelination0.79164217
122MP0003868_abnormal_feces_composition0.77219700
123MP0002060_abnormal_skin_morphology0.76837130
124MP0002697_abnormal_eye_size0.76832326
125MP0002109_abnormal_limb_morphology0.76054413
126MP0003935_abnormal_craniofacial_develop0.75780735
127MP0003091_abnormal_cell_migration0.75709752
128MP0002751_abnormal_autonomic_nervous0.72603386
129MP0005165_increased_susceptibility_to0.72069284
130MP0001664_abnormal_digestion0.72038370
131MP0005195_abnormal_posterior_eye0.71924182
132MP0001188_hyperpigmentation0.71840753
133MP0002233_abnormal_nose_morphology0.70744878
134MP0001286_abnormal_eye_development0.69667250
135MP0000230_abnormal_systemic_arterial0.69375342
136MP0004133_heterotaxia0.69274242
137MP0002249_abnormal_larynx_morphology0.68404675
138MP0000358_abnormal_cell_content/0.68150845
139MP0009840_abnormal_foam_cell0.68056452
140MP0003329_amyloid_beta_deposits0.67203284
141MP0004957_abnormal_blastocyst_morpholog0.66326147
142MP0002116_abnormal_craniofacial_bone0.66288327
143MP0002084_abnormal_developmental_patter0.66104364
144MP0005451_abnormal_body_composition0.65972122
145MP0002932_abnormal_joint_morphology0.65947735
146MP0002090_abnormal_vision0.65268919
147MP0000537_abnormal_urethra_morphology0.63751140
148MP0000428_abnormal_craniofacial_morphol0.62036386

Predicted human phenotypes

RankGene SetZ-score
1Epiphyseal dysplasia (HP:0002656)4.99068419
2Irregular epiphyses (HP:0010582)4.75000198
3Premature rupture of membranes (HP:0001788)4.28901841
4Flat capital femoral epiphysis (HP:0003370)3.96998231
5Vitreoretinal degeneration (HP:0000655)3.86426377
6Vascular tortuosity (HP:0004948)3.83680351
7Atrophic scars (HP:0001075)3.80367160
8Small epiphyses (HP:0010585)3.50016514
9Protrusio acetabuli (HP:0003179)3.47770457
10Cupped ribs (HP:0000887)3.43270665
11Ankle contracture (HP:0006466)3.40194343
12Arterial tortuosity (HP:0005116)3.39214660
13Abnormality of dentin (HP:0010299)3.36694091
14Neonatal short-limb short stature (HP:0008921)3.17330598
15Delayed gross motor development (HP:0002194)3.16982991
16Congenital stationary night blindness (HP:0007642)3.09763229
17Aortic aneurysm (HP:0004942)3.09105937
18Abnormal tarsal ossification (HP:0008369)3.05812401
19Delayed epiphyseal ossification (HP:0002663)2.92757637
20Cervical subluxation (HP:0003308)2.90839656
21Irregular vertebral endplates (HP:0003301)2.82070467
22Osteoarthritis (HP:0002758)2.80291823
23Biconcave vertebral bodies (HP:0004586)2.78910765
24Abnormality of the vertebral endplates (HP:0005106)2.76104678
25Vertebral compression fractures (HP:0002953)2.75861728
26Genu varum (HP:0002970)2.75142039
27Bladder diverticulum (HP:0000015)2.70557012
28Beaking of vertebral bodies (HP:0004568)2.66874626
29Soft skin (HP:0000977)2.59537184
30Protuberant abdomen (HP:0001538)2.38237086
31Abnormality of the proximal phalanges of the hand (HP:0009834)2.38102865
32Disproportionate short-trunk short stature (HP:0003521)2.37288871
33Abnormality of the femoral head (HP:0003368)2.36204620
34Recurrent corneal erosions (HP:0000495)2.35239419
35Hypoglycemic seizures (HP:0002173)2.34187588
36True hermaphroditism (HP:0010459)2.33900441
37Absent epiphyses (HP:0010577)2.33541656
38Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.33541656
39Adrenal hypoplasia (HP:0000835)2.32057187
40Cardiovascular calcification (HP:0011915)2.30664890
41Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.30575008
42Abnormality of femoral epiphyses (HP:0006499)2.30575008
43Congenital primary aphakia (HP:0007707)2.30256725
44Hypoplasia of the odontoid process (HP:0003311)2.30207671
45Fragile skin (HP:0001030)2.29366307
46Flattened epiphyses (HP:0003071)2.27856013
47Flared iliac wings (HP:0002869)2.24863076
48Mesomelia (HP:0003027)2.23821389
49Gait imbalance (HP:0002141)2.22372711
50Medial flaring of the eyebrow (HP:0010747)2.21668570
51Acute necrotizing encephalopathy (HP:0006965)2.21319082
52Abnormality of glycolysis (HP:0004366)2.20050746
53Increased serum pyruvate (HP:0003542)2.20050746
