YLPM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)4.11913244
2nuclear pore complex assembly (GO:0051292)4.07024362
3locomotory exploration behavior (GO:0035641)4.04380366
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.95212651
5regulation of RNA export from nucleus (GO:0046831)3.91052523
6negative regulation of histone methylation (GO:0031061)3.85842654
7vocalization behavior (GO:0071625)3.83895115
8ionotropic glutamate receptor signaling pathway (GO:0035235)3.82099066
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.79685285
10histone H3-K4 trimethylation (GO:0080182)3.76238103
11glucocorticoid receptor signaling pathway (GO:0042921)3.73437393
12protein-DNA complex disassembly (GO:0032986)3.62295222
13nucleosome disassembly (GO:0006337)3.62295222
14neuron cell-cell adhesion (GO:0007158)3.61259189
15regulation of glutamate receptor signaling pathway (GO:1900449)3.56239567
16regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.54286160
17glutamate receptor signaling pathway (GO:0007215)3.51014612
18positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.50282628
19histone H3-K36 demethylation (GO:0070544)3.45222108
20mitotic sister chromatid cohesion (GO:0007064)3.43021077
21regulation of NFAT protein import into nucleus (GO:0051532)3.42271661
22nuclear pore organization (GO:0006999)3.39524215
23protein localization to synapse (GO:0035418)3.37518539
24axonal fasciculation (GO:0007413)3.34974829
25cerebellar Purkinje cell differentiation (GO:0021702)3.33364081
26dendritic spine morphogenesis (GO:0060997)3.29978773
27neuron recognition (GO:0008038)3.28393070
28regulation of nucleobase-containing compound transport (GO:0032239)3.28037792
29exploration behavior (GO:0035640)3.25908113
30layer formation in cerebral cortex (GO:0021819)3.25671357
31synaptic vesicle maturation (GO:0016188)3.25425169
32embryonic retina morphogenesis in camera-type eye (GO:0060059)3.24495394
33presynaptic membrane assembly (GO:0097105)3.22235289
34synaptic transmission, glutamatergic (GO:0035249)3.18043498
35pre-miRNA processing (GO:0031054)3.17464238
36cytoplasmic mRNA processing body assembly (GO:0033962)3.13938807
37heterochromatin organization (GO:0070828)3.07041588
38regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.05705205
39histone H3-K9 methylation (GO:0051567)3.03453034
40histone H3-K9 demethylation (GO:0033169)3.03079916
41negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.02504328
42negative regulation of translation, ncRNA-mediated (GO:0040033)3.02504328
43regulation of translation, ncRNA-mediated (GO:0045974)3.02504328
44positive regulation of dendritic spine morphogenesis (GO:0061003)3.00822247
45central nervous system projection neuron axonogenesis (GO:0021952)3.00667235
46presynaptic membrane organization (GO:0097090)3.00142881
47corticosteroid receptor signaling pathway (GO:0031958)2.96986963
48synaptic vesicle endocytosis (GO:0048488)2.96918144
49mRNA splice site selection (GO:0006376)2.96459975
50synaptic vesicle exocytosis (GO:0016079)2.95890553
51regulation of DNA endoreduplication (GO:0032875)2.94985385
52neuron-neuron synaptic transmission (GO:0007270)2.93907413
53G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.93772890
54RNA localization (GO:0006403)2.91126797
55chromosome condensation (GO:0030261)2.90856621
56chromatin silencing (GO:0006342)2.89682943
57histone H3-K4 methylation (GO:0051568)2.89525146
58regulation of dendritic spine morphogenesis (GO:0061001)2.88998321
59stress granule assembly (GO:0034063)2.88937071
60positive regulation of gene expression, epigenetic (GO:0045815)2.88488613
61NLS-bearing protein import into nucleus (GO:0006607)2.86949560
62mitotic chromosome condensation (GO:0007076)2.86513044
63regulation of long-term neuronal synaptic plasticity (GO:0048169)2.85068774
64synaptic vesicle docking involved in exocytosis (GO:0016081)2.83336496
65establishment of nucleus localization (GO:0040023)2.81359331
66regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.80043382
67cell migration in hindbrain (GO:0021535)2.79234694
68regulation of excitatory postsynaptic membrane potential (GO:0060079)2.78823121
69generation of neurons (GO:0048699)2.78401305
70dendrite morphogenesis (GO:0048813)2.78282158
71regulation of postsynaptic membrane potential (GO:0060078)2.77212799
72glutamate secretion (GO:0014047)2.76814118
73monoubiquitinated protein deubiquitination (GO:0035520)2.76021940
74positive regulation of synapse maturation (GO:0090129)2.75900303
75establishment of protein localization to Golgi (GO:0072600)2.75230564
76transmission of nerve impulse (GO:0019226)2.74590017
77pore complex assembly (GO:0046931)2.74101278
78regulation of neuronal synaptic plasticity (GO:0048168)2.73718458
79histone lysine demethylation (GO:0070076)2.73502947
80DNA packaging (GO:0006323)2.70297867
81long-term memory (GO:0007616)2.70153676
82postsynaptic membrane organization (GO:0001941)2.69820089
83peptidyl-lysine dimethylation (GO:0018027)2.69802629
84peptidyl-lysine trimethylation (GO:0018023)2.68426352
85paraxial mesoderm development (GO:0048339)2.67660202
86histone H3-K9 modification (GO:0061647)2.65899307
87regulation of histone H3-K27 methylation (GO:0061085)2.65535147
88establishment of spindle orientation (GO:0051294)2.65381560
89establishment of spindle localization (GO:0051293)2.64859489
