YPEL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous antigen (GO:0019883)5.39297917
2synaptic vesicle maturation (GO:0016188)5.30190533
3positive regulation by symbiont of host defense response (GO:0052509)5.05242540
4modulation by symbiont of host defense response (GO:0052031)5.05242540
5modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.05242540
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.05242540
7positive regulation by organism of defense response of other organism involved in symbiotic interact5.05242540
8modulation by symbiont of host immune response (GO:0052553)5.05242540
9neuronal action potential propagation (GO:0019227)4.87926602
10regulation of B cell receptor signaling pathway (GO:0050855)4.70048325
11detection of other organism (GO:0098543)4.61521878
12detection of bacterium (GO:0016045)4.57601648
13synaptic vesicle exocytosis (GO:0016079)4.56680501
14neutrophil activation involved in immune response (GO:0002283)4.51339090
15macrophage activation involved in immune response (GO:0002281)4.34035051
16regulation of short-term neuronal synaptic plasticity (GO:0048172)4.18512230
17glutamate secretion (GO:0014047)4.13695042
18negative regulation of lymphocyte mediated immunity (GO:0002707)4.13530125
19positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.04269620
20leukocyte aggregation (GO:0070486)4.02826765
21regulation of synaptic vesicle exocytosis (GO:2000300)4.01755220
22locomotory exploration behavior (GO:0035641)3.85636680
23regulation of synaptic vesicle transport (GO:1902803)3.82337098
24regulation of gamma-delta T cell activation (GO:0046643)3.81893305
25detection of external biotic stimulus (GO:0098581)3.80753194
26negative regulation of leukocyte mediated immunity (GO:0002704)3.78806628
27cellular response to interleukin-15 (GO:0071350)3.76505837
28neutrophil activation (GO:0042119)3.76113041
29negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.74783217
30positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.72273792
31positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.65792346
32response to peptidoglycan (GO:0032494)3.62093320
33negative regulation of erythrocyte differentiation (GO:0045647)3.61865554
34sodium ion export (GO:0071436)3.59321280
35regulation of interferon-beta biosynthetic process (GO:0045357)3.58069168
36negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.58007817
37B cell receptor signaling pathway (GO:0050853)3.51107335
38regulation of mast cell degranulation (GO:0043304)3.50928759
39respiratory burst (GO:0045730)3.47426308
40synaptic vesicle docking involved in exocytosis (GO:0016081)3.47002436
41cellular extravasation (GO:0045123)3.46484568
42response to host immune response (GO:0052572)3.45953500
43response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.45953500
44immunoglobulin mediated immune response (GO:0016064)3.44722921
45positive thymic T cell selection (GO:0045059)3.43111632
46leukocyte migration involved in inflammatory response (GO:0002523)3.38828679
47granulocyte activation (GO:0036230)3.38514309
48negative regulation of interleukin-12 production (GO:0032695)3.38034847
49regulation of myeloid leukocyte mediated immunity (GO:0002886)3.33575868
50vocalization behavior (GO:0071625)3.32301265
51detection of molecule of bacterial origin (GO:0032490)3.31827674
52microglial cell activation (GO:0001774)3.31624934
53ionotropic glutamate receptor signaling pathway (GO:0035235)3.29655468
54regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.29193510
55myeloid cell activation involved in immune response (GO:0002275)3.29186080
56regulation of T-helper 2 cell differentiation (GO:0045628)3.28814368
57negative regulation of T cell mediated immunity (GO:0002710)3.28645793
58neurotransmitter secretion (GO:0007269)3.27833499
59cellular potassium ion homeostasis (GO:0030007)3.26831626
60detection of biotic stimulus (GO:0009595)3.25997465
61protein localization to synapse (GO:0035418)3.23766256
62response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.18607118
63response to host (GO:0075136)3.18607118
64response to host defenses (GO:0052200)3.18607118
65regulation of leukocyte degranulation (GO:0043300)3.18362328
66cerebellar Purkinje cell differentiation (GO:0021702)3.18299929
67regulation of mast cell activation involved in immune response (GO:0033006)3.18055546
68activation of protein kinase A activity (GO:0034199)3.16781479
69neuromuscular process controlling posture (GO:0050884)3.15835038
70macrophage activation (GO:0042116)3.15045259
71germinal center formation (GO:0002467)3.14187113
72negative thymic T cell selection (GO:0045060)3.12057447
73regulation of synapse structural plasticity (GO:0051823)3.11346515
74positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.10438510
75negative regulation of phagocytosis (GO:0050765)3.09514358
76regulation of regulated secretory pathway (GO:1903305)3.09255566
77signal complex assembly (GO:0007172)3.07732192
78regulation of B cell differentiation (GO:0045577)3.07497165
79regulation of glutamate receptor signaling pathway (GO:1900449)3.06769760
80neutrophil mediated immunity (GO:0002446)3.05249040
81negative regulation of cell killing (GO:0031342)3.04917661
82negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.04917661
83regulation of neuronal synaptic plasticity (GO:0048168)3.04346885
84type I interferon signaling pathway (GO:0060337)3.03948687
85cellular response to type I interferon (GO:0071357)3.03948687
86positive regulation of mast cell activation (GO:0033005)3.03227287
87positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.03169793
88response to type I interferon (GO:0034340)3.03140515
89regulation of T cell tolerance induction (GO:0002664)3.01696301
90G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.01679037