54Metaphyseal irregularity (HP:0003025)2.18917220
55Abnormality of the epiphysis of the femoral head (HP:0010574)2.17569931
56Symptomatic seizures (HP:0011145)2.17562219
57Glossoptosis (HP:0000162)2.16274524
58Hyperinsulinemic hypoglycemia (HP:0000825)2.16189607
59Platyspondyly (HP:0000926)2.16093113
60Short femoral neck (HP:0100864)2.14567381
61Abnormality of the phalanges of the 2nd finger (HP:0009541)2.14487158
62Barrel-shaped chest (HP:0001552)2.12351233
63Redundant skin (HP:0001582)2.11275969
64Spondylolisthesis (HP:0003302)2.10498324
65Abnormality of aromatic amino acid family metabolism (HP:0004338)2.09847190
66Coxa vara (HP:0002812)2.09133372
67Abnormal mitochondria in muscle tissue (HP:0008316)2.06260982
68Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.05960419
69Keratoconus (HP:0000563)2.05017047
70Increased corneal curvature (HP:0100692)2.05017047
71Hypoplastic ischia (HP:0003175)2.04416744
72Acute encephalopathy (HP:0006846)2.04072748
73Follicular hyperkeratosis (HP:0007502)2.02670869
74Abnormality of methionine metabolism (HP:0010901)2.01689134
75Spinal rigidity (HP:0003306)2.01091088
76Mild short stature (HP:0003502)2.01068420
77Coronal craniosynostosis (HP:0004440)1.99696484
78Abnormality of the intrinsic pathway (HP:0010989)1.99531884
79Joint stiffness (HP:0001387)1.99024920
80Hypoplastic pelvis (HP:0008839)1.97817692
81Increased CSF lactate (HP:0002490)1.97657826
82Bifid tongue (HP:0010297)1.94440890
83Stillbirth (HP:0003826)1.93901425
84Nephrogenic diabetes insipidus (HP:0009806)1.93451192
85Renal Fanconi syndrome (HP:0001994)1.92583717
86Aplasia/Hypoplasia involving the vertebral column (HP:0008518)1.92434013
87Abnormality of the ischium (HP:0003174)1.92247548
88Metaphyseal dysplasia (HP:0100255)1.92058887
89Abnormal foot bone ossification (HP:0010675)1.91414371
90Thoracolumbar scoliosis (HP:0002944)1.90730861
91Aortic valve stenosis (HP:0001650)1.90730098
92Pancreatic fibrosis (HP:0100732)1.89945363
93Wormian bones (HP:0002645)1.89587595
94Fat malabsorption (HP:0002630)1.88748964
95Steatorrhea (HP:0002570)1.87790075
96Tetraparesis (HP:0002273)1.86579657
97Abnormality of midbrain morphology (HP:0002418)1.85711407
98Molar tooth sign on MRI (HP:0002419)1.85711407
99Short tibia (HP:0005736)1.85249495
100Abnormality of carpal bone ossification (HP:0006257)1.83979893
101Ovoid vertebral bodies (HP:0003300)1.83644591
102Abnormal epiphyseal ossification (HP:0010656)1.83551890
103Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.82403700
104Autoamputation (HP:0001218)1.82180451
105Mitral stenosis (HP:0001718)1.82030745
106Mitochondrial inheritance (HP:0001427)1.81880919
107Abnormality of the acetabulum (HP:0003170)1.81559879
108Arthropathy (HP:0003040)1.80924104
109Bowel diverticulosis (HP:0005222)1.80917657
110Blue sclerae (HP:0000592)1.79478981
111Abnormality of proline metabolism (HP:0010907)1.78968023
112Hydroxyprolinuria (HP:0003080)1.78968023
113Broad metatarsal (HP:0001783)1.78247751
114Progressive macrocephaly (HP:0004481)1.77774144
115Vaginal atresia (HP:0000148)1.77729614
116Aortic regurgitation (HP:0001659)1.77387221
117Dilatation of the ascending aorta (HP:0005111)1.76437844
118Short nail (HP:0001799)1.76093747
119Abnormality of the odontoid process (HP:0003310)1.75783870
120Type I transferrin isoform profile (HP:0003642)1.75666568
121Congenital, generalized hypertrichosis (HP:0004540)1.75653109
122Osteolytic defects of the hand bones (HP:0009699)1.74609505
123Osteolytic defects of the phalanges of the hand (HP:0009771)1.74609505
124Genital tract atresia (HP:0001827)1.73860619
125Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.73446718
126Abnormal vertebral ossification (HP:0100569)1.73310328
127Neoplasm of the peripheral nervous system (HP:0100007)1.73252748
128Entropion (HP:0000621)1.72872628
129Aplasia/Hypoplasia of the tongue (HP:0010295)1.72730204
130Abnormality of the middle phalanges of the toes (HP:0010183)1.72232346
131Abnormal protein glycosylation (HP:0012346)1.71972153