90regulation of centriole replication (GO:0046599)2.64581389
91behavioral fear response (GO:0001662)2.63762325
92behavioral defense response (GO:0002209)2.63762325
93histone demethylation (GO:0016577)2.62952091
94positive regulation by host of viral transcription (GO:0043923)2.61526197
95regulation of histone methylation (GO:0031060)2.59798851
96embryonic camera-type eye morphogenesis (GO:0048596)2.59620878
97DNA unwinding involved in DNA replication (GO:0006268)2.59488779
98regulation of synaptic vesicle exocytosis (GO:2000300)2.57685117
99positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.56404082
100regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.56404082
101negative regulation of gene expression, epigenetic (GO:0045814)2.56049710
102peptidyl-lysine methylation (GO:0018022)2.56008819
103gamma-aminobutyric acid signaling pathway (GO:0007214)2.55778689
104camera-type eye morphogenesis (GO:0048593)2.54329440
105cerebellar granule cell differentiation (GO:0021707)2.53551998
106response to histamine (GO:0034776)2.53545653
107negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.53106933
108planar cell polarity pathway involved in neural tube closure (GO:0090179)2.52620884
109histone methylation (GO:0016571)2.52265231
110insulin-like growth factor receptor signaling pathway (GO:0048009)2.51045107
111neuronal ion channel clustering (GO:0045161)2.50658122
112cell differentiation in hindbrain (GO:0021533)2.48129289
113coronary vasculature morphogenesis (GO:0060977)2.48111456
114membrane depolarization during action potential (GO:0086010)2.47888376
115regulation of posttranscriptional gene silencing (GO:0060147)2.47854366
116regulation of gene silencing by miRNA (GO:0060964)2.47854366
117regulation of gene silencing by RNA (GO:0060966)2.47854366
118positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.47557362
119head development (GO:0060322)2.46400963
120DNA topological change (GO:0006265)2.46104246
121neural tube development (GO:0021915)2.45585586
122histone H4-K16 acetylation (GO:0043984)2.45325360
123negative regulation of histone modification (GO:0031057)2.45268842
124innervation (GO:0060384)2.44914315
125membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.44865306
126histone lysine methylation (GO:0034968)2.44839292
127fear response (GO:0042596)2.44133951
128sister chromatid segregation (GO:0000819)2.43374610
129regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.43303840
130interkinetic nuclear migration (GO:0022027)2.42567326
131neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.40999392
132cochlea development (GO:0090102)2.40501029
133regulation of histone H3-K9 methylation (GO:0051570)2.40412271
134vesicle transport along microtubule (GO:0047496)2.40102237
135startle response (GO:0001964)2.40023077
136neurotransmitter secretion (GO:0007269)2.39470085
137membrane hyperpolarization (GO:0060081)2.38746591
138retrograde transport, vesicle recycling within Golgi (GO:0000301)2.38710289
139ventricular system development (GO:0021591)2.38359070
140regulation of synaptic plasticity (GO:0048167)2.37805940
141positive regulation of dendrite morphogenesis (GO:0050775)2.37640831
142regulation of dendritic spine development (GO:0060998)2.37173971
143regulation of histone H3-K4 methylation (GO:0051569)2.37151667
144nerve growth factor signaling pathway (GO:0038180)2.37065566
145long-term synaptic potentiation (GO:0060291)2.36388673
146dendritic spine organization (GO:0097061)2.36296475
147regulation of synaptic transmission, glutamatergic (GO:0051966)2.36248127
148regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.35974440
149positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.35974440
150G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.35928223
151V(D)J recombination (GO:0033151)2.35053778
152sister chromatid cohesion (GO:0007062)2.34977573
153membrane depolarization (GO:0051899)2.34865675
154positive regulation of dendritic spine development (GO:0060999)2.34797311
155spliceosomal tri-snRNP complex assembly (GO:0000244)2.34583727
156protein targeting to Golgi (GO:0000042)2.34268182
157gamma-aminobutyric acid transport (GO:0015812)2.34262959
158histone H4 acetylation (GO:0043967)2.34010757
159RNA stabilization (GO:0043489)2.33826685
160mRNA stabilization (GO:0048255)2.33826685
161nucleus organization (GO:0006997)2.33687349
162neuronal stem cell maintenance (GO:0097150)2.33628458
163protein dealkylation (GO:0008214)2.33369375
164protein demethylation (GO:0006482)2.33369375
165negative regulation of DNA repair (GO:0045738)2.32117711
166central nervous system neuron axonogenesis (GO:0021955)2.31839006
167synapse assembly (GO:0007416)2.31142351
168histone deubiquitination (GO:0016578)2.29818358
169suckling behavior (GO:0001967)2.29236673
170nucleus localization (GO:0051647)2.28300572
171inner ear receptor cell development (GO:0060119)2.28278329
172organelle transport along microtubule (GO:0072384)2.27756357
173intracellular estrogen receptor signaling pathway (GO:0030520)2.26180500
174establishment of mitotic spindle localization (GO:0040001)2.25912235
175negative regulation of chromatin modification (GO:1903309)2.24431354
176peptidyl-threonine phosphorylation (GO:0018107)2.24235338
177positive regulation of RNA splicing (GO:0033120)2.23972762