91response to muramyl dipeptide (GO:0032495)3.00760553
92negative T cell selection (GO:0043383)3.00758923
93positive regulation of Rap GTPase activity (GO:0032854)2.99981100
94regulation of ARF protein signal transduction (GO:0032012)2.97411929
95tolerance induction (GO:0002507)2.95883562
96production of molecular mediator involved in inflammatory response (GO:0002532)2.94757592
97long-term memory (GO:0007616)2.94348758
98regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.93750583
99negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.92690905
100negative regulation of T-helper cell differentiation (GO:0045623)2.92690905
101exploration behavior (GO:0035640)2.92617987
102leukocyte degranulation (GO:0043299)2.92373482
103positive regulation of B cell differentiation (GO:0045579)2.91731901
104positive regulation of membrane potential (GO:0045838)2.90424493
105defense response to protozoan (GO:0042832)2.89947332
106thymic T cell selection (GO:0045061)2.89609773
107regulation of long-term neuronal synaptic plasticity (GO:0048169)2.89043479
108T cell selection (GO:0045058)2.88071067
109positive T cell selection (GO:0043368)2.87135104
110regulation of tolerance induction (GO:0002643)2.85475356
111antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.85384456
112interferon-gamma-mediated signaling pathway (GO:0060333)2.84270192
113regulation of T cell mediated cytotoxicity (GO:0001914)2.83444566
114regulation of dendritic cell antigen processing and presentation (GO:0002604)2.82217174
115cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.81530177
116regulation of mast cell activation (GO:0033003)2.80383792
117synaptic transmission, glutamatergic (GO:0035249)2.78436759
118regulation of natural killer cell mediated immunity (GO:0002715)2.77572989
119regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.77572989
120negative regulation of innate immune response (GO:0045824)2.77440776
121membrane depolarization during action potential (GO:0086010)2.77225516
122activated T cell proliferation (GO:0050798)2.74786843
123glutamate receptor signaling pathway (GO:0007215)2.74637656
124potassium ion import (GO:0010107)2.74008137
125regulation of vesicle fusion (GO:0031338)2.73947548
126positive regulation of T cell mediated cytotoxicity (GO:0001916)2.71375852
127positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.70556843
128negative regulation of glycoprotein biosynthetic process (GO:0010561)2.70394023
129glycine transport (GO:0015816)2.69228214
130positive regulation of mast cell activation involved in immune response (GO:0033008)2.68512775
131positive regulation of mast cell degranulation (GO:0043306)2.68512775
132positive regulation of gamma-delta T cell activation (GO:0046645)2.65731482
133membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.65255675
134regulation of neurotransmitter secretion (GO:0046928)2.64982373
135regulation of amyloid precursor protein catabolic process (GO:1902991)2.64569672
136regulation of excitatory postsynaptic membrane potential (GO:0060079)2.63291801
137adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.62943249
138gamma-aminobutyric acid transport (GO:0015812)2.60632632
139neurotransmitter transport (GO:0006836)2.60049719
140regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.59607707
141neuron-neuron synaptic transmission (GO:0007270)2.55785271
142detection of temperature stimulus involved in sensory perception (GO:0050961)2.53721749
143detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.53721749
144mucosal-associated lymphoid tissue development (GO:0048537)2.53350870
145Peyers patch development (GO:0048541)2.53350870
146regulation of voltage-gated calcium channel activity (GO:1901385)2.51394994
147regulation of neurotransmitter levels (GO:0001505)2.48884936
148regulation of synaptic plasticity (GO:0048167)2.48267351
149regulation of neuron projection regeneration (GO:0070570)2.46811186
150regulation of axon regeneration (GO:0048679)2.46811186
151positive regulation of catecholamine secretion (GO:0033605)2.45292174
152positive regulation of synaptic transmission, GABAergic (GO:0032230)2.43680656
153neuron cell-cell adhesion (GO:0007158)2.42930916
154regulation of postsynaptic membrane potential (GO:0060078)2.42762051
155regulation of neurotransmitter transport (GO:0051588)2.40002949
156antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.39979915
157antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.39979915
158membrane depolarization (GO:0051899)2.39807164
159layer formation in cerebral cortex (GO:0021819)2.38309424
160negative regulation of dendrite morphogenesis (GO:0050774)2.37886545
161regulation of regulatory T cell differentiation (GO:0045589)2.37808109
162regulation of beta-amyloid formation (GO:1902003)2.37299394
163regulation of gamma-delta T cell differentiation (GO:0045586)2.36909140
164positive regulation of potassium ion transmembrane transport (GO:1901381)2.36500820
165negative regulation of synaptic transmission, GABAergic (GO:0032229)2.36328321
166adult walking behavior (GO:0007628)2.36017856
167cellular sodium ion homeostasis (GO:0006883)2.35856948
168antigen processing and presentation via MHC class Ib (GO:0002475)2.35709885
169cell communication by electrical coupling (GO:0010644)2.33302785
170positive regulation of neurotransmitter secretion (GO:0001956)2.32349862
171positive regulation of vesicle fusion (GO:0031340)2.32278522
172calcium-mediated signaling using intracellular calcium source (GO:0035584)2.30621068
173long-term synaptic potentiation (GO:0060291)2.30003795
174positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.28365813
175suckling behavior (GO:0001967)2.26971091
176negative regulation of type 2 immune response (GO:0002829)2.26949511
177synaptic vesicle endocytosis (GO:0048488)2.26540990