132Abnormal glycosylation (HP:0012345)1.71972153
133Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.71972153
134Abnormal protein N-linked glycosylation (HP:0012347)1.71972153
135Cerebral hypomyelination (HP:0006808)1.71202167
136Reduced antithrombin III activity (HP:0001976)1.71111713
137Wrist flexion contracture (HP:0001239)1.71095129
138Poor head control (HP:0002421)1.70917332
139Retinal dysplasia (HP:0007973)1.70770197
140Abnormal delivery (HP:0001787)1.70643414
141Aplasia/Hypoplasia of the lens (HP:0008063)1.70234249
142Genu recurvatum (HP:0002816)1.70216520
143Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.70032332
144Spastic paraparesis (HP:0002313)1.69666141
145Aortic dissection (HP:0002647)1.67978193
146Patchy hypopigmentation of hair (HP:0011365)1.66435657
147Methylmalonic acidemia (HP:0002912)1.66364534
148Abnormality of aspartate family amino acid metabolism (HP:0010899)1.64732546
149Increased hepatocellular lipid droplets (HP:0006565)1.63680016
150Limb-girdle muscle atrophy (HP:0003797)1.63425949
151Renal cortical cysts (HP:0000803)1.62442343
152Stenosis of the external auditory canal (HP:0000402)1.62213565
153Aplasia/Hypoplasia of the tibia (HP:0005772)1.62102597
154Sparse eyelashes (HP:0000653)1.61602861
155Pancreatic cysts (HP:0001737)1.60149454
156Nonimmune hydrops fetalis (HP:0001790)1.59644352
157Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.59179016
158Abnormality of alanine metabolism (HP:0010916)1.59179016
159Hyperalaninemia (HP:0003348)1.59179016
160Hyperextensible skin (HP:0000974)1.58741611
161Sensory axonal neuropathy (HP:0003390)1.57995738
162Onycholysis (HP:0001806)1.56246062
163Pulmonary artery stenosis (HP:0004415)1.51660938
164Upper limb muscle weakness (HP:0003484)1.50018226

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK3.51345937
2STK163.38457421
3PBK2.92999417
4EIF2AK32.80019907
5TRIM282.74037303
6FRK2.58500632
7MAP3K122.47032451
8BCR2.44691544
9ARAF2.41355818
10PIM22.36761172
11INSRR2.32879077
12DDR22.23634984
13NEK12.21743279
14BUB12.17938782
15EPHB21.98963589
16STK391.97970492
17EIF2AK11.96593329
18TGFBR21.88160959
19NEK61.84643012
20CASK1.84090585
21STK38L1.83377706
22NME11.78935634
23BMPR21.73284512
24DYRK21.73137442
25BRAF1.72109458
26LIMK11.60948630
27AKT31.48988138
28CDK81.48099581
29MET1.47309337
30PLK21.45616880
31TSSK61.44557199
32BMPR1B1.42941466
33NUAK11.41687058
34NME21.39004029
35FLT31.37795332
36TIE11.30305763
37MAPK151.28700893
38TESK21.26869288
39MAP4K21.26538053
40OXSR11.25472573
41ERN11.24021239
42ACVR1B1.21420961
43MOS1.21347896
44NEK91.17021077
45WNK41.15617469
46PASK1.15540558
47CSNK1G31.13558876
48PTK21.13558173
49PIK3CA1.13453790
50MAPKAPK51.12472056
51PIK3CG1.12461576
52TGFBR11.09818614
53PDGFRA1.08448361
54ERBB31.08375990
55TESK11.05697838
56MAP3K31.04203787
57IRAK11.04117220
58TAOK31.01760251
59ERBB41.01497042
60PDK21.01020898
61PLK31.00819447
62MKNK20.95617952
63MKNK10.94384953
64BRSK20.93812203
65CSNK1G10.91999195
66MST40.91441175
67PAK20.90990292
68CCNB10.88863339
69PAK40.88761278
70EPHA30.85883367
71CAMKK20.84294845
72CLK10.83536284
73ADRBK20.83281706
74CAMK2B0.83121161
75CAMK2D0.82369557
76PAK30.81689451
77ZAK0.81304296
78PRKCE0.81134703
79VRK10.79916057
80MYLK0.78553996
81LATS10.77663603
82DYRK1A0.76718288
83ABL20.75631069
84STK30.75124725
85GRK70.74854800
86PLK40.73191831
87PRKCI0.72208965
88PNCK0.72003345
89PINK10.71864411
90CAMK2G0.64956679
91FER0.63660106
92AURKA0.63637546
93CSNK1A1L0.63150811
94CDK140.62995603
95MAP3K40.62708928
96MST1R0.62116560
97CSNK1G20.59958311
98TTK0.58517682
99RPS6KA40.58271500
100ILK0.58214007
101GRK10.58109095
102STK380.57075420
103LATS20.56235221
104CAMK2A0.56220664
105PRKCG0.55410543
106IRAK30.54117624
107PLK10.54110898
108MAPKAPK30.53762098
109ROCK10.53686654
110BRSK10.52563684
111VRK20.52127878
112IRAK20.51758104
113STK240.50878926
114TRPM70.48925477
115RPS6KA50.48803764
116EIF2AK20.48134447
117MAP2K70.47146171
118PAK60.46856348
119ROCK20.46522089
120ADRBK10.46144118
121SRPK10.43858506