178DNA conformation change (GO:0071103)2.23964788
179heart morphogenesis (GO:0003007)2.20900316
180DNA duplex unwinding (GO:0032508)2.19899026

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.50771340
2E2F7_22180533_ChIP-Seq_HELA_Human3.75054922
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.56013541
4ZFP322A_24550733_ChIP-Seq_MESCs_Mouse3.44306350
5GBX2_23144817_ChIP-Seq_PC3_Human3.42011342
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.60725014
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.42649908
8DROSHA_22980978_ChIP-Seq_HELA_Human2.23954140
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.20860917
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.19712515
11SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.09999671
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.04181740
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.03211069
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.03211069
15RARB_27405468_Chip-Seq_BRAIN_Mouse2.02070487
16REST_21632747_ChIP-Seq_MESCs_Mouse1.96664864
17RBPJ_22232070_ChIP-Seq_NCS_Mouse1.88439315
18RNF2_27304074_Chip-Seq_ESCs_Mouse1.86940027
19AR_21572438_ChIP-Seq_LNCaP_Human1.86444049
20EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.85271470
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.84766631
22JARID2_20075857_ChIP-Seq_MESCs_Mouse1.84571586
23MYC_22102868_ChIP-Seq_BL_Human1.78448678
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.76669988
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.75719477
26PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.74556322
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.73281524
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.73148971
29SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.71207843
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69362160
31* SMAD4_21799915_ChIP-Seq_A2780_Human1.67808951
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.67392065
33EGR1_19374776_ChIP-ChIP_THP-1_Human1.66693048
34RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.66301212
35EED_16625203_ChIP-ChIP_MESCs_Mouse1.66162775
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.64483536
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.64461150
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64030590
39FUS_26573619_Chip-Seq_HEK293_Human1.63966490
40TP53_16413492_ChIP-PET_HCT116_Human1.63349635
41SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.61441748
42TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60082393
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.60082393
44TAF15_26573619_Chip-Seq_HEK293_Human1.57672311
45EZH2_27294783_Chip-Seq_ESCs_Mouse1.53638021
46PKCTHETA_26484144_Chip-Seq_BREAST_Human1.53551784
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.51987040
48NFIB_24661679_ChIP-Seq_LUNG_Mouse1.51772192
49STAT3_23295773_ChIP-Seq_U87_Human1.50313680
50SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49320997
51* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.46727453
52KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.44871908
53TCF4_23295773_ChIP-Seq_U87_Human1.41731179
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.41166208
55AR_19668381_ChIP-Seq_PC3_Human1.41108030
56VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.40875187
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.40573391
58YAP1_20516196_ChIP-Seq_MESCs_Mouse1.38454971
59* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.38035903
60SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.37646008
61P300_19829295_ChIP-Seq_ESCs_Human1.36746026
62CBX2_27304074_Chip-Seq_ESCs_Mouse1.36573726
63WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.36332427
64ZNF274_21170338_ChIP-Seq_K562_Hela1.35420330
65ARNT_22903824_ChIP-Seq_MCF-7_Human1.35357739
66NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.34645556
67ZNF217_24962896_ChIP-Seq_MCF-7_Human1.34469621
68HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.34024778
69SOX2_21211035_ChIP-Seq_LN229_Gbm1.33637352
70DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.32064752
71REST_18959480_ChIP-ChIP_MESCs_Mouse1.31659304
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.30716280
73SALL1_21062744_ChIP-ChIP_HESCs_Human1.30639011
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29820733
75* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29505924
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29213147
77WT1_25993318_ChIP-Seq_PODOCYTE_Human1.27929425
78KDM2B_26808549_Chip-Seq_JURKAT_Human1.27768866
79AHR_22903824_ChIP-Seq_MCF-7_Human1.27037604
80STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.26996521
81E2F4_17652178_ChIP-ChIP_JURKAT_Human1.26724788
82BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.26075516
83RING1B_27294783_Chip-Seq_NPCs_Mouse1.26062032
84KDM2B_26808549_Chip-Seq_K562_Human1.25862595
85POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25597225
86E2F1_21310950_ChIP-Seq_MCF-7_Human1.25436260
87ZFP281_27345836_Chip-Seq_ESCs_Mouse1.25324245
88RNF2_27304074_Chip-Seq_NSC_Mouse1.24860376
89ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23907627
90CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.23592707
91RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22813314
92* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.21673007
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21574058
94EWS_26573619_Chip-Seq_HEK293_Human1.20702803
95PIAS1_25552417_ChIP-Seq_VCAP_Human1.20438285
96TCF7_22412390_ChIP-Seq_EML_Mouse1.20088337
97SOX9_24532713_ChIP-Seq_HFSC_Mouse1.19290597
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19121980
99WT1_19549856_ChIP-ChIP_CCG9911_Human1.16884006
100TBX3_20139965_ChIP-Seq_MESCs_Mouse1.16685131
101OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16576286
102TBX3_20139965_ChIP-Seq_ESCs_Mouse1.16114758
103RING1B_27294783_Chip-Seq_ESCs_Mouse1.15025224
104KDM2B_26808549_Chip-Seq_DND41_Human1.13794754
105GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13672132
106ISL1_27105846_Chip-Seq_CPCs_Mouse1.13228785
107GATA1_26923725_Chip-Seq_HPCs_Mouse1.12043610
108AR_25329375_ChIP-Seq_VCAP_Human1.10997239
109CTNNB1_20460455_ChIP-Seq_HCT116_Human1.10550170
110TP63_19390658_ChIP-ChIP_HaCaT_Human1.10377456
111* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10213540
112SOX9_26525672_Chip-Seq_HEART_Mouse1.09859782
113FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.09580943
114BMI1_23680149_ChIP-Seq_NPCS_Mouse1.09144597
115EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.09122983
116PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.08656923
117P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08632569
118IGF1R_20145208_ChIP-Seq_DFB_Human1.08513141
119TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08316979
120KDM2B_26808549_Chip-Seq_SUP-B15_Human1.07143518
121NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06818556
122MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.06328805
123WDR5_24793694_ChIP-Seq_LNCAP_Human1.05936303
124CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.05891088
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05145809
126SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05064237
127* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.03964741
128NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03296956
129SMAD3_21741376_ChIP-Seq_ESCs_Human1.01574706
130MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01227940
131AR_21909140_ChIP-Seq_LNCAP_Human0.98536267
132* FOXA2_19822575_ChIP-Seq_HepG2_Human0.97516000
133KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.96791124
134ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.96094809
135TCF4_18268006_ChIP-ChIP_LS174T_Human0.95879820
136POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.95457826
137OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.95366016
138MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95190589
139GF1B_26923725_Chip-Seq_HPCs_Mouse0.93343538
140LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91629633

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.71670144
2MP0003880_abnormal_central_pattern3.35681601
3MP0003635_abnormal_synaptic_transmissio3.02199906
4MP0003787_abnormal_imprinting2.75802253
5MP0000569_abnormal_digit_pigmentation2.73959800
6MP0002063_abnormal_learning/memory/cond2.43469897
7MP0009745_abnormal_behavioral_response2.35290580
8MP0004270_analgesia2.31728965
9MP0005423_abnormal_somatic_nervous2.27068070
10MP0003122_maternal_imprinting2.26416638
11MP0000778_abnormal_nervous_system2.17773143
12MP0009046_muscle_twitch2.17723459
13MP0002064_seizures2.16450039
14MP0001486_abnormal_startle_reflex2.15311285
15MP0002009_preneoplasia2.12307029
16MP0002572_abnormal_emotion/affect_behav2.11828721
17MP0003121_genomic_imprinting1.99372388
18MP0003705_abnormal_hypodermis_morpholog1.96340716
19MP0008877_abnormal_DNA_methylation1.85546290
20MP0000566_synostosis1.84051581
21MP0002272_abnormal_nervous_system1.75643578
22MP0001968_abnormal_touch/_nociception1.63081708
23MP0001440_abnormal_grooming_behavior1.62963194
24MP0003111_abnormal_nucleus_morphology1.61720464
25MP0002184_abnormal_innervation1.53918617
26MP0009780_abnormal_chondrocyte_physiolo1.52800359
27MP0009672_abnormal_birth_weight1.51259900
28MP0002067_abnormal_sensory_capabilities1.50094235
29MP0003077_abnormal_cell_cycle1.46877504
30MP0002734_abnormal_mechanical_nocicepti1.44390806
31MP0005623_abnormal_meninges_morphology1.43242590
32MP0001730_embryonic_growth_arrest1.43006052
33MP0006292_abnormal_olfactory_placode1.42537037
34MP0001348_abnormal_lacrimal_gland1.42527724
35MP0010094_abnormal_chromosome_stability1.42011391
36MP0001501_abnormal_sleep_pattern1.41521399
37MP0002735_abnormal_chemical_nociception1.41429585
38MP0004197_abnormal_fetal_growth/weight/1.40847724
39MP0000955_abnormal_spinal_cord1.39566462
40MP0002085_abnormal_embryonic_tissue1.38975034
41MP0003123_paternal_imprinting1.37574020
42MP0008569_lethality_at_weaning1.36468070
43MP0001188_hyperpigmentation1.36228267
44MP0002557_abnormal_social/conspecific_i1.35825602
45MP0005646_abnormal_pituitary_gland1.35283818
46MP0008961_abnormal_basal_metabolism1.34214999
47MP0003984_embryonic_growth_retardation1.33098932
48MP0002152_abnormal_brain_morphology1.33016303
49MP0005380_embryogenesis_phenotype1.32899213
50MP0001672_abnormal_embryogenesis/_devel1.32899213
51MP0004811_abnormal_neuron_physiology1.31649248
52MP0005409_darkened_coat_color1.31522729
53MP0002882_abnormal_neuron_morphology1.31289003
54MP0000631_abnormal_neuroendocrine_gland1.30948403