178regulation of calcium ion transmembrane transport (GO:1903169)2.26499208
179regulation of calcium ion transmembrane transporter activity (GO:1901019)2.26499208
180positive regulation of neurotransmitter transport (GO:0051590)2.25933427
181regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.25652537
182gamma-aminobutyric acid signaling pathway (GO:0007214)2.24764367
183calcium ion-dependent exocytosis (GO:0017156)2.23470810
184response to interleukin-15 (GO:0070672)2.23262971
185detection of calcium ion (GO:0005513)2.22714007
186regulation of ARF GTPase activity (GO:0032312)2.22339416

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.75785399
2BP1_19119308_ChIP-ChIP_Hs578T_Human3.83094934
3IKZF1_21737484_ChIP-ChIP_HCT116_Human2.96452593
4IRF8_21731497_ChIP-ChIP_J774_Mouse2.62891819
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.44558887
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.37772596
7SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.36196167
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.34515321
9MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.29489291
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.26742220
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.25823420
12RARB_27405468_Chip-Seq_BRAIN_Mouse2.25121983
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.23468856
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22559297
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.18068294
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.17937961
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.13861768
18RNF2_18974828_ChIP-Seq_MESCs_Mouse2.13861768
19IRF8_27001747_Chip-Seq_BMDM_Mouse2.12498598
20DROSHA_22980978_ChIP-Seq_HELA_Human2.09572652
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.06497409
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.01034383
23* RUNX1_22412390_ChIP-Seq_EML_Mouse2.00268476
24EZH2_27294783_Chip-Seq_ESCs_Mouse1.97515292
25NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.95326348
26SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.93766313
27REST_21632747_ChIP-Seq_MESCs_Mouse1.92416223
28KDM2B_26808549_Chip-Seq_SUP-B15_Human1.92203375
29DNAJC2_21179169_ChIP-ChIP_NT2_Human1.90438369
30GATA1_22025678_ChIP-Seq_K562_Human1.87580939
31MAF_26560356_Chip-Seq_TH2_Human1.81549412
32MYB_21317192_ChIP-Seq_ERMYB_Mouse1.80725380
33* SPI1_23547873_ChIP-Seq_NB4_Human1.80687511
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.79000294
35SCL_19346495_ChIP-Seq_HPC-7_Human1.77306711
36SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.77189294
37NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.74851229
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.72696983
39MYB_26560356_Chip-Seq_TH2_Human1.72531628
40RUNX_20019798_ChIP-Seq_JUKART_Human1.70301109
41GATA1_19941827_ChIP-Seq_MEL_Mouse1.69716633
42IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.68736376
43EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67315008
44LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.64441862
45RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.63337545
46EZH2_27304074_Chip-Seq_ESCs_Mouse1.62861856
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.61910141
48RNF2_27304074_Chip-Seq_ESCs_Mouse1.59614071
49STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.57847940
50LXR_22292898_ChIP-Seq_THP-1_Human1.56110555
51STAT4_19710469_ChIP-ChIP_TH1__Mouse1.55135388
52KDM2B_26808549_Chip-Seq_DND41_Human1.54704997
53MYB_26560356_Chip-Seq_TH1_Human1.52778234
54KDM2B_26808549_Chip-Seq_K562_Human1.52614703
55GATA1_19941826_ChIP-Seq_K562_Human1.49413442
56CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.47695431
57GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.46683823
58E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.46428746
59STAT6_21828071_ChIP-Seq_BEAS2B_Human1.46285023
60MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.43335530
61VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.41585405
62EED_16625203_ChIP-ChIP_MESCs_Mouse1.40148524
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.36641987
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34847347
65* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.33654562
66GATA3_27048872_Chip-Seq_THYMUS_Human1.32985086
67FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.30520906
68SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30454647
69SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30188893
70CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29674909
71TCF7_22412390_ChIP-Seq_EML_Mouse1.28467082
72PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26486290
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.24284198
74NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.23923052
75PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23812188
76VDR_21846776_ChIP-Seq_THP-1_Human1.23034476
77PU.1_20513432_ChIP-Seq_Bcells_Mouse1.22185353
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.21470591
79GATA1_22383799_ChIP-Seq_G1ME_Mouse1.21102538
80KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.19998229
81KDM2B_26808549_Chip-Seq_JURKAT_Human1.19575788
82VDR_24787735_ChIP-Seq_THP-1_Human1.18976385
83CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18878221
84ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.17775583
85CTCF_27219007_Chip-Seq_Bcells_Human1.17066829
86* ELF1_20517297_ChIP-Seq_JURKAT_Human1.15707985
87TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.15271410
88* RACK7_27058665_Chip-Seq_MCF-7_Human1.14760483
89* SPI1_23127762_ChIP-Seq_K562_Human1.13400525
90GBX2_23144817_ChIP-Seq_PC3_Human1.13369604
91KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.13292023
92VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.12995946
93KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.12605843
94RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.11151573
95* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11018357
96MAF_26560356_Chip-Seq_TH1_Human1.09306209
97* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08406091
98CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06648498
99CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05623233
100LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.04862541
101* SA1_27219007_Chip-Seq_ERYTHROID_Human1.03360276
102MYC_22102868_ChIP-Seq_BL_Human1.02676460
103ZFP281_18757296_ChIP-ChIP_E14_Mouse1.02560998
104SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02108407
105CTCF_27219007_Chip-Seq_ERYTHROID_Human1.01874813
106* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00906041
107Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.00856543
108OCT4_19829295_ChIP-Seq_ESCs_Human1.00452843
109PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.00436027
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.99903419
111CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98079448
112UTX_26944678_Chip-Seq_JUKART_Human0.97193685
113SMC4_20622854_ChIP-Seq_HELA_Human0.96787203
114GATA2_19941826_ChIP-Seq_K562_Human0.96312502
115RARG_19884340_ChIP-ChIP_MEFs_Mouse0.94252363
116IRF8_22096565_ChIP-ChIP_GC-B_Human0.94096472
117MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94041312
118* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93050811
119SA1_27219007_Chip-Seq_Bcells_Human0.92844312
120WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92193123
121RING1B_27294783_Chip-Seq_ESCs_Mouse0.91697598
122RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.91092797
123NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.88974893
124GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88760926
125NR3C1_23031785_ChIP-Seq_PC12_Mouse0.88659305
126TET1_21490601_ChIP-Seq_MESCs_Mouse0.88058054
127* BCL6_27268052_Chip-Seq_Bcells_Human0.87483426
128VDR_24763502_ChIP-Seq_THP-1_Human0.86796188
129MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.86530815
130EGR1_19032775_ChIP-ChIP_M12_Human0.86198224
131ELK3_25401928_ChIP-Seq_HUVEC_Human0.85727440
132PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.85204856
133P68_20966046_ChIP-Seq_HELA_Human0.83718134
134TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82760032
135FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.82091682
136GATA2_21666600_ChIP-Seq_HMVEC_Human0.81856257
137SRY_22984422_ChIP-ChIP_TESTIS_Rat0.81727947
138OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.78090104
139CTCF_21964334_ChIP-Seq_BJAB-B_Human0.76962787
140SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.76893863
141BCOR_27268052_Chip-Seq_Bcells_Human0.76696918
142SMAD4_21741376_ChIP-Seq_ESCs_Human0.76630600

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.24220865
2MP0003724_increased_susceptibility_to4.48795086
3MP0003436_decreased_susceptibility_to4.06316629
4MP0003635_abnormal_synaptic_transmissio3.28041406
5MP0003880_abnormal_central_pattern3.22449182
6MP0001968_abnormal_touch/_nociception3.13409768
7MP0004270_analgesia3.06181793
8MP0002735_abnormal_chemical_nociception2.85543957
9MP0002419_abnormal_innate_immunity2.78533661
10MP0009745_abnormal_behavioral_response2.59914386
11MP0002064_seizures2.51897870
12MP0002736_abnormal_nociception_after2.51571953
13MP0002272_abnormal_nervous_system2.35479615
14MP0002063_abnormal_learning/memory/cond2.35374820
15MP0008569_lethality_at_weaning2.32909588
16MP0006082_CNS_inflammation2.18565795
17MP0002733_abnormal_thermal_nociception2.17755867
18MP0008260_abnormal_autophagy2.17626646
19MP0009046_muscle_twitch2.14246462
20MP0002909_abnormal_adrenal_gland2.09819201
21MP0001970_abnormal_pain_threshold2.08560832
22MP0002734_abnormal_mechanical_nocicepti2.08537614
23MP0002572_abnormal_emotion/affect_behav2.04135735
24MP0003656_abnormal_erythrocyte_physiolo2.04073264
25MP0003300_gastrointestinal_ulcer2.01431232
26MP0001533_abnormal_skeleton_physiology1.98824290
27MP0003172_abnormal_lysosome_physiology1.98263341
28MP0001501_abnormal_sleep_pattern1.94461023
29MP0003879_abnormal_hair_cell1.92428254
30MP0002148_abnormal_hypersensitivity_rea1.92357212
31MP0004510_myositis1.92267173
32MP0002132_abnormal_respiratory_system1.88026427
33MP0002405_respiratory_system_inflammati1.80594848
34MP0009278_abnormal_bone_marrow1.80446777
35MP0002822_catalepsy1.78938467
36MP0002067_abnormal_sensory_capabilities1.77326738
37MP0005423_abnormal_somatic_nervous1.71659068
38MP0010155_abnormal_intestine_physiology1.69835464
39MP0003329_amyloid_beta_deposits1.66333285
40MP0001486_abnormal_startle_reflex1.64849170
41MP0004858_abnormal_nervous_system1.60822346
42MP0003690_abnormal_glial_cell1.60402111
43MP0000465_gastrointestinal_hemorrhage1.59117652
44MP0006276_abnormal_autonomic_nervous1.57524743
45MP0004947_skin_inflammation1.54140818
46MP0004147_increased_porphyrin_level1.51493879
47MP0001845_abnormal_inflammatory_respons1.50052908
48MP0004381_abnormal_hair_follicle1.48077138
49MP0009333_abnormal_splenocyte_physiolog1.47439465
50MP0001986_abnormal_taste_sensitivity1.46320324
51MP0001984_abnormal_olfaction1.45770537
52MP0001440_abnormal_grooming_behavior1.45103332
53MP0000685_abnormal_immune_system1.43927003
54MP0005671_abnormal_response_to1.43175181
55MP0008874_decreased_physiological_sensi1.42409487
56MP0003633_abnormal_nervous_system1.42322477
57MP0000689_abnormal_spleen_morphology1.41995238
58MP0002722_abnormal_immune_system1.40816663
59MP0002429_abnormal_blood_cell1.36080953
60MP0000703_abnormal_thymus_morphology1.36043135
61MP0001502_abnormal_circadian_rhythm1.34551725
62MP0005451_abnormal_body_composition1.32299887
63MP0004145_abnormal_muscle_electrophysio1.32270390
64MP0003828_pulmonary_edema1.31764395
65MP0001851_eye_inflammation1.30831099