122DYRK1B0.43318966
123GSK3A0.43240644
124EPHA20.43212948
125MAPK70.43118279
126FGFR20.42486102
127IRAK40.42179883
128LMTK20.41372778
129NLK0.41146540
130FGFR10.41023148
131PDGFRB0.39877069
132MAPK130.39207152
133WEE10.38489004
134PRKG20.38200381
135NTRK10.36302291
136TNIK0.34869409
137CSNK2A10.34211189
138CDK30.33708179
139CSNK1A10.33699587
140WNK30.33110418
141CDK180.33056014

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030606.28295572
2Sulfur metabolism_Homo sapiens_hsa009203.36968960
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.93616520
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.80372137
5Steroid biosynthesis_Homo sapiens_hsa001002.51806367
6Phototransduction_Homo sapiens_hsa047442.41973323
7Proteasome_Homo sapiens_hsa030502.38682964
8Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.34351304
9Folate biosynthesis_Homo sapiens_hsa007902.24353873
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.19020116
11Fatty acid elongation_Homo sapiens_hsa000622.12106183
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.09403758
13Oxidative phosphorylation_Homo sapiens_hsa001902.06919664
14Vibrio cholerae infection_Homo sapiens_hsa051102.04936437
15Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.73045846
16Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.71285404
17Sphingolipid metabolism_Homo sapiens_hsa006001.69026002
18Vitamin B6 metabolism_Homo sapiens_hsa007501.67201999
19Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.63193796
20RNA polymerase_Homo sapiens_hsa030201.60947615
21Protein digestion and absorption_Homo sapiens_hsa049741.56174320
22Vitamin digestion and absorption_Homo sapiens_hsa049771.46022314
23SNARE interactions in vesicular transport_Homo sapiens_hsa041301.44942029
24Parkinsons disease_Homo sapiens_hsa050121.43796785
25Arginine and proline metabolism_Homo sapiens_hsa003301.38860530
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.33021244
27N-Glycan biosynthesis_Homo sapiens_hsa005101.32661942
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.31201011
29Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.25951817
30p53 signaling pathway_Homo sapiens_hsa041151.16099261
31Peroxisome_Homo sapiens_hsa041461.14104183
32Glutathione metabolism_Homo sapiens_hsa004801.13220696
33Alzheimers disease_Homo sapiens_hsa050101.10698712
34Other glycan degradation_Homo sapiens_hsa005111.10429878
35Histidine metabolism_Homo sapiens_hsa003401.10395338
36Arachidonic acid metabolism_Homo sapiens_hsa005901.09323124
37Propanoate metabolism_Homo sapiens_hsa006401.09264114
38Butanoate metabolism_Homo sapiens_hsa006501.08728957
39Basal transcription factors_Homo sapiens_hsa030221.08475726
40Non-homologous end-joining_Homo sapiens_hsa034501.07404321
41RNA degradation_Homo sapiens_hsa030181.03114837
42Huntingtons disease_Homo sapiens_hsa050161.02739401
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.01929652
44Selenocompound metabolism_Homo sapiens_hsa004500.99532941
45Linoleic acid metabolism_Homo sapiens_hsa005910.98158040
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96179991
47Pyruvate metabolism_Homo sapiens_hsa006200.96109910
48Fat digestion and absorption_Homo sapiens_hsa049750.94624342
49Lysosome_Homo sapiens_hsa041420.92917410
50Metabolic pathways_Homo sapiens_hsa011000.89762752
51Collecting duct acid secretion_Homo sapiens_hsa049660.88656829
52Ether lipid metabolism_Homo sapiens_hsa005650.87362461
53RNA transport_Homo sapiens_hsa030130.87153046
54Hippo signaling pathway_Homo sapiens_hsa043900.86836912
55ECM-receptor interaction_Homo sapiens_hsa045120.86077452
56Pyrimidine metabolism_Homo sapiens_hsa002400.85217387
57Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.83253284
58Purine metabolism_Homo sapiens_hsa002300.83135788
59Phagosome_Homo sapiens_hsa041450.82547729
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81699600
61Mineral absorption_Homo sapiens_hsa049780.80605045
622-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80402926