55MP0002697_abnormal_eye_size1.30408831
56MP0004885_abnormal_endolymph1.30333587
57MP0004924_abnormal_behavior1.29857063
58MP0005386_behavior/neurological_phenoty1.29857063
59MP0003861_abnormal_nervous_system1.29519988
60MP0002088_abnormal_embryonic_growth/wei1.28659471
61MP0001299_abnormal_eye_distance/1.20576477
62MP0002733_abnormal_thermal_nociception1.19329606
63MP0001286_abnormal_eye_development1.18300198
64MP0004145_abnormal_muscle_electrophysio1.18107360
65MP0003693_abnormal_embryo_hatching1.17626792
66MP0003890_abnormal_embryonic-extraembry1.15286247
67MP0000350_abnormal_cell_proliferation1.14354456
68MP0002736_abnormal_nociception_after1.12516620
69MP0003385_abnormal_body_wall1.11645080
70MP0005551_abnormal_eye_electrophysiolog1.10600883
71MP0005187_abnormal_penis_morphology1.10549444
72MP0002092_abnormal_eye_morphology1.10094396
73MP0003091_abnormal_cell_migration1.07242160
74MP0009053_abnormal_anal_canal1.05189897
75MP0001177_atelectasis1.05073962
76MP0001970_abnormal_pain_threshold1.04854590
77MP0008057_abnormal_DNA_replication1.03415586
78MP0002396_abnormal_hematopoietic_system1.03230932
79MP0005645_abnormal_hypothalamus_physiol1.02849165
80MP0010307_abnormal_tumor_latency1.02678895
81MP0000733_abnormal_muscle_development1.02611339
82MP0000049_abnormal_middle_ear1.02090605
83MP0004808_abnormal_hematopoietic_stem1.02028909
84MP0010352_gastrointestinal_tract_polyps1.00973686
85MP0001697_abnormal_embryo_size1.00848835
86MP0006072_abnormal_retinal_apoptosis1.00815392
87MP0002066_abnormal_motor_capabilities/c1.00716493
88MP0002925_abnormal_cardiovascular_devel0.99085740
89MP0003315_abnormal_perineum_morphology0.98857449
90MP0002822_catalepsy0.98515156
91MP0000537_abnormal_urethra_morphology0.98313543
92MP0003935_abnormal_craniofacial_develop0.97930116
93MP0010368_abnormal_lymphatic_system0.97244957
94MP0002909_abnormal_adrenal_gland0.96985203
95MP0005499_abnormal_olfactory_system0.96751517
96MP0005394_taste/olfaction_phenotype0.96751517
97MP0001879_abnormal_lymphatic_vessel0.96382774
98MP0004233_abnormal_muscle_weight0.95784760
99MP0002086_abnormal_extraembryonic_tissu0.95307239
100MP0006276_abnormal_autonomic_nervous0.94904000
101MP0001346_abnormal_lacrimal_gland0.93626010
102MP0003938_abnormal_ear_development0.93214695
103MP0001293_anophthalmia0.92748491
104MP0010030_abnormal_orbit_morphology0.92148333
105MP0003937_abnormal_limbs/digits/tail_de0.92005146
106MP0003943_abnormal_hepatobiliary_system0.91057724
107MP0005076_abnormal_cell_differentiation0.90029958
108MP0004957_abnormal_blastocyst_morpholog0.89976666
109MP0002080_prenatal_lethality0.89781812
110MP0002089_abnormal_postnatal_growth/wei0.89751425
111MP0009703_decreased_birth_body0.89503681
112MP0004185_abnormal_adipocyte_glucose0.88852805
113MP0003283_abnormal_digestive_organ0.88024535
114MP0001502_abnormal_circadian_rhythm0.87793724
115MP0002108_abnormal_muscle_morphology0.87119640
116MP0002234_abnormal_pharynx_morphology0.86782778
117MP0002116_abnormal_craniofacial_bone0.86310827
118MP0000579_abnormal_nail_morphology0.85321507
119MP0002081_perinatal_lethality0.84871914
120MP0002752_abnormal_somatic_nervous0.84320247
121MP0003755_abnormal_palate_morphology0.83892976
122MP0004085_abnormal_heartbeat0.83618490
123MP0000534_abnormal_ureter_morphology0.83326889
124MP0001270_distended_abdomen0.81404638
125MP0003045_fibrosis0.81284237
126MP0003119_abnormal_digestive_system0.80616398
127MP0003115_abnormal_respiratory_system0.79519549
128MP0002084_abnormal_developmental_patter0.78873435
129MP0004134_abnormal_chest_morphology0.78657876
130MP0000428_abnormal_craniofacial_morphol0.78197285
131MP0004742_abnormal_vestibular_system0.77804518
132MP0003698_abnormal_male_reproductive0.77100535
133MP0004858_abnormal_nervous_system0.76399915
134MP0001984_abnormal_olfaction0.76131337
135MP0000751_myopathy0.76064740
136MP0010769_abnormal_survival0.74194647
137MP0010770_preweaning_lethality0.73932983
138MP0002082_postnatal_lethality0.73932983
139MP0003942_abnormal_urinary_system0.73586005
140MP0002249_abnormal_larynx_morphology0.72751649
141MP0003632_abnormal_nervous_system0.72636077
142MP0001943_abnormal_respiration0.72591295
143MP0002114_abnormal_axial_skeleton0.72254652
144MP0010768_mortality/aging0.71863243
145MP0000432_abnormal_head_morphology0.71330903
146MP0002233_abnormal_nose_morphology0.70656065

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)3.80121393
2Focal seizures (HP:0007359)3.23093681
3Genetic anticipation (HP:0003743)3.03772510
4Macroorchidism (HP:0000053)2.94932095
5Epileptic encephalopathy (HP:0200134)2.93796764
6Volvulus (HP:0002580)2.93350801
7Broad-based gait (HP:0002136)2.89879160
8Progressive cerebellar ataxia (HP:0002073)2.75070531
9Abnormality of the fingertips (HP:0001211)2.63754848
10Excessive salivation (HP:0003781)2.62698484
11Drooling (HP:0002307)2.62698484
12Febrile seizures (HP:0002373)2.59716601
13Gaze-evoked nystagmus (HP:0000640)2.55061061
14Trigonocephaly (HP:0000243)2.38111930
15Hepatoblastoma (HP:0002884)2.36460504
16Obsessive-compulsive behavior (HP:0000722)2.36053625
17Urethral obstruction (HP:0000796)2.34995129
18Broad face (HP:0000283)2.34468403
19Vertebral arch anomaly (HP:0008438)2.31178878
20Urinary bladder sphincter dysfunction (HP:0002839)2.29922632
21Absent speech (HP:0001344)2.27895230