66MP0002396_abnormal_hematopoietic_system1.29240717
67MP0004811_abnormal_neuron_physiology1.28714136
68MP0002557_abnormal_social/conspecific_i1.28486986
69MP0002277_abnormal_respiratory_mucosa1.28100646
70MP0004142_abnormal_muscle_tone1.27347704
71MP0003866_abnormal_defecation1.24647775
72MP0002184_abnormal_innervation1.24172205
73MP0008961_abnormal_basal_metabolism1.22505915
74MP0000013_abnormal_adipose_tissue1.21916952
75MP0000920_abnormal_myelination1.19122494
76MP0005645_abnormal_hypothalamus_physiol1.19110052
77MP0008469_abnormal_protein_level1.18622257
78MP0001545_abnormal_hematopoietic_system1.18277615
79MP0005397_hematopoietic_system_phenotyp1.18277615
80MP0003075_altered_response_to1.17583657
81MP0001905_abnormal_dopamine_level1.15459810
82MP0009764_decreased_sensitivity_to1.14146145
83MP0000955_abnormal_spinal_cord1.11087171
84MP0002837_dystrophic_cardiac_calcinosis1.10552510
85MP0005386_behavior/neurological_phenoty1.09967151
86MP0004924_abnormal_behavior1.09967151
87MP0004130_abnormal_muscle_cell1.09516132
88MP0004883_abnormal_blood_vessel1.09207443
89MP0001790_abnormal_immune_system1.09182664
90MP0005387_immune_system_phenotype1.09182664
91MP0005535_abnormal_body_temperature1.08007458
92MP0000751_myopathy1.07174152
93MP0002066_abnormal_motor_capabilities/c1.06109526
94MP0002998_abnormal_bone_remodeling1.05916578
95MP0005646_abnormal_pituitary_gland0.97927402
96MP0001800_abnormal_humoral_immune0.97445795
97MP0001835_abnormal_antigen_presentation0.96381027
98MP0002882_abnormal_neuron_morphology0.95992468
99MP0001873_stomach_inflammation0.95855866
100MP0003763_abnormal_thymus_physiology0.95680771
101MP0002229_neurodegeneration0.95039166
102MP0003045_fibrosis0.94193953
103MP0000747_muscle_weakness0.93898087
104MP0008004_abnormal_stomach_pH0.93614435
105MP0004885_abnormal_endolymph0.93604734
106MP0002933_joint_inflammation0.92119259
107MP0000858_altered_metastatic_potential0.91577531
108MP0009785_altered_susceptibility_to0.91109598
109MP0002420_abnormal_adaptive_immunity0.90664837
110MP0003631_nervous_system_phenotype0.89625853
111MP0008872_abnormal_physiological_respon0.89065052
112MP0001765_abnormal_ion_homeostasis0.88719802
113MP0001819_abnormal_immune_cell0.87544680
114MP0005464_abnormal_platelet_physiology0.87474465
115MP0002723_abnormal_immune_serum0.87266122
116MP0002398_abnormal_bone_marrow0.86511975
117MP0005310_abnormal_salivary_gland0.84786505
118MP0005000_abnormal_immune_tolerance0.83742171
119MP0001663_abnormal_digestive_system0.83546726
120MP0003878_abnormal_ear_physiology0.82856929
121MP0005377_hearing/vestibular/ear_phenot0.82856929
122MP0001348_abnormal_lacrimal_gland0.82424214
123MP0003183_abnormal_peptide_metabolism0.80554034
124MP0000604_amyloidosis0.80294706
125MP0005390_skeleton_phenotype0.80169065
126MP0010234_abnormal_vibrissa_follicle0.78899747
127MP0002069_abnormal_eating/drinking_beha0.78331624
128MP0004484_altered_response_of0.77759239
129MP0002653_abnormal_ependyma_morphology0.77720578
130MP0005025_abnormal_response_to0.77102030
131MP0005083_abnormal_biliary_tract0.76904984
132MP0005075_abnormal_melanosome_morpholog0.76486071
133MP0003646_muscle_fatigue0.76086378
134MP0005164_abnormal_response_to0.75854601
135MP0000716_abnormal_immune_system0.74816104
136MP0010386_abnormal_urinary_bladder0.72377014
137MP0005167_abnormal_blood-brain_barrier0.71947220
138MP0005058_abnormal_lysosome_morphology0.71825479
139MP0003191_abnormal_cellular_cholesterol0.71430821
140MP0003787_abnormal_imprinting0.71150347
141MP0001664_abnormal_digestion0.70967428
142MP0005166_decreased_susceptibility_to0.69422217
143MP0002452_abnormal_antigen_presenting0.69009906
144MP0009780_abnormal_chondrocyte_physiolo0.66260257
145MP0000343_altered_response_to0.65382894
146MP0004085_abnormal_heartbeat0.65306194
147MP0003303_peritoneal_inflammation0.64641737
148MP0005584_abnormal_enzyme/coenzyme_acti0.64349006
149MP0000249_abnormal_blood_vessel0.59685040
150MP0009763_increased_sensitivity_to0.59054557
151MP0005388_respiratory_system_phenotype0.58817136
152MP0002133_abnormal_respiratory_system0.58817136
153MP0001958_emphysema0.58629426

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.29254012
2Myokymia (HP:0002411)5.88961451
3Myositis (HP:0100614)5.30910640
4Focal motor seizures (HP:0011153)5.20759993
5Visual hallucinations (HP:0002367)5.12698096
6Recurrent abscess formation (HP:0002722)5.09054175
7Recurrent bacterial skin infections (HP:0005406)5.00785926
8Orchitis (HP:0100796)4.80429390
9Hypochromic microcytic anemia (HP:0004840)4.71832369
10Abnormality of macrophages (HP:0004311)4.61977460
11Febrile seizures (HP:0002373)4.45623940
12Retrobulbar optic neuritis (HP:0100654)4.38745013
13Optic neuritis (HP:0100653)4.38745013
14Stomatitis (HP:0010280)4.31113413
15Recurrent gram-negative bacterial infections (HP:0005420)4.27689280
16Focal seizures (HP:0007359)4.19028809
17Atonic seizures (HP:0010819)4.05691388
18Chronic obstructive pulmonary disease (HP:0006510)4.00417809
19Obstructive lung disease (HP:0006536)4.00417809
20Meningitis (HP:0001287)3.89172056
21Gastrointestinal infarctions (HP:0005244)3.86765047
22Hypochromic anemia (HP:0001931)3.81708176
23Mediastinal lymphadenopathy (HP:0100721)3.74799706
24Recurrent fungal infections (HP:0002841)3.72822468
25Increased IgE level (HP:0003212)3.69720140
26Supranuclear gaze palsy (HP:0000605)3.69673861
27Epileptic encephalopathy (HP:0200134)3.47950512
28Spontaneous hematomas (HP:0007420)3.43470996
29Cellulitis (HP:0100658)3.41725421
30Encephalitis (HP:0002383)3.39574904
31Action tremor (HP:0002345)3.38189395
32Recurrent skin infections (HP:0001581)3.36215299
33Vasculitis (HP:0002633)3.21926543
34Urticaria (HP:0001025)3.21492669
35Depression (HP:0000716)3.18263635
36Keratoconjunctivitis sicca (HP:0001097)3.17160580
37Progressive cerebellar ataxia (HP:0002073)3.15758488