63Cysteine and methionine metabolism_Homo sapiens_hsa002700.79667699
64One carbon pool by folate_Homo sapiens_hsa006700.79625828
65alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.78877372
66Focal adhesion_Homo sapiens_hsa045100.76394348
67Pancreatic secretion_Homo sapiens_hsa049720.75948346
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74223629
69Galactose metabolism_Homo sapiens_hsa000520.73841686
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73424928
71Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.73317813
72Rheumatoid arthritis_Homo sapiens_hsa053230.72838453
73Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.72226081
74Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.70917200
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70673059
76Sulfur relay system_Homo sapiens_hsa041220.70556616
77Retinol metabolism_Homo sapiens_hsa008300.70520648
78Hedgehog signaling pathway_Homo sapiens_hsa043400.70177545
79Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.68462104
80Steroid hormone biosynthesis_Homo sapiens_hsa001400.68247767
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67704851
82Complement and coagulation cascades_Homo sapiens_hsa046100.66699796
83Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.66096399
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.65224462
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63433937
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.63228763
87Homologous recombination_Homo sapiens_hsa034400.62860423
88Mismatch repair_Homo sapiens_hsa034300.62589888
89Chemical carcinogenesis_Homo sapiens_hsa052040.61571329
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61356261
91Regulation of autophagy_Homo sapiens_hsa041400.60550801
92Renin-angiotensin system_Homo sapiens_hsa046140.59071346
93Nitrogen metabolism_Homo sapiens_hsa009100.57014657
94Circadian rhythm_Homo sapiens_hsa047100.56152552
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55818368
96Proteoglycans in cancer_Homo sapiens_hsa052050.53663159
97Ovarian steroidogenesis_Homo sapiens_hsa049130.52879869
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52796417
99Adherens junction_Homo sapiens_hsa045200.52648031
100Starch and sucrose metabolism_Homo sapiens_hsa005000.52347339
101Fatty acid metabolism_Homo sapiens_hsa012120.51711070
102PI3K-Akt signaling pathway_Homo sapiens_hsa041510.51407253
103Fructose and mannose metabolism_Homo sapiens_hsa000510.51052094
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50648165
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49508486
106Basal cell carcinoma_Homo sapiens_hsa052170.49198444
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.48356470
108TGF-beta signaling pathway_Homo sapiens_hsa043500.47356849
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47240458
110Malaria_Homo sapiens_hsa051440.45953145
111Nucleotide excision repair_Homo sapiens_hsa034200.44785110
112Fanconi anemia pathway_Homo sapiens_hsa034600.43737056
113Tryptophan metabolism_Homo sapiens_hsa003800.42810510
114Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.41631641
115Caffeine metabolism_Homo sapiens_hsa002320.40632188
116Drug metabolism - other enzymes_Homo sapiens_hsa009830.39776526
117Biosynthesis of amino acids_Homo sapiens_hsa012300.33978454
118Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.33533687
119Fatty acid degradation_Homo sapiens_hsa000710.33220902
120Tyrosine metabolism_Homo sapiens_hsa003500.32950662
121Ribosome_Homo sapiens_hsa030100.30902352
122beta-Alanine metabolism_Homo sapiens_hsa004100.30156447
123Carbon metabolism_Homo sapiens_hsa012000.30021195
124Thyroid hormone synthesis_Homo sapiens_hsa049180.28286869
125Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27003527
126Glycosaminoglycan degradation_Homo sapiens_hsa005310.26908070
127Insulin secretion_Homo sapiens_hsa049110.26718725
128Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.26221242

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