22Atonic seizures (HP:0010819)2.27758902
23Short 4th metacarpal (HP:0010044)2.26376598
24Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.26376598
25High anterior hairline (HP:0009890)2.25820354
26Visual hallucinations (HP:0002367)2.25027773
27Protruding tongue (HP:0010808)2.24794622
28Abnormality of the distal phalanx of the thumb (HP:0009617)2.24772238
29Truncal ataxia (HP:0002078)2.18576572
30Abnormality of the nasal septum (HP:0000419)2.18562052
31Abnormality of the phalanges of the hallux (HP:0010057)2.17785222
32Long eyelashes (HP:0000527)2.17014858
33Myokymia (HP:0002411)2.16830338
34Abnormality of the aortic arch (HP:0012303)2.13027362
35Action tremor (HP:0002345)2.12363245
36Supernumerary ribs (HP:0005815)2.11850343
37Heterotopia (HP:0002282)2.11168480
38Midline defect of the nose (HP:0004122)2.11095867
39Narrow palate (HP:0000189)2.10998330
40Dysdiadochokinesis (HP:0002075)2.10475120
41Abnormality of the lower motor neuron (HP:0002366)2.08481206
42Impaired smooth pursuit (HP:0007772)2.08363286
43Dysmetric saccades (HP:0000641)2.05494920
44Bronchomalacia (HP:0002780)2.03953387
45Abnormality of the ischium (HP:0003174)2.03574628
46Absence seizures (HP:0002121)2.03369224
47Impaired vibration sensation in the lower limbs (HP:0002166)2.01136840
48Increased nuchal translucency (HP:0010880)2.00348666
49Abnormality of ocular smooth pursuit (HP:0000617)1.99796338
50Aqueductal stenosis (HP:0002410)1.99628257
51Astrocytoma (HP:0009592)1.98261965
52Abnormality of the astrocytes (HP:0100707)1.98261965
53Hypoplastic ischia (HP:0003175)1.97057782
54Thick eyebrow (HP:0000574)1.96449266
55Hyperventilation (HP:0002883)1.95379833
56Poor eye contact (HP:0000817)1.94215941
57Ectopic kidney (HP:0000086)1.93629208
58Inappropriate behavior (HP:0000719)1.92056393
59Abnormality of the columella (HP:0009929)1.91754464
60Abnormality of the labia minora (HP:0012880)1.90981994
61Abnormality of the corticospinal tract (HP:0002492)1.90172318
62Hyperacusis (HP:0010780)1.87532872
63Dialeptic seizures (HP:0011146)1.87480692
64Gastroesophageal reflux (HP:0002020)1.87365275
65Tracheomalacia (HP:0002779)1.87192326
66Termporal pattern (HP:0011008)1.86660998
67Insidious onset (HP:0003587)1.86660998
68Obstructive sleep apnea (HP:0002870)1.86264306
69Supernumerary bones of the axial skeleton (HP:0009144)1.86151094
70Impaired social interactions (HP:0000735)1.86147888
71Abnormal social behavior (HP:0012433)1.86147888
72Insomnia (HP:0100785)1.85987794
73Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.85381599
74Abnormal number of incisors (HP:0011064)1.85263036
75Broad phalanges of the hand (HP:0009768)1.83347341
76Pointed chin (HP:0000307)1.82667640
77Widely spaced teeth (HP:0000687)1.82612747
78Prominent nose (HP:0000448)1.82581520
79Sandal gap (HP:0001852)1.82561974
80Laryngomalacia (HP:0001601)1.82285696
81Exotropia (HP:0000577)1.81786873
82Broad finger (HP:0001500)1.81347259
83Truncal obesity (HP:0001956)1.80423128
84Spina bifida occulta (HP:0003298)1.80359354
85Open mouth (HP:0000194)1.80323154
86Absent frontal sinuses (HP:0002688)1.79785048
87Autism (HP:0000717)1.79433835
88Elfin facies (HP:0004428)1.79272275
89Sacral dimple (HP:0000960)1.79036655
90Overgrowth (HP:0001548)1.78063864
91Attention deficit hyperactivity disorder (HP:0007018)1.77325069
92Anal stenosis (HP:0002025)1.76616489
93Deep palmar crease (HP:0006191)1.75511170
94Radioulnar synostosis (HP:0002974)1.75094909
95Neoplasm of the oral cavity (HP:0100649)1.73359528
96Dysmetria (HP:0001310)1.72887949
97Hypoplasia of the maxilla (HP:0000327)1.72081402
98Smooth philtrum (HP:0000319)1.71391490
99Renovascular hypertension (HP:0100817)1.70588285
100Cutaneous finger syndactyly (HP:0010554)1.70444288
101Dislocated radial head (HP:0003083)1.69717879
102Neoplasm of the heart (HP:0100544)1.69091143
103Cubitus valgus (HP:0002967)1.68917819
104Overriding aorta (HP:0002623)1.68818927
105Patellar dislocation (HP:0002999)1.68332121
106Glioma (HP:0009733)1.68262038
107Abnormality of the incisor (HP:0000676)1.67147201
108Papillary thyroid carcinoma (HP:0002895)1.66749657
109Stereotypic behavior (HP:0000733)1.66253405
110Partial agenesis of the corpus callosum (HP:0001338)1.65979775
111Renal duplication (HP:0000075)1.65929784
112Aplasia/Hypoplasia of the sternum (HP:0006714)1.65825559
113Arnold-Chiari malformation (HP:0002308)1.65351223
114Broad long bones (HP:0005622)1.65129171
115Tapered finger (HP:0001182)1.64955552
116Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.64716607
117Turricephaly (HP:0000262)1.64713091
118Precocious puberty (HP:0000826)1.64347958
119Omphalocele (HP:0001539)1.64180360
120Broad phalanx (HP:0006009)1.64127256
121Abnormality of the antihelix (HP:0009738)1.64061397
122Impulsivity (HP:0100710)1.63880952
123Abnormality of the radial head (HP:0003995)1.63796166
124Abnormality of the 4th metacarpal (HP:0010012)1.63399577
125Acute myeloid leukemia (HP:0004808)1.63176723
126Shallow orbits (HP:0000586)1.62955572
127Abnormal hair whorl (HP:0010721)1.62562831
128Patellar aplasia (HP:0006443)1.62458535
129Absent/shortened dynein arms (HP:0200106)1.62355656
130Dynein arm defect of respiratory motile cilia (HP:0012255)1.62355656
131Shawl scrotum (HP:0000049)1.62193773
132Hypopigmentation of the fundus (HP:0007894)1.62010896
133Wide anterior fontanel (HP:0000260)1.61682094