38Gingivitis (HP:0000230)3.10618312
39Episodic fever (HP:0001954)3.02379657
40Chest pain (HP:0100749)2.99425174
41Anxiety (HP:0000739)2.99202592
42Recurrent cutaneous fungal infections (HP:0011370)2.99060394
43Chronic mucocutaneous candidiasis (HP:0002728)2.99060394
44Progressive inability to walk (HP:0002505)2.97305643
45Keratoconjunctivitis (HP:0001096)2.94062739
46Ankle clonus (HP:0011448)2.90713428
47Inflammation of the large intestine (HP:0002037)2.81975155
48Scanning speech (HP:0002168)2.81539777
49Absence seizures (HP:0002121)2.77978254
50Microcytic anemia (HP:0001935)2.77918125
51Truncal ataxia (HP:0002078)2.75750860
52Papilledema (HP:0001085)2.66450192
53Pustule (HP:0200039)2.65874516
54Dysmetria (HP:0001310)2.64275187
55Pulmonary infiltrates (HP:0002113)2.64008471
56Recurrent bronchitis (HP:0002837)2.63205901
57Chronic otitis media (HP:0000389)2.62150936
58Agammaglobulinemia (HP:0004432)2.61893658
59Psychosis (HP:0000709)2.61543618
60Epistaxis (HP:0000421)2.61038536
61Hypercortisolism (HP:0001578)2.60879764
62Postural instability (HP:0002172)2.59602926
63Generalized tonic-clonic seizures (HP:0002069)2.59257059
64Gingival bleeding (HP:0000225)2.57782031
65Hemoptysis (HP:0002105)2.56567626
66Dialeptic seizures (HP:0011146)2.54333773
67Pulmonary embolism (HP:0002204)2.53241141
68T lymphocytopenia (HP:0005403)2.50138898
69Leukocytosis (HP:0001974)2.48288741
70Ventricular fibrillation (HP:0001663)2.45960677
71Slow saccadic eye movements (HP:0000514)2.42115742
72Poor eye contact (HP:0000817)2.41490484
73Peritonitis (HP:0002586)2.40821506
74Petechiae (HP:0000967)2.39929464
75Amyloidosis (HP:0011034)2.39190991
76Abnormality of T cell number (HP:0011839)2.38271914
77Osteomyelitis (HP:0002754)2.36746198
78Granulocytopenia (HP:0001913)2.35807485
79Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.35583543
80Abnormal social behavior (HP:0012433)2.35397738
81Impaired social interactions (HP:0000735)2.35397738
82Growth hormone excess (HP:0000845)2.33895093
83Abnormality of the heme biosynthetic pathway (HP:0010472)2.33802618
84Hypothermia (HP:0002045)2.33219312
85Purpura (HP:0000979)2.32838131
86Sepsis (HP:0100806)2.32608688
87Myotonia (HP:0002486)2.30216489
88Recurrent viral infections (HP:0004429)2.29836418
89Spinal canal stenosis (HP:0003416)2.29712109
90Obstructive sleep apnea (HP:0002870)2.28682459
91Focal dystonia (HP:0004373)2.26786019
92Papilloma (HP:0012740)2.26223277
93Verrucae (HP:0200043)2.26223277
94Panhypogammaglobulinemia (HP:0003139)2.24350338
95Gaze-evoked nystagmus (HP:0000640)2.24283042
96Torticollis (HP:0000473)2.23573997
97Abnormal eating behavior (HP:0100738)2.23531048
98Colitis (HP:0002583)2.23442574
99Arterial thrombosis (HP:0004420)2.21777805
100Prolonged bleeding time (HP:0003010)2.20416963
101Abnormality of T cells (HP:0002843)2.20217488
102Status epilepticus (HP:0002133)2.20188283
103Lymphopenia (HP:0001888)2.19805447
104Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.19069094
105Anorexia (HP:0002039)2.18405321
106Chronic sinusitis (HP:0011109)2.17936087
107Increased IgM level (HP:0003496)2.17203380
108Broad-based gait (HP:0002136)2.14788151
109Abnormality of the nasal mucosa (HP:0000433)2.14051756
110Craniofacial dystonia (HP:0012179)2.10785392
111Agitation (HP:0000713)2.10457099
112Dysdiadochokinesis (HP:0002075)2.10050433
113Intention tremor (HP:0002080)2.08265056
114Exercise-induced myalgia (HP:0003738)2.08127785
115Rapidly progressive (HP:0003678)2.07944557
116Rigidity (HP:0002063)2.07134035
117Diplopia (HP:0000651)2.07063756
118Abnormality of binocular vision (HP:0011514)2.07063756
119Hemiplegia (HP:0002301)2.06595433
120Hypergammaglobulinemia (HP:0010702)2.06036551
121Vertigo (HP:0002321)2.04933437
122Nasal polyposis (HP:0100582)2.04842547
123Mutism (HP:0002300)2.04660100
124Bradykinesia (HP:0002067)2.02613584
125Abnormality of the pleura (HP:0002103)2.02104310
126Annular pancreas (HP:0001734)2.02076180
127Acne (HP:0001061)2.01515393
128Loss of speech (HP:0002371)2.01441834
129Neuroendocrine neoplasm (HP:0100634)2.00761251
130Gastrointestinal stroma tumor (HP:0100723)2.00700459
131Retinal dysplasia (HP:0007973)2.00204503
132Abnormality of cells of the lymphoid lineage (HP:0012140)1.98357776
133Nonprogressive disorder (HP:0003680)1.97774855
134Menstrual irregularities (HP:0000858)1.97539205
135Impaired smooth pursuit (HP:0007772)1.97180329
136Decreased circulating renin level (HP:0003351)1.97023107
137Difficulty running (HP:0009046)1.95727296
138Delusions (HP:0000746)1.95091944
139Polycythemia (HP:0001901)1.94982478
140Absent rod-and cone-mediated responses on ERG (HP:0007688)1.94779164
141Stereotypic behavior (HP:0000733)1.94177338
142Adrenal overactivity (HP:0002717)1.94049941
143Insomnia (HP:0100785)1.93697917
144Spastic gait (HP:0002064)1.93456519
145Amblyopia (HP:0000646)1.93407429
146Inability to walk (HP:0002540)1.93169345
147Urinary urgency (HP:0000012)1.91298416
148Abnormality of the peritoneum (HP:0002585)1.91152331
149Bundle branch block (HP:0011710)1.88698994
150Premature loss of primary teeth (HP:0006323)1.87566729
151Eosinophilia (HP:0001880)1.87390807
152Impaired vibration sensation in the lower limbs (HP:0002166)1.86324380
153Elevated erythrocyte sedimentation rate (HP:0003565)1.86258954
154Restrictive lung disease (HP:0002091)1.83402395
155Abnormality of the endocardium (HP:0004306)1.83315282
156IgM deficiency (HP:0002850)1.83088179
157Segmental peripheral demyelination/remyelination (HP:0003481)1.82773099
158Gangrene (HP:0100758)1.82691186
159Skin ulcer (HP:0200042)1.81548999
160Abnormality of T cell physiology (HP:0011840)1.79957786
161Poikilocytosis (HP:0004447)1.79450699
162Bronchitis (HP:0012387)1.78601638
163Glomerulopathy (HP:0100820)1.77333427
164Progressive microcephaly (HP:0000253)1.76782598