134Synophrys (HP:0000664)1.61455546
135Chromsome breakage (HP:0040012)1.60453192
136Chin dimple (HP:0010751)1.60333442
137Amblyopia (HP:0000646)1.60128334
138Urinary urgency (HP:0000012)1.59943506
139Hemiparesis (HP:0001269)1.59436384
140Broad thumb (HP:0011304)1.59144679
141Tented upper lip vermilion (HP:0010804)1.59132194
142Acute lymphatic leukemia (HP:0006721)1.59110698
143Neonatal short-limb short stature (HP:0008921)1.58846403
144Deeply set eye (HP:0000490)1.57999553
145Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.57986968
146Degeneration of the lateral corticospinal tracts (HP:0002314)1.57986968
147Amyotrophic lateral sclerosis (HP:0007354)1.57892475
148Abnormality of chromosome segregation (HP:0002916)1.57771224
149Abnormality of salivation (HP:0100755)1.57437264
150Low anterior hairline (HP:0000294)1.57394492
151Abnormality of the parietal bone (HP:0002696)1.55519737
152Scanning speech (HP:0002168)1.54935554
153Abnormality of the epiphyses of the hand (HP:0005924)1.53699421
154Cutaneous syndactyly (HP:0012725)1.52706999
155Broad hallux (HP:0010055)1.51099861
156Skull defect (HP:0001362)1.50677765

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.14289015
2NTRK33.85631065
3BRD43.83145023
4PNCK3.51523645
5CAMK1G2.98218696
6EPHA42.94607132
7SIK22.39483018
8MAP3K42.37790235
9MARK12.35767599
10TRIB32.22158596
11NTRK21.97984249
12CAMK1D1.95383019
13MAP3K91.85447775
14PRKD31.56366591
15CASK1.55772398
16MAPK131.55753854
17MINK11.49225434
18ICK1.48479107
19NEK21.42213980
20MARK21.33173177
21LATS11.30421287
22PLK41.30276340
23CDC71.28485105
24PAK61.22016730
25MAP2K71.19776749
26KSR11.18513998
27MKNK21.18187523
28TNIK1.17560617
29EEF2K1.12277675
30WNK11.10366837
31PKN21.10365954
32SGK21.09032180
33TYRO31.08941134
34DAPK21.06796801
35ALK1.03809018
36STK111.01831477
37PLK21.01122143
38CDK50.98862401
39DMPK0.98723731
40SGK30.98452144
41SMG10.97473557
42UHMK10.96508024
43PRPF4B0.94962617
44CDC42BPA0.94418770
45FGFR20.94400809
46CAMK10.93443591
47CDK70.90275056
48SGK10.89488274
49FES0.89098178
50STK380.88591899
51PRKD20.88438864
52CDK40.87776391
53NLK0.87613152
54MTOR0.85752395
55DYRK1A0.84340463
56TAOK10.84244272
57AKT30.83923361
58MAP2K40.83833955
59LATS20.83293604
60CAMK40.82234658
61MAPK100.82018923
62SIK10.81381318
63MELK0.79603435
64SGK2230.78268163
65SGK4940.78268163
66CSNK1E0.76356729
67PTK2B0.75444054
68MKNK10.72790158
69RIPK10.70988351
70FGFR30.69218733
71PAK30.67685966
72MAP3K70.67508617
73* GSK3B0.67097917
74CAMK2A0.65486065
75RIPK40.65164071
76PDGFRA0.65034875
77PRKCH0.64999884
78CHEK10.64958789
79CSNK1A1L0.64697382
80FGR0.64091577
81CAMKK10.64070264
82DAPK10.63008279
83FGFR40.62859630
84PDGFRB0.62635835
85CDK90.62339114
86RPS6KA30.61839315
87CSNK1G20.59558212
88PRKDC0.59134209
89PRKCG0.58349326
90MAPK80.57844626
91MAP3K100.57067679
92SRPK10.57020883
93* MAPK140.56700984
94CDK10.56596133
95CHEK20.55982921
96ATM0.55637077
97CDK20.54827521
98CSNK1D0.54062968
99HIPK20.53572129
100TNK20.53461014
101CDK60.53014761
102INSRR0.52858552
103NTRK10.52317295
104RET0.51773675
105TAF10.50834471
106BMPR1B0.49882156
107TTK0.49591955
108MAPK10.48694546
109CAMKK20.48420280
110AKT10.47885145
111PAK20.47493230
112PRKAA10.47363182
113MAPK90.46569655
114CAMK2B0.46218064
115EPHA30.45944897
116RPS6KB20.45554656
117DDR20.44123809
118EPHB20.43792359
119PKN10.43421873
120SIK30.42999385
121FGFR10.42152626
122ATR0.42136487
123PRKCB0.41258203
124PRKG10.40747491
125RPS6KA20.40209830
126STK38L0.39186424
127RPS6KA10.38039376
128STK30.36400241

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.13786353
2Long-term potentiation_Homo sapiens_hsa047202.43135510
3Glutamatergic synapse_Homo sapiens_hsa047242.36453315
4Circadian entrainment_Homo sapiens_hsa047132.29466243
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.19975154
6Morphine addiction_Homo sapiens_hsa050322.09632951
7Amphetamine addiction_Homo sapiens_hsa050312.07650410
8GABAergic synapse_Homo sapiens_hsa047272.00755496
9Olfactory transduction_Homo sapiens_hsa047401.97209776
10Dopaminergic synapse_Homo sapiens_hsa047281.81882207
11Salivary secretion_Homo sapiens_hsa049701.79290315
12Renin secretion_Homo sapiens_hsa049241.67182555
13Insulin secretion_Homo sapiens_hsa049111.65454540
14Taste transduction_Homo sapiens_hsa047421.64450014
15Aldosterone synthesis and secretion_Homo sapiens_hsa049251.64266437
16Long-term depression_Homo sapiens_hsa047301.60712501
17Axon guidance_Homo sapiens_hsa043601.57505741
18Cholinergic synapse_Homo sapiens_hsa047251.55771953
19Thyroid cancer_Homo sapiens_hsa052161.53565092
20Oxytocin signaling pathway_Homo sapiens_hsa049211.53251466
21Serotonergic synapse_Homo sapiens_hsa047261.50567205
22Calcium signaling pathway_Homo sapiens_hsa040201.49018233
23Synaptic vesicle cycle_Homo sapiens_hsa047211.48135355
24Gastric acid secretion_Homo sapiens_hsa049711.48089272
25Cocaine addiction_Homo sapiens_hsa050301.45274462
26Cell cycle_Homo sapiens_hsa041101.44592711
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.42072203
28Dorso-ventral axis formation_Homo sapiens_hsa043201.38507784
29Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37378535
30Type II diabetes mellitus_Homo sapiens_hsa049301.32880932
31cAMP signaling pathway_Homo sapiens_hsa040241.32474621
32GnRH signaling pathway_Homo sapiens_hsa049121.28001548