165Abnormality of the pericardium (HP:0001697)1.76593337
166Oligomenorrhea (HP:0000876)1.75980319
167Erythema (HP:0010783)1.75922083
168Abnormality of magnesium homeostasis (HP:0004921)1.75397887
169Pheochromocytoma (HP:0002666)1.74086514
170Neurofibrillary tangles (HP:0002185)1.73460265
171Abnormal delayed hypersensitivity skin test (HP:0002963)1.72276665
172Deep palmar crease (HP:0006191)1.72099494
173Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.69940987
174Failure to thrive in infancy (HP:0001531)1.69779229
175Limb dystonia (HP:0002451)1.68917970
176Urinary bladder sphincter dysfunction (HP:0002839)1.68770663
177Peripheral hypomyelination (HP:0007182)1.67289760
178Abnormality of saccadic eye movements (HP:0000570)1.67277413
179Gastrointestinal inflammation (HP:0004386)1.65593317

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K123.07505255
2NTRK32.85513298
3RIPK42.84302402
4MAP3K92.80729036
5IRAK42.44995086
6CDK192.43216369
7ARAF2.43137787
8KSR22.34309531
9BLK2.29236534
10CSK2.07050696
11DAPK22.03032059
12CAMKK21.98730992
13SIK21.94060027
14MAP4K11.89856076
15GRK51.88691250
16PINK11.87016324
17EPHB11.83604919
18MAP3K131.83013389
19EPHA41.81876813
20MAP2K71.75492366
21TNIK1.67997186
22FES1.55983244
23CAMKK11.54608325
24MAP2K41.51377488
25MAPKAPK31.50420548
26MAP3K31.49203724
27TNK21.47840310
28MAP3K21.46998975
29NTRK11.44113039
30MINK11.40888075
31MAP3K11.39549793
32CAMK11.34490101
33JAK31.31355340
34SYK1.28654559
35TAOK11.28093596
36NTRK21.22420731
37MAP3K41.22153843
38FGR1.20057523
39DAPK11.18774350
40PRPF4B1.16164220
41SIK31.16149464
42TAOK31.13271300
43PRKCH1.12619727
44MARK31.12027181
45MARK21.10547006
46GRK61.09540807
47ZAP701.06352713
48RET1.06228646
49MUSK1.04423643
50HIPK21.04215451
51LYN1.03769414
52PAK61.03342391
53EEF2K1.03321088
54CDK50.99370505
55RAF10.99071974
56PDK10.98716929
57SIK10.93337064
58MAP3K70.90240473
59TAOK20.90223874
60PHKG20.88281881
61PHKG10.88281881
62IKBKE0.86032800
63MAPK130.85933304
64PTK60.84751190
65TRIB30.84170369
66UHMK10.83378145
67PDPK10.82942347
68RIPK10.82369804
69ADRBK20.81858069
70SGK2230.81564493
71SGK4940.81564493
72MAP3K140.79895808
73DYRK1B0.79363325
74STK380.78660204
75MAPKAPK50.78262989
76IRAK20.77845195
77MAPK120.76552421
78MAP2K60.74498759
79CSF1R0.74228310
80TESK20.71950826
81TBK10.71867723
82SMG10.70755769
83KIT0.70501714
84BTK0.70357942
85PRKD20.70294718
86PRKD30.69538394
87DAPK30.66886283
88MAP2K30.65723251
89MAP3K110.63076514
90SGK30.61815968
91RPS6KA20.61731763
92MAPK70.61359137
93HCK0.60751706
94SGK20.60736751
95PRKCQ0.60109149
96CDC42BPA0.59997253
97STK110.59648776
98CAMK40.59594006
99YES10.59464343
100KSR10.59333804
101MATK0.57922680
102IKBKB0.57081474
103MAP3K60.56568014
104TYK20.54796047
105TEC0.53529129
106ITK0.53284386
107TGFBR20.53245911
108NLK0.53215757
109TXK0.53089688
110MAP3K100.52614246
111JAK10.52578537
112PTK2B0.52560868
113JAK20.52433144
114PRKG20.52377774
115LCK0.51933372
116CAMK1G0.51572199
117ERN10.50293533
118LMTK20.48716921
119PRKCZ0.48593832
120PRKCG0.47671506
121MAP2K10.46639693
122MAP2K20.46486031
123RPS6KC10.45616095
124RPS6KL10.45616095
125IRAK10.45308699
126FGFR40.44681103
127WNK10.42802972
128FYN0.42079272
129CAMK2A0.41882162
130PRKD10.40285672
131CAMK2G0.39815937
132BMX0.39402887
133LRRK20.37601883
134BMPR20.36624931

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047212.78112757
2Olfactory transduction_Homo sapiens_hsa047402.59071353
3Leishmaniasis_Homo sapiens_hsa051402.43003306
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.32224639
5Circadian entrainment_Homo sapiens_hsa047132.23978364
6Long-term potentiation_Homo sapiens_hsa047202.23024541
7Staphylococcus aureus infection_Homo sapiens_hsa051502.20725991
8Nicotine addiction_Homo sapiens_hsa050332.09984893
9Graft-versus-host disease_Homo sapiens_hsa053322.09083574
10Morphine addiction_Homo sapiens_hsa050322.05387557
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.04545379
12Allograft rejection_Homo sapiens_hsa053302.02342681
13Glutamatergic synapse_Homo sapiens_hsa047242.00349706
14Salivary secretion_Homo sapiens_hsa049701.94634756
15GABAergic synapse_Homo sapiens_hsa047271.92012884
16Autoimmune thyroid disease_Homo sapiens_hsa053201.90588326
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.88258453
18Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.79078186
19Insulin secretion_Homo sapiens_hsa049111.77701619
20Gastric acid secretion_Homo sapiens_hsa049711.75618566
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.74964501
22Amphetamine addiction_Homo sapiens_hsa050311.69637358
23Dopaminergic synapse_Homo sapiens_hsa047281.68367048
24Taste transduction_Homo sapiens_hsa047421.62685875
25Toll-like receptor signaling pathway_Homo sapiens_hsa046201.62303231
26Cholinergic synapse_Homo sapiens_hsa047251.56307563
27Type I diabetes mellitus_Homo sapiens_hsa049401.54891996
28Malaria_Homo sapiens_hsa051441.54821999
29Long-term depression_Homo sapiens_hsa047301.45925749
30Primary immunodeficiency_Homo sapiens_hsa053401.45101535
31Phosphatidylinositol signaling system_Homo sapiens_hsa040701.41392855
32Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.40075364
33Oxytocin signaling pathway_Homo sapiens_hsa049211.39632398
34Collecting duct acid secretion_Homo sapiens_hsa049661.39163706
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.38000831
36Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.37100725
37Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.35398552
38Calcium signaling pathway_Homo sapiens_hsa040201.34880297
39B cell receptor signaling pathway_Homo sapiens_hsa046621.34252032
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.31575869
41GnRH signaling pathway_Homo sapiens_hsa049121.31387970
42Renin secretion_Homo sapiens_hsa049241.28231286
43NOD-like receptor signaling pathway_Homo sapiens_hsa046211.26549092