33Phosphatidylinositol signaling system_Homo sapiens_hsa040701.26593494
34Gap junction_Homo sapiens_hsa045401.25896027
35Phototransduction_Homo sapiens_hsa047441.25225272
36Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.25092283
37Glioma_Homo sapiens_hsa052141.24759663
38Estrogen signaling pathway_Homo sapiens_hsa049151.21510020
39Wnt signaling pathway_Homo sapiens_hsa043101.21091034
40Pancreatic cancer_Homo sapiens_hsa052121.19906490
41Acute myeloid leukemia_Homo sapiens_hsa052211.19844518
42Melanogenesis_Homo sapiens_hsa049161.18307167
43cGMP-PKG signaling pathway_Homo sapiens_hsa040221.17879513
44ErbB signaling pathway_Homo sapiens_hsa040121.17378680
45Thyroid hormone signaling pathway_Homo sapiens_hsa049191.13689186
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.11672987
47mRNA surveillance pathway_Homo sapiens_hsa030151.10817292
48Oocyte meiosis_Homo sapiens_hsa041141.09335814
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.08321933
50Hedgehog signaling pathway_Homo sapiens_hsa043401.07552342
51Spliceosome_Homo sapiens_hsa030401.06851626
52RNA transport_Homo sapiens_hsa030131.05729542
53Dilated cardiomyopathy_Homo sapiens_hsa054141.02920580
54FoxO signaling pathway_Homo sapiens_hsa040681.01817977
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.01119294
56MAPK signaling pathway_Homo sapiens_hsa040101.00400272
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99601640
58Basal cell carcinoma_Homo sapiens_hsa052170.98131921
59Non-homologous end-joining_Homo sapiens_hsa034500.97378489
60Lysine degradation_Homo sapiens_hsa003100.96672327
61TGF-beta signaling pathway_Homo sapiens_hsa043500.94981141
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.94093247
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93266776
64Prolactin signaling pathway_Homo sapiens_hsa049170.93072980
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.92856887
66Choline metabolism in cancer_Homo sapiens_hsa052310.92772477
67Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91280701
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.91188611
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.89450482
70mTOR signaling pathway_Homo sapiens_hsa041500.89326477
71AMPK signaling pathway_Homo sapiens_hsa041520.85786341
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.83705934
73Rap1 signaling pathway_Homo sapiens_hsa040150.82622399
74Insulin signaling pathway_Homo sapiens_hsa049100.80949217
75Small cell lung cancer_Homo sapiens_hsa052220.80826310
76Fatty acid biosynthesis_Homo sapiens_hsa000610.80233103
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78365688
78Ras signaling pathway_Homo sapiens_hsa040140.78092930
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75614976
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75106716
81Colorectal cancer_Homo sapiens_hsa052100.74636935
82Pancreatic secretion_Homo sapiens_hsa049720.74636335
83Renal cell carcinoma_Homo sapiens_hsa052110.74021671
84Glucagon signaling pathway_Homo sapiens_hsa049220.73310784
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.72904677
86Circadian rhythm_Homo sapiens_hsa047100.71315743
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.71201613
88Non-small cell lung cancer_Homo sapiens_hsa052230.70714659
89T cell receptor signaling pathway_Homo sapiens_hsa046600.70401720
90Adherens junction_Homo sapiens_hsa045200.70318697
91MicroRNAs in cancer_Homo sapiens_hsa052060.69915438
92B cell receptor signaling pathway_Homo sapiens_hsa046620.69797209
93Inositol phosphate metabolism_Homo sapiens_hsa005620.69643123
94ECM-receptor interaction_Homo sapiens_hsa045120.69533781
95Endometrial cancer_Homo sapiens_hsa052130.69019928
96Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.68074380
97Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66573510
98Thyroid hormone synthesis_Homo sapiens_hsa049180.65589707
99Hippo signaling pathway_Homo sapiens_hsa043900.64722386
100Notch signaling pathway_Homo sapiens_hsa043300.63817490
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63058639
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62410834
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60442407
104Hepatitis B_Homo sapiens_hsa051610.59794996
105DNA replication_Homo sapiens_hsa030300.59230795
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58595579
107VEGF signaling pathway_Homo sapiens_hsa043700.57276862
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57029281
109Proteoglycans in cancer_Homo sapiens_hsa052050.56149299
110Alcoholism_Homo sapiens_hsa050340.52827884
111Chronic myeloid leukemia_Homo sapiens_hsa052200.51897064
112Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51297489
113Prostate cancer_Homo sapiens_hsa052150.50358648
114Pathways in cancer_Homo sapiens_hsa052000.49102643
115Melanoma_Homo sapiens_hsa052180.49032522
116Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48863459
117Ovarian steroidogenesis_Homo sapiens_hsa049130.48826652
118Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48737596
119Tight junction_Homo sapiens_hsa045300.48354509
120Focal adhesion_Homo sapiens_hsa045100.46683946
121Cardiac muscle contraction_Homo sapiens_hsa042600.45079435
122Platelet activation_Homo sapiens_hsa046110.44721243

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