44Measles_Homo sapiens_hsa051621.25686154
45Antigen processing and presentation_Homo sapiens_hsa046121.25440822
46Serotonergic synapse_Homo sapiens_hsa047261.23822815
47Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.21763741
48Toxoplasmosis_Homo sapiens_hsa051451.21556702
49African trypanosomiasis_Homo sapiens_hsa051431.19703220
50cAMP signaling pathway_Homo sapiens_hsa040241.19249779
51Viral myocarditis_Homo sapiens_hsa054161.18844104
52NF-kappa B signaling pathway_Homo sapiens_hsa040641.16956547
53Leukocyte transendothelial migration_Homo sapiens_hsa046701.15050572
54Phagosome_Homo sapiens_hsa041451.10294249
55Cocaine addiction_Homo sapiens_hsa050301.09276112
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.09200945
57SNARE interactions in vesicular transport_Homo sapiens_hsa041301.08329010
58Influenza A_Homo sapiens_hsa051641.07568255
59Neurotrophin signaling pathway_Homo sapiens_hsa047221.06630364
60VEGF signaling pathway_Homo sapiens_hsa043701.04969504
61Intestinal immune network for IgA production_Homo sapiens_hsa046721.04503542
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.03865522
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.03305888
64Jak-STAT signaling pathway_Homo sapiens_hsa046301.02680436
65Pancreatic secretion_Homo sapiens_hsa049721.01506356
66Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.01263630
67Estrogen signaling pathway_Homo sapiens_hsa049150.97684956
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.96179548
69T cell receptor signaling pathway_Homo sapiens_hsa046600.95683888
70Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95432155
71TNF signaling pathway_Homo sapiens_hsa046680.95268884
72Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.94318205
73Herpes simplex infection_Homo sapiens_hsa051680.94300046
74Other glycan degradation_Homo sapiens_hsa005110.93764599
75Type II diabetes mellitus_Homo sapiens_hsa049300.92287136
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.92190427
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89772368
78Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.89434410
79Hepatitis C_Homo sapiens_hsa051600.89308315
80Glioma_Homo sapiens_hsa052140.88839592
81Gap junction_Homo sapiens_hsa045400.87454271
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.87393513
83Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.87086427
84Chemokine signaling pathway_Homo sapiens_hsa040620.84777720
85Asthma_Homo sapiens_hsa053100.84229718
86Platelet activation_Homo sapiens_hsa046110.82871874
87Chronic myeloid leukemia_Homo sapiens_hsa052200.80883670
88Non-small cell lung cancer_Homo sapiens_hsa052230.80062298
89Inositol phosphate metabolism_Homo sapiens_hsa005620.79771380
90Hepatitis B_Homo sapiens_hsa051610.79024329
91Notch signaling pathway_Homo sapiens_hsa043300.77598593
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77564693
93Pancreatic cancer_Homo sapiens_hsa052120.77278707
94Pertussis_Homo sapiens_hsa051330.76284194
95Choline metabolism in cancer_Homo sapiens_hsa052310.75816118
96Acute myeloid leukemia_Homo sapiens_hsa052210.75101284
97Salmonella infection_Homo sapiens_hsa051320.72374449
98Cardiac muscle contraction_Homo sapiens_hsa042600.72238039
99Legionellosis_Homo sapiens_hsa051340.72175683
100Melanogenesis_Homo sapiens_hsa049160.72106833
101Rheumatoid arthritis_Homo sapiens_hsa053230.71387808
102Osteoclast differentiation_Homo sapiens_hsa043800.70740170
103Renal cell carcinoma_Homo sapiens_hsa052110.70599145
104Thyroid hormone synthesis_Homo sapiens_hsa049180.70061839
105MAPK signaling pathway_Homo sapiens_hsa040100.69539023
106Endocytosis_Homo sapiens_hsa041440.69348178
107Prolactin signaling pathway_Homo sapiens_hsa049170.68547548
108ErbB signaling pathway_Homo sapiens_hsa040120.68149738
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.67207146
110mTOR signaling pathway_Homo sapiens_hsa041500.66464152
111Vibrio cholerae infection_Homo sapiens_hsa051100.66388150
112Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65413622
113Apoptosis_Homo sapiens_hsa042100.65211710
114Shigellosis_Homo sapiens_hsa051310.64277851
115Dorso-ventral axis formation_Homo sapiens_hsa043200.63817334
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.63208045
117Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61136725
118Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.60999851
119Insulin signaling pathway_Homo sapiens_hsa049100.59463627
120Circadian rhythm_Homo sapiens_hsa047100.59060768
121AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55486171
122Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53138370
123Rap1 signaling pathway_Homo sapiens_hsa040150.52658023
124Regulation of autophagy_Homo sapiens_hsa041400.52350357
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52316790
126Phototransduction_Homo sapiens_hsa047440.51879328
127Ras signaling pathway_Homo sapiens_hsa040140.51842748
128Adipocytokine signaling pathway_Homo sapiens_hsa049200.50659891
129Glucagon signaling pathway_Homo sapiens_hsa049220.49158581
130Hematopoietic cell lineage_Homo sapiens_hsa046400.48854604
131Alcoholism_Homo sapiens_hsa050340.46491608
132Alzheimers disease_Homo sapiens_hsa050100.46282237
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44915725
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44121265
135Thyroid cancer_Homo sapiens_hsa052160.43418714
136Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42831758
137Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.41981370
138Tuberculosis_Homo sapiens_hsa051520.40376191
139Glycerophospholipid metabolism_Homo sapiens_hsa005640.38278664
140Endometrial cancer_Homo sapiens_hsa052130.37855018
141Bile secretion_Homo sapiens_hsa049760.37680826
142FoxO signaling pathway_Homo sapiens_hsa040680.37165019

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